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- Li, Kai Kai; Zhou, Xuelin; Wong, Hing Lok; Ng, Chun Fai; Fu, Wei Ming; Leung, Ping Chung; Peng, Guiyuan; Ko, Chun Hay
- Journal of ethnopharmacology 2016 v.192 pp. 192-200
- Gleditsia sinensis, etc ; anti-inflammatory activity; necrosis; Gleditsia triacanthos; reactive oxygen species; prostaglandins; mechanism of action; dose response; macrophages; gene expression; messenger RNA; tumor necrosis factor-alpha; rats; antioxidant activity; nitric oxide; inflammation; interleukin-6; edema; prostaglandin synthase; Oriental traditional medicine; Show all 20 Subjects
- ... Zao-Jiao-Ci (ZJC), as the spine of Chinese Honey locust (Gleditsia sinensis Lam.), is traditionally used as Chinese medicine to reduce inflammation.The present study aimed to investigate an anti-inflammatory effect of ZJC aqueous extract both in vitro and in vivo, as well as its underlying mechanisms.Anti-inflammatory effect of ZJC aqueous extract was evaluated by using carrageenan-induced paw ede ...
- Yi, Jin-Mu; Park, Jong-Shik; Oh, Se-Mi; Lee, Jun; Kim, Jinhee; Oh, Dal-Seok; Bang, Ok-Sun; Kim, No Soo
- BMC complementary and alternative medicine 2012 v.12 no.1 pp. 243
- Gleditsia sinensis, etc ; alternative medicine; angiogenesis; antineoplastic agents; cell movement; cytotoxicity; dose response; endothelins; ethanol; human umbilical vein endothelial cells; medicine; mice; obesity; plant spines; proteins; proteomics; thrombosis; Show all 17 Subjects
- ... BACKGROUND: Gleditsia sinensis thorns have been widely used in traditional Korean medicine for the treatment of several diseases, including obesity, thrombosis, and tumor-related diseases. The aim of the study is to determine the antiangiogenic effect of Gleditsia sinensis thorns in vitro and in vivo in a bid to evaluate its potential as an anticancer drug. METHODS: Ethanol extract of Gleditsia si ...
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- Yu, Sungryul; Park, Jeong Soo; Paredes, Verenice; Song, Myoung-Chong; Baek, Nam-In; Lee, Sang-Ik; Lim, Jong-Soon; Cho, Nam-Young; Yoon, Jaeseung; Baek, Kwanghee
- Journal of biotechnology 2010 v.145 no.3 pp. 304-309
- Gleditsia sinensis, etc ; Chinese hamsters; agonists; animal ovaries; antagonists; biotechnology; dopamine; dose response; fractionation; humans; medicinal plants; plant extracts; screening; Show all 13 Subjects
- ... To develop a cell-based assay to screen for human dopamine D₁ receptor agonists or antagonists from medicinal plant extracts, a stable Chinese hamster ovary (CHO) cell line (CHO-D1R) expressing the human dopamine D₁ receptor was established using an expression vector containing a scaffold attachment region (SAR) element. CHO-D1R cells showed specific binding to [³H]-SCH23390 with high affinity (K ...