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1. Patterns of estrogenic activity in the Baltic Sea

Author:
Deich, Carina; Kanwischer, Marion; Jähne, Martin; Waniek, Joanna J.
Source:
Chemosphere 2019
ISSN:
0045-6535
Subject:
endocrine system,   etc   ; Blastobotrys adeninivorans; autumn; bioassays; estradiol; estrogenic properties; risk; risk assessment; spring; surface water; water temperature; yeasts; Baltic Sea;     Show all 13 Subjects
Abstract:
... Compounds such as estradiol and ethinylestradiol belong to contaminants of emerging concern, as they can disrupt the endocrine system of an organism with a hormonal system. The determination of such compounds is still challenging due to required low detection and quantification limits. Bioassays have proved to be sensitive tools for investigating the full potential of all compounds that can elicit ...
DOI:
10.1016/j.chemosphere.2019.124870

2. Evaluation of the 17-α-Ethinyl Estradiol Sorption Capacity in Soil

Author:
de Oliveira, Renan Angrizani; Tardelli, Edgard Robles; Jozala, Angela Faustino; Grotto, Denise
Source:
Water, air, and soil pollution 2019 v.230 no.4 pp. 85
ISSN:
0049-6979
Subject:
endocrine system,   etc   ; adsorption; drugs; estradiol; high performance liquid chromatography; mathematical models; pH; soil; soil sampling; sorption isotherms; texture; vegetation; Brazil;     Show all 13 Subjects
Abstract:
... 17-α-Ethinyl estradiol (EE2) is a widely used drug that acts in the endocrine system and in the environment; even at low concentrations, it causes extensive damage to organisms. The most relevant factors for understanding the EE2 degradation and transport mechanisms in soil are through sorption studies. This study investigated the sorption capacity of EE2 in soil collected amidst vegetation in the ...
DOI:
10.1007/s11270-019-4136-7

3. Assessing the effects of Awba dam sediment (Nigeria) on the steroidogenesis of H295R cells using different extraction methods

Author:
Natoli, Luigi; Luci, Giacomo; Mennillo, Elvira; Adeogun, Aina O.; Arukwe, Augustine
Source:
The Science of the total environment 2019 v.650 pp. 121-131
ISSN:
0048-9697
Subject:
endocrine system,   etc   ; benthic organisms; binding capacity; detritus; endocrine-disrupting chemicals; estradiol; fish; food webs; freshwater; genes; humans; ingestion; messenger RNA; non-polar compounds; sediments; steroidogenesis; testosterone; Nigeria;     Show all 18 Subjects
Abstract:
... In the present study, H295R human cells were used to investigate the endocrine disruptor potential of three different sediments extracts taken from a Nigerian tropical freshwater dam (Awba Dam), using three extraction methods that allowed a selective consideration of contaminants based on their binding affinity, which is mainly driven by polarity, to sediment particles. After exposure to different ...
DOI:
10.1016/j.scitotenv.2018.08.409

4. Long-term exposure to waterborne nonylphenol alters reproductive physiological parameters in economically important marine fish

Author:
Saravanan, Manoharan; Nam, Sang-Eun; Eom, Hye-Jin; Lee, Do-Hee; Rhee, Jae-Sung
Source:
Comparative biochemistry and physiology 2019 v.216 pp. 10-18
ISSN:
1532-0456
Subject:
endocrine system,   etc   ; Pagrus major; Sebastes melanops; aquatic environment; chronic exposure; cortisol; estradiol; gonadosomatic index; hepatosomatic index; juveniles; marine fish; messenger RNA; nonylphenols; synthetic estrogens; vitellogenin;     Show all 15 Subjects
Abstract:
... Low concentrations of nonylphenol (NP) in aquatic environment can induce drastic effects on the endocrine system in animals. In this study, we examined the modulatory effects of NP on reproductive and physiological parameters in juveniles of the red seabream and black rockfish following waterborne NP exposure (0, 1, 10, and 50 μg L−1) for 60 days. In red seabream exposed to 50 μg L−1 NP, plasma le ...
DOI:
10.1016/j.cbpc.2018.11.009

5. Graphene/multi-walled carbon nanotubes as an adsorbent for pipette-tip solid-phase extraction for the determination of 17β-estradiol in milk products

Author:
Yuan, Yanan; Wang, Mingwei; Jia, Nan; Zhai, Chengcheng; Han, Yehong; Yan, Hongyuan
Source:
Journal of chromatography 2019 v.1600 pp. 73-79
ISSN:
0021-9673
Subject:
endocrine system,   etc   ; adsorbents; adverse effects; carbon nanotubes; detection limit; estradiol; food chain; high performance liquid chromatography; human nutrition; milk; quantitative analysis; screening; solid phase extraction; solvents; standard deviation; washing;     Show all 16 Subjects
Abstract:
... The illegal addition and abuse of 17β-estradiol (E2) in food has led to its accumulation in the body through the food chain, resulting in adverse effects on the human body through interference with the endocrine system. Because milk and dairy products are major components of the human diet, screening as well as quantitative analysis of E2 in these food types is important. In this work, a three-dim ...
DOI:
10.1016/j.chroma.2019.04.055

6. Recent advances in the detection of 17β-estradiol in food matrices: A review

Author:
Pu, Hongbin; Huang, Zhibin; Sun, Da-Wen; Fu, Haohua
Source:
Critical reviews in food science and nutrition 2019 v.59 no.13 pp. 2144-2157
ISSN:
1549-7852
Subject:
endocrine system,   etc   ; Raman spectroscopy; active ingredients; colorimetry; electrochemistry; endocrine-disrupting chemicals; estradiol; estrogenic properties; fluorescence; food intake; food matrix; food safety; high performance liquid chromatography; nutrition risk assessment; pollution;     Show all 15 Subjects
Abstract:
... Pollution of endocrine disrupting chemicals has become a global issue. As one of the hormonally active compounds, 17β-estradiol produces the strongest estrogenic effect when it enters the organism exogenously including food intakes, bringing potential harmfulness such as malfunction of the endocrine system. Therefore, in order to assure food safety and avoid potential risks of 17β-estradiol to hum ...
DOI:
10.1080/10408398.2019.1611539

7. The effect of estrone and estradiol on the expression of the orexin/hypocretin system in the porcine uterus during early pregnancy

Author:
Kiezun, M.; Dobrzyn, K.; Rytelewska, E.; Kisielewska, K.; Gudelska, M.; Szeszko, K.; Zaobidna, E.; Bors, K.; Wyrebek, J.; Mykytiuk, A.; Kaminski, T.; Smolinska, N.
Source:
Domestic animal endocrinology 2019 v.68 pp. 11-24
ISSN:
0739-7240
Subject:
endocrine system,   etc   ; Western blotting; dose response; endometrium; enzyme-linked immunosorbent assay; estradiol; estrone; estrous cycle; gene expression; genes; metabolism; neuropeptides; pregnancy; protein content; quantitative polymerase chain reaction; receptors; secretion; swine;     Show all 18 Subjects
Abstract:
... Orexin A and B (OXA, OXB) are hypothalamic neuropeptides acting via two receptors, type 1 (OX1R) and 2 (OX2R). Orexins, also known as hypocretins, take part in a common endocrine system regulating metabolism and reproductive functions. Changes in the orexin system expression during the estrous cycle and pregnancy suggest dependence on the local hormonal milieu. Estrogens are the key hormones contr ...
DOI:
10.1016/j.domaniend.2018.12.008

8. Manganese exposure and association with hormone imbalance in children living near a ferro-manganese alloy plant

Author:
dos Santos, Nathália R.; Rodrigues, Juliana L.G.; Bandeira, Matheus J.; Anjos, Ana Laura dos S.; Araújo, Cecília de Freitas S.; Adan, Luis Fernando.F.; Menezes-Filho, José A.
Source:
Environmental research 2019 v.172 pp. 166-174
ISSN:
0013-9351
Subject:
endocrine system,   etc   ; alloys; atomic absorption spectrometry; biomarkers; blood; blood sampling; boys; chemiluminescence; dust; elementary schools; environmental exposure; estradiol; humans; lead; luteinizing hormone; manganese; prolactin; puberty; reproductive system; school children; secretion; testosterone; thyrotropin; Brazil;     Show all 24 Subjects
Abstract:
... It has been suggested that manganese (Mn) plays a fundamental role in the reproductive system through interference with the regulation of the secretion of hormones related to puberty. The objective of this study was to evaluate the environmental exposure to Mn and its effects on the endocrine regulation of hormones related to puberty in school-aged children living near a ferro-manganese alloy plan ...
DOI:
10.1016/j.envres.2019.02.021

9. Freshwater snail Parafossarulus striatulus estrogen receptor: Characteristics and expression profiles under lab and field exposure

Author:
Ma, Fujun; Han, Xuemei; An, Lihui; Lei, Kun; Qi, Hongli; LeBlanc, Gerald A.
Source:
Chemosphere 2019 v.220 pp. 611-619
ISSN:
0045-6535
Subject:
endocrine system,   etc   ; DNA-binding domains; amino acids; complementary DNA; endocrine-disrupting chemicals; environmental factors; estradiol; estrogen receptors; females; freshwater; lakes; males; mechanism of action; methyltestosterone; open reading frames; phylogeny; snails; toxicity; vitellogenin; China;     Show all 20 Subjects
Abstract:
... The modes of action by which putative endocrine disrupting chemicals (EDCs) elicit toxicity in mollusks remains unclear due to our limited understanding of the molluscan endocrine system. We identified and partially characterised the estrogen receptor (ER) of the mollusk Parafossarulus striatulus. The full-length cDNA of the ER of P. striatulus (psER) was isolated and found to have an ORF of 1386 ...
DOI:
10.1016/j.chemosphere.2018.12.176

10. Assessing the presence of endocrine disruptors and markers of anthropogenic activity in a water supply system in northeastern Brazil

Author:
Maynard, Isabella Ferreira Nascimento; Cavalcanti, Eliane Bezerra; da Silva, Larissa Limeira; Martins, Elâine Arantes Jardim; Pires, Maria Aparecida Faustino; de Barros, Marcelo Lima; Cardoso, Eni; Marques, Maria Nogueira
Source:
Journal of environmental science and health 2019 v.54 no.9 pp. 891-898
ISSN:
1532-4117
Subject:
endocrine system,   etc   ; androstanes; anthropogenic activities; aquatic ecosystems; aquatic organisms; bisphenol A; caffeine; cholesterol; coprostanol; dibutyl phthalate; diethyl phthalate; endocrine-disrupting chemicals; estradiol; estrone; human health; nonylphenols; pentachlorophenol; pollutants; progesterone; public health; public policy; risk; solid phase extraction; spectrometers; water supply; Brazil;     Show all 26 Subjects
Abstract:
... Several chemical substances known as micropollutants are used in daily activities, and they pose risks to both human health and the environment. Some of these substances disrupt the endocrine system in addition to being responsible for major public health issues and for endangering some aquatic species. The aim of this research is to investigate the frequency of endocrine disruptors and anthropoge ...
DOI:
10.1080/10934529.2019.1606574

11. Quantitative analysis of in-vivo responses of reproductive and thyroid endpoints in male goldfish exposed to monocrotophos pesticide Toxicology & pharmacology

Author:
Zhang, Xiaona; Liu, Wei; Wang, Jun; Tian, Hua; Wang, Wei; Ru, Shaoguo
Source:
Comparative biochemistry and physiology 2018 v.211 pp. 41-47
ISSN:
1532-0456
Subject:
endocrine system,   etc   ; Carassius auratus; adverse outcome pathways; correlation; data analysis; estradiol; genes; goldfish; males; monocrotophos; quantitative analysis; regression analysis; thyroid hormones; transcription (genetics);     Show all 14 Subjects
Abstract:
... Cross-regulation occurs at many points between the hypothalamic-pituitary-gonad (HPG) and hypothalamic-pituitary-thyroid (HPT) axes. Monocrotophos (MCP) pesticide could disrupt HPG and HPT axes, but its direct target within the endocrine system is still unclear. In the present study, hormone concentrations and transcriptional profiles of HPG and HPT genes were examined in male goldfish (Carassius ...
DOI:
10.1016/j.cbpc.2018.05.010

12. Bacteria enhanced lignocellulosic activated carbon for biofiltration of bisphenols in water

Author:
Sarma, Hemen; Lee, Wen-Yee
Source:
Environmental science and pollution research international 2018 v.25 no.18 pp. 17227-17239
ISSN:
0944-1344
Subject:
endocrine system,   etc   ; activated carbon; bacteria; biofiltration; bisphenol A; drinking water; ecosystems; estradiol; estrogen receptors; estrogenic properties; lignocellulose; surface water; toxicity; water utilities; China; India; Japan; Korean Peninsula;     Show all 18 Subjects
Abstract:
... There are eight bisphenol analogues being identified and characterized; among them, bisphenol A (BPA) is on the priority list on the basis of its higher level of uses, occurrence, and toxicity. The endocrine system interfered by BPA has been inventoried as it has the same function as the natural hormone 17β-estradiol and binds mainly to the estrogen receptor (ER) to exhibit estrogenic activities. ...
DOI:
10.1007/s11356-018-2232-7

13. Molecular Mechanism of Binding between 17β-Estradiol and DNA

Author:
Hilder, Tamsyn A.; Hodgkiss, Justin M.
Source:
Computational and Structural Biotechnology Journal 2017 v.15 pp. 91-97
ISSN:
2001-0370
Subject:
endocrine system,   etc   ; DNA; DNA damage; adverse effects; biotechnology; breast neoplasms; chemical elements; estradiol; estrogen receptors; mass spectrometry; molecular dynamics;     Show all 11 Subjects
Abstract:
... Although 17β-estradiol (E2) is a natural molecule involved in the endocrine system, its widespread use in various applications has resulted in its accumulation in the environment and its classification as an endocrine-disrupting molecule. These molecules can interfere with the hormonal system, and have been linked to various adverse effects such as the proliferation of breast cancer. It has been p ...
DOI:
10.1016/j.csbj.2016.12.001
PubMed:
28066533
PubMed Central:
PMC5196241

14. Occurrence and estrogenic activity of steroid hormones in Chinese streams: A nationwide study based on a combination of chemical and biological tools

Author:
Yao, Bo; Li, Rui; Yan, Shuwen; Chan, Shen-An; Song, Weihua
Source:
Environment international 2018 v.118 pp. 1-8
ISSN:
0160-4120
Subject:
endocrine system,   etc   ; aquatic environment; aquatic organisms; coasts; estradiol; estriol; estrogenic properties; estrone; humans; reproduction; risk; rivers; rural areas; sewage; solid phase extraction; steam; steroid hormones; streams; surface water; wastewater; yeasts; China;     Show all 22 Subjects
Abstract:
... Steroid hormones (SHs) are continuously released into the aquatic environment through various pathways after being excreted by humans and animals, interfere with the normal function of the endocrine system and may affect the physiology and reproduction of exposed aquatic life. To conduct a nationwide investigation of the occurrence and biological effects of SHs in surface river/steam water in Chin ...
DOI:
10.1016/j.envint.2018.05.026

15. Summary of the development the US Environmental Protection Agency's Medaka Extended One Generation Reproduction Test (MEOGRT) using data from 9 multigenerational medaka tests

Author:
Flynn, Kevin; Lothenbach, Doug; Whiteman, Frank; Hammermeister, Dean; Touart, Leslie W.; Swintek, Joe; Tatarazako, Norihisa; Onishi, Yuta; Iguchi, Taisen; Johnson, Rodney
Source:
Environmental toxicology and chemistry 2017 v.36 no.12 pp. 3387-3403
ISSN:
0730-7268
Subject:
endocrine system,   etc   ; DDT (pesticide); United States Environmental Protection Agency; adverse effects; dose response; endocrine-disrupting chemicals; estradiol; guidelines; periodicals; pollution; prochloraz; reproductive toxicology; screening; tamoxifen; vinclozolin; United States;     Show all 16 Subjects
Abstract:
... In response to various legislative mandates, the US Environmental Protection Agency (USEPA) formed its Endocrine Disruptor Screening Program (EDSP), which in turn, formed the basis of a tiered testing strategy to determine the potential of pesticides, commercial chemicals, and environmental contaminants to disrupt the endocrine system. The first tier of tests is intended to detect the potential fo ...
DOI:
10.1002/etc.3923

16. Detection of endocrine disrupting chemicals and evidence of their effects on the HPG axis of the European anchovy Engraulis encrasicolus

Author:
Miccoli, Andrea; Maradonna, Francesca; De Felice, Andrea; Caputo Barucchi, Vincenzo; Estonba, Andone; Genangeli, Michele; Vittori, Sauro; Leonori, Iole; Carnevali, Oliana
Source:
Marine environmental research 2017 v.127 pp. 137-147
ISSN:
0141-1136
Subject:
endocrine system,   etc   ; Engraulis encrasicolus; additive effect; anchovies; endocrine-disrupting chemicals; estradiol; estrogenic properties; genes; polychlorinated biphenyls; predators; transcription (genetics); vitellogenin; xenobiotics; Adriatic Sea;     Show all 14 Subjects
Abstract:
... Natural/synthetic Endocrine Disrupting Chemicals (EDCs) may display estrogenic activity and a lower potency than 17β-estradiol. Nonetheless, their concentrations and additive effects can affect the endocrine system and reproductive processes related to the Hypothalamic–Pituitary–Gonadal (HPG) axis. Because of their persistence in both the environment and biological systems, they ultimately target ...
DOI:
10.1016/j.marenvres.2017.04.006

17. Biodegradation of 17β-estradiol by bacteria isolated from deep sea sediments in aerobic and anaerobic media

Author:
Fernández, Lucía; Louvado, António; Esteves, Valdemar I.; Gomes, Newton C.M.; Almeida, Adelaide; Cunha, Ângela
Source:
Journal of hazardous materials 2017 v.323 pp. 359-366
ISSN:
0304-3894
Subject:
endocrine system,   etc   ; Bacillus flexus; Bacillus licheniformis; Virgibacillus; anaerobic conditions; bacteria; biodegradation; endocrine-disrupting chemicals; environmental health; estradiol; estrone; marine sediments; nucleotide sequences; ribosomal DNA; volcanoes; wastewater treatment;     Show all 16 Subjects
Abstract:
... Endocrine disrupting compounds (EDCs) are considered as high research priority being a source of potential adverse ecological health effects in environmental waters. 17β-Estradiol (E2), a recalcitrant natural estrogen, is typically encountered in wastewater treatment plants (WWTPs) at levels ranging 10–30ngL⁻¹ in the influent flow and 1–3ngL⁻¹ in the effluent flow. The exposure to even extremely l ...
DOI:
10.1016/j.jhazmat.2016.05.029

18. Development of QSAR models for predicting the binding affinity of endocrine disrupting chemicals to eight fish estrogen receptor

Author:
He, Junyi; Peng, Tao; Yang, Xianhai; Liu, Huihui
Source:
Ecotoxicology and environmental safety 2017
ISSN:
0147-6513
Subject:
endocrine system,   etc   ; Cypriniformes; Perciformes; Salmoniformes; binding capacity; endocrine-disrupting chemicals; estradiol; estrogen receptors; fish; models; prediction; quantitative structure-activity relationships; sex hormone-binding globulin; species diversity;     Show all 14 Subjects
Abstract:
... Endocrine disrupting effect has become a central point of concern, and various biological mechanisms involve in the disruption of endocrine system. Recently, we have explored the mechanism of disrupting hormonal transport protein, through the binding affinity of sex hormone-binding globulin in different fish species. This study, serving as a companion article, focused on the mechanism of activatin ...
DOI:
10.1016/j.ecoenv.2017.10.023

19. Nanomaterial-based Aptasensors and bioaffinity sensors for quantitative detection of 17β-estradiol

Author:
Nezami, Alireza; Nosrati, Rahim; Golichenari, Behrouz; Rezaee, Ramin; Chatzidakis, Georgios I.; Tsatsakis, Aristides M.; Karimi, Gholamreza
Source:
Trends in analytical chemistry 2017
ISSN:
0165-9936
Subject:
endocrine system,   etc   ; adverse effects; aptasensors; estradiol; gas chromatography; high performance liquid chromatography; mass spectrometry; monitoring; oligonucleotides; quantitative analysis; reproduction; solvents; steroids;     Show all 13 Subjects
Abstract:
... One of the most important endogenous estrogens is 17β-estradiol, which disturbed the endocrine system, and causing adverse effects on the growth, reproduction and development of the body. It is necessary to develop a convenient and rapid analytical method to detect estradiol with high sensitivity and selectivity. For determination of 17β-estradiol, methods such as high performance liquid chromatog ...
DOI:
10.1016/j.trac.2017.07.003

20. Transformation of 17β-estradiol in humic acid solution by ε-MnO2 nanorods as probed by high-resolution mass spectrometry combined with 13C labeling

Author:
Sun, Kai; Liang, Shangtao; Kang, Fuxing; Gao, Yanzheng; Huang, Qingguo
Source:
Environmental pollution 2016 v.214 pp. 211-218
ISSN:
0269-7491
Subject:
endocrine system,   etc   ; aqueous solutions; chemical elements; estradiol; estrone; gel chromatography; humans; humic acids; mass spectrometry; nanorods; oxidation; wildlife;     Show all 12 Subjects
Abstract:
... Steroidal estrogens (SEs), widespread in aquatic systems, have a potential to disrupt the endocrine system of wildlife species and humans. In our experiments, the performance of ε-MnO2 nanorods in transforming 17β-estradiol (E2) was investigated, and the effect of humic acid (HA) on the reaction behaviors was systematically characterized. Reconfiguration of humic molecules was also investigated by ...
DOI:
10.1016/j.envpol.2016.04.021