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1.  Relationship of ejaculate quality and selected biochemical parameters of blood in cockerels of three laying lines      

Author:
L. Jarinkovičová; L. Máchal; J. Máchal; R. Filipčík; E. Tůmová; R. Horský
Source:
Czech Journal of Animal Science v.57 no.8 pp. 370-376
ISSN:
1212-1819
Subject:
Plymouth Rock; Rhode Island Red; aviaries; blood glucose; blood plasma; calcium; cholesterol; creatinine; glucose; magnesium; phenotypic correlation; phosphorus; sperm concentration; sperm motility; spermatozoa; tail
Abstract:
...  Ejaculates and blood plasma were sampled from cocks of three laying lines: Barred Plymouth Rock (BPR), Sussex Light (SU), and Rhode Island Red (RIR). Ejaculates and blood plasma were sampled four times during the laying period of hens. The following ejaculate parameters were determined: sperm motility, concentrations of sperm cells, ejaculate volume. Sperm morphology was examined. In the blo ...
DOI:
10.17221/6272-cjas

2. (R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture

Author:
Jiancheng Zhang; Li Ma; Yaeko Hashimoto; Xiayun Wan; Jiajing Shan; Youge Qu; Kenji Hashimoto
Source:
Life sciences 2021 v.284 pp. 119882
ISSN:
0024-3205
Subject:
adults; alanine transaminase; aspartate transaminase; body temperature; cecum; creatinine; drugs; inflammation; interleukin-10; interleukin-17; lungs; models; surgery; survival rate
Abstract:
... Sepsis is a life-threatening organ dysfunction syndrome arising from infection-induced uncontrolled systemic inflammatory responses. Patients surviving severe sepsis also exhibit increased mortality due to enhanced vulnerability to infections. In this study, we examined whether (R)-ketamine could prevent against lethal sepsis-induced systemic inflammation and inflammatory organ injury.Septic model ...
DOI:
10.1016/j.lfs.2021.119882

3. (−)-Epicatechin administration protects kidneys against modifications induced by short-term l-NAME treatment in rats

Author:
Paula D. Prince; Cesar G. Fraga; Monica Galleano
Source:
Food & function 2020 v.11 no.1 pp. 318-327
ISSN:
2042-650X
Subject:
beverages; bioavailability; creatinine; diet; kidneys; males; malondialdehyde; oxidative stress; protective effect; rats; renal function; superoxide anion; urea; water
Abstract:
... The aim of this work was to evaluate the protective effects of (−)-epicatechin on the kidneys of NO-deprived rats. Male Sprague Dawley rats were divided into three groups: control (C), receiving water and standard diet; l-NAME (L), receiving a solution of N(ω)-nitro-l-arginine methyl ester (l-NAME) (360 mg l⁻¹ in water) as a beverage and standard diet; and l-NAME-(−)-epicatechin (LE), receiving l- ...
DOI:
10.1039/c9fo02234a

4. 10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats

Author:
Gehad M. Elnagar; Mohamed M. Elseweidy; Nesreen M.I.M. Elkomy; Naif A. Al-Gabri; Mohamed Shawky
Source:
Life sciences 2021 v.279 pp. 119673
ISSN:
0024-3205
Subject:
alcohol abuse; alcohol drinking; alcoholic hepatitis; alcohols; animal models; antioxidants; apoptosis; blood; body weight; caspase-3; catalase; creatinine; cytochrome P-450; endoplasmic reticulum; endoplasmic reticulum stress; glutathione; histopathology; kidney diseases; kidneys; mortality; necrosis; neoplasms; oxidative stress; renal function; superoxide dismutase; transcription factor NF-kappa B; urea; urea nitrogen; uric acid
Abstract:
... Chronic alcoholism induces kidney injury (KI), leading to increased mortality in alcoholic hepatitis patients. Endoplasmic reticulum stress (ER) represents the main initiator of kidney diseases and alcoholic nephropathy.We used alcoholic nephropathy rat model followed by 10-dehydrogingerdione (10-DHGD) intake as potential modulator. This is to focus on ER/oxidative stress/inflammatory and apoptoti ...
DOI:
10.1016/j.lfs.2021.119673

5. 10-y survival in patients who underwent coronary artery bypass grafting surgery in Tehran Heart Center-Coronary Outcome Measurement Study: The powerful predicting ability of the dietary inflammatory index and dietary antioxidant quality

Author:
Mahdieh Abbasalizad Farhangi; Fardin Moradi; Mahdi Najafi; Mohammad Asghari Jafarabadi
Source:
Nutrition 2019 v.63-64 pp. 22-28
ISSN:
0899-9007
Subject:
C-reactive protein; National Cholesterol Education Program; adults; albumins; analysis of variance; antioxidant activity; blood; blood glucose; blood lipids; cohort studies; coronary artery disease; coronary vessels; creatinine; diabetes; diastolic blood pressure; food frequency questionnaires; glucose; heart; hematocrit; high density lipoprotein cholesterol; interleukins; low density lipoprotein cholesterol; males; mortality; myocardial infarction; nutrition assessment; patients; polymerase chain reaction; prediction; reactive oxygen species; restriction fragment length polymorphism; surgery; systolic blood pressure; tumor necrosis factor-alpha; urea nitrogen; Iran
Abstract:
... There is a higher rate of mortality from cardiovascular disease (CVD) in Iran and the mortality rate increases even after coronary artery bypass grafting (CABG). The aim of this study was to evaluate the association between mortality and survival in patients 10 y after CABG, using the dietary inflammatory index (DII) and dietary antioxidant indices.In the current prospective cohort study, 450 pati ...
DOI:
10.1016/j.nut.2019.01.011

6. 137 Effects of the tropical climate on the reference ranges of serum biochemistry in athletic horses

Author:
F.G.F. Padilha; G.B. Meriade; A.M.R. Ferreira
Source:
Journal of equine veterinary science 2021 v.100 pp. 103600
ISSN:
0737-0806
Subject:
alanine transaminase; albumins; anticoagulants; aspartate transaminase; blood chemistry; blood serum; calcium; castration; clinical examination; creatine kinase; creatinine; data analysis; exercise; gamma-glutamyltransferase; horses; humidity; jugular vein; lameness; normal distribution; spectrophotometers; sports; tropics; urea; veterinary medicine
Abstract:
... The purpose of this study was to establish the reference ranges of serum biochemistry parameters of Brazilian Sport Horses undergoing training in a tropical climate. Eighty-nine Brazilian Sport Horses (4 to 11 years; castrated males and females) that were training and competing for equestrian disciplines (showjumping, dressage and eventing) in a tropical climate were selected for this study. All h ...
DOI:
10.1016/j.jevs.2021.103600

7. 14C-Ethion residues in soybean seeds: metabolic pathway, effect of processing, bioavailability, toxicity and protective action of artichoke leaf powder towards rats

Author:
Hassan Abdel-Gawad; Hamdy Taha; Reda Abdel-Hameed; Bahira Hegazi
Source:
Toxicological and environmental chemistry 2013 v.95 no.2 pp. 288-303
ISSN:
1029-0486
Subject:
alanine transaminase; albumins; alkaline phosphatase; artichokes; aspartate transaminase; bioavailability; biochemical pathways; blood proteins; catalase; cholesterol; cholinesterase; chromatography; creatinine; ethion; feces; glutathione transferase; leaves; metabolites; rats; seeds; soybean oil; soybeans; topical application; toxicity; triacylglycerols; urea; urine; very low density lipoprotein
Abstract:
... The metabolic fate of ethion labeled with ¹⁴C-at the ethyl ester groups in soybean seeds following topical application to leaves was studied. Chromatographic analysis of soybean oil revealed the presence of the parent compound together with four metabolites which were identified as ethion monooxon, ethion dioxon, O-ethyl phosphorothioate and O,O-diethyl phosphorothioate. The effect of processing o ...
DOI:
10.1080/02772248.2012.758728

8. 167 Improving the reproductive performance of beef cattle following multivalent viral-bacteria vaccination and mineral supplementation

Author:
G. Decuadro-Hansen; R. Silva; B. Lima; J. Lima; L. Durel; E. Silva; G. Macedo
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 210-211
ISSN:
1031-3613
Subject:
Campylobacter fetus subsp. fetus; Leptospira; Nellore; adjuvants; aluminum hydroxide; antibodies; beef cattle; biotypes; blood serum; body condition; bovine viral diarrhea; breeding season; calcium; cattle production; cobalt; copper; cows; creatinine; farmers; fetus; grazing; herds; immunostimulants; inactivated vaccines; infectious bovine rhinotracheitis; intramuscular injection; iodine; least squares; magnesium chloride; minerals; phosphates; phosphorus; potassium chloride; pregnancy rate; profitability; reproductive disorders; reproductive performance; selenium; seroprevalence; sodium; sodium selenite; subcutaneous injection; tropics; ultrasonics; vaccination; zinc
Abstract:
... In beef cattle production under pasture-based tropical conditions, the minerals most likely to be lacking are Ca, P, Na, Co, Cu, I, Se, and Zn, all of which are required for optimal growth and reproduction. Phosphorous deficiency, in particular, is a major problem for grazing cattle in many tropical regions. On the other hand, reproductive infectious diseases are the greatest threat to the product ...
DOI:
10.1071/RDv32n2Ab167

9. 1H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus)

Author:
Hua-Dong Xu; Jun-Song Wang; Ming-Hui Li; Yan Liu; Ting Chen; Ai-Qun Jia
Source:
Aquatic toxicology 2015 v.159 pp. 69-80
ISSN:
0166-445X
Subject:
Carassius auratus; amino acids; aquatic plants; blood serum; brain; butachlor; creatinine; discriminant analysis; ecotoxicology; edema; energy metabolism; glutathione peroxidase; goldfish; histopathology; kidneys; lactate dehydrogenase; least squares; liver; metabolomics; methane; neurotransmitters; nuclear magnetic resonance spectroscopy; oxidative stress; risk assessment; tissues; toxicity
Abstract:
... Butachlor, one of the most widely used herbicides in agriculture, has been reported with high ecotoxicity to aquatic plants and animals. In this study, a 1H NMR based metabolomics approach combined with histopathological examination and biochemical assays was applied to comprehensively investigate the toxic effects of butachlor on four important organs (gill, brain, liver and kidney) of goldfish ( ...
DOI:
10.1016/j.aquatox.2014.11.020

10. 1H NMR based pharmacometabolomics analysis of metabolic phenotype on predicting metabolism characteristics of losartan in healthy volunteers

Author:
Chenjie He; Yongbin Liu; Yicheng Wang; Jie Tang; Zhirong Tan; Xi Li; Yao Chen; Yuanfei Huang; Xiaoping Chen; Dongsheng Ouyang; Honghao Zhou; Jingbo Peng
Source:
Journal of chromatography 2018 v.1095 pp. 15-23
ISSN:
1570-0232
Subject:
biomarkers; blood; citrates; clinical trials; creatine; creatinine; drugs; gluconeogenesis; glycolysis; lactic acid; least squares; lipid metabolism; lipids; liquid chromatography; males; mass spectrometry; metabolites; models; nuclear magnetic resonance spectroscopy; oral administration; pharmacokinetics; phenotype; phosphorylcholine; prediction; serine; threonine
Abstract:
... Inter-individual variability in drug metabolism and disposition is common in both preclinical and clinical researches. Losartan and its active metabolite EXP3174 present a high degree of inter-individual differences in blood concentrations that affect drug efficacy and side effect. Pharmacometabolomics has been increasingly applied on predicting the drug responses by analyzing the differences in m ...
DOI:
10.1016/j.jchromb.2018.07.016

11. 1H NMR metabolic profiling of the cryopreserved spermatozoa of the wild endangered Persian sturgeon (Acipenser persicus) with the use of beta-cyclodextrin as an external cryoprotectant

Author:
Ruhollah Rahimi; Hamid Farahmand; Alireza Mirvaghefi; Gholamreza Rafiee; Amirreza Abed-Elmdoust
Source:
Fish physiology and biochemistry 2019 v.45 no.3 pp. 1029-1040
ISSN:
0920-1742
Subject:
Acipenser persicus; acetates; analysis of variance; beta-cyclodextrin; biochemical pathways; carnitine; creatine; creatinine; cryopreservation; cryoprotectants; endangered species; genetic resources; glucose; lactic acid; liquid nitrogen; metabolites; metabolomics; nitrogen oxides; nuclear magnetic resonance spectroscopy; phosphates; semen; semen extenders; sperm quality; straw; trimethylamine; vapors
Abstract:
... Persian sturgeon (Acipenser persicus) is an endangered species and genetic resource banking such as gametes and embryo preservation could be one of the most pursued conservation approaches. In this study, deleterious effects of the traditional cryopreservation technique and the effect of different doses of 2-hydroxypropyl-beta-cyclodextrin (HβCD) on thawed spermatozoa quality (motility duration an ...
DOI:
10.1007/s10695-019-00615-8

12. 1H NMR-based metabolic fingerprinting of urine metabolites after consumption of lingonberries (Vaccinium vitis-idaea) with a high-fat meal

Author:
Henna-Maria Lehtonen; Anni Lindstedt; Riikka Järvinen; Jari Sinkkonen; Gonçalo Graça; Matti Viitanen; Heikki Kallio; Ana M. Gil
Source:
Food chemistry 2013 v.138 no.2-3 pp. 982-990
ISSN:
0308-8146
Subject:
Vaccinium vitis-idaea; acids; clinical trials; creatinine; dimethylamine; hippuric acid; humans; metabolism; metabolites; metabolomics; multivariate analysis; nuclear magnetic resonance spectroscopy; powders; rapeseed meal; small fruits; urine
Abstract:
... The use of NMR metabolomics in clinical trials is growing; however, reports of postprandial experiments in humans are scarce. The present study investigated whether consumption of lingonberries as a supplement to an oil-rich meal modifies the postprandial fingerprints of human urine. Urine samples were analysed by 1H NMR, and untargeted multivariate analysis was applied to the data for comprehensi ...
DOI:
10.1016/j.foodchem.2012.10.081

13. 1H NMR-based metabolomics profiling and taste of stewed pork-hock in soy sauce

Author:
Yi Yang; Daodong Pan; Yangying Sun; Ying Wang; Feng Xu; Jinxuan Cao
Source:
Food research international 2019 v.121 pp. 658-665
ISSN:
0963-9969
Subject:
acetates; amino acids; creatine; creatinine; fumarates; meat products; metabolome; metabolomics; multivariate analysis; nuclear magnetic resonance spectroscopy; nucleic acids; sales; secondary metabolites; sensory evaluation; soy sauce; sucrose; taste; China
Abstract:
... Stewed pork-hock in soy sauce is a representative meat product in China. Its taste quality is highly related to primary and secondary metabolites. This study researched the effects of stewing points (0, 30, 60 and 90 min) on the metabolites profile variation of stewed pork-hock in soy sauce by using 1H NMR spectroscopy with multivariate data analysis. The metabolome consisted of 25 metabolites, in ...
DOI:
10.1016/j.foodres.2018.12.035

14. 1H NMR-based metabonomic study on the effects of Epimedium on glucocorticoid-induced osteoporosis

Author:
Sina Pan; Ali Chen; Zhihui Han; Yaling Wang; Xin Lu; Yongxia Yang
Source:
Journal of chromatography 2016 v.1038 pp. 118-126
ISSN:
1570-0232
Subject:
Epimedium; urine; chromatography; creatinine; dexamethasone; oral administration; glucocorticoids; lactic acid; intestinal microorganisms; multivariate analysis; metabolomics; phospholipids; citrates; metabolism; energy; blood serum; taurine; osteoporosis; rats; nuclear magnetic resonance spectroscopy; creatine; biochemical pathways; Oriental traditional medicine
Abstract:
... Glucocorticoids are widely used in clinical practice for the treatment of many immune-mediated and inflammatory diseases, and glucocorticoid-induced osteoporosis (GIO) is the most common type of secondary osteoporosis. Epimedium is one of the most commonly used traditional Chinese medicines for treating osteoporosis. In the present study, we systematically analysed the metabonomic characteristics ...
DOI:
10.1016/j.jchromb.2016.10.015

15. 1H NMR-based urinary metabonomic study of the antidiabetic effects of Rubus Suavissimus S. Lee in STZ-induced T1DM rats

Author:
Zhiheng Su; Xue Ling; Kewei Ji; Huimin Huang; Xi Liu; Chunli Yin; Hongjia Zhu; Yue Guo; Yiyi Mo; Yating Lu; Yonghong Liang; Hua Zheng
Source:
Journal of chromatography 2020 v.1158 pp. 122347
ISSN:
1570-0232
Subject:
Oriental traditional medicine; Rubus suavissimus; acetates; allantoin; animal models; chromatography; citrates; creatinine; gluconeogenesis; glycemic effect; glycolysis; hyperglycemia; insulin-dependent diabetes mellitus; lactic acid; leaves; metabolites; metabolomics; patients; pyruvic acid; rats; shrubs; succinic acid; therapeutics; tricarboxylic acid cycle
Abstract:
... Long-term hyperglycemia associated with diabetes mellitus (DM) causes damage to various organs and tissues, including the eyes, kidneys, heart, blood vessels and nerves. Rubus Suavissimus S. Lee (RS), a shrub whose leaves are used in traditional Chinese medicine (TCM), has been shown to exert hypoglycemic effects in DM patients. However, the underlying mechanism is unclear. This was investigated i ...
DOI:
10.1016/j.jchromb.2020.122347

16. 1H NMR‐based metabolomics approach to assess toxicity of bunker a heavy oil to freshwater carp, Cyprinus carpio

Author:
Emiko Kokushi; Seiichi Uno; Tomotaka Harada; Jiro Koyama
Source:
Environmental toxicology 2012 v.27 no.7 pp. 404-414
ISSN:
1520-4081
Subject:
Cyprinus carpio; blood; carp; creatinine; diet; dietary exposure; freshwater; glutamine; glycerol; hemoglobin; histidine; isoleucine; leucine; liver; metabolites; metabolomics; methionine; nuclear magnetic resonance spectroscopy; oxygen; pollutants; proline; renal function; statistical analysis; toxicity; valine
Abstract:
... Using a 1H NMR metabolomics approach, the effects of dietary exposure of bunker A heavy oil (0.01, 0.1, 1, and 5% in diet) on freshwater carp, Cyprinus carpio, were examined. Statistical analysis by PCA score plots showed that the amount of metabolites in exposure groups 0.1, 1, and 5% differed from those in the control group. Although no discernible effects on metabolites were noted in the 0.1% e ...
DOI:
10.1002/tox.20653
PubMed:
20882592

17. 1H-NMR analysis of the human urinary metabolome in response to an 18-month multi-component exercise program and calcium–vitamin-D3 supplementation in older men

Author:
John R. Sheedy; Paul R. Gooley; Amsha Nahid; Dedreia L. Tull; Malcolm J. McConville; Sonja Kukuljan; Caryl A. Nowson; Robin M. Daly; Peter R. Ebeling
Source:
Applied Physiology, Nutrition, and Metabolism 2014 v.39 no.11 pp. 1294-1304
ISSN:
1715-5320
Subject:
adenosine triphosphate; biomarkers; bone density; bone metabolism; calcium; choline; creatinine; exercise; fortified foods; humans; hypoxanthine; lean body mass; men; metabolism; metabolites; metabolome; metabolomics; milk consumption; monitoring; muscle strength; muscles; nuclear magnetic resonance spectroscopy; patients; randomized clinical trials; urinalysis; urine
Abstract:
... The musculoskeletal benefits of calcium and vitamin-D₃ supplementation and exercise have been extensively studied, but the effect on metabolism remains contentious. Urine samples were analyzed by ¹H-NMR spectroscopy from participants recruited for an 18-month, randomized controlled trial of a multi-component exercise program and calcium and vitamin-D₃ fortified milk consumption. It was shown previ ...
DOI:
10.1139/apnm-2014-0060

18. 1H-NMR-based metabolomics reveals the biomarker panel and molecular mechanism of hepatocellular carcinoma progression

Author:
Ke-xin Wang; Guan-hua Du; Xue-mei Qin; Li Gao
Source:
Analytical and bioanalytical chemistry 2022 v.414 no.4 pp. 1525-1537
ISSN:
1618-2642
Subject:
analytical chemistry; biomarkers; choline; creatinine; early diagnosis; hepatoma; metabolism; metabolites; metabolomics; nuclear magnetic resonance spectroscopy; putrescine; taurine
Abstract:
... Hepatocellular carcinoma (HCC) is one of the most extensive and most deadly cancers in the world. Biomarkers for early diagnosis of HCC are still lacking, and noninvasive and effective biomarkers are urgently needed. Metabolomics is committed to studying the changes of metabolites under stimulation, and provides a new approach for discovery of potential biomarkers. In the current work, ¹H nuclear ...
DOI:
10.1007/s00216-021-03768-9

19. 1H‐NMR‐based water‐soluble low molecular weight compound characterization and fatty acid composition of boiled Wuding chicken during processing

Author:
Zhichao Xiao; Yuting Luo; Guiying Wang; Changrong Ge; Guanghong Zhou; Wangang Zhang; Guozhou Liao
Source:
Journal of the science of food and agriculture 2019 v.99 no.1 pp. 429-435
ISSN:
0022-5142
Subject:
acetates; anserine; boiling; breast meat; chicken meat; creatine; creatinine; deep fat frying; fatty acids; flavor; gas chromatography-mass spectrometry; glucose; lactic acid; metabolome; molecular weight; multivariate analysis; nuclear magnetic resonance spectroscopy; processing stages; taurine; variance; washing; water solubility
Abstract:
... BACKGROUND: Boiled Wuding chicken was produced using whole chicken by washing, boiling 1 h with salt, deep frying, and boiling 2 h. The effect of the process on the water‐soluble low molecular weight (WLOM) compound profiles of products was characterized using proton nuclear magnetic resonance spectroscopy, and the fatty acid composition of products was analyzed using gas chromatography–mass spect ...
DOI:
10.1002/jsfa.9204

20. 2,3,4,5-Tetrakis(3′,4′-dihydroxylphenyl)thiophene: A New Matrix for the Selective Analysis of Low Molecular Weight Amines and Direct Determination of Creatinine in Urine by MALDI-TOF MS

Author:
Chen Suming; Chen Li; Wang Jianing; Hou Jian; He Qing; Liu Jian’an; Wang Jiyun; Xiong Shaoxiang; Yang Guoqiang; Nie Zongxiu
Source:
Analytical chemistry 2012 v.84 no.23 pp. 10291-10297
ISSN:
1520-6882
Subject:
allantoin; alloxan; amines; cost effectiveness; creatinine; desorption; humans; ionization; metabolites; molecular weight; quantitative analysis; tandem mass spectrometry; thiophene; urine
Abstract:
... Small organic matrixes are still the most commonly used ones in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) because of their advantages of high sensitivity, convenience, and cost-effectiveness. However, due to the matrix interference in the low mass region, the direct analysis of low molecular weight amines in complex surroundings with conventional organic matrixes rem ...
DOI:
10.1021/ac3021278

21. 204 Blood Analysis of Cas9-Expressing Cattle

Author:
S.-Y. Yum; S.-J. Lee; S.-E. Hahn; C.-I. Lee; H.-S. Kim; H.-J. Kim; Y.-K. Jin; W.-J. Choi; J.-H. Lee; W.-S. Lee; G. Jang
Source:
Reproduction, fertility, and development 2018 v.30 no.1 pp. 242-243
ISSN:
1031-3613
Subject:
aspartate transaminase; blood sampling; body temperature; calves; creatinine; erythrocytes; females; gene deletion; gene editing; germ cells; health information; health status; hematologic tests; hemoglobin; in vitro fertilization; ingestion; jugular vein; lymphocytes; males; mice; neutrophils; transfection; transgenic animals
Abstract:
... The CRISPR/Cas9 system has proved to be a powerful tool for knockout and knock-in in various species. When 2 components—Cas9 and single guide (sg)RNA—are delivered into cells or embryos, the events of gene editing occur. Because Cas9 is essential for gene editing in the CRISPR/Cas9 system, some studies have reported the production of Cas9-expressing animals, such as mice, which could be used to in ...
DOI:
10.1071/RDv30n1Ab203

22. 24-Week β-alanine ingestion does not affect muscle taurine or clinical blood parameters in healthy males

Author:
Bryan Saunders; Mariana Franchi; Luana Farias de Oliveira; Vinicius da Eira Silva; Rafael Pires da Silva; Vitor de Salles Painelli; Luiz Augusto Riani Costa; Craig Sale; Roger Charles Harris; Hamilton Roschel; Guilherme Giannini Artioli; Bruno Gualano
Source:
European journal of nutrition 2020 v.59 no.1 pp. 57-65
ISSN:
1436-6207
Subject:
adverse effects; alanine transaminase; albumins; alkaline phosphatase; aspartate transaminase; athletes; beta-alanine; biopsy; blood; blood composition; blood sampling; creatine kinase; creatinine; globulins; glomerular filtration rate; high performance liquid chromatography; lactate dehydrogenase; males; maltodextrins; muscles; placebos; protein intake; taurine
Abstract:
... PURPOSE: To investigate the effects of chronic beta-alanine (BA) supplementation on muscle taurine content, blood clinical markers and sensory side-effects. METHODS: Twenty-five healthy male participants (age 27 ± 4 years, height 1.75 ± 0.09 m, body mass 78.9 ± 11.7 kg) were supplemented with 6.4 g day⁻¹ of sustained-release BA (N = 16; CarnoSyn™, NAI, USA) or placebo (PL; N = 9; maltodextrin) for ...
DOI:
10.1007/s00394-018-1881-0

23. 24-h Urine Collection: A Relevant Tool in CKD Nutrition Evaluation

Author:
Moustafa Abdel-Nabey; Camille Saint-Jacques; Jean-Jacques Boffa; Vincent Frochot; Marine Livrozet; Michel Daudon; Martin Flamant; Emmanuel Letavernier; Jean-Philippe Haymann
Source:
Nutrients 2020 v.12 no.9 pp. -
ISSN:
2072-6643
Subject:
administrative management; anemia; compliance; creatinine; diet; excretion; glomerular filtration rate; hyperparathyroidism; kidney diseases; patients; prevalence; protein intake; sodium; urinalysis; urine; volume
Abstract:
... Dietary management is a cornerstone of Chronic Kidney Disease (CKD) monitoring, and dietary surveys often difficult to perform. We studied in a CKD patient cohort with two years follow-up, whether validated 24-h urine ionogram would be a relevant tool for diet evaluation and compliance. We included 404 non-dialysis CKD patients, with three evaluations, including repeated measurements of fractional ...
DOI:
10.3390/nu12092615

24. 24-h variations of blood serum metabolites in high yielding dairy cows and calves

Author:
Hussein Awad Hussein; Jan-Peter Thurmann; Rudolf Staufenbiel
Source:
BMC veterinary research 2020 v.16 no.1 pp. 327
ISSN:
1746-6148
Subject:
age; albumins; bilirubin; blood sampling; blood serum; calves; cholesterol; classification; creatinine; dairy cows; dairy herds; free fatty acids; glucose; health status; hematologic tests; herd health; lactation stage; risk; testing; urea; veterinary medicine
Abstract:
... BACKGROUND: Blood profile testing is commonly used to monitor herd health status, diagnose disorders, and predict the risk of diseases in cows and calves, with subsequent optimization the production of dairy herds. By understanding the physiological ranges of serum metabolites relative to age, lactation stage, and the sampling time in healthy cows and calves, the dairy practitioners can accurately ...
DOI:
10.1186/s12917-020-02551-9

25. 25-Hydroxycholecalciferol Concentration Is Associated with Protein Loss and Serum Albumin Level during the Acute Phase of Burn Injury

Author:
Andrzej Krajewski; Krzysztof Piorun; Dominika Maciejewska-Markiewicz; Marta Markowska; Karolina Skonieczna-Żydecka; Ewa Stachowska; Zofia Polakowska; Maciej Mazurek; Małgorzata Szczuko
Source:
Nutrients 2020 v.12 no.9 pp. -
ISSN:
2072-6643
Subject:
25-hydroxycholecalciferol; C-reactive protein; alanine transaminase; aspartate transaminase; body mass index; burns (injuries); cell proliferation; correlation; creatinine; homeostasis; interleukin-6; population; protein content; protein depletion; risk; serum albumin; surface area
Abstract:
... Background: Burned patients have an increased need for vitamin D supply related to the maintenance of calcium–phosphate homeostasis and the regulation of cell proliferation/differentiation. This study aimed to analyze the concentration of 25-hydroxycholecalciferol and its relationship with severe condition after burn injury. Methods: 126 patients were enrolled in the study. Patients were qualified ...
DOI:
10.3390/nu12092780

26. 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Author:
Jeeyoun Jung; Woo Yeong Park; Yun Jin Kim; Mikyung Kim; Misun Choe; Kyubok Jin; Ji Hae Seo; Eunyoung Ha
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
3-hydroxybutyric acid; albumins; autophagy; blood glucose; blood serum; cages; creatinine; diabetic nephropathy; energy expenditure; glucose; histology; hyperglycemia; kidneys; noninsulin-dependent diabetes mellitus; obesity; oxidative stress; phenotype; phosphorylation; quantitative analysis; reactive oxygen species; urea nitrogen; urine
Abstract:
... Studies report beneficial effects of 3-hydroxybutyrate (3-OHB) on the treatment of type 2 diabetes and obesity, but the effects of 3-OHB on diabetic nephropathy have not been elucidated. This study was designed to investigate the efficacy and mechanism of 3-OHB against progression of diabetic nephropathy (DN). Mice (db/db) were fed normal chow, high-fat, or ketogenic diets (KD) containing precurso ...
DOI:
10.3390/antiox11020381

27. 4-HIL mitigates type-2 diabetic complications through inhibiting inflammation and Nrf2 mediated oxidative stress in rats

Author:
Rupali Singh; Karan Singh Yadav; Ramanand Prajapati; Sharad Sharma; Srikanta Kumar Rath; Tadigoppula Narender; Madhav Nilakanth Mugale
Source:
Phytomedicine plus 2022 v.2 no.1 pp. 100141
ISSN:
2667-0313
Subject:
Trigonella foenum-graecum; animal models; antioxidants; blood serum; catalase; creatinine; eosin; gene expression; genes; glutathione; glycemic control; glycohemoglobin; histopathology; hyperglycemia; inflammation; insulin; insulin receptors; males; mechanism of action; metabolic syndrome; noninsulin-dependent diabetes mellitus; oral administration; oxidative stress; protective effect; rats; superoxide dismutase; triacylglycerols; urea nitrogen; vascular endothelial growth factors
Abstract:
... Hyperglycemia induced diabetic complications as well as dysfunction of multiple organs is closely related to the increased inflammation and oxidative stress (OS). 4-hydroxyisoleucine (4-HIL), a major constituent of Trigonella foenum-graecum L. shown to have anti-diabetic effects. However, its potential mechanism against diabetic complications in the model of metabolic syndrome have not yet been ch ...
DOI:
10.1016/j.phyplu.2021.100141

28. 4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels

Author:
Xu Li; Guang-Guo Ying; Jian-Liang Zhao; Zhi-Feng Chen; Hua-Jie Lai; Hao-Chang Su
Source:
Environment international 2013 v.52 pp. 81-86
ISSN:
0160-4120
Subject:
bisphenol A; bottled water; bottles; ceramics; children; creatinine; detection limit; drinking; females; gas chromatography-mass spectrometry; humans; ionization; males; regression analysis; students; tap water; urine; China
Abstract:
... 4-Nonylphenol (4-NP), bisphenol-A (BPA) and triclosan (TCS) are three industrial chemicals used widely in daily products. This study investigated 4-NP, BPA and TCS levels in urine samples of 287 children and students aged from 3 to 24years old in Guangzhou, China. Total (free and conjugated) amounts of 4-NP, BPA and TCS in the urine samples were detected using gas chromatography–mass spectrometry ...
DOI:
10.1016/j.envint.2011.03.026

29. 4-Nonyphenol induced apoptosis and DNA damage in the African catfish Clarias gariepinus, the antioxidant role of Cydonia oblonga

Author:
Alaa El-Din H. Sayed; Heba S. Hamed
Source:
Ecotoxicology and environmental safety 2017 pp. -
ISSN:
0147-6513
Subject:
aspartate transaminase; DNA damage; lipid peroxidation; creatinine; quinces; blood chemistry; biomarkers; alanine transaminase; glucose; poisoning; apoptosis; albumins; NADP-glucose-6-phosphate dehydrogenase; superoxide dismutase; Clarias gariepinus; toxicity; enzyme activity; antioxidants; leaf extracts; liver; DNA fragmentation; Cydonia oblonga; catalase; uric acid; erythrocytes; cholesterol; urea; catfish; protein content; globulins; alkaline phosphatase
Abstract:
... The present study was planned to assess the toxic effects of sublethal concentration (0.1 mgl−1) 4-nonylphenol (4-NP) on serum biochemical parameters, liver lipid peroxidation (LPO) and the antioxidant enzymes of the African catfish Clarias gariepinus for 14 days and the ability of the quince leaf extract to alleviate the effects of (4-NP) on C. gariepinus. Fish were categorized into four groups: ...
DOI:
10.1016/j.ecoenv.2017.05.013

30. 5-aminolaevulinic acid (ALA), enhances heme oxygenase (HO)-1 expression and attenuates tubulointerstitial fibrosis and renal apoptosis in chronic cyclosporine nephropathy

Author:
Chi Liu; Ping Zhu; Masayuki Fujino; Yoshitaka Isaka; Hidenori Ito; Kiwamu Takahashi; Motowo Nakajima; Tohru Tanaka; Jian Zhuang; Xiao-Kang Li
Source:
Biochemical and biophysical research communications 2019 v.508 no.2 pp. 583-589
ISSN:
0006-291X
Subject:
apoptosis; atrophy; blood serum; creatinine; cyclosporine; fibrosis; gene expression; heme; heme oxygenase (biliverdin-producing); histology; immunologic diseases; inducible nitric oxide synthase; inflammation; interleukin-6; iron; kidney diseases; kidneys; messenger RNA; mice; nephrotoxicity; olive oil; oxidative stress; protective effect; therapeutics; transforming growth factor beta 1; tumor necrosis factor-alpha; urea nitrogen
Abstract:
... Cyclosporine-A (CsA) is an immunosuppressant indicated for various immunological diseases; however, it can induce chronic kidney injury. Oxidative stress and apoptosis play a crucial role in CsA-induced nephrotoxicity. The present study evaluated the protective effect of combining 5-aminolaevulinic acid with iron (5-ALA/SFC), a precursor of heme synthesis, to enhance HO-1 activity against CsA-indu ...
DOI:
10.1016/j.bbrc.2018.11.175

31. 57 Non-targeted metabolomic profiles within the uterine milieu of porcine pregnancies containing populations of uniform or diverse spherical, ovoid, or tubular conceptuses during initiation of embryo elongation

Author:
J. Miles; E. Wright-Johnson; S. Walsh; C. Corey; L. Yao; L. Rempel; A. Pannier
Source:
Reproduction, fertility, and development 2019 v.31 no.1 pp. 154
ISSN:
1031-3613
Subject:
analysis of variance; conceptus; creatinine; crossbreds; embryo (animal); embryonic mortality; estrus; gas chromatography-mass spectrometry; gilts; metabolites; pregnancy; principal component analysis; serine; spectral analysis; tryptophan; ultra-performance liquid chromatography; uric acid
Abstract:
... Alterations in the signalling of critical molecular factors within the uterine milieu result in deficiencies in embryo elongation, leading directly to embryonic loss as well as delayed elongation. The objective of this study was to identify metabolites within the uterine environment from populations of uniform and diverse porcine conceptuses as they transition between spherical, ovoid, and tubular ...
DOI:
10.1071/RDv31n1Ab57

32. 7-Hydroxycoumarin protects against cisplatin-induced acute kidney injury by inhibiting necroptosis and promoting Sox9-mediated tubular epithelial cell proliferation

Author:
Wei-Feng Wu; Jia-Nan Wang; Zeng Li; Biao Wei; Juan Jin; Li Gao; Hai-Di Li; Jun Li; Hai-Yong Chen; Xiao-Ming Meng
Source:
Phytomedicine 2020 v.69 pp. 153202
ISSN:
0944-7113
Subject:
acute kidney injury; adverse effects; antineoplastic activity; blood serum; cell proliferation; cisplatin; cortex; creatinine; cyclins; drug therapy; epithelial cells; herbs; in vitro studies; intraperitoneal injection; kidneys; males; mice; necroptosis; neoplasms; nephrotoxicity; renal function; renoprotective effect; staining; umbelliferones; urea nitrogen
Abstract:
... 7-Hydroxycoumarin (7-HC), also known as umbelliferon, is commonly found in Chinese herbs (e.g. Eucommiae Cortex, Prunellae Spica, Radix Angelicae Biseratae). Previous laboratory studies have indicated that 7-HC has anti-inflammatory, anti-oxidative, and anti-tumor effects. Cisplatin is a widely used chemotherapeutic agent for cancer. Nephrotoxicity is one of the limiting side effects of cisplatin ...
DOI:
10.1016/j.phymed.2020.153202

33. 8-Hydroxy-2-deoxyguanosine levels and heart failure: A systematic review and meta-analysis of the literature

Author:
A. Di Minno; L. Turnu; B. Porro; I. Squellerio; V. Cavalca; E. Tremoli; M.N.D. Di Minno
Source:
Nutrition, metabolism, and cardiovascular diseases 2017 v.27 no.3 pp. 201-208
ISSN:
0939-4753
Subject:
DNA; biomarkers; blood sampling; confidence interval; creatinine; databases; etiology; heart failure; meta-analysis; metabolism; models; patients; prospective studies; systematic review; urine
Abstract:
... The generation of reactive oxygen species (ROS) plays an important role in the etiology of several pathological conditions. High levels of 8-hydroxy-2-deoxyguanosine (8-OHdG), a biomarker of oxidative damage of DNA, have been found in patients with heart failure (HF). We performed a meta-analysis of the literature to investigate the association between 8-OHdG levels and HF.A systematic search was ...
DOI:
10.1016/j.numecd.2016.10.009

34. 8-Hydroxyguanosine as a possible RNA oxidative modification marker in urine from colorectal cancer patients: Evaluation by ultra performance liquid chromatography-tandem mass spectrometry

Author:
Cheng Guo; Qin Chen; Jiani Chen; Jiekai Yu; Yiqiu Hu; Suzhan Zhang; Shu Zheng
Source:
Journal of chromatography 2020 v.1136 pp. 121931
ISSN:
1570-0232
Subject:
RNA; biomarkers; colorectal neoplasms; creatinine; detection limit; disease detection; guanosine; humans; ionization; isotope dilution technique; oxidative stress; patients; screening; solid phase extraction; tandem mass spectrometry; ultra-performance liquid chromatography; urine; volunteers
Abstract:
... Oxidative RNA damage has been found to be associated with a variety of diseases, and 8-hydroxyguanosine (8-OHG) is a typical marker of oxidative modification of RNA. This guanosine modification is an emerging biomarker for disease detection and determination of 8-OHG in human urine is favored because it is noninvasive to patients. However, due to its poor ionization efficiency in mass spectrometry ...
DOI:
10.1016/j.jchromb.2019.121931

35. Lactobacillus plantarum TWK10 Supplementation Improves Exercise Performance and Increases Muscle Mass in Mice

Author:
Yi-Ming Chen; Li Wei; Yen-Shuo Chiu; Yi-Ju Hsu; Tsung-Yu Tsai; Ming-Fu Wang; Chi-Chang Huang
Source:
Nutrients 2016 v.8 no.4 pp. -
ISSN:
2072-6643
Subject:
Lactobacillus plantarum; albumins; ammonia; athletic performance; blood serum; body weight; creatine kinase; creatinine; energy; exercise; glucose; health promotion; intestinal microorganisms; lactic acid; males; mice; muscle tissues; muscles; oral administration; probiotics; swimming; triacylglycerols; urea nitrogen
Abstract:
... Lactobacillus plantarum (L. plantarum) is a well-known probiotic among the ingested-microorganism probiotics (i.e., ingested microorganisms associated with beneficial effects for the host). However, few studies have examined the effects of L. plantarum TWK10 (LP10) supplementation on exercise performance, physical fatigue, and gut microbial profile. Male Institute of Cancer Research (ICR) strain m ...
DOI:
10.3390/nu8040205
PubMed:
27070637
PubMed Central:
PMC4848674

36. Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress

Author:
Amel M. Soliman; Shreen Desouky; Mohamed Marzouk; Amany A. Sayed
Source:
Nutrients 2016 v.8 no.5 pp. -
ISSN:
2072-6643
Subject:
Origanum majorana; antioxidant activity; blood; body weight; catalase; cisplatin; creatinine; drug therapy; free radical scavengers; glutathione; males; malondialdehyde; neoplasms; nephrotoxicity; nitric oxide; oxidative stress; plant extracts; rats; superoxide dismutase; urea; urea nitrogen; uric acid
Abstract:
... Despite the fact that cisplatin is an important anticancer drug, its clinical utilization is limited by nephrotoxicity during long term medication. Combined cisplatin chemotherapy with plant extracts can diminish toxicity and enhance the antitumor efficacy of the drug. This study evaluated the effect of Originum majorana ethanolic extract (OMEE) on cisplatin-induced nephrotoxicity. Eighteen male r ...
DOI:
10.3390/nu8050264
PubMed:
27164131
PubMed Central:
PMC4882677

37. Psoralea corylifolia L. Seed Extract Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis and Apoptosis in Streptozotocin-Induced Diabetic Mice

Author:
Eunhui Seo; Hwansu Kang; Yoon Sin Oh; Hee-Sook Jun
Source:
Nutrients 2017 v.9 no.8 pp. -
ISSN:
2072-6643
Subject:
Cullen corylifolium; animal disease models; apoptosis; cell viability; collagen; creatinine; diabetic nephropathy; fibronectins; fibrosis; gene expression; gene expression regulation; genes; genetic markers; herbal medicines; kidneys; mice; oral administration; protective effect; psoralen; seed extracts; streptozotocin; transforming growth factor beta 1; urine
Abstract:
... The Psoralea corylifolia L. seed (PCS) is a widely used herbal medicine, but its possible effect against diabetic nephropathy has not been studied. To investigate the anti-nephropathic effect of PCS extracts, we performed experiments using a diabetic mouse model and high glucose-treated mesangial cells. Streptozotocin (STZ)-induced diabetic mice were orally administered PCS extract for 8 weeks (50 ...
DOI:
10.3390/nu9080828
PubMed:
28767064
PubMed Central:
PMC5579621

38. Dendropanax morbifera Protects against Renal Fibrosis in Streptozotocin-Induced Diabetic Rats

Author:
Richa Sachan; Amit Kundu; Prasanta Dey; Ji Yeon Son; Kyeong Seok Kim; Da Eun Lee; Hae Ri Kim; Jae Hyeon Park; Su Hyun Lee; Jung-Hwan Kim; Shugeng Cao; Byung Mu Lee; Jong Hwan Kwak; Hyung Sik Kim
Source:
Antioxidants 2020 v.9 no.1 pp. -
ISSN:
2076-3921
Subject:
Dendropanax morbifer; beverages; blood serum; creatinine; cytokines; diabetic nephropathy; excretion; fibrosis; histopathology; inflammation; isozymes; kidneys; metformin; muscles; oxidative stress; pancreas; pyruvate kinase; selenium; streptozotocin; tissue weight; urea nitrogen; weight loss; China; Korean Peninsula
Abstract:
... The aquatic extract of Dendropanax morbifera (DP) is typically consumed as a beverage in Korea and China and is also used in various traditional medicines. However, the functional role of DP on diabetes-induced renal fibrosis is unclear. Here, the protective effects of DP extract against diabetes-induced renal fibrosis were evaluated. Streptozotocin (STZ, 60 mg/kg) was injected intraperiton ...
DOI:
10.3390/antiox9010084

39. Dianthus superbus Improves Glomerular Fibrosis and Renal Dysfunction in Diabetic Nephropathy Model

Author:
Jung Joo Yoon; Ji Hun Park; Hye Jin Kim; Hong-Guang Jin; Hye Yoom Kim; You Mee Ahn; Youn Chul Kim; Ho Sub Lee; Yun Jung Lee; Dae Gill Kang
Source:
Nutrients 2019 v.11 no.3 pp. -
ISSN:
2072-6643
Subject:
C-reactive protein; Dianthus superbus; albumins; angiotensin II; animal disease models; anti-inflammatory agents; basement membrane; biomarkers; blood glucose; cell adhesion; chemokine CCL2; collagen; contraceptives; creatinine; diabetic nephropathy; excretion; fibrosis; glomerulonephritis; homeostasis; humans; inflammation; insulin; insulin resistance; intercellular adhesion molecule-1; intercellular spaces; kidneys; mice; protective effect; staining; therapeutics; traditional medicine; transcription factor NF-kappa B; transforming growth factor beta
Abstract:
... Glomerular fibrosis is caused by an accumulation of intercellular spaces containing mesangial matrix proteins through either diffused or nodular changes. Dianthus superbus has been used in traditional medicine as a diuretic, a contraceptive, and an anti-inflammatory agent. The aim of this study was to investigate the effects of Dianthus superbus-EtOAc soluble fraction (DS-EA) on glomerular fibrosi ...
DOI:
10.3390/nu11030553
PubMed:
30841605
PubMed Central:
PMC6471502

40. Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

Author:
Weizhe Zhang; Jingang Hou; Xiaotong Yan; Jing Leng; Rongyan Li; Jing Zhang; Jingjing Xing; Chen Chen; Zi Wang; Wei Li
Source:
Nutrients 2018 v.10 no.9 pp. -
ISSN:
2072-6643
Subject:
Platycodon grandiflorus; adverse effects; animal models; apoptosis; blood serum; caspases; cisplatin; creatinine; dose response; drug therapy; histopathology; inducible nitric oxide synthase; inflammation; interleukin-1beta; kidneys; mice; neoplasms; nephrotoxicity; phosphorylation; prostaglandin synthase; protective effect; roots; saponins; signal transduction; tissues; transcription factor NF-kappa B; tumor necrosis factor-alpha; urea nitrogen
Abstract:
... Although cisplatin is a potent chemotherapeutic agent against cancers, its clinical application is seriously limited by its severe side effects of nephrotoxicity. Previous studies reported that saponins isolated from the roots of Platycodon grandiflorum (PGS) exerted protective effects in various animal models of renal injury, with no confirmation on cisplatin-induced injury. This study was design ...
DOI:
10.3390/nu10091328
PubMed:
30235825
PubMed Central:
PMC6164643

41. Spirulina platensis Reduced Oxidative Damage Induced by Chlorpyrifos Toxicity in Nile Tilapia (Oreochromis niloticus)

Author:
Mohamed M. Abdel-Daim; Mahmoud A.O. Dawood; Mohamed Elbadawy; Lotfi Aleya; Saad Alkahtani
Source:
Animals 2020 v.10 no.3 pp. -
ISSN:
2076-2615
Subject:
Arthrospira platensis; Oreochromis niloticus; alanine transaminase; albumins; alkaline phosphatase; antioxidant enzymes; aspartate transaminase; blood serum; catalase; chlorpyrifos; cholesterol; creatinine; diet; liver; malondialdehyde; protein content; superoxide dismutase; toxicity; urea
Abstract:
... Due to the numerous pharmacological impacts of Spirulina platensis (SP), the effects of SP on the oxidative status of Nile tilapia farmed under chlorpyrifos (CPF) ambient toxicity were considered in this study. Fish (60 ± 6.1 g) was randomly stocked in five groups where the SP free diet was fed to the control group while the second one was fed 1% SP without CPF exposure. Additionally ...
DOI:
10.3390/ani10030473

42. β-glucan Salecan Improves Exercise Performance and Displays Anti-Fatigue Effects through Regulating Energy Metabolism and Oxidative Stress in Mice

Author:
Xi Xu; Yijian Ding; Yunxia Yang; Yan Gao; Qi Sun; Junhao Liu; Xiao Yang; Junsong Wang; Jianfa Zhang
Source:
Nutrients 2018 v.10 no.7 pp. -
ISSN:
2072-6643
Subject:
adverse effects; alanine transaminase; aspartate transaminase; athletic performance; beta-glucans; biomarkers; blood; blood glucose; creatinine; dietary supplements; drugs; energy metabolism; exercise; forced swimming test; glycogen; lactic acid; males; mice; oxidative stress; signal transduction; swimming; urea nitrogen; water solubility
Abstract:
... Fatigue induced by prolonged exercise not only leads to the decrease of exercise capacity, but also might be the cause of many diseases. In consideration of the side effects of pharmacological drugs, dietary supplements seem to be a better choice to ameliorate exercise-induced fatigue. The present study aimed to investigate the anti-fatigue effect of Salecan, a novel water-soluble β-glucan, d ...
DOI:
10.3390/nu10070858
PubMed:
29970808
PubMed Central:
PMC6073659

43. A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake

Author:
Chwan-Li Shen; Shu Wang; Shengping Yang; Michael D. Tomison; Mehrnaz Abbasi; Lei Hao; Sheyenne Scott; Md Shahjalal Khan; Amanda W. Romero; Carol K. Felton; Huanbiao Mo
Source:
BMC complementary and alternative medicine 2018 v.18 no.1 pp. 198
ISSN:
1472-6882
Subject:
Bixa orellana; alanine transaminase; albumins; alkaline phosphatase; alternative medicine; analysis of variance; aspartate transaminase; bilirubin; blood serum; body composition; bone health; creatinine; delta-tocotrienol; electrolytes; gamma-tocotrienol; globulins; glucose; liver; nutrient intake; olive oil; physical activity; placebos; postmenopause; quality of life; renal function; statistical models; urea nitrogen; women
Abstract:
... BACKGROUND: Evidence suggests that tocotrienols may benefit bone health in osteopenic women. However, their safety in this population has never been investigated. This study was to evaluate the safety of a 12-week supplementation of annato tocotrienol in postmenopausal osteopenic women, along with effects of the supplementation on quality of life, body composition, physical activity, and nutrient ...
DOI:
10.1186/s12906-018-2263-0
PubMed:
29954374
PubMed Central:
PMC6022510

44. A 13-week repeated oral dose toxicity evaluation and a 4-week recovery evaluation of the Sam So Eum (SSE) in male and female rats

Author:
Jong-Hyun Nho; Hyun-Joo Lee; Seon-Yu Lee; Ji-Hun Jang; Beo-Deul Yang; Ji-Hyun Jeong; Guk-Yeo Lee; Hyun-Woo Cho; Jong-Choon Kim; Ho-Kyung Jung
Source:
Journal of ethnopharmacology 2020 v.260 pp. 112988
ISSN:
0378-8741
Subject:
Oriental traditional medicine; Panax ginseng; Perilla frutescens; Peucedanum praeruptorum; adverse effects; anti-allergic agents; blood chemistry; blood serum; creatinine; females; fever; food consumption; hematologic tests; hepatotoxicity; kidneys; males; medicinal plants; no observed adverse effect level; oral administration; plant extracts; rats; urinalysis; vomiting
Abstract:
... Sam So Eum (SSE), used in traditional Korean medicine, has been prescribed for the treatment of various ailments including emesis, and fever for centuries. SSE is known by several different names (Shen Su Yin in traditional Chinese medicine; Jin So In traditional Japanese Kampo medicine). It is a mixture of medicinal plants including Panax ginseng C. A. Mey., Perilla frutescens (L.) Britton, and P ...
DOI:
10.1016/j.jep.2020.112988

45. A 13-week subchronic toxicity study of hinokitiol administered in the diet to F344 rats

Author:
Y.M. Cho; M. Hasumura; S. Takami; T. Imai; M. Hirose; K. Ogawa; A. Nishikawa
Source:
Food and chemical toxicology 2011 v.49 no.8 pp. 1782-1786
ISSN:
0278-6915
Subject:
albumins; cholesterol; creatinine; diet; erythrocytes; females; heart; hematocrit; hemoglobin; liver; males; myocarditis; no observed adverse effect level; rats; subchronic toxicity; toxicology; urea nitrogen; weight gain
Abstract:
... Myocarditis has been reported in male F344 rats given a diet containing hinokitiol (HT). A subchronic toxicity study was here performed to re-evaluate toxic effects of HT in both sexes of F344 rats with dietary administration at concentrations of 0%, 0.02%, 0.07% and 0.2% for 13weeks. Significant reduction of body weight gain was noted in 0.2% males and 0.07% and above females. Significant decreas ...
DOI:
10.1016/j.fct.2011.04.027

46. A 43 kD protein from the leaves of the herb Cajanus indicus L. modulates doxorubicin induced nephrotoxicity via MAPKs and both mitochondria dependent and independent pathways

Author:
Sankhadeep Pal; Parames C. Sil
Source:
Biochimie 2012 v.94 no.6 pp. 1356-1367
ISSN:
0300-9084
Subject:
Cajanus cajan; adenosinetriphosphatase; adverse effects; antioxidant activity; apoptosis; blood; body weight; creatinine; cytochrome c; cytosol; doxorubicin; drug therapy; glucose; kidneys; leaves; lipid peroxidation; magnesium; membrane potential; mitochondria; mitochondrial membrane; mitogen-activated protein kinase; neoplasms; nephrotoxicity; oxidative stress; pathophysiology; phosphorylation; potassium; signal transduction; sodium; tumor necrosis factor-alpha; urea nitrogen; uric acid
Abstract:
... Doxorubicin (Dox), a chemotherapeutic drug, is used for the treatment of different types of cancers. Application of this drug has now been made limited because of its several acute and chronic side effects. The aim of this work is to investigate the nephroprotecive role of a 43 kD protein (CI protein) isolated from the leaves of Cajanus indicus L, against Dox-induced oxidative impairment and kidne ...
DOI:
10.1016/j.biochi.2012.03.003

47. A 90-day subchronic gavage toxicity study in Fischer 344 rats with 3-methylfuran

Author:
S. Gill; M. Kavanagh; W. Cherry; C. Bourque; D. Caldwell; G. Wang; G. Bondy
Source:
Food and chemical toxicology 2018 v.111 pp. 341-355
ISSN:
0278-6915
Subject:
T-lymphocytes; adverse effects; alanine; alkaline phosphatase; amylases; aspartate transaminase; atrophy; biomarkers; blood serum; carboxylic ester hydrolases; creatinine; dose response; electrolytes; females; gamma-glutamyltransferase; hematology; hepatotoxicity; histology; histopathology; liver; lowest observed effect level; males; mineralization; models; no observed adverse effect level; proximal tubules; rats; spleen; toxicology; urea nitrogen; uric acid
Abstract:
... A 90-day gavage study was conducted with 0.0, 0.02, 0.075, 0.25, 1.0 and 4.0 mg/kg bw/day dose groups of 3-methylfuran to identify a no-observed adverse effect level for hepatotoxicity and to characterize non-neoplastic effects including changes in gross anatomy, histopathology, clinical biochemistry and hematology. There were significant changes in the serum clinical biochemistry markers related ...
DOI:
10.1016/j.fct.2017.10.055

48. A Canola Oil-Supplemented Diet Prevents Type I Diabetes-Caused Lipotoxicity and Renal Dysfunction in a Rat Model

Author:
Cano-Europa Edgar; Ortiz-Butron Rocio; Camargo Estela Melendez; Esteves-Carmona María Miriam; Oliart-Ros Rosa Maria; Blas-Valdivia Vanessa; Franco-Colin Margarita
Source:
Journal of medicinal food 2016 v.19 no.11 pp. 1041-1047
ISSN:
1557-7600
Subject:
adipose tissue; animal disease models; body weight; canola; canola oil; cholesterol; creatinine; diet; electrolytes; epididymis; free fatty acids; glomerular filtration rate; glucose; insulin-dependent diabetes mellitus; kidneys; lipid peroxidation; lipotoxicity; males; osmolarity; overeating; rats; reactive oxygen species; triacylglycerols
Abstract:
... We investigated the effect of a canola oil-supplemented diet on the metabolic state and diabetic renal function of a type I diabetes experimental model. Male Sprague-Dawley rats were randomly divided into four groups: (1) normoglycemic+chow diet, (2) normoglycemic+a canola oil-supplemented chow diet, (3) diabetic+chow diet, and (4) diabetic+a canola oil-supplemented chow diet. For 15 weeks, animal ...
DOI:
10.1089/jmf.2016.0019

49. A Comparative Study of Rat Urine 1H-NMR Metabolome Changes Presumably Arising from Isoproterenol-Induced Heart Necrosis Versus Clarithromycin-Induced QT Interval Prolongation

Author:
Matthieu Dallons; Manon Delcourt; Corentin Schepkens; Manuel Podrecca; Jean-Marie Colet
Source:
Biology 2020 v.9 no.5 pp. -
ISSN:
2079-7737
Subject:
betaine; biomarkers; blood serum; cardiotoxicity; clarithromycin; clinical trials; comparative study; creatine; creatinine; dimethylamine; drug development; electrocardiography; glucose; heart; histology; isoproterenols; lactate dehydrogenase; markets; metabolome; metabolomics; necrosis; nitrogen oxides; patients; rats; sarcosines; taurine; toxicity; tricarboxylic acid cycle; trimethylamine; urine
Abstract:
... Cardiotoxicity remains a challenging concern both in drug development and in the management of various clinical situations. There are a lot of examples of drugs withdrawn from the market or stopped during clinical trials due to unpredicted cardiac adverse events. Obviously, current conventional methods for cardiotoxicity assessment suffer from a lack of predictivity and sensitivity. Therefore, the ...
DOI:
10.3390/biology9050098

50. A Comparison of A 4% Modified Fluid Gelatin and A 6% Hydroxyethyl Starch on Haemodilution, Colloid Osmotic Pressure, Haemostasis and Renal Parameters in Healthy Ponies

Author:
Z. Gratwick; A. Viljoen; P.C. Page; A. Goddard; G.T. Fosgate; C.H. Lyle
Source:
Equine veterinary journal 2015 v.47 Suppl S48 no. pp. 18-19
ISSN:
0425-1644
Subject:
adverse effects; blood platelet count; blood serum; clinical trials; creatinine; ethics; fibrinogen; funding; gelatin; hematocrit; hemostasis; herds; horses; osmotic pressure; patients; pets; prothrombin; sediments; specific gravity; starch; thromboplastin; urine; veterinary medicine
Abstract:
... REASONS FOR PERFORMING STUDY: Adverse effects on renal health and haemostasis have been documented in human patients administered hydroxyethyl starches (HES). Gelatins could provide useful substitutes for HES should similar adverse effects be identified in horses. OBJECTIVES: To compare the effects of a 4% modified fluid gelatin (MFG) with a 130/0.4 6% tetrastarch (TES) on haemodilution, colloid o ...
DOI:
10.1111/evj.12486_42

51. A Comparison of Daily Rhythm of Creatinine and Creatine Kinase in the Sedentary and Athlete Horse

Author:
Piccione, Giuseppe; Giannetto, Claudia; Fazio, Francesco; Casella, Stefania; Caola, Giovanni
Source:
Journal of equine veterinary science 2009 v.29 no.7 pp. 575-580
ISSN:
0737-0806
Subject:
creatinine; creatine kinase; physical activity; horses; circadian rhythm; horse breeds; athletic performance

52. A Competitive Enzyme-Linked Immunosorbent Assay-like Method for the Measurement of Urinary Hyaluronan

Author:
Hiroshi MAEDA; Hiroshi FUJITA; Yoshiyuki SAKURA; Kyosuke MIYAZAKI; Makoto GOTO
Source:
Bioscience, biotechnology, and biochemistry 1999 v.63 no.5 pp. 892-895
ISSN:
1347-6947
Subject:
biotechnology; creatinine; hyaluronic acid; molecular weight; urine
Abstract:
... A highly sensitive method for measurement of urinary hyaluronan with a minimum molecular mass of 2,000 Da was developed without using HPLC or radioisotopes. This competitive enzyme-linked immunosorbent assay-like method, used competitive binding of free hyaluronan in the sample and biotin-labeled standard hyaluronan to hyaluronan binding protein in solid phase. A total of 150 healthy individuals f ...
DOI:
10.1271/bbb.63.892

53. A Cu–CNF–rGO-functionalized carbon film indicated as a versatile electrode for sensing of biomarkers using electropolymerized recognition elements

Author:
Haider Ali; Nishith Verma
Source:
Journal of materials science 2022 v.57 no.11 pp. 6345-6360
ISSN:
0022-2461
Subject:
biomarkers; carbon; carbon nanofibers; carbonization; cholesterol; copper nanoparticles; creatinine; electrical conductivity; electrochemistry; electrodes; glucose; graphene oxide; methyl orange; methylene blue; phosphates; polymerization; spermine; vapors; voltammetry
Abstract:
... A carbon film functionalized with reduced graphene oxide (rGO) and Cu nanoparticles (NPs)-tipped carbon nanofibers (CNFs) was demonstrated to be a versatile electrode for the efficient electropolymerization of the following monomers: acryl amide, methylene blue, methyl orange, and β-cyclodextrin. These electropolymers were used as the recognition elements for the measurements of glucose, creatinin ...
DOI:
10.1007/s10853-022-07029-7

54. A Descriptive Study of the Fluid Intake, Hydration, and Health Status of Rehabilitation Inpatients without Dysphagia Following Stroke

Author:
Jo Murray; Sebastian Doeltgen; Michelle Miller; Ingrid Scholten
Source:
Journal of nutrition in gerontology and geriatrics 2015 v.34 no.3 pp. 292-304
ISSN:
2155-1200
Subject:
beverages; blood; cohort studies; constipation; creatinine; descriptive studies; dysphagia; elderly; health status; patients; risk; stroke; urea; urea nitrogen; urinary tract diseases; women
Abstract:
... Adequate hydration is important for all people, particularly when hospitalized with illness. Individuals with dysphagia following stroke are considered to be at risk of inadequate fluid intake and, therefore, dehydration, but there is little information about the fluid intake or hydration of individuals without dysphagia poststroke. This cohort study measured the average beverage intake, calculate ...
DOI:
10.1080/21551197.2015.1054573

55. A Double‐blind, Placebo‐controlled, Multicenter, Prospective, Randomized Study of Beraprost Sodium Treatment for Cats with Chronic Kidney Disease

Author:
M. Takenaka; A. Iio; R. Sato; T. Sakamoto; H. Kurumatani; the KT‐140 Clinical Study Group
Source:
Journal of veterinary internal medicine 2018 v.32 no.1 pp. 236-248
ISSN:
0891-6640
Subject:
blood chemistry; blood serum; cats; creatinine; filtration; kidney diseases; placebos; sodium; specific gravity; urine; vomiting
Abstract:
... BACKGROUND: Chronic kidney disease (CKD) is a common progressive and irreversible disease in cats. The efficacy and safety of beraprost sodium (BPS) in cats with CKD have not been evaluated. HYPOTHESIS/OBJECTIVES: To evaluate the efficacy and safety of BPS in the treatment of cats with CKD, as compared to placebo. ANIMALS: Seventy‐four client‐owned cats with naturally occurring CKD. METHODS: Doubl ...
DOI:
10.1111/jvim.14839
PubMed:
29131397
PubMed Central:
PMC5787173

56. A GC/MS-based metabolomic approach for reliable diagnosis of phenylketonuria

Author:
Xiyue Xiong; Xiaoqi Sheng; Dan Liu; Ting Zeng; Ying Peng; Yichao Wang
Source:
Analytical and bioanalytical chemistry 2015 v.407 no.29 pp. 8825-8833
ISSN:
1618-2642
Subject:
amides; blood; carbohydrates; creatinine; derivatization; fatty acids; gas chromatography-mass spectrometry; gene expression regulation; metabolites; metabolomics; models; patients; phenylacetic acid; phenylalanine; phenylketonuria; phenylpyruvic acid; principal component analysis; separation; t-test; temperature; tyrosine
Abstract:
... Although the phenylalanine/tyrosine ratio in blood has been the gold standard for diagnosis of phenylketonuria (PKU), the disadvantages of invasive sample collection and false positive error limited the application of this discriminator in the diagnosis of PKU to some extent. The aim of this study was to develop a new standard with high sensitivity and specificity in a less invasive manner for dia ...
DOI:
10.1007/s00216-015-9041-3

57. A GC–MS-based metabonomic investigation of blood serum from irritable bowel syndrome patients undergoing intervention with acidified milk products

Author:
Simon M. M. Pedersen; Caroline Nebel; Niels Chr. Nielsen; Henrik J. Andersen; Johan Olsson; Magnus Simrén; Lena Öhman; Ulla Svensson; Hanne C. Bertram; Anders Malmendal
Source:
European food research & technology 2011 v.233 no.6 pp. 1013-1021
ISSN:
1438-2377
Subject:
Bifidobacterium animalis; Lactobacillus acidophilus; Lactobacillus paracasei; acidified milk; aspartic acid; blood glucose; blood sampling; blood serum; creatine; creatinine; digestive system diseases; gas chromatography; glutamine; mass spectrometry; metabolomics; multivariate analysis; patients; principal component analysis; probiotics; proline
Abstract:
... In the present study, the use of gas chromatography mass spectrometry (GC–MS)-based metabonomics to characterize blood serum in an intervention study of patients suffering from the common gastrointestinal disorder irritable bowel syndrome (IBS) was investigated. The patients included in the study consumed an acidified milk product with (n = 30) or without probiotics (n = 31) (Lactobacillus p ...
DOI:
10.1007/s00217-011-1599-1

58. A Genome-Wide Association Study for Hypertensive Kidney Disease in Korean Men

Author:
Hye-Rim Kim; Hyun-Seok Jin; Yong-Bin Eom
Source:
Genes 2021 v.12 no.5 pp. -
ISSN:
2073-4425
Subject:
blood; creatinine; diastolic blood pressure; gene expression; genes; genome-wide association study; glomerular filtration rate; hypertension; kidney diseases; linkage disequilibrium; loci; morbidity; mortality; pathogenesis; quantitative traits; systolic blood pressure; urea nitrogen
Abstract:
... Hypertension is one of the major risk factors for chronic kidney disease (CKD), and the coexistence of hypertension and CKD increases morbidity and mortality. Although many genetic factors have been identified separately for hypertension and kidney disease, studies specifically focused on hypertensive kidney disease (HKD) have been rare. Therefore, this study aimed to identify loci or genes associ ...
DOI:
10.3390/genes12050751

59. A HILIC-UHPLC-MS/MS untargeted urinary metabonomics combined with quantitative analysis of five polar biomarkers on osteoporosis rats after oral administration of Gushudan

Author:
Xiao Wu; Yue Huang; Jinghan Sun; Yongqing Wen; Feng Qin; Longshan Zhao; Zhili Xiong
Source:
Journal of Chromatography B 2017 pp. -
ISSN:
1570-0232
Subject:
urine; ionization; tinidazole; creatinine; hypoxanthine; oral administration; betaine; metabolites; biomarkers; energy metabolism; cytosine; amino acid metabolism; metabolomics; taurine; quantitative analysis; monitoring; t-test; hydrophilic interaction chromatography; models; principal component analysis; osteoporosis; rats; lipid metabolism; spectrometers; ultra-performance liquid chromatography
Abstract:
... A HILIC-UHPLC-MS/MS untargeted urinary metabonomic method combined with quantitative analysis of five potential polar biomarkers in rat urine was developed and validated, to further understand the anti-osteoporosis effect of Gushudan(GSD) and its mechanism on prednisolone-induced osteoporosis(OP) rats in this study. The metabolites were separated and identified on Waters BEH HILIC (2.1mm×100mm, 1. ...
DOI:
10.1016/j.jchromb.2017.10.005

60. A High Intake of trans Fatty Acids Has Little Effect on Markers of Inflammation and Oxidative Stress in Humans

Author:
Liesbeth A. Smit; Martijn B. Katan; Anne J. Wanders; Samar Basu; Ingeborg A. Brouwer
Source:
Journal of nutrition 2011 v.141 no.9 pp. 1673-1678
ISSN:
0022-3166
Subject:
C-reactive protein; adults; cardiovascular diseases; chemotaxis; cholesterol; conjugated linoleic acid; creatinine; diet; energy; high density lipoprotein; humans; inflammation; lipid peroxidation; low density lipoprotein; oleic acid; oxidative stress; receptors; risk; trans fatty acids; tumor necrosis factors; urine
Abstract:
... Consumption of industrial trans fatty acids (iTFA) increases LDL cholesterol, decreases HDL cholesterol, and is strongly associated with a higher risk of cardiovascular disease (CVD). However, changes in circulating cholesterol cannot explain the entire effect. Therefore, we studied whether iTFA and conjugated linoleic acid (CLA) affect markers of inflammation and oxidative stress. Sixty-one healt ...
DOI:
10.3945/jn.110.134668
PubMed:
21753062

61. A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker

Author:
Lina Luo; Ragu Ramanathan; Lauren Horlbogen; Sumathy Mathialagan; Chester Costales; Manoli Vourvahis; Christopher L. Holliman; A. David Rodrigues
Source:
Analytical chemistry 2020 v.92 no.14 pp. 9745-9754
ISSN:
1520-6882
Subject:
analytical chemistry; biomarkers; carnitine; cations; chemical species; creatinine; drug interactions; extrusion; humans; hydrophilic interaction chromatography; liver; mass spectrometry; metformin; organic cation transporters; risk; risk assessment; thiamin; toxins
Abstract:
... There is a growing interest in using endogenous compounds as drug transporter biomarkers to facilitate drug–drug interaction (DDI) risk assessment in early phase I clinical trials. Compared to other drug transporters, however, no valid biomarker for hepatic organic cation transporter (OCT) 1 has been described to date. The present work represents the first report of an endogenous compound, isobuty ...
DOI:
10.1021/acs.analchem.0c01144

62. A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease

Author:
Helena U. Zacharias; Michael Altenbuchinger; Ulla T. Schultheiss; Claudia Samol; Fruzsina Kotsis; Inga Poguntke; Peggy Sekula; Jan Krumsiek; Anna Köttgen; Rainer Spang; Peter J. Oefner; Wolfram Gronwald
Source:
Journal of proteome research 2019 v.18 no.4 pp. 1796-1805
ISSN:
1535-3907
Subject:
artificial intelligence; blood plasma; clinical trials; creatinine; decision making; dialysis; equations; glycoproteins; high density lipoprotein; kidney transplant; models; moieties; nuclear magnetic resonance spectroscopy; patients; proteome; renal failure; risk; valine
Abstract:
... Identification of chronic kidney disease patients at risk of progressing to end-stage renal disease (ESRD) is essential for treatment decision-making and clinical trial design. Here, we explored whether proton nuclear magnetic resonance (NMR) spectroscopy of blood plasma improves the currently best performing kidney failure risk equation, the so-called Tangri score. Our study cohort comprised 4640 ...
DOI:
10.1021/acs.jproteome.8b00983

63. A Phase IIb Randomized Controlled Trial Investigating the Effects of Tocotrienol-Rich Vitamin E on Diabetic Kidney Disease

Author:
Yan Yi Koay; Gerald Chen Jie Tan; Sonia Chew Wen Phang; J-Ian Ho; Pei Fen Chuar; Loon Shin Ho; Badariah Ahmad; Khalid Abdul Kadir
Source:
Nutrients 2021 v.13 no.1 pp. -
ISSN:
2072-6643
Subject:
albumins; albuminuria; animals; antioxidants; biomarkers; blood serum; creatinine; diabetes; kidney diseases; placebos; population; renal function; tocotrienols; urine; vascular endothelial growth factor A; Malaysia
Abstract:
... Diabetic kidney disease (DKD) is a debilitating complication of diabetes, which develops in 40% of the diabetic population and is responsible for up to 50% of end-stage renal disease (ESRD). Tocotrienols have shown to be a potent antioxidant, anti-inflammatory, and antifibrotic agent in animal and clinical studies. This study evaluated the effects of 400 mg tocotrienol-rich vitamin E supplementati ...
DOI:
10.3390/nu13010258

64. A Pilot Study on Using Urinary 1-Hydroxypyrene Biomarker for Exposure to PAHs in Beijing

Author:
Zhang, Wenjie; Xu, Dongqun; Zhuang, Guoshun; Ding, Changming; Wang, Guifang; Chang, Junrui; Ren, Gaiying
Source:
Environmental monitoring and assessment 2007 v.131 no.1-3 pp. 387-394
ISSN:
0167-6369
Subject:
biomarkers; creatinine; high performance liquid chromatography; police; polycyclic aromatic hydrocarbons; probability; traffic; China
Abstract:
... To study whether the urinary 1-hydroxypyrene (1-OHP) could be the biomarker of atmospheric PAHs, a small-scale pilot study was carried out on the relation of 1-OHP vs PAHs with the traffic policemen in Beijing of smokers and nonsmokers to be subgroups in both the exposure and control groups. Both the PAHs and 1-OHP were analyzed with high performance liquid chromatography (HPLC). The ambient conce ...
DOI:
10.1007/s10661-006-9484-2

65. A Preliminary Study on Antioxidant Activities of Saffron Petal Extracts in Lambs

Author:
Arash Omidi; Seddighe Rahdari; Mohammad Hassanpour Fard
Source:
Veterinary science development 2014 v.4 no.1 pp. -
ISSN:
2038-9698
Subject:
Crocus sativus; alanine transaminase; albumins; alkaline phosphatase; antioxidant activity; aspartate transaminase; bilirubin; blood sampling; blood serum; body temperature; body weight; cholesterol; corolla; creatinine; globulins; glucose; heart rate; lambs; males; malondialdehyde; protein content; respiratory rate; saffron; thiols; triacylglycerols; urea nitrogen; uric acid; weight control
Abstract:
... This study assessed the effects of hydroalcoholic extract of saffron (Crocus sativus L) petals on male lambs and was aimed at evaluating the antioxidant activity of this extract during a 15-day period. Fourteen male lambs were divided randomly into three treatment groups (n=4 each) and a control group (normal saline; n=2). Saffron petal extract at 500, 1000 and 1500 mg/kg was administered by gavag ...
DOI:
10.4081/vsd.2014.5161

66. A Prospective Study of Iodine Status, Thyroid Function, and Prostate Cancer Risk: Follow-up of the First National Health and Nutrition Examination Survey

Author:
Hoption Cann, S.A.; Qiu, Z.; Van Netten, C.
Source:
Nutrition and cancer 2007 v.58 no.1 pp. 28-34
ISSN:
0163-5581
Subject:
National Health and Nutrition Examination Survey; adults; iodine; nutritional status; thyroid function; prostatic neoplasms; risk assessment; epidemiology; urine; creatinine; dietary minerals; thyroid diseases; temporal variation; disease diagnosis
Abstract:
... Few studies have investigated the association between iodine status, thyroid disease, and cancer risk despite evidence that thyroid function impacts many organs, including the prostate. We investigated iodine status and prostate cancer risk prospectively using data from the NHANES I Epidemiologic Follow-up Study. Participants were stratified into tertiles according to the urinary iodine/creatinine ...
DOI:
10.1080/01635580701307960
PubMed:
17571964

67. A Proton-Pump Inhibitor Modifies the Concentration of Digestion Biomarkers in Healthy Horses

Author:
Stephânia Katurchi Mendes Mélo; Tito Alves Santiago; Thaisa de Lima Duarte; José Mário Girão Abreu; Helena Emília Cavalcanti da Costa Cordeiro Manso; Hélio Cordeiro Manso Filho
Source:
Journal of equine veterinary science 2014 v.34 no.11-12 pp. 1318-1323
ISSN:
0737-0806
Subject:
biomarkers; blood; blood proteins; blood sampling; calcium; cholesterol; creatinine; digestion; fasting; glucose; horses; magnesium; oral administration; phosphorus; protein metabolism; proton pump; stomach ulcers; triacylglycerols; urea; uric acid
Abstract:
... To determine the concentration of various blood biomarkers associated with digestion in healthy horses treated with different doses of omeprazole (OMPZ), four Arabian horses without gastric ulcers were selected and distributed in one factorial with four oral treatments (Control; OMPZBOLUS; OMPZ4mg/kg; OMPZ1mg/kg). Control did not receive any treatment. OMPZBOLUS were given 4 mg/kg of omeprazole in ...
DOI:
10.1016/j.jevs.2014.09.013

68. A Questionnaire-Based Survey on the Long-Term Management of Canine Leishmaniosis by Veterinary Practitioners

Author:
Maria A. Pereira; Rute Santos; Carmen Nóbrega; Cristina Mega; Rita Cruz; Fernando Esteves; Carla Santos; Catarina Coelho; João R. Mesquita; Helena Vala; Gabriela Santos-Gomes
Source:
Animals 2022 v.12 no.6 pp. -
ISSN:
2076-2615
Subject:
Leishmania infantum; allopurinol; antibodies; blood proteins; clinical examination; creatinine; decline; dogs; electrophoresis; indigenous species; leishmaniasis; metropolitan areas; patients; questionnaires; relapse; remission; serology; surveys; urine; Portugal
Abstract:
... Canine Leishmaniosis (CanL) is a chronic and potentially fatal disease. In economically disadvantaged regions, costs associated with long-term patient monitoring may determine that some owners decline veterinary follow-up of their dogs. This online, questionnaire-based survey aimed to assess how Portuguese veterinary practitioners perform long-term patient monitoring and recognize relapses. More t ...
DOI:
10.3390/ani12060731

69. A Randomised Cross-Over Pharmacokinetic Bioavailability Study of Synthetic versus Kiwifruit-Derived Vitamin C

Author:
Anitra C. Carr; Stephanie M. Bozonet; Margreet C. M. Vissers
Source:
Nutrients 2013 v.5 no.11 pp. 4451-4461
ISSN:
2072-6643
Subject:
Actinidia chinensis; ascorbic acid; bioavailability; blood; creatinine; electrochemistry; excretion; experimental design; fasting; flavonoids; high performance liquid chromatography; kiwifruit; males; pharmacokinetics; urine
Abstract:
... Kiwifruit are a rich source of vitamin C and also contain numerous phytochemicals, such as flavonoids, which may influence the bioavailability of kiwifruit-derived vitamin C. The aim of this study was to compare the relative bioavailability of synthetic versus kiwifruit-derived vitamin C using a randomised cross-over pharmacokinetic study design. Nine non-smoking males (aged 18–35 years) received ...
DOI:
10.3390/nu5114451
PubMed:
24284610
PubMed Central:
PMC3847741

70. A Report of a Hepatozoon Canis Infection in a Dog with Transmissible Venereal Tumour

Author:
Namakkal Rajamanickam Senthil; Subramanian Subapriya; Subbaiah Vairamuthu
Source:
Macedonian veterinary review 2015 v.38 no.2 pp. 233-237
ISSN:
1409-7621,1857-7415
Subject:
Hepatozoon canis; albumins; creatinine; dogs; erythrocytes; globulins; hemoglobin; neutrophils; protein content; urea nitrogen
Abstract:
... In the present study, a case of a Hepatozoan canis infection in a dog with a sexually transmissible venereal tumour is reported. Haematological examination revealed marked decrease in haemoglobin, PCV and RBC counts and the blood smear revealed rouleaux formation of RBC, hypochromasia, leptocytes and neutrophilia. Neutrophils were parasitized with both non-nucleated and stained nucleated forms of ...
DOI:
10.14432/j.macvetrev.2015.06.046

71. A Retrospective Study of 1,098 Blood Samples with Anemia from Adult Cats: Frequency, Classification, and Association with Serum Creatinine Concentration

Author:
E. Furman; E. Leidinger; E.H. Hooijberg; N. Bauer; G. Beddies; A. Moritz
Source:
Journal of veterinary internal medicine 2014 v.28 no.5 pp. 1391-1397
ISSN:
0891-6640
Subject:
adults; anemia; blood serum; cats; creatinine; erythrocyte count; erythrocytes; hematocrit; hemoglobin; medicine; retrospective studies
Abstract:
... BACKGROUND: Frequency and classification of anemia in terms of regeneration status and erythrocyte indices are not well described in cats. OBJECTIVE: To determine frequency and regenerative status of anemia in samples from adult cats, to assess the sensitivity and specificity of macrocytosis and hypochromasia for detecting regenerative anemia (RA), and to evaluate the association of anemia with in ...
DOI:
10.1111/jvim.12422
PubMed:
25274437
PubMed Central:
PMC4895589

72. A Retrospective Study of the Medical Status on 63 African Hedgehogs (Atelerix albiventris) at the Taipei Zoo From 2003 to 2011

Author:
Hsieh Pei-Chi; Yu Jane-Fang; Wang Lih-Chiann
Source:
Journal of exotic pet medicine 2015 v.24 no.1 pp. 105-111
ISSN:
1557-5063
Subject:
Atelerix albiventris; adults; alanine transaminase; albumins; alkaline phosphatase; animals; aspartate transaminase; bilirubin; blood serum; creatinine; death; females; inbreeding; longevity; males; retrospective studies; squamous cell carcinoma; trade; zoos; Taiwan; United States
Abstract:
... Inbreeding of African hedgehogs (Atelerix albiventris) is considered a problem as breeders try to meet the demands of the pet trade. Most studies of African hedgehogs are concentrated in the USA. This study investigates and compares the life span and medical conditions of captive African hedgehogs at the Taipei Zoo, Taiwan. The medical records of 63 African hedgehogs at the Taipei Zoo from 2003 to ...
DOI:
10.1053/j.jepm.2014.11.003

73. A Short-term Diet High in Carboxymethyl-lysine (CML) Increases Urinary Excretion but Not Serum CML Levels (P12-012-19)

Author:
Claudia Luevano-Contreras; Rosalia Lopez-Gutierrez; Armando Gomez-Ojeda; Ma Eugenia Garay-Sevilla; Jorge Ramirez-Telles
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
Maillard reaction; absorption; adults; advanced glycation end products; blood serum; creatinine; diet; excretion; fat intake; foods; health effects assessments; randomized clinical trials; t-test; urine; washing
Abstract:
... Dietary advanced glycation end products (AGEs) are a group of compounds formed by the Maillard reaction. Carboxymethyl-lysine (CML), a marker of AGEs in foods, may contribute to cardiometabolic diseases. However, CML health effects and its absorption and excretion in healthy individuals remained controversial. For this reason, the aim of this study was to evaluate serum and urinary excretion CML l ...
DOI:
10.1093/cdn/nzz035.P12-012-19

74. A Soy Protein Diet Alters Hepatic Lipid Metabolism Gene Expression and Reduces Serum Lipids and Renal Fibrogenic Cytokines in Rats with Chronic Nephrotic Syndrome

Author:
Tovar, Armando R.; Murguia, Fernanda; Cruz, Cristino; Hernández-Pando, Rogelio; Aguilar-Salinas, Carlos A.; Pedraza-Chaverri, Jose; Correa-Rotter, Ricardo; Torres, Nimbe
Source:
Journal of nutrition 2002 v.132 no.9 pp. 2562-2569
ISSN:
0022-3166
Subject:
binding proteins; blood lipids; casein; creatinine; cytokines; fatty-acid synthase; gene expression; genes; hypercholesterolemia; hypertriglyceridemia; ingestion; insulin; kidneys; lipid metabolism; low density lipoprotein cholesterol; low protein diet; malic enzyme; messenger RNA; nephrotic syndrome; rats; sclerosis; soy protein
Abstract:
... Nephrotic syndrome (NS) is characterized by the presence of proteinuria and hyperlipidemia. However, ingestion of soy protein has a hypolipidemic effect. The present study was designed to determine whether the ingestion of a 20% soy protein diet regulates the expression of hepatic sterol regulatory element binding protein (SREBP)-1, fatty acid synthase (FAS), malic enzyme, β-hydroxy-β-methylglutar ...
PubMed:
12221209

75. A Specific High-Protein Weight Loss Program Does Not Impair Renal Function in Patients Who Are Overweight/Obese

Author:
Anne-Sophie Truche; Sébastien Bailly; Odile Fabre; Rémy Legrand; Philippe Zaoui
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
creatinine; glomerular filtration rate; kidney diseases; overweight; weight loss
Abstract:
... Although high-protein diets appear to be the most efficient way to lose weight, concerns may arise about their innocuity on renal function. The objective of this study is to assess the impact of a weight loss program on renal function. A multicentric cohort-based study was performed using the RNPCFrench national weight loss program. Patients with at least two creatinine measurements at the beginni ...
DOI:
10.3390/nu14020384

76. A Study on Alteration in Serum Biochemical Parameters in Colibacillosis Affected Diarrhoeic Cattle Calves

Author:
T.C. Nayak; A.P. Singh; A. Chahar; Savita; R. Yadav; J.P. Kachhawa; S.R. Gupta
Source:
Indian journal of animal research 2021 v.55 no.11 pp. 1347-1351
ISSN:
0976-0555
Subject:
Escherichia coli; albumins; animal research; animal science; antioxidants; bicarbonates; blood serum; chlorides; creatinine; glucose; oxidants; polymerase chain reaction; potassium; protein content; sodium; urea; India
Abstract:
... The objective of the present study was to evaluate the changes in serum biochemical parameters in colibacillosis affected diarrhoeic cattle calves below one month of age. The study was undertaken at Veterinary Clinical Complex, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner, Rajasthan, India, during the period from September 2018 to March ...
DOI:
10.18805/IJAR.B-4502

77. A Tomato Lycopene Complex Protects the Kidney From Cisplatin-Induced Injury via Affecting Oxidative Stress as Well as Bax, Bcl-2, and HSPs Expression

Author:
Ayhan Dogukan; Mehmet Tuzcu; Can Ali Agca; Hasan Gencoglu; Nurhan Sahin; Muhittin Onderci; İbrahim Hanifi Ozercan; Necip İlhan; Omer Kucuk; Kazim Sahin
Source:
Nutrition and cancer 2011 v.63 no.3 pp. 427-434
ISSN:
1532-7914
Subject:
antioxidants; beta-carotene; blood serum; body weight; cisplatin; creatinine; kidneys; lipid peroxidation; lycopene; malondialdehyde; nephrotoxicity; oxidative stress; protective effect; protein synthesis; rats; tocopherols; tomatoes; urea nitrogen
Abstract:
... Cisplatin-induced nephrotoxicity is related to an increase in oxidative stress in the kidney. Lycopene, a carotenoid found in tomatoes, is a potent dietary antioxidant. In the present study, we investigated the effect of the tomato lycopene complex against cisplatin-induced lipid peroxidation and nephrotoxicity in rats. Male Wistar rats (n = 28, 8 wk old, between 200–215 g) were divided into 4 gro ...
DOI:
10.1080/01635581.2011.535958
PubMed:
21391123

78. A Uremic Goat Model Created by Subtotal Renal Artery Embolization and Gentamicin

Author:
Maaike K. van Gelder; Joost C. de Vries; Sabbir Ahmed; Anneke S. Monninkhof; Gérard A. P. de Kort; Evert-Jan P. A. Vonken; Diënty H. M. Hazenbrink; Koen R. D. Vaessen; Tri Q. Nguyen; Marianne C. Verhaar; Jaap A. Joles; Karin G. F. Gerritsen
Source:
Biology 2021 v.10 no.4 pp. -
ISSN:
2079-7737
Subject:
acute kidney injury; animal models; creatinine; gentamicin; goats; kidneys; phosphates; polyvinyl alcohol; potassium; renal function; urea; uremia
Abstract:
... A large animal model of (end-stage) kidney disease (ESKD) is needed for the preclinical testing of novel renal replacement therapies. This study aimed to create stable uremia via subtotal renal artery embolization in goats and induce a temporary further decline in kidney function by administration of gentamicin. Renal artery embolization was performed in five Dutch white goats by infusing polyviny ...
DOI:
10.3390/biology10040292

79. A Validation Study of Adiponectin rs266729 Gene Variant with Type 2 Diabetes, Obesity, and Metabolic Phenotypes in a Taiwanese Population

Author:
Tun-Jen Hsiao; Eugene Lin
Source:
Biochemical genetics 2016 v.54 no.6 pp. 830-841
ISSN:
0006-2928
Subject:
adiponectin; alanine transaminase; body mass index; cholesterol; collagen; creatinine; diastolic blood pressure; gender; genes; genotyping; glucose; human population; noninsulin-dependent diabetes mellitus; obesity; phenotype; single nucleotide polymorphism; triacylglycerols; waist circumference; Taiwan
Abstract:
... Previous data suggesting that a single nucleotide polymorphism (SNP), rs266729, in the adiponectin C1Q and collagen domain containing (ADIPOQ) gene was associated with type 2 diabetes (T2D) have been inconsistent, especially in Asian populations. In this replication study, we aimed to reassess whether the ADIPOQ rs266729 SNP is associated with T2D, obesity, and T2D/obesity-related metabolic traits ...
DOI:
10.1007/s10528-016-9760-y

80. A benchmark dose analysis for urinary cadmium and type 2 diabetes mellitus

Author:
Peng Shi; Huanchang Yan; Xingjun Fan; Shuhua Xi
Source:
Environmental pollution 2021 v.273 pp. 116519
ISSN:
0269-7491
Subject:
National Health and Nutrition Examination Survey; cadmium; creatinine; data collection; dose response; heavy metals; noninsulin-dependent diabetes mellitus; pollution; risk
Abstract:
... Cadmium (Cd) is a heavy metal referred to as one of the environmental endocrine disruptors. The dose-dependent association between Cd and type 2 diabetes mellitus (T2DM) has been elucidated, but the corresponding threshold has not been established. To evaluate the urinary Cd levels associated with T2DM, we perform a benchmark dose (BMD) analysis based on data from the 1999–2006 National Health and ...
DOI:
10.1016/j.envpol.2021.116519

81. A benzimidazole derivative (RCB15) in vitro induces the alternative energetic metabolism and glycolysis in Taenia crassiceps cysticerci

Author:
Guaraciara de Andrade Picanço; Nayana Ferreira de Lima; Carolina Miguel Fraga; Tatiane Luiza da Costa; Eliana Isac; Javier Ambrosio; Rafael Castillo; Marina Clare Vinaud
Source:
Acta tropica 2017 pp. -
ISSN:
0001-706X
Subject:
3-hydroxybutyric acid; Taenia crassiceps; acetates; acetyl coenzyme A; albendazole; benzimidazole; beta oxidation; creatinine; culture media; cysticerci; cysticercosis; drugs; gluconeogenesis; glucose; glycolysis; high performance liquid chromatography; lactic acid; protein metabolism; pyruvic acid; spectroscopy; urea
Abstract:
... The emergence of resistance to albendazole has encouraged the search for effective alternatives for cysticercosis and other parasitosis treatment. RCB15 is a benzimidazole derivative that may be used against such diseases. The aim of this study was to determine the in vitro effect of RCB15 on the alternative energetic pathways of Taenia crassiceps cysticerci. The cysticerci were in vitro exposed t ...
DOI:
10.1016/j.actatropica.2017.08.022

82. A better diet quality is associated with a reduced likelihood of CKD in older adults

Author:
B. Gopinath; D.C. Harris; V.M. Flood; G. Burlutsky; P. Mitchell
Source:
Nutrition, metabolism, and cardiovascular diseases 2013 v.23 no.10 pp. 937-943
ISSN:
0939-4753
Subject:
Australians; Dietary Guidelines; blood serum; confidence interval; creatinine; elderly; food frequency questionnaires; food intake; glomerular filtration rate; healthy diet; kidney diseases; nutrients; nutritional adequacy; odds ratio
Abstract:
... BACKGROUND AND AIMS: Studies of diet in relation to chronic kidney disease (CKD) have focused on individual nutrients. The relationship between overall patterns of food intake and renal function has not been well explored. We aimed to investigate the associations between diet quality with the prevalence, incidence and progression of CKD in a cohort of older adults. METHODS AND RESULTS: 1952 partic ...
DOI:
10.1016/j.numecd.2012.07.003
PubMed:
22902186

83. A biomarker survey of urinary deoxynivalenol in China: the Shanghai Women's Health Study

Author:
P.C. Turner; B.T. Ji; X.O. Shu; W. Zheng; W.H. Chow; Y.T. Gao; L.J. Hardie
Source:
Food additives & contaminants 2011 v.28 no.9 pp. 1220-1223
ISSN:
1944-0057
Subject:
barley; humans; women; biomarkers; cohort studies; corn; wheat; poisoning; creatinine; Western diets; women's health; esophageal neoplasms; deoxynivalenol; metabolites; United Kingdom; China
Abstract:
... Deoxynivalenol (DON) is a trichothecene mycotoxin found on wheat, maize and barley. In ecological surveys in China, DON and other trichothecenes have been implicated in acute poisoning episodes and linked with the incidence of esophageal cancer. In order to better understand exposure patterns, this pilot survey provided a combined measure of urinary un-metabolised or free DON (fD) and its glucuron ...
DOI:
10.1080/19440049.2011.584070
PubMed:
21774617
PubMed Central:
PMC3171645

84. A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats

Author:
Natália Lôres Lopes; Diefrey Ribeiro Campos; Marília Alves Machado; Mariana Silva Revoredo Alves; Manuela Silva Gomes de Souza; Cristiano Chaves Pessoa da Veiga; Alexandre Merlo; Fábio Barbour Scott; Julio Israel Fernandes
Source:
BMC veterinary research 2019 v.15 no.1 pp. 137
ISSN:
1746-6148
Subject:
cats; corn starch; creatinine; cytokines; gastrointestinal system; hematologic tests; liver; maleates; mixed breeds; monocytes; neutrophils; non-specific protein-tyrosine kinase; pH; placebos; pruritus; specific gravity; toxicity; urine; vomiting
Abstract:
... BACKGROUND: Oclacitinib is a Janus kinase (JAK) 1 enzyme inhibitor and blocks JAK1-dependent cytokines and is used to control pruritus. Studies available in cats are very limited and as there is a potential role for oclacitinib in the control of pruritus in this specie, the aim of this study was to evaluate the safety and clinical effects of oral oclacitinib maleate in healthy cats. RESULTS: Thirt ...
DOI:
10.1186/s12917-019-1893-x
PubMed:
31068210
PubMed Central:
PMC6506962

85. A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings

Author:
Paul Nayim; Armelle T. Mbaveng; Arsene M. Ntyam; Victor Kuete
Source:
BMC complementary medicine and therapies 2020 v.20 no.1 pp. 273
ISSN:
2662-7671
Subject:
Imperata cylindrica; acute oral toxicity; alternative medicine; aspartate transaminase; cholesterol; creatinine; cytotoxicity; females; granulocytes; health status; heart; hemoglobin; histology; histopathology; humans; kidneys; liver; low density lipoprotein; males; methanol; mortality; multiple drug resistance; neoplasm cells; oral administration; root extracts; spices; subchronic exposure; toxicity testing; triacylglycerols; Cameroon
Abstract:
... BACKGROUND: The cytotoxicity of the root’s methanol extract of Imperata cylindrica (ICR). was previously reported in a panel of human cancer cell lines, including multi-drug resistant phenotypes. The aim of this study was to assess the acute and sub-chronic oral toxicity of methanol root extract of Imperata cylindrica. METHODS: The acute toxicity was carried out according to the experimental proto ...
DOI:
10.1186/s12906-020-03064-6

86. A branched arabinoglucan from Angelica sinensis ameliorates diabetic renal damage in rats

Author:
Yi Sui; Wenjuan Liu; Wen Tian; Xiao‐Qiang Li; Wei Cao
Source:
Phytotherapy research 2019 v.33 no.3 pp. 818-831
ISSN:
0951-418X
Subject:
Angelica sinensis; advanced glycation end products; animal disease models; antagonists; blood; creatinine; diabetic nephropathy; inflammation; kidneys; patients; plasmids; proteinuria; rats; signal transduction; small interfering RNA; streptozotocin; transcription factor NF-kappa B; urea nitrogen; viability
Abstract:
... Diabetic nephropathy (DN) is a major complication in long‐standing diabetic patients, and effective therapies are required. In this study, we examined the effects and mechanisms of an arabinoglucan (AG) isolated from Angelica sinensis on DN, which was induced in rats by streptozotocin. The rats were intraperitoneally treated with AG for 8 weeks. Diabetic rats exhibited renal dysfunction, as eviden ...
DOI:
10.1002/ptr.6275

87. A capillary electrochromatography-electron spray ionization-mass spectrometry method for simultaneous analysis of charged and neutral constituents of a hepatocarcinoma cell metabolome

Author:
Kato, Masaru; Onda, Yuko; Sekimoto, Masashi; Degawa, Masakuni; Toyo'oka, Toshimasa
Source:
Journal of chromatography 2009 v.1216 no.47 pp. 8277-8282
ISSN:
0021-9673
Subject:
chromatography; creatinine; electrospray ionization mass spectrometry; formic acid; hepatoma; homocysteine; humans; metabolome; metabolomics; silica
Abstract:
... Although metabolome research is a rapidly expanding field in the postgenomic era, no single method exists for complete analysis of all the constituents of a metabolome. In this study, we developed a metabolome analysis method using a combination of capillary electrochromatography and electrospray ionization-mass spectrometry. The capillary electrochromatography column was prepared by surface modif ...
DOI:
10.1016/j.chroma.2009.06.074

88. A case report of acute renal failure caused by Amanita neoovoidea poisoning in Anhui Province, eastern China

Author:
Hong Wang; Yan Wang; Fei-Fan Shi; Shuo Zhang; Wei-Ting Fang; La-Mei Qi; Nan Wang; Can Huang; Hai-Qin Fang; Hai-Jiao Li
Source:
Toxicon 2020 v.173 pp. 62-67
ISSN:
0041-0101
Subject:
Amanita; acute kidney injury; alanine transaminase; albumins; amanitins; basidiomata; blood; case studies; cholinesterase; creatinine; gastrointestinal system; ingestion; lactate dehydrogenase; liver failure; mushrooms; patients; poisoning; urea nitrogen; uric acid; urine; China
Abstract:
... Amanita neoovoidea (genus Amanita Pers.) poisoning leads to acute renal failure. Here, we present seven case reports of acute renal failure with acute hepatic failure due to ingestion of A. neoovoidea. Clinical manifestations included gastrointestinal symptoms 1–72 h after ingestion; elevation of renal parameters and blood uric acid, blood urea nitrogen, and creatinine levels; a few abnormal hepat ...
DOI:
10.1016/j.toxicon.2019.11.007

89. A case report of bill color aberration in a free-living Eurasian Tree Sparrow (Passer montanus): Morphological and physiological description

Author:
Mo Li; Qian Zhang; Xiaohan Gao; Yanfeng Sun; Jiaxin Cao; He Li; Yuefeng Wu; Dongming Li
Source:
Wilson journal of ornithology 2019 v.131 no.3 pp. 553-560
ISSN:
1559-4491
Subject:
3-hydroxybutyric acid; Passer montanus; alkaline phosphatase; birds; blood glucose; body condition; case studies; color; creatinine; enzyme activity; females; free fatty acids; hematocrit; high density lipoprotein cholesterol; lactate dehydrogenase; low density lipoprotein cholesterol; phenotype; plumage; protein content; protein metabolism; temperature; thermoregulation; triacylglycerols; uric acid; wings
Abstract:
... Color aberration in birds is a common biological phenomenon relative to other vertebrates. To date, a large number of avian species with abnormally colored individuals have been documented. Although evidence has shown that color aberration may co-vary with morphological and physiological traits, little information is available on the variations of morphological and physiological traits of free-liv ...
DOI:
10.1676/18-165

90. A case-control study of arsenic exposure with the risk of primary ovarian insufficiency in women

Author:
Wuye Pan; Xiaoqing Ye; Zheying Zhu; Chunming Li; Jianhong Zhou; Jing Liu
Source:
Environmental science and pollution research international 2020 v.27 no.20 pp. 25220-25229
ISSN:
0944-1344
Subject:
anti-Mullerian hormone; arsenic; blood serum; case-control studies; creatinine; estradiol; females; follicle-stimulating hormone; luteinizing hormone; odds ratio; pollution; research; risk factors; toxicity
Abstract:
... Arsenic, a well-known toxic metalloid, is ubiquitously existed in environment. Arsenic exposure has been associated with female reproductive health. However, a potential association between arsenic exposure and primary ovarian insufficiency (POI) in women has not been recognized yet. In this case-control study, a total of 169 POI cases and 209 healthy controls were recruited to determine urinary c ...
DOI:
10.1007/s11356-020-08806-0

91. A case-control study of urinary levels of iodine, perchlorate and thiocyanate and risk of papillary thyroid cancer

Author:
Lei Zhang; Congrong Fang; Liping Liu; Xin Liu; Sai Fan; Jingguang Li; Yunfeng Zhao; Song Ni; Shaoyan Liu; Yongning Wu
Source:
Environment international 2018 v.120 pp. 388-393
ISSN:
0160-4120
Subject:
atomic absorption spectrometry; case-control studies; confidence interval; creatinine; iodine; logit analysis; odds ratio; perchlorates; risk factors; tandem mass spectrometry; thiocyanates; thyroid neoplasms; ultra-performance liquid chromatography; urine
Abstract:
... The incidence of thyroid cancer has recently increased worldwide. With the exception of radiation exposure, the effects of potential risk factors on thyroid cancer incidence remain controversial.The association between exposure to iodine, perchlorate, and thiocyanate and papillary thyroid cancer (PTC) incidence was evaluated and risk factors were predicted.A pair-matching case-control study was pe ...
DOI:
10.1016/j.envint.2018.08.024

92. A clinical and pathological description of 320 cases of naturally acquired Babesia rossi infection in dogs

Author:
Andrew L. Leisewitz; Amelia Goddard; Sarah Clift; Peter N. Thompson; Jill de Gier; Jessica M.A.J.A.J. Van Engelshoven; Johan P. Schoeman
Source:
Veterinary parasitology 2019 v.271 pp. 22-30
ISSN:
0304-4017
Subject:
Babesia canis subsp. rossi; bilirubin; blood serum; cortisol; creatinine; death; disease severity; dog diseases; dogs; hospitals; hypoglycemia; neutrophils; odds ratio; parasites; pathogenesis; polymerase chain reaction; regression analysis; researchers; thyroid hormones; urea
Abstract:
... Babesia rossi causes the most severe clinical disease in dogs of all the babesia parasites. We included 320 naturally-infected dogs that presented for care at the Onderstepoort Veterinary Academic Hospital between 2006 and 2016. All dogs had mono-infections confirmed by multiplex PCR. The data allowed more accurate clinical classification of the disease and identified parameters that were associat ...
DOI:
10.1016/j.vetpar.2019.06.005

93. A closer look at the health of cats showing urinary house-soiling (periuria): a case-control study

Author:
Daniela Ramos; Archivaldo Reche-Junior; Daniel S Mills; Priscila L Fragoso; Alexandre GT Daniel; Mariana F Freitas; Silvia G Cortopassi; Geni Patricio
Source:
Journal of feline medicine and surgery 2019 v.21 no.8 pp. 772-779
ISSN:
1532-2750
Subject:
animal behavior; bladder; blood; case-control studies; cats; clinical examination; creatinine; cystitis; cystoscopy; females; households; renal calculi; renal failure; ultrasonics; urinalysis; urination; urine
Abstract:
... The aim of this study was to perform a case-control medical evaluation of cats from multi-cat households presenting with inappropriate latrining and spraying behavior. Owners of 18 ‘spraying’ and 23 ‘latrining’ cats with normal control subjects available from the same households were recruited for a case-control study. Otherwise overtly healthy dyads (each dyad consisting of a case cat and a contr ...
DOI:
10.1177/1098612X18801034

94. A colorimetric microwell method using a desktop scanner for biochemical assays

Author:
Camilo de Lelis Medeiros de Morais; Kássio Michell Gomes de Lima
Source:
Talanta 2014 v.126 pp. 145-150
ISSN:
0039-9140
Subject:
automation; blood; cholesterol; color; colorimetry; computers; correlation; creatinine; detection limit; glucose; photometers; prediction; protein content; scanners; triacylglycerols; user interface
Abstract:
... A method for rapid, inexpensive and sensitive simultaneous analysis of glucose, creatinine, triglycerides, total cholesterol and total protein is needed to analyze blood. The proposed method is based on the production of a specific color after reaction. The method was adapted to a 64-microwell plate format, and it uses the transparency scanner feature of a commercially available desktop scanner. E ...
DOI:
10.1016/j.talanta.2014.03.066

95. A comparative assessment of dilution correction methods for spot urinary analyte concentrations in a UK population exposed to arsenic in drinking water

Author:
Daniel R.S. Middleton; Michael J. Watts; David A. Polya
Source:
Environment international 2019 v.130 pp. 104721
ISSN:
0160-4120
Subject:
arsenic; biomarkers; creatinine; data collection; drinking water; environmental exposure; osmolality; specific gravity; urine; United Kingdom
Abstract:
... Spot urinary concentrations of environmental exposure biomarkers require correction for dilution. There is no consensus on the most appropriate method, with creatinine used by default despite lacking theoretical robustness. We comparatively assessed the efficacy of creatinine; specific gravity (SG); osmolality and modifications of all three for dilution correcting urinary arsenic. For 202 particip ...
DOI:
10.1016/j.envint.2019.03.069
PubMed:
31207477
PubMed Central:
PMC6686075

96. A comparative study of chronic kidney disease in dogs and cats: Induction of cyclooxygenases

Author:
Akira Yabuki; Sawane Mitani; Mariko Sawa; Keijiro Mizukami; Makoto Fujiki; Osamu Yamato
Source:
Research in veterinary science 2012 v.93 no.2 pp. 892-897
ISSN:
0034-5288
Subject:
cat diseases; cats; chronic diseases; creatinine; dogs; fibrosis; histopathology; immunohistochemistry; kidneys; prostaglandin synthase; sclerosis
Abstract:
... The present study investigated whether renal cyclooxygenase (COX) induction is associated with the severity of chronic kidney disease (CKD) in dogs and cats. The collected kidneys were examined histopathologically and immunohistochemically. The immunoreactivities of COX-1 and COX-2 were evaluated quantitatively, and the correlations to the plasma creatinine concentrations, glomerular size, glomeru ...
DOI:
10.1016/j.rvsc.2011.12.017
PubMed:
22244709

97. A comparative study of nutrients utilization, alkaline phosphatase activity and creatinine concentration in the serum of sheep and goats fed diets based on olive leaves

Author:
Yáñez-Ruiz, D.R.; Molina-Alcaide, E.
Source:
Journal of animal physiology and animal nutrition 2008 v.92 no.2 pp. 141-148
ISSN:
0931-2439
Subject:
alkaline phosphatase; animal health; barley; blood serum; carbohydrates; copper; creatinine; crude protein; diet; digestibility; digestion; energy; faba beans; goats; leaves; neutral detergent fiber; nitrogen; nutrients; olives; polyethylene glycol; wethers
Abstract:
... The aim of this study was to compare, in goats and wethers, the nutritive utilization of diets including olive leaves (OL) and the possible detrimental effect of that by-product. Three different diets were studied: OL, OL plus polyethylene glycol (PEG) (OLP) and OL supplemented with barley [164 g/kg dry matter (DM)] and faba beans (59 g/kg DM) (OLSUP). Apparent digestibility of nutrients and energ ...
DOI:
10.1111/j.1439-0396.2007.00719.x
PubMed:
18336410

98. A comparison of nutritionally-related blood metabolites among Nguni, Bonsmara and Angus steers raised on sweetveld

Author:
Ndlovu, T.; Chimonyo, M.; Okoh, A.I.; Muchenje, V.; Dzama, K.; Dube, S.; Raats, J.G.
Source:
Veterinary journal 2009 v.179 no.2 pp. 273-281
ISSN:
1090-0233
Subject:
aspartate transaminase; Angus; grazing; beef cattle; seasonal variation; creatinine; phosphorus; serum albumin; pastures; Bonsmara; steers; animal nutrition; blood lipids; air temperature; blood glucose; breed differences; nutritional status; nutritive value; creatine kinase; cholesterol; urea; globulins
Abstract:
... The objective of the study was to determine monthly variations in serum glucose, cholesterol, total protein (TP), urea, albumin, globulin, albumin/globulin ratio, creatinine, aspartate aminotransferase (AST), creatinine kinase (CK), alkaline phosphatase (ALP), calcium, phosphorus and magnesium in Nguni, Bonsmara and Angus beef steers raised on sweetveld. Twenty-five Nguni, 15 Aberdeen Angus and 15 ...
DOI:
10.1016/j.tvjl.2007.09.007
PubMed:
17959398

99. A comparison of the effects of a 4% modified fluid gelatin and a 6% hydroxyethyl starch on haemodilution, colloid osmotic pressure, haemostasis and renal parameters in healthy ponies

Author:
Z. Gratwick; A. Viljoen; P. C. Page; A. Goddard; G. T. Fosgate; C. H. Lyle
Source:
Equine veterinary journal 2017 v.49 no.3 pp. 363-368
ISSN:
0425-1644
Subject:
adverse effects; blood platelet count; blood serum; creatinine; fibrinogen; gelatin; hematocrit; hemostasis; horses; osmotic pressure; patients; prothrombin; sediments; specific gravity; starch; thromboplastin; urine
Abstract:
... REASONS FOR PERFORMING STUDY: Adverse effects on renal health and haemostasis have been documented in human patients administered hydroxyethyl starches (HESs). Gelatins may represent useful substitutes should similar adverse effects be identified in horses. OBJECTIVES: To compare the effects of a 4% modified fluid gelatin (MFG) with a 6% (130/0.4) HES on haemodilution, colloid osmotic pressure (CO ...
DOI:
10.1111/evj.12594

100. A comparison of the physiological status in parasitized roe deer (Capreolus capreolus) from two different populations

Author:
M. Jégo; H. Ferté; J.M. Gaillard; F. Klein; L. Crespin; E. Gilot-Fromont; G. Bourgoin
Source:
Veterinary parasitology 2014 v.205 no.3-4 pp. 717-720
ISSN:
0304-4017
Subject:
Capreolus capreolus; albumins; creatinine; endoparasites; hematocrit; hosts; parasitism; phenotype; physiological response; physiological state
Abstract:
... Studies of the impact of parasites on host performance have mainly focused on body mass, a phenotypic trait that responds relatively slowly to the presence of parasites, and the expectedly faster response of physiological parameters has been mostly overlooked. We filled the gap by measuring the impact of endoparasites on four hematological/biochemical parameters (hematocrit, albumin, creatinine an ...
DOI:
10.1016/j.vetpar.2014.09.016