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1. 1H NMR and HPLC-DAD-MS for the characterization of ellagitannins and triterpenoids of less investigated Anogeissus leiocarpus DC (Combretaceae) stem bark

Author:
Titilayo Akande; Mohamad Khatib; Sule Ola Salawu; Akintunde Afolabi Akindahunsi; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Diletta Balli; Lorenzo Cecchi; Nadia Mulinacci
Source:
Food chemistry 2022 v.375 pp. 131813
ISSN:
0308-8146
Subject:
Anogeissus; bark; chemical constituents of plants; dietary supplements; food chemistry; glycosylation; osteoarthritis; phytochemicals; traditional medicine; trees; triterpenoids; Africa; Asia
Abstract:
... Anogeissus leiocarpus DC is an evergreen tree, widely distributed in Asia and Africa. The stem bark is used in traditional medicine, and as chewing sticks and infusion. Nowadays, it is becoming increasingly important to define the phytochemical profile of less studied edible plants. Aim of this research was a first complete characterization of ellagitannins and triterpenoids profiles by HPLC-DAD-M ...
DOI:
10.1016/j.foodchem.2021.131813

2. A Review of the Anti-Cancer Potential of Murraya koenigii (Curry Tree) and Its Active Constituents

Author:
Aniqa Aniqa; Sarvnarinder Kaur; Shilpa Sadwal
Source:
Nutrition and cancer 2022 v.74 no.1 pp. 12-26
ISSN:
1532-7914
Subject:
Bergera koenigii; animals; apoptosis; breasts; cell cycle; chemical constituents of plants; colon; liver; lungs; nutrition; surveys; terpenoids
Abstract:
... Murraya koenigii (MK) relates to the Rutaceae family and has many health benefits. To date, over eighty-eight carbazole alkaloids along with terpenoids, and other nutrients have been identified from different parts of this plant. This review presents accumulated information regarding the role of MK and its constituents in the prevention/treatment of cancer. Literature survey revealed that MK and i ...
DOI:
10.1080/01635581.2021.1882509

3. A chalcone (Pongamol) and phytoconstituents of Tephrosia purpurea

Author:
Kitherian Sahayaraj; Poolpandi Kombiah; Jesu Antony Martin Rathi
Source:
Natural product research 2022 v.36 no.7 pp. 1870-1873
ISSN:
1478-6427
Subject:
Tephrosia purpurea; chalcone; chemical constituents of plants; chromatography; cyclohexanes; quantitative analysis; research; saponins; secondary metabolites; stem extracts
Abstract:
... Tephrosia purpurea stem extract fractions shows more amount of Cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1α,2β,4β)- (62.32%). Secondary metabolites contents were higher in stem than root of T. purpurea. It is the first time a chalcone (Pongamol) was crystallised from the column chromatography fraction of T. purpurea stem extract identified by using FT-IR and XRD. Quantitative ana ...
DOI:
10.1080/14786419.2020.1808640

4. A comprehensive review on ethnobotany, nutritional values, phytochemistry and pharmacological attributes of ten potent Garcinia species of South-east Asia

Author:
Arpita Paul; Md. Kamaruz Zaman
Source:
South African journal of botany 2022 v.148 pp. 39-59
ISSN:
0254-6299
Subject:
Garcinia; adverse effects; antioxidants; benzophenones; biomedical research; chemical constituents of plants; drugs; ethnobotany; flavonoids; mechanism of action; terpenoids; toxicology; traditional medicine; xanthones; South East Asia
Abstract:
... The tropical plants of Garcinia (Clusiaceae family) have been extensively used in folk medicine apart from its limited use in the preparation of certain dishes. This paper aims to provide a comprehensive and updated report on the diverse range of phytochemicals, the traditional uses, the nutritional values, the major pharmacological attributes, and the toxicological findings of ten Garcinia plants ...
DOI:
10.1016/j.sajb.2022.03.032

5. A critical review on phytopharmacology, spectral and computational analysis of phytoconstituents from Streblus asper Lour

Author:
Rinkal Chamariya; Radhika Raheja; Vasanti Suvarna; Richie Bhandare
Source:
Phytomedicine plus 2022 v.2 no.1 pp. 100177
ISSN:
2667-0313
Subject:
Streblus asper; analgesics; botanical gardens; chemical constituents of plants; cytotoxicity; databases; dental caries; dysentery; humans; hypoglycemia; leprosy; medicine; ornamental value; therapeutics; trees; viruses
Abstract:
... Phytomedicine has been practiced since time immemorial for alleviating human diseases. However, since plants offer unique phytoconstituents with specific biological activities, a systematic approach towards the use of phytomedicine is gaining immense importance since the past few decades. Family Moraceae comprises trees, shrubs, herbs, and lianas. This family includes not only fruit-bearing trees ...
DOI:
10.1016/j.phyplu.2021.100177

6. A molecular insight of inflammatory cascades in rheumatoid arthritis and anti-arthritic potential of phytoconstituents

Author:
Vaibhav Patidar; Shruti Shah; Rahul Kumar; Pankaj Kumar Singh; Shashi Bala Singh; Dharmendra Kumar Khatri
Source:
Molecular biology reports 2022 v.49 no.3 pp. 2375-2391
ISSN:
0301-4851
Subject:
T-lymphocytes; apoptosis; aryl hydrocarbon receptors; cartilage; cell differentiation; chemical constituents of plants; fibroblasts; hyperplasia; molecular biology; nucleoproteins; osteoclasts; phytochemicals; rheumatoid arthritis
Abstract:
... Rheumatoid arthritis (RA) is an auto-immune inflammatory disorder of the synovial lining of joints marked by immune cells infiltration and hyperplasia of synovial fibroblasts which results in articular cartilage destruction and bone erosion. The current review will provide comprehensive information and results obtained from the recent research on the phytochemicals which were found to have potenti ...
DOI:
10.1007/s11033-021-06986-7

7. A new cycloartane triterpene and other phytoconstituents from the aerial parts of Euphorbia dendroides

Author:
Ahmed R. Hassan; Ahmed Ashour; Yhiya Amen; Maki Nagata; Sayed A. El-Toumy; Kuniyoshi Shimizu
Source:
Natural product research 2022 v.36 no.3 pp. 828-836
ISSN:
1478-6427
Subject:
Euphorbia; chemical constituents of plants; cytotoxicity; human cell lines; research; triterpenoids
Abstract:
... New cycloartane-type triterpene 23 R/S-3β-hydroxycycloart-24-ene-23-methyl ether 1a,b (as an C-23 epimeric mixture), along with ten known compounds, including 1 steroid, 3 fatty acids and 6 triterpenoids were isolated from the aerial parts of Euphorbia dendroides L. (Euphorbiaceae). The known compounds (2–11) were identified using 1 D & 2 D-NMR spectra and by comparison with data reported in the l ...
DOI:
10.1080/14786419.2020.1800693

8. A review of some common African spices with antihypertensive potential

Author:
Raphael I. Adeoye; Enoch B. Joel; Adedoyin Igunnu; Rotimi O. Arise; Sylvia O. Malomo
Source:
Journal of food biochemistry 2022 v.46 no.1 pp. e14003
ISSN:
0145-8884
Subject:
Xylopia aethiopica; anthraquinones; blood pressure; cardiac glycosides; chemical constituents of plants; dietary supplements; drug therapy; elderly; flavonoids; heart; histology; hypertension; lifestyle; obesity; pathogenesis; polyphenols; saponins; simvastatin; toxicology; Africa
Abstract:
... Hypertension is the most common non‐communicable disease, with about 1.28 billion hypertensive people worldwide. It is more prevalent in men than women and more common in the elderly. Hereditary, age, obesity, lifestyle, diet, alcohol, and chronic metabolic diseases are the major risk factors of hypertension. Treating hypertension is a complex process as there are several mechanisms responsible fo ...
DOI:
10.1111/jfbc.14003

9. A review of the ethnomedicinal uses, chemistry, and pharmacological properties of the genus Acanthus (Acanthaceae)

Author:
Patrícia Matos; Maria Teresa Batista; Artur Figueirinha
Source:
Journal of ethnopharmacology 2022 v.293 pp. 115271
ISSN:
0378-8741
Subject:
animals; antimicrobial properties; antioxidants; chemical constituents of plants; chemistry; flavonoids; gastrointestinal system; geographical distribution; glycosides; lignans; reproductive system; therapeutics; toxicity; traditional medicine; triterpenoids; urinary tract
Abstract:
... The Acanthus genus belongs to the Acanthaceae family, and its species are distributed in all continents, mainly in tropical and subtropical regions. Several traditional applications are referred to, but few scientific studies validate them. Despite this, studies in animal models corroborate some of its uses in folk medicine, such as anticancer, antidiabetic, anti-inflammatory, and antinociceptive, ...
DOI:
10.1016/j.jep.2022.115271

10. A review on phytochemical, pharmacological attributes and therapeutic uses of Allium hookeri

Author:
Barsha Deka; Prasenjit Manna; Jagat Chandra Borah; Narayan Chandra Talukdar
Source:
Phytomedicine plus 2022 v.2 no.2 pp. 100262
ISSN:
2667-0313
Subject:
Allium hookeri; anti-inflammatory activity; body weight; broiler chickens; catechin; chemical constituents of plants; clinical trials; esophageal diseases; essential oils; ferulic acid; functional foods; linoleic acid; necrotic enteritis; people; sinapic acid; solvents; therapeutics; India
Abstract:
... : Allium hookeri is a wild perennial herb within the genus Allium and having immense beneficial medicinal properties including anti-diabetic, anti-fungal, anti-ulcer, anti-obesity, hepatoprotective, neuroprotective, hypolipidemic, anti-inflammatory activity reported in various in vitro and in vivo experimental animals including clinical trial. It is also reported to induce reflux esophagitis and p ...
DOI:
10.1016/j.phyplu.2022.100262

11. A simple validated HPTLC method for the analysis of flavonoids and molecular docking studies of novel tri-terpenoid glycoside isolated from Carya illinoinensis bark with potential anti-inflammatory and antinociceptive activities

Author:
Md.Sarfaraj Hussain; Faizul Azam; Jamal Mezogi; Fatima Abdmalla Enwij; Ghazalla M Benhusein; Anzarul Haque; Mohammad Khalid; Muhammed Arif; Mohammad Mahtab Alam; Irfan Ahmad; Mohd. Saeed
Source:
South African journal of botany 2022 v.147 pp. 596-607
ISSN:
0254-6299
Subject:
Carya illinoinensis; absorption; acetic acid; antioxidants; bark; chemical constituents of plants; flavonoids; glycosides; indomethacin; inducible nitric oxide synthase; methanol; necrosis; neoplasms; spectral analysis; terpenoids; thin layer chromatography; traditional medicine
Abstract:
... Carya illinoinensis (Family Juglandaceae) is frequently used in traditional medicine for its antimicrobial, antioxidant, anti-rheumatic, anti-diabetic, and diuretic activities. Column chromatography was used to separate phytoconstituents from an ethanolic extract of powered bark. The terpenoid glycosidic compound, CI-01, was isolated as light-yellow crystalline powder in 0.33% (w/w) yield having m ...
DOI:
10.1016/j.sajb.2022.02.016

12. Accumulation of delphinidin derivatives and other bioactive compound in wild maqui under different environmental conditions and fruit ripening stages

Author:
Antonio A. Pinto; Verónica Fuentealba-Sandoval; Maria Dolores López; Karen Peña-Rojas; Susana Fischer
Source:
Industrial crops and products 2022 pp. 115064
ISSN:
0926-6690
Subject:
Aristotelia chilensis; abiotic stress; anthocyanins; antioxidant activity; bioactive compounds; biosynthesis; chemical constituents of plants; delphinidin; flavonols; fruits; gallic acid; polyphenols; raw materials; Chile
Abstract:
... There is a growing interest in food and bioactive compounds with health benefits. Several studies on wild fruits have reported high anthocyanin contents and antioxidant potential mainly influenced by abiotic stress, particularly in native berries. Maqui (Aristotelia chilensis (Mol.) Stuntz), a Chilean native berry, has been referred as a “superfruit” due to its phytochemical composition and antiox ...
DOI:
10.1016/j.indcrop.2022.115064

13. Advances in chemistry and bioactivity of the genus Erythroxylum

Author:
Yulian Lv; Tian Tian; Yong-Jiang Wang; Jian-Ping Huang; Sheng-Xiong Huang
Source:
Natural products and bioprospecting 2022 v.12 no.1 pp. 15
ISSN:
2192-2195
Subject:
bioactive properties; central nervous system; chemical constituents of plants; cocaine; diterpenoids; flavonoids; humans; triterpenoids; India; South America
Abstract:
... Erythroxylum P. Browne is the largest and most representative genus of Erythroxylaceae family. It contains approximately 230 species that are mainly distributed in tropical and subtropical regions. Some species in this genus, such as E. monogynum and E. coca, have been used as folk medicines in India or South America for a long history. It is well known that Erythroxylum plants are rich in tropane ...
DOI:
10.1007/s13659-022-00338-z

14. Altitudinal and geographical variations in phytochemical composition and biological activities of Curcuma longa accession from Uttarakhand, the Himalayan region

Author:
Shriya Gururani; Kanchan Gairola; Ravendra Kumar; Om Prakash; Shiv Kumar Dubey
Source:
Journal of food processing and preservation 2022 v.46 no.3 pp. e16384
ISSN:
0145-8892
Subject:
Curcuma longa; altitude; anti-inflammatory activity; antioxidants; chemical composition; chemical constituents of plants; cineole; cultivars; drug therapy; essential oils; glycemic effect; habitats; hydrodistillation; pharmacodynamics; pharmacokinetics; rhizomes; turmeric; Himalayan region; India
Abstract:
... The aim of the present study was to assess the variations in chemical composition and biological activities of essential oil of Curcuma longa rhizome local cultivars collected from four varied altitudes and habitats of Kumaun and Garhwal regions of Uttarakhand, India. The essential oil was collected from the rhizomes by hydrodistillation extraction using the Clevenger apparatus. Yields of essentia ...
DOI:
10.1111/jfpp.16384

15. An Overview of Hepatocellular Carcinoma with Emphasis on Dietary Products and Herbal Remedies

Author:
Deepa S. Mandlik; Satish K. Mandlik
Source:
Nutrition and cancer 2022 v.74 no.5 pp. 1549-1567
ISSN:
1532-7914
Subject:
Food and Drug Administration; cancer therapy; chemical constituents of plants; drugs; etiology; hepatoma; nutrition; toxicity
Abstract:
... The most common principal malignant tumor that accounts for ∼80% of cases of liver cancer across the world is hepatocellular carcinoma (HCC). It is a multifacetedillness that is caused by several risk factors and often progresses in the context of underlying cirrhosis. It is tremendously difficult and essential for the screening of novel therapeutic medications to establish HCC preclinical models ...
DOI:
10.1080/01635581.2021.1965630

16. An advance on nutritional profile, phytochemical profile, nutraceutical properties, and potential industrial applications of lemon peels: A comprehensive review

Author:
Haitao Jiang; Wanli Zhang; Yan Xu; Luyao Chen; Jiankang Cao; Weibo Jiang
Source:
Trends in food science & technology 2022 v.124 pp. 219-236
ISSN:
0924-2244
Subject:
antioxidants; aquaculture; ascorbic acid; bioremediation; chemical constituents of plants; fish; food industry; food waste; industrial applications; lemons; muscular atrophy; nutrient content; pectins; prebiotics; value added
Abstract:
... The last decade witnessed the rapid increase in the population worldwide, which fueled the development of food processing industry for fulfilling the daily demand for diversified food products. A massive amount of food by-products is simultaneously generated during the food processing. Generally, these by-products are discarded as food waste that results in adverse impacts on the environment and e ...
DOI:
10.1016/j.tifs.2022.04.019

17. An appraisal of critical factors configuring the composition of basil in minerals, bioactive secondary metabolites, micronutrients and volatile aromatic compounds

Author:
Michele Ciriello; Marios C. Kyriacou; Stefania De Pascale; Youssef Rouphael
Source:
Journal of food composition and analysis 2022 v.111 pp. 104582
ISSN:
0889-1575
Subject:
Ocimum basilicum; basil; biofortification; chemical constituents of plants; food composition; food industry; gastronomy; genetic variation; genotype; health promotion; light intensity; nutrient content; nutrition; phytochemicals; secondary metabolites; sensory evaluation; vegetable crops
Abstract:
... Combining health-promoting nutrition with gastronomic novelty is a major trend currently driving the agri-food sector. Basil (Ocimum basilicum L.) is a genetically diverse aromatic vegetable crop that combines rich phytochemical composition and enticing sensory profile. The current review examines how genetic variation underlies the phytochemical composition, nutrient composition, and volatile aro ...
DOI:
10.1016/j.jfca.2022.104582

18. An ayurvedic perspective along with in silico study of the drugs for the management of SARS-CoV-2

Author:
Abhay Jayprakash Gandhi; Jalpa Deepak Rupareliya; V.J. Shukla; Shilpa B. Donga; Rabinarayan Acharya
Source:
Journal of Ayurveda and integrative medicine 2022 v.13 no.1 pp. 100343
ISSN:
0975-9476
Subject:
Ayurvedic medicine; COVID-19 infection; Internet; Severe acute respiratory syndrome coronavirus 2; Zingiber officinale; antiviral properties; chemical constituents of plants; clinical trials; computer simulation; computer software; energy; humoral immunity; pandemic; prediction; quinine; vaccines; China
Abstract:
... COVID-19 is the disease caused by SARS-CoV2, it was identified in Wuhan, China, in 2019. It then extended across the globe and was termed as a pandemic in 2020. Though research work on its vaccine and drugs are carried out across the globe, it is even necessary to look over it through alternative sciences. The objective of this study is to look over the disease through Ayurvedic perspective, analy ...
DOI:
10.1016/j.jaim.2020.07.002

19. An evaluation of the phytochemical composition, antioxidant and cytotoxicity of the leaves of Litsea elliptica Blume – An ethnomedicinal plant from Brunei Darussalam

Author:
May Poh Yik Goh; Ajmal Faiz Kamaluddin; Terence Jit Loong Tan; Hartini Yasin; Hussein Taha; Abdalla Jama; Norhayati Ahmad
Source:
Saudi journal of biological sciences 2022 v.29 no.1 pp. 304-317
ISSN:
1319-562X
Subject:
2,2-diphenyl-1-picrylhydrazyl; Brunei; Litsea elliptica; aluminum chloride; antioxidant activity; antioxidants; apoptosis; carcinoma; cell lines; chemical constituents of plants; cytotoxicity; ethidium; fever; flavonoids; leaves; mitochondria; neoplasm cells; propidium; stomach; therapeutics; viability
Abstract:
... Litsea elliptica is traditionally believed to prevent and treat stomach ulcers, cancer, fever and headaches. This study investigates the phytochemical composition, antioxidant and cytotoxic effects of L. elliptica leaf extracts. The phytochemical content was determined via GCMS analysis and total phenolic content (TPC) and total flavonoid content (TFC) were analysed using the Folin-Ciocalteu and a ...
DOI:
10.1016/j.sjbs.2021.08.097

20. An insight into the anti-ulcerogenic potentials of medicinal herbs and their bioactive metabolites

Author:
Sowkat Jahan Shipa; Labony Khandokar; Md. Sazzadul Bari; Nazmul Qais; Mohammad Abdur Rashid; Md. Areeful Haque; Isa Naina Mohamed
Source:
Journal of ethnopharmacology 2022 v.293 pp. 115245
ISSN:
0378-8741
Subject:
Helicobacter pylori; chemical constituents of plants; cytokines; drug therapy; flora; gastrointestinal system; humans; metabolites; peptic ulcers; secretion; traditional medicine
Abstract:
... Peptic ulcer disease (PUD) ranks top among the most prominent gastrointestinal problems prevalent around the world. Long-term use of non-steroidal anti-inflammatory drugs, pathogenic infection by Helicobacter pylori, imbalances between gastrointestinal regulatory factors and pathological hyperacidity are major contributors towards the development of peptic ulcers. Although synthetic drugs of multi ...
DOI:
10.1016/j.jep.2022.115245