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You searched for: Author "Pan, Cai-Yuan" Remove constraint Author: "Pan, Cai-Yuan" Subject drugs Remove constraint Subject: drugs Subject fluorescence Remove constraint Subject: fluorescence Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Photo-responsive camptothecin-based polymeric prodrug coated silver nanoparticles for drug release behaviour tracking via the nanomaterial surface energy transfer (NSET) effect

Author:
Pan, Cai-Yuan,   et al.   ; Li, Jiao-Yang; Qiu, Liang; Xu, Xiao-Fei; Hong, Chun-Yan; Zhang, Wen-Jian;     Show all 6 Authors
Source:
Journal of materials chemistry 2018 v.6 no.11 pp. 1678-1687
ISSN:
2050-7518
Subject:
composite polymers; drug delivery systems; drugs; energy transfer; fluorescence; in vitro studies; nanoparticles; nanosilver; polymerization
Abstract:
... A hybrid drug delivery system was successfully fabricated by attaching a camptothecin (CPT)-based polymeric prodrug onto the surface of silver nanoparticles (AgNPs). PEG was employed as a macro-RAFT agent in RAFT polymerization to synthesize a branched star copolymer, to which CPT is linked through the photo-responsive o-nitrobenzyl linkage. In vitro tests indicate that the fluorescence of CPT in ...
DOI:
10.1039/c7tb02998e

2. Silver Nanoparticles Covered with pH-Sensitive Camptothecin-Loaded Polymer Prodrugs: Switchable Fluorescence “Off” or “On” and Drug Delivery Dynamics in Living Cells

Author:
Pan, Cai-Yuan,   et al.   ; Qiu, Liang; Li, Jia-Wei; Hong, Chun-Yan;     Show all 4 Authors
Source:
ACS applied materials & interfaces 2017 v.9 no.46 pp. 40887-40897
ISSN:
1944-8252
Subject:
cytotoxicity; drug delivery systems; drugs; energy transfer; fluorescence; human cell lines; in vitro studies; lysosomes; nanoparticles; nanosilver; neoplasms; pH; polymerization; polymers
Abstract:
... A unique drug delivery system, in which silver nanoparticles (AgNPs) are covered with camptothecin (CPT)-based polymer prodrug, has been developed, and the polymer prodrug, in which the CPT is linked to the polymer side chains via an acid-labile β-thiopropionate bond, is prepared by RAFT polymerization. For poly(2-(2-hydroxyethoxy)ethyl methacrylate-co-methacryloyloxy-3-thiahexanoyl-camptothecin)@ ...
DOI:
10.1021/acsami.7b14070

3. A Unique Aliphatic Tertiary Amine Chromophore: Fluorescence, Polymer Structure, and Application in Cell Imaging

Author:
Pan, Cai-Yuan,   et al.   ; Sun, Miao; Hong, Chun-Yan;     Show all 3 Authors
Source:
Journal of the American Chemical Society 2012 v.134 no.51 pp. 20581-20584
ISSN:
1520-5126
Subject:
cytotoxicity; drugs; fluorescence; fluorescent dyes; image analysis; photoluminescence; polymers; tertiary amines; vapors
Abstract:
... Although photoluminescence of tertiary aliphatic amines has been extensively studied, the usage of this fundamental chromophore as a fluorescent probe for various applications has unfortunately not been realized because their uncommon fluorescence is easily quenched, and strong fluorescence has been observed only in vapor phase. The objective of this study is how to retain the strong fluorescence ...
DOI:
10.1021/ja310236m