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- Fu, Songbin, et al. Show all 4 Authors
- Molecular biology reports 2010 v.37 no.6 pp. 2829-2838
- Western blotting; adenocarcinoma; agar; cDNA libraries; cell proliferation; complementary DNA; genes; humans; interphase; lung neoplasms; messenger RNA; metastasis; mice; nucleotide sequences; phenotype; reverse transcriptase polymerase chain reaction; screening
- ... Understanding the genesis and development of tumors is an essential component in cancer research. It is of interest to discover unknown genes that are responsible for cellular transformation. A cDNA library of a highly metastatic lung adenocarcinoma cell line was constructed. This library was introduced into the NIH3T3 mouse embryonic fibroblast cell line to screen for cDNAs that increase anchorag ...
- Fu, Songbin, et al. Show all 9 Authors
- Nucleic acids research 2011 v.39 no.suppl_1 pp. D895
- human diseases; DNA damage; humans; crossing over; DNA; chromosome aberrations; genes; nucleotide sequences; databases
- ... Chromosomal rearrangement (CR) events result from abnormal breaking and rejoining of the DNA molecules, or from crossing-over between repetitive DNA sequences, and they are involved in many tumor and non-tumor diseases. Investigations of disease-associated CR events can not only lead to important discoveries about DNA breakage and repair mechanisms, but also offer important clues about the patholo ...