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1. Concurrent infection with porcine reproductive and respiratory syndrome virus and Haemophilus parasuis in two types of porcine macrophages: apoptosis, production of ROS and formation of multinucleated giant cells

Author:
Kavanová, Lenka,   et al.   ; Matiašková, Katarína; Levá, Lenka; Štěpánová, Hana; Nedbalcová, Kateřina; Matiašovic, Ján; Faldyna, Martin; Salát, Jiří;     Show all 8 Authors
Source:
Veterinary research 2017 v.48 no.1 pp. 28
ISSN:
1297-9716
Subject:
giant cells; messenger RNA; Porcine reproductive and respiratory syndrome virus; porcine reproductive and respiratory syndrome; monocytes; respiratory tract diseases; macrophages; inflammation; pathogens; Haemophilus parasuis; cytopathogenicity; mortality; viruses; lungs; mixed infection; bacterial infections; apoptosis; swine
Abstract:
... Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant and economically important infectious diseases affecting swine worldwide and can predispose pigs to secondary bacterial infections caused by, e.g. Haemophilus parasuis. The aim of the presented study was to compare susceptibility of two different types of macrophages which could be in contact with both pathogens du ...
DOI:
10.1186/s13567-017-0433-6
PubMed:
28472979
PubMed Central:
PMC5418695