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- Author:
- Mohammad Khalid; Mohammed H. Alqarni; Abdulrhman Alsayari; Ahmed I. Foudah; Tariq M. Aljarba; Mohammad Mukim; Mubarak A. Alamri; Shahabe Saquib Abullais; Shadma Wahab
- Source:
- Plants 2022 v.11 no.4 pp. -
- ISSN:
- 2223-7747
- Subject:
- Spondias pinnata; alpha-amylase; alpha-glucosidase; antioxidants; beta-sitosterol; bioactive compounds; chemical constituents of plants; computer simulation; databases; diabetes; diodes; flavor; fruit extracts; fruits; glucose; glycemic effect; lipid peroxidation; metformin; oleanolic acid; prediction; provenance; traditional medicine; yeasts; India
- Abstract:
- ... Spondias mangifera is a drupaceous fruit popular for its flavour and health advantages. There is little scientific knowledge about S. mangifera, despite its widespread usage in traditional medicine, in the North-Eastern region of India. Inhibiting the key carbohydrate hydrolysing enzymes is one of the strategies for managing diabetes. Therefore, this study studied the antioxidant and anti-diabetic ...
- DOI:
- 10.3390/plants11040562
- https://doi.org/10.3390/plants11040562
- Author:
- Ninon G. E. R. Etsassala; Jelili A. Badmus; Jeanine L. Marnewick; Emmanuel I. Iwuoha; Felix Nchu; Ahmed A. Hussein
- Source:
- Antioxidants 2020 v.9 no.11 pp. -
- ISSN:
- 2076-3921
- Subject:
- Salvia; absorbance; absorption; adverse effects; alpha-amylase; alpha-glucosidase; antioxidants; ascorbic acid; bioactive compounds; biological assessment; blood glucose; computer simulation; diabetic complications; digestion; diterpenoids; flavonoids; glucose; glycemic effect; hypoglycemic agents; insulin; insulin resistance; mortality; oxidative stress; oxygen radical absorbance capacity; risk reduction; spectral analysis; South Africa
- Abstract:
- ... Diabetes mellitus (DM) is one of the most dangerous metabolic diseases with a high rate of mortality worldwide. It is well known that insulin resistance and deficiency in insulin production from pancreatic β-cells are the main characteristics of DM. Due to the detrimental side effects of the current treatment, there is a considerable need to develop new effective antidiabetic drugs, especially alp ...
- DOI:
- 10.3390/antiox9111149
- https://doi.org/10.3390/antiox9111149
- Author:
- Rodrigo Rodrigues Franco; Luiz Fernando Ribeiro Zabisky; Joed Pires de Lima Júnior; Victor Hugo Mota Alves; Allisson Benatti Justino; André Lopes Saraiva; Luiz Ricardo Goulart; Foued Salmen Espindola
- Source:
- Journal of ethnopharmacology 2020 v.261 pp. 113132
- ISSN:
- 0378-8741
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Syzygium cumini; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; arginine; bioactive compounds; butanol; carboxylic ester hydrolases; catalytic activity; cytotoxicity; diabetes mellitus; enzyme inhibition; erythrocytes; ethyl acetate; fructose; glycation; glycemic effect; hexane; hyperglycemia; hyperlipidemia; inflammation; inhibitory concentration 50; kaempferol; leaves; luteolin; methylene chloride; models; oxidation; oxidative stress; quercetin; traditional medicine
- Abstract:
- ... Plant materials are commonly used in traditional medicine in order to treat various diseases such as Diabetes mellitus. Some plants, such as Syzygium cumini, have the capability to act controlling oxidative stress and protein glycation besides their potential to decrease hyperglycemia and hyperlipidemia by the inhibition of the catalysis of digestive enzymes. The aim of this study was to evaluate ...
- DOI:
- 10.1016/j.jep.2020.113132
- https://doi.org/10.1016/j.jep.2020.113132
- Author:
- Marina Fidelis; Mariana Araújo Vieira do Carmo; Thiago Mendanha da Cruz; Luciana Azevedo; Takao Myoda; Marianna Miranda Furtado; Mariza Boscacci Marques; Anderson S. Sant'Ana; Maria Inês Genovese; Won Young Oh; Mingchun Wen; Fereidoon Shahidi; Liang Zhang; Marcelo Franchin; Severino Matias de Alencar; Pedro Luiz Rosalen; Daniel Granato
- Source:
- Food chemistry 2020 v.310 pp. 125909
- ISSN:
- 0308-8146
- Subject:
- Myrciaria dubia; alpha-amylase; alpha-glucosidase; antihypertensive effect; antimicrobial properties; antioxidant activity; antioxidants; bioactive compounds; bioassays; cell culture; copper; cytotoxicity; enzyme inhibition; erythrocytes; functional properties; glycemic effect; hemolysis; humans; ingredients; low density lipoprotein; macrophages; neoplasm cells; neoplasms; oxidation; phenolic compounds; seeds; solvents; transcription factor NF-kappa B; tumor necrosis factor-alpha
- Abstract:
- ... Camu-camu (Myrciaria dubia) seeds are discarded without recovering the bioactive compounds. The main aim of the present work was to optimise the solvent mixture to extract higher total phenolic content and antioxidant capacity of camu-camu seeds. The optimised solvent system increased the extraction of phenolic compounds, in which vescalagin and castalagin were the main compounds. The optimised ex ...
- DOI:
- 10.1016/j.foodchem.2019.125909
- https://doi.org/10.1016/j.foodchem.2019.125909
- Author:
- Siow-Ping Tan; Eric Nyak-Yong Tan; Qian-Yu Lim; Mohd Azlan Nafiah
- Source:
- Journal of ethnopharmacology 2020 v.253 pp. 112610
- ISSN:
- 0378-8741
- Subject:
- Phyllanthus acidus; alpha-glucosidase; anti-inflammatory activity; antimicrobial properties; antioxidants; asthma; bioactive compounds; biomedical research; bronchitis; clinical trials; databases; diabetes; diterpenoids; edible fruits; enzyme inhibition; experimental design; glycosides; leaves; phytochemicals; rheumatoid arthritis; roots; sesquiterpenoids; toxicity; traditional medicine; triterpenoids
- Abstract:
- ... Phyllanthus acidus (L.) Skeels is not only used for its edible fruits but also used to treat a wide spectrum of diseases such as inflammatory, rheumatism, bronchitis, asthma, respiratory disorder, hepatic diseases and diabetes in India, Asia, the Caribbean region, and Central and South America. This paper aims to discuss the current understanding regarding the traditional uses, phytochemical and p ...
- DOI:
- 10.1016/j.jep.2020.112610
- https://doi.org/10.1016/j.jep.2020.112610
- Author:
- Billu Abraham; T R Reshmitha; M M Navami; Liza George; V V Venugopalan; P Nisha
- Source:
- Industrial crops and products 2020 v.151 pp. 112451
- ISSN:
- 0926-6690
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; active ingredients; alpha-amylase; alpha-glucosidase; anti-inflammatory activity; antioxidant activity; antioxidants; aspirin; bioactive compounds; dietary supplements; enzyme inhibition; epicatechin; gallic acid; inhibitory concentration 50; myoblasts; naringenin; nitric oxide; polyphenols; protein denaturation; proteinases; shikimic acid; solvents; vanillic acid
- Abstract:
- ... Dashamoola Arishta (DA), an age-old Ayurvedic formulation, is considered as panacea for inflammation-related ailments. As water is used as the solvent in DA preprations, the active ingredients are not extracted out completely and remain in the spent material (DSM). The phytochemicals extracted from DA and DSMDE using 70% (v/v) ethanol (DA & DSME respectively) were characterized using HPTLC which s ...
- DOI:
- 10.1016/j.indcrop.2020.112451
- https://doi.org/10.1016/j.indcrop.2020.112451
7. Potential Hypoglycemic Effect of Pomegranate Juice and Its Mechanism of Action: A Systematic Review
- Author:
- Carmen Alejandrina Virgen-Carrillo; Alma Gabriela Martínez Moreno; Elia Herminia Valdés Miramontes
- Source:
- Journal of medicinal food 2020 v.23 no.1 pp. 1-11
- ISSN:
- 1557-7600
- Subject:
- DNA damage; alpha-amylase; alpha-glucosidase; bioactive compounds; databases; enzyme activity; enzyme inhibition; glycemic effect; humans; in vitro studies; insulin; insulin secretion; islets of Langerhans; mechanism of action; medicinal properties; polyphenols; pomegranate juice; pomegranates; rodents; systematic review
- Abstract:
- ... Pomegranate juice (PJ) has gained popularity attributed to its phenolic compounds and their medicinal properties. Its potential hypoglycemic effect has been related to enzymatic inhibition, insulin release, and the protection of pancreatic tissue. These effects depend on several aspects, such as the content and composition of phenols in pomegranate and characteristics of the organism that consumes ...
- DOI:
- 10.1089/jmf.2019.0069
- https://doi.org/10.1089/jmf.2019.0069
- Author:
- Tânia B. Ribeiro; Ana Oliveira; Débora Campos; João Nunes; António A. Vicente; Manuela Pintado
- Source:
- Food & function 2020 v.11 no.3 pp. 2238-2254
- ISSN:
- 2042-650X
- Subject:
- alpha-glucosidase; antihypertensive effect; antioxidant activity; antioxidants; bioactive compounds; bioavailability; byproducts; cardiovascular diseases; enzyme inhibition; gastrointestinal system; in vitro digestion; ingredients; minerals; olive pomace; polyphenols; potassium; sugars; water solubility
- Abstract:
- ... Olive pomace is a semisolid by-product with great potential as a source of bioactive compounds. Using its soluble fraction, a liquid-enriched powder (LOPP) was obtained, exhibiting a rich composition in sugars, polyphenols and minerals, with potential antioxidant, antihypertensive and antidiabetic health benefits. To validate the potential of LOPP as a functional ingredient the effect of the gastr ...
- DOI:
- 10.1039/c9fo03000j
- https://doi.org/10.1039/c9fo03000j
- Author:
- Mohamad Fawzi Mahomoodally; Elwira Sieniawska; Kouadio Ibrahime Sinan; Marie Carene Nancy Picot-Allain; Serife Yerlikaya; Mehmet Cengiz Baloglu; Yasemin Celik Altunoglu; Ismail Senkardes; Kannan RR. Rengasamy; Gokhan Zengin
- Source:
- Food and chemical toxicology 2020 v.135 pp. 111052
- ISSN:
- 0278-6915
- Subject:
- Rhododendron; alpha-glucosidase; antineoplastic agents; antioxidants; bioactive compounds; cell lines; cell viability; cholinesterase; cytotoxicity; enzyme inhibition; enzyme inhibitors; epigallocatechin; ethnobotany; ethyl acetate; growth retardation; inhibitory concentration 50; lung neoplasms; methanol; neoplasm cells; poisoning; secondary metabolites; structure-activity relationships; viability assays
- Abstract:
- ... Ethnobotanical evidences report the use of Rhododendron luteum Sweet (Ericaceae) in traditional medicinal systems. However, R. luteum has been associated to the occurrence of ‘mad honey’ poisoning. In the present study, the ethyl acetate, methanol, and water extracts of R. luteum were investigated for their in vitro antioxidant, enzyme inhibition, and cytotoxic properties. The cytotoxicity of R. l ...
- DOI:
- 10.1016/j.fct.2019.111052
- https://doi.org/10.1016/j.fct.2019.111052
10. Anti-Hyperglycemic and Anticholinergic Effects of Natural Antioxidant Contents in Edible Flowers
- Author:
- Paulina Nowicka; Aneta Wojdyło
- Source:
- Antioxidants 2019 v.8 no.8 pp. -
- ISSN:
- 2076-3921
- Subject:
- Arnica; Crataegus; Lavandula; acetylcholinesterase; alpha-amylase; alpha-glucosidase; anti-aging properties; antioxidants; bioactive compounds; carotenoids; cholinesterase; edible flowers; enzyme inhibition; functional foods; glycemic effect; phenolic acids; polymers; procyanidins; triterpenoids
- Abstract:
- ... In this study, 16 selected edible flowers were evaluated for their content of bioactive compounds (polyphenols, carotenoids, triterpenoids) and for their anti-diabetic (ability to inhibit α-amylase and α-glucosidases) and anti-aging (ability to inhibit acetylcholinesterase and butyrylcholinesterase) activities. Most of the flowers analyzed in this study have not been examined in this r ...
- DOI:
- 10.3390/antiox8080308
- PubMed:
- 31443202
- PubMed Central:
- PMC6719929
- https://doi.org/10.3390/antiox8080308
- Author:
- Adriana Maite Fernández-Fernández; Amaia Iriondo-DeHond; Eduardo Dellacassa; Alejandra Medrano-Fernandez; María Dolores del Castillo
- Source:
- European food research & technology 2019 v.245 no.8 pp. 1539-1551
- ISSN:
- 1438-2377
- Subject:
- alpha-glucosidase; anthocyanins; anti-inflammatory activity; antioxidant activity; antioxidants; bioactive compounds; byproducts; chronic diseases; enzyme inhibition; ethanol; food research; grape pomace; grapes; health promotion; ingredients; inhibitory concentration 50; maceration; red wines; triacylglycerol lipase; ultrasonic treatment; wastes; winemaking
- Abstract:
- ... Winemaking industry produces large amounts of by-products (grape pomace or marc) every year, making necessary a sustainable management of such waste. Among red wines, Tannat variety possesses a unique polyphenolic profile. Consequently, the study of the bioactive properties of its by-product and the extraction optimization of its bioactive compounds is of great interest to state its health promoti ...
- DOI:
- 10.1007/s00217-019-03252-w
- https://doi.org/10.1007/s00217-019-03252-w
- Author:
- D.H. Saoud; A. Jelassi; M.B. Hlila; M.B. Goudjil; S. Ladjel; H.Ben Jannet
- Source:
- South African journal of botany 2019 v.121 pp. 386-393
- ISSN:
- 0254-6299
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Anvillea; alpha-glucosidase; antibacterial properties; antioxidant activity; antioxidants; bioactive compounds; butanol; cell lines; cytotoxicity; enzyme activity; enzyme inhibition; ethyl acetate; food industry; growth retardation; human health; inhibitory concentration 50; metabolites; neoplasm cells
- Abstract:
- ... The antioxidant, anticholinesterase, anti-tyrosinase, anti-α-glucosidase, cytotoxic, antifungal and antibacterial activities of Ethyl acetate (EtOAc) and n-butanol (n-BuOH) extracts and three compounds isolated from Anvillea radiata (Asteracea); two epimer germacranolides 9α-hydroxyparthenolide(1), 9β-hydroxyparthenolide(2) and a phenolic acid; 3,5-O-dicaffeoylquinic acid (3), were evaluated.The a ...
- DOI:
- 10.1016/j.sajb.2018.10.033
- https://doi.org/10.1016/j.sajb.2018.10.033
- Author:
- Muhammad Nadeem; Muhammad Waseem Mumtaz; Muhammad Danish; Umer Rashid; Hamid Mukhtar; Farooq Anwar; Syed Ali Raza
- Source:
- Journal of food measurement & characterization 2019 v.13 no.4 pp. 3206-3220
- ISSN:
- 2193-4126
- Subject:
- 4-hydroxybenzoic acid; Calotropis procera; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; astragalosides; binding capacity; bioactive compounds; computer simulation; dietary supplements; enzyme inhibition; ethanol; functional foods; glycemic effect; hyperglycemia; inhibitory concentration 50; kaempferol; leaf extracts; leaves; metabolites; quinic acid
- Abstract:
- ... This work aims to investigate antioxidant/antidiabetic activities of aqueous and aqueous ethanol (20–80% ethanol:water, v/v) extracts from Calotropis procera leaves followed by profiling of related bioactives using UHPLC-QTOF-MS/MS technique. Of the extracts produced, 80% ethanolic extract offered highest level of total phenolics and total flavonoids with contribution 176.31 ± 2.09 mg GAE/g DE and ...
- DOI:
- 10.1007/s11694-019-00243-z
- https://doi.org/10.1007/s11694-019-00243-z
- Author:
- Paulina Nowicka; Aneta Wojdyło
- Source:
- European food research & technology 2019 v.245 no.5 pp. 1123-1136
- ISSN:
- 1438-2377
- Subject:
- Alzheimer disease; Prunus persica; alpha-amylase; alpha-glucosidase; anti-aging properties; antioxidant activity; antioxidants; bioactive compounds; carotenoids; cholinesterase; coumaric acids; cultivars; cyanogenic glycosides; dietary supplements; glycemic effect; health promotion; noninsulin-dependent diabetes mellitus; obesity; peaches; pharmaceutical industry; polymers; procyanidins; seeds
- Abstract:
- ... In this study, the content of bioactive compounds (polyphenols and tetraterpenoids), antioxidative activity, and inhibitory activities toward α-amylase, α-glucosidase, cholinesterase of different cultivars of peach kernels were measured. Such results have not been published so far. It has been shown that peach kernels were characterized by a similar profile of bioactive compounds as the peach frui ...
- DOI:
- 10.1007/s00217-018-3214-1
- https://doi.org/10.1007/s00217-018-3214-1
- Author:
- Halah Aalim; Tarun Belwal; Lei Jiang; Hao Huang; Xianghe Meng; Zisheng Luo
- Source:
- Lebensmittel-Wissenschaft + Technologie 2019 v.103 pp. 147-154
- ISSN:
- 0023-6438
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Oryza sativa; alpha-glucosidase; amino acids; antioxidants; bioactive compounds; caffeic acid; carboxylic ester hydrolases; chlorogenic acid; chromatography; enzyme activity; enzyme inhibition; experimental design; ferulic acid; fluorescence; fructose; gallic acid; glycation; glycerol; in vitro digestion; intestines; polyphenols; response surface methodology; rice; rice bran; rice bran oil; rutin; solvents; syringic acid
- Abstract:
- ... The purpose of this investigation was to explore aqueous glycerol as food grade solvent for rice bran polyphenolic antioxidants extraction and investigate the antidiabetic and antiglycation potential of the extract and its major polyphenols. Response surface methodology (Box-Behnken design) was implemented to optimize experimental conditions for rice bran polyphenols and antioxidants extraction. T ...
- DOI:
- 10.1016/j.lwt.2019.01.006
- https://doi.org/10.1016/j.lwt.2019.01.006
- Author:
- Dammah Otieno; Salma Altuwaijri; Hye Won Kang
- Source:
- Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
- ISSN:
- 2475-2991
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; ascorbic acid; bioactive compounds; dose response; enzymatic treatment; enzyme activity; enzyme inhibition; evaporation; filtration; flowers; food plants; garlic; glucan 1,4-alpha-glucosidase; glucose; homogenization; hydrolysis; hypoglycemic agents; in vitro digestion; intestinal absorption; intestines; maltose; methanol; noninsulin-dependent diabetes mellitus; pepsin; sonication; starch; sucrose; sucrose alpha-glucosidase
- Abstract:
- ... Inhibition of carbohydrate absorption from intestine is an efficient way to prevent type 2 diabetes. Some edible plants have shown the potential as anti-diabetic agents by inhibiting carbohydrate-digestive enzymes in intestine. In terms of edible plant's health effect, bioactive compounds’ stability during the process of digestive enzymes has been commonly questioned. Therefore, the objectives of ...
- DOI:
- 10.1093/cdn/nzz031.P06-076-19
- https://doi.org/10.1093/cdn/nzz031.P06-076-19
- Author:
- Andrea Gómez‐Maqueo; Tomás García‐Cayuela; Rebeca Fernández‐López; Jorge Welti‐Chanes; M Pilar Cano
- Source:
- Journal of the science of food and agriculture 2019 v.99 no.14 pp. 6380-6391
- ISSN:
- 0022-5142
- Subject:
- Opuntia; absorption; alpha-amylase; alpha-glucosidase; anti-inflammatory activity; antioxidant activity; antioxidants; arid zones; betalains; bioactive compounds; cactus pears; cultivars; enzyme inhibition; fruits; functional foods; glucose; glycemic effect; glycosides; human health; hyperglycemia; inflammation; isorhamnetin; noninsulin-dependent diabetes mellitus; phenolic compounds; vigor
- Abstract:
- ... BACKGROUND: Prickly pears are potential candidates for the development of low‐cost functional foods because they grow with low water requirements in arid regions of the world. They are sources of betalains and phenolic compounds, which have been reported to contribute to human health. The study of the biological activity of different varieties and of their isolated bioactive constitutes is fundame ...
- DOI:
- 10.1002/jsfa.9917
- https://doi.org/10.1002/jsfa.9917
- Author:
- Nancy Dewi Yuliana; Arfina Sukmawati Arifin; Mohamad Rafi
- Source:
- Journal of food measurement & characterization 2020 v.14 no.3 pp. 1699-1707
- ISSN:
- 2193-4126
- Subject:
- Allium fistulosum; Allium schoenoprasum; Anacardium occidentale; Carica papaya; Centella asiatica; Curcuma mangga; Fourier transform infrared spectroscopy; Kaempferia galanga; Moringa oleifera; Polyscias; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; biodiversity; chloroform; enzyme inhibition; enzyme inhibitors; ethyl acetate; food crops; food plants; functional foods; hexane; inhibitory concentration 50; kaempferol; leaves; liquid chromatography; mass spectrometry; metabolomics; moieties; nuclear magnetic resonance spectroscopy; phenolic compounds; quercetin; screening; spices; vegetables; Indonesia
- Abstract:
- ... Indonesia has one of the most significant biodiversity in the world. Many edible plants have served as the sources of bioactive compounds such as α-glucosidase inhibitors and antioxidants, including several vegetables and spices. However, the potential of active biomolecules present in these food crops have not been fully explored. This study is aimed at screening α-glucosidase inhibitory and anti ...
- DOI:
- 10.1007/s11694-020-00418-z
- https://doi.org/10.1007/s11694-020-00418-z
- Author:
- Stefano Dall’Acqua; Gunes Ak; Stefania Sut; Irene Ferrarese; Gokhan Zengin; Evren Yıldıztugay; Mohamad Fawzi Mahomoodally; Kouadio Ibrahime Sinan; Devina Lobine
- Source:
- Industrial crops and products 2020 v.154 pp. 112751
- ISSN:
- 0926-6690
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Scorzonera; acarbose; acetylcholinesterase; aerial parts; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; chelating agents; cholinesterase; cosmetics; diodes; electrospray ionization mass spectrometry; enzyme inhibition; ethyl acetate; gallic acid; hexane; industrial applications; kojic acid; liquid chromatography; medicinal properties; methanol; methylene chloride; phytopharmaceuticals; polyphenols; reducing agents; root extracts; roots; rutin; solvents; traditional medicine
- Abstract:
- ... Scorzonera tomentosa L. (family Asteraceae), endemic to Turkey is reputed for its medicinal attributes in the folkloric medicine. However, only few studies on the chemical composition and pharmacological properties of this plant have been published so far. In this direction, this study aimed to shed light on the phenolic composition, antioxidant and key enzyme inhibitory properties of S. tomentosa ...
- DOI:
- 10.1016/j.indcrop.2020.112751
- https://doi.org/10.1016/j.indcrop.2020.112751
- Author:
- Tuba Acet; Kadriye Ozcan; Gokhan Zengin
- Source:
- Journal of food biochemistry 2020 v.44 no.2 pp. e13128
- ISSN:
- 0145-8884
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Helichrysum; acetylcholinesterase; alpha-amylase; alpha-glucosidase; antimicrobial properties; antioxidant activity; antioxidants; bioactive compounds; cholinesterase; enzyme inhibition; ethanol; ethyl acetate; fatty acid composition; gas chromatography; high performance liquid chromatography; methanol; novel foods; oils; palmitic acid; solvents; sulfonic acids; therapeutics; traditional medicine
- Abstract:
- ... In the present study, we aimed to search and compare the biological activities of the ethanol (EtOH), methanol (MeOH), and ethylacetate (EtOAc) solvent extracts of the flower, stem, and root parts of two Helichrysum plants (H. chionophilum (Hc) and H. plicatum subsp. plicatum (Hp)). The antioxidant properties were determined by using (2,2‐diphenyl‐1‐picrylhydrazyl) (DPPH) and ABTS (2,2′‐azino‐bis( ...
- DOI:
- 10.1111/jfbc.13128
- https://doi.org/10.1111/jfbc.13128
- Author:
- Sengul Uysal
- Source:
- Journal of food measurement & characterization 2019 v.13 no.1 pp. 162-168
- ISSN:
- 2193-4126
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Salvia absconditiflora; acetylcholinesterase; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; chemical constituents of plants; freeze drying; high performance liquid chromatography; ovens; rosmarinic acid
- Abstract:
- ... Drying method is one of the most important steps in the preparation of plant materials for phytochemical analysis and biological evaluation. In this sense, this research endeavoured to evaluate the effects three drying methods (oven, freeze, and shade drying) on phytochemical component, antioxidant, and enzyme inhibitory effects of Salvia absconditiflora Greuter & Burdet. Antioxidant activities we ...
- DOI:
- 10.1007/s11694-018-9929-7
- https://doi.org/10.1007/s11694-018-9929-7
- Author:
- Stefano Dall’Acqua; Gourav Kumar; Kouadio Ibrahime Sinan; Stefania Sut; Irene Ferrarese; Mohamad Fawzi Mahomoodally; Roumita Seebaluck-Sandoram; Ouattara Katinan Etienne; Gokhan Zengin
- Source:
- Industrial crops and products 2020 v.147 pp. 112226
- ISSN:
- 0926-6690
- Subject:
- Cochlospermum; acarbose; acetylcholinesterase; aerial parts; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; bleaching agents; cholinesterase inhibitors; diodes; electrospray ionization mass spectrometry; enzyme inhibition; gallic acid; homogenizers; kojic acid; liquid chromatography; maceration; multivariate analysis; qualitative analysis; rutin; sonication; traditional medicine
- Abstract:
- ... In African traditional medicine Cochlospermum planchonii is used to manage various diseases such as malaria, diarrhoea, jaundice, infections and inflammation, hence presents the potential to be a good source of bioactive compounds. In this study, traditional and green extraction techniques have been used namely green extraction (homogenizer assisted extraction (HAE) and Sonication (SON)) and conve ...
- DOI:
- 10.1016/j.indcrop.2020.112226
- https://doi.org/10.1016/j.indcrop.2020.112226
- Author:
- Katarina Šavikin; Jelena Živković; Ana Alimpić; Gordana Zdunić; Teodora Janković; Sonja Duletić-Laušević; Nebojša Menković
- Source:
- Industrial crops and products 2018 v.113 pp. 142-149
- ISSN:
- 0926-6690
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Punica granatum; acetylcholinesterase; agricultural wastes; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; beta-carotene; bioactive compounds; butanol; ellagic acid; ethyl acetate; fractionation; gallic acid; inhibitory concentration 50; liquids; petroleum; polyphenols; pomegranates; tannins
- Abstract:
- ... Pomegranate (Punica granatum L.) peel is a rich source of polyphenols, especially tannins, and concentrations of these compounds may be influenced by extraction processes. This study was aimed to examine phenolic composition and biological activities of pomegranate peel 70% ethanolic extract and its fractions (petroleum ether, ethyl acetate, butanol and water) obtained by liquid/liquid extractions ...
- DOI:
- 10.1016/j.indcrop.2018.01.031
- https://doi.org/10.1016/j.indcrop.2018.01.031
- Author:
- Joice Guileine Nkuimi Wandjou; Serena Mevi; Gianni Sagratini; Sauro Vittori; Stefano Dall’Acqua; Giovanni Caprioli; Giulio Lupidi; Giacomo Mombelli; Sabrina Arpini; Pietro Allegrini; Francisco Les; Víctor López; Filippo Maggi
- Source:
- Plants 2019 v.9 no.1 pp. -
- ISSN:
- 2223-7747
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Malus domestica; acetylcholinesterase; alpha-glucosidase; amine oxidase (flavin-containing); antioxidant activity; antioxidants; apples; bioactive compounds; dietary supplements; enzyme inhibition; high performance liquid chromatography; inhibitory concentration 50; mass spectrometry; mountains; phytochemicals; triterpenoids; Italy
- Abstract:
- ... This study was undertaken to evaluate the nutraceutical potential of the Mela Rosa dei Monti Sibillini (MR), an ancient apple variety of the Sibillini Mountains, central Italy. The chemical profile of the apple’s polyphenolic-rich extract (MRE) obtained from first- and second-choice samples using the Amberlite® XAD7HP resin was analyzed by High Performance Liquid Chromatography with Diode-Array an ...
- DOI:
- 10.3390/plants9010009
- https://doi.org/10.3390/plants9010009
25. Antioxidant capacity and α-glucosidase inhibitory activity of leaf extracts from ten ramie cultivars
- Author:
- Qin Wang; Muzammal Rehman; Dingxiang Peng; Lijun Liu
- Source:
- Industrial crops and products 2018 v.122 pp. 430-437
- ISSN:
- 0926-6690
- Subject:
- Boehmeria nivea; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; byproducts; chlorogenic acid; cultivars; enzyme inhibition; fabrics; hypoglycemic agents; in vitro studies; ionization; leaf extracts; leaves; mass spectrometry; medicinal properties; phenolic compounds; planting; principal component analysis; ramie; raw materials; rutin; ultra-performance liquid chromatography; China
- Abstract:
- ... Ramie (Boehmeria nivea L. Gaud) is widely cultivated as a raw material for producing natural textiles due to its fine and strong fibers. Ramie leaves are by-products and rich in bioactive compounds that contribute to the medicinal properties of its extracts. This study was conducted to identify the phenolic compounds and evaluate the antioxidant capacity and α-glucosidase inhibitory activities of ...
- DOI:
- 10.1016/j.indcrop.2018.06.020
- https://doi.org/10.1016/j.indcrop.2018.06.020
- Author:
- Corneliu Tanase; Andrei Mocan; Sanda Coșarcă; Alexandru Gavan; Alexandru Nicolescu; Ana-Maria Gheldiu; Dan C. Vodnar; Daniela-Lucia Muntean; Ovidiu Crișan
- Source:
- Antioxidants 2019 v.8 no.9 pp. -
- ISSN:
- 2076-3921
- Subject:
- Candida; Escherichia coli; Fagus sylvatica; Pseudomonas aeruginosa; Salmonella Typhimurium; Staphylococcus aureus; alpha-glucosidase; antioxidant activity; antioxidants; bark; bark extracts; bioactive compounds; catechin; chemical constituents of plants; chlorogenic acid; enzyme activity; epicatechin; experimental design; ferulic acid; functional properties; gallic acid; in vitro studies; isoquercitrin; microwave treatment; polyphenols; protocatechuic acid; solvents; vanillic acid
- Abstract:
- ... The present study aimed, on the one hand, to improve the yield of microwave assisted extraction (MAE) of polyphenols from beech bark by using a design of experiments (DoE) approach. On the other hand, beech bark extracts (BBE) were characterized in terms of their phytochemical profile and evaluated for biological potential (antioxidant, antibacterial, antifungal, antimutagen, anti-α-glucosid ...
- DOI:
- 10.3390/antiox8090417
- PubMed:
- 31546945
- PubMed Central:
- PMC6769934
- https://doi.org/10.3390/antiox8090417
- Author:
- Antonio Vega-Gálvez; Jacqueline Poblete; Issis Quispe-Fuentes; Elsa Uribe; Cristina Bilbao-Sainz; Alexis Pastén
- Source:
- Journal of food measurement & characterization 2019 v.13 no.3 pp. 1980-1990
- ISSN:
- 2193-4126
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Vasconcellea pubescens; alpha-glucosidase; antioxidant activity; antioxidants; ascorbic acid; beta-carotene; bioactive compounds; dose response; enzyme activity; enzyme inhibition; flavonoids; freeze drying; inhibitory concentration 50; processing time; proximate composition; solar drying; vacuum drying
- Abstract:
- ... Chilean papaya slices were dried using different technologies to evaluate the effect of the different technologies on drying kinetics, bioactive compounds and biological activities. Five techniques were used: freeze drying (FD), vacuum drying (VD), solar drying (SD), convective drying (CD) and infrared drying (IRD). Fresh and dried samples were evaluated in terms of proximate composition, phenolic ...
- DOI:
- 10.1007/s11694-019-00117-4
- https://doi.org/10.1007/s11694-019-00117-4
- Author:
- Monica R. Loizzo; Maurizio Bruno; Michele Balzano; Alessandra Giardinieri; Deborah Pacetti; Natale G. Frega; Vincenzo Sicari; Mariarosaria Leporini; Rosa Tundis
- Source:
- European journal of lipid science and technology 2019 v.121 no.1 pp. e1800283
- ISSN:
- 1438-7697
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Opuntia ficus-indica; acarbose; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; beta-carotene; bioactive compounds; bleaching; byproducts; cactus pears; enzyme inhibition; fatty acid composition; food preparation; fruits; functional foods; gamma-tocopherol; glycemic effect; inhibitory concentration 50; linoleic acid; oleic acid; polyunsaturated fatty acids; seed oils; solid phase extraction; ultrasonic treatment; vegetables; Italy; Sicily
- Abstract:
- ... This study investigates the seed oils obtained from two different varieties of Opuntia ficus‐indica (Sanguigna and Surfarina) growing in Sicily, Italy. Soxhlet and ultrasound‐assisted extraction procedures are used to obtain the seed oils. The fatty acid profile, γ‐tocopherols, carotenoid content, and the bioactivity in terms of the antioxidant effects (using ABTS, DPPH, FRAP, and β‐carotene bleac ...
- DOI:
- 10.1002/ejlt.201800283
- https://doi.org/10.1002/ejlt.201800283
- Author:
- Olajumoke Arinola Oyebode; Ochuko Lucky Erukainure; Collins Ibeji; Neil Anthony Koorbanally; Md. Shahidul Islam
- Source:
- Journal of food biochemistry 2019 v.43 no.8 pp. e12930
- ISSN:
- 0145-8884
- Subject:
- Crassocephalum rubens; absorption; alpha-glucosidase; antioxidant activity; antioxidants; binding capacity; bioactive compounds; carboxylic ester hydrolases; catalase; enzyme activity; enzyme inhibition; glucose; green leafy vegetables; intestines; lactones; liquid chromatography; mass spectrometry; muscles; noninsulin-dependent diabetes mellitus; oxidative toxicity; rats; synergism; tissues; Africa
- Abstract:
- ... Crassocephalum rubens falls under the wild edible, under‐cultivated traditional leafy vegetables (TLV) in Africa; it is used by locals in managing diabetes mellitus among other diseases. This study investigated the in vitro, ex vivo antioxidant and antidiabetic potentials of different extracts of C. rubens. The ameliorative effects of the extracts on Fe²⁺‐induced oxidative injury was investigated ...
- DOI:
- 10.1111/jfbc.12930
- https://doi.org/10.1111/jfbc.12930
- Author:
- Ashish Christopher; Dipayan Sarkar; Steve Zwinger; Kalidas Shetty
- Source:
- Journal of ethnic foods 2018 v.5 no.1 pp. 66-74
- ISSN:
- 2352-619X
- Subject:
- Triticum turgidum subsp. dicoccon; alpha-amylase; alpha-glucosidase; amino acids; antioxidant activity; antioxidants; bioactive compounds; chronic diseases; cultivars; enzyme inhibition; glycemic effect; hyperglycemia; immigration; in vitro studies; milling; minerals; noninsulin-dependent diabetes mellitus; nutrient content; oxidative stress; phenolic acids; protein content; tetraploidy; traditional foods; wheat; North Dakota; Russia
- Abstract:
- ... Ancient grains with ethnic food origins are gaining renewed interest in contemporary food design due to its balanced nutritional profiles and health benefits. The “North Dakota Common Emmer Wheat” (Triticum dicoccum), a tetraploid species, had ethnic origins with German immigrants from Russia migrating to North Dakota in late 19th century. Targeting such grains with ethnic origins that are rich in ...
- DOI:
- 10.1016/j.jef.2018.01.002
- https://doi.org/10.1016/j.jef.2018.01.002
- Author:
- Graziela Bragueto Escher; Lorena do Carmo Cardoso Borges; Jânio Sousa Santos; Thiago Mendanha Cruz; Mariza Boscacci Marques; Mariana Araújo Vieira do Carmo; Luciana Azevedo; Marianna M. Furtado; Anderson S. Sant’Ana; Mingchun Wen; Liang Zhang; Daniel Granato
- Source:
- Antioxidants 2019 v.8 no.11 pp. -
- ISSN:
- 2076-3921
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Calendula officinalis; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; brain; copper; cytotoxicity; edible flowers; electrospray ionization mass spectrometry; enzyme activity; enzyme inhibition; erythrocytes; ethanol; flavonoids; freeze drying; humans; ingredients; iron; lipid peroxidation; liquid chromatography; mechanical stress; models; neoplasm cells; phenolic acids; sensory evaluation; taste; yogurt
- Abstract:
- ... Edible flowers have been used as ingredients because of their biological activities, taste, and overall appearance. This research was aimed to characterize the chemical composition and in vitro antioxidant activity of the marigold flower (Calendula officinalis L.) extracted with different proportions of water and ethyl alcohol, and the lyophilized extract with higher content of antioxidant compoun ...
- DOI:
- 10.3390/antiox8110559
- PubMed:
- 31731768
- PubMed Central:
- PMC6912323
- https://doi.org/10.3390/antiox8110559
- Author:
- Sengul Uysal; Zaahira Aumeeruddy-Elalfi; Gokhan Zengin; Abdurrahman Aktumsek; Andrei Mocan; Luisa Custodio; Nuno R. Neng; José M.F. Nogueira; Ana Ćirić; Jasmina Glamočlija; Marina Soković; M.Fawzi Mahomoodally
- Source:
- Industrial crops and products 2018 v.113 pp. 422-428
- ISSN:
- 0926-6690
- Subject:
- Ballota; aerial parts; alpha-amylase; alpha-glucosidase; antimicrobial properties; antioxidant activity; antioxidants; bacteria; bioactive compounds; caffeic acid; catechin; epicatechin; ferulic acid; fungi; health promotion; high performance liquid chromatography; medicinal plants; methanol; phytopharmaceuticals; quercetin; rutin; solvents; syringic acid; therapeutics; traditional medicine; vanillic acid; Turkey (country)
- Abstract:
- ... Ballota macrodonta Boiss. et Balansa., is a traditionally used endemic medicinal plant used to manage a plethora of diseases in Turkey. Nonetheless, few studies have endeavoured to highlight its therapeutic potential and its phytochemical profile. We hypothesized that B. macrodonta would possess multi-pharmacological propensities and bioactive compounds that would justify its use as a folk remedy. ...
- DOI:
- 10.1016/j.indcrop.2018.01.001
- https://doi.org/10.1016/j.indcrop.2018.01.001
- Author:
- Sengul Uysal; Asli Ugurlu; Gokhan Zengin; Mehmet Cengiz Baloglu; Yasemin Celik Altunoglu; Adriano Mollica; Luisa Custodio; Nuno R. Neng; José M.F. Nogueira; M. Fawzi Mahomoodally
- Source:
- Food and chemical toxicology 2018 v.111 pp. 525-536
- ISSN:
- 0278-6915
- Subject:
- Bidens tripartita; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; cell lines; cell viability; chlorogenic acid; computer simulation; cytotoxicity; enzyme inhibition; epicatechin; ethyl acetate; high performance liquid chromatography; hydrogen bonding; methanol; neoplasm cells; neoplasms; plasmids; toxicology; viability assays
- Abstract:
- ... Bidens tripartita L. is a traditional phyto-remedy used in several countries, yet there is still a paucity of data on its biological potential. We aimed to provide new insights on the pharmacological potential of extracts prepared from B. tripartita via highlighting its antioxidant, key enzymes inhibitory potency, and DNA protecting effects. Phytochemical profile was established using High-Perform ...
- DOI:
- 10.1016/j.fct.2017.11.058
- https://doi.org/10.1016/j.fct.2017.11.058
- Author:
- S. Fettach; H.N. Mrabti; K. Sayah; A. Bouyahya; N. Salhi; Y. Cherrah; F.M. El Abbes
- Source:
- South African journal of botany 2019 v.125 pp. 381-385
- ISSN:
- 0254-6299
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Ajuga iva; acute toxicity; aerial parts; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; blood glucose; carbohydrate metabolism; drugs; females; flavonoids; glycemic effect; hyperglycemia; lethal dose 50; mechanism of action; methanol; mice; noninsulin-dependent diabetes mellitus; oligosaccharides
- Abstract:
- ... The management of blood glucose level is the hallmark in the treatment of type 2 diabetes, and this may be achieved through the inhibition of the digestive enzymes involved in carbohydrate metabolism. The aim of this work is the investigation of phenolic compounds content, antioxidant activity and for the first time, the in vitro anti-hyperglycemic potential of aerial part of Ajuga iva Schreber ex ...
- DOI:
- 10.1016/j.sajb.2019.08.010
- https://doi.org/10.1016/j.sajb.2019.08.010
- Author:
- Nausheen Nazir; Muhammad Zahoor; Mohammad Nisar; Imran Khan; Nasiara Karim; Heba Abdel-Halim; Akhtar Ali
- Source:
- BMC complementary and alternative medicine 2018 v.18 no.1 pp. 332
- ISSN:
- 1472-6882
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Elaeagnus umbellata; acarbose; active sites; adults; alanine transaminase; alkaline phosphatase; alpha-amylase; alpha-glucosidase; alternative medicine; animal disease models; antioxidant activity; antioxidants; aspartate transaminase; binding sites; bioactive compounds; blood serum; butanol; chemical constituents of plants; chloroform; cholesterol; computer simulation; ethyl acetate; free radicals; fruits; glucose; glycemic effect; high performance liquid chromatography; hyperglycemia; inhibitory concentration 50; laboratory animals; low density lipoprotein; noninsulin-dependent diabetes mellitus; oxidative stress; plant extracts; rats; triacylglycerols
- Abstract:
- ... BACKGROUND: The fruit of Elaeagnus umbellata has high medicinal values and is an excellent source of phytochemicals. This study was aimed to evaluate the antioxidant, enzyme inhibitory and antidiabetic potential of Elaeagnus umbellata. METHODS: The antioxidant potential of the crude extract and subfractions of E. umbellata fruit were determined using DPPH (2, 20-diphenyl-1-picrylhydrazyl) and ABTS ...
- DOI:
- 10.1186/s12906-018-2381-8
- PubMed:
- 30545352
- PubMed Central:
- PMC6293591
- https://doi.org/10.1186/s12906-018-2381-8
- Author:
- Habib Mosbah; Hanen Louati; Mohamed Ali Boujbiha; Hassiba Chahdoura; Mejdi Snoussi; Guido Flamini; Roberta Ascrizzi; Ali Bouslema; Lotfi Achour; Boulbaba Selmi
- Source:
- Industrial crops and products 2018 v.112 pp. 521-531
- ISSN:
- 0926-6690
- Subject:
- Acca sellowiana; DNA; acetic acid; acute toxicity; alpha-amylase; alpha-glucosidase; analgesic effect; antifungal properties; antioxidant activity; antioxidants; aspirin; beta-caryophyllene; bioactive compounds; body weight; cations; chemical constituents of plants; diabetes; free radicals; gas chromatography-mass spectrometry; headspace analysis; in vitro studies; inhibitory concentration 50; leaf extracts; leaves; limonene; lipid peroxidation; mice; rats; solid phase microextraction; writhing test; Tunisia
- Abstract:
- ... In this study, headspace solid-phase microextraction coupled to GC–MS was applied to identify the volatile bioactive compounds in the leaves of Feijoa sellowiana growing in Tunisia. Thirty-one components were identified, representing 99.9% of the total volatiles. The major constituents were limonene (36.2%), β-caryophyllene (27.8%), aromadendrene (12.5%), and α-copaene (6.6%). Also, the F. sellowi ...
- DOI:
- 10.1016/j.indcrop.2017.12.051
- https://doi.org/10.1016/j.indcrop.2017.12.051
- Author:
- Saima Khan; Mamona Nazir; Naheed Raiz; Muhammad Saleem; Gokhan Zengin; Gazala Fazal; Hammad Saleem; Mahreen Mukhtar; Muhammad Imran Tousif; Rasool Baksh Tareen; Hassan H. Abdallah; Fawzi M. Mahomoodally
- Source:
- Industrial crops and products 2019 v.131 pp. 117-124
- ISSN:
- 0926-6690
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Caragana; alkaloids; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; computer simulation; coumarin; enzyme inhibition; ethyl acetate; flavonoids; hexane; industrial applications; liquid chromatography; mass spectrometry; medicinal properties; methanol; secondary metabolites
- Abstract:
- ... Plant from Caragana genus have interesting potential in folklore medicines and have been explored for various pharmacological activities. The aim of this study was to probe into the chemical and biological effects of different extracts of Caragana ambigua Stocks (Fabaceae). Total phenolic and total flavonoids contents were determined using standard spectrophotometric methods, whereas, the secondar ...
- DOI:
- 10.1016/j.indcrop.2019.01.044
- https://doi.org/10.1016/j.indcrop.2019.01.044
- Author:
- Teresa Herrera; Yolanda Aguilera; Miguel Rebollo-Hernanz; Elena Bravo; Vanesa Benítez; Nuria Martínez-Sáez; Silvia M. Arribas; María Dolores del Castillo; María A. Martín-Cabrejas
- Source:
- Lebensmittel-Wissenschaft + Technologie 2018 v.89 pp. 65-73
- ISSN:
- 0023-6438
- Subject:
- green tea; Melissa officinalis; chamomile; 2,2-diphenyl-1-picrylhydrazyl; alpha-glucosidase; health promotion; medicinal plants; carboxylic ester hydrolases; melatonin; dietary nutrient sources; bioactive compounds; digestive enzymes; flavonoids; antioxidant activity; antioxidants; beverages; Europe; United States
- Abstract:
- ... The consumption of teas and herbal infusions has increased in Europe and the USA in recent years. The goal of this work was to provide new knowledge on the contents of melatonin and other bioactive non-nutrient compounds of nineteen highly consumed herbal infusions. Melatonin was previously assessed in some medicinal plants alcoholic extracts but not described in herbal aqueous infusions as we rep ...
- DOI:
- 10.1016/j.lwt.2017.10.031
- https://doi.org/10.1016/j.lwt.2017.10.031
- Author:
- Dian Herawati; Puspo Edi Giriwono; Fitriya Nur Annisa Dewi; Takehiro Kashiwagi; Nuri Andarwulan
- Source:
- International journal of food properties 2019 v.22 no.1 pp. 994-1010
- ISSN:
- 1094-2912
- Subject:
- Coffea canephora; alpha-glucosidase; antioxidants; bioactive compounds; bioactive properties; brewing; caffeine; chlorogenic acid; coffee (beverage); coffee beans; enzyme inhibition; functional foods; grinding; liquid chromatography; mass spectrometry; noninsulin-dependent diabetes mellitus; nuclear magnetic resonance spectroscopy
- Abstract:
- ... The objective of this study was to separate and identify the bioactive compounds in the Robusta coffee brew. The coffee brew showed significant potential for antioxidant, anti-α-glucosidase, and antiglycation activities, as well as effectiveness in managing type 2 diabetes mellitus (T2DM). Indonesian Lampung Robusta coffee beans were roasted at the first crack level, followed by grinding and brewi ...
- DOI:
- 10.1080/10942912.2019.1622562
- https://doi.org/10.1080/10942912.2019.1622562
- Author:
- Saravanan Shanmugam; Isla Alcântara Gomes; Marina Denadai; Bruno dos Santos Lima; Adriano Antunes de Souza Araújo; Narendra Narain; Maria Terezinha Santos Leite Neta; Mairim Russo Serafini; Lucindo José Quintans-Júnior; Parimelazhagan Thangaraj
- Source:
- Food research international 2018 v.108 pp. 611-620
- ISSN:
- 0963-9969
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Passiflora; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; cinnamic acid; crude protein; enzyme inhibition; epicatechin; ferulic acid; fruit pulp; fruits; functional foods; glucose; humans; inhibitory concentration 50; noninsulin-dependent diabetes mellitus; p-coumaric acid; polyphenols; protocatechuic acid; raw fruit; tandem mass spectrometry; vanillic acid
- Abstract:
- ... The diabetic key enzymes inhibition, nutritional, antioxidant activity and bioactive compounds identification of Passiflora subpeltata fruit pulp were investigated. Fifteen polyphenolic compounds including protocatechuic acid, ferulic acid, vanillic acid, epicatechin, p-coumaric acid, cinnamic acid, eriodictyol and quercetin-3-glucoside were identified in the pulp of this species by using UHPLC-Qq ...
- DOI:
- 10.1016/j.foodres.2018.04.006
- https://doi.org/10.1016/j.foodres.2018.04.006
- Author:
- Zeineb Mzoughi; Hassiba Chahdoura; Yasmine Chakroun; Montaña Cámara; Virginia Fernández-Ruiz; Patricia Morales; Habib Mosbah; Guido Flamini; Mejdi Snoussi; Hatem Majdoub
- Source:
- Food research international 2018 pp. -
- ISSN:
- 0963-9969
- Subject:
- Beta vulgaris subsp. vulgaris; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; calcium; carbohydrates; chard; chemical constituents of plants; dietary fiber; enzyme activity; enzyme inhibition; ethanol; iron; leaf extracts; leaves; magnesium; odors; proximate composition; rosmarinic acid; sesquiterpenoids; sodium; volatile compounds
- Abstract:
- ... Nutritional, soluble carbohydrates and aroma volatile profiles of Tunisian wild Swiss chard leaves (Beta vulgaris L. var. cicla) have been characterized. The chemical composition of an ethanol chard leaves extract, as well as its in vitro antioxidant, α-amylase and α-glucosidase inhibition activities were carefully evaluated. The results of the proximate composition showed that total carbohydrate ...
- DOI:
- 10.1016/j.foodres.2018.10.039
- https://doi.org/10.1016/j.foodres.2018.10.039
- Author:
- Ping Hu; Da-Hong Li; Cui-Cui Jia; Quan Liu; Xiao-Fei Wang; Zhan-Lin Li; Hui-Ming Hua
- Source:
- Journal of functional foods 2017 v.35 pp. 236-244
- ISSN:
- 1756-4646
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Vitex negundo; acarbose; alpha-glucosidase; antioxidant activity; antioxidants; ascorbic acid; bioactive compounds; coumarin; functional foods; inhibitory concentration 50; iridoid glycosides; leaves; seeds; China
- Abstract:
- ... Vitex negundo L. var. heterophylla (Franch.) Rehd. is widely accepted as a functional and medicinal food in China because of the presence of bioactive components which improve the physical condition. In the present study, the bioactive constituents, antioxidant, α-glucosidase and DPP-IV inhibitory activities of V. negundo var. heterophylla were investigated. Two new coumarin glycosides, vitexneghe ...
- DOI:
- 10.1016/j.jff.2017.05.047
- https://doi.org/10.1016/j.jff.2017.05.047
- Author:
- Bulent Kirkan; Mehmet Sabih Ozer; Cengiz Sarikurkcu; Mahmut Copuroglu; Mustafa Cengiz; Bektas Tepe
- Source:
- Industrial crops and products 2018 v.115 pp. 1-5
- ISSN:
- 0926-6690
- Subject:
- Papaver somniferum; acarbose; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; byproducts; cholinesterase; enzyme inhibition; gallic acid; high performance liquid chromatography; industry; methanol; phytopharmaceuticals; raw materials; rutin; syringic acid
- Abstract:
- ... Alternative raw materials for designing novel products are gaining interest in the scientific area. The aim of this study is to investigate the antioxidant and enzyme inhibitory activities of the extracts obtained from Papaver somniferum L. stalks as well as the determination of chemical composition. Antioxidant capacity was tested by using different chemical methods including radical scavenging, ...
- DOI:
- 10.1016/j.indcrop.2018.02.023
- https://doi.org/10.1016/j.indcrop.2018.02.023
- Author:
- Gokhan Zengin; Ramazan Ceylan; Jelena Katanić; Adriano Mollica; Abdurrahman Aktumsek; Tatjana Boroja; Sanja Matić; Vladimir Mihailović; Snežana Stanić; Zaahira Aumeeruddy-Elalfi; Mustafa Abdullah Yilmaz; Mohamad Fawzi Mahomoodally
- Source:
- Food and chemical toxicology 2017 v.107 pp. 540-553
- ISSN:
- 0278-6915
- Subject:
- DNA damage; Drosophila melanogaster; acetylcholinesterase; alpha-amylase; alpha-glucosidase; antimicrobial properties; antioxidant activity; antioxidants; bioactive compounds; cholinesterase; diabetes; functional foods; hesperidin; liquid chromatography; malic acid; metabolites; mutagens; phytopharmaceuticals; protocatechuic acid; rosmarinic acid; rutin; tandem mass spectrometry; toxicology
- Abstract:
- ... Methanolic extracts of Moltkia aurea Boiss. (MA) and Moltkia coerulea (Willd.) Lehm. (MC) were investigated for their antioxidant capacity and enzymatic inhibitory potential against acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, and tyrosinase in vitro. MA and MC were also explored for their antimicrobial effect, as well as for their possible genotoxic/antigenotoxic potenti ...
- DOI:
- 10.1016/j.fct.2017.04.004
- https://doi.org/10.1016/j.fct.2017.04.004
- Author:
- Basiru Olaitan Ajiboye; Oluwafemi Adeleke Ojo; Mary Abiola Okesola; Babatunji Emmanuel Oyinloye; Abidemi Paul Kappo
- Source:
- International journal of food properties 2018 v.21 no.1 pp. 1697-1715
- ISSN:
- 1532-2386
- Subject:
- Cnidoscolus aconitifolius; acetylcholinesterase; alpha-glucosidase; amine oxidase (flavin-containing); antioxidant activity; antioxidants; arginase; bioactive compounds; carbohydrate metabolism; chelation; cholinesterase; coumaric acids; enzyme activity; enzyme inhibition; ethyl acetate; hesperidin; high performance liquid chromatography; iron; kaempferol; leaves; protocatechuic acid; rutin
- Abstract:
- ... In this study, the antioxidant, carbohydrate metabolism, cholinergic, monoaminergic, and purinergic enzyme activities of ethyl acetate leaf fraction of Cnidoscolus aconitifolius were evaluated with the high-performance liquid chromatography (HPLC) analysis. The ethyl acetate fraction of the plant leaf was tested for antioxidant properties, key carbohydrate metabolism, cholinergic, monoaminergic, a ...
- DOI:
- 10.1080/10942912.2018.1504787
- https://doi.org/10.1080/10942912.2018.1504787
- Author:
- E.J. Llorent-Martínez; P. Ortega-Barrales; G. Zengin; A. Mocan; M.J. Simirgiotis; R. Ceylan; S. Uysal; A. Aktumsek
- Source:
- Food and chemical toxicology 2017 v.107 pp. 609-619
- ISSN:
- 0278-6915
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Lathyrus cicera; acetylcholinesterase; aerial parts; agricultural land; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; cholinesterase; enzyme inhibition; flavonoids; food industry; functional foods; high performance liquid chromatography; ionization; mass spectrometry; phytopharmaceuticals; screening; toxicology
- Abstract:
- ... The genus Lathyrus has great importance in terms of food and agricultural areas. In this study, the in vitro antioxidant activity (phosphomolybdenum, DPPH, ABTS, FRAP, CUPRAC and metal chelating) and enzyme inhibitory activity evaluation (acetylcholinesterase, butyrylcholinesterase, α-amylase and α-glucosidase) of L. cicera and L. digitatus were investigated, as well as their phytochemical profile ...
- DOI:
- 10.1016/j.fct.2017.03.002
- https://doi.org/10.1016/j.fct.2017.03.002
- Author:
- Luis Daniel Daza; Alice Fujita; Daniel Granato; Carmén Silvia Fávaro-Trindade; Maria Inés Genovese
- Source:
- Food bioscience 2017 v.18 pp. 15-21
- ISSN:
- 2212-4292
- Subject:
- Eugenia dysenterica; Staphylococcus aureus; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; bioactive compounds; ceftriaxone; encapsulation; erythromycin; fruit extracts; functional properties; gum arabic; inulin; powders; proanthocyanidins; spray drying; vancomycin
- Abstract:
- ... Cagaita (Eugenia dysenterica DC.) is an important native Brazilian fruit species with potential health effects associated with its concentration and profile of polyphenols. The aim of this work was to evaluate the total phenolic (TPC), total proanthocyanidins, the antioxidant, antimicrobial, and anti-obesity potential of cagaita extracted, dried and encapsulated powders. Samples were produced with ...
- DOI:
- 10.1016/j.fbio.2017.03.003
- https://doi.org/10.1016/j.fbio.2017.03.003
- Author:
- Lu Zhang; Zong-cai Tu; Xing Xie; Hui Wang; Hao Wang; Zhen-xing Wang; Xiao-mei Sha; Yu Lu
- Source:
- Food chemistry 2017 v.234 pp. 303-313
- ISSN:
- 0308-8146
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Artocarpus heterophyllus; acarbose; alpha-glucosidase; antioxidants; bioactive compounds; byproducts; coumaric acids; flavonoids; glycosides; hypoglycemic agents; jackfruits; phytopharmaceuticals; pulp; seed extracts
- Abstract:
- ... Jackfruit (Artocarpus heterophyllus Lam.) peel is an underutilized by-product in both, the production and processing of jackfruit. This research compared the antioxidant and hypoglycemic potential of jackfruit peel with jackfruit pulp, flake and seed for the first time. The phytochemical profile of peel extract was characterized with HPLC-QTOF-MS/MS. Results revealed that peel extract exhibited th ...
- DOI:
- 10.1016/j.foodchem.2017.05.003
- https://doi.org/10.1016/j.foodchem.2017.05.003
- Author:
- Peiyou Qin; Aichun Wei; Degang Zhao; Yang Yao; Xiushi Yang; Baoqing Dun; Guixing Ren
- Source:
- Food chemistry 2017 v.224 pp. 124-130
- ISSN:
- 0308-8146
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; alpha-glucosidase; antioxidants; bioactive compounds; buckwheat sprouts; isoquercitrin; kaempferol; myo-inositol; quercetin; rutin; sodium bicarbonate
- Abstract:
- ... This study aimed to investigate the effects of different concentrations of sodium bicarbonate (NaHCO3) on the accumulation of flavonoids, total phenolics and d-chiro-inositol (DCI), as well as the antioxidant and α-glucosidase inhibitory activities, in tartary buckwheat sprouts. Treatment with low concentrations of NaHCO3 (0.05, 0.1, and 0.2%) resulted in an increase in flavonoids, total phenolic ...
- DOI:
- 10.1016/j.foodchem.2016.12.059
- https://doi.org/10.1016/j.foodchem.2016.12.059
- Author:
- Ramgopal Mopuri; Muniswamy Ganjayi; Balaji Meriga; Neil Anthony Koorbanally; Md. Shahidul Islam
- Source:
- Yàowù shípǐn fēnxī 2018 v.26 no.1 pp. 201-210
- ISSN:
- 1021-9498
- Subject:
- Ficus carica; acetates; alpha-amylase; alpha-glucosidase; antioxidants; bioactive compounds; butanes; butyrates; drugs; figs; flavonoids; gas chromatography-mass spectrometry; hydroxymethylfurfural; inhibitory concentration 50; leaves; malic acid; metabolic syndrome; models; polyphenols; solvents; stearic acid; triacylglycerol lipase
- Abstract:
- ... The present study aimed to investigate the effects of the various parts of Ficus carica L. (figs) on antioxidant, antidiabetic, and antiobesogenic effects in vitro. Fruit, leaves, and stembark of the F. carica plant were sequentially extracted using organic and inorganic solvents and their total polyphenol and flavonoid contents were estimated. The effects of the extracts on antioxidative, antidia ...
- DOI:
- 10.1016/j.jfda.2017.03.001
- https://doi.org/10.1016/j.jfda.2017.03.001
- Author:
- Yan Bai; Yan Xu; Jiawei Chang; Xiaoxue Wang; Yunli Zhao; Zhiguo Yu
- Source:
- Journal of functional foods 2016 v.25 pp. 314-322
- ISSN:
- 1756-4646
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Vigna radiata; alpha-glucosidase; antioxidant activity; antioxidants; ascorbic acid; bioactive compounds; byproducts; glycemic effect; hypoglycemic agents; isoflavones; leaves; lignans; median effective concentration; mung beans; nuclear magnetic resonance spectroscopy; seeds; stems
- Abstract:
- ... After the harvest of the seeds of mung beans (Vigna radiata L.) (MB), a significant quantity of by-products (stems, leaves) is generated. The aim of this study was to isolate key bioactive components from MB with antioxidant and antidiabetic activities. Two new isoflavones, thirteen known flavonoids, and seven known lignans were obtained. Their structures were identified by extensive 1D and 2D NMR ...
- DOI:
- 10.1016/j.jff.2016.06.009
- https://doi.org/10.1016/j.jff.2016.06.009
- Author:
- Priyatharini Ambigaipalan; Adriano Costa de Camargo; Fereidoon Shahidi
- Source:
- Food chemistry 2017 v.221 pp. 1883-1894
- ISSN:
- 0308-8146
- Subject:
- anthocyanins; DNA damage; hydroxyl radicals; juices; pomegranates; copper; proanthocyanidins; seeds; alpha-glucosidase; low density lipoprotein cholesterol; carboxylic ester hydrolases; peroxidation; tannins; bioactive compounds; hydrolysis; chelation
- Abstract:
- ... Phenolics from free and hydrolyzed fractions of pomegranate juice (PJ) and seeds (PS) were evaluated. In general, total phenolic contents and scavenging of ABTS+, DPPH and hydroxyl radicals, as well as metal chelation of the soluble fraction from PS, were higher than those for PJ. Insoluble-bound phenolics from PS accounted for up to 27% of total scavenging capacity (free+esterified+insoluble-boun ...
- DOI:
- 10.1016/j.foodchem.2016.10.058
- https://doi.org/10.1016/j.foodchem.2016.10.058
- Author:
- Gokhan Zengin; Zaahira Aumeeruddy-Elalfi; Adriano Mollica; Mustafa Abdullah Yilmaz; Mohamad Fawzi Mahomoodally
- Source:
- Phytomedicine 2017 pp. -
- ISSN:
- 0944-7113
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Halimione portulacoides; Salicornia europaea; acetylcholinesterase; alpha-amylase; alpha-glucosidase; antioxidants; bioactive compounds; cholinesterase; drugs; enzyme inhibition; ethyl acetate; flavonoids; free radicals; halophytes; liquids; methanol; molecular models; p-coumaric acid; phytopharmaceuticals; quinic acid; reducing agents; tandem mass spectrometry
- Abstract:
- ... Halophytes are considered as valuable sources of traditional drugs in different countries.The present study aimed to evaluate biological and chemical fingerprints of three halophytes (Arthrocnemum macrostachyum (Moric.) C, Koch, Halimione portulacoides (L.) Aellen and Salicornia europaea L.).The antioxidant and enzymatic inhibitory potential (acetylcholinesterase, butyrylcholinesterase, α-amylase, ...
- DOI:
- 10.1016/j.phymed.2017.10.017
- https://doi.org/10.1016/j.phymed.2017.10.017
54. In vitro assessment of the antihyperglycemic and antioxidant properties of araçá, butiá and pitanga
- Author:
- Juliana Vinholes; Graciele Lemos; Rosa Lia Barbieri; Rodrigo C. Franzon; Márcia Vizzotto
- Source:
- Food bioscience 2017 v.19 pp. 92-100
- ISSN:
- 2212-4292
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Butia odorata; Eugenia uniflora; Psidium cattleyanum; alpha-glucosidase; anthocyanins; antioxidant activity; antioxidants; bioactive compounds; blood glucose; carotenoids; ethanol; free radicals; fruits; glycemic effect; in vitro studies; inhibitory concentration 50; nitric oxide; nonreducing sugars; patients; principal component analysis; reducing sugars
- Abstract:
- ... Native fruits have been known as a great source of bioactive compounds with potential biological effects. The aim of this study was to investigate the α-glucosidase inhibition and antioxidant activities of araçá (Psidium cattleianum Sabine), butiá (Butia odorata (Barb. Rodr.) Noblick) and pitanga (Eugenia uniflora L.) and relate their chemical composition with the observed biological activity. Sam ...
- DOI:
- 10.1016/j.fbio.2017.06.005
- https://doi.org/10.1016/j.fbio.2017.06.005
- Author:
- E. J. Llorent-Martínez; P. Ortega-Barrales; G. Zengin; S. Uysal; R. Ceylan; G. O. Guler; A. Mocan; A. Aktumsek
- Source:
- RSC advances 2016 v.6 no.92 pp. 88996-89006
- ISSN:
- 2046-2069
- Subject:
- 2,2-diphenyl-1-picrylhydrazyl; Lathyrus pratensis; acetylcholinesterase; aerial parts; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; beta-carotene; bioactive compounds; bleaching; cholinesterase; enzyme inhibition; flavonoids; food industry; high performance liquid chromatography; industrial applications; ionization; mass spectrometry; methanol; phytopharmaceuticals; saponins; traditional medicine; wild plants
- Abstract:
- ... Different wild plants commonly used in folk medicine, such as different species from the genus Lathyrus, may represent new sources of biologically active compounds. Hence, a study of the composition and (bio)chemical behaviour of extracts from these plants may provide valuable information. To evaluate the phytochemical profile, and the enzyme inhibition and antioxidant activities of the aerial par ...
- DOI:
- 10.1039/c6ra17170b
- https://doi.org/10.1039/c6ra17170b
- Author:
- Tingting Wang; Xia Li; Bin Zhou; Hongfa Li; Jie Zeng; Wenyuan Gao
- Source:
- Journal of functional foods 2015 v.13 pp. 276-288
- ISSN:
- 1756-4646
- Subject:
- Pyrus ussuriensis; alpha-glucosidase; animal disease models; anti-inflammatory activity; antioxidants; bioactive compounds; ears; edema; flavonoids; glycemic effect; high performance liquid chromatography; mass spectrometry; mice; noninsulin-dependent diabetes mellitus; pears; phenolic acids; polyphenols; principal component analysis; pulp; triterpenoids
- Abstract:
- ... Total phenolic acids, total flavonoids, total triterpenes contents, and eleven monomeric compounds, derived from eight different pears' peel and pulp, were qualitatively and quantitively profiled utilizing HPLC and HPLC-MS. All the chemical components found in the peel were approximately 2 to 18 folds concentrated than those in the pulp. Their antioxidant (reducing power and 2, 2-diphenyl-1-picryl ...
- DOI:
- 10.1016/j.jff.2014.12.049
- https://doi.org/10.1016/j.jff.2014.12.049
- Author:
- Shyh-Shyun Huang; Shan-Yu Su; Jui-Shu Chang; Hung-Jen Lin; Wen-Tzu Wu; Jeng-Shyan Deng; Guan-Jhong Huang
- Source:
- Botanical studies 2016 v.57 no.1 pp. 38
- ISSN:
- 1999-3110
- Subject:
- Glycine max; Glycine tabacina; Western blotting; aldehyde reductase; alpha-glucosidase; anti-inflammatory activity; antioxidant activity; antioxidants; bioactive compounds; daidzein; foods; genistein; glycemic effect; high performance liquid chromatography; inducible nitric oxide synthase; inhibitory concentration 50; lipopolysaccharides; macrophages; mice; nitric oxide; polyphenols; prostaglandin synthase; protein synthesis
- Abstract:
- ... BACKGROUND: The aim of this study was to examine the possible antioxidant, anti-inflammatory, and antidiabetic effects of the aqueous extracts from three Glycine species. In HPLC analysis, the chromatograms of three Glycine species were established. Flavonoid-related compounds might be important bioactive compounds in Glycine species. RESULTS: The results showed that the aqueous extract of Glycine ...
- DOI:
- 10.1186/s40529-016-0153-7
- PubMed:
- 28597448
- PubMed Central:
- PMC5432927
- https://doi.org/10.1186/s40529-016-0153-7
- Author:
- Jânio Sousa Santos; Carolina Turnes Pasini Deolindo; Luis Antônio Esmerino; Maria Inés Genovese; Alice Fujita; Mariza Boscacci Marques; Neiva Deliberali Rosso; Heitor Daguer; Andressa Camargo Valese; Daniel Granato
- Source:
- Food research international 2016 v.89 pp. 476-487
- ISSN:
- 0963-9969
- Subject:
- Aspalathus linearis; Candida albicans; Escherichia coli; Staphylococcus aureus; alpha-amylase; alpha-glucosidase; anti-infective properties; antioxidant activity; antioxidants; bioactive compounds; erythrocytes; flavonols; functional properties; hemolysis; humans; inhibitory concentration 50; isoquercitrin; luteolin; salicylic acid; tannins; temperature
- Abstract:
- ... This work was aimed at assessing the time-temperature effects on the phenolic compounds and in vitro functional properties of aqueous extracts from red rooibos (Aspalathus linearis). The major phenolic composition (tannins, flavonoids, flavonols, ortho-diphenols, total phenolic content), antioxidant (ABTS and DPPH) and reducing capacities (FRAP and total reducing capacity), antimicrobial effects a ...
- DOI:
- 10.1016/j.foodres.2016.08.041
- https://doi.org/10.1016/j.foodres.2016.08.041