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- Tsuda, Yoshimi, et al. Show all 6 Authors
- Virology journal 2017 v.14 no.1 pp. 13
- genome; blood; body weight changes; adults; clones; amino acids; viruses; patients; pathogenesis; glycoproteins; females; sequence analysis; fur; serotypes; mice; pathogenicity; neutralizing antibodies; kidneys; Hantaan orthohantavirus; inoculum; intravenous injection; hemorrhage; viral proteins; animal models; RNA; fever
- ... BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) caused by hantavirus infection is characterized by fever, renal dysfunction and hemorrhage. An animal model mimicking symptoms of HFRS remains to be established. In this study, we evaluated the pathogenicity of an HFRS patient-derived Hantaan virus (HTNV) in adult mice. METHODS: Five clones of HTNV strain KHF 83-61 BL (KHFV) that was derived ...
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- Sakata, Yoshimi, et al. Show all 7 Authors
- Ticks and tick-borne diseases 2012 v.3 no.5-6 pp. 308-311
- Anaplasma bovis; DNA; Ehrlichia; Feline immunodeficiency virus; Rickettsia; blood; cats; nucleotide sequences; quantitative polymerase chain reaction; ribosomal RNA; screening; sequence analysis; surveys; tick-borne diseases; ticks; Japan
- ... The prevalence of Rickettsia, Ehrlichia, and Anaplasma in 1764 DNA samples extracted from feline peripheral blood from all 47 prefectures in Japan was evaluated by screening real-time PCR, genus-specific PCR, and DNA nucleotide sequencing. The survey revealed that all cats were negative for Rickettsia infection. Two cats were positive for Ehrlichia or Anaplasma based on the screening PCR assay. Nu ...