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1. 3D-printed oxygen-releasing scaffolds improve bone regeneration in mice

Author:
Ashley L. Farris; Dennis Lambrechts; Yuxiao Zhou; Nicholas Y. Zhang; Naboneeta Sarkar; Megan C. Moorer; Alexandra N. Rindone; Ethan L. Nyberg; Alexander Perdomo-Pantoja; S.J. Burris; Kendall Free; Timothy F. Witham; Ryan C. Riddle; Warren L. Grayson
Source:
Biomaterials 2022 v.280 pp. 121318
ISSN:
0142-9612
Subject:
antioxidants; biocompatible materials; biodegradability; bone formation; bones; extracellular matrix; humans; hyperoxia; hypoxia; mice; osteopontin; oxygen; polyvinyl alcohol; therapeutics; tissue repair; toxicity
Abstract:
... Low oxygen (O₂) diffusion into large tissue engineered scaffolds hinders the therapeutic efficacy of transplanted cells. To overcome this, we previously studied hollow, hyperbarically-loaded microtanks (μtanks) to serve as O₂ reservoirs. To adapt these for bone regeneration, we fabricated biodegradable μtanks from polyvinyl alcohol and poly (lactic-co-glycolic acid) and embedded them to form 3D-pr ...
DOI:
10.1016/j.biomaterials.2021.121318

2. 4,4′-Dimethoxychalcone protects the skin from AAPH-induced senescence and UVB-induced photoaging by activating autophagy

Author:
Yanpei Gu; Jianxin Han; Fan Xue; Hongrui Xiao; Lihuan Chen; Zhenlei Zhao; Ying Zhang
Source:
Food & function 2022 v.13 no.7 pp. 4114-4129
ISSN:
2042-650X
Subject:
Angelica sinensis; acetylcysteine; antioxidants; autophagy; cell senescence; flavonoids; longevity; mitogen-activated protein kinase; models; oxidative stress; phosphorylation; photoaging; signal transduction; therapeutics
Abstract:
... Aging can lead to the occurrence of many degenerative diseases, and the most intuitive consequences are mainly manifested on the skin, which is affected by both endogenous and exogenous aging factors and can be used as an ideal model organ for studying aging. 4,4′-Dimethoxychalcone (DMC), a natural flavonoid compound from Angelica sinensis, has been proven to prolong the lifespan of multiple speci ...
DOI:
10.1039/d1fo04130d

3. A Cross-Sectional Study of Association between Plasma Selenium Levels and the Prevalence of Osteoarthritis: Data from the Xiangya Osteoarthritis Study

Author:
N. Wang; M. Xie; G. Lei; C. Zeng; T. Yang; Z. Yang; Y. Wang; J. Li; J. Wei; Jian Tian; Tuo Yang
Source:
journal of nutrition, health & aging 2022 v.26 no.2 pp. 197-202
ISSN:
1279-7707
Subject:
antioxidants; cartilage; confidence interval; cross-sectional studies; dose response; hips; inflammation; nutrition; osteoarthritis; oxidative stress; pathogenesis; radiography; selenium; spectroscopy; China
Abstract:
... OBJECTIVES: Selenium plays an indispensable role in antioxidant and antiinflammation processes. Oxidative stress and inflammation have been hypothesized to be involved in the pathogenesis of cartilage degeneration. We sought to examine the association between plasma selenium levels and the prevalence of radiographic osteoarthritis (ROA). DESIGN: A population-based cross-sectional study. SETTING AN ...
DOI:
10.1007/s12603-022-1739-2

4. A Descriptive Chemical Composition of Concentrated Bud Macerates through an Optimized SPE-HPLC-UV-MS2 Method—Application to Alnus glutinosa, Ribes nigrum, Rosa canina, Rosmarinus officinalis and Tilia tomentosa

Author:
Thomas Charpentier; Séverine Boisard; Anne-Marie Le Ray; Dimitri Bréard; Amélie Chabrier; Hélène Esselin; David Guilet; Christophe Ripoll; Pascal Richomme
Source:
Plants 2022 v.11 no.2 pp. -
ISSN:
2223-7747
Subject:
Alnus glutinosa; Ribes nigrum; Rosa canina; Rosmarinus officinalis; Tilia tomentosa; antioxidants; chemical composition; ethanol; glycerol; glycosylation; high performance liquid chromatography; maceration; meristems; nucleosides; quality control; rutin; solid phase extraction; solvents
Abstract:
... Concentrated bud macerates (CBMs) are obtained from meristematic tissues such as buds and young shoots by maceration in a solvent composed of glycerin, water and ethanol (1/1/1/, v/v). Their traditional utilization in gemmotherapy has gained interest in the past years, and the knowledge of their chemical characterization can provide commercial arguments, particularly to secure their quality contro ...
DOI:
10.3390/plants11020144

5. A Halochromic Film Containing Plinia cauliflora Peel Anthocyanins Loaded into a Cashew Gum Polysaccharide-Polyvinyl Alcohol Matrix

Author:
Bruna M. Miranda; Mauricio V. Cruz; Ivan T. N. de Campos; Kátia F. Fernandes; Flávio A. Silva
Source:
Waste and biomass valorization 2022 v.13 no.5 pp. 2565-2574
ISSN:
1877-2641
Subject:
Plinia cauliflora; alcohols; anthocyanins; antioxidant activity; antioxidants; biomass; cashew gum; cell walls; chromatography; color; cyanidin; delphinidin; endo-1,4-beta-glucanase; enzymatic treatment; fractionation; pH; polygalacturonase; polyvinyl alcohol; solvents; temperature; wastes
Abstract:
... This study reports the extraction of anthocyanins from P. cauliflora peels, its partial characterization and the inclusion into a halochromic film based on cashew gum polysaccharide and polyvinyl alcohol (CGP/PVA). Three kinds of extractions were performed: The classic acidic-alcoholic solvent method; enzymatic method with the cell wall degrading enzymes (cellulase and pectinase) and the combinati ...
DOI:
10.1007/s12649-022-01688-y

6. A Metabolic Network Mediating the Cycling of Succinate, a Product of ROS Detoxification into α-Ketoglutarate, an Antioxidant

Author:
Félix Legendre; Alex MacLean; Sujeenthar Tharmalingam; Vasu D. Appanna
Source:
Antioxidants 2022 v.11 no.3 pp. -
ISSN:
2076-3921
Subject:
Pseudomonas; antioxidants; bacteria; biochemical pathways; byproducts; electrophoresis; glutamate decarboxylase; metabolites; oxidoreductases; quantitative polymerase chain reaction; soil microorganisms; succinic acid; sulfur
Abstract:
... Sulfur is an essential element for life. However, the soil microbe Pseudomonas (P.) fluorescens can survive in a low sulfur environment. When cultured in a sulfur-deficient medium, the bacterium reprograms its metabolic pathways to produce α-ketoglutarate (KG) and regenerate this keto-acid from succinate, a by-product of ROS detoxification. Succinate semialdehyde dehydrogenase (SSADH) and KG decar ...
DOI:
10.3390/antiox11030560

7. A Review on Synthetic and Pharmacological Potential of Compounds Isolated from Garcinia mangostana Linn

Author:
Swathy Unnikrishna Pillai Saraswathy; Lekshmi Chandran Pillai Lalitha; Sherifa Rahim; Chithra Gopinath; Simimole Haleema; Sumalekshmy SarojiniAmma; Hassan Y. Aboul-Enein
Source:
Phytomedicine plus 2022 v.2 no.2 pp. 100253
ISSN:
2667-0313
Subject:
Garcinia mangostana; antioxidants; apoptosis; cosmetics; databases; drugs; pericarp; pharmacokinetics; skeleton; xanthone
Abstract:
... : The extracts of Garcinia mangostana (L) pericarp contain high concentration of prenylated xanthones such as α-, β- and γ-mangostin and related molecules. These extracts possess wide range of biological properties including anticancer, anti-inflammatory, anti-proliferative, antioxidant and pro-apoptotic activities. Till date, α-, β- and γ-mangostin have been extensively studied due to its applica ...
DOI:
10.1016/j.phyplu.2022.100253

8. A bioinspired Janus polyurethane membrane for potential periodontal tissue regeneration

Author:
Yushui He; Xiao Wang; Yuanyuan He; Xin Zhao; Jingjing Lin; Yuan Feng; Jie Chen; Feng Luo; Zhen Li; Jiehua Li; Hong Tan
Source:
Journal of materials chemistry B 2022 v.10 no.14 pp. 2602-2616
ISSN:
2050-7518
Subject:
ammonium salts; antibacterial properties; antioxidants; biocompatibility; bones; cell adhesion; dopamine; epithelium; fibroblasts; mineralization; models; polyurethanes; quaternary ammonium compounds; rats; therapeutics; tissue repair; topology
Abstract:
... Guided tissue regeneration (GTR) is the main therapeutic method for periodontal tissue regeneration. The key to the GTR strategy is the membrane which can assist the reconstruction of bone tissue in the periodontal defect and prevent the migration of epithelium and fibroblasts to the defect. However, the existing periodontal membrane cannot effectively promote periodontal tissue regeneration due t ...
DOI:
10.1039/d1tb02068d

9. A comparative study on physicochemical properties and in vitro bioaccessibility of bioactive compounds in rosehip (Rosa canina L.) infusions treated by non‐thermal and thermal treatments

Author:
Gulay Ozkan; Anna‐Sophie Stübler; Kemal Aganovic; Gerald Draeger; Tuba Esatbeyoglu; Esra Capanoglu
Source:
Journal of food processing and preservation 2022 v.46 no.6 pp. e16096
ISSN:
0145-8892
Subject:
Rosa canina; antioxidant activity; antioxidants; bioactive compounds; bioavailability; comparative study; digestion; electric field; gallic acid; gastrointestinal system; heat treatment; nutritive value; pulsed electric fields; rose hips; rutin; specific energy
Abstract:
... The present study aimed to compare the effects of non‐thermal techniques with thermal treatment on physicochemical properties, bioaccessibility, and antioxidant capacity of bioactives in rosehip (Rosa canina) infusions. High pressure processing (HPP) at 200, 400, or 600 MPa for 5 and 15 min; pulsed electric field (PEF) with 5, 10, and 15 kJ/kg specific energy intakes at 1 and 3 kV/cm electric fiel ...
DOI:
10.1111/jfpp.16096

10. A comprehensive review on biocompatible film sensor containing natural extract: Active/intelligent food packaging

Author:
N.H. Azman; Wan M. Khairul; N.M. Sarbon
Source:
Food control 2022 v.141 pp. 109189
ISSN:
0956-7135
Subject:
antioxidants; biopolymers; cohesion; color; food safety; freshness; pH
Abstract:
... This review aims to provide a clear description of the compatibility between the main biopolymer matrix and the reinforcing components in manufacturing active and intelligent packaging film. The incorporation of natural extracts and/or nanomaterial improved the mechanical and barrier performance by increasing the cohesiveness of the biopolymer matrix. Meanwhile, the colour changes were due to the ...
DOI:
10.1016/j.foodcont.2022.109189

11. A detailed study on multifaceted bioactivities of the extracts and isolated compounds from truffle Reddellomyces parvulosporus

Author:
Fatih Çayan; Gülsen Tel‐Çayan; Ebru Deveci; Mehmet Emin Duru; Mustafa Türk
Source:
International journal of food science & technology 2022 v.57 no.3 pp. 1411-1419
ISSN:
0950-5423
Subject:
antioxidants; cytotoxicity; ergosterol; food additives; fumaric acid; mannitol; technology; thiourea; truffles
Abstract:
... Mushrooms and truffles are attracting attention as a new generation of biotherapeutics. In the current study, isolation, phenolic and organic acid composition, and antioxidant, cytotoxic, anticholinesterase activities of truffle Reddellomyces parvulosporus were examined. Four known compounds (brassicasterol (1), ergosterol peroxide (2), fumaric acid (3) and mannitol (4)) were isolated with the com ...
DOI:
10.1111/ijfs.15190

12. A dual-function chitosan packaging film for simultaneously monitoring and maintaining pork freshness

Author:
Wanmei Lin; Gengli Huang; Weixia Yang; Shuhao Zeng; Xueli Luo; Jihong Huang; Zhonghong Li
Source:
Food chemistry 2022 v.392 pp. 133242
ISSN:
0308-8146
Subject:
antioxidants; cell viability; chitosan; fluorescence; food chemistry; food safety; freshness; hemolysis; pH; plate count; pork; shelf life; total volatile basic nitrogen; weight loss
Abstract:
... Exploring food packaging films simultaneously possess freshness monitoring and maintaining can effectively tackle food safety issues. Here, we constructed a chitosan/N-doped carbon dots (CS/N-CDs) film which can monitor the freshness of pork based on pH-mediated fluorescent sensing and extend the shelf life based on the antioxidant, antibacterial and UV shielding properties. The fluorescent intens ...
DOI:
10.1016/j.foodchem.2022.133242

13. A hydrogel based on nanocellulose/polydopamine/gelatin used for the treatment of MRSA infected wounds with broad-spectrum antibacterial and antioxidant properties and tissue suitability

Author:
Lili Ren; Guoyi He; Yaxin Zhou; Jie Dai; Wenjun Miao; Chengcheng Ouyang; Jia Liu; Guoguang Chen
Source:
Biomaterials science 2022 v.10 no.12 pp. 3174-3187
ISSN:
2047-4849
Subject:
adhesion; antioxidants; bacterial infections; biocompatible materials; cell proliferation; cellulose; gelatin; hydrogels; inflammation; methicillin-resistant Staphylococcus aureus
Abstract:
... Most wound dressings encounter a series of problems when dealing with the bacterial infection of wounds, for example, the antibacterial and antioxidant capacities, comfort, and mechanical properties are not suitable to meet clinical requirements. Here, we synthesized ε-polylysine-grafted nanocellulose (NCF-EPL) and polydopamine (PDA) nanoparticles and embedded them in genipin-cross-linked gelatin ...
DOI:
10.1039/d2bm00157h

14. A hydrogen-bonded antibacterial curdlan-tannic acid hydrogel with an antioxidant and hemostatic function for wound healing

Author:
Zongbao Zhou; Jiangwei Xiao; Shuwen Guan; Zhijie Geng; Ruifang Zhao; Botao Gao
Source:
Carbohydrate polymers 2022 v.285 pp. 119235
ISSN:
0144-8617
Subject:
animal models; antioxidants; blood; carbohydrates; cytotoxicity; fibroblasts; hemolysis; hemostasis; hydrogels; hydrogen bonding; porosity; rheology; tannins
Abstract:
... Manufacturing facile and low-cost wound dressings that simultaneously meet the needs of the entire repair process remains the major challenge of effective wound healing. Herein, a series of curdlan-tannic acid hybrid hydrogels were successfully fabricated through the annealing technique. Notedly, when the mixing weigh ratio was 1:1, the hydrogel exhibited excellent physicochemical properties, incl ...
DOI:
10.1016/j.carbpol.2022.119235

15. A ketogenic diet attenuates acute and chronic ischemic kidney injury and reduces markers of oxidative stress and inflammation

Author:
Pedro Rojas-Morales; Juan Carlos León-Contreras; Mónica Sánchez-Tapia; Alejandro Silva-Palacios; Agustina Cano-Martínez; Susana González-Reyes; Angélica Saraí Jiménez-Osorio; Rogelio Hernández-Pando; Horacio Osorio-Alonso; Laura Gabriela Sánchez-Lozada; Armando R. Tovar; José Pedraza-Chaverri; Edilia Tapia
Source:
Life sciences 2022 v.289 pp. 120227
ISSN:
0024-3205
Subject:
Western blotting; acetylation; antioxidants; blood flow; fibrosis; high fat diet; histology; inflammation; interleukin-6; ischemia; ketogenic diet; ketone bodies; kidneys; liver; nephroprotective effect; oxidative stress; therapeutics
Abstract:
... Ischemic kidney injury is a common clinical condition resulting from transient interruption of the kidney's normal blood flow, leading to oxidative stress, inflammation, and kidney dysfunction. The ketogenic diet (KD), a low-carbohydrate, high-fat diet that stimulates endogenous ketone body production, has potent antioxidant and anti-inflammatory effects in distinct tissues and might thus protect ...
DOI:
10.1016/j.lfs.2021.120227

16. A low-swelling and toughened adhesive hydrogel with anti-microbial and hemostatic capacities for wound healing

Author:
Liwei Zhang; Yajie Zhang; Fanshu Ma; Xingzhu Liu; Yangzhong Liu; Yi Cao; Renjun Pei
Source:
Journal of materials chemistry B 2022 v.10 no.6 pp. 915-926
ISSN:
2050-7518
Subject:
adhesion; antioxidants; chitosan; fibroins; hydrogels; strength (mechanics); tannins; tissue repair
Abstract:
... Hydrogel-based wound dressings with tissue adhesion abilities are widely used for wound closure. However, currently developed hydrogel adhesives are still poor at continuing to seal wounds while bleeding is ongoing. Herein, we demonstrate an antibacterial and hemostatic hydrogel adhesive with low-swelling properties and toughness for wound healing. The hydrogel was composed of Pluronic F127 diacry ...
DOI:
10.1039/d1tb01871j

17. A new bioactive isocoumarin from the mangrove-derived fungus Penicillium sp. TGM112

Author:
Wei-Nv Zeng; Jin Cai; Bin Wang; Liang-Yu Chen; Chen-Xin Pan; Shi-Ji Chen; Guo-Lei Huang; Cai-Juan Zheng
Source:
Journal of Asian natural products research 2022 v.24 no.7 pp. 679-684
ISSN:
1477-2213
Subject:
Penicillium; antioxidant activity; antioxidants; circular dichroism spectroscopy; fungi; research; spectral analysis
Abstract:
... A new isocoumarin, penicimarin N (1), along with five known compounds (2-6), were isolated from the mangrove-derived fungus Penicillium sp. TGM112. The structure of 1 was elucidated on the basis of extensive spectroscopic data analysis, and the absolute configuration of 1 was determined by comparison of their circular dichroism (CD) spectra with the literature. The structures of known compounds we ...
DOI:
10.1080/10286020.2021.1952188

18. A non‐conventional approach for obtaining phenolic antioxidants from red guava (Psidium guajava L.) by‐products

Author:
Renan Danielski; Simone Mazzutti; Sandra Regina Salvador Ferreira; Luciano Vitali; Jane Mara Block
Source:
Journal of food processing and preservation 2022 v.46 no.6 pp. e16502
ISSN:
0145-8892
Subject:
Psidium guajava; antioxidant activity; antioxidants; dietary supplements; fruits; guavas; ingredients; liquids; naringin; pulp; resveratrol; scopoletin; solvents; toxicity; ultrasonics
Abstract:
... The recovery of phenolic antioxidants from agro‐industrial by‐products using non‐conventional techniques is a powerful tool to explore the bioactive potential of natural sources. Therefore, it is imperative to analyze the most suitable method to investigate a plant material’s phenolic composition. This study used ultra‐turrax (UTE), ultrasonic bath (BUAE), and pressurized liquid (PLE) for soluble ...
DOI:
10.1111/jfpp.16502

19. A novel reverse migration micellar electrokinetic chromatography method for in‐capillary screening and quantifying of antioxidant components in Sanyetangzhiqing using 2,2′‐Azinobis‐(3‐ethylbenzthiazoline‐6‐sulphonate) as oxidation‐free radical

Author:
Yaqi Yao; Shanshan Wang; Rui Zhou; Ye Shang; Kunze Du; Jun He; Jin Li; Lin Ma; Yanxu Chang
Source:
Electrophoresis 2022 v.43 no.11 pp. 1148-1160
ISSN:
0173-0835
Subject:
ammonium salts; antioxidant activity; antioxidants; diabetes; drugs; electrophoresis; micellar electrokinetic capillary chromatography; quality control; rosmarinic acid; salvianolic acid
Abstract:
... A novel method of reverse migration micellar electrokinetic chromatography (RM‐MEKC) using 2,2′‐azinobis‐(3‐ethylbenzthiazoline‐6‐sulphonate) as oxidation‐free radical was developed to screen the major antioxidants from Sanyetangzhiqing (SYTZQ), which is a new patent drug for diabetes. For simultaneous detection and separation of 2,2′‐bis (3‐ethylbenzothiazoline‐6‐sulfonic acid) ammonium salt (ABT ...
DOI:
10.1002/elps.202100330

20. A pH-intelligent response fish packaging film: Konjac glucomannan/carboxymethyl cellulose/blackcurrant anthocyanin antibacterial composite film

Author:
Peiqiong You; Lin Wang; Ning Zhou; Ying Yang; Jie Pang
Source:
International journal of biological macromolecules 2022 v.204 pp. 386-396
ISSN:
0141-8130
Subject:
anthocyanins; antioxidants; black currants; carboxymethylcellulose; composite films; fish; konjac mannan; meat products; microstructure; permeability; product quality; tensile strength; thermal stability; water vapor
Abstract:
... Blackcurrant anthocyanins (BCA) can be used to improve the structure and properties of konjac glucomannan (KGM)/carboxymethyl cellulose (CMC) composite film. In this study, the microstructure of the KGM/CMC/BCA composite film was evaluated. The results show that BCA is uniformly dispersed in the KC matrix, which changes the mechanical properties of the film (tensile strength (TS): 55.00 → 38.44 MP ...
DOI:
10.1016/j.ijbiomac.2022.02.027

21. A pharmaceutical formulation containing Cecropia pachystachya alleviates metabolic alterations in a hypercaloric diet obesity model in Swiss mice

Author:
Mara Lúcia de Campos; Maria Fernanda Fernandes; Marina B. de Castro; Artur D. Campos; Paula P. Pires; Rafaela de O. Andrade; Isadora M. de Oliveira; Aristóbolo M. da Silva; Céphora Maria Sabarense; Maria Christina M.N. Castañon; Ana Eliza Andreazzi; Elita Scio
Source:
Biocatalysis and agricultural biotechnology 2022 v.43 pp. 102376
ISSN:
1878-8181
Subject:
Cecropia; adipose tissue; adiposity; agricultural biotechnology; antioxidant activity; antioxidants; biocatalysis; blood glucose; diabetes; drug formulations; euthanasia; fatty liver; glucose; glucose tolerance; high energy diet; histopathology; liver; medicine; metformin; models; obesity
Abstract:
... Cecropia pachystachya is used in popular medicine in cases of diabetes and obesity. This study investigated the effects of a pharmaceutical formulation (ECP) containing C. pachystachya extract on some metabolic alterations caused by a hypercaloric diet in mice. After 12 weeks of being fed with a standard chow diet or hypercaloric diet, the mice were orally treated with ECP at 20, 40, and 80 mg/kg, ...
DOI:
10.1016/j.bcab.2022.102376

22. A polysaccharide from Lycium barbarum L.: Structure and protective effects against oxidative stress and high-glucose-induced apoptosis in ARPE-19 cells

Author:
Jianfei Liu; Yunchun Li; Qiaosheng Pu; Hongdeng Qiu; Duolong Di; Youlong Cao
Source:
International journal of biological macromolecules 2022 v.201 pp. 111-120
ISSN:
0141-8130
Subject:
Lycium barbarum; X-ray diffraction; anion exchange; antioxidants; apoptosis; arabinose; colorimetry; galactose; galacturonic acid; gel chromatography; glucose; glucuronic acid; hyperglycemia; oxidative stress; polysaccharides; rhamnose; thermal stability; thermogravimetry; vision
Abstract:
... Lycium barbarum polysaccharides (LBPs) are beneficial for vision; however, relevant research has mainly focused on entire crude polysaccharides, with the basis and exact structure of the polysaccharide rarely explored. In this study, LICP009-3F-2a, a novel polysaccharide from Lycium barbarum L., was separated and then purified using anion-exchange and size-exclusion chromatography. Structural char ...
DOI:
10.1016/j.ijbiomac.2021.12.139

23. A review of Sapodilla (Manilkara Zapota) in human nutrition, health, and industrial applications

Author:
Sneh Punia Bangar; Nitya Sharma; Harpreet Kaur; Maninder Kaur; Kawaljit Singh Sandhu; Sajid Maqsood; Fatih Ozogul
Source:
Trends in food science & technology 2022 pp. -
ISSN:
0924-2244
Subject:
Manilkara zapota; analgesics; anthocyanins; antioxidants; bark; calcium; chemical constituents of plants; dietary supplements; flavanols; food science; fruits; human nutrition; ingredients; iron; nutrient content; phenolic acids; potassium; sapodillas; technology
Abstract:
... Manilkara zapota, also known as Sapodilla, is the best-known and most widely cultivated fruit from Sapotaceae. Sapodilla is a rich source of nutrients (sugars, acids, protein, amino acids), minerals (potassium, calcium, and iron), and comprises of a myriad of bioactive compounds, which are chiefly composed of ellagitannins, gallotannins, phenolic acid, depsides, and flavonoids (anthocyanins and fl ...
DOI:
10.1016/j.tifs.2022.05.016

24. A review of the ethnomedicinal, pharmacology, cytotoxicity and phytochemistry of the genus Euphorbia in southern Africa

Author:
E.J. Mavundza; R. Street; H. Baijnath
Source:
South African journal of botany 2022 v.144 pp. 403-418
ISSN:
0254-6299
Subject:
Euphorbia; antimalarials; antioxidants; caffeic acid; catechin; cytotoxicity; intestines; larvicides; luteolin; migraine; quercetin; traditional medicine; Southern Africa
Abstract:
... Euphorbia L. is the largest genus in the plant family Euphorbiaceae with about 2000 species ranging from herbs to trees. Plants of this genus are used around the world to treat different kinds of ailments such as skin diseases, migraine, gonorrhoea and intestinal parasites. The present review aims to provide a comprehensive summary on the medicinal uses, pharmacology, cytotoxicity, and phytochemis ...
DOI:
10.1016/j.sajb.2021.08.029

25. A review on nanomaterials and nanohybrids based bio-nanocomposites for food packaging

Author:
Kalpani Y. Perera; Swarna Jaiswal; Amit K. Jaiswal
Source:
Food chemistry 2022 v.376 pp. 131912
ISSN:
0308-8146
Subject:
antioxidants; environmental impact; food chemistry; laws and regulations; nanocomposites; nanohybrids
Abstract:
... With an increasing demand for a novel, eco-friendly, high-performance packaging material “bio-nanocomposites” has attracted great attention in recent years. The review article aims at to evaluating recent innovation in bio-nanocomposites for food packaging applications. The current trends and research over the last three years of the various bio-nanocomposites including inorganic, organic nanomate ...
DOI:
10.1016/j.foodchem.2021.131912

26. A review on quality attributes and utilization of ghee residue, an under-utilized dairy by-product

Author:
Aakash Dadarao Wani; Writdhama Prasad; Kaushik Khamrui; Sristi Jamb
Source:
Future foods 2022 v.5 pp. 100131
ISSN:
2666-8335
Subject:
antioxidants; biodiesel; blood serum; buttermilk; byproducts; carboxylic ester hydrolases; color; flavor; ghee; milk; milk fat; sweets; whey
Abstract:
... Increasing global population has tremendously increased the pressure on existing food systems to feed the larger set of people. With limited food resources, contemporary food industries are focusing various approaches to increase their production capacity. Utilization of by-products for various food applications is one such approach. Although, by-products like whey and buttermilk have gained much ...
DOI:
10.1016/j.fufo.2022.100131

27. A state-of-art review on camel milk proteins as an emerging source of bioactive peptides with diverse nutraceutical properties

Author:
Ali Ali Redha; Hamidreza Valizadenia; Shahida Anusha Siddiqui; Sajid Maqsood
Source:
Food chemistry 2022 v.373 pp. 131444
ISSN:
0308-8146
Subject:
antioxidants; camel milk; dietary supplements; enzymatic hydrolysis; enzymes; fermentation; food chemistry; hydrolysis; molecular weight; peptides; systematic review; temperature
Abstract:
... The generation of camel milk derived bioactive peptides (CM-BAPs) have started to grab keen interest of many researchers during the past decade. CM-BAPs have shown more significant bioactive properties in comparison to camel milk intact proteins. CM-BAPs can be obtained using enzyme hydrolysis to form hydrolysates, or by the fermentation process. In this systematic review, 46 research articles exp ...
DOI:
10.1016/j.foodchem.2021.131444

28. Acclimatization of In Vitro Banana Seedlings Using Root-Applied Bio-Nanofertilizer of Copper and Selenium

Author:
Tarek A. Shalaby; Said M. El-Bialy; Mohammed E. El-Mahrouk; Alaa El-Dein Omara; Hossam S. El-Beltagi; Hassan El-Ramady
Source:
Agronomy 2022 v.12 no.2 pp. -
ISSN:
2073-4395
Subject:
acclimation; agronomy; antioxidants; bananas; bioavailability; fluorescence; greenhouses; pH; photosynthesis; selenium; survival rate
Abstract:
... The production of in vitro banana transplants has become an important practice in the global banana production. Proper and enough nutrients are needed for banana production particularly during the acclimatization period. To avoid the environmental problem resulting from the chemical fertilizers, nanofertilizers of Se and Cu were separately applied during the acclimatization of banana. The biologic ...
DOI:
10.3390/agronomy12020539

29. Aconitine induces autophagy via activating oxidative DNA damage-mediated AMPK/ULK1 signaling pathway in H9c2 cells

Author:
Wenlin Wang; Jialuo Jiang; Yan Huang; Fu Peng; Tingting Hu; Jiayang Wu; Xiaoqi Pan; Chaolong Rao
Source:
Journal of ethnopharmacology 2022 v.282 pp. 114631
ISSN:
0378-8741
Subject:
Aconitum; DNA; DNA damage; aconitine; antioxidants; arrhythmia; autophagosomes; autophagy; cardiomyocytes; cardiotoxicity; cell viability; confocal microscopy; death; enzyme-linked immunosorbent assay; fibrosis; flow cytometry; phosphorylation; protein synthesis; rheumatoid arthritis; toxicity; traditional medicine
Abstract:
... Aconitum species, with a medicinal history of 2000 years, was traditionally used in the treatment of rheumatism, arthritis, bruises, and pains. However, many studies have reported that Aconitum species can cause arrhythmia in experimental animals, resulting in myocardial fibrosis and cardiomyocyte damage. Cardiotoxicity is the main toxic effect of aconitine, but the detailed mechanism remains uncl ...
DOI:
10.1016/j.jep.2021.114631

30. Active Alyssum homolocarpum seed gum films containing microencapsulated Echinacea purpurea (L.) extract; study of physicochemical properties and its application in quail meat packaging

Author:
Bahareh Hajirostamloo; Mohammad Molaveisi
Source:
Journal of food measurement & characterization 2022 v.16 no.3 pp. 1997-2010
ISSN:
2193-4126
Subject:
Alyssum homalocarpum; Echinacea purpurea; antioxidants; edible films; gum arabic; measurement; meat; microencapsulation; models; permeability; porosity; quails; shelf life; spray drying; tensile strength; water vapor
Abstract:
... The present study was purposed to prepare an active film to increase the shelf life of quail meat. In this study, an edible film made of Alyssum homolocarpum seed gum (AHSG) was prepared. The AHSG film was enriched with different concentrations (0, 1, 5, 10, and 20% w/w based on AHSG) of microencapsulated Echinacea purpurea (L.) extract (MEE). Arabic gum was used as an encapsulating agent for the ...
DOI:
10.1007/s11694-022-01317-1

31. Acute Toxicity of the Tire Rubber-Derived Chemical 6PPD-quinone to Four Fishes of Commercial, Cultural, and Ecological Importance

Author:
Markus Brinkmann; David Montgomery; Summer Selinger; Justin G. P. Miller; Eric Stock; Alper James Alcaraz; Jonathan K. Challis; Lynn Weber; David Janz; Markus Hecker; Steve Wiseman
Source:
Environmental science & technology letters 2022 v.9 no.4 pp. 333-338
ISSN:
2328-8930
Subject:
Acipenser transmontanus; Oncorhynchus kisutch; Oncorhynchus mykiss; Salvelinus alpinus; Salvelinus fontinalis; acute toxicity; antioxidants; death; lethal concentration 50; mortality; risk; rubber; sturgeon; technology; urban runoff
Abstract:
... N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-quinone), a transformation product of the rubber tire antioxidant 6PPD, has recently been identified as the chemical responsible for urban runoff mortality syndrome in coho salmon, with a median lethal concentration (LC₅₀) of <0.1 μg/L. Subsequent studies have failed to confirm comparable sensitivity in other fish species. Here, we i ...
DOI:
10.1021/acs.estlett.2c00050

32. Acute and subchronic 90-days toxicity assessment of propyl-propane-thiosulfinate (PTS) in rats

Author:
Antonio Cascajosa-Lira; Silvia Pichardo; Alberto Baños; Enrique Guillamón; Verónica Molina-Hernández; Rosario Moyano; Ángeles Jos; Ana M Cameán
Source:
Food and chemical toxicology 2022 v.161 pp. 112827
ISSN:
0278-6915
Subject:
Allium; adverse effects; antioxidants; body weight; calcium; females; food consumption; food industry; gastrointestinal system; histopathology; musculoskeletal system; rats
Abstract:
... The organosulfur compounds (OSC) extracted from Allium spp. exhibit antibacterial, antifungal, and antioxidant properties. The agri-food industry is taking advantage of these properties by using them as natural feed and food additives. In the present work, an acute and a subchronic 90-days toxicity studies have been conducted for the first time to assess the safety of the OSC propyl-propane-thiosu ...
DOI:
10.1016/j.fct.2022.112827

33. Acute toxicity and sublethal effects of nitrite on oxidative stress in early juvenile Brazilian flounder, Paralichthys orbignyanus

Author:
Diego Henrique de Sousa Miranda; Lucas Campos Maltez; Marina Espírito Santo Campello; Joel Fitzgerald Linares Córdova; Ricardo Vieira Rodrigues; Luís André Sampaio; Marcelo Hideo Okamoto
Source:
Aquaculture research 2022 v.53 no.5 pp. 1939-1946
ISSN:
1355-557X
Subject:
Paralichthys orbignyanus; acute toxicity; antioxidant activity; antioxidants; aquaculture; flounder; glutathione transferase; juveniles; lipid peroxidation; mortality; nitrites; oxidative stress; research; thiols
Abstract:
... This study evaluated the acute toxicity and sublethal effects of nitrite on oxidative stress parameters in early juvenile Brazilian flounder, Paralichthys orbignyanus. Fish were exposed to six concentrations of nitrite: 20, 40, 80, 170, 330 and 550 mg NO₂⁻N‐L⁻¹, plus a control with no added nitrite, all in triplicate for 96 h. Every 24 h, the tanks were monitored to check possible mortality to est ...
DOI:
10.1111/are.15722

34. Agave tequilana Counteracts Chronic Hypertension and Associated Vascular Damage

Author:
Maribel Herrera-Ruiz; Zúlima Jannette Gutiérrez-Nava; Celeste Trejo-Moreno; Alejandro Zamilpa; Manasés González-Cortazar; Antonio Ruperto Jiménez-Aparicio; Enrique Jiménez-Ferrer
Source:
Journal of medicinal food 2022 v.25 no.4 pp. 443-455
ISSN:
1557-7600
Subject:
Agave tequilana; animal models; antioxidant activity; antioxidants; diastolic blood pressure; functional foods; gas chromatography-mass spectrometry; hypertension; immunomodulators; inflammation; interleukin-10; interleukin-6; intraperitoneal injection; lipid peroxidation; males; malondialdehyde; oxidative stress; tumor necrosis factor-alpha; vasoconstriction
Abstract:
... Systemic arterial hypertension (SAH) is a health problem of great importance worldwide, and endothelial dysfunction underlies SAH development. This condition's main characteristics include vasoconstriction, inflammation, oxidative stress, and procoagulant and proliferative states. This study's objective was to evaluate the antihypertensive, anti-inflammatory, and antioxidant effects of the whole e ...
DOI:
10.1089/jmf.2021.0044

35. Age-Associated Glia Remodeling and Mitochondrial Dysfunction in Neurodegeneration: Antioxidant Supplementation as a Possible Intervention

Author:
Anna Picca; Evelyn Ferri; Riccardo Calvani; Hélio J. Coelho-Júnior; Emanuele Marzetti; Beatrice Arosio
Source:
Nutrients 2022 v.14 no.12 pp. -
ISSN:
2072-6643
Subject:
antioxidants; astrocytes; brain; cytokines; endosomes; hypertrophy; lipids; lysosomes; metabolites; mitochondria; neurodegenerative diseases; neurotoxicity; oxidative stress; peroxisomes; secretion; transportation
Abstract:
... Aging induces substantial remodeling of glia, including density, morphology, cytokine expression, and phagocytic capacity. Alterations of glial cells, such as hypertrophy of lysosomes, endosomes and peroxisomes, and the progressive accumulation of lipofuscin, lipid droplets, and other debris have also been reported. These abnormalities have been associated with significant declines of microglial p ...
DOI:
10.3390/nu14122406

36. Agro-industrial by-products: Valuable sources of bioactive compounds

Author:
Lívia Mateus Reguengo; Mateus Kawata Salgaço; Katia Sivieri; Mário Roberto Maróstica Júnior
Source:
Food research international 2022 v.152 pp. 110871
ISSN:
0963-9969
Subject:
antioxidant activity; antioxidants; bioactive compounds; carotenoids; cost effectiveness; dietary supplements; flavonoids; food groups; food research; meat; mechanism of action; phytosterols; polyphenols
Abstract:
... In a world with eminent scarcity of natural resources and increasing incidence of chronic diseases related to unhealthy eating habits, the search for biologically active and environmentally friendly food products is raising among customers. Agro-industrial by-products have caught special attention from the scientific community for being an available, cost-effective and sustainable source of a wide ...
DOI:
10.1016/j.foodres.2021.110871

37. Albicanol inhibits the toxicity of profenofos to grass carp hepatocytes cells through the ROS/PTEN/PI3K/AKT axis

Author:
Xuan lihui; Guo Jinming; Guan Yalin; Wang Hemeng; Wu Hao; Chang Ying
Source:
Fish & shellfish immunology 2022 v.120 pp. 325-336
ISSN:
1050-4648
Subject:
Ctenopharyngodon idella; Dryopteris fragrans; antioxidants; apoptosis; caspase-3; caspase-8; caspase-9; fish; flow cytometry; food chain; gene expression; hepatocytes; humans; liver; mitochondria; models; oxidative stress; phosphorylation; pollutants; profenofos; sesquiterpenoids; shellfish; toxicity
Abstract:
... Profenofos (PFF) as an environmental pollutant seriously harms the health of aquatic animals, and even endangers human safety through the food chain. Albicanol, a sesquiterpenoid extraction from the Dryopteris fragrans, has previously been shown to effectively exhibit anti-aging, anti-oxidant, and antagonize the toxicity of heavy metals. However, the mechanism of hepatocyte toxicity caused by PFF ...
DOI:
10.1016/j.fsi.2021.11.014

38. Albicanol modulates oxidative stress and the p53 axis to suppress profenofos induced genotoxicity in grass carp hepatocytes

Author:
Xuan Lihui; Qiu Xiaojie; Yu Hao; Chu Jialiang; Guo Jinming; Chang Ying
Source:
Fish & shellfish immunology 2022 v.122 pp. 325-333
ISSN:
1050-4648
Subject:
Ctenopharyngodon idella; DNA; DNA damage; antioxidants; cell cycle; cyclin-dependent kinase; cyclins; fish; genotoxicity; heavy metals; hepatocytes; immunology; models; oxidative stress; profenofos; sesquiterpenoids; shellfish; tail
Abstract:
... The organophosphorus pesticide profenofos (PFF) is widely used as an environmental contaminant, and it can remain in water bodies causing serious harm to aquatic organisms. Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. However, the mechanism of PFF induced genotoxicity in fish hepatocytes and the role Albicanol can play in this pro ...
DOI:
10.1016/j.fsi.2022.02.002

39. Alginate based encapsulation of polyphenols of Piper betel leaves: Development, stability, bio-accessibility and biological activities

Author:
Ayesha Noor; Musa Al Murad; A. Jaya Chitra; Spoorthy N. Babu; S. Govindarajan
Source:
Food bioscience 2022 v.47 pp. 101715
ISSN:
2212-4292
Subject:
Piper betle; alginates; antioxidants; bioavailability; dietary supplements; digestion; encapsulation; extrusion; heat; microparticles; oxidation; pH; polyphenols; small intestine; taste; therapeutics
Abstract:
... Plant polyphenols have recently gained attention in nutraceutical and pharmaceutical industries due to their various therapeutic potentials. However, the polyphenols are prone to oxidation, unstable towards heat, light, pH and their unpleasant taste also limits their application. The usage of encapsulated polyphenols can alleviate these drawbacks and hence, efficient encapsulation methods have bee ...
DOI:
10.1016/j.fbio.2022.101715

40. Alginate-based multifunctional films incorporated with sulfur quantum dots for active packaging applications

Author:
Zohreh Riahi; Ruchir Priyadarshi; Jong-Whan Rhim; Ensieh Lotfali; Reza Bagheri; Gholamreza Pircheraghi
Source:
Colloids and surfaces 2022 v.215 pp. 112519
ISSN:
0927-7765
Subject:
Escherichia coli; alginates; antibacterial properties; antifungal properties; antioxidants; breads; chronic exposure; cytotoxicity; fibroblasts; functional foods; fungi; hot water treatment; mice; modulus of elasticity; permeability; polymers; sulfur; tensile strength; water vapor
Abstract:
... Sulfur quantum dots (SQDs) were fabricated using a facile hydrothermal method and used for the preparation of functional food packaging film and compared the properties with other sulfur-based fillers like elemental sulfur (ES) and sulfur nanoparticles (SNP). The SQDs have an average size of 5.3 nm and were very stable in aqueous suspension. Unlike other sulfur-based fillers, the SQD showed high a ...
DOI:
10.1016/j.colsurfb.2022.112519

41. Alkyl chain length modulates antioxidant activity of gallic acid esters in spray-dried emulsions

Author:
Sten ten Klooster; Pierre Villeneuve; Claire Bourlieu-Lacanal; Erwann Durand; Karin Schroën; Claire Berton-Carabin
Source:
Food chemistry 2022 v.387 pp. 132880
ISSN:
0308-8146
Subject:
antioxidant activity; antioxidants; carbon; encapsulation; food chemistry; gallic acid; lipid peroxidation; low moisture foods; milk; spray drying
Abstract:
... Lipid oxidation is a well-recognized issue in dried food emulsions, such as infant milk formula. Antioxidants can be used to mitigate this issue; however, their efficiency in such complex systems is far from understood. In this study, antioxidant polarity is varied through the alkyl chain length of gallic acid esters (0–16 carbon atoms) incorporated to O/W emulsions that are subsequently spray-dri ...
DOI:
10.1016/j.foodchem.2022.132880

42. All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Apoptosis in IPEC-J2 Cells via Inhibiting ROS-Mediated P38MAPK Signaling Pathway

Author:
Junning Pu; Daiwen Chen; Gang Tian; Jun He; Zhiqing Huang; Ping Zheng; Xiangbing Mao; Jie Yu; Junqiu Luo; Yuheng Luo; Hui Yan; Bing Yu
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
Transmissible gastroenteritis virus; antioxidant activity; antioxidants; apoptosis; caspase-3; caspase-8; caspase-9; death domain receptors; diarrhea; epithelial cells; metabolites; mitochondria; mortality; occludins; phosphorylation; retinoic acid; transmissible gastroenteritis; vitamin A
Abstract:
... Transmissible gastroenteritis virus (TGEV) can cause diarrhea, dehydration, and high mortality in piglets, which is closely related to intestinal epithelial cell apoptosis caused by TGEV infection. All-trans retinoic acid (ATRA) is the active metabolite of vitamin A, which has antioxidant and anti-apoptotic properties. However, it is unknown whether ATRA can attenuate TGEV-induced IPEC-J2 cells ap ...
DOI:
10.3390/antiox11020345

43. Alleviation of Dyslipidemia via a Traditional Balanced Korean Diet Represented by a Low Glycemic and Low Cholesterol Diet in Obese Women in a Randomized Controlled Trial

Author:
Min Jung Kim; Sunmin Park; Hye Jeong Yang; Phil-Kyung Shin; Haeng Jeon Hur; Seon-Joo Park; Kyun-Hee Lee; Moonju Hong; Jin Hee Kim; Sang-Woon Choi; Hae-Jeung Lee; Myung-Sunny Kim
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
3-hydroxybutyric acid; antioxidants; blood serum; cholesterol; energy intake; glucose; glutamic acid; glutathione; glycemic index; hyperlipidemia; insulin; insulin resistance; lipid metabolism; lipoproteins; low cholesterol diet; metabolites; randomized clinical trials; triacylglycerols; tryptophan; tyrosine; waist circumference
Abstract:
... A traditional balanced Korean diet (K-diet) may improve energy, glucose, and lipid metabolism. To evaluate this, we conducted a randomized crossover clinical trial, involving participants aged 30–40 years, who were randomly assigned to two groups—a K-diet or westernized Korean control diet daily, with an estimated energy requirement (EER) of 1900 kcal. After a 4-week washout period, they switched ...
DOI:
10.3390/nu14020235

44. Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities, Molecular Docking, and Antioxidant Capacities of Plectranthus ecklonii Constituents

Author:
Ninon G. E. R. Etsassala; Jelili A. Badmus; Jeanine L. Marnewick; Samuel Egieyeh; Emmanuel. I. Iwuoha; Felix Nchu; Ahmed A. Hussein
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
Plectranthus; absorption; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; blood glucose; digestion; diterpenoids; epigallocatechin gallate; glucose; insulin; insulin secretion; risk
Abstract:
... Shortage in insulin secretion or degradation of produced insulin is the principal characteristic of the metabolic disorder of diabetes mellitus (DM). However, because the current medications for the treatment of DM have many detrimental side effects, it is necessary to develop more effective antidiabetic drugs with minimal side effects. Alpha-glucosidase and alpha-amylase inhibitors are directly i ...
DOI:
10.3390/antiox11020378

45. Alternative Perspective on Rapid Wine Oxidation through Changes in Gas-Phase Volatile Concentrations, Highlighted by Matrix Component Effects

Author:
Wenyao Zhu; Frank Benkwitz; Paul A. Kilmartin
Source:
Journal of agricultural and food chemistry 2022 v.70 no.20 pp. 6177-6190
ISSN:
1520-5118
Subject:
antioxidants; ascorbic acid; copper; food chemistry; hydrophobicity; odors; oxidation; oxygen; partial pressure; polyphenols; spectroscopy; temperature; time series analysis; winemaking; wines
Abstract:
... A new perspective is presented to investigate the sensorially relevant gas-phase concentrations of volatile compounds in wine. This is achieved by measuring the partition coefficients and matrix-phase concentrations of volatiles using static headspace-gas chromatography-ion mobility spectrometry. Physicochemical properties that can contribute to the partition behaviors of 10 volatile esters, such ...
DOI:
10.1021/acs.jafc.2c00437

46. Alternative medicine: therapeutic effects on gastric original signet ring carcinoma via ascorbate and combination with sodium alpha lipoate

Author:
Weiyu Chen; Lingyun Xu; Edwin Chang; Gayatri Gowrishankar; Katherine W. Ferrara; Sanjiv Sam Gambhir
Source:
BMC complementary medicine and therapies 2022 v.22 no.1 pp. 58
ISSN:
2662-7671
Subject:
adenocarcinoma; alternative medicine; antioxidants; cell proliferation; dose response; growth retardation; humans; organoids; prognosis; sodium
Abstract:
... BACKGROUND: Gastric signet ring cell carcinoma (SRCC) is an aggressive gastric adenocarcinoma with a poor prognosis when diagnosed at an advanced stage. As alternative medicine, two natural supplements (ascorbate (AA) and sodium alpha lipoate (LA)) have been shown to inhibit various cancers with mild side effects. METHODS: These two natural supplements and a series of combinations (AA&LA, AA+LA an ...
DOI:
10.1186/s12906-022-03541-0

47. Amaranthus hybridus Linn. leaf extract ameliorates oxidative stress and hepatic damage abnormalities induced by thioacetamide in rats

Author:
Emmanuel U. Ejiofor; Sunday O. Oyedemi; Samuel O. Onoja; Ndukaku Y. Omeh
Source:
South African journal of botany 2022 v.146 pp. 213-221
ISSN:
0254-6299
Subject:
Amaranthus hybridus; antioxidant activity; antioxidants; ascorbic acid; benzene; biomarkers; catalase; disease control; dose response; fibrosis; gallic acid; histopathology; leaf extracts; liver; liver diseases; oxidative stress; protein content; quercetin; rats; superoxide dismutase
Abstract:
... A hydroalcoholic leaf extract of Amaranthus hybridus (HLEAH) at doses of 100, 200, and 400 mg/kg was investigated for its antioxidant and hepatoprotective effects on thioacetamide (TAA)- induced hepatic damage in rats. Liver damage was induced by administering TAA (300 mg/L) in drinking water for 10 weeks. The total phenolic, flavonoid, and ascorbic acid contents were 14.12±0.01 mg gallic acid equ ...
DOI:
10.1016/j.sajb.2021.10.029

48. Amelioration of cadmium toxicity by enhancing nitrogen assimilation and photosynthetic activity by two different nitrogen supplements in rice (Oryza sativa L.) cv. Lalat

Author:
Surupa Paul; Titir Guha; Swarnali Dey; Subhabrata Paul; Rita Kundu
Source:
Plant Stress 2022 v.4 pp. 100082
ISSN:
2667-064X
Subject:
Oryza sativa; agricultural soils; agrochemicals; ammonium acetate; antioxidant activity; antioxidants; bioavailability; biomass; cadmium; calcium nitrate; cultivars; grain quality; human health; industrialization; lipid peroxidation; nitrogen; photosynthesis; plant growth; plant stress; proline; protein content; rice; risk; salicylic acid; silicon; thiols; toxicity; vigor
Abstract:
... Rapid industrialization and over-use of agrochemicals may lead to cadmium (Cd) contamination in agricultural soil, posing serious threat to human health. In recent times, application of plant nutrients and other growth promoting substances, like, nanoparticles (nZVI), silicon, salicylic acid were reported to have ameliorated Cd toxicity, in this regard, nitrogen (N) amendment can be a promising te ...
DOI:
10.1016/j.stress.2022.100082

49. Ameliorative effect of enhanced Fischer ratio flaxseed protein hydrolysate in combination with antioxidant micronutrients on ethanol-induced hepatic damage in a rat model

Author:
Nida Ume Salma; K. Govindaraju; Belur Shivappa Gnanesh Kumar; S.P. Muthukumar; A. Jyothi Lakshmi
Source:
British journal of nutrition 2022 v.127 no.5 pp. 696-710
ISSN:
1475-2662
Subject:
alanine transaminase; alcohol abuse; alkaline phosphatase; animal models; antioxidant activity; antioxidants; aspartate transaminase; bilirubin; charcoal; dietary supplements; enzymatic hydrolysis; ethanol; hepatoprotective effect; hepatotoxicity; isoleucine; leucine; linseed; liver; liver function; malnutrition; nutritional status; peptides; phenylalanine; protein hydrolysates; selenium; therapeutics; tyrosine; vitamin E
Abstract:
... Alcohol abuse causes severe metabolic abnormalities inducing hepatic damage and malnutrition. Since higher Fischer ratio proteins have therapeutic value in liver diseases, an investigation was undertaken to study the ameliorative effect of the enhanced Fischer ratio flaxseed protein hydrolysate (EFR-FPH) alone and in combination with antioxidant micronutrients on ethanol-induced hepatotoxicity in ...
DOI:
10.1017/S000711452100115X

50. Aminomethylphosphonic acid (AMPA) alters oxidative status during embryonic development in an amphibian species

Author:
Marion Cheron; David Costantini; Frédéric Angelier; Cécile Ribout; François Brischoux
Source:
Chemosphere 2022 v.287 pp. 131882
ISSN:
0045-6535
Subject:
amphibians; antioxidants; catalase; embryogenesis; embryonic mortality; glutathione peroxidase; glyphosate; homeostasis; metabolites; mortality; oxidative stress; physiological state; superoxide dismutase; telomeres; thiols; wildlife
Abstract:
... Glyphosate's primary metabolite (aminomethylphosphonic acid, AMPA) is known to alter embryonic development at environmentally relevant concentrations in amphibians. However, we have limited understanding of the physiological mechanisms through which AMPA affects organisms. In this study, we tested whether alteration of the oxidative status is one mechanism through which AMPA affects organism perfo ...
DOI:
10.1016/j.chemosphere.2021.131882