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1. Biochemical Marker Assessment of Chronic Carbamazepine Exposure at Environmentally Relevant Concentrations in Juvenile Common Carp (Cyprinus carpio)

Author:
Xinyue Liang; Zsolt Csenki; Bence Ivánovics; Illés Bock; Balázs Csorbai; József Molnár; Erna Vásárhelyi; Jeffrey Griffitts; Árpád Ferincz; Béla Urbányi; András Ács
Source:
Antioxidants 2022 v.11 no.6 pp. -
ISSN:
2076-3921
Subject:
Cyprinus carpio; DNA; Danio rerio; Oncorhynchus mykiss; anticonvulsants; antioxidants; apoptosis; biomarkers; biotransformation; catalase; drug residues; fish; freshwater; glutathione transferase; glutathione-disulfide reductase; juveniles; lactate dehydrogenase; lipid peroxidation; liver; oxidative stress; superoxide dismutase
Abstract:
... Worldwide, the anticonvulsant drug carbamazepine (CBZ) is the most frequently identified pharmaceutical residue detected in rivers. Reported chronic effects of CBZ in non-target freshwater organisms, particularly fish, include oxidative stress and damage to liver tissues. Studies on CBZ effects in fish are mostly limited to zebrafish and rainbow trout studies. Furthermore, there are only a few chr ...
DOI:
10.3390/antiox11061136

2. Efficient biodegradation of chlortetracycline in high concentration from strong-acidity pharmaceutical residue with degrading fungi

Author:
Yanju Li; Haibo Chen; Yuzhou Wang; Zhengli Yang; Huiyan Zhang
Source:
Journal of hazardous materials 2022 v.424 pp. 127671
ISSN:
0304-3894
Subject:
Micrococcus luteus; acidity; biodegradation; chlortetracycline; drug residues; pH; solid wastes; toxicity
Abstract:
... Chlortetracycline (CTC) pharmaceutical residue with strong acidity and in high CTC concentration is a hazardous solid waste. There is a huge attention but few studies on whether and how the CTC raw residue (CRR) can be degraded in microbiological way. In this study, three self-screened fungi, LJ245, LJ302 and LJ318, were used and thoroughly investigated to remove CTC, strong acidity and biotoxicit ...
DOI:
10.1016/j.jhazmat.2021.127671

3. Enhanced degradation of amiloride over Bi2FeNbO7/bisulfite process: Key factors and mechanism

Author:
Jie Zhao; Fei Wu; Qiang He; Yawei Feng
Source:
Chemosphere 2022 v.300 pp. 134573
ISSN:
0045-6535
Subject:
X-ray diffraction; catalytic activity; deamination; dehalogenation; drug residues; field experimentation; magnetic fields; pH; sodium bisulfite; water treatment
Abstract:
... Construction of Bi₂FeNbO₇/bisulfite system for abatement of pharmaceutical residue was achieved. An attempt to synthesize Bi₂FeNbO₇ through hydrothermal technique was confirmed by X-ray diffraction. The magnetic field experiment revealed that Bi₂FeNbO₇ possessed a saturation magnetization of 6.99 emu/g, indicating magnetic attributes of Bi₂FeNbO₇. Scanning electron microscopy images showed that Bi ...
DOI:
10.1016/j.chemosphere.2022.134573

4. Improved Thyreostatic Drug Detection in Animal Tissues Using Liquid Chromatography–High-Field Asymmetric Waveform Ion Mobility Spectrometry–Mass Spectrometry

Author:
Randy W. Purves; Kim Souster; Michelle West; Azhar M. Huda; Caleb M. E. Fisher; Michael W. Belford; Bryn O. Shurmer
Source:
Journal of agricultural and food chemistry 2022 v.70 no.16 pp. 4785-4791
ISSN:
1520-5118
Subject:
chemical species; food chemistry; liquid chromatography; mass spectrometry; meat; methimazole; methylthiouracil; signal-to-noise ratio; thiouracil; thyroid function
Abstract:
... Thyreostatic drugs (thyreostats) interfere with thyroid function and have been used illegally in animals slaughtered for food. Thyreostat use leads to poorer quality meat, and the drug residues can cause adverse effects in humans. These drugs, with the exception of thiouracil, do not occur naturally and require sensitive methodologies for their detection in animal tissues. Because thyreostats are ...
DOI:
10.1021/acs.jafc.1c06937

5. Isolation and identification of 17β-estradiol degrading bacteria and its degradation pathway

Author:
Qu Zhang; Chao Xue; Gary Owens; Zuliang Chen
Source:
Journal of hazardous materials 2022 v.423 pp. 127185
ISSN:
0304-3894
Subject:
Ochrobactrum; activated sludge; bacteria; bacterial biomass; biodegradation; cell walls; drug residues; estradiol; estrone; glucose; methanol; sodium acetate
Abstract:
... The widespread presence of 17β-estradiol (E2) in the environment is an emerging problem because it poses a potential threat to human health and aquatic organisms. In this study, a strain of E2 degrading bacteria was isolated from activated sludge. 16s rRNA analysis combined with physiological and biochemical detection confirmed that the bacterium was Ochrobactrum sp. strain FJ1. At an initial E2 c ...
DOI:
10.1016/j.jhazmat.2021.127185

6. Probabilistic framework for assessing ecological risk of Contaminants of Emerging Concern: Application to a Canadian lake system

Author:
Gyan Chhipi-Shrestha; Manuel Rodriguez; Sonja Behmel; Rama Pulicharla; Francois Proulx; Kasun Hewage; Rehan Sadiq
Source:
Chemosphere 2022 v.287 pp. 131910
ISSN:
0045-6535
Subject:
acetaminophen; adverse outcome pathways; caffeine; contraceptives; drug residues; ecotoxicology; environmental assessment; freshwater fish; ibuprofen; lakes; phytoplankton; pollutants; probabilistic models; relative risk; risk estimate; salicylic acid; sulfamethoxazole; water pollution; zooplankton; Canada
Abstract:
... Contaminants of Emerging Concern (CECs) in natural water pose risks to ecosystems. The concentration of CECs varies spatially and temporally, and their estimated ecotoxicities differ widely by toxicological studies. This study extensively reviewed literature on ecological risk assessment and proposed a probabilistic framework for assessing ecological risk and its uncertainties (aleatory and episte ...
DOI:
10.1016/j.chemosphere.2021.131910

7. Synthesis of a highly recoverable 3D MnO2/rGO hybrid aerogel for efficient adsorptive separation of pharmaceutical residue

Author:
Billie Yan Zhang Hiew; Wan Ting Tee; Nicholas Yung Li Loh; Kar Chiew Lai; Svenja Hanson; Suyin Gan; Suchithra Thangalazhy-Gopakumar; Lai Yee Lee
Source:
Journal of environmental sciences (China) 2022 v.118 pp. 194-203
ISSN:
1001-0742
Subject:
acetaminophen; acetone; adsorbents; adsorption; aerogels; drug residues; graphene oxide; hydrogen; manganese; nanospheres; pH; sorption isotherms; temperature; thermodynamics; wastewater; water pollution; China
Abstract:
... Water contamination by non-steroidal anti-inflammatory drugs, such as acetaminophen, is an emerging ecological concern. In this study, a new three-dimensional manganese dioxide-engrafted reduced graphene oxide (3D MnO₂/rGO) hybrid aerogel was developed for acetaminophen sequestration. The synthesis involved firstly the self-assembly of GO aerogel, followed by thermal reduction and in-situ MnO₂ gro ...
DOI:
10.1016/j.jes.2021.12.036

8. Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater

Author:
Bui Van Hoi; Cam-Tu Vu; Lan-Anh Phung-Thi; Thao Thi Nguyen; Phuong Thanh Nguyen; Huong Mai; Phuong-Thu Le; Thanh-Hien Nguyen; Dao Thanh Duong; Hue Nguyen Thi; Dung Le-Van; Dinh Binh Chu
Source:
Journal of Analytical Methods in Chemistry (Online) 2021 v.2021 pp. -
ISSN:
2090-8873
Subject:
accuracy; acetaminophen; cation exchange; ciprofloxacin; detection limit; drug residues; electrospray ionization mass spectrometry; frequency; hospitals; ketoprofen; lakes; monitoring; ofloxacin; precision; sampling; solid phase extraction; spectrometers; sulfamethoxazole; surface water; tandem mass spectrometry; trimethoprim; ultra-performance liquid chromatography; wastewater; Vietnam
Abstract:
... In this study, an analytical method for the simultaneous determination of 7 major pharmaceutical residues in Vietnam, namely, carbamazepine, ciprofloxacin, ofloxacin, ketoprofen, paracetamol, sulfamethoxazole, and trimethoprim, in surface water and hospital wastewater has been developed. The method includes enrichment and clean-up steps by solid phase extraction using mix-mode cation exchange, fol ...
DOI:
10.1155/2021/6628285

9. Ecotoxicological risk assessment of contaminants of emerging concern identified by “suspect screening” from urban wastewater treatment plant effluents at a territorial scale

Author:
Antoine Gosset; Laure Wiest; Aurélie Fildier; Christine Libert; Barbara Giroud; Myriam Hammada; Matthieu Hervé; Elisabeth Sibeud; Emmanuelle Vulliet; Philippe Polomé; Yves Perrodin
Source:
Science of the total environment 2021 v.778 pp. 146275
ISSN:
0048-9697
Subject:
analytical methods; atorvastatin; deet; diclofenac; drug residues; ecotoxicology; environment; ephemeral streams; lidocaine; models; risk; risk assessment; rivers; terbutryn; urbanization; wastewater treatment
Abstract:
... Urban wastewater treatment plants (WWTP) are a major vector of highly ecotoxic contaminants of emerging concern (CECs) for urban and sub-urban streams. Ecotoxicological risk assessments (ERAs) provide essential information to public environmental authorities. Nevertheless, ERAs are mainly performed at very local scale (one or few WWTPs) and on pre-selected list of CECs. To cope with these limits, ...
DOI:
10.1016/j.scitotenv.2021.146275

10. Effect of ibuprofen on extracellular polymeric substances (EPS) production and composition, and assessment of microbial structure by quantitative image analysis

Author:
António Melo; Joana Costa; Cristina Quintelas; Eugénio C. Ferreira; Daniela P. Mesquita
Source:
Journal of environmental management 2021 v.293 pp. 112852
ISSN:
0301-4797
Subject:
activated sludge; ammonium; batch fermentation; biopolymers; bioreactors; bioremediation; chemical oxygen demand; community structure; drug residues; exposure duration; flocculation; humic acids; ibuprofen; image analysis; long term effects; microbial activity; microbial biomass; microbial communities; microbial proteins; microorganisms; polysaccharides; stress response; wastewater treatment
Abstract:
... A Sequencing Batch Reactor (SBR) with activated sludge was operated with synthetic wastewater containing ibuprofen (IBU) to investigate the biomass stress-responses under long-term IBU exposure. There were 3 different phases: phase I as the control without IBU for 56 days, phase II (40 days), and phase III (60 days) containing IBU at 10 and 5 mg L⁻¹ each. The overall performance of the SBR as well ...
DOI:
10.1016/j.jenvman.2021.112852

11. Effect of seasonal variation on the occurrences of high-risk pharmaceutical in drain-laden surface water: A risk analysis of Yamuna River

Author:
Afzal Husain Khan; Hamidi Abdul Aziz; Nadeem A. Khan; Aastha Dhingra; Sirajuddin Ahmed; Mu. Naushad
Source:
Science of the total environment 2021 v.794 pp. 148484
ISSN:
0048-9697
Subject:
aquatic ecosystems; drug residues; ecotoxicology; environment; fecal bacteria; monsoon season; phosphates; rain; relative risk; risk assessment; rivers; seasonal variation; streams; surface water; temperature; water supply; India
Abstract:
... The occurrence of pharmaceutical residues in the aquatic ecosystem is an emerging concern of environmentalists. This study primarily investigated the seasonal variation of high-priority pharmaceutical residues in the Yamuna River, accompanied by 22 drains discharge from different parts of Delhi. Five sampling sites were selected for analyzing high-priority pharmaceuticals along with physico-chemic ...
DOI:
10.1016/j.scitotenv.2021.148484

12. Ethno-veterinary herbal formulations: An indigenous strategy to reduce use of antibiotics in the management of livestock health>

Author:
M.N. Balakrishnan Nair; N. Punniamurthy; S.K. Kumar; Darshan Shankar
Source:
Indian journal of comparative microbiology, immunology and infectious diseases 2021 v.42 no.spl pp. 76-82
ISSN:
0974-0147
Subject:
adverse effects; antibiotic resistance; antibiotics; biodiversity; crossbreds; dairy industry; drug residues; humans; immunology; indigenous knowledge; livestock; meat; medicinal plants; microbiology; milk; veterinary services; India
Abstract:
... In India, the dairy sector is an important component in rural livelihoods. To enhance production of milk, a crossbreeding strategy with exotic breeds was introduced in India in the 1960s. The unintended side effect of this strategy was a high incidence of diseases in cross-bred animals and therefore antibiotics had to be extensively used. This led to high drug-residues in the animal products like ...
DOI:
10.5958/0974-0147.2021.00021.0

13. In Danger One of the Largest Aquifers in the World, the Great Mayan Aquifer, Based on Monitoring the Cenotes of the Yucatan Peninsula

Author:
Pablo Antonio Moreno-Pérez; Marivel Hernández-Téllez; Arely Bautista-Gálvez
Source:
Archives of environmental contamination and toxicology 2021 v.81 no.2 pp. 189-198
ISSN:
0090-4341
Subject:
agricultural runoff; animal viruses; aquifers; bacteria; bacterial contamination; drug residues; feces; geographic information systems; georeferencing; groundwater contamination; illicit drugs; infiltration (hydrology); karsts; personal care products; pesticide residues; polycyclic aromatic hydrocarbons; sterols; urban runoff; wastewater; Mexico
Abstract:
... The aquifer flowing beneath the Yucatan Peninsula, México, is one of the largest in the world and is in direct contact with the surface through “cenotes” (sinkholes) that have been documented to be contaminated with various classes of pollutants. The objective of this study was to evaluate the environmental status of the Great Mayan Aquifer through a review of data published on pollution of the ce ...
DOI:
10.1007/s00244-021-00869-5

14. Monitoring drug consumption in Innsbruck during coronavirus disease 2019 (COVID-19) lockdown by wastewater analysis

Author:
Vera Reinstadler; Verena Ausweger; Anna-Lena Grabher; Marco Kreidl; Susanne Huber; Julia Grander; Sandra Haslacher; Klaus Singer; Michael Schlapp-Hackl; Manuel Sorg; Harald Erber; Herbert Oberacher
Source:
Science of the total environment 2021 v.757 pp. 144006
ISSN:
0048-9697
Subject:
COVID-19 infection; Severe acute respiratory syndrome coronavirus 2; acetaminophen; alcohol abuse; alcohol drinking; amphetamine; biomarkers; cocaine; codeine; drug abuse; drug residues; epidemiological studies; health status; lifestyle; methamphetamines; municipal wastewater; pandemic; quarantine; social behavior; trimethoprim; Austria
Abstract:
... The coronavirus disease 2019 (COVID-19) has developed into a serious pandemic with millions of cases diagnosed worldwide. To fight COVID-19 pandemic, over 100 countries instituted either a full or partial lockdown, affecting billions of people. In Tyrol, first lockdown measures were taken on 10 March 2020. On 16 March 2020, a curfew went into force which ended on 1 May 2020. On 19 March 2020, Tyro ...
DOI:
10.1016/j.scitotenv.2020.144006

15. Pharmaceuticals and other urban contaminants threaten Amazonian freshwater ecosystems

Author:
Andreu Rico; Rhaul de Oliveira; Gabriel Silva de Souza Nunes; Cristiana Rizzi; Sara Villa; Isabel López-Heras; Marco Vighi; Andrea Viviana Waichman
Source:
Environment international 2021 v.155 pp. 106702
ISSN:
0160-4120
Subject:
anthropogenic activities; aquatic organisms; biodiversity; chemical pollutants; drug residues; exposure pathways; freshwater ecosystems; hormones; municipal wastewater; personal care products; rivers; sewage effluent; urban areas; water pollution; watersheds; Amazon River; Amazonia; Brazil
Abstract:
... Urban areas in the Brazilian Amazon have grown at an unprecedented rate during the last years. About 90% of the wastewater produced by these urban areas are discharged untreated into Amazonian freshwater ecosystems, constituting a potential environmental pathway for pharmaceuticals and other chemicals consumed by modern societies (e.g. psychostimulants, personal-care products, hormones). The distr ...
DOI:
10.1016/j.envint.2021.106702

16. Tap water contamination: Multiclass endocrine disrupting compounds in different housing types in an urban settlement

Author:
Sze Yee Wee; Ahmad Zaharin Aris; Fatimah Md Yusoff; Sarva Mangala Praveena
Source:
Chemosphere 2021 v.264 pp. 128488
ISSN:
0045-6535
Subject:
bisphenol A; caffeine; dietary exposure; drug residues; electrical conductivity; endocrine-disrupting chemicals; environmental fate; health effects assessments; hormones; pesticide residues; plasticizers; public water supply; residential housing; sulfamethoxazole; tap water; urban areas; water distribution; water pollution; water salinity
Abstract:
... Contamination of endocrine disrupting compounds (EDCs) in tap water is an emerging global issue, and there are abundant influencing factors that have an ambivalent effect on their transportation and fate. Different housing types vary in terms of water distribution system operation and design, water consumption choices, and other hydraulic factors, which potentially affect the dynamics, loadings, an ...
DOI:
10.1016/j.chemosphere.2020.128488

17. Vitamin D3 identified from metabolomic analysis of intestinal contents promotes an antibacterial response in shrimp intestinal immunity

Author:
Ming-Chong Yang; Jin-Xing Wang; Xiu-Zhen Shi
Source:
Aquaculture 2021 v.530 pp. 735951
ISSN:
0044-8486
Subject:
Marsupenaeus japonicus; Vibrio parahaemolyticus; antibiotics; antimicrobial peptides; bacteria; cholecalciferol; drug residues; enzymes; genes; high performance liquid chromatography; homeostasis; immune response; intestinal microorganisms; intestines; metabolism; metabolites; metabolomics; oral administration; prophenoloxidase; shrimp; shrimp culture; signal transduction; survival rate; tandem mass spectrometry; transcriptomics; vibriosis; virulent strains
Abstract:
... Vibrio parahaemolyticus is a critical pathogenic bacterium for the kuruma shrimp, Marsupenaeus japonicus. Antibacterial drug application is the main method to control vibriosis in aquaculture; however, drug residues and the emergence of resistant bacteria have restricted their use. Therefore, the present study aimed to identify metabolites that are likely to play roles in the homeostasis of the in ...
DOI:
10.1016/j.aquaculture.2020.735951

18. A critical evaluation of comparative regulatory strategies for monitoring pharmaceuticals in recycled wastewater

Author:
Olga Miarov; Alon Tal; Dror Avisar
Source:
Journal of environmental management 2020 v.254 pp. 109794
ISSN:
0301-4797
Subject:
bioaccumulation; drug residues; effluents; irrigated farming; monitoring; prioritization; public health; wastewater; wastewater treatment; water policy; water resources; water reuse; Australia; Israel; Singapore; Switzerland; United States
Abstract:
... Pharmaceuticals are a subset of micropollutants, present in the environment in trace concentrations. Because of their persistent nature, these chemicals are of particular concern. Little is known about how mixtures of pharmaceutical residues, found in WWTP effluents, affect the environment or public health. Yet, numerous studies show negative outcomes for both aquatic and terrestrial organisms, su ...
DOI:
10.1016/j.jenvman.2019.109794

19. A physiologically based pharmacokinetic model of doxycycline for predicting tissue residues and withdrawal intervals in grass carp (Ctenopharyngodon idella)

Author:
Ning Xu; Miao Li; Wei-Chun Chou; Zhoumeng Lin
Source:
Food and chemical toxicology 2020 v.137 pp. 111127
ISSN:
0278-6915
Subject:
Ctenopharyngodon idella; Monte Carlo method; aquaculture; cardiac output; doxycycline; drug residues; food safety; gastrointestinal transit; gills; kidneys; liver; muscles; oral administration; pharmacokinetics; prediction; skin (animal)
Abstract:
... The extensive use of doxycycline in aquaculture results in drug residue violations that negatively impact human food safety. This study aimed to develop a physiologically based pharmacokinetic (PBPK) model for doxycycline to predict drug residues and withdrawal times (WTs) in grass carp (Ctenopharyngodon idella) after daily oral administration for 3 days. Physiological parameters including cardiac ...
DOI:
10.1016/j.fct.2020.111127

20. Anti-staphylococcal activity of quaternized mannan from the yeast Candida albicans

Author:
Jana Valáriková; Alžbeta Čížová; Lucia Račková; Slavomír Bystrický
Source:
Carbohydrate polymers 2020 v.240 pp. 116288
ISSN:
0144-8617
Subject:
Candida albicans; Staphylococcus aureus; antibiotic resistance; antimicrobial properties; biocompatible materials; biodegradability; biofilm; cytotoxicity; drug residues; fibroblasts; foods; hemagglutination; hemolysis; humans; mannans; pathogens; yeasts
Abstract:
... Global increase of antibiotic-resistant pathogens as well as elevated content of drug residues in the foodstuffs and the environment urgently calls for new biocompatible antimicrobial biomaterials. Yeast mannans represent readily available source of biodegradable materials for tailor-made derivatives that could be effective in biomedical applications. Here, antimicrobial properties of quaternized ...
DOI:
10.1016/j.carbpol.2020.116288

21. Antibiotic resistance genes are increased by combined exposure to sulfamethoxazole and naproxen but relieved by low-salinity

Author:
Weifu Yan; Rui Bai; Siqi Wang; Xiaochun Tian; Yan Li; Shuhua Wang; Fan Yang; Yong Xiao; Xiaoquan Lu; Feng Zhao
Source:
Environment international 2020 v.139 pp. 105742
ISSN:
0160-4120
Subject:
Eubacterium (genus); Methylophilus; Pseudomonas; antibiotic resistance genes; antibiotics; bacteria; biofilm; drug residues; high-throughput nucleotide sequencing; hosts; microbial communities; microbiome; multiple drug resistance; pollution; probability; quantitative polymerase chain reaction; salinity; sulfamethoxazole
Abstract:
... Combined pollution of antibiotic and non-antibiotic pharmaceutical residues is ubiquitous in realistic polluted environments, which is regarded as a complicated emerging pollution. Herein, high-throughput sequencing and high-throughput quantitative PCR were applied to profile the overall changes in microbial communities and antibiotic resistance genes (ARGs) of biofilms in response to a combinatio ...
DOI:
10.1016/j.envint.2020.105742

22. Antiviral drugs in aquatic environment and wastewater treatment plants: A review on occurrence, fate, removal and ecotoxicity

Author:
Christina Nannou; Anna Ofrydopoulou; Eleni Evgenidou; David Heath; Ester Heath; Dimitra Lambropoulou
Source:
Science of the total environment 2020 v.699 pp. 134322
ISSN:
0048-9697
Subject:
antiviral agents; aquatic environment; drug residues; ecotoxicology; environmental fate; freshwater ecosystems; metabolites; monitoring; oseltamivir; risk; surface water; surveys; wastewater; wastewater treatment; water quality; France; Germany; Japan; North America; South America; Sub-Saharan Africa; United Kingdom
Abstract:
... The environmental release of antiviral drugs is of considerable concern due to potential ecosystem alterations and the development of antiviral resistance. As a result, interest on their occurrence and fate in natural and engineered systems has grown substantially in recent years. The main scope of this review is to fill the void of information on the knowledge on the worldwide occurrence of antiv ...
DOI:
10.1016/j.scitotenv.2019.134322

23. Application of advanced oxidation processes followed by different treatment technologies for hospital wastewater treatment

Author:
Afzal Husain Khan; Nadeem A. Khan; Sirajuddin Ahmed; Aastha Dhingra; Chandra Pratap Singh; Saif Ullah Khan; Ali Akbar Mohammadi; Fazlollah Changani; Mahmood Yousefi; Shamshad Alam; Sergij Vambol; Viola Vambol; Anwar Khursheed; Imran Ali
Source:
Journal of cleaner production 2020 v.269 pp. 122411
ISSN:
0959-6526
Subject:
advanced wastewater treatment; community health; drug residues; effluents; hospitals; hydrogen peroxide; ibuprofen; microorganisms; ofloxacin; oxidation; ozonation; ozone; pH; pollution control; sewage treatment; wastewater; water resources
Abstract:
... Hospital effluents are the sources for complex high percentage of micropollutants and till date no specific treatment have been investigated for the removal of pollutants. These effluents and their complex characteristics pose resistance to unit operation which undergoes in hospital wastewater treatment plants (WWTPs). In other words such complex contaminants are unable to removed completely throu ...
DOI:
10.1016/j.jclepro.2020.122411

24. Application of surface-enhanced Raman spectroscopy in fast detection of toxic and harmful substances in food

Author:
Jing Neng; Qi Zhang; Peilong Sun
Source:
Biosensors & bioelectronics 2020 v.167 pp. 112480
ISSN:
0956-5663
Subject:
Raman spectroscopy; biosensors; drug residues; food additives; food matrix; food pathogens; food safety; mycotoxins; shellfish toxins; toxicity
Abstract:
... Surface-enhanced Raman spectroscopy (SERS) is being considered as a powerful technique in the area of food safety due to its rapidity, sensitivity, portability, and non-destructive features. This review aims to provide a comprehensive understanding of SERS applications in fast detection of toxic and harmful substances in food matrix. The enhancement mechanism of SERS, classification of active subs ...
DOI:
10.1016/j.bios.2020.112480

25. Broad spectrum detection of veterinary drugs with a highly stable metal-organic framework

Author:
Bin Wang; Jing-Hao Liu; Jiamei Yu; Jie Lv; Chen Dong; Jian-Rong Li
Source:
Journal of hazardous materials 2020 v.382 pp. 121018
ISSN:
0304-3894
Subject:
animal-based foods; coordination polymers; detection limit; drug residues; fluorescence; monitoring; nicarbazin; porous media; veterinary drugs; wavelengths
Abstract:
... The broad spectrum detection of veterinary drugs is very important for rapid and large-scale safe screen of animal-derived foods. Metal-organic frameworks (MOFs), as a kind of emerged functional porous materials are quite promising in the chemical sensing and molecular detection. In this work, we report the high-performance broad spectrum detection of 15 commonly-used veterinary drugs through the ...
DOI:
10.1016/j.jhazmat.2019.121018

26. Ciprofloxacin removal using magnetic fullerene nanocomposite obtained from sustainable PET bottle wastes: Adsorption process optimization, kinetics, isotherm, regeneration and recycling studies

Author:
Noha A. Elessawy; Mohamed Elnouby; M.H. Gouda; Hesham A. Hamad; Nahla A. Taha; M. Gouda; Mohamed S. Mohy Eldin
Source:
Chemosphere 2020 v.239 pp. 124728
ISSN:
0045-6535
Subject:
Escherichia coli; adsorption; antibiotic resistance; antibiotics; aquatic environment; catalysts; catalytic activity; ciprofloxacin; drug residues; ecological balance; ecosystems; environmental assessment; feedstocks; ferrocenes; fullerene; human health; magnetism; magnetite; microorganisms; nanocomposites; pollutants; polyethylene terephthalates; recycling; response surface methodology; temperature; thermal degradation; wastes
Abstract:
... Numerous of pollutants threaten our planet, for instance plastic wastes causes a huge potential risk on the environment in addition to many of emergened pollutants as pharmaceutical residue in aquatic environments which affecting ecological balance and in-turn affecting human health. Accordingly, this research proposed an innovative facile, one-step synthesis of functionalized magnetic fullerene n ...
DOI:
10.1016/j.chemosphere.2019.124728

27. Detection, identification and determination of chiral pharmaceutical residues in wastewater: Problems and challenges

Author:
Aysegul Dogan; Justyna Płotka-Wasylka; Dagmara Kempińska-Kupczyk; Jacek Namieśnik; Agata Kot-Wasik
Source:
Trends in analytical chemistry 2020 v.122 pp. 115710
ISSN:
0165-9936
Subject:
analytical methods; drug residues; ecosystems; enantiomers; humans; optical isomerism; wastewater
Abstract:
... Chiral pharmaceuticals (CPs) are widely used in different areas of human life, thus they are frequently detected in different ecosystems. However, before CPs reach the environment, wastewater is subjected to different treatment processes in order to remove them. Nevertheless, such processes may affect the chirality of CPs, thus it is very important to monitor CP levels during the wastewater treatm ...
DOI:
10.1016/j.trac.2019.115710

28. Determination of prescribed and designer benzodiazepines and metabolites in influent wastewater

Author:
Richard Bade; Maulik Ghetia; Jason M. White; Cobus Gerber
Source:
Analytical methods 2020 v.12 no.28 pp. 3637-3644
ISSN:
1759-9679
Subject:
adverse effects; death; diazepam; drug residues; liquid chromatography; markets; mass spectrometry; metabolites; psychotropic agents; toxicity; wastewater; South Australia
Abstract:
... Benzodiazepines are important prescription pharmaceuticals used to help in the treatment of anxiety and sleep disorders. However, they also have a strong potential for abuse. In this respect, illicit benzodiazepines, i.e. not prescribed in Australia and designer benzodiazepines, which are new compounds that are not legally prescribed in any jurisdiction, have emerged in the illicit Australian mark ...
DOI:
10.1039/d0ay00560f

29. Determination of the presence of pathogens and anthelmintic drugs in raw milk and raw milk cheeses from small scale producers in Ireland

Author:
Antonio Lourenco; Maria Fraga-Corral; Lorenzo De Colli; Mary Moloney; Martin Danaher; Kieran Jordan
Source:
Lebensmittel-Wissenschaft + Technologie 2020 v.130 pp. 109347
ISSN:
0023-6438
Subject:
Bacillus cereus; Escherichia coli; Listeria monocytogenes; Salmonella; Staphylococcus aureus; artisan cheese; avermectins; bacteria; benzimidazoles; cheesemaking; drug residues; levamisole; milbemycins; milk filters; morantel; pathogens; public health; raw milk; risk; surveys; Ireland
Abstract:
... This aim of this study was to assess the microbiological and anthelmintic drug residue risks associated with raw milk used for cheesemaking and raw milk cheese, over an 18-month period. Samples of raw milk, milk filters, curd and cheese from nine raw milk artisan cheese producers in the south of Ireland were tested. Numbers of presumptive Bacillus cereus group, Escherichia coli, Salmonella spp., S ...
DOI:
10.1016/j.lwt.2020.109347

30. Development of an integral strategy for non-target and target analysis of site-specific potential contaminants in surface water: A case study of Dianshan Lake, China

Author:
Di Meng; De-ling Fan; Wen Gu; Zhen Wang; Yong-jie Chen; Hong-zhong Bu; Ji-ning Liu
Source:
Chemosphere 2020 v.243 pp. 125367
ISSN:
0045-6535
Subject:
additives; case studies; computer software; drug residues; information processing; lakes; liquid chromatography; mass spectrometry; pesticide residues; pesticides; plastics; pollutants; rapid methods; risk; screening; surface water; surfactants; water pollution; China
Abstract:
... Surface water contains a large number of potential pollutants and their transformation products, which cannot be discovered by normal target analysis alone. To detect site-specific and unknown contaminants in the environment, we established an integral analytical strategy based on liquid chromatography-high resolution mass spectrometry (LC-HRMS) combined with data processing using specific softwar ...
DOI:
10.1016/j.chemosphere.2019.125367

31. Effects of Propranolol on Growth, Lipids and Energy Metabolism and Oxidative Stress Response of Phaeodactylum tricornutum

Author:
Bernardo Duarte; Eduardo Feijão; Ricardo Cruz de Carvalho; Irina A. Duarte; Marisa Silva; Ana Rita Matos; Maria Teresa Cabrita; Sara C. Novais; Marco F. L. Lemos; João Carlos Marques; Isabel Caçador; Patrick Reis-Santos; Vanessa F. Fonseca
Source:
Biology 2020 v.9 no.12 pp. -
ISSN:
2079-7737
Subject:
Phaeodactylum tricornutum; cell growth; cells; classification; coastal ecosystems; drug residues; ecotoxicology; electron transport chain; energy flow; fatty acids; food webs; humans; hypertension; microalgae; mitochondria; models; oxidative stress; oxygen production; phosphotransferases (kinases); photochemistry; photoinhibition; photosystem II; propranolol; receptors; risk assessment; storage; stress response
Abstract:
... Present demographic trends suggest a rise in the contributions of human pharmaceuticals into coastal ecosystems, underpinning an increasing demand to evaluate the ecotoxicological effects and implications of drug residues in marine risk assessments. Propranolol, a non-selective β-adrenoceptor blocker, is used worldwide to treat high blood pressure conditions and other related cardiovascular condit ...
DOI:
10.3390/biology9120478

32. Facile synthesis of highly efficient fluorescent carbon dots for tetracycline detection

Author:
Feng Guo; Zihan Zhu; Zhangqin Zheng; Ying Jin; Xiaoxuan Di; Zhonghao Xu; Hongwei Guan
Source:
Environmental science and pollution research international 2020 v.27 no.4 pp. 4520-4527
ISSN:
0944-1344
Subject:
Fourier transform infrared spectroscopy; carbon quantum dots; crabs; detection limit; drug residues; feeds; fluorescence; food security; human health; photoluminescence; risk; seafood waste; signal-to-noise ratio; tetracycline; thermal cracking; transmission electron microscopy; ultraviolet-visible spectroscopy
Abstract:
... Rampant use of tetracycline in animal feed is a threat to food security, the environment, and human health because of the risk of drug residues. Therefore, it is necessary to establish a sensitive, efficient, and reliable method for qualitative and quantitative detection of tetracycline. In this paper, we synthesized fluorescent carbon dots (FCDs) by thermal cracking of crab shell waste, and obtai ...
DOI:
10.1007/s11356-019-06779-3

33. Ibuprofen Degradation and Associated Bacterial Communities in Hyporheic Zone Sediments

Author:
Cyrus Rutere; Kirsten Knoop; Malte Posselt; Adrian Ho; Marcus A. Horn
Source:
Microorganisms 2020 v.8 no.8 pp. -
ISSN:
2076-2607
Subject:
Acidobacteria; Actinobacteria; Bacteroidetes; Gemmatimonadetes; Pseudomonas; Sphingomonas; acetates; bacteria; bacterial communities; drug residues; effluents; genes; hyporheic zone; ibuprofen; pollution control; quantitative polymerase chain reaction; ribosomal RNA; rivers; sediments; wastewater
Abstract:
... Ibuprofen, a non-steroidal anti-inflammatory pain reliever, is among pharmaceutical residues of environmental concern ubiquitously detected in wastewater effluents and receiving rivers. Thus, ibuprofen removal potentials and associated bacteria in the hyporheic zone sediments of an impacted river were investigated. Microbially mediated ibuprofen degradation was determined in oxic sediment microcos ...
DOI:
10.3390/microorganisms8081245

34. Integrated assessment of sulfate-based AOPs for pharmaceutical active compound removal from wastewater

Author:
Luca Sbardella; Inmaculada Velo Gala; Joaquim Comas; Serni Morera Carbonell; Ignasi Rodríguez-Roda; Wolfgang Gernjak
Source:
Journal of cleaner production 2020 v.260 pp. 121014
ISSN:
0959-6526
Subject:
active ingredients; drug residues; ecological footprint; effluents; electric energy consumption; electric power; energy; environmental impact; life cycle assessment; oxidation; photolysis; sulfates; ultraviolet radiation; wastewater; wastewater treatment; water pollution
Abstract:
... Advanced oxidation processes (AOPs) have been proposed as tertiary treatments for municipal WWTP effluents. UV-activated peroxydisulfate (PDS) and peroxymonosulfate (PMS) are viable technological alternatives for treating secondary WWTP effluent containing PhACs. This article examines the feasibility of applying UV/PDS and UV/PMS technologies at pilot scale, assessing their energy and cost require ...
DOI:
10.1016/j.jclepro.2020.121014

35. Is sequential batch reactor an efficient technology to protect recipient against non-steroidal anti-inflammatory drugs and paracetamol in treated wastewater?

Author:
Katarzyna Kołecka; Magdalena Gajewska; Stanisław Cytawa; Piotr Stepnowski; Magda Caban
Source:
Bioresource technology 2020 v.318 pp. 124068
ISSN:
0960-8524
Subject:
acetaminophen; activated sludge; batch systems; decontamination; diclofenac; drug residues; ecotoxicology; effluents; environmental fate; ibuprofen; metabolites; propionates; wastewater treatment; water pollution; Poland
Abstract:
... The tested facility was a wastewater treatment plant (WWTP) in Swarzewo, where the wastewater treatment takes place in aeration chambers with activated sludge using sequential batch reactors (SBRs). The concentration of the following pharmaceuticals: ibuprofen, paracetamol, flurbiprofen, naproxen, diclofenac, and its metabolites 5OH-diclofenac and 4OH-diclofenac was tested in influents and effluen ...
DOI:
10.1016/j.biortech.2020.124068

36. Mass spectrometry approaches to ensure food safety

Author:
Irene Domínguez; Antonia Garrido Frenich; Roberto Romero-González
Source:
Analytical methods 2020 v.12 no.9 pp. 1148-1162
ISSN:
1759-9679
Subject:
analytical chemistry; drug residues; food contamination; instrumentation; matrix-assisted laser desorption-ionization mass spectrometry; monitoring; pesticides; retrospective studies; screening; veterinary drugs
Abstract:
... Mass spectrometry (MS) is widely used in the food safety area, being fully implemented in both routine analysis and research laboratories. Indeed, MS is considered an essential tool for the monitoring of food contamination. Continuous improvements in the instrumentation resulted in a breakthrough in analytical chemistry and consequently in food sciences. The advances in MS enabled the development ...
DOI:
10.1039/c9ay02681a

37. Metal Probe Microextraction Coupled to Dielectric Barrier Discharge Ionization–Mass Spectrometry for Detecting Drug Residues in Organisms

Author:
Qiao Lu; Rongkun Lin; Chao Du; Yifan Meng; Manqing Yang; Renato Zenobi; Wei Hang
Source:
Analytical chemistry 2020 v.92 no.8 pp. 5921-5928
ISSN:
1520-6882
Subject:
Paramecium; Plasmodium falciparum; chemical species; desorption; detection limit; drug residues; falciparum malaria; fish; gases; ionization; mass spectrometry; microextraction; pyrimethamine; tungsten
Abstract:
... In this study, a novel method for the direct coupling of metal probe microextraction (MPME) and a dielectric barrier discharge ionization (DBDI) source with mass spectrometry (MS) is reported. Analytes adsorbed on a tungsten needle were directly transferred to the DBDI source via rapid thermal desorption, which resulted in a limit of detection as low as 8 pg/mL. This is in part due to the “active ...
DOI:
10.1021/acs.analchem.0c00004

38. Multi-class analysis of 46 antimicrobial drug residues in pond water using UHPLC-Orbitrap-HRMS and application to freshwater ponds in Flanders, Belgium

Author:
T. Goessens; S. Huysman; N. De Troyer; A. Deknock; P. Goethals; L. Lens; L. Vanhaecke; S. Croubels
Source:
Talanta 2020 v.220 pp. 121326
ISSN:
0039-9140
Subject:
agricultural pollution; amoxicillin; antibiotic resistance; aquatic environment; biodiversity; cephalosporins; detection limit; drug residues; freshwater; high performance liquid chromatography; macrolides; mass spectrometry; multiresidue analysis; nitrofurans; pesticides; ponds; quinolones; screening; solid phase extraction; sulfonamides; tetracyclines; ultra-performance liquid chromatography; uncertainty; Belgium
Abstract:
... Increasing anthropogenic pressure and agricultural pollution raises concerns regarding antimicrobial resistance and biodiversity loss in aquatic environments. In order to protect and restore water resources and biodiversity, antimicrobial drug residues should be monitored in all aquatic environments including pond water. Consequently, the objective of this research was to develop and validate a no ...
DOI:
10.1016/j.talanta.2020.121326

39. Multi-residue determination of micropollutants in Nigerian fish from Lagos lagoon using ultrasound assisted extraction, solid phase extraction and ultra-high-performance liquid chromatography tandem mass spectrometry

Author:
Idera Fabunmi; Natalie Sims; Kathryn Proctor; Aderonke Oyeyiola; Temilola Oluseyi; Kehinde Olayinka; Barbara Kasprzyk-Hordern
Source:
Analytical methods 2020 v.12 no.16 pp. 2114-2122
ISSN:
1759-9679
Subject:
Solea solea; detection limit; drug residues; eyes; fish; gills; high performance liquid chromatography; multiresidue analysis; muscles; pollutants; quantitative analysis; screening; solid phase extraction; tandem mass spectrometry; trimethoprim; ultra-performance liquid chromatography; ultrasonics
Abstract:
... This study proposes a new, fast and sensitive multi-residue method for simultaneous screening of different classes of pharmaceuticals in fish using an ultrasonic assisted extraction (UAE) followed by solid phase extraction (SPE) as clean-up step and by ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). The analysis was carried out by spiking ∼1 g wet tissue of sole ...
DOI:
10.1039/d0ay00411a

40. Occurrence and removal of illicit drugs in different wastewater treatment plants with different treatment techniques

Author:
Yanghui Deng; Changsheng Guo; Heng Zhang; Xingxing Yin; Like Chen; Daishe Wu; Jian Xu
Source:
Environmental sciences Europe 2020 v.32 no.1 pp. 28
ISSN:
2190-4707
Subject:
batch systems; cocaine; drug residues; effluents; epidemiology; methamphetamines; models; monitoring; occurrence; population; public health; research; risk; sampling; sludge; wastewater; wastewater treatment; water management; Europe
Abstract:
... BACKGROUND: As a class of contaminants of emerging concern (CECs), illicit drugs should be taken into account in the water management because of their social and public health risks. Wastewater treatment plants (WWTPs) are usually considered as the source and sink of contaminants, and drug residues are observed in their effluents due to the inefficient removal of CECs. In this study, wastewater sa ...
DOI:
10.1186/s12302-020-00304-x

41. Occurrence of Stimulant Drugs of Abuse in a San Diego, CA, Stream and their Consumption Rates in the Neighboring Community

Author:
Kayo Watanabe; Christine M. Batikian; Dianne Pelley; Benjamin Carlson; Jerome Pitt; Richard M. Gersberg
Source:
Water, air, and soil pollution 2020 v.231 no.5 pp. 202
ISSN:
0049-6979
Subject:
amphetamine; caffeine; cocaine; drug residues; excretion; foresters; humans; liquid chromatography; metabolites; methamphetamines; sewage; sewage treatment; solid phase extraction; stream flow; streams; sucralose; surface water; tandem mass spectrometry; wastewater; weather; California; Europe
Abstract:
... Levels of amphetamine, methamphetamine, cocaine, and benzoylecgonine (BE), the metabolite of cocaine, were quantitated by solid phase extraction and liquid chromatography with tandem mass spectrometry (LC/MS/MS) in Forester Creek in San Diego County, CA, and in raw wastewater from the region’s sewage treatment plant. Drug residues in these surface waters were detected with 100% frequency. Mean con ...
DOI:
10.1007/s11270-020-04565-3

42. Pharmaceutical and personal care product residues in a macrophyte pond-constructed wetland treating wastewater from a university campus: Presence, removal and ecological risk assessment

Author:
Rayco Guedes-Alonso; Sarah Montesdeoca-Esponda; José A. Herrera-Melián; Raquel Rodríguez-Rodríguez; Zeneida Ojeda-González; Vanessa Landívar-Andrade; Zoraida Sosa-Ferrera; José J. Santana-Rodríguez
Source:
Science of the total environment 2020 v.703 pp. 135596
ISSN:
0048-9697
Subject:
aquatic environment; constructed wetlands; drug residues; effluents; environmental assessment; hormone supplements; macrophytes; personal care products; ponds; risk; risk assessment; sewage; stabilizers; steroid hormones; toxicity; triazoles; wastewater; wastewater treatment
Abstract:
... Pharmaceuticals and personal care products (PPCPs) constitute a group of chemicals of concern because of their potential toxicity when reaching aquatic environments. Wastewaters are one of the main pathways of introduction into the environment of the chemical compounds used in PPCPs because, in most cases, wastewater treatment facilities are not 100% efficient in their removal. This problem is acc ...
DOI:
10.1016/j.scitotenv.2019.135596

43. Pharmaceuticals removal and nutrient recovery from wastewaters by Chlamydomonas acidophila

Author:
Ania Escudero; Colin Hunter; Joanne Roberts; Karin Helwig; Ole Pahl
Source:
Biochemical engineering journal 2020 v.156 pp. 107517
ISSN:
1369-703X
Subject:
Chlamydomonas; ammonium; aquatic environment; caffeine; clarithromycin; drug residues; effluents; lidocaine; microalgae; nutrients; phosphates; photons; propranolol; waste utilization; wastewater; wastewater treatment
Abstract:
... Wastewater treatment plants are a major source of human pharmaceutical residues (PR) in the aquatic environment, which are considered to be of emerging concern. The microalga Chlamydomonas acidophila has shown to be a promising technology to recover the nutrients from wastewater and therefore, the aim of this study was to evaluate the ability of this species to also remove PRs commonly present in ...
DOI:
10.1016/j.bej.2020.107517

44. Pharmaceuticals residues and xenobiotics contaminants: Occurrence, analytical techniques and sustainable alternatives for wastewater treatment

Author:
Milina de Oliveira; Breno Emanuel Farias Frihling; Jannaina Velasques; Fernando Jorge Corrêa Magalhães Filho; Priscila Sabioni Cavalheri; Ludovico Migliolo
Source:
Science of the total environment 2020 v.705 pp. 135568
ISSN:
0048-9697
Subject:
drug residues; environmental health; gas chromatography; high performance liquid chromatography; issues and policy; lipophilicity; mass spectrometry; molecular weight; pollution; sewage; sewage treatment; wastewater; wastewater treatment; water solubility; wetlands; xenobiotics
Abstract:
... Emerging contaminants are increasingly present in the environment, and their appearance on both the environment and health of living beings are still poorly understood by society. Conventional sewage treatment facilities that are under validity and were designed years ago are not developed to remove pharmaceutical compounds, their main focus is organic and bacteriological removal. Pharmaceutical r ...
DOI:
10.1016/j.scitotenv.2019.135568

45. Population physiologically based modeling of pirlimycin milk concentrations in dairy cows

Author:
A.P. Woodward; D. Morin; T. Whittem
Source:
Journal of dairy science 2020 v.103 no.11 pp. 10639-10650
ISSN:
0022-0302
Subject:
bovine mastitis; dairy cows; data collection; drug residues; economics; food safety; mammary glands; meat; milk; milk production; nonlinear mixed effects models; pharmacokinetics; pirlimycin; prediction; risk; udders; variance
Abstract:
... Predictions of drug residues in milk are critical in food protection and are a major consideration in the economics of treatment of mastitis in dairy cows. Nonlinear mixed-effects modeling (NLME) has been advocated as a suitable pharmaco-statistical method for the study of drug residues in milk. Recent developments in physiologically based pharmacokinetic (PBPK) modeling of intramammary drugs allo ...
DOI:
10.3168/jds.2020-18760

46. Recent trends in disposal and treatment technologies of emerging-pollutants- A critical review

Author:
Nadeem A. Khan; Saif Ullah Khan; Sirajuddin Ahmed; Izharul Haq Farooqi; Mahmood Yousefi; Ali Akbar Mohammadi; Fazlollah Changani
Source:
Trends in analytical chemistry 2020 v.122 pp. 115744
ISSN:
0165-9936
Subject:
antibiotics; climate change; developing countries; disease outbreaks; disinfectants; drug residues; effluents; emerging diseases; hospitals; pollution; population growth; surface water; wastewater
Abstract:
... Recently pharmaceuticals are emerging as a major source of pollution for the environment. It has been well observed that the effluent discharge from hospitals has an eminent quantity of chemical waste as antibiotics, disinfectants and other treatments wastes. Pharmaceutical effluents are bioactive and their existence in the environment has been found harmful to both aquatic life and humans. In dev ...
DOI:
10.1016/j.trac.2019.115744

47. Regulatory review of the environmental risk assessment of veterinary medicinal products in the European Union, with particular focus on the centralised authorisation procedure

Author:
Julia Fabrega; Ricardo Carapeto
Source:
Environmental sciences Europe 2020 v.32 no.1 pp. 99
ISSN:
2190-4707
Subject:
European Union; drug residues; environmental assessment; information; international cooperation; marketing; risk; risk assessment; veterinary drugs; water pollution; Europe
Abstract:
... In the EU, the requirement for a two-tier-based environmental risk assessment for a veterinary medicinal product applies for marketing authorisations submitted since 1993. This article outlines the framework for conducting environmental risk assessments and provides information about the outcomes and type of substances that often require a higher tier assessment due to environmental concerns, and ...
DOI:
10.1186/s12302-020-00374-x

48. Sample treatment based on molecularly imprinted polymers for the analysis of veterinary drugs in food samples: a review

Author:
I. S. Ibarra; J. M. Miranda; I. Pérez-Silva; C. Jardinez; G. Islas
Source:
Analytical methods 2020 v.12 no.23 pp. 2958-2977
ISSN:
1759-9679
Subject:
cost analysis; detection limit; dietary exposure; drug residues; food contamination; growth promotion; livestock and meat industry; medical treatment; molecular imprinting; polymers; product safety; sorbents; veterinary drugs
Abstract:
... The use of veterinary drugs in medical treatments and in the livestock industry is a recurrent practice. When applied in subtherapeutic doses over prolonged times, they can also act as growth promoters. However, residues of these substances in foods present a risk to human health. Their analysis is thus important and can help guarantee consumer safety. The critical point in each analytical techniq ...
DOI:
10.1039/d0ay00533a

49. Simultaneous determination of eight nitrofuran residues in shellfish and fish using ultra-high performance liquid chromatography–tandem mass spectrometry

Author:
Guanxiang Yuan; Zhou Zhu; Peng Yang; Shaoyou Lu; Honghe Liu; Wenjing Liu; Guihua Liu
Source:
Journal of food composition and analysis 2020 v.92 pp. 103540
ISSN:
0889-1575
Subject:
aquaculture; detection limit; drug residues; fish; food contamination; furaltadone; furazolidone; liquid chromatography; nitrofurantoin; pollution; shellfish; shrimp; standard deviation; tandem mass spectrometry; China
Abstract:
... Illegal use of nitrofurans (NFs) in aquaculture is of great concern for food safety throughout the world. A liquid chromatography-based method coupled to tandem mass spectrometry was developed and validated for measuring levels of four conventional NFs (nitrofurantoin, furazolidone, nitrofurazone, and furaltadone) and four additional NFs (nifursol, nifuroxazide, nifurpirinol, and sodium nifurstyre ...
DOI:
10.1016/j.jfca.2020.103540

50. Synergistic interaction of diclofenac and its metabolites with selected antibiotics and amygdalin in wastewaters

Author:
Marzena Matejczyk; Piotr Ofman; Katarzyna Dąbrowska; Renata Świsłocka; Włodzimierz Lewandowski
Source:
Environmental research 2020 v.186 pp. 109511
ISSN:
0013-9351
Subject:
Escherichia coli K12; ampicillin; amygdalin; antimicrobial properties; bacteria; biodegradation; biosensors; diclofenac; drug residues; genotoxicity; growth retardation; kanamycin; luminescence; metabolites; monitoring; nonsteroidal anti-inflammatory agents; oxidative stress; synergism; viability; wastewater
Abstract:
... Diclofenac (DCF), a non-steroidal anti-inflammatory drug (NSAID) belongs to one of the most frequently detected pharmaceutical residues in the environment. Little is known on the interactions of DCF as well as its major biodegradation metabolites 4′-OHDCF and 5-OHDCF with chemical compounds found in wastewater, including antibiotics such as ampicillin and kanamycin. In the present work we examined ...
DOI:
10.1016/j.envres.2020.109511