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You searched for: Author "Nakayasu, Chihaya" Remove constraint Author: "Nakayasu, Chihaya" Subject cell-mediated immunity Remove constraint Subject: cell-mediated immunity
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1. Adaptive immune response to Edwardsiella tarda infection in ginbuna crucian carp, Carassius auratus langsdorfii

Author:
Nakayasu, Chihaya,   et al.   ; Yamasaki, Masatoshi; Araki, Kyosuke; Nakanishi, Teruyuki; Yoshiura, Yasutoshi; Iida, Takaji; Yamamoto, Atsushi;     Show all 7 Authors
Source:
Veterinary immunology and immunopathology 2013 v.153 no.1-2 pp. 83-90
ISSN:
0165-2427
Subject:
Carassius auratus; Carassius carassius; Edwardsiella tarda; antibacterial properties; antibodies; bacteria; bacterial infections; cell-mediated immunity; cytotoxic T-lymphocytes; cytotoxicity; fish; humoral immunity; immune response; kidneys; mammals; pathogens; spleen
Abstract:
... Edwardsiella tarda is an intracellular pathogen that causes edwardsiellosis in fish. Although cell-mediated immunity and innate immunity play a major role in protection against intracellular bacterial infection in mammals, their importance in protecting fish against E. tarda infection remain unclear. In this study, we examined cell-mediated and humoral immune responses in ginbuna crucian carp (Car ...
DOI:
10.1016/j.vetimm.2013.02.004
PubMed:
23489657

2. Comparative analysis of adaptive immune response after vaccine trials using live attenuated and formalin-killed cells of Edwardsiella tarda in ginbuna crucian carp (Carassius auratus langsdorfii)

Author:
Nakayasu, Chihaya,   et al.   ; Yamasaki, Masatoshi; Araki, Kyosuke; Maruyoshi, Kota; Matsumoto, Megumi; Moritomo, Tadaaki; Nakanishi, Teruyuki; Yamamoto, Atsushi;     Show all 8 Authors
Source:
Fish & shellfish immunology 2015 v.45 no.2 pp. 437-442
ISSN:
1050-4648
Subject:
Carassius auratus; Edwardsiella tarda; antibodies; cell-mediated immunity; cytotoxic T-lymphocytes; fish; gene expression; interleukin-10; live vaccines; pathogens; survival rate; vaccination; vaccine development
Abstract:
... Edwardsiella tarda is an intracellular pathogen that causes edwardsiellosis in fish. Although vaccine trials with formalin-killed cells (FKC) have been reported, the vaccinations failed in protect against E. tarda infection. On the other hand, a live attenuated vaccine strategy is effective against edwardsiellosis; however, the mechanism underlying its effectiveness in fish is unclear. In the pres ...
DOI:
10.1016/j.fsi.2015.04.038

3. Role of CD4+ and CD8α+ T cells in protective immunity against Edwardsiella tarda infection of ginbuna crucian carp, Carassius auratus langsdorfii

Author:
Nakayasu, Chihaya,   et al.   ; Yamasaki, Masatoshi; Araki, Kyosuke; Nakanishi, Teruyuki; Yamamoto, Atsushi;     Show all 5 Authors
Source:
Fish & shellfish immunology 2014 v.36 no.1 pp. 299-304
ISSN:
1050-4648
Subject:
CD4-positive T-lymphocytes; Carassius auratus; Edwardsiella tarda; cell-mediated immunity; cytotoxic T-lymphocytes; cytotoxicity; fish; gene expression; gene expression regulation; interferon-gamma; pathogens; protective effect
Abstract:
... Edwardsiella tarda is an intracellular pathogen that causes edwardsiellosis in fish. Our previous study suggests that cell-mediated immunity (CMI) plays an essential role in protection against E. tarda infection. In the present study, we adoptively transferred T-cell subsets sensitized with E. tarda to isogenic naïve ginbuna crucian carp to determination the T-cell subsets involved in protecting f ...
DOI:
10.1016/j.fsi.2013.11.016