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- Uesugi, Sandra L., et al. Show all 15 Authors
- Food and chemical toxicology 2018 v.115 pp. 136-147
- United States Environmental Protection Agency; absorption; adults; benzo(a)pyrene; carbon; carcinogenicity; carcinogens; dietary exposure; dietary restriction; food matrix; humans; mass spectrometry; models; neoplasms; pharmacokinetics; polycyclic aromatic hydrocarbons; questionnaires; radionuclides; salmon; smoked salmon; toxicology
- ... Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), is a known human carcinogen. In non-smoking adults greater than 95% of BaP exposure is through diet. The carcinogenicity of BaP is utilized by the U.S. EPA to assess relative potency of complex PAH mixtures. PAH relative potency factors (RPFs, BaP = 1) are determined from high dose animal data. We employed accelerator mass spectrometry ...