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- Author:
- Gong, Yajie, et al. ; Chen, Xueqin; Wang, Ying; Chen, Xiaohua; Cheng, Kailiang; Li, Jiaoyuan; Lou, Jiao; Ke, Juntao; Yang, Yang; Zhu, Ying; Wang, Li; Zhong, Rong; Show all 12 Authors
- Source:
- Infection, genetics, and evolution 2016 v.44 pp. 495-500
- ISSN:
- 1567-1348
- Subject:
- Chinese people; Hepatitis B virus; alcohol drinking; genetic variation; genotype; genotyping; hepatitis B; humans; linear models; liver; luciferase; regression analysis; reverse transcriptase polymerase chain reaction; risk; single nucleotide polymorphism; sodium; symporters; transcription (genetics)
- Abstract:
- ... The Na/taurocholate cotransporter NTCP (encoded by SLC10A1) was identified as a cellular entry receptor for the human hepatitis B virus (HBV), advancing our understanding of the molecular mechanism of HBV infection. An alternative hypothesis was put forward that regulatory variants in SLC10A1 might play an important role in HBV susceptibility by potentially influencing expression levels of NTCP. T ...
- DOI:
- 10.1016/j.meegid.2016.07.043
-
https://dx.doi.org/10.1016/j.meegid.2016.07.043