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1. Fabrication of hexagonal boron nitride based 2D nanopore sensor for the assessment of electro‐chemical responsiveness of human serum transferrin protein

Author:
Saharia, Jugal; Bandara, Y. M. Nuwan D. Y.; Lee, Jung Soo; Wang, Qingxiao; Kim, Moon J.; Kim, Min Jun
Source:
Electrophoresis 2020 v.41 no.7-8 pp. 630-637
ISSN:
0173-0835
Subject:
normal distribution,   etc   ; DNA; blood serum; boron nitride; capacitance; dielectric properties; electric potential difference; electrophoresis; humans; nanopores; pH; protein composition; transferrin;     Show all 13 Subjects
Abstract:
... In this work, we present a step‐by‐step workflow for the fabrication of 2D hexagonal boron nitride (h‐BN) nanopores which are then used to sense holo‐human serum transferrin (hSTf) protein at pH ∼8 under applied voltages ranging from +100 mV to +800 mV. 2D nanopores are often used for DNA, however, there is a great void in the literature for single‐molecule protein sensing and this, to the best of ...
DOI:
10.1002/elps.201900336

2. An analytic description of electrodynamic dispersion in free-flow zone electrophoresis

Author:
Dutta, Debashis
Source:
Journal of chromatography 2015 v.1404 pp. 124-130
ISSN:
0021-9673
Subject:
normal distribution,   etc   ; Monte Carlo method; chromatography; electric field; electroosmosis; electrophoresis; hydrodynamic dispersion; variance;     Show all 8 Subjects
Abstract:
... The present work analyzes the electrodynamic dispersion of sample streams in a free-flow zone electrophoresis (FFZE) chamber resulting due to partial or complete blockage of electroosmotic flow (EOF) across the channel width by the sidewalls of the conduit. This blockage of EOF has been assumed to generate a pressure-driven backflow in the transverse direction for maintaining flow balance in the s ...
DOI:
10.1016/j.chroma.2015.05.035
PubMed:
26044384
PubMed Central:
PMC4470816

3. pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect B Biointerfaces

Author:
Saisyo, Atsuyuki; Nakamura, Hideaki; Fang, Jun; Tsukigawa, Kenji; Greish, Khaled; Furukawa, Hiroyuki; Maeda, Hiroshi
Source:
Colloids and surfaces 2016 v.138 pp. 128-137
ISSN:
0927-7765
Subject:
normal distribution,   etc   ; adverse effects; antineoplastic activity; cisplatin; colloids; composite polymers; cytotoxicity; drug therapy; electrophoresis; light scattering; mice; micelles; neoplasms; pH; particle size; permeability; pharmacokinetics; tissues; weight loss;     Show all 19 Subjects
Abstract:
... Cisplatin (CDDP) is widely used to treat various cancers. However, its distribution to normal tissues causes serious adverse effects. For this study, we synthesized a complex of styrene-maleic acid copolymer (SMA) and CDDP (SMA–CDDP), which formed polymeric micelles, to achieve tumor-selective drug delivery based on the enhanced permeability and retention (EPR) effect. SMA–CDDP is obtained by regu ...
DOI:
10.1016/j.colsurfb.2015.11.032

4. Experimental determination of sample stream focusing with fluorescent dye

Author:
Taylor, Jay; Stubley, G.D.; Ren, Carolyn L.
Source:
Electrophoresis 2008 v.29 no.14 pp. 2953-2959
ISSN:
0173-0835
Subject:
normal distribution,   etc   ; crosslinking; electrophoresis; fluorescein; streams; variance;     Show all 6 Subjects
Abstract:
... This study aims to develop an experimental method for determining the focused-sample stream width in microfluidic chips. The focused-sample stream width in the junction of a cross-linked microchannel is determined by the distance between the two streamlines dividing the focusing sheath streams and the sample stream, which should be insensitive to the sample properties. However, the commonly used F ...
DOI:
10.1002/elps.200700931