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- Alvarez-Martinez, Cristina, et al. Show all 6 Authors
- Journal of bacteriology 2012 v.194 no.15 pp. 4041-4051
- Enterococcus faecalis; adenosine triphosphate; adenosinetriphosphatase; binding sites; genes; hydrolysis; models; mutants; mutation; nucleoside-triphosphate phosphatase; plasmids; proteins; secretion
- ... The Enterococcus faecalis prg and pcf genes of plasmid pCF10 encode a type IV secretion system (T4SS) required for conjugative transfer. PrgJ is a member of the VirB4 family of ATPases that are universally associated with T4SSs. Here, we report that purified PrgJ dimers displayed ATP binding and hydrolysis activities. A PrgJ nucleoside triphosphate (NTP) binding site mutation (K471E) slightly dimi ...
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