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antioxidants; black beans; butanol; countercurrent chromatography; daidzein; daidzin; dietary supplements; enzyme inhibition; genistein; genistin; mass spectrometry; monoterpenoids; nuclear magnetic resonance spectroscopy; saponins; secondary metabolites; separation; soybeans; xanthine oxidase
Abstract:
... Black bean, in which isoflavones are the main active constituent, also contains saponins and monoterpenes. Soybean isoflavone is a secondary metabolite that is formed during the growth of soybean; it exhibits antioxidant and cardiovascular activities and traces estrogen‐like effects. In this study, black bean isoflavones were extracted with n‐butanol, and ultrafiltration–liquid chromatography–mass ...
antioxidants; aquaporins; cultivars; gene expression; heat; photosynthesis; rice; salinity; salt stress; seedlings; transcription (genetics); water content
Abstract:
... Here, for the first time, we aimed to identify in rice the key mechanisms and processes underlying tolerance to high-temperature (HT) or salt stress (SS) alone, the co-occurrence of both stresses, and recovery using physiological and biochemical measurements and gene expression analysis. We also investigated whether recovery from the two stressors depended on the relative intensities/relief of eac ...
... Microplastics can accumulate residual drugs and heavy metals in the environment and accumulate through the layers of the food chain, ultimately causing harm to human health. The pollution of microplastics in the freshwater environment is becoming more and more serious, which directly affects the safety of aquatic organisms. This experiment studied the effects of single and composite microplastics ...
... Ammonia and nitrite are two of the most toxic substances for ecosystems and aquatic organisms. The present study aimed to investigate the single and combined effects of ammonia and nitrite on hematological parameters, antioxidant defenses, acetylcholinesterase, and acid phosphatase activities in common carp. First, LC₅₀–96 h of ammonia and nitrite in common carp were determined. Second, fish were ...
... Nano- and microplastics pose severe risks to the ecological environment. Nanoplastics (NPs) not only directly affect aquatic organisms, but also adsorb to other pollutants, resulting in compound pollution. Bisphenol F (BPF), an endocrine-disrupting chemical, is increasingly replacing bisphenol A (BPA) and is therefore widely distributed in the environment. In this study, the toxic effects of polys ...
... Rubraxanthone is a main active constituent of kandis (Garcinia cowa Roxb), has showed many biological activity including antimicrobial, anti hypercholesterolemic, antiplatelet, antioxidant, cytotoxic, and anti-inflammatory properties. To the best of our knowledge, no reports on the pharmacokinetics (PK) of this rubraxanthone have been published. The PK of rubraxanthone in mice was examined after a ...
... The aim of this work is to comprehend the biphasic reaction systems through another perspective; the simultaneous purification and production of carbohydrates during the pretreatment of biomass. A dilute acid hydrolysis of almond shells in a 2-Methyltetrahydrofuran/H₂O system was optimised to maximise the obtaining of hemicellulose-derived monosaccharides with the minimum formation of degradation ...
... In this study, alterations in behavior, oxidative stress, and related gene expressions, as well as histopathological changes in the brain, of zebrafish were evaluated following exposure to cadmium chloride and mercury chloride alone and in combination for 21 days. In the light–dark preference test, the time spent in the dark side and numbers of entries in the light side by zebrafish of all toxicit ...
Lens culinaris; amino acid composition; amino acids; antioxidant activity; antioxidants; atomic force microscopy; bitterness; butylated hydroxytoluene; denaturation; enzymatic hydrolysis; gel chromatography; hydrolysis; lentils; molecular weight; peptides; peptidyl-dipeptidase A; phenols; polyacrylamide gel electrophoresis; protein concentrates; subtilisin; taste; thermal stability; umami
Abstract:
... This study aimed to produce bioactive peptides with increased angiotensin‐converting enzyme (ACE)‐inhibitory and antioxidant activities from single and sequential hydrolysis, using Alcalase and Flavourzyme at the enzyme to substrate ratio of 2% and hydrolysis time of 180 min. Results indicated that sequential hydrolysis led to a higher degree of hydrolysis (DH) value (47.05%) compared with single ...
... The aim of the present study was to investigate the toxicity effects of cadmium–nickel (Cd–Ni) after single and mixtures exposures over the macrophyte Lemna gibba. Effects were assessed on growth, as frond number and fresh weight and biochemical parameters, such as total protein content and activity of antioxidant enzymes. Plants were exposed to single Cd and Ni in concentrations that ranged betwe ...
... Poultry production faces several threats and challenges, one of the most important of which is avian coccidiosis which causes annual losses exceeding US$ 3 billion. Discovering new drugs or combinations of existing anticoccidials has become inevitable to overcome the emergence of coccidiosis resistance. This study evaluated a new combination of maduramicin and diclazuril in comparison to the well- ...
... Pregnancy in sheep is a physiological condition characterized by a significant increase in energy demand to ensure adequate foetal growth and development, making them susceptible to oxidative stress. The aim of this study was to analyse the markers of oxidative stress in sheep during pregnancy, parturition and close to peripartum (up to 48 h postpartum), comparing single with twin gestation. Sixty ...
... The aim of the present study was to investigate the potential effects of dietary synbiotic (SYN) (Pediococcus acidilactici + Galactooligosaccharides; 10 g kg⁻¹), sodium propionate (SP; 5, 10 and 20 g kg⁻¹) and a combination of SYN + SP on the growth performance, humoral immunity, antioxidant responses and disease resistance against Aeromonas hydrophila of African cichlid (Labidochromis lividus) fi ...
air; antioxidants; density functional theory; electronics; graphene; oxidation; vapors
Abstract:
... Wafer-scale single-crystal graphene with strong antioxidation is fundamentally important for their applications in electronics and optoelectronics. Although significant progress has been achieved in the chemical vapor deposition (CVD) growth of graphene, the production of wafer-scale graphene with high crystalline and excellent oxidation resistance still remains a challenge. Here, we report the ep ...
... Valorization of wastes has become an unavoidable goal in the olive oil industry. A possible approach is the recovery of leaf phenolic compounds, which have a great interest for food industries, due to their antioxidant and antimicrobial activities. Thus, this study aims at comparing the effects of encapsulated (e-OLE) and free olive leaf extract (f-OLE) on storage stability of salad dressings prep ...
Ronit Shiri-Sverdlov; Inês Magro dos Reis; Yvonne Oligschlaeger; Tim Hendrikx; Dennis M. Meesters; Annick Vanclooster; Nele Vanhoutvin; Ger H. Koek; Marit Westerterp; Christoph J. Binder; David Cassiman; Tom Houben
... As a mediator between lipid metabolism dysfunction, oxidative stress and inflammation, oxidized low-density lipoprotein (oxLDL) is a promising therapeutical target in a wide range of metabolic diseases. In mice, pneumococcal immunization increases anti-phosphorylcholine and oxLDL antibody levels, and reduces atherosclerosis, non-alcoholic steatohepatitis and Niemann–Pick disease burden. These find ...
... Gestational exposure to environmental pollutants can induce oxidative injury and apoptosis since the fetal organs are sensitively vulnerable to these chemicals. In this work, we have investigated the renal anti‐apoptotic efficiency of linseed (LS) against the oxidative stress‐mediated upregulation of the fetal apoptosis‐related genes following the prenatal intoxication with diesel nanoparticles (D ...
Andreii S. Kritchenkov; Anton R. Egorov; Olga V. Volkova; Alexey A. Artemjev; Aleh V. Kurliuk; Tuan Anh Le; Hong Hieu Truong; Giang Le-Nhat-Thuy; Thanh Van Tran Thi; Nguyen Van Tuyen; Victor N. Khrustalev
... We used nanoparticles which possess simultaneously active (antimicrobial, UV-protective and antioxidant) and smart (temperature sensing) properties. The nanoparticles (2Rh = 450 nm, PDI = 0.118 ± 0.014, ζ-potential = 21 mV and Tg = 8 ± 1 °C) are based on polyethylene glycol (PEG)/methyl cellulose (MC) core with anthocyanidin and sodium acetate, and chitosan/gallotannin-based shell. The core of nan ...
... Algae are natural products with great potential as aquafeed ingredients, being rich in nutrients and bioactive compounds. They can improve fish health while being sustainable at social, economic, and environmental levels, contributing to the one health concept. In this study, two micro- (Nannochloropsis oceanica and Chlorella vulgaris) and two macroalgae (Gracilaria gracilis and Ulva rigida), prod ...
... A single factor experiment design was employed to optimize ultrasonic assisted extraction of Hibiscus cannabinus L. (kenaf) leaves. Ethanol concentration and extraction times (min) were optimized in the study as this extraction parameters were believed to have effect on the recovery of bioactive compounds derived from kenaf leaves extract (KLE). Considering all the results obtained from the experi ...
adults; antioxidants; cross-over studies; half life; high performance liquid chromatography; inflammation; intravenous injection; mass spectrometry; pharmacokinetics; thiamin
Abstract:
... Thiamine is a vital co‐factor for several anti‐inflammatory and antioxidant processes that are critical for mitigation of sepsis‐associated inflammation, but pharmacokinetic (PK) analysis has not been reported in horses. We hypothesized that IV thiamine hydrochloride (TH) at increasing dosages would result in corresponding increases in plasma thiamine concentrations without causing adverse effects ...
... While heavy metals (HMs) naturally occur in soil, anthropogenic activities can increase the level of these toxic elements. Conocarpus lancifolius Engl. (Combretaceae) was investigated as a potential phytoremediator of soils contaminated with HM containing crude oil. This study assessed the potential of C. lancifolius (CL), a locally available plant species in Kuwait, for resolving local issues of ...
Alberto J. Huertas-Alonso; Mohsen Gavahian; Diego J. González-Serrano; Milad Hadidi; Manuel Salgado-Ramos; M. Prado Sánchez-Verdú; Mario J. Simirgiotis; Francisco J. Barba; Daniel Franco; José M. Lorenzo; Andrés Moreno
... The table olive industry is producing a huge amount of wastewater, which is a post-processing cost and an environmental concern. The present study aims to valorize this processing by-product to obtain a value-added product, thereby enhancing resource efficiency and contributing to achieving sustainable development goals (SDGs). In this sense, a chemical reaction-based platform was developed to obt ...
... In the present study, we aimed to evaluate the single or conjoint effects of Lactococcus lactis (L. lactis) L19 and Enterococcus faecalis (E. faecalis) W24 isolated from the intestine of Channa argus (C. argus) on digestive enzyme activity, antioxidant capacity, intestinal microbiota and morphology of C. argus (initial weight, 9.50 ± 0.03 g). The fish were fed for 56 days with a basal diet (CK) or ...
... Contaminated poultry meat is a major source of human foodborne illnesses. Many interventions have been developed to reduce and/or eliminate human foodborne pathogens in poultry products; however, treatments with cold plasma or carnosine or their combination have not been extensively investigated. In this study, the bacterial microflora of poultry meat samples after treatments with cold plasma and ...
... Malnutrition is a serious issue in the developing countries especially in Pakistan. It may be due to ever growing population, urbanization and industrialization along with decrease in agricultural lands. It ultimately is an alarming situation for food security, thus, there is a need to look for alternate sources for food and nutrition security. Therefore, the objective of this project was to produ ...
Adrian S. Siregar; Marie Merci Nyiramana; Eun-Jin Kim; Eui-Jung Shin; Min Seok Woo; Jin-Mok Kim; Jung Hwan Kim; Dong Kun Lee; Jong Ryeal Hahm; Hyun Joon Kim; Chang-Woon Kim; Nam-Gil Kim; Si-Hyang Park; Yeung Joon Choi; Sang Soo Kang; Seong-Geun Hong; Jaehee Han; Dawon Kang
... Accumulative alcohol hangovers cause liver damage through oxidative and inflammatory stress. Numerous antioxidant and anti-inflammatory reagents have been developed to reduce alcohol hangovers, but these reagents are still insignificant and have limitations in that they can cause liver toxicity. Oyster hydrolysate (OH), another reagent that has antioxidant and anti-inflammatory activity, is a prod ...
A. Barreto; A. Carvalho; D. Silva; E. Pinto; A. Almeida; P. Paíga; L. Correira-Sá; C. Delerue-Matos; T. Trindade; A.M.V.M. Soares; K. Hylland; S. Loureiro; M. Oliveira
... In vitro methods have gained rising importance in ecotoxicology due to ethical concerns. The aim of this study was to assess the single and combined in vitro effects of gold, as nanoparticle (AuNPs) and ionic (Au⁺) form, and the pharmaceutical gemfibrozil (GEM). Sparus aurata liver organ culture was exposed to gold (4 to 7200 μg·L⁻¹), GEM (1.5 to 15,000 μg·L⁻¹) and combination 80 μg·L⁻¹ gold +150 ...
... Ultrasonication is an emerging nonthermal process to extract pectins and pectic-polysaccharides from natural sources. This review aimed to highlight recent results of techno-functional (e.g., water and oil holding capacities, foaming capacity and stability, emulsifying activity, emulsion stability, rheological and pasting properties, and tin corrosion inhibitory activity) and biofunctional (e.g., ...
... In the current post-antibiotic era, botanicals represent one of the most employed nutritional strategies to sustain antibiotic-free and no-antibiotic-ever production. Botanicals can be classified either as plant extracts, meaning the direct products derived by extraction from the raw plant materials (essential oils (EO) and oleoresins (OR)), or as nature-identical compounds (NIC), such as the chem ...
antioxidant activity; antioxidants; chemical composition; coffee (beverage); coffee beans; color; covariance; flavor; gallic acid; gases; human health; mass spectrometry; monitoring; prediction; process control; regression analysis; roasting
Abstract:
... Precise controlling and monitoring the status of the coffee roasting process is essential for consistent product quality and optimization toward targeted coffee properties. In small-scale roasting experiments, the chemical composition of the roasting off-gas was analyzed by online single-photon ionization time-of-flight mass spectrometry (SPI–TOFMS) at 118 nm with 5 s time resolution. Subsequently ...
... This study evaluates the effect of dietary supplementation of immunostimulants on the Chinese mitten crab (Eriocheir sinensis) with a single administration of mannan oligosaccharide (MOS), or its combination with either β-glucan or with inulin for 8 weeks. Four diets included an untreated control diet (C), MOS alone (3 g kg−1, M), MOS with β-glucan (3 g kg −1 MOS + 1.5 g kg −1 β-glucan, MB), and M ...
... This study evaluated the effect of addition of kaempferol alone or combined with other antioxidants (transferrin, selenium and ascorbic acid) on in vitro culture of sheep isolated secondary follicles and if PI3K pathway is involved in kaempferol action. Secondary follicles were isolated and cultured for 12 days in α-Minimal Essential Medium (α-MEM) supplemented with BSA, insulin, glutamine and hyp ...
... One of the main challenges in the food industry is to design strategies for the successful incorporation of natural sources of bioactive compounds. Recently, yogurts and other fermented dairy beverages have been proposed as ideal carriers of such bioactive compounds such as fatty acids and antioxidants that could improve consumers' health. However, the incorporation of new ingredients causes funct ...
DNA; DNA damage; antioxidants; biotechnology; chronic exposure; comet assay; males; malondialdehyde; oxidants; oxidative stress; pollution; radio waves; rats; tail; testes
Abstract:
... The testes are a sensitive organ to electromagnetic pollution and people are concerned about the harmful effects of the radiofrequency radiation (RFR) emitted from cellular phones. Therefore, the purpose of this study was to investigate the effects of long-term exposure to different RFR frequencies on single-strand DNA breaks and oxidative changes in rat testicular tissue. Twenty-eight male Spragu ...
... Copper is essential for plant growth, but in excess may cause adverse effects on plant physiology. Harmful effects are also caused by plant exposure to salinity (NaCl) due to the excessive use of fertilizers, soil degradation and/or the quality of the water used for irrigation. The impact of single and combined salinity (Sal) and copper (Cu) stress on spearmint metabolism were studied in hydroponi ...
antioxidants; biomedical research; chemiluminescence; detection limit; early diagnosis; electric field; electrophoresis; free radicals; glutathione; liver; rats; toxins
Abstract:
... Glutathione (GSH) is a major endogenous antioxidant that has a central role in cellular defense against toxins and free radicals. Rapid and accurate detection of GSH content in single cells is important to the early diagnosis of disease and biomedical research. In this work, a novel method based on microchip electrophoresis chemiluminescence (MCE-CL) detection was developed for the quantification ...
Allium cepa; Bayesian theory; DNA; DNA fingerprinting; antioxidants; cultivars; databases; farmers; genetic distance; genotyping; green onions; heterozygosity; open pollination; phylogeny; plant breeding; polyphenols; quality control; sequence analysis; single nucleotide polymorphism; spring; sulfur; Japan; Korean Peninsula
Abstract:
... Onions (Allium cepa L.) are a medicinally and economically important vegetable species rich in sulphur compounds, polyphenols, and antioxidants. In Korea, most of the onion cultivars are of the open-pollinated, heterozygous, short duration, and early spring type, which are generally harvested in April. Precise varietal identification is crucially important to warrant the authenticity of supreme on ...
... Traditionally, Zizyphus jujuba is used for anticonvulsant, hypnotic-sedative, anxiolytic, tranquilizer, antioxidant and anti-inflammatory properties. Likewise silymarin is popularly used for its potent antioxidant and hepatoprotective effects. Stroke being a multifactorial disease with unsatisfactory treatment outcomes, necessitates development of multimodal therapeutic interventions. Thus, we eva ...
... Despite their advantages, there is concern that single-use systems used in biopharmaceutical manufacture might release potentially toxic substances during standard unit operations that negatively impacting cell growth. Characterization of the extractables profile for single-use systems is necessary to know which compounds potentially become leachables under operational cell culture conditions. A k ...
... The minimal genome of the mollicute Mycoplasma hyopneumoniae, the etiological agent of porcine enzootic pneumonia, encodes a limited repertoire of antioxidant enzymes that include a single and atypical peroxiredoxin (MhPrx), whose evolution and function were studied here. MhPrx has only one catalytic cysteine, in contrast with some of its possible ancestors (2-Cys peroxiredoxins), which have two. ...
antioxidants; biofortification; chromosome mapping; corn; human health; inbred lines; microsatellite repeats; phenotypic variation; quantitative trait loci; seeds; single nucleotide polymorphism; vitamin A
Abstract:
... Carotenoids are antioxidants and vitamin A precursors that have important roles in human health. Hence, improving the carotenoid contents in maize kernels is a priority objective for breeders in order to obtain nutritional biofortification outcomes. In the current study, the genetic architecture of carotenoids in maize kernels was explored using a recombinant inbred line (RIL) population derived f ...
... A glassy carbon electrode surface was modified with a new combination of chitosan, single walled carbon nanotubes (SWCNT) and neodymium(iii) oxide (NdOX) and was found to be effective in the detection of rutin (RU), a natural antioxidant. The modified electrode displayed high activity toward the oxidation of RU compared to other flavonoids, such as quercetin (Q) and morin (MO). The oxidation peaks ...
... The development of a method for darkening black ripe olives during the washing step with a single NaOH treatment and preservation liquid was studied. Olives of the Hojiblanca cultivar were darkened at pilot plant scale, packed, sterilized, and analyzed after 2 mo of storage at ambient temperature. It was found that the use of a mixture of preservation liquid:water at a ratio of 1:1 during the firs ...
antioxidants; butylated hydroxytoluene; cooking fats and oils; fluorescence; high performance liquid chromatography; hydroquinone; insulin; markets; microextraction; mixing; solvents; statistical analysis; temperature
Abstract:
... The reversed‐phase mode of single drop microextraction has been used as a preparation method for the extraction of some phenolic antioxidants from edible oil samples. Butylated hydroxyl anisole, tert‐butylhydroquinone and butylated hydroxytoluene were employed as target compounds for this study. High‐performance liquid chromatography followed by fluorescence detection was applied for final determi ...
Aloysio da S. Ferrão‐Filho; Daniel de Abreu S. Silva; Taissa A. de Oliveira; Valéria Freitas de Magalhães; Stephan Pflugmacher; Eduardo Mendes da Silva
... Cyanobacteria produce different toxic compounds that affect animal life, among them hepatotoxins and neurotoxins. Because cyanobacteria are able to produce a variety of toxic compounds at the same time, organisms may be, generally, subjected to their combined action. In the present study, we demonstrate the single and combined effects on cladocerans of cyanobacteria that produce microcystins (hepa ...
... Nickel (Ni) and nickel oxide (NiO) nanoparticles (NPs) were successfully synthesized by using a simple, novel and green synthetic route using metal salt and leaves extract of a wild plant “Calotropis gigantea” which act as reducing as well as stabilizing agent due to extra availability of phenolic contents and antioxidants in it. Optimization was carried out by varying different parameters control ...
... Fat-soluble vitamins and antioxidants are of relevance in health and disease. Current methods to extract these compounds from biological fluids mainly need use of multi-steps and multi organic solvents. They are time-consuming and difficult to apply to treat simultaneously large sample number.We here describe a single-step, one solvent extraction of fat-soluble vitamins and antioxidants from biolo ...
... Chitooligosaccharides (COS), as a source of potential bioactive material, has been reported to possess diverse bioactivities. These bioactivities of COS are often tested using relatively poorly characterized oligomer mixtures during past few decades, resulting in difficult identification of COS molecules responsible for biological effects. Therefore, a new interest has recently been emerged on hig ...
... Dietary trans-resveratrol (RES) is rapidly metabolized into sulfated and glucuronated conjugates in humans. This study focused on the in vitro determination of the antioxidant capacity of RES and its main physiological metabolites and on its relevance in vivo. In vitro, RES, RES-3-O-sulfate (R3S) and 3-O-glucuronide (R3G) showed antioxidant activities at a concentration of 1mM when compared to Tro ...