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You searched for: Subject term cerebrospinal fluid Remove constraint Subject term: cerebrospinal fluid Subject term biotin Remove constraint Subject term: biotin Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers

Author:
Jo V. Rushworth; Asif Ahmed; Heledd H. Griffiths; Niall M. Pollock; Nigel M. Hooper; Paul A. Millner
Source:
Biosensors & bioelectronics 2014 v.56 pp. 83-90
ISSN:
0956-5663
Subject:
Alzheimer disease; biomarkers; biosensors; biotin; blood; brain; cerebrospinal fluid; commercialization; dielectric spectroscopy; disease surveillance; early diagnosis; electrodes; gold; neurons; neurotoxicity; prions; scanning electron microscopy
Abstract:
... Alzheimer's disease (AD) is the most common form of dementia, with over 37 million sufferers worldwide and a global cost of over $600 billion. There is currently no cure for AD and no reliable method of diagnosis other than post-mortem brain examination. The development of a point-of-care test for AD is an urgent requirement in order to provide earlier diagnosis and, thus, useful therapeutic inter ...
DOI:
10.1016/j.bios.2013.12.036

2. Amplified voltammetric detection of dopamine using ferrocene-capped gold nanoparticle/streptavidin conjugates

Author:
Lin Liu; Jimin Du; Sujuan Li; Baiqing Yuan; Hongxing Han; Min Jing; Ning Xia
Source:
Biosensors & bioelectronics 2013 v.41 pp. 730-735
ISSN:
0956-5663
Subject:
biosensors; biotin; brain; cerebrospinal fluid; detection limit; dopamine; electrochemistry; electrodes; gold; mammals; nanogold; neurotransmitters; streptavidin; tissues
Abstract:
... Dopamine (DA) is one of the most important neurotransmitters present in brain tissues and body fluids of mammals. The change in the concentration levels has been associated with various diseases and disorders. Thus, sensitive and selective determination of DA is much preferred. In this work, sandwich-type electrochemical biosensor was developed, in which phenylboronic acid immobilized onto gold el ...
DOI:
10.1016/j.bios.2012.09.061

3. CD8 T cell-derived perforin aggravates secondary spinal cord injury through destroying the blood-spinal cord barrier

Author:
Zhaoxiang Liu; Hua Zhang; Hong Xia; Baocheng Wang; Renwen Zhang; Qun Zeng; Lingzhi Guo; Kui Shen; BaTa Wang; Yanheng Zhong; Zhizhong Li; Guodong Sun
Source:
Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
ISSN:
0006-291X
Subject:
CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
Abstract:
... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
DOI:
10.1016/j.bbrc.2019.03.002