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... Cryo-isolation of therapeutic cells such as pancreatic islets has been proposed as a novel new alternative to conventional enzymatic digestion of the pancreas (Taylor, Baicu., Transpl Proc. 43 (2011) 3181–3183. And Cell Transpl. 2013 (In Press)). Apart from avoiding the expense, inconsistencies and toxicity associated with the collagenase-digestion process, cryo-isolation embodies several inherent ...
E. S. C. Camela; R. P. Nociti; V. J. C. Santos; B. I. Macente; G. S. Maciel; M. A. R. Feliciano; W. R. R. Vicente; I. Gill; P. M. Bartlewski; M. E. F. Oliveira
... Spectral Doppler (velocimetric) indices are important indicators of blood perfusion and physiological status of internal organs. Doppler ultrasound is used in andrology to assess the blood flow in the testicular arteries, aiding in the diagnosis of scrotal disorders and abnormal spermatogenesis. It was proposed that blood flow indices measured in the testicular artery, namely, blood flow resistanc ...
... The proliferation of vascular smooth muscle cells (VSMCs) induced by injury to the intima of arteries is an important etiologic factor in vascular proliferative disorders such as atherosclerosis and restenosis. 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside (TSG), an active component extracted from Polygonum multiflorum, has been found to have an antiatherosclerotic effect. The aim of this study ...
... Deposition of lipids in the intima is followed by infiltration of inflammatory cells, like monocytic cells and T lymphocytes, in atherosclerosis. However, roles of lipids in the infiltration of the inflammatory cells are not clearly defined. We investigated the possible involvement of cholesterol or its catabolites in recruitment of monocytic cells. Consumption of a high cholesterol-diet resulted ...
... We attempted to determine the effects of a milieu rich in cholesterol molecules on expression of chemokine CXCL8. A high-cholesterol diet led to an increased transcription of the IL-8 gene in the arteries and elevated levels of CXCL8 in sera of ApoE−/− mice, compared with those of wild-type C57BL/6 mice. Treatment of THP-1 monocyte/macrophage cells with 27-hydroxycholesterol (27OHChol) resulted in ...
... Tissue preparation is the key to a successful MALDI mass spectrometry imaging experiment. A number of different tissue preparations methods have recently been reported for increased sensitivity and/or high spatial resolution analysis. In order to better benchmark these methods in terms of the information content and their suitability for analyzing small tissues containing small but distinct region ...
... With an objective to record the appearance, vascularity changes in umbilicus, placentomes, and blood flow to the uterus, adult (age 5-10 yr) Surti buffalo (parity=2-6; n=24) were inseminated during natural oestrus during the breeding season and scanned by transrectal B mode and colour flow mode ultrasonography every 3-4 days till Day 90 of gestation and then at an interval of 15 days for the compl ...
... During a survey on Myxobolus infection of pond-cultured common carp in Syria three Myxobolus spp. were found. Myxobolus dispar infected the gill arteries, forming large elongated plasmodia in the gill filaments. The plasmodia of M. basilamellaris were located in the gill arches at the base of the filaments. Elongated filiform plasmodia of M. encephalicus were fou ...
... OBJECTIVE: To evaluate the feasibility of a Carrel patch method in feline renal transplantation. STUDY DESIGN: Descriptive case series. ANIMALS: Nine healthy donor cats and 9 client recipient cats with chronic renal failure. METHODS: Renal transplantation was performed in 9 cats with chronic renal failure after collection of a donor's left kidney with a Carrel patch technique. A patch of donor aor ...
... The clinically oriented canine elbow anatomy in its complexity earned a high importance in surgery especially after multiple imaging modalities have been used in the benefit of diagnosis and treatment of canine elbow disorders. The bony, joint, and muscular structures, the arteries, the veins and the nerves supplying the elbow are described and illustrated in textbooks and atlases in the context o ...
RADCLIFFE, CATHERINE H.; WOODIE, J. BRETT; HACKETT, RICHARD P.; AINSWORTH, DOROTHY M.; ERB, HOLLIS N.; MITCHELL, LISA M.; SODERHOLM, L. VINCE; DUCHARME, NORM G.
... To compare upper airway mechanics, arterial blood gases, and tracheal contamination in horses with induced left laryngeal hemiplegia (recurrent laryngeal neuropathy [RLN]) treated by laryngoplasty/vocal cordectomy (LPVC) or modified partial arytenoidectomy (MPA). Repeated measures under the following conditions: Control, RLN, LPVC, and MPA. Six horses. Two trials were conducted under all condition ...
arteries; blood flow; magnetic fields; mathematical models; shear stress
Abstract:
... This paper discuss the biomagnetic fluid aspect of blood flow through narrow tubes with mild stenosis. The blood flow in narrow arteries is treated as two-fluid model with non-Newtonian Jeffrey fluid in the core region and in peripheral region as Newtonian fluid. An analytical solution is obtained for the velocity, volume flow rate, and wall shear stress. The effect of Hartmann number, Jeffrey flu ...
... As the backbone and arteries of a comprehensive transportation network, highways play an important role in improving people’s living standards and promoting economic growth. However, globally, there is limited quantifiable data evaluating the highway traffic state, characteristics, and performance. From the 1960s to the present, remote sensing has been regarded as the most effective technology for ...
... In this study, we present a cat with a common 1‐cm‐long celiacomesenteric trunk. The arteria hepatica branched off first from the separate arteria celiaca and gave rise to the arteria gastrica dextra and arteria gastroduodenalis. The main stem of the arteria celiaca then split into the arteria gastrica sinistra and the arteria lienalis. The arteria mesenterica cranialis extended ventrocaudally in ...
... The adult mammalian heart is minimally regenerative after injury, whereas neonatal hearts fully recover even after major damage. New work from the Red-Horse and Woo labs (Das et al., 2019) shows that collateral artery formation is a key mechanism contributing to successful regeneration in newborn mice and provides insights into how collateral arteries form. ...
... To minimize radial compliance mismatch between native arteries and vascular prostheses over the entire blood pressure range, a biomimetic woven prosthesis sample with a bilayer wall has been developed. Poly(trimethylene terephthalate) (PTT) filaments were used as the circumferential yarns in the inner layer to increase the radial compliance of the inner wall, and poly(ethylene terephthalate) (PET) ...
arteries; biodegradability; carrageenan; crosslinking; doxorubicin; enzymes; hepatoma; hydrophilicity; image analysis; iron oxides; magnetic resonance imaging; microparticles; nanoparticles; sulfates
Abstract:
... Trans-arterial chemoembolization (TACE) has been a mainstream treatment for hepatocellular carcinoma (HCC), accordingly there are more requirements for embolic agents’ properties, mainly concentrated on biodegradability and imaging function. A new kind of biodegradable multifunctional porous microspheres (BMPMs) with internal coarse plications are ingeniously designed and manufactured, consisting ...
... Tropoelastin is the dominant monomer that assembles to form elastin, which confers elasticity to vertebrate elastic tissues including skin, arteries, and lungs. Tropoelastin interacts with cells through cell surface receptors including integrins and glycosaminoglycans (GAGs). As the region 17–18 is recognized as a key region in cell attachment and spreading, we utilized C‐terminal truncated tropoe ...
... Evidence suggests that obesity can contribute to the development of certain complications such as insulin resistance, dyslipidemia, accumulation of visceral fats and cardiovascular dysfunctions. Excess fat also blocks small blood vessels and arteries by accumulating plaque, which increases vascular inflammation, atherosclerosis and risk of stroke and other cardiovascular disease. In 2010, the Worl ...
... Hemodynamic perturbations, partly resulting from abnormal vasoconstriction of digital vessels, have been implicated in the pathogenesis of bovine and equine laminitis. This study compared the responsiveness of isolated bovine (BDA) and equine (EDA) digital arteries to pharmacological agents that stimulate receptor systems involved in the regulation of normal vessel tone. The role of the endotheliu ...
... To test the hypothesis that subarachnoid administration of buprenorphine and lidocaine provides more intense and longer lasting perioperative analgesia with less side effects than xylazine and lidocaine in goats. Randomized, blinded, controlled study. Ten healthy female goats randomly assigned to two groups of five animals each. After sedation with acepromazine (0.1 mg kg⁻¹) intravenously (IV), li ...
... AIMS: To determine if abdominal insufflation with medical air will improve oxygenation and ventilation parameters when compared to insufflation with CO₂ in xylazine-sedated sheep undergoing laparoscopic artificial insemination (AI). METHODS: Forty-seven sheep underwent oestrus synchronisation and were fasted for 24 hours prior to laparoscopic AI. Each animal was randomised to receive either CO₂ or ...
... Blood pressure assessment is valuable during management of chronic conditions with increased risk of developing hypertension and as a standard practice for anesthetic monitoring. Normal arterial blood pressure values have not been well described in megachiropteran species. Following anesthetic induction and maintenance with isoflurane in oxygen, arterial blood pressure was obtained from the poster ...
... Birds are an enigma: their plasma glucose concentration is 1.5–2 times higher than similar-sized mammals, yet they do not normally exhibit symptoms of diabetes. We hypothesized that feeding adult mourning doves a refined carbohydrate diet (white bread: WB) for four weeks would raise plasma glucose concentrations and alter metabolic pathways and endothelial function when compared to birds receiving ...
... While there is strong evidence supporting retinal vascular pattern as a distinctive marker for sheep, it would be advantageous to get an insight into its robustness; in other words, to determine whether retinal recognition of young animals (lambs) can reach as good a matching performance as the one demonstrated for adult sheep. To this aim, a longitudinal study was devised to observe the evolution ...
... We describe a method for the isolation and recirculating perfusion of rabbit livers. Livers were perfused simultaneously through the portal vein and the hepatic artery. Precise descriptions of the surgical preparation, perfusion apparatus and perfusion method are given. The viability of rabbit livers was assessed with the use of physiological, biochemical and histological parameters. We conclude t ...
... Perinatal cerebral ischemia is a major cause of brain damage in the human newborn. Animal models of the brain ischemia provided important roles for extension of the pathophysiological knowledge and evaluating of the efficacy of therapeutic interventions. The purpose of the present study was to introduce a cerebral ischemia model of rabbit neonates which provides useful clues for assessing the isch ...
... Polytetrafluorethylene (PTFE) prostheses were implanted in 12 sheep as a shunt between the carotid artery and the jugular vein using an end-to-side anastomosis technique. This technique allows repeated tests of the pharmacological and toxicological safety of artificial kidney units after both single and multiple administration. Further-more, it enables the investigation of detoxification of compou ...
... Bioengineering approaches have been intensively applied to create small diameter vascular grafts using artificial materials. However, a fully successful, high performing and anti-thrombogenic structure has not been achieved yet. In this study, we present the first step of a process aiming at biofunctionalizing previously designed compliant polyethylene terephthalate (PET) scaffolds (Moreno et al., ...
... The cutaneous distribution and anatomical landmarks of the lateral thoracic artery in the dog are reported. Perfusion studies in cadavers showed a variable distribution, but a skin flap capable of rotation through 90° could be created. The successful use of an axial pattern skin flap based on the lateral thoracic artery for reconstruction of a major skin deficit over the caudal elbow of a Greyhoun ...
EDTA (chelating agent); Western blotting; actin; antibodies; arteries; atherosclerosis; blood serum; confocal microscopy; copper sulfate; cytochalasin D; humans; immunoglobulin G; ionization; ligands; liquid chromatography; low density lipoprotein; macrophages; models; monocytes; oxidants; phagocytosis; phenotype; polyacrylamide gel electrophoresis; polymerization; protein kinase C; staining; tandem mass spectrometry; trypsin
Abstract:
... The human monocyte cell line U937 was differentiated into an adherent macrophage phenotype using phorbol 12-myristate 13-acetate (PMA) to assay the phagocytosis of oxidized low-density lipoprotein (oxLDL) that may play a role in atherosclerosis. Microbeads were coated with the inflammatory ligand oxLDL to create a novel phagocytosis assay that models the binding of macrophages to oxLDL in the soli ...
... The ear vessels in the rabbit appear to be easily accessible for blood puncturing. Several measures are described to overcome problems of vascular spasm and uncontrolled movements of the animal during injection. ...
... Objectives: To investigate the prevalence and progression of murmurs and the development of the left ventricular outflow tract (LVOT) and flow velocities in the great arteries in boxer puppies through adolescence until three years of age. Methods: Nineteen boxer puppies with or without a low‐intensity murmur, but without evidence of congenital heart disease, were studied prospectively. Examination ...
... The assessment of collagen content in tissues is important in biomedical research, since this protein is altered in numerous diseases. Hydroxyproline and Sirius red based assays are the most common methods for collagen quantification. However, these procedures have some pitfalls, such as the requirement of oxygen-free medium or expensive equipment and large sample size or being unsuitable for hydr ...
Markov chain; arteries; data collection; development planning; development projects; models; remote sensing; vegetation types; wetlands; Uganda
Abstract:
... This article reports an assessment of the spatial and temporal loss of wetlands to development projects (DPs) in the Kampala–Mukono Corridor (KMC). Four sets of satellite images (1974–2013), historical and field data sets were used to assess changes in the spatial extent of wetland land cover types. Through unsupervised classification, wetland cover types and DPs were delineated and future wetland ...
... OBJECTIVES: To describe the clinical practice of insertion of arterial catheters in anesthetized dogs and cats, to document complications of arterial catheterization, and to determine risk factors associated with the complications. DESIGN: Prospective clinical study and retrospective evaluation of medical records. SETTING: University teaching hospital. ANIMALS: Dogs (n = 251) and 13 cats anestheti ...
... Our team has previously reported a high strength thermoplastic supramolecular polymer hydrogel. However, the hydrogel required injection temperatures outside the physiological range therefore preventing its use in a living environment. In this article, we reported a thermoresponsive supramolecular copolymer hydrogel p(N-acryloyl glycinamide-co-acrylamide) (PNAGA-PAAm), which can be injected at tem ...
... To investigate relevant indicators of quality of care in a large population-based sample of people with diabetes representative of clinical practice in Italy in 2018.We analyzed data from 11,300,750 subjects. All administrative healthcare claims collected in 2018 were scrutinized to identify subjects with diabetes and investigate several indicators of quality of care. Subjects with diabetes were i ...
... Cryosurgery is evolving from a focal therapy for cancer to one that can also treat cardiovascular and neural targets. For example, new focal therapeutic targets include the pulmonary vein (atrial fibrillation), arteries (renal denervation) and nerves (pain and plantar fasciitis). For cryosurgery to successfully compete with heat or other ablative technologies in these new targets, it will be neces ...
... Abnormal levels of High temperature requirement A1 (HtrA1) protein have been repeatedly observed in sera and placentas of preeclampsia patients. To understand the functions of HtrA1 in placentation and in the etiology of preeclampsia, we established HtrA1⁻/⁻ mice. HtrA1⁻/⁻ mice show intrauterine growth retardation, and their placentas are small due to a reduced size of the junctional zone and aber ...
... The Eya1 gene encodes a transcriptional co-activator that acts with Six1 to control the development of different organs. However, Six1-Eya1 interactions and functional roles in mesenchymal cell proliferation and differentiation as well as alveolarization during the saccular stage of lung development are still unknown. Herein, we provide the first evidence that Six1 and Eya1 act together to regulat ...
... Incomplete endothelialization and neointimal hyperplasia of injured arteries can cause acute and late stent thromboses. This work develops hybrid stent/biodegradable nanofibers for the local and sustained delivery of rosuvastatin to denuded artery walls. Biodegradable nanofibers were firstly prepared by dissolving poly(D,L)-lactide-co-glycolide and rosuvastatin in 1,1,1,3,3,3-hexafluoro-2-propanol ...
... Two beef steers accidentally injected into a branch of the auricular artery with an oil-based formulation of ceftiofur died within 5 minutes of injection. Notable pathologic findings included distention and obstruction of cerebral and cerebellar arteries by a whitish tan material and hemorrhages within meningeal spaces, the choroid plexus, cerebrum, and cerebellum. Lipid material was identified wi ...
... To compare the accuracy of a 3rd (Dolphin Voyager) versus 1st generation pulse oximeter (Nellcor N-180). Prospective laboratory investigation. Eight adult dogs. In anesthetized dogs, arterial oxygen saturation (SpO₂) was recorded simultaneously with each pulse oximeter. The oxygen fraction in inspired gas (FiO₂) was successively reduced from 1.00 to 0.09, with re-saturation (FiO₂ 0.40) after each ...
... Canadian physical activity guidelines recommend older adults accumulate 150 min of weekly moderate to vigorous physical activity (MVPA). Older adults who are insufficiently active may have reduced blood vessel health and an increased risk of cardiovascular disease. We tested this hypothesis in 11 older adults who did (7 female; age, 65 ± 5 years; MVPA, = 239 ± 81 min/week) and 10 older adults who ...
... The recent identification of acid sensing ion channels (ASICs) in vascular beds suggests their possible involvement in modulating vasomotor tone. Therefore, we investigated the gene expression profiles of ASIC subtypes in the middle cerebral artery (MCA) of Wistar rats and the functional implication of ASICs in acidosis-induced relaxation as well as maintenance of resting tension.Real time PCR was ...
... The objectives of this research were to evaluate the effects of thermal panting in domestic turkeys on arterial blood values for the acid-base variables, pHa, bicarbonate concentration ([HCO⁻ ₃]a), partial pressure of carbon dioxide (PaCO₂), and hemoglobin concentration [Hb]. In addition, body temperature and partial pressure of oxygen (PaO₂) were measured to determine the effectiveness of panting ...
... The comparative study of the acid-base balance (ABB) parameters has been performed on 20 clinically healthy mature Małopolski horses. An arterial blood sample from the facial artery and a sample of venous blood from the external cervical vein were colected from each animal. In the samples tested, the blood pH, pCO₂, tCO₂, HCO₃⁻, concentration of Na⁺, K⁺, Cl⁻, and a value of the anion gap were dete ...
... Immunohistochemical and ultrastructural studies were conducted on the gills of gilthead seabream, Sparus aurata L., naturally infected with the copepod ectoparasite Ergasilus lizae (Krøyer, 1863) in order to assess pathology and the host immune cell response. Gills of 56 gilthead seabream were screened for ectoparasites; 36 specimens (64.3%) harbored E. lizae. Intensity of infection was 32.7±8.7 ( ...
... The inner surfaces of arteries and veins are naturally anti-thrombogenic, whereas synthetic materials placed in blood contact commonly experience thrombotic deposition that can lead to device failure or clinical complications. Presented here is a bioinspired strategy for self-cleaning anti-thrombotic surfaces using actuating surface topography. As a first test, wrinkled polydimethylsiloxane planar ...
... BACKGROUND: Recent research suggests that central pulse pressure may be a better indicator of cardiovascular disease outcomes than brachial pressure. Little information is available regarding the effect of food intake on postprandial central pressure and other measures of arterial stiffness when measured with a noninvasive pulse wave analysis (PWA) technique. OBJECTIVE: The objective was to invest ...
... BACKGROUND: High-fat meals have negative effects on endothelial function, but vitamin-rich side orders may prevent these negative effects. OBJECTIVE: The acute effects of conventional and alternative fast-food meals on vascular function and various cardiovascular biomarkers were investigated. DESIGN: In a crossover study, flow-mediated endothelium-dependent dilatation (FMD) and cardiovascular dise ...
... OBJECTIVE: To describe acute mesenteric infarction due to suspected Spirocerca lupi aberrant migration in 5 dogs. CASE SERIES SUMMARY: All dogs were large breed, none of which exhibited typical clinical signs associated with spirocercosis. All dogs were eventually diagnosed with septic peritonitis. On exploratory laparotomy, thickening of the jejunal arteries, surrounding mesojejunum, and segmenta ...
... A hypercoagulable condition and poor perfusion to distal extremities might occur during equine endotoxaemic or septic shock, which could cause thrombosis of limb arteries. In our review, thrombosis occurred in neonatal foals in association with Gram‐negative bacteraemia. In 3 olderfoals and adults, thrombosis was associated with inflammatory bowel disease, diarrhoea and toxaemia. All patients had ...
... Quercetin (Q) reduces blood pressure (BP) in hypertensive individuals, but the mechanism is unknown. We hypothesized that acute Q aglycone administration reduces BP in hypertensive men by decreasing angiotensin-converting enzyme (ACE) activity and/or by lowering the ratio of circulating endothelin-1 (ET-1) to nitric oxide and that these alterations will improve endothelial function. Using a double ...
... Objectives: Adiponectin is an adipocyte-derived collagen-like protein, highly specific to adipose tissue and may represent an important link between obesity and atherosclerosis. The present study was designed to investigate a possible association between serum adiponectin levels and early vascular changes in obese patients as determined by intima media thickness (IMT) and arterial pulse-wave conto ...
... Despite the role of melatonin in the regulation of the sleep-wake cycle and seasonal-reproduction, the present study investigated, for the first time, the potential role of melatonin on testicular blood flow (TBF) in goats. Twelve sexually mature male Shiba goats were exposed to a single s.c. injection of either melatonin suspended in one ml of corn oil (melatonin group; 36 mg/goat; n = 5) or one ...
... Radioligand binding studies and functional assays on isolated smooth muscle preparations were performed in order to obtain a biochemical and functional characterization of the beta-adrenoceptor (beta-AR) subtypes involved in regulation of the smooth muscle relaxation of the calf's common digital artery. The results indicate that the common digital artery possesses two beta-AR populations (40% beta ...
... The standard of today's reptile practice calls on clinicians to use an ever-increasing array of diagnostic tools to gather information and obtain a definitive diagnosis. Few, if any, pathognomonic signs exist for reptile diseases, and for most clinical syndromes there is a lack of information regarding pathophysiology for one to define standard therapeutic protocols based solely on clinical signs ...
... Resistance arteries have been implicated as a major contributing factor in the sequela of disease conditions such as hypertension and diabetes and, as such, are a major focus of cardiovascular research. The paracrine influence of the intimal endothelial layer of resistance arteries is well established. Considering the growing body of evidence substantiating a functionally relevant vascular adventi ...
Hui Ying Ang; Gordon Minru Xiong; Su Yin Chaw; Jie Liang Phua; Jaryl Chen Koon Ng; Philip En Hou Wong; Subbu Venkatraman; Tze Tec Chong; Yingying Huang
arteries; catheters; females; in vivo studies; inflammation; mixed breeds; paclitaxel; pharmacokinetics; rapamycin; swine; therapeutics
Abstract:
... Endovascular therapy in peripheral intervention has grown exponentially in the past decade, but the issue of high restenosis rates in lower extremity arteries still persist. While drug-coated balloons (DCB) have been the device of choice, recent controversary regarding the long-term safety of paclitaxel have raised concern over current DCBs. In our study, we proposed that the direct injection of a ...
... Existing experimental data do not sufficiently explain which pathophysiologic processes are involved in different age of rats exposed to long-term particulate matter. This study explored the pulmonary and cardiovascular effects of long-term PM₂.₅ and PM₁₀ exposure in juvenile, adult and senescent rats. Tail cuff plethysmography, whole-body plethysmographic system, myograph, enzyme-linked immunosor ...
... Ethnopharmacological relevance: Leaf and seed decoctions of Casimiroa spp. are used in Mexican traditional medicine to treat high blood pressure. Previous researches showed as Casimiroa extracts are able to induce relaxation of rat aortic and caudal arteries. To study the influence of the aging, we determined the vascular effect induced by extracts of Casimiroa edulis and Casimiroa pubescens in ar ...
... Citrus by-products are rich in flavanone aglycons which have lower bioactivity than aglycone forms. Based on this, the study evaluated the effects of enzyme biotransformation on antioxidant and vasorelaxant capacity of polyphenolic rich-extracts from citrus waste. Enzymatic treatment produced extracts with high hesperetin concentrations and higher antioxidant capacity than non-treated extracts. At ...
... Objective To evaluate the agreement between invasive blood pressure (IBP) and Doppler ultrasound blood pressure (DUBP) using three cuff positions and oscillometric blood pressure (OBP) in anesthetized dogs. Study design Prospective study. Animals Nine adult dogs weighing 14.5–29.5 kg. Methods The cuff was placed above and below the tarsus, and above the carpus with the DUBP and above the carpus wi ...
... To determine agreement between invasive blood pressures measured in three peripheral arteries in anaesthetized horses undergoing elective surgery.Prospective balanced incomplete block design.A total of 18 client-owned horses.Invasive blood pressure (IBP) was measured simultaneously in one of the following three combinations: 1) transverse facial and facial artery; 2) transverse facial and metatars ...
adhesion; adhesives; animal experimentation; animal models; arteries; chemistry; hemostasis; in vivo studies; kidneys; neoplasms; osteotomy; polypeptides; rabbits; rats; swine
Abstract:
... A series of hyperbranched, thermo-responsive and mussel-inspired polypeptides were synthesized and used for surgical adhesion, hemostasis and interventional embolization. These polypeptides showed excellent tissue-adhesive properties according to adhesive strength tests on porcine skin and bone in vitro, where the maximum lap-shear adhesion strength on porcine skin was 114.5 kPa and the maximum te ...
... The goal of our study was to reveal the important mechanism(s) responsible for the enhanced contractility of isolated arteries from animals suffering genetic hypertension.Contractile force of endothelium-denuded arteries, modulated by various interventions, was measured by wire myography.Spontaneously hypertensive rat (SHR) and Wistar-Kyoto rat (WKY) arteries were stimulated by norepinephrine, inc ...
... Obesity is a risk factor for endothelial dysfunction, the severity of which is likely to vary depending on extent and impact of adiposity on the vasculature. This study investigates the roles of cyclooxygenase isoforms and thromboxane receptor activities in the differential endothelial dilatory capacities of arteries derived from omental and subcutaneous adipose tissues in obesity.Small arteries w ...
... Aim of the study: Eucommia ulmoides Oliv. leaf is a traditional Chinese medicine that exhibits an anti-diabetic action. This study was designed to investigate whether long-term administration of Eucommia ulmoides Oliv. leaves extract (ELE) ameliorates pre-diabetic state of insulin resistance and abnormal perivascular innervation in the hyperinsulinemic state. Materials and methods: ELE at doses of ...
... The FAM20 family of secreted proteins consists of three members (FAM20A, FAM20B, and FAM20C) recently linked to developmental disorders suggesting roles for FAM20 proteins in modulating biomineralization processes. The authors report here findings in knockout mice having null mutations affecting each of the three FAM20 proteins. Both Fam20a and Fam20c null mice survived to adulthood and showed bio ...
... Most urgent health problems are related to a blood vessel formation failure. The use of stem cells from different sources or species for both in vitro and in vivo engineering of endothelium does not necessarily imply their direct commitment towards a vascular phenotype. In the present study, we used human amniotic fluid stem cells (AFSC) to evoke a strong angiogenic response in murine recipients, ...
... The aim of this study was to describe the changes in the resistance index (RI) and systolic/diastolic ratio (S/D) of the uterine arteries during mid-pregnancy abortion induction in the dog. Sixteen 30-35 day pregnant bitches were randomly assigned to either a pharmacological protocol to interrupt gestation (n = 8) or were used as untreated control group (n = 8). Doppler assessments of uterine arte ...
Canis lupus; Cerdocyon thous; arteries; blood; dogs; innervation; muscles; surgery; South America
Abstract:
... The crab‐eating fox (Cerdocyon thous) is a wild canid distributed throughout South America. It is one of the wild canids reported being hit by vehicles and injured in snares, thus inducing trauma or injury to the musculoskeletal system, possibly occurring in the brachial region. The main objective of this research was to provide an anatomic description of the crab‐eating fox's intrinsic brachial m ...
... Recent studies have highlighted cities as prime locations for the introduction, establishment, and spread of non‐native and invasive species. As the hydrological arteries of cities, urban river corridors have an important role to play in influencing species invasions. This overview examines existing literature to consider (a) how the landscape functions of urban river corridors (habitat, conduit, ...
... In this study, monofilament tubular braided structures were fabricated and their performances were analyzed. The braided tubes are in three-dimensional form, made of polyester monofilaments intended for use in medical applications. This type of structure, called a stent, is used to open clogged arteries and veins by exerting radial forces. The radial force of a braided tube basically depends on th ...
... Atherosclerosis is one of the most frequent etiology for myocardial infarction and death. It is also the main cause of angina pectoris, a perceived symptom that results of a mismatch between myocardial supply and demand, caused by the partial obstruction of the arteries. The correct diagnosis of atherosclerosis can led to a reduction of mortality. In this research, the phospholipids profile of ser ...
... The anatomy of the internal carotid and maxillary arteries was examined using angiography, subtraction angiography and arterial cast preparations in three horses. Subtraction angiography was superior to angiography in demonstrating the anatomy of the occipital, external ophthalmic, ethmoidal and palatine arteries. In three horses manipulation of the internal carotid and occipital arteries during a ...
Peres Ferraz de Melo, A.; de Souza, W. Machado; Rodrigues, R. Felipe; Alves, F. Ribeiro; Rici, R. Eli Graci; Guerra, R. Romão; Favaron, P. Oliveira; Miglino, M. Angélica; Di Dio, L. John Aphonso
... With 2 figures SUMMARY: The anatomosurgical segmentation of the arteries of the spleen was studied in 31 deer of the species Mazama gouazoubira and Blastocerus dichotomus by means of vascular injection with latex and vinyl acetate and radiographic examination. The arteria lienalis penetrated through the hilus lienis in 87% of the cases, whereas an extrahilar artery was present in the other cases. ...
... With 6 figures and 2 tables SUMMARY: Intrarenal anatomy was studied in detail to evaluate how useful rabbits could be as a urologic model. Only one renal artery was observed, which was divided into dorsal and ventral branches in all cases. Three segmental arteries (cranial, mesorenal and caudal) was the most frequent branching pattern found in both the dorsal and ventral division. There was an imp ...
... The present study aimed to show the arterial blood supply of the udder of the Egyptian native breed of goat (Baladi goat) to be used as a guide during mastectomy and other surgical interferences. The study was carried out on the udder of twelve apparently healthy adult female Egyptian Baladi goats. Four goats were used for mastectomy, one specimen was used for radiography and the other specimens w ...
... The aim of this study was to describe origin, localisation and variations of renal arteries and veins in the rabbit. The study was carried out on 40 adult European rabbits. We prepared corrosion casts of the rabbit arterial and venous system. Spofacryl was used as the casting medium. In 75% of cases the origin of arteriae renales was located at the level of the third lumbar vertebra and in remaini ...
... Histological and corrosive studies of 75 bovine testes were focused on the vascular complex of the tunica albuginea. Thanks to used MultiScanBase v.14.02 software arterial and venous vessels and also vascular anastomoses were analyzed preciously. The studies revealed the superficial layer containing vessels of smaller diameter and reduced wall structure and the deeper layer with wider, winding ves ...
... A thorough knowledge about anastomoses between uterine and ovarian arteries could have great impact in surgical interventions. The present study aimed to use an angiographic procedure to show the vascular relationship between uterus and ovaries, possible anastomoses between uterine arteries during pregnancy, blood supply to gestational sacs, and the vascular pattern in the uterus of a bitch with p ...
... AIMS: Rheumatoid arthritis (RA) is associated with high cardiovascular mortality. Impaired endothelial cell (EC) function and elevated angiotensin II levels may be central to the link between vascular dysfunction and RA. Here we investigated the action of angiotensin type 1 receptor (AT1R) blockade on endothelium-dependent relaxation of the isolated saphenous artery in a rat model of monoarthritis ...
... Atherosclerosis is the predominant underlying pathology of many types of cardiovascular disease and is one of the leading causes of death worldwide. It is characterized by the retention of oxidized low-density lipoprotein (ox-LDL) in lipid-rich macrophages (foam cells) in the intima of arteries. Autoantigens derived from oxLDL can be used to vaccinate against atherosclerosis. However, a major chal ...
... We aimed to investigate the anti-hypertensive effect of radiofrequency (RF) renal denervation (RDN) in an animal model of hypertension.RF energy was delivered to bilateral renal arteries through a 2Fr catheter with opening abdomen in 8 spontaneously hypertensive rats (SHRs) and 8 Wistar–Kyoto rats (WKYs). Sham operation was performed in other 8 SHRs and 8 WKYs. Blood pressure (BP), heart rate (HR) ...
... Aim of the study: To investigate the antihypertensive fractions of Eucommia ulmoides Oliv. and their underlying mechanisms in spontaneously hypertensive rats (SHRs). Materials and methods: In vivo study, Eucommia ulmoides lignans (EuL) and Eucommia ulmoides iridoids (EuI) were administrated to Sprague-Dawley (SD) rats and SHRs, and their blood pressures were measured. Plasma level of nitric oxide ...
... To observe antinociceptive, cardiopulmonary and sedative effects of five different 12-hour lidocaine infusions in conscious dogs, and measure plasma lidocaine concentrations. Two-part randomized, prospective, blinded, cross-over experimental study. Six neutered male, crossbred dogs approximately 1-2 years of age and weighing 29.1 ± 4.0 kg. Dogs received lidocaine [2 mg kg⁻¹, intravenous (IV)] or e ...