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- Hashii, Minako, et al. Show all 5 Authors
- Journal of bioscience and bioengineering 2014 v.117 pp. 129-133
- DNA; DNA fragmentation; apoptosis; caspase-3; chromatin; culture media; cultured cells; cytochalasin D; death; endocytosis; lactate dehydrogenase; leukemia; mice; nanoparticles; titanium dioxide
- ... We investigated the effects of nanosized TiO2 particles on the death of mouse leukemia L1210 cells. TiO2 particles suppressed proliferation and induced cell death, as measured by lactate dehydrogenase (LDH) release into the culture medium. Chromatin condensation, which is typical of the initiation of cell death, was observed in approximately 14% cells cultured with titanium dioxide (TiO2) particle ...