U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject term elderly Remove constraint Subject term: elderly
Start Over

Search

10,624  Search Results

« Previous | 1 - 20 of 10,624 |
Number of results to display per page

Search Results

1. 2′-Fucosyllactose Ameliorates Oxidative Stress Damage in d-Galactose-Induced Aging Mice by Regulating Gut Microbiota and AMPK/SIRT1/FOXO1 Pathway

Author:
Jin Wang; Jia-Qiang Hu; Yu-Jie Song; Jia Yin; Yuan-Yi-Fei Wang; Bo Peng; Bo-Wei Zhang; Jing-Min Liu; Lu Dong; Shuo Wang
Source:
Foods 2022 v.11 no.2 pp. -
ISSN:
2304-8158
Subject:
apoptosis; brain; breast milk; elderly; immunity; inflammation; intestinal microorganisms; intestines; models; oligosaccharides; oxidative stress; probiotics; protective effect; reactive oxygen species
Abstract:
... The imbalance of reactive oxygen species is the main cause in aging, accompanied by oxidative stress. As the most abundant in human milk oligosaccharides (HMOs), 2′-Fucosyllactose (2′-FL) has been confirmed to have great properties in immunity regulation and anti-inflammatory. The research on 2′-FL is focused on infants currently, while there is no related report of 2′-FL for the elderly. A d-gala ...
DOI:
10.3390/foods11020151

2. A Degradable-Renewable Ionic Skin Based on Edible Glutinous Rice Gel

Author:
Shu Tian; Yihang Xing; You Long; Hongshuang Guo; Sijia Xu; Yiming Ma; Chiyu Wen; Qingsi Li; Xinmeng Liu; Lei Zhang; Jing Yang
Source:
ACS applied materials & interfaces 2022 v.14 no.4 pp. 5122-5133
ISSN:
1944-8252
Subject:
adhesion; amylases; amylopectin; amylose; biocompatibility; body temperature; elderly; electronics; energy; enzyme activity; gels; glutinous rice; heart rate; humans; pollution; quality of life; raw materials; speech; wastes
Abstract:
... Traditional wearable devices are commonly nonrecyclable and nondegradable, resulting in energy waste and environmental pollution. Here, a household degradable and renewable ionic skin based on edible glutinous rice gel is developed for a strain, temperature and salivary enzyme activity sensor. This gel depends on intermolecular and intramolecular H-bonds among amylopectin and amylose, and this pre ...
DOI:
10.1021/acsami.1c24352

3. A System of Remote Patients’ Monitoring and Alerting Using the Machine Learning Technique

Author:
M. Dhinakaran; Khongdet Phasinam; Joel Alanya-Beltran; Kingshuk Srivastava; D. Vijendra Babu; Sitesh Kumar Singh
Source:
Journal of food quality 2022 v.2022 pp. -
ISSN:
1745-4557
Subject:
accidents; elderly; food quality; health services; industry; information storage; patients; prediction
Abstract:
... Machine learning has become an essential tool in daily life, or we can say it is a powerful tool in the majority of areas that we wish to optimize. Machine learning is being used to create techniques that can learn from labelled or unlabeled information, as well as learn from their surroundings. Machine learning is utilized in various areas, but mainly in the healthcare industry, where it provides ...
DOI:
10.1155/2022/6274092

4. A composite indicator to measure sustainable water use in Portugal: A compromise programming approach

Author:
Maria de Belém Costa Freitas; António Xavier; Rui Fragoso; Carla Antunes
Source:
Journal of environmental management 2022 v.311 pp. 114791
ISSN:
0301-4797
Subject:
educational status; elderly; environmental management; humans; income; irrigation; population density; tourism; water supply; Portugal
Abstract:
... Clean water is an important resource for maintaining human life, economic activities, and ecosystems' survival. Nevertheless, its irregular distribution and occasional scarcity lead to the need to promote its sustainable use. To assess the current situation and the dynamics of sustainable water use, it is crucial to identify the main factors affecting it and to propose monitoring indicators. This ...
DOI:
10.1016/j.jenvman.2022.114791

5. A mechanistic insight into the biological activities of urolithins as gut microbial metabolites of ellagitannins

Author:
Seyyed Hossein Hasheminezhad; Motahareh Boozari; Mehrdad Iranshahi; Omid Yazarlu; Amirhossein Sahebkar; Maede Hasanpour; Milad Iranshahy
Source:
Phytotherapy research 2022 v.36 no.1 pp. 112-146
ISSN:
0951-418X
Subject:
Alzheimer disease; Rubus chamaemorus; anti-aging properties; anti-inflammatory activity; biogenesis; biomarkers; cardioprotective effect; cardiovascular diseases; clinical trials; digestive system; elderly; glycemic effect; intestinal microorganisms; liver diseases; metabolites; mitochondria; mitogen-activated protein kinase; mitophagy; noninsulin-dependent diabetes mellitus; nutritive value; pathophysiology; pharmacokinetics; phytotherapy; research; tea
Abstract:
... Urolithins are the gut metabolites produced from ellagitannin‐rich foods such as pomegranates, tea, walnuts, as well as strawberries, raspberries, blackberries, and cloudberries. Urolithins are of growing interest due to their various biological activities including cardiovascular protection, anti‐inflammatory activity, anticancer properties, antidiabetic activity, and antiaging properties. Severa ...
DOI:
10.1002/ptr.7290

6. A nationwide study of air pollution from particulate matter and daily hospitalizations for respiratory diseases in Italy

Author:
Matteo Renzi; Matteo Scortichini; Francesco Forastiere; Francesca de' Donato; Paola Michelozzi; Marina Davoli; Claudio Gariazzo; Giovanni Viegi; Massimo Stafoggia; Carla Ancona; Simone Bucci; Michela Bonafede; Alessandro Marinaccio; Stefania Argentini; Roberto Sozzi; Sergio Bonomo; Salvatore Fasola; Stefania La Grutta; Achille Cernigliaro; Salvatore Scondotto; Sandra Baldacci; Sara Maio; Gaetano Licitra; Antonino Moro; Paola Angelini; Laura Bonvicini; Serena Broccoli; Marta Ottone; Paolo Giorgi Rossi; Annamaria Colacci; Federica Parmagnani; Andrea Ranzi; Claudia Galassi; Enrica Migliore; Lucia Bisceglia; Antonio Chieti; Giuseppe Brusasca; Giuseppe Calori; Sandro Finardi; Alessandro Nanni; Nicola Pepe; Paola Radice; Camillo Silibello; Gianni Tinarelli; Francesco Uboldi; Giuseppe Carlino; BEEP collaborative Group
Source:
Science of the total environment 2022 v.807 pp. 151034
ISSN:
0048-9697
Subject:
air pollution; asthma; elderly; environment; hospitals; humidity; meta-analysis; morbidity; particulates; remote sensing; respiratory system; temperature; time series analysis; urbanization; Italy
Abstract:
... The relationship between air pollution and respiratory morbidity has been widely addressed in urban and metropolitan areas but little is known about the effects in non-urban settings. Our aim was to assess the short-term effects of PM10 and PM2.5 on respiratory admissions in the whole country of Italy during 2006–2015. We estimated daily PM concentrations at the municipality level using satellite ...
DOI:
10.1016/j.scitotenv.2021.151034

7. A prospective study on clinical effect and immune regulation on cytokines secreted by Th cells of aerosolized traditional Chinese medicine on elderly patients with AECOPD

Author:
Guo Dong Wang; Qiang Li; Yi Ting Han; Teng Zhang
Source:
Phytomedicine plus 2022 v.2 no.3 pp. 100282
ISSN:
2667-0313
Subject:
Oriental traditional medicine; T-lymphocytes; aerosols; asthma; blood gases; blood serum; cough; cytokines; elderly; fever; gerontology; herbal medicines; hospitals; lung function; prospective studies
Abstract:
... : To observe the treatment effect and immune regulation of aerosol inhalation of Chinese herbal medicine on elderly patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). : A total of 84 elderly patients with AECOPD, who were admitted to the Department of Geriatrics in Hangzhou Hospital of Traditional Chinese Medicine from March 2019 to December 2020, were randomly div ...
DOI:
10.1016/j.phyplu.2022.100282

8. A recommended amount of hydrolyzed protein improves physiological function by regulating gut microbiota in aged mice

Author:
Xinyi Wang; Shourong Lu; Zhifeng Fang; Hongchao Wang; Jinlin Zhu; Jianxin Zhao; Hao Zhang; Kan Hong; Wenwei Lu; Wei Chen
Source:
Food research international 2022 v.154 pp. 110970
ISSN:
0963-9969
Subject:
Bifidobacterium; Peptococcus; Streptococcus; absorption; blood serum; dietary protein; digestion; elderly; females; food research; high protein diet; industry; interleukin-10; interleukin-6; intestinal microorganisms; muscle tissues; muscles; protein energy ratio; protein hydrolysates; small intestine
Abstract:
... Dietary proteins play a critical role in maintaining the health of elderly people. Although experts recommend that elderly people consume more protein, a high-protein diet may add to the burden of elderly people with degraded digestion and absorption functions. The effects of a normal or high-protein diet and those of a whole or hydrolyzed protein diet on bone and muscle health and gastrointestina ...
DOI:
10.1016/j.foodres.2022.110970

9. A review of some common African spices with antihypertensive potential

Author:
Raphael I. Adeoye; Enoch B. Joel; Adedoyin Igunnu; Rotimi O. Arise; Sylvia O. Malomo
Source:
Journal of food biochemistry 2022 v.46 no.1 pp. e14003
ISSN:
0145-8884
Subject:
Xylopia aethiopica; anthraquinones; blood pressure; cardiac glycosides; chemical constituents of plants; dietary supplements; drug therapy; elderly; flavonoids; heart; histology; hypertension; lifestyle; obesity; pathogenesis; polyphenols; saponins; simvastatin; toxicology; Africa
Abstract:
... Hypertension is the most common non‐communicable disease, with about 1.28 billion hypertensive people worldwide. It is more prevalent in men than women and more common in the elderly. Hereditary, age, obesity, lifestyle, diet, alcohol, and chronic metabolic diseases are the major risk factors of hypertension. Treating hypertension is a complex process as there are several mechanisms responsible fo ...
DOI:
10.1111/jfbc.14003

10. A review on oral tactile sensitivity: measurement techniques, influencing factors and its relation to food perception and preference

Author:
Jing Liu; Camilla Cattaneo; Maria Papavasileiou; Lisa Methven; Wender L.P. Bredie
Source:
Food quality and preference 2022 v.100 pp. 104624
ISSN:
0950-3293
Subject:
elderly; food acceptability; food texture; mouthfeel; nationalities and ethnic groups; sensation; texture
Abstract:
... Texture perception and mouthfeel are important factors in food acceptance and rejection. Despite the contribution of oral tactile sensation to perception of food texture, it has been understudied. This review addresses oral tactile sensitivity in relation to measurement methods, factors that influence sensitivity, and its association with texture perception and preference. Notably, the advantages ...
DOI:
10.1016/j.foodqual.2022.104624

11. Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age

Author:
Marcha Badenhorst; Phebe de Heus; Angelika Auer; Birthe Tegtmeyer; Alexander Stang; Katharina Dimmel; Alexander Tichy; Jakub Kubacki; Claudia Bachofen; Eike Steinmann; Jessika M. V. Cavalleri
Source:
Equine veterinary journal 2022 v.54 no.2 pp. 379-389
ISSN:
0425-1644
Subject:
DNA; Equidae; Hepacivirus; albumins; bile; cross-sectional studies; elderly; gamma-glutamyltransferase; genetic variation; geographical distribution; glutamate dehydrogenase; hepatitis; horses; luciferase; mixed infection; pathogenesis; phylogeny; polymerase chain reaction; precipitin tests; seroprevalence; Austria
Abstract:
... BACKGROUND: Equine parvovirus‐hepatitis (EqPV‐H) research is in its infancy. Information regarding prevalence, geographical distribution, genetic diversity, pathogenesis and risk factors enhances understanding of this potentially fatal infection. OBJECTIVES: Determining the prevalence of EqPV‐H in Austrian equids. Investigating factors increasing probability of infection, liver‐associated biochemi ...
DOI:
10.1111/evj.13444

12. Active forest management accelerates carbon storage in plantation forests in Lishui, southern China

Author:
Jiaojiao Diao; Jinxun Liu; Zhiliang Zhu; Xinyuan Wei; Mingshi Li
Source:
Forest ecosystems 2022 v.9 pp. 100004
ISSN:
2197-5620
Subject:
Cunninghamia lanceolata; Pinus massoniana; Quercus; aboveground biomass; biosphere; carbon; carbon dioxide; carbon sequestration; carbon sinks; climate change; elderly; energy; forest damage; forest management; forest plantations; forests; industry; simulation models; China
Abstract:
... China has committed to achieving peak CO₂ emissions before 2030 and carbon neutrality before 2060; therefore, accelerated efforts are needed to better understand carbon accounting in industry and energy fields as well as terrestrial ecosystems. The carbon sink capacity of plantation forests contributes to the mitigation of climate change. Plantation forests throughout the world are intensively man ...
DOI:
10.1016/j.fecs.2022.100004

13. Aesthetic preferences for deadwood in forest landscape: A case study in Italy

Author:
Alessandro Paletto; Claudia Becagli; Isabella De Meo
Source:
Journal of environmental management 2022 v.311 pp. 114829
ISSN:
0301-4797
Subject:
Castanea; Fagus sylvatica subsp. sylvatica; Picea abies; Pinus nigra; aesthetic value; aesthetics; case studies; coppicing; dead wood; educational status; elderly; environmental management; females; forests; landscapes; males; people; questionnaires; shrublands; Italy
Abstract:
... In the last decades, the structural and functional role of standing dead trees and lying deadwood in forests has been widely recognized by scientific community and forest managers. However, a large amount of deadwood in forests can have negative impacts on recreational forests by reducing the aesthetic value and site attractiveness. The aims of the present study are to investigate whether deadwood ...
DOI:
10.1016/j.jenvman.2022.114829

14. Age-specific disparity in life loss per death attributable to ambient temperature: A nationwide time-series study in China

Author:
Weilin Zeng; Min Yu; Weizhen Mai; Maigeng Zhou; Chunliang Zhou; Yize Xiao; Zhulin Hou; Yanjun Xu; Tao Liu; Jianxiong Hu; Xiaojun Xu; Lifeng Lin; Ruying Hu; Junhua Li; Donghui Jin; Mingfang Qin; Weiwei Gong; Peng Yin; Yiqing Xu; Jianpeng Xiao; Xing Li; Guanhao He; Siqi Chen; Yonghui Zhang; Cunrui Huang; Shannon Rutherford; Xianbo Wu; Biao Huang; Wenjun Ma
Source:
Environmental research 2022 v.203 pp. 111834
ISSN:
0013-9351
Subject:
ambient temperature; cold; death; elderly; meta-analysis; meteorological data; mortality; nonlinear models; research; time series analysis; China
Abstract:
... Age-specific discrepancy of mortality burden attributed to temperature, measured as years of life lost (YLL), has been rarely investigated. We investigated age-specific temperature-YLL rates (per 100,000) relationships and quantified YLL per death caused by non-optimal temperature in China. We collected daily meteorological data, population data and daily death counts from 364 locations in China d ...
DOI:
10.1016/j.envres.2021.111834

15. Aging and Light Stress Result in Overlapping and Unique Gene Expression Changes in Photoreceptors

Author:
Spencer E. Escobedo; Sarah C. Stanhope; Ziyu Dong; Vikki M. Weake
Source:
Genes 2022 v.13 no.2 pp. -
ISSN:
2073-4425
Subject:
DNA repair; blue light; death; elderly; eye diseases; eyes; gene expression; homeostasis; immune response; longevity; membrane potential; mitochondria; photoreceptors; phototransduction; transcription (genetics); transcriptome; vision
Abstract:
... Advanced age is one of the leading risk factors for vision loss and eye disease. Photoreceptors are the primary sensory neurons of the eye. The extended photoreceptor cell lifespan, in addition to its high metabolic needs due to phototransduction, makes it critical for these neurons to continually respond to the stresses associated with aging by mounting an appropriate gene expression response. He ...
DOI:
10.3390/genes13020264

16. Aging and comorbidities influence the risk of hospitalization and mortality in diabetic patients experiencing severe hypoglycemia

Author:
Alessandro Nuzzo; Andrea Brignoli; Maria C. Ponziani; Marco Zavattaro; Flavia Prodam; Luigi M. Castello; Gian C. Avanzi; Paolo Marzullo; Gianluca Aimaretti
Source:
Nutrition, metabolism, and cardiovascular diseases 2022 v.32 no.1 pp. 160-166
ISSN:
0939-4753
Subject:
elderly; heart diseases; hospitals; hypoglycemia; metabolism; mortality; nutrition; obesity; regression analysis; renal failure; risk; risk assessment; Italy
Abstract:
... To assess the risk of hospitalization and mortality within 1 year of severe hypoglycaemia and theirs clinical predictors.We retrospectively examined 399 admissions for severe hypoglycemia in adults with DM at the Emergency Department (ED) of the University Hospital of Novara (Italy) between 2012–2017, and we compared the clinical differences between older (aged ≥65 years) and younger individuals ( ...
DOI:
10.1016/j.numecd.2021.09.016

17. Alcohol consumption, poor lifestyle choices, and air pollution worsen cognitive function in seniors: a cohort study in China

Author:
Lizhen Han; Jinzhu Jia
Source:
Environmental science and pollution research 2022 v.29 no.18 pp. 26877-26888
ISSN:
0944-1344
Subject:
air pollution; air quality; alcohol drinking; beers; cognition; cohort studies; education; elderly; lifestyle; longevity; meat consumption; models; research; vegetables; China
Abstract:
... Based on the complexity of cognitive-related influences and the specificity of Chinese liquor culture, this study aimed to explore the associations and potential interactions between demographic characteristics, alcohol consumption, life and atmospheric environment, and cognitive function in seniors through a comprehensive analysis, in order to provide evidence support and feasible recommendations ...
DOI:
10.1007/s11356-021-17891-8

18. Ameliorative effect of ethoxylated chalcone-based MAO-B inhibitor on behavioural predictors of haloperidol-induced Parkinsonism in mice: evidence of its antioxidative role against Parkinson’s diseases

Author:
Naseer Maliyakkal; Uzma Saleem; Fareeha Anwar; Muhammad Ajmal Shah; Bashir Ahmad; Filzah Umer; Mohammad Ali Abdullah Almoyad; Della Grace Thomas Parambi; Asmy Appadath Beeran; Lekshmi R Nath; Lotfi Aleya; Bijo Mathew
Source:
Environmental science and pollution research 2022 v.29 no.5 pp. 7271-7282
ISSN:
0944-1344
Subject:
Parkinson disease; animal models; biomarkers; brain; chalcone; dopamine; dose response; elderly; haloperidol; locomotion; neurotransmitters; nitrites; norepinephrine; oral administration; oxidative stress; pollution; research; serotonin
Abstract:
... Parkinson’s disease is a progressive neurodegenerative disorder that affects mostly elderly people above the age of 60. Previously, we have reported that the ethoxylated chalcone derivative (E)-1-(4-ethoxyphenyl)-3-(fluorophenyl)prop-2-en-1-one (E7) showed potent, reversible, and competitive MAO-B inhibition with an IC₅₀ value of 0.053 μm. The present study aims to investigate the anti-Parkinson a ...
DOI:
10.1007/s11356-021-15955-3

19. An Update on Vitamin D Deficiency Status in Malaysia

Author:
Zaleha Md Isa; Nor Rumaizah Mohd Nordin; Muhammad Hilmi Mahmud; Syahirah Hashim
Source:
Nutrients 2022 v.14 no.3 pp. -
ISSN:
2072-6643
Subject:
adolescents; atopic dermatitis; blood serum; bone mineralization; breast feeding; calcium; clothing; elderly; epilepsy; geophysics; kidney diseases; liver diseases; malabsorption; melanin; nationalities and ethnic groups; postmenopause; pregnancy; protective effect; spina bifida; Malaysia
Abstract:
... Vitamin D is essential for maintaining serum calcium levels, ensuring sufficient bone mineralization, immunomodulatory properties, and a protective effect on the cardiovascular system, renal disease, cancer, as well as in pregnancy. Vitamin D deficiency is prevalent worldwide, and it is not related to a country’s development index. However, the data on vitamin D deficiencies are primarily taken fr ...
DOI:
10.3390/nu14030567

20. An in silico hierarchal approach for drug candidate mining and validation of natural product inhibitors against pyrimidine biosynthesis enzyme in the antibiotic-resistant Shigella flexneri

Author:
Zarrin Basharat; Kanwal Khan; Khurshid Jalal; Diyar Ahmad; Ajmal Hayat; Ghallab Alotaibi; Abdulaziz Al Mouslem; Faris F. Aba Alkhayl; Ahmad Almatroudi
Source:
Infection, genetics, and evolution 2022 v.98 pp. 105233
ISSN:
1567-1348
Subject:
Shigella flexneri; antibiotic resistance; antibiotic resistance genes; bacteria; biosynthesis; computer simulation; databases; dysentery; elderly; enzymes; etiological agents; evolution; genomics; infection; orotic acid; shigellosis; streptomycin; therapeutics
Abstract:
... Shigella flexneri is the main causative agent of the communicable diarrheal disease, shigellosis. It is estimated that about 80–165 million cases and > 1 million deaths occur every year due to this disease. S. flexneri causes dysentery mostly in young children, elderly and immunocompromised patients, all over the globe. Recently, due to the emergence of S. flexneri antibiotic resistance strains, i ...
DOI:
10.1016/j.meegid.2022.105233