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1. Efficient production of surfactin from xylose-rich corncob hydrolysate using genetically modified Bacillus subtilis 168

Author:
Hu, Fangxiang,   et al.   ; Liu, Yuyue; Lin, Junzhang; Wang, Weidong; Li, Shuang;     Show all 5 Authors
Source:
Applied microbiology and biotechnology 2020 v.104 no.9 pp. 4017-4026
ISSN:
0175-7598
Subject:
Bacillus subtilis; acyl coenzyme A; acyl-CoA dehydrogenase; biomass; biosurfactants; carbon; corn cobs; fermentation; gene overexpression; hydrolysates; ligases; monosodium glutamate; surfactin; transferases; wastewater; xylose
Abstract:
... As one of the most powerful biosurfactants, surfactin has extensive application prospects in numerous industrial fields. Bacillus subtilis 168 was genetically modified to produce surfactin by increasing the supply of the precursor fatty acyl-CoA by overexpressing 4′ phosphopantetheinyl transferase, medium-chain acyl-acyl carrier protein (ACP) thioesterase and fatty acyl CoA ligase (encoded by sfp, ...
DOI:
10.1007/s00253-020-10528-9