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in vivo studies; dual-energy X-ray absorptiometry; magnetic resonance imaging; anthropometric measurements; histidine; biomarkers; nitrogen; skeletal muscle; chemical analysis; models; body composition; human health; creatinine; potassium; bioelectrical impedance; computed tomography; metabolites
... Two Bos taurus breeds with known differences in heat tolerance were tested under controlled conditions to evaluate heat tolerance. Romosinuano (Romo) is a tropically adapted breed. Nine Angus (304 ± 7 Kg BW) and nine RO (285 ± 7.5 Kg BW) steers from USDA-ARS, Brooksville, Florida, were transported to the Brody Environmental Center at the University of Missouri. Steers were housed for 14 days at th ...
... Rice culture of a toxigenic strain of Aspergillus ochraceus was fed at a concentration of 25% to weanling pigs for 10 days. The clinicopathological abnormalities reflected renal damage. Activities of lactic dehydrogenase, glutamic-oxaloacetic transaminase and isocitrate dehydrogenase were increased in the urine but not in the serum. Serum concentrations of urea nitrogen and creatinine were high. C ...
... Normal values for a number of blood components of grivet monkeys are reported. Haematological data and values for glucose, cholesterol and urea are similar to those of rhesus monkeys. Activities of alkaline phosphatase (1526 U/l), glutamine oxaloacetate trans-aminase (30·9 U/l), glutamine pyruvate transaminase (13·7 U/l), lactate dehydrogenase (629 U/l), α-hydroxybutyrate dehydrogenase (175 U/l), ...
... A nephropathy with severe tubular atrophy was observed in Beagle dogs after oral administration of K₂HPO₄ for 14 or 38 weeks. We describe the complete lysosomal degradation of atrophying tubular epithelial cells. During two experiments of 14 and 38 weeks duration, respectively, a total of 15 Beagle dogs received 0.8 g K₂HPO₄/kg body weight daily with their food. All dogs were examined clinically a ...
... The concentrations of many components of the cerebrospinal fluid are much lower than in serum. Values for sodium, potassium, calcium and magnesium are similar to those in other primates. Activities of alkaline phosphatase (18·7 U/l), creatine phosphokinase (9·9 U/l), glutamine oxaloacetate transaminase (13·7 U/l), glutamine pyruvate transaminase (9·2 U/l), γ-glutamyl transpeptidase (3·1 U/l), α-hy ...
... The reaction of rats and rabbits to long-term application of acidified drinking water (pH 2·3-2·5) was observed over a 7-months period. The following parameters were studied: growth curves initiated at weaning, haematology, blood glucose, total serum protein, creatinine, inorganic phosphate, sodium, potassium, calcium, alkaline phosphatase, creatinine kinase, serum glutamate oxalacetate transamina ...
... The estimation of endogenous creatinine clearance yields information useful to the renal physiologist without the need to introduce a marker compound. The method has been limited in its application to mammalian species of bodyweight 200 g and above due to the blood sample size required. A modification is described whereby this procedure may be applied to animals of bodyweight as low as 25 g. Use o ...
... 24 h urinary alanine-amino-peptidase (AAP) and gamma-glutamyl transferase (GGT) activities were studied from the 3rd-7th month of life in male Wistar rats. A close relationship was found between AAP and GGT activity, except at the beginning and at the end of this period. At the end there appear 2 subgroups, the larger (70%) showing a strong correlation between AAP and GGT activity and the other (3 ...
... Partial ileal bypass (PIB) surgery is a method for the treatment of familial hypercholesterolaemia in man. Since the rabbit is frequently used as an animal model in experimental studies on PIB, we have investigated the long-term effects of this surgical procedure on the health status of rabbits. Forty-eight weeks after surgery plasma and liver cholesterol levels were decreased by about 40%. The in ...
nuclear magnetic resonance spectroscopy; anthropometric measurements; body water; creatinine; potassium; neutron activation analysis; body fat
Abstract:
... Renewed interest in the assessment of human body composition has stimulated the need for a balanced understanding of available methodologies of estimating fat-free mass and percent body fat. This review summarizes the physical bases and assumptions, decribes applications, and discusses the theoretical and practical limitations of currently available indirect methods. Although standard methods are ...
... Ten 14-week-old calves were fed a diet containing 87.5% NaOH-treated barley, and killed after 29, 65, 71, 117, 140, 179, 314, 338, and 408 days. Eight control calves were fed a diet in which untreated rolled barley was substituted for alkali-treated grain. Calves receiving NaOH-treated barley became polyuric with urine pH ranging from 9.0 to 9.5, and had significantly raised plasma creatinine leve ...
... 25 female sheep of the Texel breed were made hyperglycaemic by administration of alloxan monohydrate (ALX) in early pregnancy and 15 ewes served as controls. Average venous glucose levels (mean ± standard deviation) increased from 3·5 ± 0·2 to 14·0 ± 1·8 mmol/l. All hyperglycaemic sheep were treated with long-acting insulin in doses adjusted individually (0·2-1·0 U/kg per day) to keep glucose leve ...
... Hematologic and serum biochemical tests were used to monitor the health of 3 groups of bison in an experimental study of tuberculosis. Bison were randomly assigned to Mycobacterium bovis-infected, M. bovis -sensitized, and uninfected control groups. Hematologic measurements included total and differential leukocyte counts, hemoglobin (Hb), packed cell volume (PCV), fibrinogen, and plasma proteins. ...
... The effects of dietary aflatoxin (AF) and diacetoxyscirpenol (DAS), singly and in combination, were evaluated in growing crossbred barrows. The experimental design consisted of 4 treatments of 9 barrows each fed diets containing 1) 0 mg AF and 0 mg DAS/kg feed (control), 2) 2.5 mg AF/kg feed, 3) 2.0 mg DAS/kg feed, or 4) 2.5 mg AF + 2.0 mg DAS/kg feed for 28 days (10–14 weeks of age). Production p ...
... Cisplatin (CDDP), an effective chemotherapeutic drug, is toxic to the kidneys. Previous reports suggest that the pretreatment of mice, by injection or by diet, with trace elements that induce kidney metallothionein (MT) prevents the toxicity. This study was designed to determine if pretreatment with subcutaneous oil-emulsion (SCOE) doses of Zn would induce synthesis of kidney MT and prevent CDDP t ...
... SUMMARY: Blood samples were drawn repeatedly from sows to detect quantitative variation in several blood parameters associated with disease resistance, performance or both. Pure Norwegian Landrace (L) sows, crosses between L and Duroc (L*D) and crosses between L and Yorkshire (L*Y) were compared. Blood samples were collected one and three months after farrowing, and repeatability, as well as effec ...
dietary fat; vitamin content; alpha-tocopherol; fat intake; creatinine; phosphorus; women; young adults; beta-carotene; test meals; blood lipids; blood serum; triacylglycerols; lifestyle; vitamin A; ascorbic acid; dietary protein; nutritional status; long term effects; cholesterol; protein intake; food choices; nutrition knowledge
Abstract:
... Five free-living women (ages 23-38 years) who consumed a self-selected diet and five women (ages 23-44 years) residing in a metabolic unit who were fed constant diet were assessed for variation in vitamin and general chemistry indices. Blood was drawn from these women once a month for five months, once a week for five weeks, and once a day for five days to assess analytical and biological variabil ...
... Aqueous nitrosation of creatinine (CRN) yields 5-oxocreatinine 5-oxime (OCNO) and 1-methyl-5-oxohydantoin 5-oxime (MOHO). Nitrosation of OCNO yields MOHO. Because further nitrosation of MOHO yields methylurea, which can be nitrosated to give the carcinogen methylnitrosourea, the CRN to OCNO to MOHO reactions were reinvestigated. On treatment of CRN with six batches of nitrite at pH 1, MOHO yield b ...
... This project studied the effects of processing time and temperature on the formation of MeIQx and DiMeIQx, two of the most common aminoimidazoazasrenes (AIAs) found in food. Each model system containing threonine, glucose, and creatine (2:1:2 molar ratio) was processed for 2 h at a temperature between 125 and 250 degrees C. Neither MeIQx nor DiMeIQx was found at processing temperatures lower than ...
... SUMMARY: Blood plasma levels of the hormones bovine growth hormone (bGH), insulin and insulin-like growth factor 1 (IGF-1) and the metabolites glucose, free fatty acids (FFA), urea, creatine and creatinine in 70 bulls (Fleckvieh, Braunvieh, Grauvieh) kept at four AI stations were measured. Plasma determinations were performed on day 1 with normal feeding (N), day 4 after fast (F), and day 5 (R) af ...
... Troponin T is a cardiac-specific protein forming part of the contractile apparatus of striated muscle, and in humans it is a new, sensitive and highly specific indicator of early myocardial damage in 'at risk' patients. Serum troponin T values were investigated in 7-day-old hypoxia- and hyperoxia-treated and 10-day-old ascitic and debilitated commercial broiler chicks. The results showed that ther ...
... Thirty-eight dry, pregnant Jersey cows were assigned to diet and bST treatment in a 2 x 2 factorial design. During the dry period, half of the cows were fed a normal TMR (0.4% Ca; 0.3 to 0.4% P), and half of the cows were fed a high Ca TMR (1.5 to 1.6% Ca; 0.4 to 0.7% P). The high Ca diets were designed to induce milk fever and were relatively cationic (194 to 293 meq/kg) compared with the normal ...
... Nursing sickness in mink is thought to be precipitated by inadequate salt intake, whether this is due to inadequate salt levels in the diet or inadequate total dietary intake. To test this hypothesis, lactating females raising large litters were given 2 daily intramuscular injections of the loop diuretic furosemide (Lasix, 4 + 4 mg/kg/day) for 2.5 d during the normal weaning period 6 wk after part ...
... Objective: An elevated serum concentration of the metabolite, homocysteine (Hcys): 1) can indicate folate or vitamin B12 deficiency, 2) is an independent risk factor for vascular disease. The metabolite, methylmalonic acid (MMA), is elevated in deficiency of vitamin B12, but not folate. The purpose of this study was to determine the effect of self-selected vitamin supplementation and other variabl ...
... In the period from November 1995 to April 1996 we have collected 120 samples of 24-h-urine from volunteers of the „Brandenburger Ernährungs- und Krebsstudie“. 108 persons — without iodine supplementation — showed an average iodine excretion about 99 µg I/g creatinine, and the median value showed 94.2. Only 45.4 % of the samples indicated a sufficient iodine supply. In 43.5 % an iodine deficiency g ...
... A previous experiment using rats indicated that dietary nickel (Ni), folic acid, and their interaction affected variables associated with one-carbon metabolism. That study used diets that produced only mild folate deficiency. Thus, an experiment was performed to determine the effect of a severe folate deficiency on nickel deprivation in rats. A 2x2 factorially arranged experiment used groups of si ...
... SUMMARY: Six normal-conformation and six double-muscled Belgian White-blue bulls were involved in a 2 × 2 × 2 factorial experiment to investigate the effect of genotype (normal versus double-muscled), body weight (400 versus 600 kg) and dietary crude protein (135 versus 165 g per kg dry matter) on voluntary feed intake, digestion and its consequences on the nutritive value, metabolites in blood an ...
... Rhubarb extract was given orally to rats with diabetic nephropathy induced by subtotal nephrectomy and injection of streptozotocin. As a result, high blood and urinary glucose levels, which were conspicuous in similarly treated rats that were not given rhubarb extract, were ameliorated. Furthermore, improvement of hyperlipidaemia, and accelerated excretion of urinary urea nitrogen and creatinine w ...
... Alfalfa was harvested as silage or hay and fed in two 12-wk trials with a 4 X 4 Latin square design that used 12 (trial 1) or 24 (trial 2) multiparous lactating cows (4 ruminally cannulated cows per trial). Diets contained (dry matter basis) 75 or 50% alfalfa plus 24 or 40% high moisture corn (trial 1) or 50% alfalfa, 44 or 41% high moisture corn, with (3%) or without fish meal (trial 2). Experime ...
... The diagnostic accuracy of the urinary cortisol:creatinine ratio (CCR), with the cortisol being measured by ELISA, was evaluated by subjecting data from 18 dogs with and 20 dogs without hyperadrenocorticism to recelver operating characteristic (ROC) curve analysis. The area under the ROC curve (W 0–93, SEw 0–044) was much higher than 045, indicating that the CCR did distinguish between dogs with a ...
... We investigated the goiter prevalence and the urinary iodine excretion of 2 109 young people between 10 and 18 years in the district of Mecklengurg-Vorpommern, Germany in 1995/96. The thyroid volume was determined by ultrasound (7,5 MHz), the iodine excretion by a modified cer-arsenit method. The daily iodine excretion as related to the body surface area and the age related creatinine excretion pe ...
... The acute toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D), a herbicide, was studied in chicks dosed with 100, 300, 500, or 600 mg 2,4-D/kg BW, by the oral route. Clinical, laboratory, and histopathological methods were used as indicators of toxicity. After acute exposure, the herbicide decreased motor activity and induced muscular weakness and motor incoordination; decreased weight gain; increa ...