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You searched for: Subject term environmental assessment Remove constraint Subject term: environmental assessment Subject term drug residues Remove constraint Subject term: drug residues Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Probabilistic framework for assessing ecological risk of Contaminants of Emerging Concern: Application to a Canadian lake system

Author:
Gyan Chhipi-Shrestha; Manuel Rodriguez; Sonja Behmel; Rama Pulicharla; Francois Proulx; Kasun Hewage; Rehan Sadiq
Source:
Chemosphere 2022 v.287 pp. 131910
ISSN:
0045-6535
Subject:
acetaminophen; adverse outcome pathways; caffeine; contraceptives; drug residues; ecotoxicology; environmental assessment; freshwater fish; ibuprofen; lakes; phytoplankton; pollutants; probabilistic models; relative risk; risk estimate; salicylic acid; sulfamethoxazole; water pollution; zooplankton; Canada
Abstract:
... Contaminants of Emerging Concern (CECs) in natural water pose risks to ecosystems. The concentration of CECs varies spatially and temporally, and their estimated ecotoxicities differ widely by toxicological studies. This study extensively reviewed literature on ecological risk assessment and proposed a probabilistic framework for assessing ecological risk and its uncertainties (aleatory and episte ...
DOI:
10.1016/j.chemosphere.2021.131910

2. Ciprofloxacin removal using magnetic fullerene nanocomposite obtained from sustainable PET bottle wastes: Adsorption process optimization, kinetics, isotherm, regeneration and recycling studies

Author:
Noha A. Elessawy; Mohamed Elnouby; M.H. Gouda; Hesham A. Hamad; Nahla A. Taha; M. Gouda; Mohamed S. Mohy Eldin
Source:
Chemosphere 2020 v.239 pp. 124728
ISSN:
0045-6535
Subject:
Escherichia coli; adsorption; antibiotic resistance; antibiotics; aquatic environment; catalysts; catalytic activity; ciprofloxacin; drug residues; ecological balance; ecosystems; environmental assessment; feedstocks; ferrocenes; fullerene; human health; magnetism; magnetite; microorganisms; nanocomposites; pollutants; polyethylene terephthalates; recycling; response surface methodology; temperature; thermal degradation; wastes
Abstract:
... Numerous of pollutants threaten our planet, for instance plastic wastes causes a huge potential risk on the environment in addition to many of emergened pollutants as pharmaceutical residue in aquatic environments which affecting ecological balance and in-turn affecting human health. Accordingly, this research proposed an innovative facile, one-step synthesis of functionalized magnetic fullerene n ...
DOI:
10.1016/j.chemosphere.2019.124728

3. Pharmaceutical and personal care product residues in a macrophyte pond-constructed wetland treating wastewater from a university campus: Presence, removal and ecological risk assessment

Author:
Rayco Guedes-Alonso; Sarah Montesdeoca-Esponda; José A. Herrera-Melián; Raquel Rodríguez-Rodríguez; Zeneida Ojeda-González; Vanessa Landívar-Andrade; Zoraida Sosa-Ferrera; José J. Santana-Rodríguez
Source:
Science of the total environment 2020 v.703 pp. 135596
ISSN:
0048-9697
Subject:
aquatic environment; constructed wetlands; drug residues; effluents; environmental assessment; hormone supplements; macrophytes; personal care products; ponds; risk; risk assessment; sewage; stabilizers; steroid hormones; toxicity; triazoles; wastewater; wastewater treatment
Abstract:
... Pharmaceuticals and personal care products (PPCPs) constitute a group of chemicals of concern because of their potential toxicity when reaching aquatic environments. Wastewaters are one of the main pathways of introduction into the environment of the chemical compounds used in PPCPs because, in most cases, wastewater treatment facilities are not 100% efficient in their removal. This problem is acc ...
DOI:
10.1016/j.scitotenv.2019.135596

4. Regulatory review of the environmental risk assessment of veterinary medicinal products in the European Union, with particular focus on the centralised authorisation procedure

Author:
Julia Fabrega; Ricardo Carapeto
Source:
Environmental sciences Europe 2020 v.32 no.1 pp. 99
ISSN:
2190-4707
Subject:
European Union; drug residues; environmental assessment; information; international cooperation; marketing; risk; risk assessment; veterinary drugs; water pollution; Europe
Abstract:
... In the EU, the requirement for a two-tier-based environmental risk assessment for a veterinary medicinal product applies for marketing authorisations submitted since 1993. This article outlines the framework for conducting environmental risk assessments and provides information about the outcomes and type of substances that often require a higher tier assessment due to environmental concerns, and ...
DOI:
10.1186/s12302-020-00374-x

5. Comparison of regulatory frameworks of environmental risk assessments for human pharmaceuticals in EU, USA, and Canada

Author:
Dongyoung Lee; Kyungho Choi
Source:
Science of the total environment 2019 v.671 pp. 1026-1035
ISSN:
0048-9697
Subject:
European Union; active ingredients; aquatic environment; chronic diseases; drug residues; ecosystems; environmental assessment; environmental health; guidelines; humans; laws and regulations; marketing; pharmaceutical industry; risk; risk assessment; risk reduction; Canada; United States
Abstract:
... With the growth of the aging population and increasing prevalence of chronic diseases, more medicinal products are expected to be used in growing amount. Consequently, numerous pharmaceutical residues have been detected in aquatic environments worldwide. Because of the potential impacts of pharmaceutical residues on the ecosystem, ensuring the environmental safety of the pharmaceutical products be ...
DOI:
10.1016/j.scitotenv.2019.03.372

6. Determination of pharmaceutical active compounds in Ceyhan River, Turkey: Seasonal, spatial variations and environmental risk assessment

Author:
Evsen Yavuz Guzel; Fatma Cevik; Nebile Daglioglu
Source:
Human and ecological risk assessment 2019 v.25 no.8 pp. 1980-1995
ISSN:
1549-7860
Subject:
active ingredients; analgesics; aquatic environment; caffeine; central nervous system; diazepam; diclofenac; drug residues; environmental assessment; fluconazole; lidocaine; liquid chromatography; risk; risk assessment; river water; rivers; solid phase extraction; tandem mass spectrometry; water pollution; Turkey (country)
Abstract:
... Pharmaceutical pollution has gained attention with the development of analytical technology. The occurrence of 91 pharmaceutically active compounds from variety of drug groups including pain killers, antimicrobials, cardiovascular drugs, hypolipidemic drugs, central nervous system drugs, and stimulants was investigated in Ceyhan River, Turkey. Pharmaceutically active compounds were examined at 9 s ...
DOI:
10.1080/10807039.2018.1479631

7. Metabolization of pharmaceuticals by plants after uptake from water and soil: A review

Author:
Christian W. Klampfl
Source:
Trends in analytical chemistry 2019 v.111 pp. 13-26
ISSN:
0165-9936
Subject:
biosolids; drug residues; environmental assessment; fertilizers; humans; irrigation; metabolites; sewage treatment; soil
Abstract:
... Residues of pharmaceuticals are ubiquitous in the environment, due to the increased use of drugs for treating humans and animals. If in agriculture water or biosolids from sewage treatment plants or manure from treated animals are used for irrigation or as a fertilizer respectively, drug residues may come into contact with plants. Subsequently these substances may be taken up, be translocated and ...
DOI:
10.1016/j.trac.2018.11.042

8. Prioritised pharmaceuticals in German estuaries and coastal waters: Occurrence and environmental risk assessment

Author:
Danijela Kötke; Juergen Gandrass; Zhiyong Xie; Ralf Ebinghaus
Source:
Environmental pollution 2019 pp. -
ISSN:
0269-7491
Subject:
aquatic organisms; clarithromycin; coastal water; coasts; detection limit; drug residues; ecotoxicology; electrospray ionization mass spectrometry; environmental assessment; estuaries; liquid chromatography; prioritization; risk assessment; seawater; spectrometers; sulfamethoxazole; surface water; Baltic Sea
Abstract:
... In this study a target analysis approach with method detection limits down to 0.01 ng L−1 was developed in order to determine ultra-trace pharmaceuticals in seawater of the German coast and their estuaries. The selection of target analytes based on a prioritisation commissioned by the German Environmental Agency considering occurrence in German surface waters, production volumes and ecotoxicologic ...
DOI:
10.1016/j.envpol.2019.113161

9. Ranking and prioritizing pharmaceuticals in the aquatic environment of China

Author:
Yan Li; Luyan Zhang; Xianshu Liu; Jie Ding
Source:
Science of the total environment 2019 v.658 pp. 333-342
ISSN:
0048-9697
Subject:
aquatic environment; benzylpenicillin; diclofenac; drug residues; environmental assessment; environmental impact; erythromycin; monitoring; pollutants; prioritization; risk assessment; therapeutics; wastewater treatment; water pollution; China
Abstract:
... Pharmaceuticals have become “persistent” pollutants in the aquatic environment, due to their wide usage in daily life and their continuous release into the aquatic environment. Hence, prioritization and ranking lists are required to screen for target compounds as part of risk assessments. A ranking system based on three criteria, such as occurrence, exposure potential and ecological effects, was d ...
DOI:
10.1016/j.scitotenv.2018.12.048

10. Individual and mixture effects of selected pharmaceuticals on larval development of the estuarine shrimp Palaemon longirostris

Author:
Enrique González-Ortegón; Julian Blasco; Elena Nieto; Miriam Hampel; Lewis Le Vay; Luis Giménez
Source:
Science of the total environment 2016 v.540 pp. 260-266
ISSN:
0048-9697
Subject:
Palaemon serratus; clofibric acid; clotrimazole; coastal water; diclofenac; drug residues; ecotoxicology; environmental assessment; estuaries; experimental design; fungicides; instars; larvae; larval development; life history; lipids; nonsteroidal anti-inflammatory agents; pollutants; risk assessment; salinity; shrimp; temperature; toxicity
Abstract:
... Few ecotoxicological studies incorporate within the experimental design environmental variability and mixture effects when assessing the impact of pollutants on organisms. We have studied the combined effects of selected pharmaceutical compounds and environmental variability in terms of salinity and temperature on survival, development and body mass of larvae of the estuarine shrimp Palaemon longi ...
DOI:
10.1016/j.scitotenv.2015.06.081

11. Tracer tests and uncertainty propagation to design monitoring setups in view of pharmaceutical mass flow analyses in sewer systems

Author:
Kai Klepiszewski; Silvia Venditti; Christian Koehler
Source:
Water research 2016 v.98 pp. 319-325
ISSN:
0043-1354
Subject:
X-radiation; case studies; cost benefit analysis; drug residues; emissions; environmental assessment; hospitals; hydrologic cycle; mass flow; material flow analysis; monitoring; pollutants; pollution; risk assessment; sewer systems; surface water; tracer techniques; uncertainty; Europe
Abstract:
... The development of a strategic approach to manage pollution of surface waters with pharmaceutical residues is in centre of interest in Europe. In this context a lack of reliable standard procedures for sampling and subsequent assessment of pharmaceutical mass flows in the water cycle has been identified. Authoritative assessment of relevant substance concentrations and flows is essential for envir ...
DOI:
10.1016/j.watres.2016.04.008

12. An integrated approach for prioritizing pharmaceuticals found in the environment for risk assessment, monitoring and advanced research

Author:
Daniel J. Caldwell; Frank Mastrocco; Luigi Margiotta-Casaluci; Bryan W. Brooks
Source:
Chemosphere 2014 v.115 pp. 4-12
ISSN:
0045-6535
Subject:
European Union; drug residues; environmental assessment; environmental monitoring; fish; hazard characterization; mammals; models; pharmacology; prioritization; risk; surface water
Abstract:
... Numerous active pharmaceutical ingredients (APIs), approved prior to enactment of detailed environmental risk assessment (ERA) guidance in the EU in 2006, have been detected in surface waters as a result of advancements in analytical technologies. Without adequate knowledge of the potential hazards these APIs may pose, assessing their environmental risk is challenging. As it would be impractical t ...
DOI:
10.1016/j.chemosphere.2014.01.021

13. Highly sensitive determination of 68 psychoactive pharmaceuticals, illicit drugs, and related human metabolites in wastewater by liquid chromatography–tandem mass spectrometry

Author:
Viola L. Borova; Niki C. Maragou; Pablo Gago-Ferrero; Constantinos Pistos; Νikolaos S. Τhomaidis
Source:
Analytical and bioanalytical chemistry 2014 v.406 no.17 pp. 4273-4285
ISSN:
1618-2642
Subject:
adsorbents; amphetamines; anesthetics; anticonvulsants; antidepressants; antipsychotics; barbiturates; benzodiazepines; cocaine; detection limit; drug residues; environmental assessment; humans; illicit drugs; ionization; liquid chromatography; metabolites; narcotics; physicochemical properties; solid phase extraction; tandem mass spectrometry; wastewater; wastewater treatment; Aegean Sea; Greece
Abstract:
... The present work describes the development and validation of a highly sensitive analytical method for the simultaneous determination of 68 compounds, including illicit drugs (opiates, opioids, cocaine compounds, amphetamines, and hallucinogens), psychiatric drugs (benzodiazepines, barbiturates, anesthetics, antiepileptics, antipsychotics, antidepressants, and sympathomimetics), and selected human ...
DOI:
10.1007/s00216-014-7819-3

14. Evaluation of an isotope dilution liquid chromatography tandem mass spectrometry method for pharmaceuticals in fish

Author:
B. Du; P. Perez-Hurtado; B.W. Brooks; C.K. Chambliss
Source:
Journal of chromatography 2012 v.1253 no. pp. 177-183
ISSN:
0021-9673
Subject:
Salmo trutta; detection limit; drug residues; environmental assessment; fish; fish fillets; food contamination; ionization; isotope dilution technique; liquid chromatography; liver; metabolites; tandem mass spectrometry; tissues; Utah
Abstract:
... An isotope dilution liquid chromatography-tandem mass spectrometry (LC–MS/MS) method was successfully developed and applied for analysis of 15 pharmaceuticals and 2 pharmaceutically active metabolites in fish tissues. This method relied on electrospray ionization (ESI), for which the influence of sample matrix on analyte ionization efficiencies remains a persistent challenge to environmental analy ...
DOI:
10.1016/j.chroma.2012.07.026