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- Author:
- Hengjie Su; Tomoko Fujiwara; Joel D. Bumgardner
- Source:
- Marine drugs 2021 v.19 no.3 pp. -
- ISSN:
- 1660-3397
- Subject:
- Fourier transform infrared spectroscopy; bioactive properties; biocompatibility; chitosan; collagen; contact angle; elastin; extracellular matrix; fibroblasts; hydrophobicity; lysozyme; nanofibers; strength (mechanics)
- Abstract:
- ... While electrospun chitosan membranes modified to retain nanofibrous morphology have shown promise for use in guided bone regeneration applications in in vitro and in vivo studies, their mechanical tear strengths are lower than commercial collagen membranes. Elastin, a natural component of the extracellular matrix, is a protein with extensive elastic property. This work examined the incorporation o ...
- DOI:
- 10.3390/md19030169
- https://doi.org/10.3390/md19030169
- Author:
- Ziyu Huang; Yingying Lin; Fazheng Ren; Sijia Song; Huiyuan Guo
- Source:
- Food control 2019 v.105 pp. 13-20
- ISSN:
- 0956-7135
- Subject:
- Bacillus cereus; DNA; antimicrobial properties; biofilm; cleaning in place; confocal laser scanning microscopy; contact angle; dairy industry; detection limit; electrolyte leakage; electrostatic interactions; extracellular matrix; food pathogens; hydrophilicity; microstructure; minimum inhibitory concentration; nitric acid; polysaccharides; proteins; sodium hydroxide; stainless steel; zeta potential
- Abstract:
- ... Bacillus cereus is a common foodborne pathogen in dairy environment, which is hard to remove for its strong biofilm forming ability. In our study, Clean-in-place (CIP) regime and benzalkonium bromide (BK) were used in combination to enhance biofilm removal effectiveness. The CIP regime (1.5% NaOH at 65 °C for 10 min-water rinse-1% HNO3 at 65 °C for 10 min-water rinse) often used in dairy industry ...
- DOI:
- 10.1016/j.foodcont.2019.05.017
- https://doi.org/10.1016/j.foodcont.2019.05.017
- Author:
- Ding Cao; Yi-Pan Wu; Zhi-Feng Fu; Yuan Tian; Cong-Ju Li; Chun-Ying Gao; Zhong-Liang Chen; Xi-Zeng Feng
- Source:
- Colloids and surfaces 2011 v.84 no.1 pp. 26-34
- ISSN:
- 0927-7765
- Subject:
- 4',6-diamidino-2-phenylindole; Fourier transform infrared spectroscopy; X-ray photoelectron spectroscopy; biocompatibility; biocomposites; cell viability; collagen; colloids; contact angle; extracellular matrix; fluorescein; hydroxyapatite; propidium; scanning electron microscopy; tissue engineering
- Abstract:
- ... Nanostructured biocomposite scaffolds of poly(l-lactide) (PLLA) blended with collagen (coll) or hydroxyapatite (HA), or both for tissue engineering application, were fabricated by electrospinning. The electrospun scaffolds were characterized for the morphology, chemical and tensile properties by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), water contact angle (WCA), ...
- DOI:
- 10.1016/j.colsurfb.2010.12.005
- https://doi.org/10.1016/j.colsurfb.2010.12.005
- Author:
- P. Sanmartín; F. Villa; F. Cappitelli; S. Balboa; R. Carballeira
- Source:
- International biodeterioration & biodegradation 2020 v.147 pp. 104871
- ISSN:
- 0964-8305
- Subject:
- X-ray diffraction; aesthetics; algae; biodegradation; biofilm; chemical composition; condensation (phase transition); contact angle; extracellular matrix; granite; hydrophobicity; light microscopy; microclimate; polymers; Spain
- Abstract:
- ... The upper zone of the background walls of the processional cloister of the Monastery of San Martiño Pinario (Santiago de Compostela, Galicia, Spain) is affected by a deep green, highly hydrophobic subaerial biofilm. The pattern that the biofilm follows the walls suggests that particular microclimatic conditions induce changes in the biofilm properties. To test this hypothesis, taxonomic and struct ...
- DOI:
- 10.1016/j.ibiod.2019.104871
- https://doi.org/10.1016/j.ibiod.2019.104871
- Author:
- Sara Mauquoy; Christine Dupont-Gillain
- Source:
- Colloids and surfaces 2016 v.147 pp. 54-64
- ISSN:
- 0927-7765
- Subject:
- adsorption; atomic force microscopy; biomimetics; buffers; collagen; colloids; contact angle; electrolytes; extracellular matrix; fibronectins; pH; polystyrenes; quartz; water content
- Abstract:
- ... Layer-by-layer (LbL) assembly is a surface modification method which may bring complexity to biointerfaces designed to control cell-material interactions. This work aims at investigating the LbL assembly of two extracellular matrix proteins, collagen (Col) and fibronectin (Fn), on polystyrene substrates. LbL assembly, which is widely applied to polyelectrolytes, is not easily transferred to protei ...
- DOI:
- 10.1016/j.colsurfb.2016.07.038
- https://doi.org/10.1016/j.colsurfb.2016.07.038
- Author:
- Wevernilson F. de Deus; Bruna M. de França; Josué Sebastian B. Forero; Alessandro E. C. Granato; Henning Ulrich; Anelise C. O. C. Dória; Marcello M. Amaral; Adam Slabon; Bruno V. M. Rodrigues
- Source:
- ACS applied materials & interfaces 2021 v.13 no.21 pp. 24493-24504
- ISSN:
- 1944-8252
- Subject:
- Gibbs free energy; bioactive properties; cell adhesion; contact angle; curcumin; extracellular matrix; fluorescence; hydrophilicity; hydrophobicity; nanofibers; photochemistry; photoluminescence
- Abstract:
- ... The ability of mimicking the extracellular matrix architecture has gained electrospun scaffolds a prominent space into the tissue engineering field. The high surface-to-volume aspect ratio of nanofibers increases their bioactivity while enhancing the bonding strength with the host tissue. Over the years, numerous polyesters, such as poly(lactic acid) (PLA), have been consolidated as excellent matr ...
- DOI:
- 10.1021/acsami.1c05034
- https://doi.org/10.1021/acsami.1c05034
- Author:
- Sunil Kumar Boda; Conrado Aparicio
- Source:
- Biomaterials science 2022 v.10 no.3 pp. 665-677
- ISSN:
- 2047-4849
- Subject:
- X-ray photoelectron spectroscopy; basement membrane; biocompatible materials; chemoattractants; conjugated linoleic acid; contact angle; epithelial cells; extracellular matrix; humans; inducible nitric oxide synthase; inflammation; integrins; keratinocytes; laminin; lipopolysaccharides; macrophages; mice; oxygen; peptides; phenotype; titanium
- Abstract:
- ... Unlike the attachment of soft epithelial skin tissue to penetrating solid natural structures like fingernails and teeth, sealing around percutaneous/permucosal devices such as dental implants is hindered by inflammation and epidermal down growth. Here, we employed a dual keratinocyte-adhesive peptide and anti-inflammatory biomolecule coating on titanium to promote oral epithelial tissue attachment ...
- DOI:
- 10.1039/d1bm01649k
- https://doi.org/10.1039/d1bm01649k
- Author:
- Baoquan Jia; Yutao Li; Bin Yang; Di Xiao; Shengnan Zhang; A. Varada Rajulu; Tetsuo Kondo; Lina Zhang; Jinping Zhou
- Source:
- Cellulose 2013 v.20 no.4 pp. 1911-1923
- ISSN:
- 0969-0239
- Subject:
- biocompatibility; cellulose; cellulose acetate; contact angle; extracellular matrix; myocytes; smooth muscle; vascular tissues; wettability
- Abstract:
- ... To investigate the potential application of microcrystal cellulose (MCC) and cellulose whisker (CW) in the electrospun vascular tissue scaffolds, cellulose acetate (CA) and cellulose composite scaffolds containing MCC and CW were electrospun from CA solutions and deacetylation. Structure and morphology of MCC, CW and the fibrous composite scaffolds were investigated using FT-IR, SEM, TEM and AFM. ...
- DOI:
- 10.1007/s10570-013-9952-0
- https://doi.org/10.1007/s10570-013-9952-0
- Author:
- Carvalho Angela; Pelaez-Vargas Alejandro; Hansford Derek J.; Fernandes Maria H.; Monteiro Fernando J.
- Source:
- Langmuir 2016 v.32 no.4 pp. 1091-1100
- ISSN:
- 1520-5827
- Subject:
- atomic force microscopy; biobased products; bone formation; bones; contact angle; extracellular matrix; humans; mineralization; scanning electron microscopy; silica; stem cells; tissue engineering
- Abstract:
- ... A primary goal in bone tissue engineering is the design of implants that induce controlled, guided, and rapid healing. The events that normally lead to the integration of an implant into bone and determine the performance of the device occur mainly at the tissue–implant interface. Topographical surface modification of a biomaterial might be an efficient tool for inducing stem cell osteogenic diffe ...
- DOI:
- 10.1021/acs.langmuir.5b03955
- https://doi.org/10.1021/acs.langmuir.5b03955
- Author:
- Ning-hua Liu; Jian-feng Pan; Yue-E Miao; Tian-xi Liu; Feng Xu; Hui Sun
- Source:
- Journal of materials science 2014 v.49 no.20 pp. 7253-7262
- ISSN:
- 0022-2461
- Subject:
- cell adhesion; contact angle; extracellular matrix; hydrophilicity; mixing; stem cells; tensile strength; tissue engineering
- Abstract:
- ... For skin tissue engineering, an ideal scaffold should mimic the natural extracellular matrix of the native skin. In this study, we reported a novel elastic sub-micron fiber scaffold blending poly (ε-caprolactone-co-lactide) (PLCL) and Pluronic at different ratios by electrospinning. PLCL and Pluronic were co-electrospun with the ratio of 100/0, 99/1, 95/5, 90/10, 85/15, and 75/25. These scaffolds ...
- DOI:
- 10.1007/s10853-014-8432-8
- https://doi.org/10.1007/s10853-014-8432-8
- Author:
- Minseong Kim; GeunHyung Kim
- Source:
- Carbohydrate polymers 2012 v.90 no.1 pp. 592-601
- ISSN:
- 0144-8617
- Subject:
- Ecklonia; absorption; alkaline phosphatase; bioactive properties; biocompatibility; bones; calcium; cell viability; contact angle; extracellular matrix; growth factors; hydrophilicity; mechanical properties; nanofibers; physical properties; protein content; surface area; tissue engineering; tissue repair; wettability
- Abstract:
- ... Micro/nanofibrous substrates have been widely used for tissue regeneration because of their similarities to extracellular matrix components and their high surface area, which facilitates attachment and proliferation of cells. Phlorotannin, the main component of the brown alga Ecklonia cava, contains various growth factors that promote the regeneration of various tissues, including bone, by stimula ...
- DOI:
- 10.1016/j.carbpol.2012.05.082
- https://doi.org/10.1016/j.carbpol.2012.05.082
- Author:
- Sanaz Behtaj; Fereshteh Karamali; Elahe Masaeli; Yuri G. Anissimov; Maksym Rybachuk
- Source:
- Biochemical engineering journal 2021 v.166 pp. 107846
- ISSN:
- 1369-703X
- Subject:
- Raman spectroscopy; adhesion; biopolymers; cell transplantation; contact angle; extracellular matrix; glycerol; polylactic acid; stem cells
- Abstract:
- ... Recent advances in cell transplantation technologies have shown that polymeric fibrous tissue-engineered scaffolds provide a suitable physical environment, including the structural support, for cell delivery and effectively mimic the transplanted cells’ extracellular matrix. Our study investigates the structure, composition and properties of three most commonly used polyester-based biopolymer mate ...
- DOI:
- 10.1016/j.bej.2020.107846
- https://doi.org/10.1016/j.bej.2020.107846
- Author:
- Tian Zhou; Nanping Wang; Yang Xue; Tingting Ding; Xin Liu; Xiumei Mo; Jiao Sun
- Source:
- Colloids and surfaces 2016 v.143 pp. 415-422
- ISSN:
- 0927-7765
- Subject:
- amino acids; bioactive properties; biocompatible materials; biomimetics; collagen; colloids; contact angle; cost effectiveness; extracellular matrix; gene expression; humans; immunoglobulin G; immunoglobulin M; keratinocytes; lymphocytes; medicine; mice; nanofibers; protein-glutamine gamma-glutamyltransferase; rats; risk; tensile strength; thermal stability; tissue repair
- Abstract:
- ... The development of biomaterials with the ability to induce skin wound healing is a great challenge in biomedicine. In this study, tilapia skin collagen sponge and electrospun nanofibers were developed for wound dressing. The collagen sponge was composed of at least two α-peptides. It did not change the number of spleen-derived lymphocytes in BALB/c mice, the ratio of CD4⁺/CD8⁺ lymphocytes, and the ...
- DOI:
- 10.1016/j.colsurfb.2016.03.052
- https://doi.org/10.1016/j.colsurfb.2016.03.052
- Author:
- Svenja Hinderer; Marianne Schesny; Alexandra Bayrak; Bettina Ibold; Martina Hampel; Thorsten Walles; Ulrich A. Stock; Martina Seifert; Katja Schenke-Layland
- Source:
- Biomaterials 2012 v.33 no.21 pp. 5259-5266
- ISSN:
- 0142-9612
- Subject:
- atomic force microscopy; biocompatible materials; cell adhesion; collagen; connective tissues; contact angle; extracellular matrix; immune response; proteoglycans; scanning electron microscopy; tissue engineering
- Abstract:
- ... Decorin is a structural and functional proteoglycan (PG) residing in the complex network of extracellular matrix (ECM) proteins in many connective tissues. Depending on the protein core and the glycosaminoglycan chain, PGs support cell adhesion, migration, proliferation, differentiation, ECM assembly and growth factor binding. For applications in tissue engineering, it is crucial to develop reliab ...
- DOI:
- 10.1016/j.biomaterials.2012.03.075
- https://doi.org/10.1016/j.biomaterials.2012.03.075
- Author:
- Xin Zhang; Junyu Chen; Xiang Pei; Jian Wang; Qianbing Wan; Shaokang Jiang; Chao Huang; Xibo Pei
- Source:
- ACS applied materials & interfaces 2017 v.9 no.30 pp. 25171-25183
- ISSN:
- 1944-8252
- Subject:
- Fourier transform infrared spectroscopy; X-ray diffraction; bioactive properties; bone formation; collagen; contact angle; crystals; extracellular matrix; gene expression regulation; genes; heat treatment; mice; mineralization; nanomaterials; scanning electron microscopy; secretion; titanium
- Abstract:
- ... Nanoscale zeolitic imidazolate framework-8 (ZIF-8)-modified titanium (ZIF-8@AHT) can enhance osteogenesis in vitro. In this study, we systematically and quantitatively examined the effects of ZIF-8@AHT on osteogenesis, and investigated its ability to form bone in vivo. First, we coated various quantities of nanoscale ZIF-8 crystals on alkali- and heat-treated titanium (AHT) by controlling the conc ...
- DOI:
- 10.1021/acsami.7b07800
- https://doi.org/10.1021/acsami.7b07800
- Author:
- Yanyan Zheng; Lvhua Liu; Ying Ma; Li Xiao; Ying Liu
- Source:
- Industrial & engineering chemistry process design and development 2018 v.57 no.31 pp. 10403-10410
- ISSN:
- 1520-5045
- Subject:
- X-ray photoelectron spectroscopy; alkaline phosphatase; atomic force microscopy; bone formation; cell adhesion; contact angle; dental prosthesis; enzyme activity; extracellular matrix; hydrophilicity; mineralization; modulus of elasticity; orthopedics; osteoblasts; polymerization; process design; quantitative polymerase chain reaction; roughness; topology; viability assays
- Abstract:
- ... Polyetheretherketone (PEEK) has the potential to replace traditional metallic materials as an orthopedic and dental implant because its elastic modulus is similar to natural bone, although its intrinsic bioinertness hampers its clinical application. In this study, sulfonate groups were introduced onto the PEEK surface through a single-step ultraviolet-initiated graft polymerization of vinylsulfoni ...
- DOI:
- 10.1021/acs.iecr.8b02158
- https://doi.org/10.1021/acs.iecr.8b02158
- Author:
- Yanyan Zheng; Lvhua Liu; Li Xiao; Qianyu Zhang; Ying Liu
- Source:
- Colloids and surfaces 2019 v.173 pp. 591-598
- ISSN:
- 0927-7765
- Subject:
- X-ray photoelectron spectroscopy; adhesion; alkaline phosphatase; atomic force microscopy; bone formation; cell adhesion; colloids; contact angle; dental prosthesis; enzyme activity; extracellular matrix; histology; mineralization; models; modulus of elasticity; orthopedics; osteoblasts; phosphates; polymerization; quantitative polymerase chain reaction; rabbits; roughness; tibia
- Abstract:
- ... Polyetheretherketone (PEEK) is considered to be a prime candidate with the potential to replace biomedical metallic materials as an orthopedic and dental implant on account of its elastic modulus similar to that of human cortical bone. Unfortunately, its biomedical application is impeded by the bioinert surface property and inferior osteogenic activity. In this work, phosphate groups were incorpor ...
- DOI:
- 10.1016/j.colsurfb.2018.10.031
- https://doi.org/10.1016/j.colsurfb.2018.10.031
18. Fabrication and characterization of nano-fibrous bilayer composite for skin regeneration application
- Author:
- Shaghayegh Arasteh; Somaieh Kazemnejad; Sayeh Khanjani; Hamed Heidari-Vala; Mohammad Mehdi Akhondi; Sahba Mobini
- Source:
- Methods 2016 v.99 pp. 3-12
- ISSN:
- 1046-2023
- Subject:
- Bombyx mori; cell culture; coatings; cocoons; contact angle; enzymatic treatment; extracellular matrix; fibroblasts; fibroins; fibronectins; humans; hydrophilicity; mice; microstructure; modulus of elasticity; mothers; oxygen; scanning electron microscopy; silk; staining; tensile strength; tissue repair
- Abstract:
- ... Full thickness wound healing with minimal scarring and complete restoration of normal skin properties still remains as a clinical challenge. In this study, a bilayer skin substitute has been fabricated to biomimic the microstructure of natural extracellular matrix of the skin. Human amniotic membrane (HAM) and silk fibroin nano-fibers were combined to produce bilayer construct, which was further t ...
- DOI:
- 10.1016/j.ymeth.2015.08.017
- https://doi.org/10.1016/j.ymeth.2015.08.017
- Author:
- Teng Wang; Yi Wan; Zhanqiang Liu
- Source:
- Journal of materials science 2016 v.51 no.21 pp. 9551-9561
- ISSN:
- 0022-2461
- Subject:
- X-ray diffraction; adhesion; alkaline phosphatase; alloys; bioassays; biocompatible materials; cell adhesion; contact angle; extracellular matrix; heat treatment; hydrophilicity; microstructure; mineralization; nanowires; osteoblasts; osteocalcin; scanning electron microscopes; scanning electron microscopy; titanium
- Abstract:
- ... Micro/nanotopographical modification of biomaterials plays an essential role in the improvement of implants’ cytocompatibility. In this paper, hierarchical micro/nanostructured surface was constructed to improve the titanium alloy cytocompatibility, which combined sandblasting, acid etching, and alkali heat treatment. The surface features were characterized using scanning electron microscope (SEM) ...
- DOI:
- 10.1007/s10853-016-0219-7
- https://doi.org/10.1007/s10853-016-0219-7
- Author:
- Shifeng Yan; Kunxi Zhang; Zhiwen Liu; Xin Zhang; Lu Gan; Bin Cao; Xuesi Chen; Lei Cui; Jingbo Yin
- Source:
- Journal of materials chemistry B 2013 v.1 no.11 pp. 1541-1551
- ISSN:
- 2050-7518
- Subject:
- biocompatibility; biodegradability; biodegradation; cartilage; chitosan; contact angle; electrolytes; extracellular matrix; freeze drying; freezing point; hydrophilicity; in vitro culture; microstructure; polyglutamic acid; polypeptides; porosity; rabbits; stem cells; strength (mechanics); tissue engineering
- Abstract:
- ... Porous scaffolds composed of polypeptides and polysaccharides have remarkable biocompatibility and potential to mimic an extracellular matrix for tissue engineering. This study presented a novel design of polyelectrolyte complex porous scaffolds of a synthetic polypeptide poly(l-glutamic acid) (PLGA) and a natural polysaccharide chitosan (CS) using a freeze drying method. The microstructure of the ...
- DOI:
- 10.1039/c2tb00440b
- https://doi.org/10.1039/c2tb00440b
- Author:
- Shuqin Yan; Qiusheng Wang; Zeeshan Tariq; Renchuan You; Xiufang Li; Mingzhong Li; Qiang Zhang
- Source:
- International journal of biological macromolecules 2018 v.118 pp. 775-782
- ISSN:
- 0141-8130
- Subject:
- biocompatible materials; contact angle; drugs; extracellular matrix; fibroins; hyaluronic acid; hydrogels; hydrophilicity; mechanical properties; porosity; rats; silk; tissue repair; tissues; water uptake
- Abstract:
- ... Proteins and polysaccharides are primary components in mammal soft tissue. In this study, we established a rapid hydrogel to imitate the nature extracellular matrix via silk fibroin (SF) and hyaluronic acid (HA) blend hydrogel. SF/HA hydrogel was prepared effectively, and its formation time was shorted. With the increase of HA content, the water absorption, porosity and breaking strengths of the h ...
- DOI:
- 10.1016/j.ijbiomac.2018.06.138
- https://doi.org/10.1016/j.ijbiomac.2018.06.138
- Author:
- He Xiao-Ling; Ge Li-Li; Liu Ze-Li; Lu Wen-Jia; Li Jia-Quan; Zhao Yue-Mei; Li Xiang-Xu; Yang Ning; Chen Li; Wei Dong-Sheng
- Source:
- Industrial & Engineering Chemistry Research 2014 v.53 no.26 pp. 10618-10628
- ISSN:
- 1520-5045
- Subject:
- adhesion; albumins; cell adhesion; contact angle; extracellular matrix; hepatocytes; hepatoma; human cell lines; hydrogels; hydrophilicity; hydrophobicity; liver; scanning electron microscopy; temperature; tissue engineering; urea
- Abstract:
- ... Glycyrrhetinic acid-based thermoresponsive hydrogels P(NIPAAm-co-GAA) were prepared and used to promote initial cell adhesion, growth, and recovery by lowering temperature for further tissue engineering or bioartificial liver applications. The compositions, morphologies and properties of hydrogels were characterized by element analysis, scanning electron microscopy (SEM), and water contact angle m ...
- DOI:
- 10.1021/ie404417u
- https://doi.org/10.1021/ie404417u
- Author:
- Makarand Risbud; Anandwardhan Hardikar; Ramesh Bhonde
- Source:
- Journal of biosciences 2000 v.25 no.1 pp. 25-30
- ISSN:
- 0250-5991
- Subject:
- adults; chitosan; collagen; contact angle; epithelial cells; epithelium; extracellular matrix; fetus; fibroblasts; hydrogels; hydrophilicity; image analysis; octane; polystyrenes; pyrrolidones; tetrazolium; tissue culture; wound treatment
- Abstract:
- ... Wounds in adults and fetuses differ in their healing ability with respect to scar formation. In adults, wounds lacking the epidermis exhibit excess collagen production and scar formation. Fibroblasts synthesize and deposit a collagen rich extracellular matrix. The early migration and proliferation of fibroblasts in the wound area is implicated in wound scarring. We have synthesized a hydrogel from ...
- DOI:
- 10.1007/BF02985178
- https://doi.org/10.1007/BF02985178
- Author:
- Marziyeh Ranjbar-Mohammadi; Molamma P. Prabhakaran; S. Hajir Bahrami; Seeram Ramakrishna
- Source:
- Carbohydrate polymers 2016 v.140 pp. 104-112
- ISSN:
- 0144-8617
- Subject:
- Fourier transform infrared spectroscopy; biodegradation; cell growth; cell proliferation; contact angle; extracellular matrix; gum tragacanth; mechanical properties; nanofibers; nerve tissue; neurites; polylactic acid; scanning electron microscopes; tissue repair; topography
- Abstract:
- ... Nanofibrous nerve guides have gained huge interest in supporting the peripheral nerve regeneration due to their abilities to simulate the topography, mechanical, biological and extracellular matrix morphology of native tissue. Gum tragacanth (GT) is a biocompatible mixture of polysaccharides that has been used in biomedical applications. During this study, we fabricated aligned and random nanofibe ...
- DOI:
- 10.1016/j.carbpol.2015.12.012
- https://doi.org/10.1016/j.carbpol.2015.12.012
- Author:
- Xinqing Pang; Weiqi Li; Lan Chang; Julien E. Gautrot; Wen Wang; Helena S. Azevedo
- Source:
- ACS applied materials & interfaces 2021 v.13 no.22 pp. 25792-25804
- ISSN:
- 1944-8252
- Subject:
- biomimetics; contact angle; endothelial cells; extracellular matrix; focal adhesions; hyaluronic acid; hydrophilicity; laminar flow; molecular weight; peptides; phenotype
- Abstract:
- ... The extracellular matrix (ECM) modulates a multitude of cell functions, and this regulation is provided by key ECM components forming a complex network. Hyaluronic acid (HA) is an abundant component of the ECM that binds to proteins and influences various activities of endothelial cells (ECs). Although the effect of soluble HA on cell spreading has been studied, the impact of peptide-bound HA has ...
- DOI:
- 10.1021/acsami.1c05574
- https://doi.org/10.1021/acsami.1c05574
- Author:
- Yue Shan; Chaoyue Li; Yongzhi Wu; Qiwen Li; Jinfeng Liao
- Source:
- RSC advances 2019 v.9 no.40 pp. 22966-22979
- ISSN:
- 2046-2069
- Subject:
- biocompatibility; biocompatible materials; biopolymers; calcium; cell adhesion; cell growth; cellulose; collagen; contact angle; crosslinking; cytotoxicity; electrostatic interactions; extracellular matrix; fibroblasts; gelatin; ions; mice; nanocrystals; scanning electron microscopy; sodium alginate; strength (mechanics); tissue repair
- Abstract:
- ... Nature derived biopolymers such as polysaccharides and collagen have attracted considerable attention in biomedical applications. Despite excellent biocompatibility and bioactivity, their poor mechanical properties could not meet the requirement for skin regeneration. In this study, cellulose nanocrystal (CNC) was incorporated into the calcium cross-linked sodium alginate/gelatin (SA/Ge) scaffold ...
- DOI:
- 10.1039/c9ra04026a
- https://doi.org/10.1039/c9ra04026a
- Author:
- Hui Li; Bin’en Nie; Shutao Zhang; Teng Long; Bing Yue
- Source:
- Colloids and surfaces 2019 v.175 pp. 409-420
- ISSN:
- 0927-7765
- Subject:
- X-ray photoelectron spectroscopy; absorption; acid phosphatase; alizarin; alkaline phosphatase; animal models; antibiotics; bioactive properties; biocompatibility; bone formation; bone marrow; coatings; collagen; colloids; contact angle; drug carriers; drugs; extracellular matrix; high performance liquid chromatography; hyaluronic acid; mesenchymal stromal cells; nanotubes; osteoclasts; ovariectomy; prostheses; rats; scanning electron microscopy; staining; titanium dioxide
- Abstract:
- ... Titania nanotubes (Ti-NTs) have been proven to be good drug carriers and can release drugs efficiently around implants. Enoxacin (EN) is a broad-spectrum antibiotic that has the ability of anti-osteoclastogenesis. Immobilization of extracellular matrix components on the surface of the material can greatly enhance the biological activity of the implant and slow down the release rate of the drug in ...
- DOI:
- 10.1016/j.colsurfb.2018.12.033
- https://doi.org/10.1016/j.colsurfb.2018.12.033
- Author:
- Ferreira Ana M.; Gentile Piergiorgio; Toumpaniari Sotiria; Ciardelli Gianluca; Birch Mark A.
- Source:
- ACS applied materials 2016 v.8 no.44 pp. 29923-29932
- ISSN:
- 1944-8252
- Subject:
- coatings; collagen; contact angle; engineering; extracellular matrix; heparin; humans; infrared spectroscopy; polylactic acid; stem cells
- Abstract:
- ... Bone cell interaction with extracellular matrix (ECM) microenvironment is of critical importance when engineering surface interfaces for bone regeneration. In this work layer-by-layer films of type I collagen (coll), the major constituent of bone ECM, and heparin (hep), a glycosaminoglycan, were assembled on poly(l-lactic acid) (PLLA) substrates to evaluate the impact of the biomacromolecular coat ...
- DOI:
- 10.1021/acsami.6b09241
- https://doi.org/10.1021/acsami.6b09241
- Author:
- Kui Xu; Weizhen Chen; Guanglei Fu; Xianbo Mou; Ruixia Hou; Yabin Zhu; Kaiyong Cai
- Source:
- Carbon 2019 v.142 pp. 567-579
- ISSN:
- 0008-6223
- Subject:
- Gibbs free energy; X-ray photoelectron spectroscopy; adhesion; adsorption; atomic force microscopy; body fluids; bone formation; carbon; coatings; contact angle; extracellular matrix; genes; glucose; graphene oxide; ions; mesenchymal stromal cells; mineralization; nanosheets; physicochemical properties; proteins; scanning electron microscopy; strontium; titanium
- Abstract:
- ... Bioinert surface is the greatest obstacle to the biomedical applications of titanium (Ti)-based materials. Herein, a bioactive coating as a carrier of strontium ions (Sr²⁺) on Ti surfaces was prepared by in situ self-assembly of graphene oxide/polydopamine/Sr²⁺ (GO/PDA/Sr²⁺) nanosheets. Surface physicochemical characteristics of the coating were evaluated by scanning electron microscopy (SEM), ato ...
- DOI:
- 10.1016/j.carbon.2018.10.081
- https://doi.org/10.1016/j.carbon.2018.10.081
- Author:
- Zheng Jun; Li Dan; Yuan Lin; Liu Xiaoli; Chen Hong
- Source:
- ACS Applied Materials & Interfaces 2013 v.5 no.12 pp. 5882-5887
- ISSN:
- 1944-8252
- Subject:
- adhesion; adsorption; biodegradability; cell adhesion; contact angle; endothelial cells; enzyme-linked immunosorbent assay; extracellular matrix; fibroblasts; fibronectins; hydrophobicity; polymers; surface interactions; topography
- Abstract:
- ... It is well-known that extracellular matrix (ECM) proteins mediate cell/surface interactions. However, introduction of a specific surface topography may disturb the correlation between ECM proteins adsorption and cells adhesion on a given surface. In present study, lotus-leaf-like topography was introduced on the surface of a biodegradable material, poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PH ...
- DOI:
- 10.1021/am4017329
- https://doi.org/10.1021/am4017329
- Author:
- Roberta Fraioli; Florian Rechenmacher; Stefanie Neubauer; José M. Manero; Javier Gil; Horst Kessler; Carlos Mas-Moruno
- Source:
- Colloids and surfaces 2015 v.128 pp. 191-200
- ISSN:
- 0927-7765
- Subject:
- X-ray photoelectron spectroscopy; adhesion; alkaline phosphatase; bioactive properties; biocompatible materials; biomimetics; bones; cell adhesion; cell proliferation; colloids; contact angle; extracellular matrix; fluorescence emission spectroscopy; fluorescent labeling; integrins; ligands; mineralization; osteoblasts; synthetic products; titanium
- Abstract:
- ... Interaction between the surface of implants and biological tissues is a key aspect of biomaterials research. Apart from fulfilling the non-toxicity and structural requirements, synthetic materials are asked to direct cell response, offering engineered cues that provide specific instructions to cells. This work explores the functionalization of titanium with integrin-binding peptidomimetics as a no ...
- DOI:
- 10.1016/j.colsurfb.2014.12.057
- https://doi.org/10.1016/j.colsurfb.2014.12.057
- Author:
- Vytautas Cėpla; Tomas Rakickas; Gintarė Stankevičienė; Airina Mazėtytė-Godienė; Aušra Baradokė; Živilė Ruželė; Ramu̅nas Valiokas
- Source:
- ACS applied materials & interfaces 2020 v.12 no.29 pp. 32233-32246
- ISSN:
- 1944-8252
- Subject:
- atomic force microscopy; cell culture; coatings; contact angle; extracellular matrix; fibronectins; glass; hydrogels; image analysis; pH; photochemical reactions; polyethylene glycol; polymerization; protein binding; ultraviolet radiation
- Abstract:
- ... An efficient procedure for chemical initiator-free, in situ synthesis of a functional polyethylene glycol methacrylate (PEG MA) hydrogel on regular glass substrates is reported. It is demonstrated that self-initiated photografting and photopolymerization driven by UV irradiation can yield tens of nanometer-thick coatings of carboxy-functionalized PEG MA on the aldehyde-terminated borosilicate glas ...
- DOI:
- 10.1021/acsami.0c04085
- https://doi.org/10.1021/acsami.0c04085
- Author:
- Travan Andrea; Marsich Eleonora; Donati Ivan; Foulc Marie-Pierre; Moritz Niko; Aro Hannu T.; Paoletti Sergio
- Source:
- Biomacromolecules 2012 v.13 no.5 pp. 1564-1572
- ISSN:
- 1526-4602
- Subject:
- alkaline phosphatase; alloys; biocompatibility; bisphenol A; cell proliferation; coatings; contact angle; extracellular matrix; hardness; hydrophilicity; in vivo studies; ionic strength; mechanical properties; miniature swine; orthopedics; osteoblasts; pH; polymers; polysaccharides; prostheses; titanium
- Abstract:
- ... The long-term stability and success of orthopedic implants depend on the osseointegration process, which is strongly influenced by the biomaterial surface. A promising approach to enhance implant integration involves the modification of the surface of the implant by means of polymers that mimic the natural components of the extracellular matrix, for example, polysaccharides. In this study, methacr ...
- DOI:
- 10.1021/bm3002683
- https://doi.org/10.1021/bm3002683
- Author:
- Rongjun Li; Yali Ma; Yan Zhang; Mei Zhang; Dahui Sun
- Source:
- Colloids and surfaces 2018 v.169 pp. 384-394
- ISSN:
- 0927-7765
- Subject:
- Western blotting; alizarin; bioactive properties; bone formation; bone morphogenetic proteins; bones; contact angle; dexamethasone; extracellular matrix; fluorescent antibody technique; hydrophilicity; in vitro studies; nanofibers; scanning electron microscopy; staining; stem cells; tissue engineering; transmission electron microscopy; viability; zein
- Abstract:
- ... Nanofibers fabricated by electrospinning simulate the extracellular matrix of bone cells and so researchers have taken a keen interest in them for regenerating bone tissue. The aim of this study was to fabricate ideal Zein/PLLA nanofibers by coaxial electrospinning and to load them with bone morphogenetic protein 2 (BMP-2) and dexamethasone (DEX) for dual controlled-release for bone tissue enginee ...
- DOI:
- 10.1016/j.colsurfb.2018.05.039
- https://doi.org/10.1016/j.colsurfb.2018.05.039
- Author:
- Parisa Ahmadi; Niloofar Nazeri; Mohammad Ali Derakhshan; Hossein Ghanbari
- Source:
- International journal of biological macromolecules 2021 v.180 pp. 590-598
- ISSN:
- 0141-8130
- Subject:
- X-ray diffraction; acetic acid; biocompatibility; cardiomyocytes; cell viability; chitosan; contact angle; electrical resistance; extracellular matrix; heart failure; myocardial infarction; nanofibers; polyurethanes; transmission electron microscopy; viability assays
- Abstract:
- ... Myocardial infarction of cardiomyocytes is a leading cause of heart failure (HF) worldwide. Since heart has very limited regeneration capacity, cardiac tissue engineering (TE) to produce a bioactive scaffold is considered. In this study, a series of polyurethane solutions (5–7%wt) in aqueous acetic acid were prepared using electrospinning. A variety of Polyurethane (PU)/Chitosan (Cs)/carbon nanotu ...
- DOI:
- 10.1016/j.ijbiomac.2021.03.001
- https://doi.org/10.1016/j.ijbiomac.2021.03.001
- Author:
- Dandan Guo; Shuai Wang; Yuxiang Yin; Jun Luo; Chenjie Meng; Qingsheng Liu; Haiyan Ni; Jianyong Feng
- Source:
- Textile research journal 2020 v.90 no.7-8 pp. 925-936
- ISSN:
- 1746-7748
- Subject:
- cell proliferation; collagen; contact angle; extracellular matrix; knitted fabrics; lactones; myocardium; nerve tissue; permeability; polyurethanes; textile fibers; thermal conductivity; tissue engineering; tissue repair; woven fabrics
- Abstract:
- ... The extracellular matrix (ECM), with its multilayer fiber structure, regulates diverse functions including cell proliferation, migration, differentiation and tissue regeneration effects. To mimic and replace the native ECM, the structures and properties of three single-layer fabric substrates including warp/weft-knitted and woven fabrics were analyzed, then two-layer warp/weft-knitted composite fa ...
- DOI:
- 10.1177/0040517519883958
- https://doi.org/10.1177/0040517519883958
37. Responses of human gingival fibroblasts to superhydrophilic hydrogenated titanium dioxide nanotubes
- Author:
- Caiyun Wang; Xin Wang; Ran Lu; Shang Gao; Yunhan Ling; Su Chen
- Source:
- Colloids and surfaces 2021 v.198 pp. 111489
- ISSN:
- 0927-7765
- Subject:
- adhesion; bioactive properties; cell adhesion; cell structures; contact angle; extracellular matrix; fibroblasts; gene expression; humans; hydrogenation; hydrophilicity; immunocytochemistry; nanotubes; non-specific protein-tyrosine kinase; quantitative polymerase chain reaction; tissue repair; titanium; titanium dioxide; wettability
- Abstract:
- ... Soft tissue integration is critical for the long-term retention of dental implants. The surface properties including topography and wettability can impact soft tissue sealing. In our work, a thermal hydrogenation technique was applied to modify anodized titanium dioxide nanotubes (TNTs). However, the effects of the hydrogenated surface on soft-tissue cells remain unclear. The aim of the present st ...
- DOI:
- 10.1016/j.colsurfb.2020.111489
- https://doi.org/10.1016/j.colsurfb.2020.111489
- Author:
- Sarah Yahia; Islam A. Khalil; Ibrahim M. El-Sherbiny
- Source:
- ACS applied materials & interfaces 2019 v.11 no.32 pp. 28610-28620
- ISSN:
- 1944-8252
- Subject:
- Fourier transform infrared spectroscopy; animal models; apatite; biocompatible materials; body fluids; bone formation; bone fractures; calcium; cell viability; chitosan; contact angle; differential scanning calorimetry; extracellular matrix; hydrophilicity; ions; lactones; mandible (bone); mechanical properties; mesenchymal stromal cells; modulus of elasticity; nanofibers; phosphorus; polyethylene glycol; rabbits; scanning electron microscopy; thermal stability; thermogravimetry; tissue repair
- Abstract:
- ... Advanced bone healing approaches included a wide range of biomaterials that mainly mimic the composition, structure, and properties of bone extracellular matrix with osteogenic activity. The present study aimed to develop a sandwich-like structure of electrospun nanofibers (NFs) based on polycaprolactone (PCL) and chitosan/polyethylene oxide (CS/PEO) composite to stimulate bone fracture healing. T ...
- DOI:
- 10.1021/acsami.9b06359
- https://doi.org/10.1021/acsami.9b06359
- Author:
- Matsuno Hisao; Ohta Toshiyuki; Shundo Atsuomi; Fukunaga Yasuo; Tanaka Keiji
- Source:
- Langmuir 2014 v.30 no.50 pp. 15238-15243
- ISSN:
- 1520-5827
- Subject:
- X-ray photoelectron spectroscopy; adsorption; ambient temperature; atomic force microscopy; cell adhesion; cell culture; chemical composition; contact angle; denaturation; diameter; extracellular matrix; fibroblasts; fibronectins; hydrophobicity; nanobubbles; polystyrenes; wettability
- Abstract:
- ... We propose a novel method to treat polymeric scaffold surfaces for cell culture with water containing nanobubbles, called ultrafine bubbles (UFBs), with typical diameters less than 1 μm. A thin film of polystyrene (PS) prepared on a solid substrate was exposed to UFB water for 2 days at room temperature. The PS surface was characterized by X-ray photoelectron spectroscopy (XPS), static contact ang ...
- DOI:
- 10.1021/la5035883
- https://doi.org/10.1021/la5035883
- Author:
- Cai Zhijiang; Xiong Ping; He Shiqi; Zhu Cong
- Source:
- Cellulose 2019 v.26 no.10 pp. 6133-6150
- ISSN:
- 0969-0239
- Subject:
- Fourier transform infrared spectroscopy; X-ray diffraction; biocompatibility; biodegradability; biodegradation; bones; cellulose; contact angle; crystal structure; energy-dispersive X-ray analysis; extracellular matrix; hydrophilicity; in vitro studies; mechanical properties; nanofibers; nanoparticles; scanning electron microscopy; soy protein; thermal stability; thermogravimetry; tissue engineering
- Abstract:
- ... Protein-modified scaffolds have ability to provide biological functionality due to the similarity in structure of natural extracellular matrix (NECM) in tissues. In this paper, soy protein was selected to modify bacterial cellulose (BC) electrospun nanofiber scaffold prepared by fabricating BC nanofiber via electrospinning followed by ultrasound-induced self-assembly method. The modified nanofiber ...
- DOI:
- 10.1007/s10570-019-02513-x
- https://doi.org/10.1007/s10570-019-02513-x
- Author:
- Li Hai; Xia Yun; Wu Jumiati; He Qiyuan; Zhou Xiaozhu; Lu Gang; Shang Lei; Boey Freddy; Venkatraman Subbu S.; Zhang Hua
- Source:
- ACS Applied Materials & Interfaces 2012 v.4 no.2 pp. 687-693
- ISSN:
- 1944-8252
- Subject:
- aldehydes; atomic force microscopy; cell proliferation; confocal laser scanning microscopy; contact angle; drugs; epoxides; extracellular matrix; focal adhesions; gelatin; human umbilical vein endothelial cells; oxygen; polylactic acid
- Abstract:
- ... Poly(l-lactic acid) (PLLA) is widely used in drug delivery and medical implants. Surface modification of PLLA with functional groups to immobilize gelatin or other extracellular matrix proteins is commonly used to improve its cellular affinity. In this work, we use the oxygen plasma to treat PLLA film followed by modification with organosilanes with different functional groups, such as amine, epox ...
- DOI:
- 10.1021/am201795g
- https://doi.org/10.1021/am201795g
- Author:
- Lvhua Liu; Yanyan Zheng; Qianyu Zhang; Lin Yu; Ziliang Hu; Ying Liu
- Source:
- RSC advances 2019 v.9 no.52 pp. 30076-30086
- ISSN:
- 2046-2069
- Subject:
- X-ray photoelectron spectroscopy; adhesion; alkaline phosphatase; atomic force microscopy; bioactive properties; biological assessment; biomechanics; bone formation; collagen; contact angle; dental prosthesis; dose response; enzyme activity; extracellular matrix; femur; gene expression; histology; mineralization; models; modulus of elasticity; orthopedics; osteoblasts; phosphonates; polymerization; rats; roughness; secretion
- Abstract:
- ... Polyetheretherketone (PEEK) is a promising alternative for biomedical metallic implants in orthopedic and dental applications because its elastic modulus is similar to that of bone. However, PEEK is a bioinert material that cannot be integrated with host bone. Our previous study showed surface phosphonation enhanced the osteogenic activity of PEEK. The purpose of this study was to evaluate the eff ...
- DOI:
- 10.1039/c9ra05229a
- https://doi.org/10.1039/c9ra05229a
- Author:
- Federica Recupido; Giuseppe Toscano; Rosarita Tatè; Maria Petala; Sergio Caserta; Thodoris D. Karapantsios; Stefano Guido
- Source:
- Colloids and surfaces 2020 v.192 pp. 111047
- ISSN:
- 0927-7765
- Subject:
- Pseudomonas fluorescens; bacterial communities; biofilm; contact angle; extracellular matrix; glass; laminar flow; mass transfer
- Abstract:
- ... Biofilms are bacterial communities embedded in an extracellular matrix, able to adhere to surfaces. Different experimental set-ups are widely used for in vitro biofilm cultivation; however, a well-defined comparison among different culture conditions, especially suited to interfacial characterization, is still lacking in the literature. The main objective of this work is to study the role of flow ...
- DOI:
- 10.1016/j.colsurfb.2020.111047
- https://doi.org/10.1016/j.colsurfb.2020.111047