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- Camerlengo, Francesco; Sestili, Francesco; Silvestri, Marco; Colaprico, Giuseppe; Margiotta, Benedetta; Ruggeri, Roberto; Lupi, Roberta; Masci, Stefania; Lafiandra, Domenico
- BMC plant biology 2017 v.17 no.1 pp. 248
- gliadin, etc ; amino acid sequences; celiac disease; cultivars; epitopes; gene expression; introgression; loci; multigene family; mutation; pleiotropy; toxicity; wheat; wheat gluten; Show all 14 Subjects
- ... BACKGROUND: Among wheat gluten proteins, the α-type gliadins are the major responsible for celiac disease, an autoimmune disorder that affects about 1% of the world population. In fact, these proteins contain several toxic and immunogenic epitopes that trigger the onset of the disease. The α-type gliadins are a multigene family, encoded by genes located at the complex Gli-2 loci. RESULTS: Here, th ...
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