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- Vinayagam, Ramachandran; Xu, Baojun
- Phytomedicine 2017 v.24 pp. 119-126
- lipid peroxidation, etc ; 4',6-diamidino-2-phenylindole; Western blotting; antioxidants; apoptosis; catalase; cell viability; coumarin; diabetes; fluorescence microscopy; glucose; glycemic effect; insulin; insulin secretion; islets of Langerhans; protein synthesis; rats; staining; streptozotocin; superoxide dismutase; transcription factor NF-kappa B; Show all 21 Subjects
- ... Daphnetin (7, 8-dihydroxycoumarin), a natural coumarin compound, is known to exhibit antioxidant and anti-inflammatrory effects. However, the underlying mechanisms of its anti-apoptotic and antidiabetic effects yet not been examined. Therefore, the present work studied the anti-apoptotic and anti-diabetic effects of daphnetin by in vitro experiments.The rat insulinoma (INS-1) cells were pre-treate ...