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1. Chemical Children

Author:
Peter Mansfield
Source:
Nutrition and health v.6 no.1 pp. 63-66
ISSN:
0260-1060
Subject:
asthma; children; nutrition; toxicity
Abstract:
... Following the Industrial Revolution technology has led to the identification and employment of a vast variety of chemicals. This has affected both agriculture and nutrition. The body's capacity to cope with chemicals is limited. Many, obviously, are toxic. What is safe is what is serviceable. Children, long before immune defences have been properly organised, are particularly vulnerable. Body chan ...
DOI:
10.1177/026010608800600106

2. Long-Term Home Jejunostomy Feeding of Young Children

Author:
Berit Björnestam; Carola Bengtsson; Sven Bergdahl; Yigael Finkel
Source:
Nutrition in clinical practice v.14 no.5 pp. 247-249
ISSN:
1941-2452
Subject:
asthma; children; gastroesophageal reflux; hernia; nervous system diseases; parents; surgery; vomiting
Abstract:
... Gastroesophageal reflux disease (GERD) is a motility disorder that occurs more frequently in children with neurological disease and in children with congenital esophageal anomalies or diaphragmatic hernia. Feeding difficulties and asthma may be caused by GER. Pharmacological and surgical treatment are successful in most cases. The authors describe 6 children with severe GER and asthma, who were tr ...
DOI:
10.1177/088453369901400506

3. Chronic pulmonary insufficiency in children and its effects on growth and development

Author:
Abrams, S.A.
Source:
Journal of nutrition 2001 v.131 no.3 pp. 938S-941S
ISSN:
0022-3166
Subject:
diet; malnutrition; nutritional intervention; nutrient deficiencies; congenital abnormalities; infant development; children; child development; nutrient requirements; asthma; cystic fibrosis; bronchopulmonary dysplasia; infants
Abstract:
... Conditions leading to chronic pulmonary insufficiency can affect infants and children. These can lead to growth failure and delayed development. Among the most common and severe of these are bronchopulmonary dysplasia (BPD) and cystic fibrosis. In addition to the respiratory consequences of these diseases, there is ample evidence that they lead to decreased growth as a result of decreased energy i ...
Handle:
10113/28455

4. Do rural and urban children have comparable asthma care utilization?

Author:
Yawn, B.P.; Mainous, A.G. III.; Love, M.M.; Hueston, W.
Source:
Journal of rural health 2001 v.17 no.1 pp. 32-39
ISSN:
0890-765X
Subject:
children; asthma; drug therapy; poverty; rural areas; urban areas; health insurance; demography; risk; Kentucky
Abstract:
... This study compares asthma-related health care visits and drug therapy for rural and nonrural Kentucky children with Medicaid health insurance in 1995. The 8,634 children with asthma had a mean age of 5.7 years. Ninety-two percent made at least one asthma office visit, and 13 percent were hospitalized. The urban and rural patterns of care for childhood asthma to in some potentially important ways. ...
DOI:
10.1111/j.1748-0361.2001.tb00252.x
PubMed:
11354720

5. Breast feeding, hydrolysate formulas and delayed introduction of selected foods in the prevention of food hypersensitivity and allergic disease

Author:
Chandra, Ranjit Kumar
Source:
Nutrition research 2002 v.22 no.1-2 pp. 125-135
ISSN:
0271-5317
Subject:
asthma; breast feeding; children; eczema; eggs; fish; food allergies; foods; hydrolysates; hydrolysis; infants; lactation; morbidity; mortality; peanuts
Abstract:
... Allergy and atopic disease is a major cause of morbidity and mortality, particularly in young children. In all infants, especially in those with parental history of allergy, exclusive breast feeding for 4 months or longer, dietary precautions by the lactating mother, use of a hydrolyzed formula, and delayed introduction of egg, fish, and peanut have considerable value in preventing food allergy, e ...

6. Children's diets: should they be taken with a pinch of salt?

Author:
Bussell, G.
Source:
Nutrition and food science 2002 v.32 no.6 pp. 231-236
ISSN:
0034-6659
Subject:
food intake; Dietary Guidelines; disease prevention; health promotion; heart diseases; children; asthma; bone density; obesity; osteoporosis; soft drinks; blood pressure; child nutrition
DOI:
10.1108/00346650210454226

7. Asthma and body weight change: a 20-year prospective community study of young adults

Author:
Hasler, G.; Gergen, P.J.; Ajdacic, V.; Gamma, A.; Eich, D.; Rossler, W.; Angst, J.
Source:
International journal of obesity 2006 v.30 no.7 pp. 1111-1118
ISSN:
0307-0565
Subject:
weight gain; adolescence; morbidity; risk factors; children; asthma; obesity; weight loss; adults; disease incidence
Abstract:
... Objective: There is increasing evidence for an association between asthma and body weight change. The objectives of these analyses were to examine the temporal relationships of this association and to explore the role of childhood depression as an explanatory factor. Methods: Data were derived from six subsequent semistructured interviews on health habits and health conditions from a single-age co ...
DOI:
10.1038/sj.ijo.0803215
PubMed:
16491113

8. Boys with high body masses have an increased risk of developing asthma: findings from the National Longitudinal Survey of Youth (NLSY)

Author:
Mannino, D.M.; Mott, J.; Ferdinands, J.M.; Camargo, C.A. Jr.; Friedman, M.; Greves, H.M.; Redd, S.C.
Source:
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2006 v.30 no.1 pp. 6-13
ISSN:
0307-0565
Subject:
boys; body mass index; asthma; risk factors; risk assessment; disease incidence; children; gender differences; girls
Abstract:
... Objective: To determine the relation between body mass index and the development of asthma in children. Design: Prospective study of 4393 asthma-free children followed for up to 14 years. Setting: Children of participants in the National Longitudinal Survey of Youth. Methods: Analysis was limited to children who were followed from birth and were asthma-free during the first 24 months of life. The ...
PubMed:
16344843

9. Ambient Air Pollution and Daily Pediatric Hospitalizations for Asthma (5 pp)

Author:
James Regens
Source:
Environmental science and pollution research international 2007 v.14 no.1 pp. 19-23
ISSN:
0944-1344
Subject:
adverse effects; air; air pollution; air quality; asthma; children; cities; environmental exposure; health services; hospitals; human health; mortality; nitrogen dioxide; pollutants; public health; regression analysis; relative risk; risk factors; scientists; smoking (habit); temperature; time series analysis; Europe; Oklahoma
Abstract:
... BACKGROUND, AIM AND SCOPE: A series of severe air pollution episodes in Europe and North America prior to 1960 have focused scientific and regulatory attention on the adverse effects of air pollution on human health. As a consequence of significant reductions in ambient air pollution levels in the intervening years, scientists and public health officials have become more concerned with the potenti ...
DOI:
10.1065/espr2006.08.333

10. Increasing body mass index from age 5 to 14 years predicts asthma among adolescents: evidence from a birth cohort study

Author:
Mamun, A.A.; Lawlor, D.A.; Alati, R.; O'Callaghan, M.J.; Williams, G.M.; Najman, J.M.
Source:
International journal of obesity : journal of the International Association for the Study of Obesity 2007 v.31 no.4 pp. 578-583
ISSN:
0307-0565
Subject:
body mass index; child nutrition; children; adolescent nutrition; prediction; asthma; adolescents; obesity; disease prevalence; risk assessment; cohort studies; correlation; Queensland
Abstract:
... Background: Obesity and asthma are common disorders, and the prevalence of both has increased in recent decades. It has been suggested that increases in the prevalence of obesity might in part explain the increase in asthma prevalence. This study aims to examine the prospective association between change in body mass index (BMI) z-score between ages 5 and 14 years and asthma symptoms at 14 years. ...
DOI:
10.1038/sj.ijo.0803571
PubMed:
17384659

11. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age

Author:
Camargo, Carlos A. Jr.; Rifas-Shiman, Sheryl L.; Litonjua, Augusto A.; Rich-Edwards, Janet W.; Weiss, Scott T.; Gold, Diane R.; Kleinman, Ken; Gillman, Matthew W.
Source:
American journal of clinical nutrition 2007 v.85 no.3 pp. 788-795
ISSN:
0002-9165
Subject:
nutrient intake; human diseases; pregnant women; cohort studies; risk factors; risk assessment; children; vitamin D; asthma; maternal nutrition; vitamin deficiencies; maternal-fetal transfer; pathogenesis; food frequency questionnaires; disease incidence
Abstract:
... BACKGROUND:Vitamin D deficiency and asthma are common at higher latitudes. Although vitamin D has important immunologic effects, its relation with asthma is unknown. OBJECTIVE:We hypothesized that a higher maternal intake of vitamin D during pregnancy is associated with a lower risk of recurrent wheeze in children at 3 y of age. DESIGN:The participants were 1194 mother-child pairs in Project Viva- ...
PubMed:
17344501

12. Maternal vitamin D intake during pregnancy and early childhood wheezing

Author:
Devereux, Graham; Litonjua, Augusto A.; Turner, Stephen W.; Craig, Leone CA; McNeill, Geraldine; Martindale, Sheelagh; Helms, Peter J.; Seaton, Anthony; Weiss, Scott T.
Source:
American journal of clinical nutrition 2007 v.85 no.3 pp. 853-859
ISSN:
0002-9165
Subject:
human diseases; pregnant women; cohort studies; risk factors; disease severity; pregnancy; children; vitamin D; asthma; maternal nutrition; vitamin deficiencies; maternal-fetal transfer; pathogenesis; infants; food frequency questionnaires; disease incidence; Scotland
Abstract:
... BACKGROUND: Maternal intake of vitamin D in pregnancy is a potentially modifiable but understudied risk factor for the development of asthma in children. OBJECTIVE: We investigated whether maternal vitamin D intake in pregnancy is associated with decreased risks of wheezing symptoms in young children. DESIGN: Subjects were from a birth cohort recruited in utero with the primary objective of identi ...
PubMed:
17344509

13. Foods, nutrients and portions consumed by a sample of Australian children aged 16-24 months

Author:
WEBB, Karen; RUTIHAUSER, Ingrid; KNEZEVIC, Natalia
Source:
Nutrition & dietetics 2008 v.65 no.1 pp. 56-65
ISSN:
1446-6368
Subject:
Adequate Intakes; Australians; Estimated Average Requirement; ascorbic acid; asthma; atopy; beverages; boys; calcium; children; dietary fiber; energy intake; energy requirements; food groups; food records; fruits; gender differences; girls; grains; hospitals; ingestion; iron; meat; milk; monitoring; nutrients; portion size; pregnant women; sodium; t-test; vegetables; vitamin A
Abstract:
... To describe the diet of a sample of Australian children aged 16-24 months with regard to the amounts of foods and nutrients consumed. Cross-sectional data collected from participants in a five-year randomised trial of the primary prevention of asthma. Pregnant women with a family history of atopy were recruited from six hospital antenatal clinics in western Sydney. At the 18-month assessment, care ...
DOI:
10.1111/j.1747-0080.2007.00224.x

14. Higher Environmental Relative Moldiness Index (ERMIˢᵐ) values measured in Detroit homes of severely asthmatic children

Author:
Stephen Vesper; Craig McKinstry; Richard Haugland; Lucas Neas; Edward Hudgens; Brooke Heidenfelder; Jane Gallagher
Source:
Science of the total environment 2008 v.394 no.1 pp. 192-196
ISSN:
0048-9697
Subject:
Aspergillus niger; asthma; bags; children; drug therapy; polymerase chain reaction; remediation; risk
Abstract:
... Sieved vacuum bag dust from the homes of 143 children in Detroit was analyzed by mold specific quantitative PCR (MSQPCR) and the Environmental Relative Moldiness Index (ERMIˢᵐ) was calculated for each home. Children living in these homes were grouped as non-asthmatic (n=83), moderately asthmatic (n=28) and severely asthmatic (n=32) based on prescription medication usage for their asthma management ...
DOI:
10.1016/j.scitotenv.2008.01.031
PubMed:
18280542

15. Prevalence of asthma in a general population cohort of farm children: comparison of estimates based on parental report and medical record review

Author:
Greenlee, Robert T.; Chyou, Po-Huang; Kieke, Amy; Naik, Yashoda G.; Kirkhorn, Steven
Source:
Journal of agromedicine 2008 v.13 no.4 pp. 225-231
ISSN:
1059-924X
Subject:
asthma; rural health; children; disease diagnosis; agrochemicals; case studies; Midwestern United States
DOI:
10.1080/10599240802454593
PubMed:
19064414

16. Relation of Adult-Onset Asthma to Coronary Heart Disease and Stroke

Author:
Onufrak, Stephen J.; Abramson, Jerome L.; Austin, Harland D.; Holguin, Fernando; McClellan, William M.; Vaccarino, L. Viola
Source:
American journal of cardiology 2008 v.101 no.9 pp. 1247-1252
Subject:
human diseases; men; humans; women; myocardial ischemia; age; risk assessment; children; asthma; stroke
Abstract:
... Asthma was associated with atherosclerotic disease in several studies, with evidence that this association may be limited to women. However, most previous studies failed to account for the heterogeneity of asthma subtypes. We previously reported increased carotid intima-medial thickness in women with adult-onset asthma. In this study, the association of adult- and child-onset asthma with incident ...
Handle:
10113/32348
DOI:
10.1016/j.amjcard.2007.12.024

17. Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children

Author:
Wang, Jinhui; Xu, Yongchen; Zhao, Hong; Sui, Hong; Liang, Hongyan; Jiang, Xiaofeng
Source:
Molecular biology reports 2009 v.36 no.6 pp. 1549-1553
ISSN:
0301-4851
Subject:
3' untranslated regions; asthma; children; haplotypes; linkage disequilibrium; single nucleotide polymorphism
Abstract:
... We investigated the allele and genotype frequencies of two common CRTH2 single nucleotide polymorphisms (SNPs) [G1544C and A1651G (rs 545659)] in the 3'-untranslated region and the relationship between these SNPs and serum IL-13 levels in Chinese children patients with asthma. For G1544C and A1651G SNPs, there were significant differences in allele and genotype frequencies between asthma patients ...
DOI:
10.1007/s11033-008-9349-6
PubMed:
18777142

18. Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence

Author:
Shankardass, Ketan; McConnell, Rob; Jerrett, Michael; Milam, Joel; Richardson, Jean; Berhane, Kiros
Source:
Proceedings of the National Academy of Sciences of the United States of America 2009 v.106 no.30 pp. 12406-12411
ISSN:
0027-8424
Subject:
air pollution; asthma; childhood; children; cohort studies; education; households; models; pregnancy; questionnaires; risk; smoking (habit); socioeconomic status; California
Abstract:
... Exposure to traffic-related pollution (TRP) and tobacco smoke have been associated with new onset asthma in children. Psychosocial stress-related susceptibility has been proposed to explain social disparities in asthma. We investigated whether low socioeconomic status (SES) or high parental stress modified the effect of TRP and in utero tobacco smoke exposure on new onset asthma. We identified 2,4 ...
DOI:
10.1073/pnas.0812910106
PubMed:
19620729
PubMed Central:
PMC2718368

19. Pediatric Asthma : An Integrative Approach to Care

Author:
John David Mark
Source:
Nutrition in clinical practice v.24 no.5 pp. 578-588
ISSN:
1941-2452
Subject:
alternative medicine; asthma; childhood; children; environmental factors; guidelines; inflammation; lung function; lungs; phenotype; young adults
Abstract:
... Asthma in children and young adults is a complex disease with many different phenotypic expressions. Diagnosis is often made based on history and lung function including measuring airway reversibility. However, in children younger than 6 years of age, the diagnosis is more difficult because many children wheeze in the first 4‐6 years of life, especially with viral infections. For those children, a ...
DOI:
10.1177/0884533609342446

20. Prenatal and childhood Mediterranean diet and the development of asthma and allergies in children

Author:
Chatzi, Leda; Kogevinas, Manolis
Source:
Public health nutrition 2009 v.12 no.9A pp. 1629-1634
ISSN:
1475-2727
Subject:
diet; legumes; grain crops; margarine; seafoods; children; fetus; asthma; maternal nutrition; traditional foods; fish; nuts; vegetables; atopy; red meat; Greece; Spain; Mexico
DOI:
10.1017/S1368980009990474
PubMed:
19689832

21. Relationship between indoor environment and asthma and wheeze severity among rural children and adolescents

Author:
Lawson, Joshua A.; Dosman, James A.; Rennie, Donna C.; Beach, Jeremy; Newman, Stephen C.; Senthilselvan, Ambikaipakan
Source:
Journal of agromedicine 2009 v.14 no.2 pp. 277-285
ISSN:
1059-924X
Subject:
asthma; rural families; children; indoor environmental quality; case studies; Canada
DOI:
10.1080/10599240902772910
PubMed:
19437289

22. Sensitization to common food and inhalant allergens in children attending Allergy and Asthma Pediatric Clinic in Doha, Qatar

Author:
Kerkadi, Abdelhamid; Althani, Asma; Al-Boainain, Amina; Janahi, Ibrahim; Singh, Rajiv
Source:
Journal of food, agriculture & environment 2009 v.7 no.2 pp. 213-217
ISSN:
1459-0255
Subject:
children; food allergies; allergens; inhalation exposure; asthma; Qatar

23. Use of multivitamin supplements in relation to allergic disease in 8-y-old children

Author:
Marmsjö, Kristin; Rosenlund, Helen; Kull, Inger; Håkansson, Niclas; Wickman, Magnus; Pershagen, Göran; Bergström, Anna
Source:
American journal of clinical nutrition 2009 v.90 no.6 pp. 1693-1698
ISSN:
0002-9165
Subject:
nutrient intake; questionnaires; disease prevention; multivitamin supplements; risk factors; eczema; children; asthma; lifestyle; food allergies; disease incidence; Sweden
Abstract:
... BACKGROUND: Multivitamins are frequently consumed by children, but it is unclear whether this affects the risk of allergic disease. OBJECTIVE: We sought to study the association between multivitamin supplementation and allergic disease in 8-y-old children. DESIGN: Data were obtained from a Swedish birth cohort study. Information on lifestyle factors, including use of vitamin supplements, environme ...
DOI:
10.3945/ajcn.2009.27963
PubMed:
19864411

24. Asthma and obesity in childhood: on the road ahead

Author:
Peroni, D.G.; Pietrobelli, A.; Boner, A.L.
Source:
International journal of obesity 2010 v.34 no.4 pp. 599-605
ISSN:
0307-0565
Subject:
human diseases; phenotype; physical activity; inflammation; signs and symptoms (animals and humans); children; chronic diseases; asthma; obesity; lungs; breathing; child nutrition; disease diagnosis
Abstract:
... Epidemiological data show a link between asthma and obesity, suggesting many different mechanisms that may underlie the association. However, diagnosis of asthma is often self-reported by patients or caregivers. Definition of asthma is crucial, particularly in childhood. Obesity can be associated with symptoms commonly attributed to asthma, such as wheezing, dyspnoea and sleep apnoea. Obese subjec ...
DOI:
10.1038/ijo.2009.273
PubMed:
20065975

25. Concentration of IgE in children during ragweed pollination season

Author:
Špehar, Mirjana; Dodig, Slavica; Hrga, Ivana; Simić, Draženka; Turkalj, Mirjana; Venus, Miroslav
Source:
Aerobiologia 2010 v.26 no.1 pp. 29-34
ISSN:
0393-5965
Subject:
Ambrosia artemisiifolia; asthma; blood serum; chest; children; cities; dyspnea; environmental factors; immunoglobulin E; nose; pollen; pollination; pruritus; rhinitis; rural areas; seasonal variation; urban areas
Abstract:
... Genetic and environmental factors are responsible for running allergic diseases. The aim of this study was to compare the values of total- (t-IgE) and allergen-specific IgE (s-IgE) to Ambrosia artemisiifolia L. (Amb a) in children with sensitization to Amb a during ragweed pollination season, who experienced seasonal symptoms of allergic rhinitis (rhinorrhea, post-nasal drip, nasal congestion, itc ...
DOI:
10.1007/s10453-009-9140-8

26. Didgeridoo Playing and Singing to Support Asthma Management in Aboriginal Australians

Author:
Eley, Robert; Gorman, Don
Source:
Journal of rural health 2010 v.26 no.1 pp. 100-104
ISSN:
0890-765X
Subject:
Australians; adolescents; adults; asthma; boys; children; compliance; females; girls; high school students; high schools; indigenous peoples; lung function; males; music
Abstract:
... Context: Asthma affects over 15% of Australian Aboriginal people. Compliance in asthma management is poor. Interventions that will increase compliance are required. Purpose: The purpose of the study was to determine whether Aboriginal children, adolescents and adults would engage in music lessons to increase their knowledge of asthma and support management of their asthma. Methods: Participants we ...
DOI:
10.1111/j.1748-0361.2009.00256.x
PubMed:
20105276

27. Maternal overweight before pregnancy and asthma in offspring followed for 8 years

Author:
Scholtens, S.; Wijga, A.H.; Brunekreef, B.; Kerkhof, M.; Postma, D.S.; Oldenwening, M.; Jongste, J.C. de; Smit, H.A.
Source:
International journal of obesity 2010 v.34 no.4 pp. 606-613
ISSN:
0307-0565
Subject:
adrenal cortex hormones; human diseases; drug therapy; mothers; hormone supplements; overweight; cohort studies; signs and symptoms (animals and humans); longitudinal studies; fetal development; pregnancy; children; asthma; maternal nutrition; body mass index; breathing; Netherlands
Abstract:
... Objective: The aim of this study was to investigate the association between maternal overweight before pregnancy and offspring asthma in an ongoing birth cohort study. Maternal overweight may affect the pulmonary and immunological development of the fetus in utero because of the increased levels of inflammatory factors associated with being overweight and thereby increase the asthma risk in childh ...
DOI:
10.1038/ijo.2009.194
PubMed:
19786965

28. Probiotics in the management of children with allergy and other disorders of intestinal inflammation

Author:
J. Vanderhoof; S. Mitmesser
Source:
Beneficial microbes 2010 v.1 no.4 pp. 351-356
ISSN:
1876-2891
Subject:
Bifidobacterium; Lactobacillus; asthma; atopic dermatitis; bacteria; children; colitis; diarrhea; gastrointestinal system; hospitals; inflammation; intestinal microorganisms; mucosal immunity; probiotics; rhinitis; risk reduction
Abstract:
... Soon after birth, the human gastrointestinal tract quickly becomes colonised by a variety of bacterial species. Throughout life the gastrointestinal tract continues to serve as host to a complex society of nonpathological bacteria. Microorganisms, such as probiotics, have the potential to modulate mucosal immune response and reduce gastrointestinal inflammation caused by a variety of infectious an ...
DOI:
10.3920/BM2010.0034

29. Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection

Author:
Numata, Mari; Chu, Hong Wei; Dakhama, Azzeddine; Voelker, Dennis R.
Source:
Proceedings of the National Academy of Sciences of the United States of America 2010 v.107 no.1 pp. 320-325
ISSN:
0027-8424
Subject:
Toll-like receptor 4; asthma; children; cytopathogenicity; elderly; epithelial cells; human cell lines; inflammation; interferon-gamma; interleukin-6; lipopolysaccharides; lungs; mice; morbidity; mortality; people; phospholipids; surfactants; therapeutics; vaccines; viruses
Abstract:
... Respiratory syncytial virus (RSV) is the most common cause of hospitalization for respiratory tract infection in young children. It is also a significant cause of morbidity and mortality in elderly individuals and in persons with asthma and chronic obstructive pulmonary disease. Currently, no reliable vaccine or simple RSV antiviral therapy is available. Recently, we determined that the minor pulm ...
DOI:
10.1073/pnas.0909361107
PubMed:
20080799
PubMed Central:
PMC2806703

30. Visually observed mold and moldy odor versus quantitatively measured microbial exposure in homes

Author:
Reponen, Tiina; Singh, Umesh; Schaffer, Chris; Vesper, Stephen; Johansson, Elisabet; Adhikari, Atin; Grinshpun, Sergey A.; Indugula, Reshmi; Ryan, Patrick; Levin, Linda; LeMasters, Grace
Source:
Science of the total environment 2010 v.408 no.22 pp. 5565-5574
ISSN:
0048-9697
Subject:
air; asthma; children; epidemiological studies; fungal spores; odors; quantitative polymerase chain reaction
Abstract:
... The main study objective was to compare different methods for assessing mold exposure in conjunction with an epidemiologic study on the development of children's asthma. Homes of 184 children were assessed for mold by visual observations and dust sampling at child's age 1 (Year 1). Similar assessment supplemented with air sampling was conducted in Year 7. Samples were analyzed for endotoxin, (1-3) ...
DOI:
10.1016/j.scitotenv.2010.07.090
PubMed:
20810150
PubMed Central:
PMC2972663

31. A Medical Nutrition Therapy Primer for Childhood Asthma: Current and Emerging Perspectives

Author:
McCloud, Emily; Papoutsakis, Constantina
Source:
Journal of the American Dietetic Association 2011 v.111 no.7 pp. 1052-1064
ISSN:
0002-8223
Subject:
foods; drug therapy; bronchodilators; gastroesophageal reflux; chest; adrenal cortex hormones; eating habits; mouth; risk factors; disease control; children; chronic diseases; asthma; nutrition assessment; childhood obesity; childhood; food allergies; weight control; cough; healthy diet; Mediterranean diet; diet therapy; United States
Abstract:
... Asthma is the most common chronic disease in children. Prevalence has increased in the past 2 decades and has reached a plateau of approximately 9% of children in the United States, affecting about 6.7 million children. The increased prevalence of childhood asthma has paralleled the increased prevalence in childhood obesity. Changes in diet have also been implicated in the increased prevalence of ...
DOI:
10.1016/j.jada.2011.04.005
PubMed:
21703384

32. A postmarketing evaluation of the frequency of use and safety of live attenuated influenza vaccine use in nonrecommended children younger than 5 years

Author:
Patricia Tennis; Seth L. Toback; Elizabeth Andrews; Lisa J. McQuay; Christopher S. Ambrose
Source:
Vaccine 2011 v.29 no.31 pp. 4947-4952
ISSN:
0264-410X
Subject:
asthma; children; databases; guidelines; health insurance; immunocompetence; influenza; vaccination; vaccines; United States
Abstract:
... The 2007 US approval for use of live attenuated influenza vaccine (LAIV) in children aged 24–59 months included precautions against use in (1) children <24 months and children aged 24–59 months with (2) asthma, (3) recurrent wheezing, and (4) altered immunocompetence. A postmarketing commitment was initiated to monitor LAIV use and the frequency of select safety outcomes in these cohorts. Vaccinat ...
DOI:
10.1016/j.vaccine.2011.04.113

33. A spatial-temporal regression model to predict daily outdoor residential PAH concentrations in an epidemiologic study in Fresno, CA

Author:
Elizabeth M. Noth; S. Katharine Hammond; Gregory S. Biging; Ira B. Tager
Source:
Atmospheric environment 2011 v.45 no.14 pp. 2394-2403
ISSN:
1352-2310
Subject:
air pollution; asthma; atmospheric chemistry; children; combustion; epidemiological studies; fuels; heat; land use; landforms; meteorological data; models; polycyclic aromatic hydrocarbons; regression analysis; risk; traffic; California
Abstract:
... BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs) are generated as a byproduct of combustion, and are associated with respiratory symptoms and increased risk of asthma attacks. OBJECTIVES: To assign daily, outdoor exposures to participants in the Fresno Asthmatic Children’s Environment Study (FACES) using land use regression models for the sum of 4-, 5- and 6-ring PAHs (PAH456). METHODS: PAH dat ...
DOI:
10.1016/j.atmosenv.2011.02.014

34. Acute effects of air pollution on pediatric asthma exacerbation: Evidence of association and effect modification

Author:
E. Samoli; P.T. Nastos; A.G. Paliatsos; K. Katsouyanni; K.N. Priftis
Source:
Environmental research 2011 v.111 no.3 pp. 418-424
ISSN:
0013-9351
Subject:
acute effects; air pollution; asthma; children; confidence interval; hospitals; influenza; monitoring; nitrogen dioxide; ozone; particulates; regression analysis; spring; sulfur dioxide; summer; weather; winter; Greece
Abstract:
... We investigated the short-term effects of particulate matter with aerodynamic diameter <10μg/m³ (PM₁₀), sulfur dioxide (SO₂), nitrogen dioxide (NO₂) and ozone (O₃) on pediatric asthma emergency admissions in Athens, Greece over the period 2001–2004. We explored effect modification patterns by season, sex, age and by the presence of desert dust transported mainly from the Sahara area. We used daily ...
DOI:
10.1016/j.envres.2011.01.014

35. Air quality trends and potential health effects – Development of an aggregate risk index

Author:
Pierre Sicard; Olivia Lesne; Nicolas Alexandre; Antoine Mangin; Rémy Collomp
Source:
Atmospheric environment 2011 v.45 no.5 pp. 1145-1153
ISSN:
1352-2310
Subject:
Mediterranean climate; additive effect; adverse effects; air; air pollution; air quality; asthma; atmospheric chemistry; cerebrovascular disorders; children; data collection; emissions; health hazards; heart diseases; models; morbidity; mortality; nitrogen dioxide; ozone; pollutants; prediction; public health; relative risk; sulfur dioxide; traffic; warm season; France
Abstract:
... The “Provence Alpes Côte d’Azur” (PACA) region, in the South East of France, is one of Europe’s regions most influenced by the atmospheric pollution. During the last 15 years, the industrial emissions decrease caused an evolution of the atmospheric pollution nature. Nowadays, atmospheric pollution is more and more influenced by the road traffic, the dominating pollution source in urban zones for t ...
DOI:
10.1016/j.atmosenv.2010.12.052

36. Association between β+252 tumour necrosis factor polymorphism and asthma in western Saudi children

Author:
Essam H. Jiffri; Nasser A. Elhawary
Source:
Saudi journal of biological sciences 2011 v.18 no.1 pp. 107-111
ISSN:
1319-562X
Subject:
alleles; asthma; childhood; children; genotype; genotyping; infants; introns; loci; lymphotoxin; pathogenesis; polymerase chain reaction; restriction fragment length polymorphism; risk; Saudi Arabia
Abstract:
... There is strong evidence that supports the role of tumour necrosis factors (TNF-alpha/beta) as common genetic factors, located on 6p21.1–6p21.3 loci, in the pathogenesis of asthma disease. In this study, we extended our research work on TNFA to include the genotyping of Saudi asthmatic children as regards to TNFB gene (namely as lymphotoxin-α, LTA). We examined 60 asthmatic Saudi children compared ...
DOI:
10.1016/j.sjbs.2010.10.006
PubMed:
23961111
PubMed Central:
PMC3730738

37. Association of Polymorphisms of STAT6 and SO₂ with Chinese Childhood Asthma: a Case-control Study

Author:
Qiang WANG; Xue Tao BAI; Dong Qun XU; Hong LI; Chun Yu XU; Jian Long FANG
Source:
Biomedical and environmental sciences 2011 v.24 no.6 pp. 670-677
ISSN:
0895-3988
Subject:
Chinese people; air; air pollution; alleles; asthma; case-control studies; childhood; children; computer software; exons; gene frequency; genotype; influenza; nitrogen dioxide; pollutants; risk factors; single nucleotide polymorphism; statistical analysis; sulfur dioxide
Abstract:
... OBJECTIVE: To investigate the association of polymorphisms of STAT6 gene and air pollutants of PM₁₀, NO₂, and SO₂, with asthma in Chinese children. METHODS: 418 subjects aged 14 years and under were recruited in a case-control study. The association between STAT6 polymorphisms and childhood asthma were tested by allele frequency, genotype analysis, and MDR analysis. Exposure to outdoor air polluta ...
DOI:
10.3967/0895-3988.2011.06.012

38. Atopy history and the genomics of wheezing after influenza vaccination in children 6–59 months of age

Author:
E. Kathryn Miller; Logan Dumitrescu; Chelsea Cupp; Stacy Dorris; Sallee Taylor; Robert Sparks; Diane Fawkes; Virginia Frontiero; Anne M. Rezendes; Colin Marchant; Kathryn M. Edwards; Dana C. Crawford
Source:
Vaccine 2011 v.29 no.18 pp. 3431-3437
ISSN:
0264-410X
Subject:
DNA; asthma; atopy; children; clinical trials; genomics; influenza; risk factors; single nucleotide polymorphism; surveys; vaccination; vaccines; United States
Abstract:
... BACKGROUND: A multinational clinical trial compared the safety and efficacy of intranasal trivalent live attenuated influenza vaccine (LAIV) with intramuscular trivalent inactivated vaccine (TIV) in very young children prior to the 2004–5 influenza season [1]. Wheezing was noted more often in recipients of LAIV and laboratory-confirmed influenza infection was noted more often in recipients of TIV. ...
DOI:
10.1016/j.vaccine.2011.02.071
PubMed:
21396408
PubMed Central:
PMC3334304

39. Biochemical effects of ozone on asthma during postnatal development

Author:
Richard L. Auten; W. Michael Foster
Source:
Biochimica et biophysica acta 2011 v.1810 no.11 pp. 1114-1119
ISSN:
0304-4165
Subject:
adults; antioxidants; asthma; children; infancy; ozone; postnatal development; respiratory physiology
Abstract:
... BACKGROUND: Ozone exposure during early life has the potential to contribute to the development of asthma as well as to exacerbate underlying allergic asthma. SCOPE OF REVIEW: Developmentally regulated aspects of sensitivity to ozone exposure and downstream biochemical and cellular responses. MAJOR CONCLUSIONS: Developmental differences in antioxidant defense responses, respiratory physiology, and ...
DOI:
10.1016/j.bbagen.2011.01.008
PubMed:
21276837
PubMed Central:
PMC3106122

40. Exposure to Traffic-Related Air Pollutants in the Perinatal Period of Life in Relation to Respiratory Health in Infancy

Author:
G. Koppen; K. Bloemen; A. Colles; V. Nelen; K. Desager; G. Schoeters
Source:
Critical reviews in environmental science and technology 2011 v.41 no.22 pp. 2003-2025
ISSN:
1547-6537
Subject:
cohort studies; pollutants; children; infancy; air; asthma; childhood; air pollution; perinatal period
Abstract:
... The role of air pollution exposure on the development of asthma remains unclear. This can only be answered by prospective cohort studies. The authors give an overview of cohort studies focusing mainly on the role of early exposure, investigating the association between outdoor exposure early in life and respiratory or allergy symptoms in the growing children. Based on those studies, there is a sug ...
DOI:
10.1080/10643389.2010.495643

41. Exposure to moulds and actinomycetes in Alpine farms: A nested environmental study of the PASTURE cohort

Author:
S. Roussel; B. Sudre; G. Reboux; M. Waser; G. Buchele; M. Vacheyrou; J.C. Dalphin; L. Millon; C. Braun-Fahrländer; E. von Mutius; R. Piarroux
Source:
Environmental research 2011 v.111 no.6 pp. 744-750
ISSN:
0013-9351
Subject:
cattle feeding; Actinomycetales; summer; Penicillium; pastures; farms; air; Absidia; grasses; spores; winter; cattle; yeasts; farming systems; children; asthma; Eurotium; farmers; airborne microorganisms; silage; Cladosporium; Germany; France; Switzerland
Abstract:
... Several studies have suggested that children exposed to a farm environment are protected against allergies and asthma. The present work is an environmental study nested within the PASTURE cohort and includes 97 farmers and 74 non-farmers in three regions of the Alpine Arc (Switzerland, France and Germany). The objectives were to determine and compare the fungi and actinomycetes present in farming ...
DOI:
10.1016/j.envres.2011.05.002

42. Hospital admissions for asthma and acute bronchitis in El Paso, Texas: Do age, sex, and insurance status modify the effects of dust and low wind events?

Author:
Sara E. Grineski; Joan G. Staniswalis; Priyangi Bulathsinhala; Yanlei Peng; Thomas E. Gill
Source:
Environmental research 2011 v.111 no.8 pp. 1148-1155
ISSN:
0013-9351
Subject:
air; asthma; boys; bronchitis; children; confidence interval; elderly; environmental factors; girls; health insurance; humans; nitrogen dioxide; particulates; pollutants; regression analysis; risk; sublethal effects; temperature; wind; Texas
Abstract:
... BACKGROUND: El Paso County (Texas) is prone to still air inversions and is one of the dust “hot spots” in North America. In this context, we examined the sub-lethal effects of airborne dust and low wind events on human respiratory health (i.e., asthma and acute bronchitis) between 2000 and 2003, when 110 dust and 157 low wind events occurred. Because environmental conditions may not affect everyon ...
DOI:
10.1016/j.envres.2011.06.007
PubMed:
21782162
PubMed Central:
PMC3572938

43. Infant and early childhood dietary predictors of overweight at age 8 years in the CAPS population

Author:
Garden, F.L.; Marks, G.B.; Almqvist, C.; Simpson, J.M.; Webb, K.L.
Source:
European journal of clinical nutrition 2011 v.65 no.4 pp. 454-462
ISSN:
0954-3007
Subject:
Australians; adiposity; asthma; body mass index; childhood; children; cohort studies; cookies; crackers; dairy products; energy expenditure; food intake; food records; grain foods; meat; obesity; planning; public policy; regression analysis; risk; waist circumference
Abstract:
... Background/Objectives: Programs to address obesity are a high priority for public policy especially for young children. Research into dietary determinants of obesity is challenging but important for rational planning of interventions to prevent obesity, given that both diet and energy expenditure influence weight status. We investigated whether early life dietary factors were predictive of weight ...
DOI:
10.1038/ejcn.2011.7

44. Intake of antioxidants during pregnancy and the risk of allergies and asthma in the offspring

Author:
Nwaru, B.I.; Erkkola, M.; Ahonen, S.; Kaila, M.; Kronberg-Kippilä, C.; Ilonen, J.; Simell, O.; Knip, M.; Veijola, R.; Virtanen, S.M.
Source:
European journal of clinical nutrition 2011 v.65 no.8 pp. 937-943
ISSN:
0954-3007
Subject:
risk; food intake; free radicals; cohort studies; rhinitis; eczema; magnesium; pregnancy; children; insulin-dependent diabetes mellitus; asthma; regression analysis; immune response; food frequency questionnaires; childhood; antioxidants; prediction
Abstract:
... Background/Objectives: The potential immune functions related to the damages induced by oxygen-free radicals suggest that antioxidants may have a role in the development of allergies. The objective was to investigate the association between maternal intake of antioxidants during pregnancy and the risk of asthma, rhinitis and eczema in 5-year-old children. Subjects/Methods: This study was on the ba ...
DOI:
10.1038/ejcn.2011.67

45. Investigation of different approaches to reduce allergens in asthmatic children's homes — The Breath of Fresh Air Project, Cornwall, United Kingdom

Author:
Susan Ann Eick; George Richardson
Source:
Science of the total environment 2011 v.409 no.19 pp. 3628-3633
ISSN:
0048-9697
Subject:
Glycyphagus domesticus; air; air quality; allergens; asthma; children; environmental impact; exercise; heat; home furnishings; United Kingdom
Abstract:
... During 2001 to 2004, a study was conducted to assess the indoor environmental and health impact of installing allergen-reducing interventions in the homes of asthmatic children. Based on the results of a pilot study, to determine an intervention that would provide improved symptom scores and a reduction in house dust mite allergen (Der p 1), mechanical ventilation and heat recovery (MVHR) systems ...
DOI:
10.1016/j.scitotenv.2011.06.011
PubMed:
21741678

46. Lack of association of mercury with risk of wheeze and eczema in Japanese children: The Osaka Maternal and Child Health Study

Author:
Yoshihiro Miyake; Keiko Tanaka; Akira Yasutake; Satoshi Sasaki; Yoshio Hirota
Source:
Environmental research 2011 v.111 no.8 pp. 1180-1184
ISSN:
0013-9351
Subject:
risk; Japanese people; breast feeding; fish consumption; mercury; mothers; surveys; eczema; confidence interval; odds ratio; children; pregnancy; asthma; immune system; childhood; education; siblings; Japan
Abstract:
... Mercury can have profound and complicated effects on the immune system, and epidemiological evidence regarding the relationship between mercury exposure and allergic disorders has been sparse. We investigated the associations between mercury levels in maternal and children's hair and the risk of wheeze and eczema in Japanese children at 29–39 months of age. Study subjects were 582 Japanese mother– ...
DOI:
10.1016/j.envres.2011.07.003

47. Lead poisoning and asthma among low-income and African American children in Saginaw, Michigan

Author:
Pamela Pugh Smith; Jerome O. Nriagu
Source:
Environmental research 2011 v.111 no.1 pp. 81-86
ISSN:
0013-9351
Subject:
African Americans; asthma; blood; children; cross-sectional studies; databases; households; lead; lead poisoning; monitoring; remediation; risk factors; Michigan
Abstract:
... OBJECTIVE: We sought to ascertain whether asthmatic children are more likely to have elevated blood lead levels (EBLLs), BLLs≥10μg/dL, than non-asthmatic children. Household risk factors associated with both lead and asthma were examined. METHOD: We undertook a cross-sectional study involving children residing in mainly low-income and minority households in Michigan which were identified by the St ...
DOI:
10.1016/j.envres.2010.11.007

48. Life style and home environment are associated with racial disparities of asthma and allergy in Northeast Texas children

Author:
Yuexia Sun; Jan Sundell
Source:
Science of the total environment 2011 v.409 no.20 pp. 4229-4234
ISSN:
0048-9697
Subject:
day care centers; races; medical facilities; risk factors; eczema; elementary schools; environmental exposure; children; Whites; asthma; pets; air conditioning; smoking (habit); socioeconomic status; lifestyle; cross-sectional studies; Mexican Americans; Texas
Abstract:
... A high prevalence and racial disparities in asthma and allergy have been observed in American children. This study aimed to identify risk factors for asthma and allergy among children, and their contribution to racial disparities in allergy prevalence. A population-based cross-sectional study was carried out among children aged 1–8years in Northeast Texas 2008–2009. The health conditions, life sty ...
DOI:
10.1016/j.scitotenv.2011.07.011
PubMed:
21802705

49. Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review

Author:
Reilly, J.J.; Kelly, J.
Source:
International journal of obesity 2011 v.35 no.7 pp. 891-898
ISSN:
0307-0565
Subject:
adolescence; adolescents; adulthood; adults; animal ovaries; asthma; childhood obesity; children; diabetes; hypertension; long term effects; morbidity; mortality; myocardial ischemia; polycystic ovary syndrome; risk; stroke; systematic review
Abstract:
... Background and objective: The last systematic review on the health consequences of child and adolescent obesity found little evidence on consequences for adult health. The present study aimed to summarize evidence on the long-term impact of child and adolescent obesity for premature mortality and physical morbidity in adulthood. Methods: Systematic review with evidence searched from January 2002 t ...
DOI:
10.1038/ijo.2010.222
PubMed:
20975725

50. Low Concentrations of Selenium and Zinc in Nails are Associated with Childhood Asthma

Author:
Maria Fernanda Hornos Carneiro; Claudia Ramos Rhoden; Sérgio Luis Amantéa; Fernando Barbosa Jr
Source:
Biological trace element research 2011 v.144 no.1-3 pp. 244-252
ISSN:
0163-4984
Subject:
manganese; questionnaires; cobalt; copper; zinc; selenium; children; mass spectrometry; asthma; patients; minerals; childhood; Brazil
Abstract:
... The purpose of this study was to investigate possible associations between Zn, Se, Cu, Mn, and Co concentrations in nails and asthma in a young population from a Southern Brazil city. Additionally, correlations between these chemical elements among asthmatic and non-asthmatic children were evaluated. Before nail collection (n = 165), children were asked to complete the International Study of Asthm ...
DOI:
10.1007/s12011-011-9080-3
PubMed:
21607705