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... In this paper, polysaccharides from Agrocybe cylindracea (ACPs) were chemically acetylated. Effects of reaction time, reaction temperature and acetylated reagent amounts (acetic anhydride) on the degree of substitution (DS) of acetylated groups were investigated based on single factor experiments. Response surface analysis method was used to optimize acetylation process of ACPs. The maximum DS of ...
... BACKGROUND: In the recent epoch, chitinolytic enzymes have attained much attention as promising biocontrol agents and ability to convert recalcitrant chitinous wastes into valuable products. Some chitinolytic microorganisms have emerged as the potential candidate to carry a noticeable ability to degrade this polysaccharide in nature. OBJECTIVE: Therefore, in this study, a new bacterial strain Acin ...
carcinogenicity; chronic exposure; cytotoxicity; food additives; hydroquinone; mechanism of action; mutagens; public health; safety assessment; therapeutics; toxicology
Abstract:
... Tert-butyl hydroquinone (TBHQ) is a food additive commonly used as a more effective protectant in the food, cosmetic and pharmaceutical industries. However, the long-term exposure to TBHQ at higher doses (0.7 mg/kg) results in substantial danger to public health and brings a series of side effects, including cytotoxic, genotoxic, carcinogenic, and mutagenic effects. As a result, the global burden ...
... Aluminum sulfate (AlS), a common food additive, was evaluated for the inhibitory mechanisms that control citrus green mold. In vitro antifungal activity of AlS against P. digitatum was assayed on potato dextrose agar (PDA) Petri dishes with AlS concentrations of 0.38, 0.75, 1.5, 3, 6 mmol/L (mM) after 2 d and 4 d of incubation at 25 °C. The minimum inhibitory concentration (MIC) and minimum fungic ...
... Origanum vulgare L. is an aromatic plant well-known in traditional medicine and widely applied as a food additive due to its great antimicrobial potential. This study aims to investigate the chemical composition of the essential oil (EO) of O. vulgare L. using gas chromatography/mass spectroscopy (GC/MS) and evaluate their antioxidant and antibacterial activities against three strains of Salmonell ...
... Bacterial microcompartments (BMCs) are protein-based organelles that enhance a variety of metabolic functions in diverse bacteria and recent studies unveiled the importance of BMCs in bacterial adaptation from foods to gut. Comparative whole genome sequencing has shown a broad distribution of BMC-dependent metabolic pathways, but studies addressing the role of BMCs in food-related microbes are sca ...
... The present study aimed to produce a biosurfactant from Candida yeast cultivated in a low-cost medium made of sugar-cane molasses (5%), frying oil waste (5%), and corn steep liquor (5%). Initially, the production at the flask-scale was investigated and then scaled up in bioreactors to 1.2, 3.0, and 50 L to simulate a real production scale. The products obtained an excellent reduction in surface te ...
Olea europaea; antioxidants; chemical analysis; cytotoxicity; food additives; research; therapeutics
Abstract:
... The Olea europaea L. is a very well-known and widely used plant, especially for its nutritional qualities. Its extracts from leaves and fruits are widely used in contrasting and preventing various pathologies. In this review, the collected data highlight important chemical analyses and biological effects of this plant extracts. It exhibits cholesterol-lowering, hypoglycemic, cytotoxic, antibacteri ...
... Citron (Citrus. medica L.) fruits are commonly utilized in the production of essential oil, therefore, the fruits residues turn out to be industrial byproducts. In the present study, a crude polysaccharide was extracted from citron fruit residues by hot water extraction and precipitation of ethanol (95%), after deproteinization, a major polysaccharide component (CMLP-2) was obtained by gradient et ...
... This review summarizes the potential use of citrus peels in the food industry. The present work is an overview of different compounds extracted from various species of citrus peel and the functional properties of different compounds, along with their potential applications as valuable ingredients in food-based products. Citrus peel is a valuable natural source of diverse bioactive compounds, inclu ...
Coccinia grandis; apoptosis; biomarkers; caspases; chemical constituents of plants; dietary supplements; ethanol; exercise; fast foods; food additives; hepatocytes; high fat diet; hunger; inflammation; liver; monosodium glutamate; reactive oxygen species; shrinkage; society; taste; transcription factor NF-kappa B
Abstract:
... In the present socioeconomic era, people are consuming ready‐made fast‐food regularly with minimal physical exercise. Food processors use monosodium glutamate, saturated fatty acids, and hydrogenated fats to prepare flavor‐enhancing high‐lipid diet (FHD), which cause oxidative damage to different experimental animals and humans through the generation of reactive oxygen species. This study aimed to ...
food additives; food industry; food safety; laws and regulations; liquid-liquid extraction; nuclear magnetic resonance spectroscopy; polydimethylsiloxane; public health; quantitative analysis; shelf life; silicon
Abstract:
... Food additives are in widespread use in the food industry to extend the shelf life of food, improve its organoleptic characteristics or facilitate industrial processing. Their use is not without controversy, which makes regulation and control crucial for food safety and public health. Among food additives, silicone-based antifoaming agents (polysiloxanes or E900) are difficult to analyze and quant ...
European Union; Salvia officinalis; chemical compounds; essential oils; food additives; food industry; ingredients; oils; postharvest technology; raw materials; sage; temperature; weed control
Abstract:
... Salvia officinalis is commonly used as an ingredient in the food industry and has been shown to possess several biological activities. The essential oil (EO) of S. officinalis is characterized by thujones compounds, which are subjected to certain limits in the European Union (EU), as food additive. Sage inflorescences have different profile compared to leaves, with lower content in thujones, and c ...
... The current scenario of global trends impacts the way in which food is consumed and packed, meaning that change is inevitable and just around the horizon in terms of making food packaging eco-friendlier and more sustainable. Scientific advancements over the past decades have led to a wide spectrum of solutions to this problem in terms of smart, active, and antimicrobial packaging systems. The incr ...
... Alicyclobacillus acidoterrestris has been regarded as the main hazardous factor causing the spoilage of commercially pasteurized fruit juice due to its unique thermo-acidophilic properties. p-Coumaric acid, primarily isolated from plants and having high biological activity, is supposed to be a viable food additive. Herein, the antibacterial activity and mechanism of p-coumaric acid against A. acid ...
... This study aimed to investigate the synergistic bactericidal activity and mechanism of dual-stage light-guided membrane and DNA-targeted photodynamic inactivation (PDI) by the combination of blue light (BL, 420 nm) and the food additive octyl gallate (OG) against Vibrio parahaemolyticus in planktonic and biofilm growth modes. While OG serves as an outstanding exogenous photosensitizer, the plankto ...
food additives; intestinal microorganisms; intestines; research; titanium dioxide; trace elements
Abstract:
... Food-grade titanium dioxide (TiO₂) containing a nanoparticle fraction (TiO₂ NPs-nanoparticles) is widely used as a food additive (E171 in the EU). In recent years, questions concerning its effect on the gastrointestinal microbiota have been raised. In the present study, we examined interactions between bacteria and TiO₂. The study involved six pathogenic/opportunistic bacterial strains and four di ...
... TiO₂ (E171) is widely used in processed food as a coloring agent. However, growing concerns about the potential health effects of TiO₂ nanoparticles (< 100 nm) have necessitated the need for monitoring the size distribution and cytotoxic properties of food additive TiO₂ present in commercial food. In this study, we employed magnetic separation method to extract food additive TiO₂ from 100 commerci ...
... The effect of alkali on the rheological properties and microstructure of dough was investigated. Also, the color and sensory properties of alkali‐added noodles were evaluated. The results showed that the dough quality indexes and tensile properties increased with the addition of alkali. The test results of frequency sweep, stress relaxation, and creep recovery showed that the elasticity, hardness, ...
... Monosodium Glutamate is a well-known food additive with widespread usage in food industries. Contrary to that it has long been used as a cheap source of fertilizer owing to the presence of high nitrogen contents in it. Moreover, it also shows genotoxic effects on plants. However, its potential as a mutagen has never been established. Hence, the present research was extended not only to explore the ...
... Daylily is an edible flower in China. Daylily powder is prepared from the flowered or damaged by‐products during its processing, which accounts for 10% of the total amount. In order to optimize the drying methods, the powder properties, internal structure, nutrition, and color of daylily powder prepared by natural air drying (ND), hot air drying (HD), vacuum freeze‐drying (FD), and spray drying (S ...
Acinetobacter; Arthrobacter; Cynoglossus semilaevis; aquaculture; bioavailability; community structure; diet; fish; fish nutrition; food additives; growth performance; intestinal microorganisms; intestines; toxicity; weight gain
Abstract:
... Nano-selenium (Se) has attracted growing attention due to its high bioavailability, low toxicity and its possible applications in the prevention of oxidative damage in animal tissues. Recent research works have conveyed that the use of nano-seleniumas food additive could have positive effects on the nutrition of aquatic animals.In this study, the intestinal bacterial communities associated with lo ...
Lactobacillus; acidity; anthocyanins; antioxidant activity; antioxidants; astringency; bitterness; fermentation; food additives; green tea; heat treatment; leaf extracts; mulberries; nutrient content; odors; off flavors; silkworms; sourness; sweetness; traditional medicine; yogurt; Asia
Abstract:
... Mulberry leaf extract (MLE) was used to enhance the functionality of yogurt. Yogurt was fermented with 15% MLE prepared using different thermal treatment methods: no treatment (MY), steamed (SMY), and roasted (RMY). The controls were yogurt with no MLE (Y) and green tea extract (GY). Yogurt acidity was not significantly different among the samples after 8 hr of fermentation. Lactobacilli count was ...
... The aim of this study was to elucidate the physicochemical properties and sensory acceptability of pineapple drinks with different concentrations (0%–6%) of dried sour plum. The physicochemical properties (pH, total soluble solids [TSS], turbidity, color, minerals, vitamin C) were determined, and sensory evaluations were conducted. The results showed that the addition of dried sour plum contribute ...
... A series of alkyl gallates were evaluated for the antibacterial activity against two common Gram-negative foodborne bacteria (Pseudomonas fluorescens and Vibrio parahaemolyticus) associated with seafood. The length of the alkyl chain plays a pivotal role in eliciting their antibacterial activities and octyl gallate (OG) exerted an excellent inhibitory efficacy. To extend the aqueous solubility, st ...
... The goal of this study was to elucidate the mechanism by which thymol caused membrane damages in Bacillus cereus cells and the feasibility of its application in the preservation of skim milk. The minimum inhibitory concentration (MIC) of thymol was determined using the broth microdilution method. The membrane potentials, intracellular adenosine triphosphate (ATP) concentrations, and pH gradients a ...
... Saffron (Crocus sativus L.) spice, traditionally used as food additive for its coloring and flavoring properties, has shown great potential to promote health. Among the main constituents of saffron spice, safranal has been shown to alleviate and prevent gastric disorders, cardiovascular diseases and to exert anticonvulsant, anxiolytic, antidepressive and neuroprotective activities. In this work, w ...
Min-Kyeong Lee; Youn-Hwan Hwang; Heeyeon Ryu; Ami Lee; Hyeon Hak Jeong; Jiwon Baek; Myeong-Jin Kim; Ji Yun Lee; Ji Yun Van; Yunshan Liu; Chun Whan Choi; Min Soo Kim; Bonggi Lee
antioxidant activity; apple juice; ascorbic acid; catechol oxidase; food additives; food chemistry; phytochemicals; toxicity; traditional medicine
Abstract:
... Although Galla rhois has been used as a traditional medicine in Asian countries, there was no application of it in anti-browning food additives. Here, we tested whether Galla rhois inhibits apple juice browning. Apple juice browning was blocked at 250–1000 µg/ml of Galla rhois for 16 days but the effect of vitamin C did not last until a day. In vitro assays showed that the antioxidant capacity of ...
Paula Correia Medeiros dos Santos; Larissa Morais Ribeiro da Silva; Francisco Ernani Alves Magalhaes; Fernando Eugenio Teixeira Cunha; Maria Jaiana Gomes Ferreira; Evânia Altina Teixeira de Figueiredo
... Garlic (Allium sativum L.) is a spice widely used both as food and for its medicinal effects, however, much of the research on A. sativum is limited to the study of the bulb, even though the garlic peel corresponds to 25% of total production and is generally discarded by industry. In order to obtain a use of this co-product, the objective of this work was to elaborate plant extracts from the peel ...
... We assessed the genotoxicity of 30 food-flavoring chemicals used in Japan that have not been investigated before. These 30 food-flavoring chemicals have representative chemical structures belonging to 18 chemical classes. The Ames and chromosomal aberration (CA) tests (in vitro tests) were first conducted in accordance with the “Food Additive Risk Assessment Guidelines” of the Japan Food Safety Co ...
... PURPOSE: The development of a green route to obtain bioactive compounds is of great interest, contributing to the value of underused matrices such as the Soursop leaves. METHODS: Deep eutectic solvents (DES) using cholinium chloride as HBA, and alcohols and sugars as HBD, were combined with the ultrasound-assisted solid–liquid extraction (UA-SLE) to obtain bioactive compounds from soursop leaves. ...
... Since its discovery in the late eighteenth century and mass production in the early twentieth century, titanium dioxide has been used in a wide range of applications such as paints, cosmetics, energy storage, photocatalysis and food. Health concerns regarding TiO₂ use as a food additive, named E171 in Europe, are mainly due to the presence of nanoparticles, whereas it should contain only micropart ...
... PURPOSE: Anabasis articulata (Forssk.) Moq. (Chenopodiaceae), also called Eshnan, Ajremor Berry bearing glasswort, is widely distributed in Syrian, Algerian, Jordan, Lebanon, Saudi Arabia, Egyptian and Iraqi desert, Spain (Alicante, Almería, Granada and Murcia provinces), Mauritania, Western Sahara and Morocco. Anabasis articulata is broadly used in folk medicine to treat diabetes, fever, eczema a ...
... Natural products have gained considerable attention for improving fish growth performance and immunity to enhance disease resistance. This study evaluated the effect of dandelion polysaccharides (DP) on skin mucosal immune parameters, immune-related gene expression, and susceptibility to pathogen challenge in the Common carp Cyprinus carpio. Diets containing four different concentrations of DP (g ...
antioxidant activity; antioxidants; apple cider; apple juice; apple pomace; apples; breads; environmental impact; fish; food additives; food safety; lipid peroxidation; meat; oxidative stability; polyphenols; solvents; storage time; temperature; ultrasonics
Abstract:
... Consumers demand healthy and natural food products. Thus, naturally derived antioxidants are emerging as a promising alternative to the use of present ingredients. Apples and apple derivative products (e.g., apple juice, apple cider, apple sauce, and others) are widely consumed throughout the world for a variety of different reasons and supply a large quantity of polyphenolic compounds. The extrac ...
... Soluble dietary fiber (SDF), which is a component of dietary fibers exhibit many physiological functions, biological activity, and good gel forming ability. In this study, extraction of SDF from corn bran was evaluated using twin-screw extrusion and ultrasonic treatment and the combinations of the respective methods with dual enzyme hydrolysis. The monosaccharide compositions, molecular weight, ph ...
... Berberine is separated from medical plants and food raw materials, and shows excellent anti‐diabetic activity and could be used as a food additive in some countries and regions. However, its inhibitory mechanisms on α‐amylase and α‐glucosidase have hardly ever been revealed in vitro. In this study, enzymatic reaction kinetics, fluorescence quenching, circular dichroism spectroscopy, and molecular ...
... In this study, the effects of different coating materials (maltodextrin and gum arabic), ultrasonication time (10–20–30 min), and core to coating ratio (1:10, 1:20, and 1:30) on microencapsulation of cranberrybush fruit were investigated. Freeze drying was applied for 48 h to obtain the microcapsules. The dependent variables of the research were encapsulation efficiency, antioxidant activity, colo ...
... The widespread use of titanium dioxide nanomaterials (TiO₂ NMs) in food and consumer products such as toothpaste or food contact materials, suggests the relevance of human oral exposure to these nanomaterials (NMs) and raises the possibility of adverse effects in the gastrointestinal tract (GIT). We previously showed that the in vitro digestion of TiO₂ NMs may increase their toxicity in intestinal ...
... Titanium dioxide (TiO₂) is commonly used as food whitening in candies, chocolates, and cakes with high carbohydrate contents. The potential interaction between the food carbohydrate and food grade TiO₂ nanoparticle was little known. Therefore, we explored the interaction between TiO₂ nanoparticles and seven common carbohydrates, including monosaccharides, disaccharides, and polysaccharides. The re ...
... Botrytis cinerea is a necrotrophic fungus that causes severe losses of postharvest pepper fruit. Moreover, this fungus is indiscriminate, causing severe disease in a variety of plant species, thus isolation and identification of the individual strains are crucial for the development of strain specific antifungal agents. In this study, B. cinerea was isolated from naturally infected green pepper fr ...
... Scorzonera L. species are important species used in folk medicine against as hypertension, arteriosclerosis, diabetes, kidney diseases, and rheumatism. In this study, phytochemical compounds, cytotoxic (against DLD‐1 (colorectal cancer) and CCD‐18Co (human colon fibroblast cell line)), antioxidant and enzyme inhibitory (against cholinesterases, tyrosinase, urease, α‐amylase, and α‐glucosidase) act ...
... Curcumin is often used as a natural food additive because of its many drug functions and biological properties; however, its poor water solubility, chemical instability, ease of degradation, relatively high rate of metabolic degradation, and low bioavailability has limited its use in functional foods and medicines. In this study, we prepared curcumin oil body (COB) emulsions by loading curcumin in ...
acrylamides; anthocyanins; beta-carotene; cheeses; chemical species; food additives; food analysis; food chemistry; gingerbread; matrix-assisted laser desorption-ionization mass spectrometry; meat; natamycin; processed foods; spatial data
Abstract:
... Mass Spectrometry imaging (MS imaging) provides spatial information for a wide range of compound classes in different sample matrices. We used MS imaging to investigate the distribution of components in fresh and processed food, including meat, dairy and bakery products. The MS imaging workflow was optimized to cater to the specific properties and challenges of the individual samples. We successfu ...
... Capsaicin widely exists in the Capsicum genus (e.g., hot peppers) and is commonly used as a food additive or medicinal material. In this work, microbial transformation of capsaicin was performed based on the three cultivated human intestinal fungi. Fourteen metabolites were obtained, and their chemical structures were elucidated by spectroscopic data analysis, including 13 compounds with undescrib ...
... Acrylamide (AA) is a potential carcinogen formed during the process of food heating. Pectin is natural food additive widely presented in fruits and vegetables. This study aimed at investigating the influence of the addition of high methoxyl apple pectin (esterification degree: 82.6%) on AA inhibition in the asparagine (Asn)/glucose (Glc) model system. Results showed that temperature (120–180 °C), ...
bisulfites; chemical species; color; density functional theory; detection limit; electron transfer; fluorescence; food additives; food chemistry; mitochondria; pH; rapid methods; sugars; sulfites
Abstract:
... Bisulfite (HSO₃–)/Sulfite (SO₃²–) is widely used as a food additive, but excessive use often leads to serious consequences, so the detection of HSO₃–/SO₃²– is of great importance. In this paper, a novel 1,4-diethylpiperazine-modified coumarin-benzopyran derivative (probe QLP) has been synthesized and characterized. In PBS (10 mM, pH = 7.4), QLP displays good selectivity and is sensitive for HSO₃–/ ...
... Food security has become closely watched with the occurrence of a series of food safety incidents in recent years. The widespread adoption of 2,3-butanedione (BUT), as a food additive, is an unpreventable significant risk factor to food security. Based on this, mouse hepatocyte AML-12 cells and two functional proteins (bovine serum albumin and lysozyme) were utilized as targeted receptors to study ...
Etil Guzelmeric; Pırıl Ugurlu; Cansel Celik; Nisa Beril Sen; Sinem Helvacıoglu; Mohammad Charehsaz; Murat Erdogan; Mehmet Ali Ockun; Hasan Kırmızıbekmez; Ahmet Aydın; Erdem Yesilada
... Myrtus communis L. (Myrtle) plant parts have been traditionally used to treat various disorders. Herein, we aimed to compare the chemical compositions, antioxidant, anticancer, and anti/-mutagenic activities of the hydroalcoholic extracts prepared from floral buds, flowers, leaves, and fruits of Myrtle. Quercitrin, myricitrin, and myricetin 3-O-β-galactopyranoside were identified in all plant part ...
... Hyssopus cuspidatus is a famous spice and an aromatic vegetable. Few information could be available concerning its non-volatile chemical composition and bioactivities. Preliminary bioactive evaluations on the crude ethanol extract and its four fractions disclosed that the ethyl acetate fraction (EAF) exhibited antioxidant and antimicrobial bioactivities. LC-MS/MS analysis of EAF helped to identify ...
... Nucleobases, nucleosides and nucleotides can act as chemical markers and immunnostimulants. Ultra-high-performance liquid chromatography with electrospray ionization and quadrupole time of flight-mass spectrometry was used to determine bioactive compounds from different yeast species isolated from extremal marine environments, Yarrowia lipolytica, Sterygmatomyces halophilus, Kluyveromyces lactis a ...
... There is a growing demand for biopolymers for packaging, dietary fiber, and as a food additive, where nanocellulose has become an important material for such purposes. In this study, a process utilizing successive steps in the same container was used, avoiding washing and neutralization between stages, showing nanocellulose isolation using a brown alga with a yield of 14.9%. Transparent films of p ...
... In order to broaden the application field of proanthocyanidins (PCs) from Zijuan tea, it is necessary to establish an environmental and economic extraction method of PCs from Zijuan tea. Based on the single‐factor experiment, Box‐Behnken response surface methodology was used to study the effects of solid–liquid ratio, the concentration of citric acid solution, ultrasonic power, ultrasonic time, an ...
... Atopic dermatitis (AD) is a chronic relapsing inflammatory disease that is primarily characterized by pruritus. AD is a multifactorial disease related to epidermal barrier disruption, which mainly occurs during infancy and childhood. Although AD is usually associated with multiple causes, including elevated IgE levels and environmental factors, the pathogenesis and etiology of AD are not fully und ...
... The excessive inflammation, oxidative stress, and impaired angiogenesis are major factors leading to difficulties in chronic wound healing. To develop bioactive materials with intrinsic antioxidant and anti-inflammatory properties, we prepared hydrogels for the first time using paramylon secreted by Euglena gracilis which is a polysaccharide has been approved by FDA as food additive. Results showe ...
World Health Organization; biosecurity; body weight; curcumin; eosin; food additives; food chemistry; food industry; oxidation; water solubility
Abstract:
... Curcumin (CUR) is a food additive approved by World Health Organization. But the shortcomings, such as poor water solubility, easy oxidation and degradation, limit its application. In this study, the CUR-loaded poloxamer₁₈₈-based nanoparticles (CUR/PTT NPs) were fabricated to improve the stability and water solubility of CUR. Studies found the spherical CUR/PTT NPs had an average size of 98.71 ± 0 ...
... Osteoarthritis is a significant driver of disability in the elderly with increasing prevalence, and inflammation plays a vital role on its etiology. Licorice is commonly used as a traditional Chinese medicine or food additive, and its prenylated phenolic compounds were recently reported to be able to inhibit osteoarthritis with anti-inflammatory activity. In order to explore more anti-osteoarthrit ...
... Nitrite is both an environmental contaminant and a food additive. Excessive intake of nitrites not only causes blood diseases, but also has the potential risk of causing cancer. Therefore, rapid detection of nitrite in water is necessary. In this work, we propose an electrochemical sensor for the sensing of nitrite. Glassy carbon electrodes modified with noble metal nanomaterials have been widely ...
... (+)-Nootkatone is an expensive sesquiterpene substance found in grapefruit peels and the heartwood of yellow cedar. It can be used as a food additive, perfume, and insect repellent; therefore, its highly efficient production is greatly needed. However, the low catalytic efficiency of the membrane-anchored cytochrome P450/P450 reductase system (HPO/AtCPR) is the main challenge and limits the produc ...
agriculture; blood serum; calorimetry; esterases; food additives; heat production; human serum albumin; hydrogen; hydrophobicity; protein structure; skeleton; sodium; solvents; spectroscopy; titration; toxicity; tryptophan; van der Waals forces
Abstract:
... BACKGROUND: Sodium dehydroacetate (DHA‐S) is a common food additive, which can combine with serum proteins in the plasma, but the interaction mechanism between DHA‐S and human serum albumin (HSA) is unclear. In this study, multiple spectroscopy techniques, isothermal titration calorimetry (ITC), molecular docking and esterase activity test were employed to investigate the interaction mechanism of ...
Moringa oleifera; bioavailability; carotenoids; dietary supplements; food additives; glucosinolates; health promotion; ingredients; phytochemicals; trees; value added
Abstract:
... Based on the availability of many nutrients, Moringa oleifera tree leaves have been widely employed as nutrients and nutraceuticals in recent years. The leaves contain a small amount of anti-nutritional factors and are abundant in innumerable bioactive compounds. Recently, in several in vivo and in vitro investigations, moringa leaves’ bioactive components and functionality are highlighted. Moring ...
Camelina sativa; Food and Drug Administration; agronomic traits; arid lands; cooking fats and oils; cultivars; erucic acid; ethyl methanesulfonate; field experimentation; food additives; herbicide resistance; humans; introgression; loci; mutagenesis; mutants; profitability; salads; seed oils
Abstract:
... Erucic acid concentration in oil of most camelina (Camelina sativa L. Crantz) genotypes exceeds the 2% threshold allowed by the U.S. Food and Drug Administration (FDA) for use as a food additive. Lowering erucic acid concentration below the FDA threshold enables marketing camelina as edible oil for human consumption, greatly expanding potential uses to include food ingredients such as marinades, s ...
... Pro-senescence therapy is a recently proposed anti-cancer strategy and has been shown to effectively inhibit cancer. Resveratrol is gaining attention for its cancer preventive and suppressive properties. The mechanisms of resveratrol in cancer suppression by inducing cancer cell senescence are unclear. Our results showed that resveratrol induced cell senescence along with an increase of SA-β-Gal a ...
... Although monosodium glutamate (MSG) is a widely used food additive, its safety and systemic side effects have not been fully clarified. The intestinal flora is closely associated with human health; however, it remains unclear whether MSG consumption can affect health by acting on the intestinal flora. In this study, serum biomarkers, intestinal structure, intestinal immunity, and intestinal flora ...
... Vinegar is a common food additive produced by acetic acid bacteria (AAB) during fermentation process. Low yield and long incubation time in conventional vinegar fermentation processes has inspired research in developing efficient fermentation techniques by the activation of AAB for acetic acid production. The present study intends to enhance vinegar production using acetic acid bacteria and light ...
... Titanium dioxide (TiO₂), as a representative of metallic oxides, is widely used as food additive to serve as coloring or antibacterial packaging fortifier. However, in recent years, the potential hazards of nano-sized TiO₂ food additives to human beings is still in doubt. In this work, we systematically studied the interactions between three sizes of TiO₂ particles and the cell membrane systems wi ...
... Antibiotic tolerance has been a growing crisis that is seriously threatening global public health. However, little is known about the exogenous factors capable of triggering the development of antibiotic tolerance, particularly in vivo. Here we uncovered that an previously approved food additive termed sodium dehydroacetate (DHA-S) supplementation remarkably impaired the activity of bactericidal a ...
... Sodium dithionite (Na₂S₂O₄) is an inorganic sodium salt, a bleaching agent that has a reducing agent role and is generally used as food additive or preservative in the production of diverse foods and beverages. The aim of this study is to determine the effects of Na₂S₂O₄ on cardiac mitochondria damage and biochemical parameters in male mice. Na₂S₂O₄ were administered orally at doses of 10, 20, 50 ...
... Canned products are important part of human diet and therefore, many types of canned products with high amounts are produced worldwide. During canned production, cooking water of pulses (aquafaba) is an important waste. Therefore, recycling of it is important for sustainability and economic value. In the present study, it was aimed to determine technological properties of aquafabas obtained from c ...
... A high-salt (HS) diet leads to metabolic disorders in Dahl salt-sensitive (SS) rats, and promotes the development of hypertension. According to the changes in the metabolites of SS rats, a set of combined dietary supplements containing amino acids and organic acids (AO) were designed. The purpose of the present study was to evaluate the effect of AO supplementation on the blood pressure of SS rats ...
antioxidants; carbon nanofibers; cooking fats and oils; detection limit; eating habits; electrodes; electron transfer; food additives; food chemistry; food quality; nanocomposites; propyl gallate; rancidity; sensors (equipment); social welfare; strontium; taste
Abstract:
... The contemporary dietary pattern is ruined by taste enhancers, flavoring agents, and preservatives. Propyl gallate (PG) is an imperative phenolic antioxidant cast-off to inhibit the oxidative mutilation in foodstuffs thereby preventing rancidity. Determination and annihilation of PG are extensively concerned because of its probable lethal effects on human well-being. Herein, we report an electroch ...
... Rhododendron arboreum Smith flowers constitute a valuable dietary supplement or food additive and are novel therapeutic agents. The present work demonstrates and optimizes an effective, enzyme-based ultrasonic approach for polyphenols extraction as a potential alternative to conventional extraction methods. Enzyme-based extraction constitutes an efficient, benign, sustainable, and eco-friendly ext ...
Norha Constanza Bolívar-Ramírez; Anderson Stoffels Mallmann; Delano Dias Schleder; Claudia Machado; Walter Quadros Seiffert; Felipe do Nascimento Vieira
... This study reported on the addition of tannins to the diet of Litopenaeus vannamei and evaluated the effect on performance, immune response, intestinal microbiota, and experimental challenge against Vibrio parahaemolyticus. Tannin was added to feed in three concentrations of 0.1% (1.0 kg of tannin per ton of feed), 0.05% (500 g of tannin per ton of feed), 0.025% (250 g of tannin per ton of feed) a ...
Danio rerio; Polyrhachis; artificial colors; azorubine; body weight; dose response; ecotoxicology; food additives; genes; instars; lethal dose 50; survival rate; water solubility; weight gain
Abstract:
... Carmoisine belongs to a water-soluble synthetic dye and is often used as a food additive. Previous research has shown that carmoisine is toxic to rats and zebrafish, but there have been few reports on the effect of carmoisine on soil-dwelling social insects. The present study evaluated carmoisine toxicity in Polyrhachis vicina Roger. We found that the effects of different concentrations of carmois ...
K.A. Woodling; P. Chitranshi; C.C. Jacob; L. Loukotková; L.S. Von Tungeln; G.R. Olson; R.E. Patton; S. Francke; S.R. Mog; R.P. Felton; F.A. Beland; Y. Zang; G. Gamboa da Costa
... Brominated vegetable oil (BVO) has been approved by the US Food and Drug Administration on an interim basis as a food additive. Past studies have raised concerns about potential toxicities from consuming BVO. To investigate further these toxicities, we conducted a 90-day dietary exposure study in Sprague Dawley rats and analyzed tissue distribution of the main metabolites. Six-week-old male and fe ...
... Ceramide is a natural functional ingredient as food additive and medicine that has attracted extensive attention in the food, medical, and cosmetic industries. Here, we developed a biotechnological strategy based on a recombinant whole-cell biocatalyst for efficiently producing ceramide from crude soybean oil sediment (CSOS) waste. A novel phospholipase C (PLCₐc) from Acinetobacter calcoaceticus i ...
... PURPOSE: Maltodextrin (MDX) is a polysaccharide food additive commonly used as oral placebo/control to investigate treatments/interventions in humans. The aims of this study were to appraise the MDX effects on human physiology/gut microbiota, and to assess the validity of MDX as a placebo-control. METHODS: We performed a systematic review of randomized-placebo-controlled clinical trials (RCTs) whe ...
... Self-heal (Prunella vulgaris L.) is a perennial edible plant that is widely distributed across the world and is traditionally consumed as a food additive in soft drink beverages. In this study, to explore the functional components of P. vulgaris, an investigation of its ethanol extracts has been conducted by our group. As a result, twelve (1–12) vulgarisin-type diterpenoids with a special 5/6/4/5- ...
... Since its inception, food additive has been an integral part of the food processing industry with various commercial roles. Besides its advantages, various studies have already highlighted its long-term adverse effects on human health. However, in terms of protein structures and functions, the innate mechanism that triggers these effects has not been elucidated in previously reported studies. Our ...
... Mushrooms and truffles are attracting attention as a new generation of biotherapeutics. In the current study, isolation, phenolic and organic acid composition, and antioxidant, cytotoxic, anticholinesterase activities of truffle Reddellomyces parvulosporus were examined. Four known compounds (brassicasterol (1), ergosterol peroxide (2), fumaric acid (3) and mannitol (4)) were isolated with the com ...
amyloid; circular dichroism spectroscopy; dyes; fluorescence; food additives; human serum albumin; neurotoxicity; polyacrylamide gel electrophoresis; transmission electron microscopy
Abstract:
... Intensive research in the field of protein aggregation confirmed that the deposition of amyloid fibrils of proteins are the major cause for the development of various neurotoxic and neurodegenerative diseases, which could be controlled by ensuring the efficient inhibition of aggregation using anti aggregation strategies. Herein, we elaborated the anti amyloidogenic potential of Sunset Yellow (SY) ...
... Nanotechnology governance, particularly in relation to human and environmental concerns, remains a contested domain. In recent years, the creation of both a risk governance framework and council has been actively pursued. Part of the function of a governance framework is the communication to external stakeholders. Existing descriptions on the public perceptions of nanotechnology are generally posi ...
... Multi-drug resistant bacteria have been paying increasing attentions. Quorum sensing (QS) and QS-associated biofilms are showing the vital reasons for antibiotics resistant. In this study, 2-tert-butyl-1,4-benzoquinone (TBQ), the oxidant of tert-butyl hydroquinone (TBHQ), can potentially be the QS inhibitor (QSI) of Chromobacterium violaceum ATCC12472. After treated with 50 μg/mL of TBQ, the viola ...
Drosophila suzukii; attractants; cages; field experimentation; food additives; fruits; mineral oil; octenol; oviposition; oviposition deterrents; pests; polyethylene; raspberries; Europe; North America
Abstract:
... BACKGROUND: Drosophila suzukii (Matsumura), spotted‐wing drosophila (SWD), is a major invasive pest of soft‐skinned fruits in North America and Europe. Although insecticides are currently the primary method of SWD control, it is imperative to develop alternative management approaches, such as behavioral control through the use of repellents and attractants. This study explores the repellent proper ...
... High amounts of grains in equine diet lead to an excessive starch intake modifying microbial populations and fermentative products. These changes could compromise the gastrointestinal barrier which has serious consequences for equine health. Therefore, feed additives are receiving great attention to minimize negative effects related to high starch level inclusion. Macleaya cordata compounds are be ...
... Propylene glycol (PG; 1,2-propanediol) has been commonly used as a food additive and vehicle in pharmaceutical preparations. PG can form rectus (R-) enantiomers and sinister (S-) enantiomers. Herein, Kunming mice were used as the animal model to evaluate the acute and subacute oral toxicity of R-PG, S-PG and RS-PG (1:1 racemic mixture of R-PG and S-PG). The median lethal doses of R-PG, S-PG and RS ...
... Diallyl sulfide (DAS) is a garlic-derived organosulfur compound known for its chemotherapeutic properties, as a strong food additive and a potential radiomitigator. Despite its therapeutic potentials, the apparent lack of toxicity data hinders its clinical applications. The present study investigated the pre-clinical toxicity of DAS to identify the maximum tolerable and lethal doses and understand ...
... TiO₂ nanoparticles known as E171 are one controversial food additive due to its potential toxicity. In this work, the main hypothesis is that the proteins adsorbed on the TiO₂ nanoparticles prevent their aggregation and favor the cell penetration. To do so, the TiO₂ nanoparticles were coated with gelatin and β-lactoglobulin to reach interfacial concentrations about 0.25 mg/mg and 0.32 mg/mg, respe ...
... E150d is a food additive used to increase palatability and impart colour to foods and drinks. Known as ‘caramel dye’, it contains 4-methylimidazole, a cytotoxic molecule for animal models and human. Recently, the growing consumption of E150d causes an increasing release of this additive into the environment, particularly in water bodies. For this reason, in this study it was assessed the toxic eff ...
Agaricus bisporus; air temperature; atomization; emulsions; food additives; industry; mushrooms; particle size; porosity; solubility; water content
Abstract:
... Agglomeration process improves instant properties of powders and increases consumer appreciation, reduces losses during production, and facilitates the processability of these powders in the industry. Mushroom powders (MP) have been subjected to agglomeration process at different process parameters: inlet air temperature (50–80°C), atomizing pressure (0.5–1.5 bars), and sprayed pure water amount ( ...
batters; breads; food additives; hydrolysates; molecular weight; polyacrylamide gel electrophoresis; protein hydrolysates; rice; rice protein; rice starch; temperature; thermolysin
Abstract:
... Protease has been shown to be an effective food additive for improving the quality of gluten-free rice bread. We found that rice protein hydrolysate by bacillolysin (Protin SD-NY10) and thermolysin (Thermoase) increased the specific volume of gluten-free rice starch bread. Many fine bubble cells were observed in the crumb of the rice starch bread containing rice protein hydrolysate by proteases us ...
... In this study, the toxic effects of monosodium glutamate (MSG), which is the sodium salt of glutamic acid and used as a flavor-enhancing additive in foods, and the protective role of cape gooseberry (Physalis peruviana L.) extract against these effects were investigated using Allium cepa L. test material with physiological, cytogenetic, and biochemical parameters. In the study, physiological chang ...
... Fisetin (Fis), quercetin (Que), and myricetin (Myr) are flavonols with similar structure but different number of hydroxyl groups. The present research focused on the anti-inflammatory effect of these three flavonols in lipopolysaccharide-stimulated RAW264.7 cells. The number and site of hydroxyl group in flavonols obviously affected their anti-inflammation activity. These flavonols suppressed the ...
... Sucrose laurate (SL) is a promising dual-functional additive due to its emulsification and antibacterial activity. However, the knowledge on the antibacterial action of SL against Bacillus cereus was lacking, and thus it was investigated from multiple targets. The antibacterial results demonstrated that the minimum inhibitory concentration of SL was 0.3125 mg/mL, and the time-killing curve confirm ...
... Automatic solvent extraction (ASE) was employed to acquire orange peel extract rich in carotenoid by means of several solvents (hexane, heptane, and chloroform). D‐optimal design was used for the design of experiments, modeling the experimental data, and optimization of the extraction process. Selected process parameters (extraction time, particle size of the peel, and solvent type) for the curren ...
... The essential oil of Litsea cubeba (Lour.) Pers. (LCEO) has applications as a health and food additive. The study objectives were to demonstrate the toxicity of LCEO against Drosophila and to investigate the essential oil’s mechanism of action. The repellency percentage, fumigation effect and contact activity were all positively correlated with the LCEO concentration, and 1.0 μL/cm² essential oil ...
... Shelf life extension can reduce food losses throughout the entire food chain and packaging can be an effective way to attain this goal. Along these lines, active packaging is an appealing alternative that uses natural antimicrobial compounds to inhibit the growth of microorganisms causing food spoilage. Specifically, a packaging was developed based on polyethylene film with a coating fully compati ...
Caesalpinia sappan; Sequoia sempervirens; digestive tract; diterpenoids; dyes; food additives; heart; herbal medicines; intestines; kidneys; liver; neuroprotective effect; pharmacodynamics; pharmacokinetics; phenolic compounds; phytochemicals; toxicology; South East Asia
Abstract:
... Caesalpinia sappan Linn. or Sappanwood is a redwood, full-fledged in numerous parts of Southeast Asia and well known for its red pigments, dye, food additive, and several medicinal properties. Many active chemical compounds in sappanwood extract have been identified and evaluated for medicinal properties such as anticancer, antimicrobial, anti-inflammatory, anti-arthritic, neuroprotective effect, ...
... Food additives and colorants are extensively used in the food industry to improve food quality and safety during processing, storage and packing. Sourcing of these molecules is predominately through three means: extraction from natural sources, chemical synthesis, and bio-production, with the first two being the most utilized. However, growing demands for sustainability, safety and “natural” produ ...
... In 2011, we published a paper providing an overview about the bioavailability, efficacy, and regulatory status of creatine monohydrate (CrM), as well as other “novel forms” of creatine that were being marketed at the time. This paper concluded that no other purported form of creatine had been shown to be a more effective source of creatine than CrM, and that CrM was recognized by international reg ...