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1. Development of the blood supply to the growth cartilage of the medial femoral condyle of foals

Author:
Bjørn H. Wormstrand; Cathrine T. Fjordbakk; David J. Griffiths; Sigrid Lykkjen; Kristin Olstad
Source:
Equine veterinary journal 2021 v.53 no.1 pp. 134-142
ISSN:
0425-1644
Subject:
age; arteries; bacteria; barium; blood; branching; cartilage; experimental design; fetus; foals; infection; micro-computed tomography; objectives; osteochondrosis; osteomyelitis; pregnancy; supply
Abstract:
... BACKGROUND: Growth cartilage is found in the articular‐epiphyseal cartilage complex (AECC) and the physis. It has a temporary blood supply organised as end arteries. Vascular failure is associated with osteochondrosis, but infection can also obstruct vessels. The location of bacteria was recently compared to arterial perfusion, and the results indicated that they were located in the distal tips of ...
DOI:
10.1111/evj.13256

2. Direct assessment of very-low-density lipoprotein by mass sensitive sensor with molecularly imprinted polymers

Author:
Suticha Chunta; Worachote Boonsriwong; Panwadee Wattanasin; Wanpen Naklua; Peter A. Lieberzeit
Source:
Talanta 2021 v.221 pp. 121549
ISSN:
0039-9140
Subject:
acrylamides; arteries; assays; biomimetics; blood serum; cholesterol; chylomicrons; colorimetry; coronary disease; cross reaction; cross-linking reagents; detection limit; estimation; high density lipoprotein; lead; low density lipoprotein; mass; particles; polymers; pretreatment; quartz crystal microbalance; repeatability; reproducibility; triacylglycerols; very low density lipoprotein
Abstract:
... Very-low-density lipoprotein (VLDL) contributes to the buildup of atherosclerotic plaque in the arteries and can lead to coronary heart disease. In clinical laboratory testing, the cholesterol content of VLDL (VLDL-C) cannot be assessed directly by the enzymatic colorimetric assay as it can for other lipoproteins, due to lack of a specific sample pretreatment technique. VLDL concentration relies o ...
DOI:
10.1016/j.talanta.2020.121549

3. Passage of spermatozoa through the epididymis of the boar (Sus scrofa domesticus)

Author:
F. Hassan; W. Holtz
Source:
Theriogenology 2021 v.161 pp. 126-130
ISSN:
0093-691X
Subject:
Sus scrofa; arteries; boars; caput epididymidis; castration; cauda epididymidis; corpus epididymidis; ductus deferens; miniature swine; sperm transport; spermatozoa; thymidine
Abstract:
... Previous studies of epididymal transit in the pig have had insufficient animal numbers to provide a comprehensive picture of a continuous process. The present study attempts to addresses this issue. Radioactively labeled thymidine was infused into the testicular arteries of 48 sexually rested young adult boars of the Goettingen Miniature Pig breed. Hemicastrations were performed in random order in ...
DOI:
10.1016/j.theriogenology.2020.11.024

4. 48 Transrectal color Doppler evaluation of umbilicus, placentomes, and uterine vascularity changes throughout pregnancy in Surti buffalo

Author:
M. Gaur; G. N. Purohit
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 149
ISSN:
1031-3613
Subject:
adults; arteries; blood flow; breeding season; buffaloes; color; estrus; placenta; pregnancy; ultrasonography; umbilical cord; umbilicus; uterus
Abstract:
... With an objective to record the appearance, vascularity changes in umbilicus, placentomes, and blood flow to the uterus, adult (age 5-10 yr) Surti buffalo (parity=2-6; n=24) were inseminated during natural oestrus during the breeding season and scanned by transrectal B mode and colour flow mode ultrasonography every 3-4 days till Day 90 of gestation and then at an interval of 15 days for the compl ...
DOI:
10.1071/RDv32n2Ab48

5. A biodegradable multifunctional porous microsphere composed of carrageenan for promoting imageable trans-arterial chemoembolization

Author:
Liu Kunliang; Jin Zhicheng; Hu Xiaolong; Yan Dan; Zhang Yu; Zhu Haidong; Teng Gaojun; Xiong Fei
Source:
International journal of biological macromolecules 2020 v.142 pp. 866-878
ISSN:
0141-8130
Subject:
arteries; biodegradability; carrageenan; crosslinking; doxorubicin; enzymes; hepatoma; hydrophilicity; image analysis; iron oxides; magnetic resonance imaging; microparticles; nanoparticles; sulfates
Abstract:
... Trans-arterial chemoembolization (TACE) has been a mainstream treatment for hepatocellular carcinoma (HCC), accordingly there are more requirements for embolic agents’ properties, mainly concentrated on biodegradability and imaging function. A new kind of biodegradable multifunctional porous microspheres (BMPMs) with internal coarse plications are ingeniously designed and manufactured, consisting ...
DOI:
10.1016/j.ijbiomac.2019.10.026

6. A four-week white bread diet does not alter plasma glucose concentrations, metabolic or vascular physiology in mourning doves, Zenaida macroura

Author:
Anthony J. Basile; Paniz Jasbi; William Clark; Xiaojian Shi; Haiwei Gu; Pierre Deviche; Karen L. Sweazea
Source:
Comparative biochemistry and physiology 2020 v.247 pp. 110718
ISSN:
1095-6433
Subject:
Zenaida macroura; adults; arteries; biochemical pathways; blood; blood glucose; diabetes; diet; doves; glycogen; insulin; liver; mammals; metabolites; metabolomics; muscles; principal component analysis; tibia; uric acid; vasodilation; white bread
Abstract:
... Birds are an enigma: their plasma glucose concentration is 1.5–2 times higher than similar-sized mammals, yet they do not normally exhibit symptoms of diabetes. We hypothesized that feeding adult mourning doves a refined carbohydrate diet (white bread: WB) for four weeks would raise plasma glucose concentrations and alter metabolic pathways and endothelial function when compared to birds receiving ...
DOI:
10.1016/j.cbpa.2020.110718

7. A view on the quality of diabetes care in Italy and the role of Diabetes Clinics from the 2018 ARNO Diabetes Observatory

Author:
Enzo Bonora; Salvatore Cataudella; Giulio Marchesini; Roberto Miccoli; Olga Vaccaro; Gian Paolo Fadini; Nello Martini; Elisa Rossi
Source:
Nutrition, metabolism, and cardiovascular diseases 2020 v.30 no.11 pp. 1945-1953
ISSN:
0939-4753
Subject:
agonists; albuminuria; arteries; cardiovascular diseases; cholesterol; creatinine; diabetes; disease surveillance; eyes; frequency; glucagon-like peptide 1; glycemic effect; guidelines; health care workers; health services; hospitals; lipid composition; metabolism; monitoring; nutrition; sodium glucose cotransporter-2 inhibitors; ultrasonography; Italy
Abstract:
... To investigate relevant indicators of quality of care in a large population-based sample of people with diabetes representative of clinical practice in Italy in 2018.We analyzed data from 11,300,750 subjects. All administrative healthcare claims collected in 2018 were scrutinized to identify subjects with diabetes and investigate several indicators of quality of care. Subjects with diabetes were i ...
DOI:
10.1016/j.numecd.2020.08.018

8. Administration of melatonin improves testicular blood flow, circulating hormones, and semen quality in Shiba goats

Author:
Haney Samir; Paul Nyametease; Mohamed Elbadawy; Kentaro Nagaoka; Kazuaki Sasaki; Gen Watanabe
Source:
Theriogenology 2020 v.146 pp. 111-119
ISSN:
0093-691X
Subject:
arteries; blood flow; corn oil; enzyme immunoassays; estradiol; follicle-stimulating hormone; goats; inhibin; insulin-like growth factor I; luteinizing hormone; male fertility; males; melatonin; monitoring; nitric oxide; radioimmunoassays; semen quality; sexual maturity; spermatozoa; testes; testosterone; ultrasonography
Abstract:
... Despite the role of melatonin in the regulation of the sleep-wake cycle and seasonal-reproduction, the present study investigated, for the first time, the potential role of melatonin on testicular blood flow (TBF) in goats. Twelve sexually mature male Shiba goats were exposed to a single s.c. injection of either melatonin suspended in one ml of corn oil (melatonin group; 36 mg/goat; n = 5) or one ...
DOI:
10.1016/j.theriogenology.2020.01.053

9. Adventitial injection delivery of nano-encapsulated sirolimus (Nanolimus) to injury-induced porcine femoral vessels to reduce luminal restenosis

Author:
Hui Ying Ang; Gordon Minru Xiong; Su Yin Chaw; Jie Liang Phua; Jaryl Chen Koon Ng; Philip En Hou Wong; Subbu Venkatraman; Tze Tec Chong; Yingying Huang
Source:
Journal of controlled release 2020 v.319 pp. 15-24
ISSN:
0168-3659
Subject:
arteries; catheters; females; in vivo studies; inflammation; mixed breeds; paclitaxel; pharmacokinetics; rapamycin; swine; therapeutics
Abstract:
... Endovascular therapy in peripheral intervention has grown exponentially in the past decade, but the issue of high restenosis rates in lower extremity arteries still persist. While drug-coated balloons (DCB) have been the device of choice, recent controversary regarding the long-term safety of paclitaxel have raised concern over current DCBs. In our study, we proposed that the direct injection of a ...
DOI:
10.1016/j.jconrel.2019.12.031

10. Age differences in the pulmonary and vascular pathophysiologic processes after long-term real-time exposure to particulate matter in rats

Author:
Xue Xiao; Tong Yao; Shuaishuai Du; Junxia Zhang; Tingting Huang; Yali Lei; Lei Cao; Zhenxing Shen; Yongxiao Cao
Source:
Chemosphere 2020 v.261 pp. 127710
ISSN:
0045-6535
Subject:
adults; age; air; arteries; atomic absorption spectrometry; blood pressure; blood serum; body weight; cadmium; chromium; cytokines; enzyme-linked immunosorbent assay; exposure duration; heavy metals; juveniles; kidneys; lead; liver; lung function; lungs; particulates; pathophysiology; rats; survival rate; tail; vasodilation
Abstract:
... Existing experimental data do not sufficiently explain which pathophysiologic processes are involved in different age of rats exposed to long-term particulate matter. This study explored the pulmonary and cardiovascular effects of long-term PM₂.₅ and PM₁₀ exposure in juvenile, adult and senescent rats. Tail cuff plethysmography, whole-body plethysmographic system, myograph, enzyme-linked immunosor ...
DOI:
10.1016/j.chemosphere.2020.127710

11. Aglycone-rich extracts from citrus by-products induced endothelium-independent relaxation in isolated arteries

Author:
Amanda Roggia Ruviaro; Paula de Paula Menezes Barbosa; Eduardo Costa Alexandre; Alberto Fernando Oliveira Justo; Edson Antunes; Gabriela Alves Macedo
Source:
Biocatalysis and agricultural biotechnology 2020 v.23 pp. 101481
ISSN:
1878-8181
Subject:
Citrus; antihypertensive effect; antioxidant activity; antioxidants; arteries; biotransformation; byproducts; citrus juices; enzymatic treatment; fruit extracts; hesperetin; new products; oxidation; oxidative stress; pectins; vasodilator agents; wastes
Abstract:
... Citrus by-products are rich in flavanone aglycons which have lower bioactivity than aglycone forms. Based on this, the study evaluated the effects of enzyme biotransformation on antioxidant and vasorelaxant capacity of polyphenolic rich-extracts from citrus waste. Enzymatic treatment produced extracts with high hesperetin concentrations and higher antioxidant capacity than non-treated extracts. At ...
DOI:
10.1016/j.bcab.2019.101481

12. Apelin inhibits an endothelium-derived hyperpolarizing factor-like pathway in rat cerebral arteries

Author:
Amreen Mughal; Santo Anto; Chengwen Sun; Stephen T. O’Rourke
Source:
Peptides 2020 v.132 pp. 170350
ISSN:
0196-9781
Subject:
antagonists; arteries; catalytic activity; cytochrome P-450; endothelial nitric oxide synthase; enzyme inhibitors; guanylate cyclase; myocytes; nitric oxide; peptides; prostacyclin; prostaglandin synthase; rats; serotonin; smooth muscle; vasoconstriction; vasodilation
Abstract:
... Apelin has complex vasomotor actions inasmuch as the peptide may cause either vasodilation or vasoconstriction depending on the vascular bed and experimental conditions. In cerebral arteries, apelin inhibits endothelium-dependent relaxations mediated by nitric oxide (NO); however, its effects on relaxation to other endothelium-derived substances (e.g. prostacyclin, endothelium-derived hyperpolariz ...
DOI:
10.1016/j.peptides.2020.170350

13. Assessment of Dog Testis Perfusion by Colour and Pulsed-Doppler Ultrasonography and Correlation With Sperm Oxidative DNA Damage

Author:
Helena Lemos; Jesus Dorado; Manuel Hidalgo; Isabel Gaivão; Ana Martins-Bessa
Source:
Topics in companion animal medicine 2020 v.41 pp. 100452
ISSN:
1938-9736
Subject:
DNA damage; arteries; blood flow; color; comet assay; diagnostic techniques; dogs; males; medicine; pets; sperm concentration; sperm quality; testes; ultrasonography
Abstract:
... The assessment of testicular artery blood flow by colour and pulsed-Doppler ultrasonography is an important diagnostic technique to assess vascular perfusion. Recently, it has been suggested as a good predictor of sperm quality. On the other hand, through the alkaline Comet Assay, it is possible to quantify sperm oxidative DNA damage. The aim of this study was to evaluate the relationship between ...
DOI:
10.1016/j.tcam.2020.100452

14. Association between abdominal fat distribution and coronary plaque instability in patients with acute coronary syndrome

Author:
Kozo Okada; Kiyoshi Hibi; Yasuhiro Honda; Peter J. Fitzgerald; Kouichi Tamura; Kazuo Kimura
Source:
Nutrition, metabolism, and cardiovascular diseases 2020 v.30 no.7 pp. 1169-1178
ISSN:
0939-4753
Subject:
abdominal fat; adipose tissue; arteries; cardiovascular diseases; computed tomography; lipid content; lipids; metabolism; obesity; patients; regression analysis; subcutaneous fat; ultrasonics
Abstract:
... This study aimed to assess possible association of detailed abdominal fat profiles with coronary plaque characteristics in patients with acute coronary syndrome (ACS).In 60 patients with ACS, culprit arteries were evaluated at 1-mm intervals (length analyzed: 66 ± 28 mm) by grayscale and integrated backscatter intravascular ultrasound (IB-IVUS) before percutaneous coronary intervention. Standard I ...
DOI:
10.1016/j.numecd.2020.03.017

15. Biglycan and atherosclerosis: Lessons from high cardiovascular risk conditions

Author:
Michele Scuruchi; Francesco Potì; Javier Rodríguez-Carrio; Giuseppe Maurizio Campo; Giuseppe Mandraffino
Source:
Biochimica et biophysica acta 2020 v.1865 no.2 pp. 158545
ISSN:
1388-1981
Subject:
arteries; atherosclerosis; childhood; chondroitin sulfate; dermatan sulfate; diabetes; extracellular matrix; hyperlipidemia; hypertension; kidney diseases; lipoproteins; proteoglycans; risk factors; smoking (habit)
Abstract:
... Atherosclerosis (ATH) is a chronic, dynamic, evolutive process involving morphological and structural subversion of artery walls, leading to the formation of atherosclerotic plaques. ATH generally initiates during the childhood, occurring as a result of a number of changes in the intima tunica and in the media of arteries. A key event occurring during the pathobiology of ATH is the accumulation of ...
DOI:
10.1016/j.bbalip.2019.158545

16. Cerebral Computed Tomography Scan Demonstrating Ischemic Stroke in a Filly After Intravenous Antibiotic Administration

Author:
Guillaume Saliou; Xavier d’Ablon; Marie Théaudin; Tangi Saliou; Simon Bourassi
Source:
Journal of equine veterinary science 2020 v.88 pp. 102953
ISSN:
0737-0806
Subject:
adverse effects; anaphylaxis; anesthesia; antibiotics; antibodies; arteries; computed tomography; equipment; fillies; foals; hemodynamics; hypotension; image analysis; immunoglobulin E; infarction; intravenous injection; ischemia; stroke; visual cortex; watersheds
Abstract:
... Performing a brain computerized tomography scan (CT scan) on a foal requires specific equipment and anesthesia for large animals. However, the information obtained may demonstrate lesions responsible for the neurological deficits. Especially, CT scan findings may help to understand a mechanism of cerebral ischemia. Indeed, categories of cerebral ischemia are divided in three types: territorial inf ...
DOI:
10.1016/j.jevs.2020.102953

17. Changes in expression of prostaglandin synthase in ovine liver during early pregnancy

Author:
Ling Yang; Xu Han; Leying Zhang; Ning Li; Zimo Zhao; Jiachen Bai
Source:
Canadian journal of animal science 2020 v.100 no.3 pp. 432-439
ISSN:
1918-1825
Subject:
Western blotting; aldo-keto reductases; arteries; endothelial cells; estrous cycle; ewes; hepatocytes; immune response; immune system; immunohistochemistry; liver; messenger RNA; pregnancy; prostaglandin synthase; prostaglandin-E synthase; prostaglandin-F synthase; prostaglandins; proteins; quantitative polymerase chain reaction
Abstract:
... Liver can function as part of the innate and adaptive immune systems. We hypothesize that prostaglandins participate in the regulation of hepatic immune function during early pregnancy in sheep. The objective of this study was to elucidate expression of prostaglandin synthase in ovine liver during early pregnancy. Ovine livers were sampled on day 16 of the estrous cycle, and days 13, 16, and 25 of ...
DOI:
10.1139/cjas-2019-0171

18. Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

Author:
Ilaria Del Gaudio; Ivana Sreckovic; Pablo Zardoya-Laguardia; Eva Bernhart; Christina Christoffersen; Saša Frank; Gunther Marsche; Sebastian E. Illanes; Christian Wadsack
Source:
Biochimica et biophysica acta 2020 v.1865 no.4 pp. 158632
ISSN:
1388-1981
Subject:
adults; arteries; blood; calcium; cell proliferation; endothelial cells; endothelium; high density lipoprotein; homeostasis; metabolism; microfilaments; mitogen-activated protein kinase; phospholipase C; pregnancy; progeny; receptors; vasodilation
Abstract:
... Perinatal and long-term offspring morbidities are strongly dependent on the preservation of placental vascular homeostasis during pregnancy. In adults, the HDL-apoM-S1P complex protects the endothelium and maintains vascular integrity. However, the metabolism and biology of cord blood-derived HDLs (referred to as neonatal HDL, nHDL) strikingly differ from those in adults. Here, we investigate the ...
DOI:
10.1016/j.bbalip.2020.158632

19. Effects of radiative heat and magnetic field on blood flow in an inclined tapered stenosed porous artery

Author:
J. U. Abubakar; A. D. Adeoye
Source:
Journal of Taibah University for Science 2020 v.14 no.1 pp. 77-86
ISSN:
1658-3655
Subject:
arteries; blood flow; computer software; differential equation; magnetic fields; momentum; radiative transfer; spinal stenosis; temperature; vasoconstriction; velocity
Abstract:
... A porous tapered inclined stenosed artery under the influence of magnetic field with radiation was considered. The momentum and energy equations with thin radiation governing the blood flow in the inclined artery were obtained taking the flow to be Newtonian. These equations were simplified under assumptions of mild stenosis, non-dimensionalized and solved using Differential Transform Method (DTM) ...
DOI:
10.1080/16583655.2019.1701397

20. Epigenetic control of atherosclerosis via DNA methylation: A new therapeutic target?

Author:
Armita Mahdavi Gorabi; Peter E. Penson; Maciej Banach; Morteza Motallebnezhad; Tannaz Jamialahmadi; Amirhossein Sahebkar
Source:
Life sciences 2020 v.253 pp. 117682
ISSN:
0024-3205
Subject:
DNA methylation; arteries; atherosclerosis; endothelial cells; epigenetics; foam cells; genes; histone code; inflammation; microRNA; myocytes; oxidative stress; physiology; smooth muscle; therapeutics
Abstract:
... Atherosclerosis is a disease in which lipid-laden plaques are developed inside the vessel walls of arteries. The immune system is activated, resulting in inflammation and oxidative stress. Endothelial cells (ECs) are activated, arterial smooth muscle cells (SMCs) proliferate, macrophages are activated, and foam cells are developed, leading to dysfunctional ECs. Epigenetic regulatory mechanisms, in ...
DOI:
10.1016/j.lfs.2020.117682

21. Evaluation of the effects of medial saphenous venous pressures as an indirect method of measurement of intra‐abdominal pressures in the horse

Author:
Amelia S. Munsterman; Alexandra M. Gillen; Matthew O. D. Coleridge; R. Reid Hanson
Source:
Journal of veterinary emergency and critical care 2020 v.30 no.6 pp. 660-669
ISSN:
1479-3261
Subject:
abdomen; arteries; artificial pneumoperitoneum; carbon dioxide; geldings; heart rate; horse breeds; hypertension; in vivo studies; laparoscopy; mares; mixed breeds; respiratory rate; saphenous vein
Abstract:
... OBJECTIVE: To evaluate the effect of changes in intra‐abdominal pressure (IAP) on medial saphenous venous pressure (MSVP) and hemodynamics in normal horses. DESIGN: Experimental, in‐vivo study. SETTING: University Teaching Hospital. ANIMALS: Convenience sample of 7 mixed breed horses; 5 geldings, and 2 mares. INTERVENTIONS: Pneumoperitoneum was induced in horses under standing sedation with carbon ...
DOI:
10.1111/vec.13000

22. Evidence of a limb- and shear stress stimulus profile-dependent impact of high-intensity cycling training on flow-mediated dilation

Author:
Trevor J. King; Kyra E. Pyke
Source:
Applied physiology, nutrition and metabolism 2020 v.45 no.2 pp. 135-145
ISSN:
1715-5320
Subject:
arteries; exercise; heart rate; hyperemia; males; shear stress; ultrasonics
Abstract:
... Lower limb endurance training can improve conduit artery flow-mediated dilation (FMD) in response to transient increases in shear stress (reactive hyperemia; RH-FMD) in both the upper and lower limbs. Sustained increases in shear stress recruit a partially distinct transduction pathway and elicit a physiologically relevant FMD response (SS-FMD) that provides distinct information regarding endothel ...
DOI:
10.1139/apnm-2019-0151

23. Fabrication of radiopaque drug-eluting beads based on Lipiodol/biodegradable-polymer for image-guided transarterial chemoembolization of unresectable hepatocellular carcinoma

Author:
Yutaka Okamoto; Terumitsu Hasebe; Kenta Bito; Kosaku Yano; Tomohiro Matsumoto; Kosuke Tomita; Atsushi Hotta
Source:
Polymer degradation and stability 2020 v.175 pp. 109106
ISSN:
0141-3910
Subject:
antineoplastic agents; arteries; biodegradability; hepatoma; image analysis; lactones; lipophilicity; microparticles; molecular weight; rabbits; therapeutics; weight loss
Abstract:
... New radiopaque/biodegradable drug-eluting beads (DEBs) for transarterial chemoembolization (TACE) were fabricated using Lipiodol and polycaprolactone (PCL) (Lipiodol/PCL beads) through a microfluidic device. TACE is the most extensively-applied therapy for unresectable hepatocellular carcinoma (HCC). DEBs are embolic microspheres with sustained and tumor-selective drug-delivery characteristics for ...
DOI:
10.1016/j.polymdegradstab.2020.109106

24. Feeding artery aneurysms associated with large meningiomas: case report and review of the literature

Author:
Kyriakos Papadimitriou; Alda Rocca; Vincent Dunet; Roy Thomas Daniel
Source:
Heliyon 2020 v.6 no.5 pp. e04071
ISSN:
2405-8440
Subject:
aneurysm; arteries; brain neoplasms; case studies; patients; surgery; wills
Abstract:
... Though brain tumors and intracranial aneurysms co-exist, the occurrence of feeding artery aneurysms with meningiomas are unusual. We describe here a large falcine meningioma that was associated with three feeding artery aneurysms of the anterior circulation. These aneurysms can be treated either by pre-operative endovascular therapy or during the meningioma surgery. The management strategy for the ...
DOI:
10.1016/j.heliyon.2020.e04071

25. Fetal and postnatal zinc restriction: sex differences in the renal renin-angiotensin system of newborn and adult Wistar rats

Author:
María Natalia Gobetto; Facundo Mendes Garrido Abregú; Carolina Caniffi; Luciana Veiras; Rosana Elesgaray; Mariela Gironacci; Analía Lorena Tomat; Cristina Arranz
Source:
Journal of nutritional biochemistry 2020 v.81 pp. 108385
ISSN:
0955-2863
Subject:
adults; angiotensin II; apoptosis; arteries; cardiovascular diseases; diet; females; gender differences; gene expression; glomerular filtration rate; lactation; males; messenger RNA; neonates; nutrient deficiencies; peptidyl-dipeptidase A; postnatal development; pregnancy; progeny; protein synthesis; rats; receptors; renin-angiotensin system; systolic blood pressure; weaning; zinc
Abstract:
... This study aimed to evaluate renal morphology and the renal renin-angiotensin system in 6- and 81-day-old male and female offspring exposed to zinc deficiency during fetal life, lactation and/or postnatal growth. Female Wistar rats were fed low- or control zinc diets from pregnancy to offspring weaning. Afterwards, offspring were fed a low- or a control zinc diet until 81 days of life. In 6- and/o ...
DOI:
10.1016/j.jnutbio.2020.108385

26. Functional effects of urotensin-II on intracellular pH regulators in human radial artery smooth muscle cells

Author:
Shih-Hurng Loh; Chung-Yi Chang; Shu-Fu Huang; Shih-Chi Chao; Wei-Kuo Lin; Eagle Yi-Kung Huang; Chien-Sung Tsai; Yi-Ting Tsai
Source:
Peptides 2020 v.126 pp. 170236
ISSN:
0196-9781
Subject:
acidification; alkalinization; ammonium chloride; arteries; cardiovascular diseases; extruders; extrusion; fluorescent dyes; humans; myocytes; pH; patients; smooth muscle; transporters; vasoconstrictor agents
Abstract:
... The regulation of intracellular pH (pHᵢ) plays a vital role in various cellular functions. We previously demonstrated that three different acid extruders, the Na⁺-H⁺ exchanger (NHE), Na⁺−HCO₃⁻ co-transporter (NBC) and H⁺-linked monocarboxylate transporter (MCT), functioned together in cultured human radial artery smooth muscle cells (HRASMCs). However, the functions of acid-loading transporters in ...
DOI:
10.1016/j.peptides.2019.170236

27. Generation of rat blood vasculature and hematopoietic cells in rat-mouse chimeras by blastocyst complementation

Author:
Xiaomin Wang; Hui Shi; Juanjuan Zhou; Qingjian Zou; Quanjun Zhang; Shixue Gou; Pengfei Chen; Lisha Mou; Nana Fan; Yangyang Suo; Zhen Ouyang; Chengdan Lai; Quanmei Yan; Liangxue Lai
Source:
Journal of genetics and genomics 2020 v.47 no.5 pp. 249-261
ISSN:
1673-8527
Subject:
B-lymphocytes; T-lymphocytes; arteries; blastocyst; chimerism; embryonic mortality; embryonic stem cells; endothelial cells; graft rejection; hematopoietic stem cells; humans; major histocompatibility complex; mice; rats; vascular endothelial growth factor receptor-2; yolk sac
Abstract:
... Interspecies chimera through blastocyst complementation could be an alternative approach to create human organs in animals by using human pluripotent stem cells. A mismatch of the major histocompatibility complex of vascular endothelial cells between the human and host animal will cause graft rejection in the transplanted organs. Therefore, to achieve a transplantable organ in animals without reje ...
DOI:
10.1016/j.jgg.2020.05.002

28. Hemodynamic changes evaluated by Doppler ultrasonographic technology in the ovaries and uterus of dairy cattle after the puerperium

Author:
Elshymaa Ahmed Abdelnaby
Source:
Reproductive Biology 2020 v.20 no.2 pp. 202-209
ISSN:
1642-431X
Subject:
arteries; blood flow; calving; color; corpus luteum; dairy cows; estradiol; horns; ovulation; postpartum period; progesterone; ultrasonography; uterus
Abstract:
... The present detailed study aimed to establish for the first time the ovarian and uterine hemodynamic change in dairy cows after the end of the puerperal period to investigate a possible association between Doppler indices and volume of blood flow. Twenty cows weighing 500–600 kg (mean 400 ± 50 kg) and 4–5 years of age (mean 3.2 ± 0.5 years) categorized into two main groups (true anestrum, with cor ...
DOI:
10.1016/j.repbio.2020.03.001

29. Important anatomical variations of the superior posterior alveolar artery: Studied by cone beam computed tomography

Author:
Lucas Silva Padovani; Alcione Maria Soares Dutra Oliveira; Bernardo Carvalho Dutra; Fernando Oliveira Costa; Peterson Antônio Dutra Oliveira
Source:
Anatomia, histologia, embryologia 2020 v.49 no.6 pp. 798-804
ISSN:
0340-2096
Subject:
arteries; dental prosthesis; females; floors; hemorrhage; males; objectives; sinuses; surgery; tomography
Abstract:
... The knowledge of anatomical variations of the posterior superior alveolar artery (PSAA) is very important in surgeries for maxillary sinus (MS) elevation and subsequent insertion of dental implants, avoiding common and serious surgical complications. The main objective of this study was to analyse important anatomical variations of the PSAA by means of cone beam computed tomography (CBCT) examinat ...
DOI:
10.1111/ahe.12584

30. Mapping deposition of particles in reconstructed models of human arteries

Author:
Maria Khoury; Mark Epshtein; Hikaia Zidan; Hila Zukerman; Netanel Korin
Source:
Journal of controlled release 2020 v.318 pp. 78-85
ISSN:
0168-3659
Subject:
adhesion; animal models; arteries; blood cells; blood flow; geometry; humans; inflammation; microfluidic technology; nanocarriers
Abstract:
... Targeted drug delivery to diseased vasculature, such as atherosclerotic lesions, is a multistep process, which is based on the transport of drug carriers to a selected region and their deposition at the desired destination. Current modeling approaches, including microfluidics and animal models, fail to accurately simulate this multi-scale process in human arteries, where blood flow is dominant. He ...
DOI:
10.1016/j.jconrel.2019.12.004

31. Mapping the Fine-Scale Organization and Plasticity of the Brain Vasculature

Author:
Christoph Kirst; Sophie Skriabine; Alba Vieites-Prado; Thomas Topilko; Paul Bertin; Gaspard Gerschenfeld; Florine Verny; Piotr Topilko; Nicolas Michalski; Marc Tessier-Lavigne; Nicolas Renier
Source:
Cell 2020 v.180 no.4 pp. 780-795.e25
ISSN:
0092-8674
Subject:
adults; animal models; arteries; brain; data collection; deafness; disease models; graphs; image analysis; mice; microscopy; plasticity; stroke
Abstract:
... The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying variations of the vascular organization across individuals, brain regions, or disease models is challenging. We used immunolabeling and tissue clearing to image the vascular network of adult mouse brains and developed a pipeline to segment terabyte-sized multichannel images from light sheet microscopy, ena ...
DOI:
10.1016/j.cell.2020.01.028

32. Mapping the fine-scale spatial pattern of artificial light pollution at night in urban environments from the perspective of bird habitats

Author:
Xingyu Xue; Yi Lin; Qiming Zheng; Ke Wang; Jing Zhang; Jinsong Deng; Ghali Abdullahi Abubakar; Muye Gan
Source:
Science of the total environment 2020 v.702 pp. 134725
ISSN:
0048-9697
Subject:
arteries; birds; computer software; green infrastructure; habitats; land cover; lighting; planning; pollution; probability; remote sensing; urban areas; urban parks; woodlands
Abstract:
... The increase in artificial light at night (ALAN) is a global concern, while the pattern of ALAN pollution inside urban areas has not yet been fully explored. To fill this gap, we developed a novel method to map fine-scale ALAN pollution patterns in urban bird habitats using high spatial resolution ALAN satellite data. First, an ALAN pollution map was derived from JL1-3B satellite images. Then, the ...
DOI:
10.1016/j.scitotenv.2019.134725

33. Mature Twin Neonates Exhibit Oxidative Stress via Nitric Oxide Synthase Dysfunctionality: A Prognostic Stress Marker in the Red Blood Cells and Umbilical Cord Vessels

Author:
Payal Chakraborty; Krisztina N. Dugmonits; Hajnalka Orvos; Edit Hermesz
Source:
Antioxidants 2020 v.9 no.9 pp. -
ISSN:
2076-3921
Subject:
Ursidae; anaerobic conditions; antioxidants; arteries; cardiovascular diseases; endothelial nitric oxide synthase; endothelium; erythrocytes; fetus; innervation; low birth weight; neonates; oxidative stress; pregnancy; premature birth; twins; umbilical cord
Abstract:
... Intrauterine hypoxic condition increases the generation of reactive oxygen species and fetal oxidative stress. Multiple pregnancy always bears an additional oxidative stress condition with severe complications, such as prematurity, structural abnormalities, delayed development and low birthweight. The umbilical cord (UC) vessels, along with circulating fetal red blood cells (RBCs), highly determin ...
DOI:
10.3390/antiox9090845

34. Myeloid GRK2 Regulates Obesity-Induced Endothelial Dysfunction by Modulating Inflammatory Responses in Perivascular Adipose Tissue

Author:
María González-Amor; Rocío Vila-Bedmar; Raquel Rodrigues-Díez; Rosa Moreno-Carriles; Alba C. Arcones; Marta Cruces-Sande; Mercedes Salaices; Federico Mayor; Ana M. Briones; Cristina Murga
Source:
Antioxidants 2020 v.9 no.10 pp. -
ISSN:
2076-3921
Subject:
G-protein coupled receptors; NAD(P)H oxidase (H2O2-forming); T-lymphocytes; acetylcholine; adipose tissue; aneurysm; antioxidants; arteries; high fat diet; inflammation; insulin; leptin; macrophages; mice; necrosis; neoplasms; obesity; patients; therapeutics; vasodilation
Abstract:
... Perivascular adipose tissue (PVAT) is increasingly being regarded as an important endocrine organ that directly impacts vessel function, structure, and contractility in obesity-associated diseases. We uncover here a role for myeloid G protein-coupled receptor kinase 2 (GRK2) in the modulation of PVAT-dependent vasodilation responses. GRK2 expression positively correlates with myeloid- (CD68) and l ...
DOI:
10.3390/antiox9100953

35. Ochratoxin A triggered intracerebral hemorrhage in embryonic zebrafish: Involvement of microRNA-731 and prolactin receptor

Author:
Ting-Shuan Wu; Yu-Ting Lin; Ying-Tzu Huang; Feng-Yih Yu; Biing-Hui Liu
Source:
Chemosphere 2020 v.242 pp. 125143
ISSN:
0045-6535
Subject:
Danio rerio; arteries; brain; dose response; edema; embryo (animal); erythrocytes; hemorrhage; histology; ochratoxin A; prolactin receptors
Abstract:
... Ochratoxin A (OTA), a mycotoxin widely found in foodstuffs, reportedly damages multiple brain regions in developing rodents, but the corresponding mechanisms have not been elucidated. In this study, zebrafish embryos at 6 h post fertilization (hpf) were exposed to various concentrations of OTA and the phenomenon associated with intracerebral hemorrhage was observed at 72 hpf. Exposure of embryos t ...
DOI:
10.1016/j.chemosphere.2019.125143

36. Optimal diet and lifestyle strategies for the management of cardio-metabolic risk

Author:
Bruce A. Griffin
Source:
Proceedings of the Nutrition Society 2020 v.79 no.1 pp. 1-3
ISSN:
1475-2719
Subject:
abdominal cavity; adipose tissue; arteries; brain; diet; eating habits; heart; insulin resistance; issues and policy; lifestyle; liver; medicine; nutrition risk assessment; optimal nutrition; overweight; pancreas; skeletal muscle; United Kingdom
Abstract:
... Cardio-metabolic risk (CMR) embodies a clustering of metabolic abnormalities that increase the likelihood of developing CVD in the large arteries of the heart, peripheral tissues and brain. These abnormalities share a common origin of insulin resistance, which manifests typically as excess visceral adipose tissue in the abdominal cavity, and within cells of key metabolic tissues (ectopic fat), inc ...
DOI:
10.1017/S0029665119001149

37. Periprocedural vascular access complications associated with percutaneous femoral arterial access using the modified Seldinger's technique in dogs during cardiac catheterization: a single-center experience

Author:
D.J. Stern; T. Gunasekaran; R.A. Sanders
Source:
Journal of veterinary cardiology 2020 v.32 pp. 28-32
ISSN:
1760-2734
Subject:
arteries; blood transfusion; catheters; contusions; dogs; hematoma; hemostasis; postoperative complications; surgery
Abstract:
... The primary objective of this study is to evaluate the peri-procedural major and minor complications associated with percutaneous femoral arterial access using modified Seldinger’s technique in dogs that underwent cardiac catheterization.Medical records of 62 client owned dogs that underwent percutaneous femoral arterial access for interventional cardiac procedures were retrospectively evaluated. ...
DOI:
10.1016/j.jvc.2020.09.004

38. Pro-angiogenic activity of Tongnao decoction on HUVECs in vitro and zebrafish in vivo

Author:
Jianli Wang; Xiao-Huan Zhang; Xiaoyu Xu; Qing Zhu; Beibei Yao; Seng Liang; Zhaoyao Chen; Yuxuan Wang; Ming-Fang He; Minghua Wu
Source:
Journal of ethnopharmacology 2020 v.254 pp. 112737
ISSN:
0378-8741
Subject:
Danio rerio; angiogenesis; arteries; cell viability; dose response; embryo (animal); genetically modified organisms; hospitals; human umbilical vein endothelial cells; ischemia; mitogen-activated protein kinase; non-specific serine/threonine protein kinase; phosphatidylinositol 3-kinase; stroke; therapeutics; tissue repair; traditional medicine; vascular endothelial growth factor receptor-2; China
Abstract:
... Tongnao Decoction (TND) is a Chinese decoction approved and used in Jiangsu Province Hospital for the treatment of ischemic stroke. It shows conclusive efficiency in the improvement of neurologic impairment and activities of daily living of the patients.Recently, angiogenesis has been recognized as a potential therapeutic strategy for treating cerebral ischemia. This study was aimed to provide com ...
DOI:
10.1016/j.jep.2020.112737

39. Prostanoids contribute to regulation of inwardly rectifying K+ channels in intrarenal arterial smooth muscle cells

Author:
Yu Liu; Ye Wang; Pengmei Guo; Qiying Song; Miaomaio Dong; Xiaomin Hou; Mingsheng Zhang
Source:
Life sciences 2020 v.250 pp. 117586
ISSN:
0024-3205
Subject:
agonists; antagonism; arteries; blood circulation; calcium; enzyme inhibition; fluorescent dyes; myocytes; nitric oxide; potassium; potassium channels; prostaglandin synthase; prostaglandins; rats; smooth muscle; sodium; vasoconstrictor agents
Abstract:
... The inward rectifier K⁺ (Kir) channels and prostanoids are important factors in regulating vascular tone, but the relationship between them has not been well studied. We aimed to study the involvement of prostanoids in regulating Kir activity in the rat intrarenal arteries (RIRAs).The vascular tone of isolated RIRAs was recorded with a wire myograph. The intracellular Ca²⁺ concentrations ([Ca²⁺]ᵢ) ...
DOI:
10.1016/j.lfs.2020.117586

40. Protective effects and potential mechanism of salvianolic acid B on sodium laurate-induced thromboangiitis obliterans in rats

Author:
Ziru Zhang; Jianbo Ji; Dawei Zhang; Maoqiang Ma; Longru Sun
Source:
Phytomedicine 2020 v.66 pp. 153110
ISSN:
0944-7113
Subject:
Oriental traditional medicine; Salvia miltiorrhiza; arteries; drugs; endothelins; enzyme-linked immunosorbent assay; eosin; humans; immunohistochemistry; inducible nitric oxide synthase; inflammation; intravenous injection; protective effect; rats; roots; salvianolic acid; staining; tail; thrombosis; thromboxanes; tumor necrosis factor-alpha
Abstract:
... The root of Salvia miltiorrhiza f. alba (RSMA) (Lamiaceae) is used for the treatment of patients with thromboangiitis obliterans (TAO) in traditional Chinese medicine. Previously, a mixture of phenolic acids extracted from RSMA has shown significant protective effects on TAO rats.This study investigates the inhibitory effects of salvianolic acid B on TAO induced by sodium laurate injection in rats ...
DOI:
10.1016/j.phymed.2019.153110

41. Quantitative bidimentional and Doppler ultrasound assessment of the effect of a GnRH antagonist on canine prostatic hyperplasia

Author:
F. D’Francisco; M. Lopez Merlo; C. Lapuente; A. Blasco; C. Gobello
Source:
Theriogenology 2020 v.144 pp. 41-44
ISSN:
0093-691X
Subject:
antagonists; arteries; blood flow; dogs; gonadotropin-releasing hormone; hyperplasia; prostate gland; therapeutics; ultrasonography
Abstract:
... The objectives of this article were: a) To describe the effect of a single administration of the third generation GnRH antagonist, acyline, on canine benign prostatic hyperplasia (BPH) b)To quantitatively compare parenchyma echogenicity, heterogeneity (SD echogenicity) and blood flow in hyperplastic and treated prostate glands. Seven mixed bred dogs, 11.14 ± 0.8 years of age, weighing 8.5 ± 1.4 (3 ...
DOI:
10.1016/j.theriogenology.2019.12.018

42. Regulation of Vascular Calcification by Reactive Oxygen Species

Author:
Andrea Tóth; Enikő Balogh; Viktória Jeney
Source:
Antioxidants 2020 v.9 no.10 pp. -
ISSN:
2076-3921
Subject:
arteries; atherosclerosis; calcification; crystals; diabetes; hydroxyapatite; kidney diseases; models; myocytes; phenotype; reactive oxygen species; signal transduction; smooth muscle; therapeutics
Abstract:
... Vascular calcification is the deposition of hydroxyapatite crystals in the medial or intimal layers of arteries that is usually associated with other pathological conditions including but not limited to chronic kidney disease, atherosclerosis and diabetes. Calcification is an active, cell-regulated process involving the phenotype transition of vascular smooth muscle cells (VSMCs) from contractile ...
DOI:
10.3390/antiox9100963

43. Relationship between angioarchitecture of the testicular artery and spermiogram parameters in Egyptian buffalo bulls (bubalus bubalis)

Author:
Ramadan G. Sary; Ragab H. Mohamed; Karim M. Khalil; Al‐Lethie A. Al‐lethie; Hassan A. Hussein
Source:
Reproduction in domestic animals 2020 v.55 no.3 pp. 343-350
ISSN:
0936-6768
Subject:
Bubalus bubalis; adults; arteries; blood flow; buffaloes; bulls; cell viability; droplets; epididymis; semen; slaughter; sperm motility; spermatozoa; testes
Abstract:
... The current study aimed to investigate the effect of testicular artery angioarchitecture on the spermiogram parameters in Egyptian Buffalo bulls. Eight adult buffalo bulls aged between 2 and 8 years were used for semen evaluation. For anatomical studies, the masculine gonads were collected after slaughtering 30 adult bulls and prepared for injection by different masses (Urographine®, Latex and Epo ...
DOI:
10.1111/rda.13635

44. Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose

Author:
Jing Zhou; Long Zhang; Bin Zheng; LiHui Zhang; Yan Qin; XinHua Zhang; Zhan Yang; ZiYuan Nie; GaoShan Yang; Jing Yu; JinKun Wen
Source:
Journal of ethnopharmacology 2020 v.262 pp. 113208
ISSN:
0378-8741
Subject:
Food and Drug Administration; Oriental traditional medicine; Salvia miltiorrhiza; Western blotting; animal disease models; antioxidant activity; arteries; atherosclerosis; bioluminescence assay; diabetes; gain-of-function mutation; gene expression regulation; gene overexpression; genes; glucose; heart failure; heme oxygenase (biliverdin-producing); hypertension; medicinal plants; messenger RNA; mice; myocytes; patients; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; smooth muscle; staining; transcription (genetics); China
Abstract:
... Traditional Chinese medicinal herb Salvia miltiorrhiza Bunge(Danshen) and its components have been widely used to treat cardiovascular diseases for hundreds of years in China, including hypertension, diabetes, atherosclerosis, and chronic heart failure. Salvia miltiorrhiza injection (SMI), an aqueous extracts of Salvia miltiorrhiza Bunge, is one of most widely used traditional Chinese medicine inj ...
DOI:
10.1016/j.jep.2020.113208

45. Self-propelled cellulose nanocrystal based catalytic nanomotors for targeted hyperthermia and pollutant remediation applications

Author:
Prodyut Dhar; Soundararajan Narendren; Surendra Singh Gaur; Saksham Sharma; Amit Kumar; Vimal Katiyar
Source:
International journal of biological macromolecules 2020 v.158 pp. 1020-1036
ISSN:
0141-8130
Subject:
arteries; biomass; catalytic activity; cellulose; chemotaxis; ferric oxide; fever; heat; lignocellulose; magnetic fields; nanocatalysts; nanocrystals; nanoparticles; pH; pollutants; remediation; surfactants
Abstract:
... Inspired from biological motors, cellulose nanocrystals (CNCs) are strategically modified to induce self-propulsion behavior with the capabilities to catalytically degrade pollutants along with magnetic hyperthermia to clean arterial plaques during its course of propulsion. CNCs derived from renewable biomass, are decorated with catalytically active, magneto-responsive nanomaterials (Fe₂O₃/Pd nano ...
DOI:
10.1016/j.ijbiomac.2020.04.204

46. Sex difference in cerebral blood flow velocity during exercise hyperthermia

Author:
Eric Rivas; Kyleigh N. Allie; Paolo M. Salvador; Lauren Schoech; Mauricio Martinez
Source:
Journal of thermal biology 2020 v.94 pp. 102741
ISSN:
0306-4565
Subject:
arteries; blood flow; blood pressure; carbon dioxide; cerebrum; exercise; fever; gender differences; heat production; heat stress; men; pain; thermoregulation; women
Abstract:
... Cerebral blood flow and thermal perception during physical exercise under hyperthermia conditions in females are poorly understood. Because sex differences exist for blood pressure control, resting middle cerebral artery velocity (MCAVₘₑₐₙ), and pain, we tested the hypothesis that females would have greater reductions in MCAvₘₑₐₙ and increased thermal perceptual strain during exercise hyperthermia ...
DOI:
10.1016/j.jtherbio.2020.102741

47. Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Author:
Joanna Kalucka; Laura P.M.H. de Rooij; Jermaine Goveia; Katerina Rohlenova; Sébastien J. Dumas; Elda Meta; Nadine V. Conchinha; Federico Taverna; Laure-Anne Teuwen; Koen Veys; Melissa García-Caballero; Shawez Khan; Vincent Geldhof; Liliana Sokol; Rongyuan Chen; Lucas Treps; Mila Borri; Pauline de Zeeuw; Charlotte Dubois; Tobias K. Karakach; Kim D. Falkenberg; Magdalena Parys; Xiangke Yin; Stefan Vinckier; Yuxiang Du; Robert A. Fenton; Luc Schoonjans; Mieke Dewerchin; Guy Eelen; Bernard Thienpont; Lin Lin; Lars Bolund; Xuri Li; Yonglun Luo; Peter Carmeliet
Source:
Cell 2020 v.180 no.4 pp. 764-779.e20
ISSN:
0092-8674
Subject:
arteries; brain; colon; data collection; endothelial cells; genes; genetic markers; heart; liver; mice; skeletal muscle; small intestine; spleen; taxonomy; testes; transcriptome; transcriptomics
Abstract:
... The heterogeneity of endothelial cells (ECs) across tissues remains incompletely inventoried. We constructed an atlas of >32,000 single-EC transcriptomes from 11 mouse tissues and identified 78 EC subclusters, including Aqp7⁺ intestinal capillaries and angiogenic ECs in healthy tissues. ECs from brain/testis, liver/spleen, small intestine/colon, and skeletal muscle/heart pairwise expressed partial ...
DOI:
10.1016/j.cell.2020.01.015

48. Statins with different lipophilic indices exert distinct effects on skeletal, cardiac and vascular smooth muscle

Author:
Jordon C. Irwin; Andrew S. Fenning; Rebecca K. Vella
Source:
Life sciences 2020 v.242 pp. 117225
ISSN:
0024-3205
Subject:
action potentials; arteries; atrophy; females; genes; hypertrophy; lipophilicity; messenger RNA; mitochondria; muscles; norepinephrine; pleiotropy; pravastatin; skeletal muscle; smooth muscle
Abstract:
... Data concerning the influence of statin lipophilicity on the myotoxic and pleiotropic effects of statins is conflicting, and mechanistic head-to-head comparison studies evaluating this parameter are limited. In order to address the disparity, this mechanistic investigation aimed to assess the effects of two short-acting statins with different lipophilic indices on skeletal, cardiac and vascular sm ...
DOI:
10.1016/j.lfs.2019.117225

49. Synthesis and assessment of sodium alginate-modified silk fibroin microspheres as potential hepatic arterial embolization agent

Author:
Guobao Chen; Runan Wei; Xiang Huang; Fuping Wang; Zhongmin Chen
Source:
International journal of biological macromolecules 2020 v.155 pp. 1450-1459
ISSN:
0141-8130
Subject:
anticoagulants; arteries; biocompatibility; biodegradability; cancer therapy; crosslinking; cytotoxicity; doxorubicin; emulsifying; fibroblasts; fibroins; hepatoma; microparticles; pH; particle size; sodium; sodium alginate; temperature
Abstract:
... Transcatheter arterial chemoembolization (TACE) is well known as an effective treatment for hepatocellular carcinoma (HCC). In the present study, a novel embolic agent of sodium alginate (SA)-modified silk fibroin (SF) microspheres was successfully prepared by emulsifying cross-linking method. The SA-modified SF microspheres were evaluated for the ability of embolization by investigating the morph ...
DOI:
10.1016/j.ijbiomac.2019.11.122

50. The identification of neuronal control pathways supplying effector tissues in the stomach

Author:
John B. Furness; Madeleine Di Natale; Billie Hunne; Lalita Oparija-Rogenmozere; Sean M. Ward; Kent C. Sasse; Terry L. Powley; Martin J. Stebbing; Deborah Jaffey; Linda J. Fothergill
Source:
Cell and tissue research 2020 v.382 no.3 pp. 433-445
ISSN:
0302-766X
Subject:
arteries; brain stem; cells; digesta; digestive juices; duodenum; esophagus; food intake; ganglia; gastrins; humans; immunohistochemistry; ingestion; motor neurons; muscles; peristalsis; rats; research; somatostatin; stomach; swine; tissues; volume
Abstract:
... The stomach acts as a buffer between the ingestion of food and its processing in the small intestine. It signals to the brain to modulate food intake and it in turn regulates the passage of a nutrient-rich fluid, containing partly digested food, into the duodenum. These processes need to be finely controlled, for example to restrict reflux into the esophagus and to transfer digesta to the duodenum ...
DOI:
10.1007/s00441-020-03294-7