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- Author:
- Kehr, Nermin Seda, et al. ; Motealleh, Andisheh; De Marco, Rossella; Show all 3 Authors
- Source:
- Journal of materials chemistry B 2019 v.7 no.23 pp. 3716-3723
- ISSN:
- 2050-7518
- Subject:
- adverse effects; alginates; biopolymers; cell adhesion; coatings; drug delivery systems; drugs; electrostatic interactions; nanocomposites; neoplasm cells; neoplasms; pH
- Abstract:
- ... Drug delivery systems capable of providing controlled and localized drug release are a highly important tool in the biomedical field because they can provide site-specific, sustained, and controlled drug release at the place where the drug is most needed, and they allow for significantly lower doses of the drug at other parts of the body, reducing the drug's potential side effects. In this respect ...
- DOI:
- 10.1039/c9tb00591a
-
http://dx.doi.org/10.1039/c9tb00591a
- Author:
- Kehr, Nermin Seda, et al. ; Motealleh, Andisheh; Dorri, Pooya; Show all 3 Authors
- Source:
- Journal of materials chemistry B 2019 v.7 no.14 pp. 2362-2371
- ISSN:
- 2050-7518
- Subject:
- antineoplastic agents; biopolymers; cations; coatings; drug delivery systems; enantiomers; fibroblasts; models; optical isomerism; pH; porous media
- Abstract:
- ... We present the preparation of self-assembled monolayers (SAMs) of pH responsive chiral periodic mesoporous organosilicas (PMOs) as model implants with drug delivery ability. SAMs of pH responsive PMOs were prepared by layer-by-layer coating of PMOs with polyelectrolytes (e.g. the enantiomers of a polycation biopolymer), for delivering organic molecules and anticancer drug molecules locally in a co ...
- DOI:
- 10.1039/c8tb02507j
-
http://dx.doi.org/10.1039/c8tb02507j
- Author:
- Kehr, Nermin Seda, et al. ; Motealleh, Andisheh; Schäfer, Andreas H.; Show all 3 Authors
- Source:
- ACS Applied Materials & Interfaces 2016 v.8 no.51 pp. 35081-35090
- ISSN:
- 1944-8252
- Subject:
- biopolymers; cell adhesion; cell growth; crystals; extracellular matrix; fibroblasts; glass; nanoparticles; zeolites
- Abstract:
- ... Nanoparticle density gradients on surfaces have attracted interest as two-dimensional material surfaces that can mimic the complex nano-/microstructure of the native extracellular matrix, including its chemical and physical gradients, and can therefore be used to systematically study cell–material interactions. In this respect, we report the preparation of density gradients made of bifunctional ze ...
- DOI:
- 10.1021/acsami.6b13667
-
http://dx.doi.org/10.1021%2Facsami.6b13667