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- Ganoza, Christian A., et al. Show all 6 Authors
- Vaccine 2013 v.31 no.9 pp. 1340-1348
- B-lymphocytes; BCG vaccine; Mycobacterium bovis BCG; T-lymphocytes; antibodies; bacterial antigens; blood serum; cell-mediated immunity; flow cytometry; immune response; interferon-gamma; randomized clinical trials; tuberculosis; vaccination; volunteers
- ... Current vaccination using Mycobacterium bovis bacillus Calmette-Guérin (BCG), fails to prevent pulmonary tuberculosis (TB). New vaccination strategies are essential for reducing the global incidence of TB. We assessed the safety and immunogenicity of VPM1002, a recombinant BCG vaccine candidate. EudraCT (2007-002789-37) and ClinicalTrials.gov (NCT00749034).Healthy volunteers were enrolled in a pha ...