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You searched for: Subject term bone density Remove constraint Subject term: bone density Subject term bone strength Remove constraint Subject term: bone strength
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1. 3-Hydroxy-3-methylbutyrate administration diminishes fundectomy-induced osteopenia of the lumbar spine in pigs

Author:
Tatara, Marcin R.; Śliwa, Ewa; Krupski, Witold; Worzakowska, Marta
Source:
Nutrition 2008 v.24 no.7-8 pp. 753-760
ISSN:
0899-9007
Subject:
diet-related diseases; chemical concentration; human diseases; leucine; vertebrae; hydroxyapatite; osteopenia; surgery; bone density; animal models; human nutrition; bone mineralization; bone strength; metabolites; swine
Abstract:
... Objective: The aim of the study was to test the hypothesis that oral administration with 3-hydroxy-3-methylbutyrate (HMB) positively influences bone metabolism and diminishes fundectomy-induced osteopenia of the axial skeleton in pigs. The pig model was chosen because of its recognized physiologic and anatomic similarities of the gastrointestinal tract and skeletal system to those of humans. Metho ...
DOI:
10.1016/j.nut.2008.03.009
PubMed:
18490141

2. A High Mixed Protein Diet Reduces Body Fat without Altering the Mechanical Properties of Bone in Female Rats

Author:
Pye, Kathleen M.; Wakefield, Andrew P.; Aukema, Harold M.; House, James D.; Ogborn, Malcolm R.; Weiler, Hope A.
Source:
Journal of nutrition 2009 v.139 no.11 pp. 2099-2105
ISSN:
0022-3166
Subject:
osteocalcin; microstructure; insulin-like growth factor I; females; dietary protein; bone metabolism; blood chemistry; adiponectin; body weight; calcium; leptin; high protein diet; collagen; bone density; animal models; rats; bone strength; body fat
Abstract:
... Long-term consumption of high-protein (HP) diets at 35% of energy is postulated to negatively influence bone health. Previous studies have not comprehensively examined the biochemical, physical, and biomechanical properties of bone required to arrive at this conclusion. Our objective in this study was to examine the long-term effect of a HP diet on bone metabolism, mass, and strength in rats. Adul ...
DOI:
10.3945/jn.109.106377
PubMed:
19759249

3. A comparison of the quality of whole corn tortillas made from instant corn flours by traditional or extrusion processing

Author:
Gomez-Aldapa, C.; Martinez-Bustos, F.; Figueroa, C.J.D.; Ordorica, F.C.A.
Source:
International journal of food science & technology 1999 v.34 no.4 pp. 391-399
ISSN:
0950-5423
Subject:
bone density; food composition; bone mineralization; phosphorus; raw foods; corn flour; nutrient uptake; mineral content; bone strength; protein composition; weight; food processing quality; tortillas; calcium; extrusion; nixtamalization; rats; extruded foods; nutritive value; magnesium; animal models; femur
Abstract:
... The nutritional quality (chemical and biological assays) was evaluated for tortillas made with two samples of instant corn flour prepared with 0.15 and 0.25% calcium hydroxide and processed either by extrusion or by the traditional process (nixtamalization). Both raw corn and the tortillas made from instant whole corn flours prepared by extrusion (TEP) had higher Protein Efficiency Ratio (PER), an ...
DOI:
10.1046/j.1365-2621.1999.00287.x

4. A dairy product fermented by lactobacilli cancels the adverse effects of hypochlorhydria induced by a proton pump inhibitor on bone metabolism in growing rats

Author:
Satoshi Takasugi; Kinya Ashida; Suyaka Maruyama; Yukari Komaba; Tetsuo Kaneko; Taketo Yamaji
Source:
British journal of nutrition 2011 v.106 no.10 pp. 1487-1494
ISSN:
1475-2662
Subject:
Lactobacillus; X-radiation; adverse effects; bone density; bone resorption; bone strength; calcium; collagen; dairy consumption; excretion; experimental diets; fermented dairy products; hyperparathyroidism; malabsorption; osteocalcin; parathyroid hormone; proton pump; rats; tomography
Abstract:
... The purpose of the present study is to investigate the effects of hypochlorhydria induced by proton pump inhibitor (PPI) administration and intake of a dairy product fermented by lactobacilli (DFL) on bone metabolism in growing rats. Male rats, aged 3 weeks, were divided into two groups: a control group fed a casein-based diet and a group fed a DFL-based diet. Each group was fed its respective exp ...
DOI:
10.1017/S0007114511002017
PubMed:
21736787

5. A dietary pattern rich in calcium, potassium, and protein is associated with tibia bone mineral content and strength in young adults entering initial military training

Author:
Anna T Nakayama; Laura J Lutz; Adela Hruby; James P Karl; James P McClung; Erin Gaffney-Stomberg
Source:
American journal of clinical nutrition 2019 v.109 no.1 pp. 186-196
ISSN:
1938-3207
Subject:
body mass index; bone density; bone strength; calcium; computed tomography; cross-sectional studies; eating habits; education; energy; etiology; exercise; food frequency questionnaires; food intake; men; mineral content; potassium; randomized clinical trials; regression analysis; stress fractures; tibia; women; young adults
Abstract:
... Stress fracture risk is elevated during initial military training (IMT), particularly in lower-extremity bones such as the tibia. Although the etiology of stress fractures is multifactorial, lower bone strength increases risk. The objective of this study was to assess, through the use of peripheral quantitative computed tomography, whether adherence to a dietary pattern rich in calcium, potassium, ...
DOI:
10.1093/ajcn/nqy199

6. A mild magnesium deprivation affects calcium excretion but not bone strength and shape, including changes induced by nickel deprivation, in the rat

Author:
Forrest H. Nielsen
Source:
Biological trace element research 2006 v.110 no.2 pp. 133-149
ISSN:
0163-4984
Subject:
magnesium; nutrient deficiencies; calcium; excretion; urine; bone density; bone formation; bone strength; mineral content; mineral metabolism; nickel; rats
Abstract:
... An experiment was performed to determine the effect of a mild magnesium deprivation on calcium metabolism and bone composition, shape, and strength in rats, and whether nickel deprivation exacerbated or alleviated any changes caused by the magnesium deprivation. Weanling male rats were assigned to groups of 10 in a factorial arrangement, with variables being supplemental nickel at 0 and 1 mg/kg an ...
Handle:
10113/35393
DOI:
10.1385/BTER:110:2:133
PubMed:
16757842

7. A soluble activin type IIA receptor induces bone formation and improves skeletal integrity

Author:
Pearsall, R. Scott; Canalis, Ernesto; Cornwall-Brady, Milton; Underwood, Kathryn W.; Haigis, Brendan; Ucran, Jeffrey; Kumar, Ravindra; Pobre, Eileen; Grinberg, Asya; Werner, Eric D.; Glatt, Vaida; Stadmeyer, Lisa; Smith, Deanna; Seehra, Jasbir; Bouxsein, Mary L.
Source:
Proceedings of the National Academy of Sciences of the United States of America 2008 v.105 no.19 pp. 7082-7087
ISSN:
0027-8424
Subject:
bone density; bone formation; bone resorption; bone strength; mice; ovariectomy; risk; transforming growth factor beta
Abstract:
... Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the TGF-β superfamily have been shown to be involved in the regulation of bone mass. Activin A, a TGF-β signaling ligand, is present at high levels in bone and may play a role in the regulation of bone metabolism. Here we demonstrate that pharmacological blockade of ligand si ...
DOI:
10.1073/pnas.0711263105
PubMed:
18460605
PubMed Central:
PMC2383948

8. A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength

Author:
Marc Baud’huin; Nicolas Solban; Milton Cornwall-Brady; Dianne Sako; Yoshimi Kawamoto; Katia Liharska; Darren Lath; Mary L. Bouxsein; Kathryn W. Underwood; Jeffrey Ucran; Ravindra Kumar; Eileen Pobre; Asya Grinberg; Jasbir Seehra; Ernesto Canalis; R. Scott Pearsall; Peter I. Croucher
Source:
Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.30 pp. 12207-12212
ISSN:
0027-8424
Subject:
acid phosphatase; blood serum; bone density; bone formation; bone morphogenetic proteins; bone resorption; bone strength; homeostasis; mice; organogenesis; osteoblasts; osteoclasts; osteoporosis; transcription factor NF-kappa B; transforming growth factor beta
Abstract:
... Diseases such as osteoporosis are associated with reduced bone mass. Therapies to prevent bone loss exist, but there are few that stimulate bone formation and restore bone mass. Bone morphogenetic proteins (BMPs) are members of the TGFβ superfamily, which act as pleiotropic regulators of skeletal organogenesis and bone homeostasis. Ablation of the BMPR1A receptor in osteoblasts increases bone mass ...
DOI:
10.1073/pnas.1204929109
PubMed:
22761317
PubMed Central:
PMC3409793

9. A study on spontaneously obese rat (Minko rat) with abnormal lipid metabolism, strength and mineral concentrations in bone

Author:
Takeda, R.; Nakamura, T.; Imanishi, M.; Ishida, M.; Yano, F.; Takeda, T.; Kimura, M.
Source:
Journal of the American College of Nutrition 2004 v.23 no.6 pp. 712S-714S
ISSN:
0731-5724
Subject:
obesity; lipid metabolism; bone density; dietary minerals; calcium; magnesium; phosphorus; bone strength
Abstract:
... OBJECTIVES: In view of the prevalence of osteoporosis in Japan, which surveys have shown has almost doubled over the last ten years, contributory factors, additional to the mineral status, that affect bone stiffness have been explored in spontaneously obese (Minko) rats. METHODS: Bone stiffness and strength as well as content of Mg, Ca, P, Na, K, and trace minerals in femurs were compared in male ...
DOI:
10.1080/07315724.2004.10719414

10. A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development

Author:
Ward, Wendy E.; Kim, Susie; Bruce, W. Robert
Source:
British journal of nutrition 2003 v.90 no.3 pp. 589-595
ISSN:
0007-1145
Subject:
animal feeding; biomechanics; bone density; bone strength; calcium; cholecalciferol; diet; females; femur; folic acid; mineral content; nutrient content; rats; risk; weight gain
Abstract:
... Evidence from epidemiological and animal-feeding trials suggests that a western-style diet that is high in fat, and low in Ca, vitamin D and folic acid may result in low bone mass and poor bone quality: this leads to an increased risk of fragility fracture. The overall objective of the present study was to determine the effect of feeding a western-style diet (low in Ca (0·4 g/kg diet, Ca:P ratio 1 ...
DOI:
10.1079/BJN2003952
PubMed:
13129465

11. Accuracy and precision of dual-energy x-ray absorptiometry for ex vivo determination of mineral content in turkey poult bones

Author:
Zotti, Alessandro; Rizzi, Chiara; Chiericato, Gianmaria; Bernardini, Daniele
Source:
Veterinary radiology & ultrasound 2003 v.44 no.1 pp. 49-52
ISSN:
1058-8183
Subject:
ash content; bone density; bone strength; correlation; dual-energy X-ray absorptiometry; equations; humerus; linear models; mineral content; poults
Abstract:
... The right humerus was removed from 30 20-week-old male turkey poults for humerus strength analysis using dual-energy x-ray absorptiometry and humerus-breaking strength. Specimens were cleaned and dried before scanning. To determine the most precise and accurate protocol of bone densitometry analysis for avian long bones, we scanned each specimen using five different techniques, all aimed to simula ...
DOI:
10.1111/j.1740-8261.2003.tb01448.x
PubMed:
12620050

12. Achyranthes bidentata root extract prevent OVX-induced osteoporosis in rats

Author:
Rong Zhang; Shi-Jie Hu; Chen Li; Feng Zhang; Hong-Quan Gan; Qi-Bing Mei
Source:
Journal of ethnopharmacology 2012 v.139 no.1 pp. 12-18
ISSN:
0378-8741
Subject:
Achyranthes japonica; alkaline phosphatase; alternative medicine; biomarkers; bone density; bone resorption; bone strength; calcium; dual-energy X-ray absorptiometry; excretion; micro-computed tomography; oral administration; osteocalcin; osteoporosis; ovariectomy; phosphorus; rats; uterus; weight gain
Abstract:
... AIM: The objective of the present study was to systematically investigate the effects of Achyranthes bidentata root extract (ABRE) on postmenopausal osteoporosis. MATERIALS AND METHODS: Eighty 3-month-old female Sprague–Dawley rats were used and randomly assigned into sham-operated group (SHAM) and five ovariectomy (OVX) subgroups, i.e. OVX with vehicle (OVX); OVX with 17β-ethinylestradiol (E₂, 25 ...
DOI:
10.1016/j.jep.2011.05.034
PubMed:
21669273

13. An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens

Author:
Dirk-Jan De Koning; Nazaret Dominguez-Gasca; Robert H. Fleming; Andrew Gill; Dominic Kurian; Andrew Law; Heather A. McCormack; David Morrice; Estefania Sanchez-Rodriguez; Alejandro B. Rodriguez-Navarro; Rudolf Preisinger; Matthias Schmutz; Veronica Šmídová; Frances Turner; Peter W. Wilson; Rongyan Zhou; Ian C. Dunn
Source:
Genetics, selection, evolution 2020 v.52 no.1 pp. 13
ISSN:
1297-9686
Subject:
White Leghorn; bone density; bone health; bone metabolism; bone strength; collagen; crosslinking; cystathionine beta-synthase; enzyme activity; exhibitions; gene expression; genes; genetic factors; genetic variation; genotype; homocysteine; laying hens; loci; natural selection; osteoporosis; oviposition; population; quantitative trait loci; selective breeding; single nucleotide polymorphism; spectroscopy; tibia; transcriptome; translational medical research; volume
Abstract:
... BACKGROUND: Skeletal damage is a challenge for laying hens because the physiological adaptations required for egg laying make them susceptible to osteoporosis. Previously, we showed that genetic factors explain 40% of the variation in end of lay bone quality and we detected a quantitative trait locus (QTL) of large effect on chicken chromosome 1. The aim of this study was to combine data from the ...
DOI:
10.1186/s12711-020-00532-y

14. Anti-osteoporotic effects of mixed compositions of extracellular polymers isolated from Aureobasidium pullulans and Textoria morbifera in ovariectomized mice

Author:
Chang-Soo Cho; Hye-Seong Jeong; In-Young Kim; Go-Woon Jung; Bon-Hwa Ku; Dong-Chan Park; Seung-Bae Moon; Hyung-Rae Cho; Khawaja Muhammad Imran Bashir; Sae Kwang Ku; Jae-Suk Choi
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 295
ISSN:
1472-6882
Subject:
Aureobasidium pullulans; Dendropanax; active ingredients; alkaline phosphatase; alternative medicine; animal models; blood chemistry; bone density; bone resorption; bone strength; calcium; femur; functional foods; histology; humans; inorganic phosphorus; menopause; mice; mineral content; osteocalcin; osteoporosis; ovariectomy; polymers; tea; traditional medicine; trees; women
Abstract:
... BACKGROUND: Extracellular polymeric substances isolated from Aureobasidium pullulans (EAP), containing specifically 13% β-1,3/1,6-glucan, have shown various favorable bone-preserving effects. Textoria morbifera Nakai (TM) tree has been used as an ingredient in traditional medicine and tea for various pharmacological purposes. Thus, the present study was aimed to examine the synergistic anti-osteop ...
DOI:
10.1186/s12906-018-2362-y
PubMed:
30400922
PubMed Central:
PMC6220464

15. Antiosteoporotic activity of Davallia formosana

Author:
Yu-Jen Ko; Jin-Bin Wu; Hui-Ya Ho; Wen-Chuan Lin
Source:
Journal of ethnopharmacology 2012 v.139 no.2 pp. 558-565
ISSN:
0378-8741
Subject:
Davallia; alkaline phosphatase; body weight; bone density; bone metabolism; bone strength; calcium; in vitro studies; microcomputers; oral administration; osteoporosis; quality control; rats; tomography; traditional medicine
Abstract:
... ETHANOPHARMACOLOGICAL RELEVANCE: In Taiwanese folk medicine, Davallia formosana is used to treat bone diseases, including osteoporosis. AIM: This study evaluated the anti-osteoporotic effect of ethanolic extract derived from Davallia formosana (DFE). MATERIALS AND METHODS: In this in vitro study, we investigated the inhibitory action of DFE on RANKL-stimulated osteoclastogenesis. The in vivo effec ...
DOI:
10.1016/j.jep.2011.11.050
PubMed:
22155390

16. Antiosteoporotic effects of 3:1 (g/g) mixed formulation of exopolymers purified from Aureobasidium pullulans SM‐2001 and Dendropanax morbifera leaf extracts in ovariectomized rats

Author:
Chang‐Soo Cho; Hye‐Seong Jeong; In‐Young Kim; Go‐Woon Jung; Bon‐Hwa Ku; Dong‐Chan Park; Seung‐Bae Moon; Hyung‐Rae Cho; Sae Kwang Ku; Jae‐Suk Choi
Source:
Journal of food biochemistry 2018 v.42 no.5 pp. e12548
ISSN:
0145-8884
Subject:
Aureobasidium pullulans; Dendropanax morbifer; biochemistry; blood chemistry; body weight; bone density; bone strength; developmental orthopedic disease; dose response; femur; histology; ingredients; leaf extracts; menopause; oral administration; osteoporosis; ovariectomy; rats; resorption; risk; tibia; urine; vertebrae; weight gain; women
Abstract:
... The dose‐dependent antiosteoporotic potentials of the exopolymers from Aureobasidium pullulans (EAP): Dendropanax morbifera (DM) 3:1 (g/g) were observed in bilateral ovariectomized (OVX) rats. Twenty‐eight days after bilateral OVX surgery, 200 mg/kg EAP or DM, and 400, 200, and 100 mg/kg EAP : DM (3:1) were orally administered, once a day for 56 days. We measured changes in body weight and weight ...
DOI:
10.1111/jfbc.12548

17. Antioxidative peptide from milk exhibits antiosteopenic effects through inhibition of oxidative damage and bone-resorbing cytokines in ovariectomized rats

Author:
Sanusi Bello Mada; Srinu Reddi; Naveen Kumar; Rohit Kumar; Suman Kapila; Rajeev Kapila; Ritu Trivedi; Anirudha Karvande; Naseer Ahmad
Source:
Nutrition 2017 v.43-44 pp. 21-31
ISSN:
0899-9007
Subject:
animal models; antioxidant activity; antioxidants; atrophy; blood serum; body weight changes; bone density; bone resorption; bone strength; buffalo milk; calcium; catalase; cytokines; endometrium; enzyme activity; femur; glutathione; human diseases; malondialdehyde; milk; osteoporosis; ovariectomy; oxidative stress; phosphorus; postmenopause; protective effect; rats; superoxide dismutase; tibia; transforming growth factor beta; weight loss
Abstract:
... Oxidative stress has been implicated as a crucial pathogenic factor in the development of postmenopausal osteoporosis. Milk-derived antioxidative peptides are gaining much attention toward the development of prodrugs for alleviating several human diseases, including osteoporosis. The aim of the present study was to determine whether antioxidant peptides are good candidates for alleviating postmeno ...
DOI:
10.1016/j.nut.2017.06.010

18. Arachidonic acid exacerbates diet-induced obesity and reduces bone mineral content without impacting bone strength in growing male rats

Author:
Ivy L Mak; Paula Lavery; Sherry Agellon; Frank Rauch; Monzur Murshed; Hope A Weiler
Source:
Journal of nutritional biochemistry 2019 v.73 pp. 108226
ISSN:
0955-2863
Subject:
adipocytes; adiposity; analysis of variance; arachidonic acid; blood serum; bone density; bone resorption; bone strength; dual-energy X-ray absorptiometry; energy intake; erythrocytes; fatty acid composition; femur; gas chromatography; high fat diet; laboratory animals; leptin; long chain polyunsaturated fatty acids; males; metabolism; micro-computed tomography; mineral content; obesity; rats; visceral fat
Abstract:
... Long-chain polyunsaturated fatty acids modulate bone mass and adipocyte metabolism. Arachidonic acid (AA, C20:4 n-6) is elevated in obesity and postulated to stimulate bone resorption. This study aimed to determine the effect of AA on bone mass, quality, and adiposity in diet-induced obesity during growth. Male Sprague–Dawley rats (n=42, 4-week) were randomized into groups fed a control diet (CTRL ...
DOI:
10.1016/j.jnutbio.2019.108226

19. Assessing bone mineral density in vivo: digitized fluoroscopy and ultrasound

Author:
Fleming, R.H.; Korver, D.; McCormack, H.A.; Whitehead, C.C.
Source:
Poultry science 2004 v.83 no.2 pp. 207-214
ISSN:
0032-5791
Subject:
laying hens; osteoporosis; bone density; humerus; ulna; ultrasonography; radiography; digital images; battery cages; extensive farming; image analysis; tibia; bone strength; shear strength; bending strength; heritability; quantitative traits; genetic correlation; phenotypic correlation; body weight; cholecalciferol; 25-hydroxycholecalciferol; free range husbandry
Abstract:
... The genetic component of osteoporosis in caged laying hens is large, and a method for detecting hens susceptible to fracture could be useful in breeding programs. A radiographic absorptiometry film method was modified by video digitization from an image intensifier and computer analysis and termed digitized fluoroscopy (DF). Humeral and ulnar DF values were measured in 165 hens during lay. Relatio ...
DOI:
10.1093/ps/83.2.207
PubMed:
14979571

20. Assessing bone mineral density in vivo: dual energy x-ray absorptiometry

Author:
Hester, P.Y.; Schreiweis, M.A.; Orban, J.I.; Mazzuco, H.; Kopka, M.N.; Ledur, M.C.; Moody, D.E.
Source:
Poultry science 2004 v.83 no.2 pp. 215-221
ISSN:
0032-5791
Subject:
dual-energy X-ray absorptiometry; laying hens; broiler breeders; humerus; bone density; animal age; nondestructive methods; mineral content; bone strength; weight; densitometry; tibia; fibula; osteoporosis; egg shell; egg shell thickness; rapid methods; ash content; selection criteria
Abstract:
... Dual-energy X-ray absorptiometry can be used as a noninvasive tool to monitor the skeletal integrity of live birds. A pDexa X-ray bone densitometer was used to determine bone mineral densities (BMD) of the left tibia together with the fibula and the humerus of live, unanesthetized birds. Densitometry effectively detected changes in bone integrity of live birds fed varying levels of dietary calcium ...
DOI:
10.1093/ps/83.2.215
PubMed:
14979572

21. Association of CYP19 Gene Polymorphism with Vertebral Fractures in Japanese Postmenopausal Women

Author:
Yasuko Koudu; Tsuneko Onouchi; Takayuki Hosoi; Toshiyuki Horiuchi
Source:
Biochemical genetics 2012 v.50 no.5-6 pp. 389-396
ISSN:
0006-2928
Subject:
bone density; bone strength; gender differences; genes; genetic polymorphism; postmenopause; risk; testosterone; women
Abstract:
... This study investigates aromatase gene polymorphism, which might influence bone strength in terms of mineral density and quality. We explored the relationship between CYP19 polymorphisms and vertebral fractures in postmenopausal Japanese women. In addition, we compared estrogen and testosterone levels in Japanese postmenopausal women with and without fractures. Osteoporotic postmenopausal women sh ...
DOI:
10.1007/s10528-011-9483-z
PubMed:
22160249

22. Association of Dairy Food Intake with Measures of Bone Microarchitecture in Men and Women from the Framingham Study (OR18-08-19)

Author:
Shivani Sahni; Douglas Kiel; Marian Hannan
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
bone density; bone strength; calcium; cheeses; computed tomography; cream; cross-sectional studies; elderly; energy intake; food frequency questionnaires; longitudinal studies; men; milk; milk consumption; physical activity; progeny; regression analysis; tibia; vitamin D; vitamin supplements; women; yogurt
Abstract:
... Previous studies reported that dairy foods are associated with higher areal bone mineral density (BMD) in older adults. However, data on bone strength and bone microarchitecture are lacking. The objective of this study was to determine the association of milk, yogurt, cheese, cream, milk + yogurt and milk + yogurt + cheese intakes with high resolution peripheral quantitative computed tomography (H ...
DOI:
10.1093/cdn/nzz028.OR18-08-19

23. Beneficial effects of paeoniflorin on osteoporosis induced by high-carbohydrate, high-fat diet-associated hyperlipidemia in vivo

Author:
Yanmao Wang; Yu Zhu; Shengdi Lu; Chengfang Hu; Wanrun Zhong; Yimin Chai
Source:
Biochemical and biophysical research communications 2018 v.498 no.4 pp. 981-987
ISSN:
0006-291X
Subject:
adverse effects; biomechanics; blood lipids; blood serum; bone density; bone metabolism; bone strength; chemical constituents of plants; femur; high fat diet; hyperlipidemia; lipid composition; low density lipoprotein cholesterol; medicinal properties; micro-computed tomography; osteoblasts; osteoporosis; protective effect; rats; risk factors; triacylglycerols
Abstract:
... Osteoporosis is linked to reduced bone mineral density (BMD) as a major risk factor for fragility fractures. Recent studies indicated an association between BMD and abnormally elevated lipid levels in blood as common indicators for hyperlipidemia. In this study, we assessed the protective effect of paeoniflorin, a phytochemical compound with multiple pharmacological activities, against hyperlipide ...
DOI:
10.1016/j.bbrc.2018.03.093

24. Blueberry prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis

Author:
Devareddy, Latha; Hooshmand, Shirin; Collins, Julie K.; Lucas, Edralin A.; Chai, Sheau C.; Arjmandi, Bahram H.
Source:
Journal of nutritional biochemistry 2008 v.19 no.10 pp. 694-699
ISSN:
0955-2863
Subject:
osteocalcin; bone density; bone mineralization; blood chemistry; biomarkers; bone strength; functional foods; messenger RNA; collagen; ovariectomy; osteoporosis; rats; bone resorption; acid phosphatase; dosage; animal models; skeleton; blueberries; femur; alkaline phosphatase
Abstract:
... The objective of the present study was to explore the bone protective role of blueberry in an ovariectomized rat model. Thirty 6-month-old female Sprague-Dawley rats were either sham-operated (Sham) or ovariectomized (Ovx) and divided into three groups: Sham, Ovx (control), Ovx+blueberry (5% blueberry w/w). After 100 days of treatment, rats were euthanized, and blood and tissues were collected. Bo ...
DOI:
10.1016/j.jnutbio.2007.09.004
PubMed:
18328688

25. Bone Strength in Growing Rats Treated with Fluoride: a Multi-dose Histomorphometric, Biomechanical and Densitometric Study

Author:
Brenda Lorena Fina; Maela Lupo; Eugenia Rocío Da Ros; Mercedes Lombarte; Alfredo Rigalli
Source:
Biological trace element research 2018 v.185 no.2 pp. 375-383
ISSN:
0163-4984
Subject:
adults; biomechanics; bone density; bone strength; children; deformation; densitometry; femur; fluorides; fluorosis; laboratory animals; modulus of elasticity; multivariate analysis; rats; tibia
Abstract:
... Bone deformation and fragility are common signs of skeletal fluorosis. Disorganisation of bone tissue and presence of inflammatory foci were observed after fluoride (F⁻) administration. Most information about F⁻ effects on bone has been obtained in adult individuals. However, in fluorosis areas, children are a population very exposed to F⁻ and prone to develop not only dental but also skeletal flu ...
DOI:
10.1007/s12011-017-1229-2

26. Bone breaking strength and apparent metabolisability of calcium and phosphorus in selected and unselected broiler chicken genotypes

Author:
McDevitt, R.M.; McEntee, G.M.; Rance, K.A.
Source:
British poultry science 2006 v.47 no.5 pp. 613-621
ISSN:
0007-1668
Subject:
broiler chickens; broiler feeding; genotype; genetic variation; calcium; phosphorus; dietary minerals; nutritional status; mineral metabolism; bone strength; bone density; artificial selection; selection criteria; limb bones; body weight; chemical composition; nutrient intake; feed quality
Abstract:
... 1. The present study examined the bone strength and apparent mineral metabolisability of a selected broiler chicken compared with those of a relatively unselected genotype. 2. Selected (SB) and unselected genotypes (UB) were reared under standard conditions and were fed on either a high quality (HQ) or a low quality (LQ) diet. Tibiotarsi samples were collected at 42 d from SB and compared to tibio ...
DOI:
10.1080/00071660600963560
PubMed:
17050107

27. Bone densitometry as an indicator of percentage tibia ash in broiler chicks fed varying dietary calcium and phosphorus levels

Author:
Onyango, E.M.; Hester, P.Y.; Stroshine, R.; Adeola, O.
Source:
Poultry science 2003 v.82 no.11 pp. 1787-1791
ISSN:
0032-5791
Subject:
bone density; phosphorus; chicks; broiler chickens; dose response; liveweight gain; mineral content; broiler feeding; bone strength; shear strength; densitometry; tibia; calcium; nutrient deficiencies; feed conversion; equations; feed intake; prediction; nutritional status; dosage; ash content; dietary minerals
Abstract:
... The relative sensitivity of tibia bone mineral content (BMC) and density (BMD), percentage ash (ash), and shear force as indicators for dietary Ca and P was compared in 3-wk-old broiler chicks. One hundred eight 7-d-old chicks were grouped by weight into 6 blocks of 3 cages each with 6 birds per cage. Three corn-soybean meal-based diets were randomly assigned to cages within each block. The diets ...
DOI:
10.1093/ps/82.11.1787
PubMed:
14653474

28. Bone mineral density QTL at sexual maturity and end of lay

Author:
B.K. Podisi; S.A. Knott; I.C. Dunn; D.W. Burt; P.M. Hocking
Source:
British poultry science 2012 v.53 no.6 pp. 763-769
ISSN:
1466-1799
Subject:
White Leghorn; alleles; bone density; bone strength; chromosomes; crossing; laying hens; mutation; quantitative trait loci; selection criteria; sexual maturity
Abstract:
... 1. An F₂ cross of a broiler male line and a White Leghorn layer line was used to identify quantitative trait loci (QTL) for bone density at the onset of lay and at the end of the laying period. A total of 686 measures of humeral bone density were available for analysis.2. There was no evidence for epistasis.3. Genome-wide significant QTL for bone density at the onset of lay were identified on chro ...
DOI:
10.1080/00071668.2012.747674
PubMed:
23398420

29. Bone strength of caged layers as affected by dietary calcium and phosphorus concentrations, reconditioning, and ash content

Author:
Wilson, J.H.
Source:
British poultry science 1991 v.32 no.3 pp. 501-508
ISSN:
0007-1668
Subject:
hens; bone strength; shear strength; body weight; bone density
DOI:
10.1080/00071669108417374
PubMed:
1893262

30. Bone structure and breaking strength in laying hens housed in different husbandry systems

Author:
Fleming, R.H.; Whitehead, C.C.; Alvey, D.; Gregory, N.G.; Wilkins, L.J.
Source:
British poultry science 1994 v.35 no.5 pp. 651-662
ISSN:
0007-1668
Subject:
perches (animal housing); battery husbandry; radiography; tibia; humerus; bone fractures; physical activity; battery cages; bone formation; bone density; osteoporosis; hens; bone strength
Abstract:
... 1. Bone structure and breaking strength were measured in hens that had been housed throughout a laying year in battery cages or in Perchery, Naturel or Litter and Wire husbandry systems. 2. Battery caged hens had the poorest bones, as assessed by measurements of cancellous bone volume, radiographic density, cortical thickness and three-point breaking strength. 3. Humeri from birds in the Litter an ...
DOI:
10.1080/00071669408417731
PubMed:
7719730

31. Bone-protective effects of bioactive fractions and ingredients in Sambucus williamsii HANCE

Author:
Hui-Hui Xiao; Yi Dai; Hoi-Ying Wan; Man-Sau Wong; Xin-Sheng Yao
Source:
British journal of nutrition 2011 v.106 no.12 pp. 1802-1809
ISSN:
1475-2662
Subject:
Sambucus; bioactive properties; biomechanics; bone density; bone strength; cell proliferation; ethanol; femur; high performance liquid chromatography; ingredients; lignans; mice; models; phenolic acids; rats; tibia; uterus
Abstract:
... Our previous study demonstrated that 60 % ethanol crude extract of Sambucus williamsii HANCE (SWH) improved bone mass, bone strength and bone micro-structure in both ovariectomised (OVX) rats and mice. The present study aims to identify the bioactive fractions and ingredients in SWH that account for its osteoprotective effects. Bilateral sham-operated mice acted as controls. OVX C57BL/6J mice, age ...
DOI:
10.1017/S0007114511002546
PubMed:
21736773

32. Boron and fish oil have different beneficial effects on strength and trabecular microarchitecture of bone

Author:
Nielsen, Forrest H.; Stoecker, Barbara J.
Source:
Journal of trace elements in medicine and biology 2009 v.23 no.3 pp. 195-203
Subject:
nutrient intake; skeletal development; food intake; linoleic acid; vertebrae; nutrient availability; boron; bone density; rats; safflower oil; bone strength; femur; menhaden oil
Abstract:
... An experiment was performed to determine whether boron deprivation would adversely affect vertebra (trabecular) bone microarchitecture, and whether any adverse effect would be modified by dietary fatty acid composition. Female rats were fed diets containing 0.1 mg (9 μmol) boron/kg in a factorial arrangement with variables of supplemental boron at 0 (boron-deprived) or 3 (boron-adequate) mg (278 μ ...
Handle:
10113/46624
DOI:
10.1016/j.jtemb.2009.03.003

33. Calcium Requirements of Growing Rats Based on Bone Mass, Structure, or Biomechanical Strength Are Similar

Author:
Hunt, Janet R.; Hunt, Curtiss D.; Zito, Carol Ann; Idso, Joseph P.; Johnson, LuAnn K.
Source:
Journal of nutrition 2008 v.138 no.8 pp. 1462-1468
ISSN:
0022-3166
Subject:
calcium; dietary minerals; nutrient requirements; animal models; animal growth; bone density; bone fractures; bone strength; animal morphology; tibia; rats; food intake; experimental diets
Abstract:
... Although calcium (Ca) supplementation increases bone density, the increase is small and the effect on bone strength and fracture risk is uncertain. To investigate if bone mass, morphology, and biomechanical properties are affected by deficient to copious dietary Ca concentrations, the long bones (tibia and femur) of growing female Sprague-Dawley rats (8/group) were assessed after 13 wk of consumin ...
Handle:
10113/23503
PubMed:
18641192

34. Calcium Supplement Derived from Gallus gallus domesticus Promotes BMP-2/RUNX2/SMAD5 and Suppresses TRAP/RANK Expression through MAPK Signaling Activation

Author:
Han Seok Yoo; Gyung-Ji Kim; Da Hye Song; Kang-Hyun Chung; Kwon-Jai Lee; Dong-Hee Kim; Jeung Hee An
Source:
Nutrients 2017 v.9 no.5 pp. -
ISSN:
2072-6643
Subject:
Gallus gallus; bone density; bone formation; bone morphogenetic proteins; bone resorption; bone strength; calcium; cathepsin K; chickens; diet; genes; genetic markers; micro-computed tomography; mitogen-activated protein kinase; mothers against decapentaplegic homolog proteins; osteoblasts; osteocalcin; osteoclasts; ovariectomy; rats; tibia; transcription factor NF-kappa B
Abstract:
... The present study evaluated the effects of a calcium (Ca) supplement derived from Gallus gallus domesticus (GD) on breaking force, microarchitecture, osteogenic differentiation and osteoclast differentiation factor expression in vivo in Ca-deficient ovariectomized (OVX) rats. One percent of Ca supplement significantly improved Ca content and bone strength of the tibia. In micro-computed tomography ...
DOI:
10.3390/nu9050504
PubMed:
28513557
PubMed Central:
PMC5452234

35. Carfilzomib alleviated osteoporosis by targeting PSME1/2 to activate Wnt/β-catenin signaling

Author:
Fan Zhang; Shokouh Attarilar; Kegong Xie; Chao Han; Qingyang liang; Ke Huang; Changgong Lan; Chong Wang; Chengliang Yang; Liqiang Wang; Masoud Mozafari; Kai Li; Jia Liu; Yujin Tang
Source:
Molecular and cellular endocrinology 2022 v.540 pp. 111520
ISSN:
0303-7207
Subject:
bone density; bone formation; bone strength; endocrinology; micro-computed tomography; models; osteoblasts; osteoclasts; osteoporosis; ovariectomy; postmenopause; proteasome endopeptidase complex; proteasome inhibitors; protein content; recombinant proteins
Abstract:
... Osteoporosis (OP) is characterized by decreased bone mineral density and impaired bone strength. Carfilzomib (CFZ) is a new-generation proteasome inhibitor and has been found to affect bone metabolism. However, the effect and mechanism of CFZ on OP has not been investigated systematically. In this study, we found that protein levels of proteasome activator subunit 1/2 (PSME1/2) increased in OP, an ...
DOI:
10.1016/j.mce.2021.111520

36. Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality

Author:
Tanis R Fenton; Suzanne C Tough; Andrew W Lyon; Misha Eliasziw; David A Hanley
Source:
Nutrition journal 2011 v.10 no.1 pp. 371
ISSN:
1475-2891
Subject:
acid ash diet; adults; balance studies; biopsy; bone density; bone strength; calcium; dietary supplements; estrogens; excretion; grain foods; in vitro studies; meta-analysis; milk; osteoporosis; pH; phosphates; prospective studies; risk factors; systematic review; urine; weight loss
Abstract:
... BACKGROUND: Modern diets have been suggested to increase systemic acid load and net acid excretion. In response, alkaline diets and products are marketed to avoid or counteract this acid, help the body regulate its pH to prevent and cure disease. The objective of this systematic review was to evaluate causal relationships between dietary acid load and osteoporosis using Hill's criteria. METHODS: S ...
DOI:
10.1186/1475-2891-10-41
PubMed:
21529374
PubMed Central:
PMC3114717

37. Changes in bone mass, biomechanical properties, and microarchitecture of calcium- and iron-deficient rats fed diets supplemented with inulin-type fructans

Author:
Lobo, Alexandre R.; Cocato, Maria Lucia; Jorgetti, Vanda; de Sá, Lílian R.M.; Nakano, Eduardo Y.; Colli, Célia
Source:
Nutrition research 2009 v.29 no.12 pp. 873-881
ISSN:
0271-5317
Subject:
bone density; bone mineralization; transferrin; males; binding proteins; bone strength; microstructure; dietary fiber; blood serum; tibia; calcium; nutrient deficiencies; histology; iron deficiency anemia; rats; inulin; bone resorption; heme iron; osteoclasts; liver; mineral metabolism; nutritional status; experimental diets; nutrient availability; hemoglobin; magnesium; animal models
Abstract:
... Feeding mineral-deficient diets enhances absorptive efficiency as an attempt of the body to compensate for the lack of an essential nutrient. Under certain circumstances, it does not succeed; and nutritional deficiency is produced. Our hypothesis was that inulin-type fructans (ITF), which are known to affect mineral absorption, could increase Ca and Fe bioavailability in Ca- and Fe-deficient rats. ...
DOI:
10.1016/j.nutres.2009.10.012
PubMed:
19963161

38. Changes in bone structure of Corriedale sheep with inherited rickets: A peripheral quantitative computed tomography assessment

Author:
Keren E. Dittmer; Elwyn C. Firth; Keith G. Thompson; Jonathan C. Marshall; Hugh T. Blair
Source:
veterinary journal 2011 v.187 no.3 pp. 369-373
ISSN:
1090-0233
Subject:
Corriedale; bone density; bone strength; computed tomography; mineral content; rickets; sheep; tibia; New Zealand
Abstract:
... An inherited skeletal disease with gross and microscopic features of rickets has been diagnosed in Corriedale sheep in New Zealand. The aim of this study was to quantify the changes present in tibia from sheep with inherited rickets using peripheral quantitative computed tomography. In affected sheep, scans in the proximal tibia, where metaphysis becomes diaphysis, showed significantly greater tra ...
DOI:
10.1016/j.tvjl.2009.12.025

39. Changes of lipid and bone metabolism in broilers with spontaneous femoral head necrosis

Author:
Kangping Liu; Kuanbo Wang; Leguo Wang; Zhenlei Zhou
Source:
Poultry science 2021 v.100 no.3 pp. 100808
ISSN:
0032-5791
Subject:
alanine transaminase; alkaline phosphatase; apoptosis; aspartate transaminase; blood chemistry; bone density; bone metabolism; bone strength; cartilage; chondrocytes; comparative study; etiology; femur; growth plate; high density lipoprotein; homeostasis; hyperlipidemia; lipid metabolism; liver; liver function; necrosis; tibia; triacylglycerols
Abstract:
... Blood biochemistry and bone metabolism were evaluated to investigate the etiology and mechanism of spontaneous femoral head necrosis (FHN) in broilers. According to the femoral head score of the fourth, fifth, and sixth week old FHN-affected broilers, they were divided into 3 groups, namely Normal group, femoral head separation group, and femoral head separation with growth plate lacerations group ...
DOI:
10.1016/j.psj.2020.10.062

40. Characteristics of kyphotic vertebrae in the cultured yellowtail Seriola quinqueradiata

Author:
Daichi Hayashi; Chiemi Miura; Takeshi Miura
Source:
Aquaculture 2019 v.506 pp. 380-386
ISSN:
0044-8486
Subject:
Seriola quinqueradiata; X-radiation; ash content; bone density; bone strength; farmers; financial economics; fish; histology; image analysis; muscles; porosity; spermatogenesis; vertebrae
Abstract:
... Vertebral deformities, including kyphosis, of the cultured yellowtail Seriola quinqueradiata resulted in a decrease in product value, and consequently economic loss for fish farmers. Hence, in order to resolve this problem, it is important to examine the characteristics of kyphotic vertebrae in fish. In this study, we focused on the comparison between kyphotic and non-kyphotic two-year old yellowt ...
DOI:
10.1016/j.aquaculture.2019.03.071

41. Citrus juice modulates bone strength in male senescent rat model of osteoporosis

Author:
Deyhim, F.; Garcia, K.; Lopez, E.; Gonzalez, J.; Ino, S.; Garcia, M.; Patil, B.S.
Source:
Nutrition 2006 v.22 no.5 pp. 559-563
ISSN:
0899-9007
Subject:
bone metabolism; disease prevention; males; orange juice; bone density; animal models; osteoporosis; rats; Citrus; antioxidant activity; bone strength; grapefruit juice; antioxidants; oxidative stress
DOI:
10.1016/j.nut.2005.12.002
PubMed:
16472977

42. Comparative Activities of the S-Enantiomer and Racemic Forms of Equol on Bone Fragility in Ovariectomized Mice

Author:
Yoshifumi KIMIRA; Shin-ichi KATSUMATA; Kazuharu SUZUKI; Yoshiko ISHIMI; Tomomi UENO; Shigeto UCHIYAMA; Herman ADLERCREUTZ; Mariko UEHARA
Source:
Bioscience, biotechnology, and biochemistry 2012 v.76 no.5 pp. 1018-1021
ISSN:
1347-6947
Subject:
biochemistry; biotechnology; blood serum; bone density; bone strength; femur; ovariectomy; urine
Abstract:
... We compared the effects of the S-enantiomer and racemic forms of equol on bone using ovariectomized (OVX) mice. Femoral bone mineral density and bone strength decreased in the OVX mice, but not in OVX mice administered 0.5 mg/d S-equol. This, however, did not hold for racemic equol. Serum and urine S-equol concentrations were higher in the mice administered S-equol than in those administered racem ...
DOI:
10.1271/bbb.110973

43. Comparative differences in the composition and biomechanical properties of tibiae of seven- and seventy-two-week-old male and female broiler breeder chickens

Author:
Rath, N.C.; Balog, J.M.; Huff, W.E.; Huff, G.R.; Kulkarani, G.B.; Tierce, J.F.
Source:
Poultry science 1999 v.78 no.8 pp. 1232-1239
ISSN:
0032-5791
Subject:
broiler chickens; hens; roosters; gender differences; tibia; epiphyses; bone density; histology; blood glucose; blood lipids; calcium; phosphorus; blood serum; alkaline phosphatase; creatine kinase; lactate dehydrogenase; bone strength; collagen; proteoglycans; fluorescence
Abstract:
... Skeletal problems are common in both young and old poultry and are often related to bone weakness. They affect mortality on the farm and condemnations within processing plant and thus raise both welfare and economic concerns. To understand the basis of bone strength, the metaphyseal histology, composition, and the biomechanical properties of tibiae from 7- and 72-wk-old male and female broiler bre ...
DOI:
10.1093/ps/78.8.1232
PubMed:
10472852

44. Comparison of bones of 4 strains of laying hens kept in conventional cages and floor pens

Author:
F. G. Silversides; R. Singh; K. M. Cheng; D. R. Korver
Source:
Poultry science 2012 v.91 no.1 pp. 1-7
ISSN:
0032-5791
Subject:
Plymouth Rock; Rhode Island Red; White Leghorn; animal health; animal pens; animal welfare; bone density; bone strength; cages; crossbreds; genetic background; laying hens; mechanical loads; nest boxes; radius (bone); restraint of animals; strain differences; tibia; wings
Abstract:
... The maintenance of bone strength has been an important issue in the debate over cage use for laying hens. Bone strength depends on adequate mechanical load and cages restrict movement. Four laying crosses (Lohmann White, Lohmann Brown, H&N White, and Rhode Island Red x Barred Plymouth Rock cross hens) were housed in conventional cages or in floor pens equipped with perches and nest boxes to measur ...
DOI:
10.3382/ps.2011-01453
PubMed:
22184423

45. Comprehensive evaluation of the combined extracts of Epimedii Folium and Ligustri Lucidi Fructus for PMOP in ovariectomized rats based on MLP-ANN methods

Author:
Zitong Ma; Xiaoxi Li; Yuheng Chen; Xiufeng Tang; Yingying Gao; Han Wang; Renhui Liu
Source:
Journal of ethnopharmacology 2021 v.268 pp. 113563
ISSN:
0378-8741
Subject:
Oriental traditional medicine; bone density; bone strength; estrogens; humans; immunity; kidneys; metabolism; microstructure; models; nerve tissue; osteoporosis; ovariectomy; pathogenesis; postmenopause
Abstract:
... Kidney deficiency is the main pathogenesis of osteoporosis based on the theory of “kidney governing bones” in traditional Chinese medicine (TCM). Osteoporosis is a systemic disease; kidney deficiency influences the growth, aging and reproduction of human body, reflecting in endocrine, nerve, immunity, metabolism and other functions. Multi-target drugs composed of natural non-toxic products from ki ...
DOI:
10.1016/j.jep.2020.113563

46. Cortical bone development, maintenance and porosity: genetic alterations in humans and mice influencing chondrocytes, osteoclasts, osteoblasts and osteocytes

Author:
Tsuyoshi Isojima; Natalie A. Sims
Source:
Cellular and molecular life sciences 2021 v.78 no.15 pp. 5755-5773
ISSN:
1420-682X
Subject:
bone density; bone mineralization; bone resorption; bone strength; chondrocytes; cortex; humans; mice; mineralization; osteoblasts; osteoclasts; porosity; skeletal development; wnt proteins
Abstract:
... Cortical bone structure is a crucial determinant of bone strength, yet for many years studies of novel genes and cell signalling pathways regulating bone strength have focused on the control of trabecular bone mass. Here we focus on mechanisms responsible for cortical bone development, growth, and degeneration, and describe some recently described genetic-driven modifications in humans and mice th ...
DOI:
10.1007/s00018-021-03884-w

47. Dairy Food Intake Is Not Associated with Measures of Bone Microarchitecture in Men and Women: The Framingham Osteoporosis Study

Author:
Courtney L. Millar; Douglas P. Kiel; Marian T. Hannan; Shivani Sahni
Source:
Nutrients 2021 v.13 no.11 pp. -
ISSN:
2072-6643
Subject:
bone density; bone strength; cheeses; computed tomography; cross-sectional studies; dairy consumption; energy; food frequency questionnaires; milk; osteoporosis; regression analysis; tibia; yogurt
Abstract:
... Previous studies reported that dairy foods are associated with higher areal bone mineral density (BMD) in older adults. However, data on bone strength and bone microarchitecture are lacking. We determined the association of dairy food intake (milk, yogurt, cheese, milk + yogurt, and milk + yogurt + cheese, servings/week) with high resolution peripheral quantitative computed tomography (HR-pQCT) me ...
DOI:
10.3390/nu13113940

48. Dietary Advanced Glycation End-Products (dAGEs) Intake and Bone Health: A Cross-Sectional Analysis in the Rotterdam Study

Author:
Komal Waqas; Jinluan Chen; Bram C. J. van der Eerden; M. Arfan Ikram; André G. Uitterlinden; Trudy Voortman; M. Carola Zillikens
Source:
Nutrients 2020 v.12 no.8 pp. -
ISSN:
2072-6643
Subject:
advanced glycation end products; age; bone density; bone health; bone strength; cross-sectional studies; diabetes; energy intake; femur; food intake; food quality; frequency; glycation; hips; humans; humerus; lumbar spine; odds ratio; physical activity; regression analysis; renal function
Abstract:
... Animal studies suggest a role for dietary advanced glycation end-products (dAGEs) in bone health, but human studies on dAGEs in relation to bone are lacking. We aimed to study whether dAGEs intake is associated with the parameters of bone strength namely, bone mineral density (BMD), prevalent vertebral (VFs), and major osteoporotic fractures (MOFs = hip, wrist, proximal humerus, and clinical VFs). ...
DOI:
10.3390/nu12082377

49. Dietary Calcium Restriction Affects Mesenchymal Stem Cell Activity and Bone Development in Neonatal Pigs

Author:
Mahajan, Avanika; Alexander, Lindsey S.; Seabolt, Brynn S.; Catrambone, Daniel E.; McClung, James P.; Odle, Jack; Pfeiler, T. Wayne; Loboa, Elizabeth G.; Stahl, Chad H.
Source:
Journal of nutrition 2011 v.141 no.3 pp. 373-379
ISSN:
0022-3166
Subject:
bone density; bone strength; calcium; diet; dietary restriction; in vitro studies; long term effects; neonatal development; parathyroid hormone; phosphates; skeletal development; stem cells; swine
Abstract:
... The effects of dietary calcium (Ca) deficiency on skeletal integrity are well characterized in growing and mature mammals; however, less is known about Ca nutrition during the neonatal period. In this study, we examined the effects of neonatal Ca nutrition on bone integrity, endocrine hormones, and mesenchymal stem cell (MSC) activity. Neonatal pigs (24 ± 6 h of age) received either a Ca-adequate ...
DOI:
10.3945/jn.110.131193
PubMed:
21248192

50. Dietary Protein Derived from Dried Bonito Fish Improves Type‐2 Diabetes Mellitus‐Induced Bone Frailty in Goto‐Kakizaki Rats

Author:
Masaru Ochiai; Takashi Kuroda; Shoichi Gohtani; Tatsuhiro Matsuo
Source:
Journal of food science 2015 v.80 no.4 pp. H848
ISSN:
0022-1147
Subject:
bonito; food intake; young animals; blood chemistry; blood serum; polyunsaturated fatty acids; absorption; calcium; bone density; casein; noninsulin-dependent diabetes mellitus; rats; femur; bone strength; alkaline phosphatase
Abstract:
... Type‐2 diabetes mellitus (T2DM) induces bone frailty. Protein and polyunsaturated fatty acids (PUFA) contained in fish can be effective in enhancing bone quality, but the bone developing effect of fish protein containing less PUFA has not been evaluated in young animals with T2DM. We prepared a bonito fish (BF) and defatted BF (DBF) and hypothesized that protein contained in BF and DBF would be ef ...
DOI:
10.1111/1750-3841.12797

51. Dietary betaine reduces plasma homocysteine concentrations and improves bone strength in laying hens

Author:
M. B. M. Maidin; H. A. McCormack; P. W. Wilson; S. D. Caughey; N. Whenham; I. C. Dunn
Source:
British poultry science 2021 v.62 no.4 pp. 573-578
ISSN:
1466-1799
Subject:
betaine; bone density; bone mineralization; bone strength; egg production; homocysteine; phosphorus; phytases; tibia
Abstract:
... 1. This study tested the hypothesis that the methyl-donor properties of betaine could reduce homocysteine concentrations, which has been recognised in a previous genetics study to be linked to bone quality. This was combined with phytase treatment, as phosphorus is critical for bone mineralisation. 2. Using a 2 × 2 factorial arrangement, a total of 1920 Lohmann LSL-lite chickens housed as 24 repli ...
DOI:
10.1080/00071668.2021.1883550

52. Dietary non-phytate phosphorus requirement of broilers fed a conventional corn-soybean meal diet from 1 to 21 d of age

Author:
S.B. Liu; X.D. Liao; L. Lu; S.F. Li; L. Wang; L.Y. Zhang; Y. Jiang; X.G. Luo
Source:
Poultry science 2017 v.96 no.1 pp. 151-159
ISSN:
0032-5791
Subject:
blood serum; bone density; bone strength; cages; calcium; calcium hydrogen phosphate; diet; duodenum; gene expression; genes; growth performance; inorganic phosphorus; males; sodium phosphate; symporters; tibia; weight gain
Abstract:
... An experiment was conducted to investigate the effect of dietary non-phytate phosphorus (NPP) level on growth performance, bone characteristics and phosphorus metabolism-related gene expressions, so as to evaluate the dietary NPP requirement of broiler chicks fed a conventional corn-soybean meal diet from 1 to 21 d of age. A total of 540 day-old Arbor Acres male chicks were randomly allocated to o ...
DOI:
10.3382/ps/pew212

53. Dietary patterns and incident low-trauma fractures in postmenopausal women and men aged ≥50 y: a population-based cohort study

Author:
Langsetmo, Lisa; Hanley, David A.; Prior, Jerilynn C.; Barr, Susan I.; Anastassiades, Tassos; Towheed, Tanveer; Goltzman, David; Morin, Suzanne; Poliquin, Suzette; Kreiger, Nancy
Source:
American journal of clinical nutrition 2011 v.93 no.1 pp. 192-199
ISSN:
0002-9165
Subject:
vegetables; bone fractures; energy density; age; bone density; French fries; food frequency questionnaires; potato chips; bone mineralization; meat products; sweets; women; menopause; bone strength; men; nutrient density; osteoporosis; body mass index; soft drinks; whole grain foods
Abstract:
... BACKGROUND: Previous research has shown that dietary patterns are related to the risk of several adverse health outcomes, but the relation of these patterns to skeletal fragility is not well understood. OBJECTIVE: Our objective was to determine the relation between dietary patterns and incident fracture and possible mediation of this relation by body mass index, bone mineral density, or falls. DES ...
DOI:
10.3945/ajcn.110.002956
PubMed:
21068350
PubMed Central:
PMC5101071

54. Dietary supplementation with dried plum prevents ovariectomy-induced bone loss while modulating the immune response in C57BL/6J mice

Author:
Elizabeth Rendina; Yin F. Lim; Denver Marlow; Yan Wang; Stephen L. Clarke; Solo Kuvibidila; Edralin A. Lucas; Brenda J. Smith
Source:
Journal of nutritional biochemistry 2012 v.23 no.1 pp. 60-68
ISSN:
0955-2863
Subject:
animal ovaries; bone density; bone marrow; bone resorption; bone strength; dietary supplements; immune response; mice; necrosis; plums; tibia; tumor necrosis factors
Abstract:
... This study was designed to investigate the effects of dried plum on the changes in bone metabolism and the immune response associated with ovarian hormone deficiency. Adult female C57BL/6J mice were either sham-operated (Sham) and fed AIN-93 diet (control) or ovariectomized (OVX) and fed a control diet with 0%, 5%, 15% or 25% dried plum (w/w), corresponding to control, low- (LDP), medium- (MDP) an ...
DOI:
10.1016/j.jnutbio.2010.10.010
PubMed:
21414765

55. Dioscorea improves the morphometric and mechanical properties of bone in ovariectomised rats

Author:
Chen, Jian-Horng; Wu, James Shih-Shyn; Lin, Hsiao-Che; Wu, Shey-Lin; Wang, Wen-Fu; Huang, Shu-Kuei; Ho, Ying-Jui
Source:
Journal of the science of food and agriculture 2008 v.88 no.15 pp. 2700-2706
ISSN:
0022-5142
Subject:
food intake; Dioscorea alata; porosity; mineral content; ovariectomy; mechanical properties; bone density; animal models; osteoporosis; rats; bone strength; oral administration; roots; femur; yams
Abstract:
... BACKGROUND: The aim of this work was to determine the effects of oral administration of dioscorea on the morphometric and mechanical properties of the femur in ovariectomised (OVX) rats. Female Wistar rats that had undergone surgery for ovariectomy were used as a model of menopause and osteoporosis. Four weeks after surgery the animals were given oral dioscorea (0, 250, 750 or 1500 mg kg⁻¹ day⁻¹) ...
DOI:
10.1002/jsfa.3396

56. Disruption of bone morphogenetic protein type IA receptor in osteoblasts impairs bone quality and bone strength in mice

Author:
Quanwei Bao; Ang Li; Sixu Chen; Jianquan Feng; Huayu Liu; Hao Qin; Junfeng Li; Daocheng Liu; Yue Shen; Zhaowen Zong
Source:
Cell and tissue research 2018 v.374 no.2 pp. 263-273
ISSN:
0302-766X
Subject:
bone density; bone morphogenetic proteins; bone strength; collagen; culture media; femur; immunohistochemistry; in vivo studies; mice; mineralization; osteoblasts; osteocalcin
Abstract:
... In recent years, several studies have found that the disruption of type IA receptor of bone morphogenetic proteins (BMPR1A) could increase bone mass. However, whether disruption of BMPR1A could have an effect on bone quality and bone strength is currently unknown. Osteoblast-targeted conditional knockout (cKO) of BMPRIA by crossing 3.2-kb Col1-CreER™ mice with BMPR1A fx +/+ mice was conducted. The ...
DOI:
10.1007/s00441-018-2873-3

57. Drynaria fortunei J. Sm. improves the bone mass of ovariectomized rats through osteocalcin-involved endochondral ossification

Author:
Yong-Eng Lee; Hwa-Chang Liu; Yi-Ling Lin; Shing-Hwa Liu; Rong-Sen Yang; Ruei-Ming Chen
Source:
Journal of ethnopharmacology 2014 v.158 pp. 94-101
ISSN:
0378-8741
Subject:
Drynaria fortunei; bioactive compounds; biomechanics; biosynthesis; blood serum; body weight; bone density; bone formation; bone strength; chondrocytes; estradiol; growth plate; immunoblotting; immunohistochemistry; mineral content; naringin; osteoblasts; osteocalcin; ovariectomy; rats; traditional medicine; translation (genetics)
Abstract:
... Our previous study showed that Drynaria fortunei J. Sm. (Kunze), a traditional Chinese medical herb, can promote osteoblast differentiation and maturation. This study was further aimed to confirm the traditional effects of Kunze on the bone mass of ovariectomized rats.Female Wistar rats were given an ovariectomy and then administered the water extract of Kunze (WEK). Systemic and tissue toxicities ...
DOI:
10.1016/j.jep.2014.10.016

58. Early life vitamin D depletion and mechanical loading determine methylation changes in the RUNX2, RXRA, and osterix promoters in mice

Author:
Nevena Krstic; Nick Bishop; Beth Curtis; Cyrus Cooper; Nick Harvey; Karen Lilycrop; Robert Murray; Robert Owen; Gwen Reilly; Tim Skerry; Steph Borg
Source:
Genes & nutrition 2022 v.17 no.1 pp. 7
ISSN:
1555-8932
Subject:
DNA methylation; bone density; bone strength; diet; epigenome; growth and development; mice; osteoblasts; pregnancy; tibia
Abstract:
... BACKGROUND: Early life vitamin D exposure is linked to later skeletal health with maternal vitamin D status in pregnancy associated with neonatal bone mass. The MAVIDOS study has demonstrated that vitamin D supplementation leads to reduced RXRA DNA methylation. Mice exposed to early life vitamin D deficiency have reduced bone mass and bone accrual in response to mechanical loading. Using the tibia ...
DOI:
10.1186/s12263-022-00711-0

59. Effect of 12 months of creatine supplementation and whole-body resistance training on measures of bone, muscle and strength in older males

Author:
Darren G Candow; Philip D Chilibeck; Julianne Gordon; Emelie Vogt; Tim Landeryou; Mojtaba Kaviani; Lisa Paus-Jensen
Source:
Nutrition and health 2021 v.27 no.2 pp. 151-159
ISSN:
2047-945X
Subject:
bone density; bone resorption; creatine; femur; geometry; muscle strength; muscles; nutrition; placebos
Abstract:
... The combination of creatine supplementation and resistance training (10–12 weeks) has been shown to increase bone mineral content and reduce a urinary indicator of bone resorption in older males compared with placebo. However, the longer-term effects (12 months) of creatine and resistance training on bone mineral density and bone geometric properties in older males is unknown. To assess the effect ...
DOI:
10.1177/0260106020975247

60. Effect of Korean Oriental medicine extract on bone mass as compared with alendronate in ovariectomized rats

Author:
Lee, J.W.; Jhee, O.; Yuan, H.; Kim, T.; Kim, D.; Lee, M; Om, A.; Lee, B.; Park, S.K.; Kang, J.
Source:
Journal of medicinal food 2005 v.8 no.3 pp. 369-376
ISSN:
1096-620X
Subject:
alternative medicine; Oriental traditional medicine; plant extracts; drug formulations; medicinal plants; medicinal properties; osteoporosis; bone density; bone strength; protective effect; rats; animal disease models; females; calcium; dietary restriction; ovariectomy; biomarkers; histology
DOI:
10.1089/jmf.2005.8.369
PubMed:
16176149

61. Effect of Total Glycosides from Eucommia ulmoides Seed on Bone Microarchitecture in Rats

Author:
Yang Li; Min‐juan Wang; Sen Li; Yong‐min Zhang; Ye Zhao; Ren‐ming Xie; Wen‐ji Sun
Source:
Phytotherapy research 2011 v.25 no.12 pp. 1895-1897
ISSN:
0951-418X
Subject:
Eucommia ulmoides; alternative medicine; body weight; bone density; bone fractures; bone strength; femur; glycosides; herbs; oral administration; osteoporosis; rats; seed extracts; seeds; traditional medicine
Abstract:
... Du‐Zhong is one of the most important tonic herbs in traditional Chinese medicine for the treatment of bone fractures and other bone diseases. The present study examined whether Du‐Zhong seed extract named total glycosides from Eucommia ulmoides seed (TGEUS) could display an increased effect on bone density and bone strength of the femur in rats. Sprague–Dawley rats were used and randomly assigned ...
DOI:
10.1002/ptr.3543
PubMed:
21674630

62. Effect of daily lithium chloride administration on bone mass and strength in growing broiler chickens,

Author:
B.M. Harvey; M. Eschbach; E.A. Glynn; S. Kotha; M. Darre; D.J. Adams; R. Ramanathan; R. Mancini; K.E. Govoni
Source:
Poultry science 2015 v.94 no.2 pp. 296-301
ISSN:
0032-5791
Subject:
blood serum; body weight; bone density; bone strength; color; feed intake; femur; lipid peroxidation; lithium; lithium chloride; meat quality; mice; micro-computed tomography; modulus of elasticity; muscles; pectoralis muscle
Abstract:
... The objective was to determine the effects of oral lithium chloride supplementation on bone strength and mass in broiler chickens. Ninety-six broilers were assigned to 1 of 2 treatment groups (lithium chloride or control; n = 48/treatment). Beginning at 1 or 3 wk of age, chickens were administered lithium chloride (20 mg/kg body weight) or water daily by oral gavage. At 6 wk of age, chickens were ...
DOI:
10.3382/ps/peu079

63. Effect of dietary citric acid on the performance and mineral metabolism of broiler

Author:
K. M. S. Islam; H. Schaeublin; C. Wenk; M. Wanner; A. Liesegang
Source:
Journal of animal physiology and animal nutrition 2012 v.96 no.5 pp. 808-817
ISSN:
0931-2439
Subject:
acid insoluble ash; blood; bone density; bone strength; boning; broiler chickens; calcium; carcass quality; carcass weight; chicks; citric acid; diet; digestibility; feces; feed conversion; feed intake; finishing; magnesium; meat carcasses; mineral metabolism; minerals; pH; phosphorus; profits and margins; slaughter; tibia; weight gain
Abstract:
... The objective of this study was to investigate the effect of dietary citric acid (CA) on the performance and mineral metabolism of broiler chicks. A total of 1720 Ross PM3 broiler chicks (days old) were randomly assigned to four groups (430 in each) and reared for a period of 35 days. The diets of groups 1, 2, 3 and 4 were supplemented with 0%, 0.25%, 0.75% or 1.25% CA by weight respectively. Feed ...
DOI:
10.1111/j.1439-0396.2011.01225.x
PubMed:
22093035

64. Effect of glucocorticoid withdrawal on glucocorticoid inducing bone impairment

Author:
Gengyang Shen; Hui Ren; Ting Qiu; De Liang; Qiushi Wei; Jingjing Tang; Zhida Zhang; Zhensong Yao; Wenhua Zhao; Xiaobing Jiang
Source:
Biochemical and biophysical research communications 2016 pp. -
ISSN:
0006-291X
Subject:
absorption; biomechanics; blood serum; bone density; bone strength; dexamethasone; dual-energy X-ray absorptiometry; energy; females; osteoporosis; rats; therapeutics; vertebrae
Abstract:
... Glucocorticoid (GC) withdrawal after a short-term use was common in clinical practice like immediate post-transplant period. However, previous studies without setting age-control group failed to determine whether the BMD recovery was sufficient and whether it is necessary to accept anti-osteoporosis therapy after GC withdrawal. The aim of this study was to investigate the effect of GC withdrawal o ...
DOI:
10.1016/j.bbrc.2016.07.036

65. Effect of photoperiod on eggshell quality and quality characteristics of tibia, femur, and ulna in laying ducks

Author:
Yao-ming Cui; Jing Wang; Hai-jun Zhang; Guang-hai Qi; Shu-geng Wu
Source:
Poultry science 2021 v.100 no.10 pp. 101376
ISSN:
0032-5791
Subject:
blood serum; bone density; bone formation; bone strength; egg shell; egg shell quality; femur; interleukin-6; mineral content; resorption; tibia; ulna
Abstract:
... We investigated the effect of photoperiod on eggshell quality, bone quality characteristics and bone metabolism related enzymes and factors in laying ducks. After adaption, 300 Jinding laying ducks (252-day-old) were randomly divided into 5 treatments, receiving 12L (hours of light):12D (hours of darkness), 14L:10D, 16L:8D, 18L:6D or 20L:4D, respectively. Each group had 6 replicates of 10 birds ea ...
DOI:
10.1016/j.psj.2021.101376

66. Effects of 12 Months Consumption of 100 g Dried Plum (Prunes) on Bone Biomarkers, Density, and Strength in Men

Author:
Shirin Hooshmand; Danielle Gaffen; Ashley Eisner; Jonnatan Fajardo; Mark Payton; Mark Kern
Source:
Journal of medicinal food 2022 v.25 no.1 pp. 40-47
ISSN:
1557-7600
Subject:
alkaline phosphatase; biomarkers; blood; bone density; bone health; bone strength; collagen; computed tomography; diet; dual-energy X-ray absorptiometry; functional foods; hips; humans; males; plums; prunes; tibia; ulna
Abstract:
... Several male animal studies have demonstrated bone-protective effects of dried plum; however, no human male study has evaluated the effect of dried plum on bone health. We conducted a randomized controlled clinical study to test if daily inclusion of 100 g of dried plum in the diet positively influenced bone mineral density (BMD), bone strength, and bone biomarkers in men. Sixty-six men were rando ...
DOI:
10.1089/jmf.2021.0080

67. Effects of 1α-hydroxycholecalciferol on growth performance, parameters of tibia and plasma, meat quality, and type IIb sodium phosphate cotransporter gene expression of one- to twenty-one-day-old broilers

Author:
Han, J.C.; Yang, X.D.; Zhang, T.; Li, H.; Li, W.L.; Zhang, Z.Y.; Yao, J.H.
Source:
Poultry science 2009 v.88 no.2 pp. 323-329
ISSN:
0032-5791
Subject:
skeletal development; broiler chickens; transport proteins; messenger RNA; blood chemistry; breast muscle; thighs; chicken meat; tibia; nutrient utilization; gene expression; bone density; meat tenderness; phosphates; 1alpha-hydroxycholecalciferol; vitamin supplements; color; phosphorus; bone strength
Abstract:
... This experiment was conducted to investigate the effects of 1α-hydroxycholecalciferol (1α-OH D₃) on the growth performance, tibia and plasma parameters, nutrient utilization, meat quality of the breast and thigh, and type IIb sodium phosphate cotranspoter gene expression of broilers. A total of 96 males of 1-d-old Arbor Acres broilers were randomly assigned to 8 cages of 12 birds each. Two dietary ...
DOI:
10.3382/ps.2008-00252

68. Effects of Caponization and Different Exogenous Androgen on the Bone Characteristics of Male Chickens

Author:
Chen, K.L.; Tsay, S.M.; Lee, T.Y.; Chiou, P.W.S.
Source:
Poultry science 2006 v.85 no.11 pp. 1975-1979
ISSN:
0032-5791
Subject:
drug implants; body weight; tibia; bending strength; cockerels; cholesterol; bone density; testosterone; phosphorus; bone strength; castration; metabolites
Abstract:
... The effects of caponization and androgen implantation on the bone characteristics of male chickens were evaluated. Healthy Single Comb White Leghorn cockerels were caponized or sham operated (sham) at 12 wk old. Sixteen birds from each group were selected for a 14-wk experiment in trial 1. Sixteen birds from the sham group and 64 from the caponized group (randomly allocated into 4 treatments) were ...
DOI:
10.1093/ps/85.11.1975
PubMed:
17032832

69. Effects of Creatine Supplementation on Properties of Muscle, Bone, and Brain Function in Older Adults: A Narrative Review

Author:
Scott C. Forbes; Darren G. Candow; Luis H. B. Ferreira; Tacito P. Souza-Junior
Source:
Journal of dietary supplements 2022 v.19 no.3 pp. 318-335
ISSN:
1939-022X
Subject:
bone density; bone strength; brain; creatine; lifestyle; muscle tissues; muscles; nitrogen
Abstract:
... Aging is associated with reductions in muscle and bone mass and brain function, which may be counteracted by several lifestyle factors, of which exercise appears to be most beneficial. However, less than 20% of older adults (> 55 years of age) adhere to performing the recommended amount of resistance training (≥ 2 days/week) and less than 12% regularly meet the aerobic exercise guidelines (≥ 150 m ...
DOI:
10.1080/19390211.2021.1877232

70. Effects of Recombinant Human Lactoferrin on Osteoblast Growth and Bone Status in Piglets

Author:
Qiuling Li; Jie Zhao; Wenping Hu; Jianwu Wang; Tian Yu; Yunping Dai; Ning Li
Source:
Animal biotechnology 2018 v.29 no.2 pp. 90-99
ISSN:
1532-2378
Subject:
blood serum; bone density; bone formation; bone health; bone resorption; bone strength; calcium; cell differentiation; glycoproteins; humans; immunomodulators; lactoferrin; metabolites; milk; mineral content; mitogen-activated protein kinase; models; neonates; osteoblasts; phosphorylation; piglets; postmenopause; therapeutics; tibia
Abstract:
... Lactoferrin (LF), an ~80 kDa iron-binding glycoprotein, modulates many biological effects, including antimicrobial and immunomodulatory activities. Recently, it was shown that LF also regulates bone cell activity, suggesting its therapeutic effect on postmenopausal bone loss. However, a minimal amount is known regarding the effects of recombinant human LF (rhLF) supplementation on bone status in y ...
DOI:
10.1080/10495398.2017.1313269

71. Effects of Trigonelline, an Alkaloid Present in Coffee, on Diabetes-Induced Disorders in the Rat Skeletal System

Author:
Joanna Folwarczna; Aleksandra Janas; Maria Pytlik; Urszula Cegieła; Leszek Śliwiński; Zora Krivošíková; Kornélia Štefíková; Martin Gajdoš
Source:
Nutrients 2016 v.8 no.3 pp. -
ISSN:
2072-6643
Subject:
animal disease models; blood glucose; blood serum; bone density; bone fractures; bone mineralization; bone strength; diabetes; females; glycemic effect; laboratory animals; mechanical properties; nicotinamide; rats; streptozotocin; trigonelline
Abstract:
... Diabetes increases bone fracture risk. Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. The aim of the study was to investigate the effects of trigonelline on experimental diabetes-induced disorders in the rat skeletal system. Effects of trigonelline (50 mg/kg p.o. daily for four weeks) were investigated in three-month-old female Wistar ...
DOI:
10.3390/nu8030133
PubMed:
26950142
PubMed Central:
PMC4808862

72. Effects of Voluntary Resistance Exercise and High-protein Snack on Bone Mass, Composition, and Strength in Rats Given Glucocorticoid Injections

Author:
Tatsuhiro MATSUO; Tsutomu NOZAKI; Koji OKAMURA; Keitaro MATSUMOTO; Tatsuya DOI; Shoich GOHTANI; Masashige SUZUKI
Source:
Bioscience, biotechnology, and biochemistry 2003 v.67 no.12 pp. 2518-2523
ISSN:
1347-6947
Subject:
biotechnology; bone density; cages; calcium; energy; glucocorticoids; males; models; osteopenia; osteoporosis; protein content; protein intake; strength training; therapeutics; weight gain
Abstract:
... We examined the effects of a voluntary resistance exercise (climbing) together with high-protein snacks (60% protein) on bone mass and strength in rats given glucocorticoid-injections (2 mg/kg/day) as a model of age-related osteopenia. Fifty-two male Sprague-Dawley rats, 8 weeks age, were assigned to exercise or sedentary groups. These groups were further divided into groups that received no snack ...
DOI:
10.1271/bbb.67.2518

73. Effects of a Lactobacillus casei 393 fermented milk product on bone metabolism in ovariectomised rats

Author:
Kim, Jong Gun; Lee, Eungsuk; Kim, Sae Hun; Whang, Kwang Youn; Oh, Sejong; Imm, Jee-Young
Source:
International dairy journal 2009 v.19 no.11 pp. 690-695
ISSN:
0958-6946
Subject:
starter cultures; osteoclasts; bone metabolism; acid phosphatase; bone strength; ovariectomy; osteoblasts; bone density; cell proliferation; animal models; dried skim milk; Lactobacillus casei; osteoporosis; rats; fermented milk; dietary supplements; females
Abstract:
... The effects of a Lactobacillus casei 393 fermented milk product (FMP) on bone metabolism were examined. FMP (>0.1 mg mL^-^1) supplementation significantly increased osteoblastic MC3T3-E1 cells proliferation whereas skim milk powder supplementation did not show any positive effect up to 1 mg mL^-^1. The FMP (1%) supplemented ovariectomised rats had increased bone weight, bone mineral density, and b ...
DOI:
10.1016/j.idairyj.2009.06.009

74. Effects of a magnesium adhesive cement on bone stability and healing following a metatarsal osteotomy in horses

Author:
Waselau, M.; Samii, V.F.; Weisbrode, S.E.; Litsky, A.S.; Bertone, A.L.
Source:
American journal of veterinary research 2007 v.68 no.4 pp. 370-378
ISSN:
0002-9645
Subject:
horses; fracture fixation; metatarsus; adhesives; magnesium phosphates; calcium phosphates; bone formation; bone density; bone strength; tissue repair; biodegradable products; postoperative complications; bone fractures
DOI:
10.2460/ajvr.68.4.370
PubMed:
17397291

75. Effects of additional organic micro-minerals and methionine on carcass composition, gait score, bone characteristics, and osteochondrosis in replacement gilts of different growth rate

Author:
Lluís Fabà; Josep Gasa; Mike D. Tokach; Maria Font-i-Furnols; Ester Vilarrasa; David Solà-Oriol
Source:
Animal feed science and technology 2019 pp. -
ISSN:
0377-8401
Subject:
Porcine reproductive and respiratory syndrome virus; average daily gain; body weight; bone density; bone formation; bone strength; calcium; carcass composition; computed tomography; copper; feed supplements; gait; gilts; lameness; manganese; metacarpus; methionine; mineralization; nutritional intervention; osteochondrosis; sows; swine feeding; tibia; zinc
Abstract:
... Osteochondrosis (OC) is a multifactorial defective endochondral ossification that causes lameness and early culling in gilts and sows. Previous research suggested that nutrition and growth rate could influence OC development and progression. As part of a broader study [n = 360 gilts; 28.8 ± 8.8 kg body weight (BW)] designed to evaluate the effect of 4 dietary treatments: 1) basal diet (CON); 2) CO ...
DOI:
10.1016/j.anifeedsci.2019.114262

76. Effects of alfalfa and fructooligosaccharide on molting parameters and bone qualities using dual energy x-ray absorptiometry and conventional bone assays

Author:
Kim, W.K.; Donalson, L.M.; Mitchell, A.D.; Kubena, L.F.; Nisbet, D.J.; Ricke, S.C.
Source:
Poultry science 2006 v.85 no.1 pp. 15-20
ISSN:
0032-5791
Subject:
laying hens; induced molting; feed deprivation; bone density; dual-energy X-ray absorptiometry; bone strength; calcium; intestinal absorption
Abstract:
... The aim of this study was to evaluate effects of alfalfa and fructooligosaccharides (FOS) on molting performance and bone parameters compared with the conventional feed withdrawal molting procedure. A total of 36 Single Comb White Leghorn hens (84 wk of age) were used for this experiment. The hens were divided into 6 treatment groups with 6 birds per treatment: pretrial control (PC), full fed (FF) ...
Handle:
10113/3880
DOI:
10.1093/ps/85.1.15
PubMed:
16493940

77. Effects of alpha-lipoic acid on the behavior, serum indicators, and bone quality of broilers under stocking density stress

Author:
Huihui Ma; Bin Xu; Wenjia Li; Fengxian Wei; Woo Kyun Kim; Chongxiao Chen; Quanyou Sun; Chen Fu; Gaili Wang; Shaoyu Li
Source:
Poultry science 2020 v.99 no.10 pp. 4653-4661
ISSN:
0032-5791
Subject:
alkaline phosphatase; antioxidant activity; blood serum; bone density; bone strength; broiler chickens; calcium; catalase; corticosterone; dietary supplements; enzyme activity; femur; glutathione peroxidase; heterophils; ingestion; lipoic acid; males; malondialdehyde; oxidants; oxidative stress; parathyroid hormone; physiological response; preening; stocking rate; superoxide dismutase; tibia; walking
Abstract:
... The objective of present study was to investigate the effects of alpha-lipoic acid (ALA) dietary supplementation on the behavior, physiological and oxidant stress indicators, and bone quality in broilers under high stocking density (HSD) stress. A total of one thousand eight hundred 22-day-old Arbor Acres male broiler chicks were randomly allocated to 18 pens (2.97 × 2.03 m) in 3 groups: 14 birds/ ...
DOI:
10.1016/j.psj.2020.05.007

78. Effects of caponization on bone characteristics and histological structure in chickens

Author:
Chen, K.L.; Chang, M.H.; Tsay, S.M.; Hurng, H.Y.; Chiou, P.W.S.
ISSN:
1011-2367
Subject:
castration; bone density; bone metabolism; bone strength; histology; cartilage; chondrocytes; Taiwan
DOI:
10.5713/ajas.2006.245

79. Effects of dietary calcium and phosphorus levels and supplementation of 25-hydroxycholecalciferol on performance and bone properties of broiler starters

Author:
Lianhua Zhang; Tengfei He; Miao Li; Jiangxu Hu; Xiangshu Piao
Source:
Archives of animal nutrition 2019 v.73 no.6 pp. 445-456
ISSN:
1477-2817
Subject:
25-hydroxycholecalciferol; ash content; biomechanics; blood serum; bone density; broiler chickens; broiler feeding; calcium; diet; energy; femur; growth performance; hydroxyproline; males; phosphorus; tibia
Abstract:
... To investigate effects of dietary calcium (Ca) and phosphorus (P) levels and 25-hydroxycholecalciferol (25OHD₃) supplementation on performance and bone properties of broiler starters, 224 male Arbor Acre broilers were used in a 21-d trial. Broilers were allotted to one of four treatments in a 2 × 2 factorial arrangement including diets either normal or low in Ca and P, which were further supplemen ...
DOI:
10.1080/1745039X.2019.1667192

80. Effects of dietary fat levels and feeding durations on musculoskeletal health in female rats

Author:
Chwan-Li Shen; Lixia Chen; Shu Wang; Ming-Chien Chyu
Source:
Food & function 2014 v.5 no.3 pp. 598-604
ISSN:
2042-650X
Subject:
adiponectin; bone density; bone strength; dietary fat; females; high fat diet; insulin-like growth factor I; lean body mass; leptin; lipid content; low fat diet; microstructure; osteoblasts; osteoclasts; rats
Abstract:
... Objectives: This study evaluates the effects of dietary fat levels and feeding durations on body composition, bone properties, and endocrine factors in female rats. Methods: Forty-eight 3-month-old female rats were assigned into a 2 (low-fat diet vs. high-fat diet) × 2 (4-month vs. 8-month feeding duration) factorial design. The body composition, bone matrix and microstructure, and endocrine facto ...
DOI:
10.1039/c3fo60334b

81. Efficacy and stability of a novel silica supplement for improving bone development in broilers

Author:
E. J. Burton; D. V. Scholey; D. J. Belton; M. R. Bedford; C. C. Perry
Source:
British poultry science 2020 v.61 no.6 pp. 719-724
ISSN:
1466-1799
Subject:
bioavailability; blood serum; body weight; bone density; bone strength; broiler chickens; dietary supplements; dyschondroplasia; feed conversion; feed intake; mineral content; phytases; pododermatitis; silica; silicon; skeletal development; tibia; weight gain
Abstract:
... 1. The essentiality of silicon for skeletal development has been established, but the adequacy of bioavailable silicon supply in broiler diets has not been considered for 30 years, despite average daily weight gain of birds increasing by almost a third over that time. Therefore, two studies were undertaken to investigate whether modern strains of broiler chicken benefit from diet supplementation w ...
DOI:
10.1080/00071668.2020.1799328

82. Efficacy of an Escherichia coli Phytase in Broilers Fed Adequate or Reduced Phosphorus Diets and Its Effect on Carcass Characteristics

Author:
Pillai, P.B.; O'Connor-Dennie, T.; Owens, C.M.; Emmert, J.L.
Source:
Poultry science 2006 v.85 no.10 pp. 1737-1745
ISSN:
0032-5791
Subject:
broiler chickens; broiler feeding; feed additives; phytases; bacterial proteins; Escherichia coli; fungal proteins; phosphorus; nutrient deficiencies; dose response; liveweight gain; bone density; tibia; bone strength; bioavailability; chicken carcasses; meat processing
Abstract:
... Five experiments (EXP) were conducted to assess the efficacy of an Escherichia coli phytase compared with 2 commercially available fungal phytases. In EXP 1 and 2, male broiler chicks were fed experimental diets that included a P-deficient control (0.13% available P; 0.88% Ca) alone or with graded levels of KH2PO4 (0, 0.05, 0.10, or 0.15%) or phytase at levels of 250, 500, 1,000, 2,000, or 4,000 p ...
DOI:
10.1093/ps/85.10.1737
PubMed:
17012163

83. End-of-cycle bone quality in white- and brown-egg laying hens

Author:
Riczu, C.M.; Saunders-Blades, J.L.; Yngvesson, A.K.; Robinson, F.E.; Korver, D.R.
Source:
Poultry science 2004 v.83 no.3 pp. 375-383
ISSN:
0032-5791
Subject:
elderly; laying hens; egg masses; humerus; bone fractures; animal morphology; egg weight; bone density; specific gravity; laying performance; bone strength; weight; shear strength; body weight; animal welfare; strain differences; body measurements; egg shell; femur
Abstract:
... Broken and weak bones of laying hens are major welfare concerns in the table egg industry. Bone quality at the end of lay of brown- (Shaver 579) and white- (Shaver 2000) egg strains were compared. Prior to the start of the experiment, the hens had been housed in laying hen cages (2/cage). At 423 d of age (60 wk + 3 d), 24 hens of each strain were selected and individually caged, and egg production ...
DOI:
10.1093/ps/83.3.375
PubMed:
15049489

84. Endurance training has little impact on mineral content of the third metacarpus in two-year-old Arabian horses

Author:
Spooner, H.S.; Nielsen, B.D.; Woodward, A.D.; Rosenstein, D.S.; Harris, P.A.
Source:
Journal of equine veterinary science 2008 v.28 no.6 pp. 359-362
ISSN:
0737-0806
Subject:
racehorses; bone mineralization; bone strength; training (animals); strength training; Arabian (horse breed); young animals; metacarpus; mineral content; bone density; exercise test; absorbance; radiography

85. Energy-restricted diet benefits body composition but degrades bone integrity in middle-aged obese female rats

Author:
Chwan-Li Shen; Wenbin Zhu; Weimin Gao; Shu Wang; Lixia Chen; Ming-Chien Chyu
Source:
Nutrition research 2013 v.33 no.8 pp. 668-676
ISSN:
0271-5317
Subject:
adiponectin; body composition; body weight; bone density; bone formation; bone resorption; bone strength; gene expression; glutathione peroxidase; high fat diet; insulin-like growth factor I; leptin; low calorie diet; low fat diet; mechanical properties; protein synthesis; rats; tumor necrosis factors
Abstract:
... This study investigates the effects of a restricted diet (RD) on body composition and musculoskeletal health along with endocrines and molecular mechanism in established mature obese rats. Twenty female rats were fed with a high-fat diet (HFD) ad libitum for 4 months and then assigned to either HFD or RD group for another 4 months. Another 10 rats were on a low-fat diet for 8 months. Outcome measu ...
DOI:
10.1016/j.nutres.2013.05.008
PubMed:
23890357

86. Estimation of bone mineral density and breaking strength of laying hens based on scans of computed tomography for body composition analysis

Author:
T. Donkó; A. Tischler; Á. Csóka; G. Kovács; M. Emri; Ö. Petneházy; A. Szabó; V. Halas; J. Tossenberger; R. Garamvölgyi; G. Bajzik
Source:
British poultry science 2018 v.59 no.4 pp. 365-370
ISSN:
1466-1799
Subject:
ash content; body composition; bone density; computed tomography; data collection; egg production; genotype; laying hens; prediction
Abstract:
... 1. The objective of this study was to evaluate the prediction potential of a computer tomography (CT) data collection protocol for determining total body composition used for analysis of tibiotarsal bone quality features. 2. The CT image acquisition was performed on 54 healthy TETRA SL genotype laying hens at 90 weeks of age as well as in the 69th week of the egg production period in vivo and thei ...
DOI:
10.1080/00071668.2018.1471662

87. Estrogen receptor-α expression in neuronal cells affects bone mass

Author:
Claes Ohlsson; Cecilia Engdahl; Anna E. Börjesson; Sara H. Windahl; Erik Studer; Lars Westberg; Elias Eriksson; Antti Koskela; Juha Tuukkanen; Andree Krust; Pierre Chambon; Hans Carlsten; Marie K. Lagerquist
Source:
Proceedings of the National Academy of Sciences of the United States of America 2012 v.109 no.3 pp. 983-988
ISSN:
0027-8424
Subject:
bone density; bone formation; bone strength; femur; homeostasis; hypothalamus; leptin; messenger RNA; mice; phenotype; secretion; white adipose tissue
Abstract:
... It has generally been assumed that bone mass is controlled by endocrine mechanisms and the local bone environment. Recent findings demonstrate that central pathways are involved in the regulation of bone mass. Estrogen is involved in the regulation of bone homeostasis and the CNS is also a target for estrogen actions. The aim of this study was to investigate in vivo the role of central estrogen re ...
DOI:
10.1073/pnas.1111436109
PubMed:
22215598
PubMed Central:
PMC3271867

88. Evaluation of phytase concentration needed for growing-finishing commercial turkey toms

Author:
Roberson, K.D.; Klunzinger, M.W.; Charbeneau, R.A.; Orth, M.W.
Source:
British poultry science 2005 v.46 no.4 pp. 470-477
ISSN:
0007-1668
Subject:
osteocalcin; phytases; blood chemistry; food animals; body weight; feed conversion; turkey feeding; poultry manure; toms; liveweight gain; bone density; finishing; phosphorus; feed supplements; bone strength
Abstract:
... 1. Growth performance, serum bone markers, and bone strength and mineralisation were determined in tom turkeys grown from 9 to 17 weeks of age. 2. Dietary non-phytate phosphorus was formulated to be reduced by 1.0 g/kg in the low phosphorus diet compared to a control diet and phytase was added to provide 0, 150, 300, 450 or 600 units/kg activity to the low phosphorus diet. 3. From 9 to 12 weeks of ...
DOI:
10.1080/00071660500190769
PubMed:
16268105

89. Evaluation of serum concentrations of biochemical markers of bone metabolism and insulin-like growth factor I associated with treadmill exercise in young horses

Author:
Jackson, Brendan F.; Goodship, Allen E.; Eastell, Richard; Price, Joanna S.
Source:
American journal of veterinary research 2003 v.64 no.12 pp. 1549-1556
ISSN:
0002-9645
Subject:
Thoroughbred; alkaline phosphatase; biomarkers; blood serum; bone density; bone formation; bone resorption; bone strength; collagen; dual-energy X-ray absorptiometry; exercise; insulin-like growth factor I; mares; osteocalcin; walking
Abstract:
... Objective-To evaluate changes in serum concentrations of biochemical markers of bone metabolism and insulin-like growth factor I (IGF-I) associated with treadmill exercise in young horses. Animals-12 two-year-old Thoroughbred mares. Procedure-During a 20-week study period, 6 horses were exercised on a treadmill 3 times a week (exercise group) and 6 horses received walking exercise 6 days a week (c ...
DOI:
10.2460/ajvr.2003.64.1549

90. Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in healthy equine joints with different functional demands

Author:
Lewis, C.W.; Williamson, A.K.; Chen, A.C.; Bae, W.C.; Temple, M.M.; Wong, V.W.; Nugent, G.E.; James, S.P.; Wheeler, D.L.; Sah, R.L.
Source:
American journal of veterinary research 2005 v.66 no.10 pp. 1823-1829
ISSN:
0002-9645
Subject:
dual-energy X-ray absorptiometry; horses; tensile strength; cartilage; bone density; spatial variation; joints (animal); bone strength
DOI:
10.2460/ajvr.2005.66.1823
PubMed:
16273917

91. Evaluation of the effect of CaD on the bone structure and bone metabolic changes in senile osteoporosis rats based on MLP–ANN methods

Author:
Xiufeng Tang; Yingying Gao; Yuheng Chen; Xiaoxi Li; Ping Yu; Zitong Ma; Renhui Liu
Source:
Food & function 2019 v.10 no.12 pp. 8026-8041
ISSN:
2042-650X
Subject:
Western blotting; acid phosphatase; alkaline phosphatase; biomechanics; blood serum; bone density; bone metabolism; bone strength; calcium; cholecalciferol; drugs; fluorescent antibody technique; insulin-like growth factor I; laboratory animals; macrophage colony-stimulating factor; males; messenger RNA; micro-computed tomography; microstructure; models; osteoporosis; pathogenesis; protein synthesis; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; tibia; transforming growth factor beta 1
Abstract:
... Senile osteoporosis (SOP) is a related disease of systematic degenerative changes in bones during natural aging. Increasing age is an important factor in its pathogenesis. This experiment was to evaluate the comprehensive effect of calcium with vitamin D3 (CaD) on SOP based on multilayer perception (MLP)–artificial neural network (ANN) methods. 15-month-old male Sprague-Dawley rats were administer ...
DOI:
10.1039/c9fo01322a

92. Experimental osteoporosis in sheep – mechanical and histological approach

Author:
Z. Kiełbowicz; A. Piątek; P. Kuropka; E. Mytnik; A. Nikodem; J. Bieżyński; P. Skrzypczak; C. Pezowicz; J. Kuryszko; P. Reichert
Source:
Polish journal of veterinary sciences 2016 v.19 no.1 pp. 109-118
ISSN:
2300-2557
Subject:
animal models; bone density; bone strength; cartilage; females; histology; methylprednisolone; mineral content; osteoporosis; sheep; therapeutics
Abstract:
... The implementation of new methods of osteoporotic therapy requires tests on animal model. The use of sheep as model has numerous advantages over other animals. The aim of this study was to describe the change in parameters in sheep with osteoporosis induced using steroids and ovariorectomy methods as opposed to the parameters in healthy sheep. The study was performed on female „merinos” breed shee ...
DOI:
10.1515/pjvs-2016-0014

93. Exposure to pastures fertilised with sewage sludge disrupts bone tissue homeostasis in sheep

Author:
Lind, P. Monica; Gustafsson, Magnus; Hermsen, Sanne A.B.; Larsson, Sune; Kyle, Carol E.; Örberg, Jan; Rhind, Stewart M.
Source:
Science of the total environment 2009 v.407 no.7 pp. 2200-2208
ISSN:
0048-9697
Subject:
sheep; femur; homeostasis; bone strength; bone density; biomarkers; computed tomography; environmental exposure; pastures; organic fertilizers; sewage sludge; pollutants; ecotoxicology; Scotland
Abstract:
... The femurs of male and female sheep (Ovis aries), aged 18 months, bred on pastures fertilized twice annually with sewage sludge (2.25 tonnes dry matter/ha; Treated; T)) or on pastures treated with inorganic fertilizer (Control; C) were studied, using peripheral Quantitative Computed Tomography (pQCT) and the three-point bending test. Males were maintained on the respective treatments from concepti ...
DOI:
10.1016/j.scitotenv.2008.12.035
PubMed:
19162300

94. Fat, Sugar, and Bone Health: A Complex Relationship

Author:
Li Tian; Xijie Yu
Source:
Nutrients 2017 v.9 no.5 pp. -
ISSN:
2072-6643
Subject:
bone density; bone health; bone marrow; bone metabolism; bone strength; chronic diseases; coronary disease; diabetes; fructose; glucose; grains; high fat diet; high fructose diet; lipid metabolism; microstructure; nutrient content; nutrients; nutritional status; obesity; osteoporosis; proteins; risk factors; saturated fats; starch; sucrose; China
Abstract:
... With people aging, osteoporosis is expected to increase notably. Nutritional status is a relatively easily-modified risk factor, associated with many chronic diseases, and is involved in obesity, diabetes, and coronary heart disease (CHD), along with osteoporosis. Nutrients, such as fats, sugars, and proteins, play a primary function in bone metabolism and maintaining bone health. In Western natio ...
DOI:
10.3390/nu9050506
PubMed:
28513571
PubMed Central:
PMC5452236

95. Feeding Orange Pulp Improved Bone Quality in a Rat Model of Male Osteoporosis

Author:
Morrow, Rori; Deyhim, Farzad; Patil, Bhimanagouda S.; Stoecker, Barbara J.
Source:
Journal of medicinal food 2009 v.12 no.2 pp. 298-303
ISSN:
1096-620X
Subject:
citrus pulp; oranges; functional foods; osteoporosis; rats; animal models; males; oxidative stress; inflammation; ascorbic acid; flavonoids; bone density; feed intake; computed tomography; bone strength; tibia; urine; volume; bone resorption; microstructure; testosterone
DOI:
10.1089/jmf.2008.0145
PubMed:
19459729

96. Fluoride exposure and bone status in patients with chronic intestinal failure who are receiving home parenteral nutrition

Author:
Boulétreau, Paul H.; Bost, Muriel; Fontanges, Elisabeth; Lauverjat, Madeleine; Gutknecht, Christel; Ecochard, René; Delmas, Pierre D.; Chambrier, Cécile
Source:
American journal of clinical nutrition 2006 v.83 no.6 pp. 1429-1437
ISSN:
0002-9165
Subject:
adults; patients; parenteral feeding; fluorides; dietary exposure; developmental orthopedic disease; digestive system diseases; bone density; bone strength; blood chemistry; food intake; regression analysis; fluorosis; signs and symptoms (animals and humans); feces
Abstract:
... BACKGROUND: and Objective: Metabolic bone disease is frequent in chronic intestinal failure. Because fluoride has a major effect on bones, the status of both fluoride and bone was studied in long-term home parenteral nutrition (HPN) patients. DESIGN: We studied 31 adults aged (x ± SD) 56.3 ± 15.1 y, mainly patients with short-bowel syndrome, who had been receiving HPN for >1 y. Bone mineral densit ...
PubMed:
16762955

97. Fruit and vegetable intakes and bone mineral status: a cross-sectional study in 5 age and sex cohorts

Author:
Prynne, Celia J.; Mishra, Gita D.; O'Connell, Maria A.; Muniz, Graciela; Laskey, M. Ann; Yan, Liya; Prentice, Ann; Ginty, Fiona
Source:
American journal of clinical nutrition 2006 v.83 no.6 pp. 1420-1428
ISSN:
0002-9165
Subject:
nutrient intake; food intake; elderly; men; women; physical activity; gender differences; age; bone density; adolescents; food choices; vegetables; lifestyle; bone strength
Abstract:
... BACKGROUND: Evidence is increasing for positive effects of fruit and vegetable intakes on bone health. However, most of the studies to date were conducted in adults, and few reports included adolescents. OBJECTIVE: We explored the association between bone mineral status and fruit and vegetable intakes in adolescent boys and girls (aged 16-18 y), young women (aged 23-37 y), and older men and women ...
PubMed:
16789345

98. Fruit and vegetables: the unexpected natural answer to the question of osteoporosis prevention

Author:
Lanham-New, Susan A.
Source:
American journal of clinical nutrition 2006 v.83 no.6 pp. 1254-1255
ISSN:
0002-9165
Subject:
diet-related diseases; food intake; elderly; humans; biomarkers; disease prevention; bone density; osteoporosis; food choices; vegetables; bone strength
PubMed:
16762933

99. Fruits and dietary phytochemicals in bone protection

Author:
Chwan-Li Shen; Vera von Bergen; Ming-Chien Chyu; Marjorie R. Jenkins; Huanbiao Mo; Chung-Hwan Chen; In-Sook Kwun
Source:
Nutrition research 2012 v.32 no.12 pp. 897-910
ISSN:
0271-5317
Subject:
prunes; apples; grapes; bone density; metabolites; tomatoes; risk; animals; lycopene; bone strength; microstructure; mineralization; pectins; bone formation; phloridzin; osteoporosis; resveratrol; cross-sectional studies; bone resorption; antioxidants; citrus fruits; fruits; fruit consumption
Abstract:
... Osteoporosis is a disease of bone characterized by loss of bone matrix and deterioration of bone microstructure that leads to an increased risk of fracture. Cross-sectional studies have shown a positive association between higher fruit intake and higher bone mineral density. In this review, we evaluated animal and cellular studies of dried plum and citrus and berry fruits and bioactive compounds i ...
DOI:
10.1016/j.nutres.2012.09.018
PubMed:
23244535

100. Gait parameters in four strains of turkeys and correlations with bone strength

Author:
E.O. Oviedo-Rondón; B.D.X. Lascelles; C. Arellano; P.L. Mente; P. Eusebio-Balcazar; J.L. Grimes; A.D. Mitchell
Source:
Poultry science 2017 v.96 no.7 pp. 1989-2005
ISSN:
0032-5791
Subject:
biomechanics; bone density; bone strength; etiology; femur; gait; locomotion; meat; tibia; toms
Abstract:
... Locomotion problems in meat poultry have multifactorial etiology. A better understanding of normal gait and its influences on biomechanical aspects of leg bones among turkey genetic lines is important to prevent skeletal disorders and locomotion issues. The objective of this experiment was to determine the possible differences in gait kinetic and kinematic parameters of turkey strains and their ef ...
DOI:
10.3382/ps/pew502