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- Chen, Jiaqi, et al. Show all 8 Authors
- Developmental and comparative immunology 2015 v.52 no.1 pp. 58-68
- Primates; RNA viruses; Tupaia; amino acid sequences; amino acids; animal models; caspases; complementary DNA; gene expression; genes; humans; innate immunity; interferon-beta; messenger RNA; mitochondria; mutants; phylogeny; polypeptides; quantitative polymerase chain reaction; signal transduction; transcription factor NF-kappa B
- ... Human mitochondrial antiviral signaling protein (hMAVS, also known as IPS-1, VISA, or Cardif) is essential for antiviral innate immunity. The Chinese tree shrew (Tupaia belangeri chinenses), a close relative of primates, is emerging as a potential animal model for investigating viral infection. However, there is a lack of biological knowledge about the antiviral innate immunity of the tree shrew. ...