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1. 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy

Author:
Jeeyoun Jung; Woo Yeong Park; Yun Jin Kim; Mikyung Kim; Misun Choe; Kyubok Jin; Ji Hae Seo; Eunyoung Ha
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
3-hydroxybutyric acid; albumins; autophagy; blood glucose; blood serum; cages; creatinine; diabetic nephropathy; energy expenditure; glucose; histology; hyperglycemia; kidneys; noninsulin-dependent diabetes mellitus; obesity; oxidative stress; phenotype; phosphorylation; quantitative analysis; reactive oxygen species; urea nitrogen; urine
Abstract:
... Studies report beneficial effects of 3-hydroxybutyrate (3-OHB) on the treatment of type 2 diabetes and obesity, but the effects of 3-OHB on diabetic nephropathy have not been elucidated. This study was designed to investigate the efficacy and mechanism of 3-OHB against progression of diabetic nephropathy (DN). Mice (db/db) were fed normal chow, high-fat, or ketogenic diets (KD) containing precurso ...
DOI:
10.3390/antiox11020381

2. A New Fungal Triterpene from the Fungus Aspergillus flavus Stimulates Glucose Uptake without Fat Accumulation

Author:
Dan-dan Li; Ying Wang; Eun La Kim; Jongki Hong; Jee H. Jung
Source:
Marine drugs 2022 v.20 no.3 pp. -
ISSN:
1660-3397
Subject:
Aspergillus flavus; adipogenesis; agonists; biological assessment; fractionation; fungi; glucose; glycemic effect; humans; hypoglycemic agents; lipids; liver; obesity; rats; transcriptional activation; triterpenoids; weight gain
Abstract:
... Through activity-guided fractionation, a new triterpene (asperflagin, 1) was isolated as a PPAR-γ agonist from the jellyfish-derived fungus Aspergillus flavus. Asperflagin displayed selective and moderate transactivation effects on PPAR-γ in Ac2F rat liver cells. Based on further biological evaluation and molecular docking analysis, we postulated that asperflagin might function as a PPAR-γ partial ...
DOI:
10.3390/md20030203

3. A Novel MIR503HG/miR-497-5p/CCL19 Axis Regulates High Glucose-Induced Cell Apoptosis, Inflammation, and Fibrosis in Human HK-2 Cells

Author:
Danping Zhang; Xiaoxiao Chen; Dan Zheng
Source:
Applied biochemistry and biotechnology 2022 v.194 no.5 pp. 2061-2076
ISSN:
0273-2289
Subject:
Western blotting; apoptosis; biotechnology; cell viability; cytotoxicity; diabetic nephropathy; fibrosis; flow cytometry; genes; glucose; humans; inflammation; ligands; microRNA; precipitin tests; quantitative polymerase chain reaction
Abstract:
... Long non-coding RNAs (lncRNAs) play crucial roles in the development of diabetic nephropathy (DN). Here, we explored the activity and mechanism of MIR503 host gene (MIR503HG) in high glucose (HG)-evoked cytotoxicity in HK-2 cells. MIR503HG, microRNA (miR)-497-5p, and C–C motif chemokine ligand 19 (CCL19) were quantified by quantitative real-time PCR (qRT-PCR) and western blot. The direct relations ...
DOI:
10.1007/s12010-021-03776-6

4. A Sub-6 nm MnFe2O4-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy

Author:
Zan Dai; Qiaoyun Wang; Jie Tang; Rui Qu; Min Wu; Haoze Li; Yannan Yang; Xu Zhen; Chengzhong Yu
Source:
Biomaterials 2022 v.284 pp. 121533
ISSN:
0142-9612
Subject:
T-lymphocytes; adenosine; biocompatible materials; catabolism; cytotoxicity; dichloroacetic acid; glucose; immunostimulants; immunosuppression; immunotherapy; lactic acid; mitochondria; nanocomposites; neoplasms; oxygen
Abstract:
... Adenosine and lactate accumulated in tumor microenvironment are two major causes of immunosuppression, their concurrent downregulation holds promise in effective cancer immunotherapy, but remains challenging. Here, a sub-6 nm MnFe₂O₄ conjugated with dichloroacetic acid (DCA) nanoparticle is developed to modulate tumor glucose metabolism and ATP catabolism for reversing the tumor immunosuppressive ...
DOI:
10.1016/j.biomaterials.2022.121533

5. A branched galactoglucan with flexible chains from the basidioma of Macrolepiota albuminosa (Berk.) Pegler

Author:
Yu-Xiao Wang; Yue Xin; Xiao-Jun Huang; Jun-Yi Yin; Shao-Ping Nie
Source:
Food chemistry 2022 v.367 pp. 130738
ISSN:
0308-8146
Subject:
Macrolepiota; X-ray diffraction; aqueous solutions; basidiomata; ethanol; food chemistry; glucose; molecular weight; polysaccharides; steady flow
Abstract:
... A homogeneous galactoglucan was purified from the alkali-extracted polysaccharides from the basidioma of Macrolepiota albuminosa by gradient ethanol precipitation, whose proposed structure was given for the first time. Results showed it had a molecular weight of 210 kDa, and mainly consisted of glucose and galactose. There were abundant filaments, randomly distributed sheet-like and flaky appearan ...
DOI:
10.1016/j.foodchem.2021.130738

6. A comparative study on the structural and functional properties of water‐soluble and alkali‐soluble dietary fibres from rice bran after hot‐water, ultrasound, hydrolysis by cellulase, and combined pre‐treatments

Author:
Daiva Zadeike; Ruta Vaitkeviciene; Rimgaile Degutyte; Joana Bendoraitiene; Zaneta Rukuiziene; Darius Cernauskas; Mantas Svazas; Grazina Juodeikiene
Source:
International journal of food science & technology 2022 v.57 no.2 pp. 1137-1149
ISSN:
0950-5423
Subject:
adsorption; bioactive properties; chemical structure; comparative study; dietary fiber; endo-1,4-beta-glucanase; food science; glucose; hydrolysis; polysaccharides; rice bran; ultrasonic treatment; ultrasonics; water solubility
Abstract:
... The aim of the study was to estimate the optimum method to obtain water‐soluble (WS‐DF) and alkali‐soluble (AS‐DF) dietary fibres fibres from defatted rice bran (DRB) to develop functional components for food. The different pre‐treatments of DRB, such as ultrasound (US) treatment, hydrolysis by cellulase (HC) and combined treatment (HC‐US), were compared with hot‐water (HWT) treatment on yields, a ...
DOI:
10.1111/ijfs.15480

7. A comparison between high carbohydrate and high lipid diets reception on the growth, feed utilization and glucose homeostasis of genetically improved farmed tilapia Oreochromis niloticus

Author:
Kang-Wei Wang; Jun-Xing Chen; Qin-Qin Liu; Xin Deng; Li Luo; Shi-Mei Lin; Yong-Jun Chen
Source:
Aquaculture reports 2022 v.24 pp. 101119
ISSN:
2352-5134
Subject:
Oreochromis niloticus; acetyl-CoA carboxylase; aquaculture; blood glucose; body weight; carboxy-lyases; dietary carbohydrate; energy density; fatty-acid synthase; feed conversion; gene expression; gluconeogenesis; glucose; glucose transporters; glucose-6-phosphatase; glycogen; glycogen (starch) synthase; glycogenesis; glycogenolysis; glycolysis; growth performance; high carbohydrate diet; high fat diet; homeostasis; hyperglycemia; lipids; lipogenesis; liver; protein efficiency ratio; protein subunits; proximate composition; satiety; starch
Abstract:
... This study was performed to compare the effects of high carbohydrate and high lipid diets reception on the growth, feed utilization and glucose homeostasis of genetically improved farmed tilapia Oreochromis niloticus. Three isonitrogenous (ca 30.2% protein) diets were formulated with different levels of starch and lipid: the control (CON, 24.2% starch and 6.57% lipid), high carbohydrate diet (HCD, ...
DOI:
10.1016/j.aqrep.2022.101119

8. A cyclic process for enzymatic hydrolysis and fermentation of lactic acid pretreated reed

Author:
Minghao Chen; Hao Tong; Huan Liu; Jie Lu; Jian Du; Yehan Tao; Yi Cheng; Haisong Wang
Source:
Industrial crops and products 2022 v.181 pp. 114848
ISSN:
0926-6690
Subject:
digestibility; enzymatic hydrolysis; fermentation; glucans; glucose; lignin; liquids; polylactic acid; temperature
Abstract:
... This research aims to explore a green, economical and recyclable pretreatment method to enhance the enzymatic digestibility of reed. In this study, lactic acid (LA) as a kind of weak organic acid was used to pretreat reed. The results of orthogonal experiments showed that temperature was the most dominant influencing factor for the pretreatment process. Linear experiments conducted the optimum tem ...
DOI:
10.1016/j.indcrop.2022.114848

9. A detailed review on the phytochemical profiles and anti-diabetic mechanisms of Momordicacharantia

Author:
Sunday Faith Oyelere; Oluwatobi Hezekiah Ajayi; Titilayo Eunice Ayoade; George Bueno Santana Pereira; Bolaji Charles Dayo Owoyemi; Ajibola Olaoluwa Ilesanmi; Olalekan Amos Akinyemi
Source:
Heliyon 2022 v.8 no.4 pp. e09253
ISSN:
2405-8440
Subject:
absorption; catabolism; diabetes mellitus; glucose; glucose-6-phosphatase; insulin; insulin resistance; mortality; phytochemicals
Abstract:
... Diabetes mellitus is the most well-known endocrine dilemma suffered by hundreds of million people globally, with an annual mortality of more than one million people. This high mortality rate highlights the need for in-depth study of anti-diabetic agents. This review explores the phytochemical contents and anti-diabetic mechanisms of M. charantia (cucurbitaceae). Studies show that M. charantia cont ...
DOI:
10.1016/j.heliyon.2022.e09253

10. A handheld 3D-printed microchip for simple integration of the H2O2-producing enzymatic reactions with subsequent chemiluminescence detection: Application for sugars

Author:
Haider A.J. Al Lawati; Javad Hassanzadeh; Nafiseh Bagheri
Source:
Food chemistry 2022 v.383 pp. 132469
ISSN:
0308-8146
Subject:
chemiluminescence; enzymatic reactions; enzymes; food chemistry; fructose; glucose; honey; juices; lab-on-a-chip technology; maltose; rice flour; storage quality; sucrose; zinc
Abstract:
... Herein, a novel lab-on-a-chip (LoC) device fabricated by 3D printing based on H₂O₂-producing enzymatic reactions with sensitive chemiluminescence (CL) detection was developed to measure different sugars, including glucose, fructose, sucrose, and maltose, in honey, juice, and rice flour samples. The pumpless microchip included two main parts, separated by new cone-shape blocking valves; part A for ...
DOI:
10.1016/j.foodchem.2022.132469

11. A high extra-virgin olive oil diet induces changes in metabolic pathways of experimental mammary tumors

Author:
Maite Garcia-Guasch; Lourdes Navarro; Vanessa Rivero; Irmgard Costa; Eduard Escrich; Raquel Moral
Source:
Journal of nutritional biochemistry 2022 v.99 pp. 108833
ISSN:
0955-2863
Subject:
anthracenes; apoptosis; breast neoplasms; corn; corn oil; etiology; extra-virgin olive oil; glucose; lipid metabolism; mammary glands; mitochondria; models; neoplasm progression; nutritional intervention; rats
Abstract:
... Breast cancer is the most common malignancy in women worldwide, and environmental factors, especially diet, have a role in the etiology of this disease. This work aimed to investigate the influence of high fat diets (rich in corn oil or extra virgin olive oil -EVOO-) and the timing of dietary intervention (from weaning or after induction) on tumor metabolism in a seven,12-dimethylbenz[a]anthracene ...
DOI:
10.1016/j.jnutbio.2021.108833

12. A high molecular weight polymalate is synthesized by the whole genome duplicated strain Aureobasidium melanogenum OUC

Author:
Cong-Yan Qi; Zhe Chi; Guang-Lei Liu; Zhen-Ming Chi
Source:
International journal of biological macromolecules 2022 v.202 pp. 608-619
ISSN:
0141-8130
Subject:
Aureobasidium; biosynthesis; fermentation; genes; glucose; hydrogels; molecular weight; noodles
Abstract:
... Polymalate (PMA) produced by the whole genome duplicated strain Aureobasidium melanogenum OUC had a high molecular weight (Mw) of 3.9 × 10⁵ Da while the Mw of PMA produced by A. melanogenum ATCC62921 was 3.8 × 10⁴ Da. Therefore, the purified PMA produced by A. melanogenum OUC could form hydrogel and film and the precipitated Ca²⁺-PMA looked like noodle whereas the purified PMA produced by A. melan ...
DOI:
10.1016/j.ijbiomac.2022.01.125

13. A metabolomics comparison in milk from two Dezhou donkey strains

Author:
Yan Li; Qing-shan Ma; Miao-miao Zhou; Zhen-wei Zhang; Yan-dong Zhan; Gui-qin Liu; Ming-xia Zhu; Chang-fa Wang
Source:
European food research & technology 2022 v.248 no.5 pp. 1267-1275
ISSN:
1438-2377
Subject:
alanine; arginine; aspartic acid; ass milk; asses; biosynthesis; breast milk; choline; comparative study; food research; glucose; glutamic acid; glutamine; lactation; metabolites; metabolomics; milk; milk composition; milk quality; starch; sucrose; technology
Abstract:
... Due to its similarity with human milk, donkey milk is gaining interest as a nutritional milk source. The aim of current study was to compare the difference in the milk composition and metabolites of two Dezhou donkey strains (SanFen and WuTou). The results showed that fat, total solids, and solids-not fat of SanFen milk were higher than WuTou milk. Then we further identified the metabolites in the ...
DOI:
10.1007/s00217-022-03962-8

14. A microfluidic cloth-based photoelectrochemical analytical device for the detection of glucose in saliva

Author:
Xinyuan Mao; Chunsun Zhang
Source:
Talanta 2022 v.238 pp. 123052
ISSN:
0039-9140
Subject:
ammonium; cadmium sulfide; carbon; carbon nanotubes; detection limit; electric current; electrodes; glucose; saliva
Abstract:
... Photoelectrochemical (PEC) detection is a widely used detection method that uses light to stimulate and photocurrent signals to detect the target. Due to the disengagement of the excitation unit and the detection unit, the PEC background signal is reduced, and the detection sensitivity is improved. In this work, we report the first demonstration of PEC detection for microfluidic cloth-based analyt ...
DOI:
10.1016/j.talanta.2021.123052

15. A network pharmacology-based strategy to explore the pharmacological mechanisms of Antrodia camphorata and antcin K for treating type II diabetes mellitus

Author:
Yi Kuang; Yue Chai; Huifei Su; Jen-Yu Lo; Xue Qiao; Min Ye
Source:
Phytomedicine 2022 v.96 pp. 153851
ISSN:
0944-7113
Subject:
Taiwanofungus camphoratus; adiponectin; blood serum; carbohydrate metabolism; fungi; glucose; glucose tolerance tests; high fat diet; insulin; insulin resistance; interleukin-6; leptin; mortality; pharmacology; quality of life
Abstract:
... Diabetes mellitus is a chronic carbohydrate metabolism disorder, which could develop a series of complications and thus lead to poor quality of life or even mortality. Antrodia camphorata is a rare parasitic fungus and has been proven to be effective for treating type II diabetes.This study aims to evaluate the anti-diabetic activities of A. camphorata and its main compound antcin K, as well as to ...
DOI:
10.1016/j.phymed.2021.153851

16. A novel NiVP/Pi-based flexible sensor for direct electrochemical ultrasensitive detection of cholesterol

Author:
Neha Thakur; Debaprasad Mandal; Tharamani C. Nagaiah
Source:
Chemical communications 2022 v.58 no.16 pp. 2706-2709
ISSN:
1364-548X
Subject:
ascorbic acid; blood serum; cholesterol; coronary disease; detection limit; electrochemistry; glucose; humans; pH; sensors (equipment); uric acid
Abstract:
... A novel non-enzymatic electrochemical sensor was constructed to achieve a highly selective and ultrasensitive detection of cholesterol to address the problems related to serious coronary heart disease. The NiVP/Pi-based sensor exhibited ultra-high sensitivity of 5510.18 μA μM⁻¹ cm⁻² and 36.8 μA μM⁻¹ cm⁻² for 1 nM to 10 μM and 100 μM to 10 mM of cholesterol, respectively, with an ultra-low detectio ...
DOI:
10.1039/d1cc07115g

17. A novel glucofucobiose with potential prebiotic activity prepared from the exopolysaccharides of Clavibacter michiganensis M1

Author:
Mengshi Xiao; Xinmiao Ren; Jinzheng Cui; Rong Li; Zhemin Liu; Lin Zhu; Qing Kong; Xiaodan Fu; Haijin Mou
Source:
Food chemistry 2022 v.377 pp. 132001
ISSN:
0308-8146
Subject:
Clavibacter michiganensis; acidolysis; anticoagulants; breast milk; exopolysaccharides; fermentation; food chemistry; fucose; glucose; molecular weight; oligosaccharides; prebiotics; probiotics; short chain fatty acids
Abstract:
... Fucose and fucosylated oligosaccharides have important applications in various industries owing to their prebiotic, anti-inflammatory, anticoagulant, and antiviral activities. Here, we aimed to obtain fucosylated oligosaccharides using the acidolysis method to depolymerize exopolysaccharides extracted from Clavibacter michiganensis M1. Based on structural analysis, the prepared glucofucobiose was ...
DOI:
10.1016/j.foodchem.2021.132001

18. A novel polysaccharides-based bioflocculant produced by Bacillus subtilis ZHX3 and its application in the treatment of multiple pollutants

Author:
Mingchen Xia; Han Zhou; Charles Amanze; Lan Hu; Li Shen; Runlan Yu; Yuandong Liu; Miao Chen; Jiaokun Li; Xueling Wu; Guanzhou Qiu; Weimin Zeng
Source:
Chemosphere 2022 v.289 pp. 133185
ISSN:
0045-6535
Subject:
Bacillus subtilis; adsorption; arabinose; decolorization; flocculation; galactose; galacturonic acid; glucose; mannose; molecular weight; polyacrylamide; rhamnose; starch; wastewater treatment; yeast extract
Abstract:
... A high bioflocculant-producing bacterial strain was identified and named Bacillus subtilis ZHX3. Single-factor experiments suggested that 10 g/L starch and 5 g/L yeast extract were optimal for strain ZHX3 to produce bioflocculant MBF-ZHX3. The maximum flocculating rate reached 95.5%, and 3.14 g/L product was extracted after 3 days of cultivation. MBF-ZHX3 was mainly composed of polysaccharides (77 ...
DOI:
10.1016/j.chemosphere.2021.133185

19. A novel two-stage heterotrophic cultivation for starch-to-protein switch to efficiently enhance protein content of Chlorella sp. MBFJNU-17

Author:
Xuehua Xiao; Youcai Zhou; Zhibo Liang; Rongzhao Lin; Mingmin Zheng; Bilian Chen; Yongjin He
Source:
Bioresource technology 2022 v.344 pp. 126187
ISSN:
0960-8524
Subject:
Chlorella; absorption; biomass; biosynthesis; carbon metabolism; fermenters; glucose; microalgae; protein content; starch; technology; urea
Abstract:
... This work aimed to firstly establish an efficient and novel two-stage cultivation process to produce microalgal biomass rich in protein using a heterotrophic Chlorella sp. MBFJNU-17 strain. In the first-stage cultivation, to reduce the glucose and urea utilization, microalga achieved a high biomass at 40 g/L glucose and 1 g/L urea; meantime, the expression from starch biosynthesis genes of microal ...
DOI:
10.1016/j.biortech.2021.126187

20. A polysaccharide from Lycium barbarum L.: Structure and protective effects against oxidative stress and high-glucose-induced apoptosis in ARPE-19 cells

Author:
Jianfei Liu; Yunchun Li; Qiaosheng Pu; Hongdeng Qiu; Duolong Di; Youlong Cao
Source:
International journal of biological macromolecules 2022 v.201 pp. 111-120
ISSN:
0141-8130
Subject:
Lycium barbarum; X-ray diffraction; anion exchange; antioxidants; apoptosis; arabinose; colorimetry; galactose; galacturonic acid; gel chromatography; glucose; glucuronic acid; hyperglycemia; oxidative stress; polysaccharides; rhamnose; thermal stability; thermogravimetry; vision
Abstract:
... Lycium barbarum polysaccharides (LBPs) are beneficial for vision; however, relevant research has mainly focused on entire crude polysaccharides, with the basis and exact structure of the polysaccharide rarely explored. In this study, LICP009-3F-2a, a novel polysaccharide from Lycium barbarum L., was separated and then purified using anion-exchange and size-exclusion chromatography. Structural char ...
DOI:
10.1016/j.ijbiomac.2021.12.139

21. A polysaccharide isolated from Ganoderma lucidum ameliorates hyperglycemia through modulating gut microbiota in type 2 diabetic mice

Author:
Weiming Shao; Chun Xiao; Tianqiao Yong; Yifan Zhang; Huiping Hu; Ting Xie; Rongjie Liu; Longhua Huang; Xiangmin Li; Yizhen Xie; Jumei Zhang; Shaodan Chen; Manjun Cai; Diling Chen; Yuanchao Liu; Xiong Gao; Qingping Wu
Source:
International journal of biological macromolecules 2022 v.197 pp. 23-38
ISSN:
0141-8130
Subject:
Bacteroides; Ganoderma lucidum; Lactobacillus; Ruminococcaceae; blood glucose; endotoxins; fermentation; genes; glucose; glycogen; high fat diet; hyperglycemia; inflammation; insulin; insulin resistance; insulin secretion; intestinal microorganisms; intestines; liver; noninsulin-dependent diabetes mellitus; streptozotocin
Abstract:
... In this study, we reported a thermal stable and non-toxic heteropolysaccharide F31, which decreased the blood glucose of diabetic mice (21.75 mmol/L) induced by high-fat diet (HFD) and streptozotocin (STZ) to 12.56 and 15.18 mmol/L (P < 0.01) at 180 and 60 mg/kg, depicting remarkable hypoglycemic effects of 42.25 and 30.21%. Moreover, F31 repaired islet cells and increased insulin secretion, promo ...
DOI:
10.1016/j.ijbiomac.2021.12.034

22. A remarkable divergent fluorescence response to epimeric monosaccharides by an isoquinoline-derived diboronate

Author:
Taylor A. Garget; Milton J. Kiefel; Todd A. Houston
Source:
Tetrahedron letters 2022 v.94 pp. 153698
ISSN:
0040-4039
Subject:
boronic acids; fluorescence; galactose; glucose; glycols; hexoses
Abstract:
... Herein we report a new boronic acid fluorescent sensor based on 4-isoquinolineboronic acid that has a fluorescent divergent response biologically relevant monosaccharides, glucose and galactose. By analyzing the interactions of this sensor with several alternate sugar forms we have been able to determine how the boronic acid selects diols for binding and how such a molecule could have a positive a ...
DOI:
10.1016/j.tetlet.2022.153698

23. A review on potential anti-diabetic mechanisms of chitosan and its derivatives

Author:
D.N. Priyanka; K.V. Harish Prashanth; R.N. Tharanathan
Source:
Carbohydrate polymer technologies and applications 2022 v.3 pp. 100188
ISSN:
2666-8939
Subject:
blood glucose; chitooligosaccharides; chitosan; diabetes; glucose; glycemic effect; humans; hyperglycemia; insulin resistance; lipid metabolism; molecular weight; polymers
Abstract:
... Diabetes is a highly complex disorder that impacts the quality of human life and the prevailing drugs used for the diabetic management have explicit side effects. There is currently a push for dietary supplements from natural sources, which can serve as a better alternative than the commercially available anti-diabetic medications. This article focuses on the vital mechanisms and blood-glucose low ...
DOI:
10.1016/j.carpta.2022.100188

24. A sensitive and simple HPLC-FLD-based method for the measurement of intracellular glucose uptake

Author:
Lele Yang; Sijia Wu; Jinchao Wei; Jiagang Deng; Xiaotao Hou; Erwei Hao; Lei Zhang; Peng Li
Source:
Food chemistry 2022 v.372 pp. 131218
ISSN:
0308-8146
Subject:
energy; fluorescence; food chemistry; glucose; hepatocytes; mammals; myoblasts
Abstract:
... Glucose is a primary source of energy used in most organisms. Thus, development of reliable approaches to measure intracellular glucose uptake is an important research issue. 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxy-d-glucose (2-NBDG), as a fluorescent glucose derivative, has been widely used to track intracellular glucose uptake by fluorescence imaging and measuring in mammalian ce ...
DOI:
10.1016/j.foodchem.2021.131218

25. A simple and green method for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on personal glucose meter

Author:
Hao Zhang; Zhao-Miao Gong; Yan Li; Feng-Qing Yang
Source:
Enzyme and microbial technology 2022 v.155 pp. 109996
ISSN:
0141-0229
Subject:
acetylcholinesterase; blood glucose; disulfides; enzymatic reactions; glucose; hydrogen peroxide; hydrolysis; hypochlorites; iodides; iodine; oxidation; technology
Abstract:
... A convenient and green method was developed using a personal glucose meter (PGM) for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on the acetylthiocholine iodide (ATCI)-mediated reaction. In this method, acetylcholinesterase catalyzes the hydrolysis of ATCI to generate thiocholine iodide, which can trigger the reduction of K₃[Fe(CN)₆] to K₄[Fe(CN)₆] a ...
DOI:
10.1016/j.enzmictec.2022.109996

26. A simple hydrothermal route for the preparation of novel Na–Y–W nano-oxides and their application in dye degradation

Author:
Saeed Moshtaghi; Masoud Hamadanian; Masoud Salavati-Niasari
Source:
RSC advances 2022 v.12 no.8 pp. 4913-4923
ISSN:
2046-2069
Subject:
cellulose; dyes; energy; fructose; glucose; lactose; photocatalysis; photolysis; starch
Abstract:
... The fabricated NaY(WO₄)₂ was identified through diverse analysis methods. Therefore, to optimize NaY(WO₄)₂ morphology, saccharide carbohydrates were manipulated as a capping agent. In this study, glucose, fructose, lactose, cellulose, and starch were utilized as the capping agents. SEM images show that fructose was the optimal capping agent for achieving uniform and well-shaped nanoparticles. The ...
DOI:
10.1039/d1ra07645k

27. A strain of Saccharomyces cerevisiae with high production of butanol

Author:
Yunxia Gong; Naranzul Tumurbaatar; Junying Zhou; Xiaobao Qi
Source:
European food research & technology 2022 v.248 no.1 pp. 207-217
ISSN:
1438-2377
Subject:
Saccharomyces cerevisiae; butanol; dough; fermentation; flour; food research; glucose; maltose; pH; pulsed-field gel electrophoresis; sucrose
Abstract:
... The paper was aimed to isolate a strain of Saccharomyces cerevisiae with higher alcohol, butanol. 32 strains of S. cerevisiae were isolated and identified from the dough starters from different regions. First, sterile flour solution (SFS) was developed as a substrate, and the HS-SPME-GC/MS technique was used to detect the volatile compounds, especially butanol. Then, gas production rate and acid-p ...
DOI:
10.1007/s00217-021-03874-z

28. A survey of fermentation parameters, bacterial community compositions and their metabolic pathways during the ensiling of sorghum

Author:
Siran Wang; Tao Shao; Junfeng Li; Jie Zhao; Zhihao Dong
Source:
Journal of applied microbiology 2022 v.132 no.5 pp. 3563-3577
ISSN:
1364-5072
Subject:
1-phosphofructokinase; Lactobacillus; Lactococcus; Sorghum bicolor subsp. bicolor; amino acids; ammonium nitrogen; arabinose; bacterial communities; butyric acid; energy; feed quality; glucose; lactic acid; lactic fermentation; metabolites; microbiology; pH; pyruvate kinase; soft dough stage; sorghum silage; surveys; total nitrogen; xylose
Abstract:
... AIMS: To investigate the fermentative products, bacterial community compositions and their metabolic pathways of sorghum (Sorghum dochna Snowden) during ensiling. METHODS AND RESULTS: Sorghum was harvested at soft dough stage and ensiled in laboratory‐scale silos (10 L capacity). Triplicate silos were sampled after 1, 3, 7, 15, 30 and 60 days of ensiling, respectively. The bacterial communities on ...
DOI:
10.1111/jam.15484

29. A touch-actuated glucose sensor fully integrated with microneedle array and reverse iontophoresis for diabetes monitoring

Author:
Yanxiang Cheng; Xia Gong; Jian Yang; Guizhou Zheng; Ying Zheng; Yanjun Li; Yunsheng Xu; Gang Nie; Xi Xie; Meiwan Chen; Changqing Yi; Lelun Jiang
Source:
Biosensors & bioelectronics 2022 v.203 pp. 114026
ISSN:
0956-5663
Subject:
biomarkers; biosensors; blood; diabetes; electrochemistry; glucose; mobile telephones
Abstract:
... The development of non-invasive biosensor for monitoring glucose in interstitial fluid (ISF) is still challenging, because ISF extraction through classical reverse iontophoresis (RI) is limited by low extraction flux and consistency. Here, we developed a touch-actuated biosensor for monitoring glucose in ISF. The biosensor is composed of three main components: 1) the solid microneedle array (MA) f ...
DOI:
10.1016/j.bios.2022.114026

30. AMPK in the brain: its roles in glucose and neural metabolism

Author:
Ranjithmenon Muraleedharan; Biplab Dasgupta
Source:
FEBS journal 2022 v.289 no.8 pp. 2247-2262
ISSN:
1742-464X
Subject:
AMP-activated protein kinase; Alzheimer disease; Parkinson disease; amyotrophic lateral sclerosis; apoptosis; astrocytes; brain; cell viability; energy balance; glucose; glycogen; glycolysis; homeostasis; lactic acid; neurons; pentoses; peripheral nervous system diseases; phosphates; sclerosis
Abstract:
... The adenosine monophosphate‐activated protein kinase (AMPK) is an integrative metabolic sensor that maintains energy balance at the cellular level and plays an important role in orchestrating intertissue metabolic signaling. AMPK regulates cell survival, metabolism, and cellular homeostasis basally as well as in response to various metabolic stresses. Studies so far show that the AMPK pathway is a ...
DOI:
10.1111/febs.16151

31. ATP Purinergic Receptor P2X1-Dependent Suicidal NETosis Induced by Cryptosporidium parvum under Physioxia Conditions

Author:
Seyed Sajjad Hasheminasab; Iván Conejeros; Zahady D. Velásquez; Tilman Borggrefe; Ulrich Gärtner; Faustin Kamena; Anja Taubert; Carlos Hermosilla
Source:
Biology 2022 v.11 no.3 pp. -
ISSN:
2079-7737
Subject:
Cryptosporidium parvum; DNA; Protozoa; acidification; cattle; cryptosporidiosis; elastase; extrusion; fluorescence microscopy; glucose; glycolysis; helminths; hyperoxia; intestines; lactic acid; neutrophils; oocysts; oxygen; oxygen consumption; plasma membrane; purinergic receptors; sporozoites; wildlife
Abstract:
... Cryptosporidiosis is a zoonotic intestinal disease that affects humans, wildlife, and neonatal cattle, caused by Cryptosporidium parvum. Neutrophil extracellular traps (NETs), also known as suicidal NETosis, are a powerful and ancient innate effector mechanism by which polymorphonuclear neutrophils (PMN) battle parasitic organisms like protozoa and helminths. Here, C. parvum oocysts and live sporo ...
DOI:
10.3390/biology11030442

32. Abnormal behavior of chilling injury in postharvest papaya fruit is associated with sugar metabolism

Author:
Yi Zhu; Qun Huang; Yonggui Pan; Zhengke Zhang; Rong Yuan; Yudong Nie
Source:
Journal of food science 2022 v.87 no.3 pp. 919-928
ISSN:
0022-1147
Subject:
abnormal behavior; beta-fructofuranosidase; food science; fructose; fruits; glucose; metabolism; papayas; storage temperature; sucrose; sucrose synthase; sucrose-phosphate synthase
Abstract:
... In the most chilling‐sensitive fruits and vegetables, usually, the lower the storage temperature, the more serious the symptoms of chilling injury (CI). As one of the special cases, papaya fruits at 1℃ show slighter CI symptoms than those at higher storage temperature. Such abnormal CI phenomenon has not received enough attention and its mechanism is not clear. The present study investigated the d ...
DOI:
10.1111/1750-3841.16067

33. Accumulation and conversion of β-carotene and astaxanthin induced by abiotic stresses in Schizochytrium sp.

Author:
Ling Li; Xiuyang Tang; Yangyang Luo; Xuechao Hu; Lujing Ren
Source:
Bioprocess and biosystems engineering 2022 v.45 no.5 pp. 911-920
ISSN:
1615-7591
Subject:
Schizochytrium; antioxidant activity; astaxanthin; bioprocessing; genes; glucose; health services; monosodium glutamate; nutrition; temperature
Abstract:
... Astaxanthin is a kind of ketone carotenoid belonging to tetraterpenoids with an excellent antioxidant activity and it is widely used in nutrition and health-care industries. This study aimed to explore the effect of different abiotic stresses on carotenoid production in Schizochytrium sp. Firstly, the characteristics of carotenoid accumulation were studied in Schizochytrium sp. by monitoring the c ...
DOI:
10.1007/s00449-022-02709-9

34. Acetate-based production of itaconic acid with Corynebacterium glutamicum using an integrated pH-coupled feeding control

Author:
Manuel Merkel; Dirk Kiefer; Marc Schmollack; Bastian Blombach; Lars Lilge; Marius Henkel; Rudolf Hausmann
Source:
Bioresource technology 2022 v.351 pp. 126994
ISSN:
0960-8524
Subject:
Aspergillus terreus; Corynebacterium glutamicum; acetates; biobased products; biotechnology; carbon; fungi; genes; glucose; isocitrate dehydrogenase; itaconic acid; titration
Abstract:
... To date, most bio-based products of industrial biotechnology stem from sugar-based carbon sources originating from food and feed competing resources. Exemplary for bioproducts converted from glucose, the potential C5 platform chemical itaconic acid is presently produced by the filamentous fungus Aspergillus terreus. Here, an engineered strain of the industrial platform organism Corynebacterium glu ...
DOI:
10.1016/j.biortech.2022.126994

35. Achene mucilage formation process and extrusion from hydrated pericarp of Mirabilis himalaica

Author:
Qingqing Huang; Lu Zhang; Xiaozhong Lan; Yuzhen Chen; Cunfu Lu
Source:
Horticultural plant journal 2022 v.8 no.2 pp. 251-260
ISSN:
2468-0141
Subject:
Mirabilis himalaica; achenes; alpine plants; climate; color; exocarp; extrusion; galactose; gels; germination; glucose; horticultural crops; hydrophilicity; ion exchange chromatography; mannose; mucilages; rhamnose; seedling growth; texture; trehalose; China
Abstract:
... Myxospermy is an important feature of achenes of the alpine plant Mirabilis himalaica, and the achene mucilage increases the germination rate and early seedling growth during exposure to abiotic stresses, which has important functions that allow M. himalaica to survive the extreme climate of the Tibet Plateau. However, achene formation and mucilage extrusion are poorly understood. In the present s ...
DOI:
10.1016/j.hpj.2021.10.001

36. Acidocétose sévère après un régime cétogène chez une jeune femme allaitante non-diabétique

Author:
D. Bedock; N. El Boueiz; A. Beurton; M. Decavele; J.-M. Oppert; P. Faucher
Source:
Nutrition clinique et métabolisme 2022 v.36 no.1 pp. 68-71
ISSN:
0985-0562
Subject:
acid-base balance; blood serum; breast feeding; diabetes; energy expenditure; glucose; ketogenic diet; ketosis; lactation; low calorie diet; patients; physical activity; pregnancy; protein intake; therapeutics; weight loss; women
Abstract:
... Ketogenic diet, used in therapeutics in refractory epilepsies, is in general a low-calorie diet, with low-carbohydrate, high-fat and adequate protein intake, inducing ketosis. It use has spread to the general population because it helps achieve rapid weight loss. Ketosis induced by this diet may in some cases progress to ketoacidosis, for example during acute illness or in specific settings where ...
DOI:
10.1016/j.nupar.2021.10.001

37. Acrylamide formation in red-, purple- and yellow-fleshed potatoes by frying and baking

Author:
Matyáš Orsák; Zora Kotíková; Klára Podhorecká; Jaromír Lachman; Pavel Kasal
Source:
Journal of food composition and analysis 2022 v.110 pp. 104529
ISSN:
0889-1575
Subject:
acrylamides; asparagine; chlorogenic acid; food composition; fructose; glucose; health promotion; heat treatment; phytochemicals; potatoes; sucrose; temperature
Abstract:
... Potatoes are a significant source of essential macronutrients and many other health-promoting phytochemicals. However, under thermal processing, undesirable harmful acrylamide might be formed. In the present study, the content of acrylamide (LC–ESI-MS/MS) after baking and frying in thirteen colored potato varieties was investigated. Asparagine (LC–ESI-MS/MS), glucose, fructose, sucrose (HPLC–RI) a ...
DOI:
10.1016/j.jfca.2022.104529

38. Actinobacteria isolated from wastewater treatment plants located in the east-north of Algeria able to degrade pesticides

Author:
Oumeima Boufercha; Irina S. Moreira; Paula M. L. Castro; Allaoueddine Boudemagh
Source:
World journal of microbiology & biotechnology 2022 v.38 no.6 pp. 105
ISSN:
0959-3993
Subject:
2,4-dichlorophenol; Streptomyces; bacterial growth; biodegradation; bioremediation; biotechnology; carbon; glucose; liquids; public health; thiamethoxam; wastewater treatment; water pollution; Algeria
Abstract:
... The pollution of water resources by pesticides poses serious problems for public health and the environment. In this study, Actinobacteria strains were isolated from three wastewater treatment plants (WWTPs) and were screened for their ability to degrade 17 pesticide compounds. Preliminary screening of 13 of the isolates of Actinobacteria allowed the selection of 12 strains with potential for the ...
DOI:
10.1007/s11274-022-03282-9

39. Acute insulin-responsive hyperglycemia and hypocalcemia in Theileria spp. infected goat

Author:
Krishna Remya; Y. Ajith; J. Parvathy; Varuna P. Panicker; P. Preena; V.R. Ambily; Thankachan Ancy; Francis Anjaly; N. Madhavan Unny; Usha Narayana Pillai
Source:
Veterinary Parasitology: Regional Studies and Reports 2022 v.27 pp. 100668
ISSN:
2405-9390
Subject:
Theileria; anorexia; body water; calcium; clinical examination; glucose; goats; hyperglycemia; hypocalcemia; mucosa; neck; theileriosis; therapeutics; thrombocytopenia; veterinary parasitology
Abstract:
... Theileriosis can be manifested in appreciably variable clinical forms among domestic ruminants and may often become life-threatening. The present report narrates, the quick remarkable clinical recovery of a lactating goat infected with Theileria spp., exhibiting acute insulin-responsive hyperglycemia and hypocalcemia, by providing intensive therapy. A four year old doe was presented with the compl ...
DOI:
10.1016/j.vprsr.2021.100668

40. Acute responses of stevia and d-tagatose intake on metabolic parameters and appetite/satiety in insulin resistance

Author:
Verónica Sambra; Isabella A. Vicuña; Kathleen M. Priken; Selva L. Luna; Daniela A. Allendes; Paula M. Godoy; Victoria Novik; Claudia A. Vega
Source:
Clinical nutrition ESPEN 2022 pp. -
ISSN:
2405-4577
Subject:
Stevia; appetite; blood glucose; c-peptide; carbohydrate metabolism; clinical nutrition; cross-over studies; food intake; glucose; insulin resistance; satiety; tagatose
Abstract:
... To examine the effects of d-tagatose or stevia preloads on carbohydrate metabolism markers after an oral glucose load, as well as subjective and objective appetite in women with insulin resistance (IR). Randomized controlled crossover study. Women with IR without T2DM (n = 33; aged 23.4 ± 3.8; BMI 28.1 ± 3.4 kg × m⁻²) underwent three oral glucose loads (3 h each) on three different days. Ten min b ...
DOI:
10.1016/j.clnesp.2022.04.018

41. Adansonia digitata L. (Baobab Fruit) Effect on Postprandial Glycemia in Healthy Adults: A Randomized Controlled Trial

Author:
Keyla Rita; Maria Alexandra Bernardo; Maria Leonor Silva; José Brito; Maria Fernanda Mesquita; Ana Maria Pintão; Margarida Moncada
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
Adansonia digitata; antioxidant activity; blood glucose; food composition; fruits; glucose; glucose tolerance tests; hypoglycemic agents; nitric oxide; polyphenols; randomized clinical trials; t-test; therapeutics; Africa
Abstract:
... Baobab fruits have been traditionally used in Africa due to their therapeutic properties attributed to their high polyphenol content. The aim of the study was to investigate the effect of baobab fruit on postprandial glycaemia in healthy adults and to measure its bioactive compounds and antioxidant activity. The study (NCT05140629) was conducted on 31 healthy subjects. The participants were random ...
DOI:
10.3390/nu14020398

42. Addition of iron to agricultural topsoil and subsoil is not an effective C sequestration strategy

Author:
Erik S. Button; David R. Chadwick; David L. Jones
Source:
Geoderma 2022 v.409 pp. 115646
ISSN:
0016-7061
Subject:
arable soils; carbon; carbon dioxide; carbon sequestration; carbonates; citrates; glucose; iron; microbial biomass; mineralization; pH; soil acidification; soil organic matter; soil solution; subsoil; topsoil
Abstract:
... The interaction of soil organic matter (SOM) with Fe-containing minerals represents a key mechanism that promotes carbon (C) stabilisation in soil. The addition of Fe-rich industrial by-products to soil may therefore help accelerate C storage. Our understanding of the effects of exogenous Fe addition (Fe (oxy)hydroxide vs. Fe chloride) on SOM dynamics and C dynamics in agricultural soils, especial ...
DOI:
10.1016/j.geoderma.2021.115646

43. Advances in FePt-involved nano-system design and application for bioeffect and biosafety

Author:
Zunfu Hu; Qiulian Wei; Huimin Zhang; Weina Tang; Yunkai Kou; Yunqiang Sun; Zhichao Dai; Xiuwen Zheng
Source:
Journal of materials chemistry B 2022 v.10 no.3 pp. 339-357
ISSN:
2050-7518
Subject:
biocompatibility; biosafety; cancer therapy; computed tomography; drugs; glucose; health services; immunotherapy; magnetism; nanocomposites; nanomedicine; photochemotherapy; radiotherapy
Abstract:
... The rapid development and wide application of nanomaterial-involved theranostic agents have drawn surging attention for improving the living standard of humankind and healthcare conditions. In this review, recent developments in the design, synthesis, biocompatibility evaluation and potential nanomedicine applications of FePt-involved nano-systems are summarized, especially for cancer theranostic ...
DOI:
10.1039/d1tb02221k

44. Aerobic and anaerobic biodegradation of BDE-47 by bacteria isolated from an e-waste-contaminated site and the effect of various additives

Author:
Lili Huo; Chenghao Zhao; Tianyuan Gu; Ming Yan; Hua Zhong
Source:
Chemosphere 2022 v.294 pp. 133739
ISSN:
0045-6535
Subject:
2,4-dichlorophenol; Bacillus cereus; acetic acid; aerobes; biodegradation; bisphenol A; carbon; electronic wastes; ethanol; glucose; half life; hydroquinone; octoxynol; polysorbates; rhamnolipids; toluene; yeast extract
Abstract:
... Degradation experiments are conducted to specifically compare the degradation of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) by aerobic and anaerobic strains isolated from real e-waste sites contaminated by BDE-47. The effect of carbon sources, inducers and surfactants on the degradation was examined to strengthen such a comparison. An aerobic strain, B. cereus S1, and an anaerobic strain, A. faec ...
DOI:
10.1016/j.chemosphere.2022.133739

45. Agaricus blazei Murill polysaccharides alleviate oxidative stress and inflammatory responses against liver and lung injury

Author:
Wenshuai Wang; Min Liu; Mengyu Zhang; Wenxue Sun; Jianjun Zhang; Le Jia
Source:
Food bioscience 2022 v.47 pp. 101645
ISSN:
2212-4292
Subject:
Agaricus subrufescens; death; glucose; interleukin-6; liver; lungs; mushrooms; oxidative stress; survival rate; zymosan
Abstract:
... As a kind of well-known edible mushroom, the medicinal values of Agaricus blazei Murill also have been well acknowledged. There is no efficient treatment strategy for multiple organ dysfunction syndrome (MODS) so far, a crucial cause of clinical death. The present work was designed to evaluate the beneficially protective effects of Agaricus blazei Murill polysaccharides (ABMP) on liver and lung ag ...
DOI:
10.1016/j.fbio.2022.101645

46. Agrocinopine C, a Ti-plasmid-coded enzyme-product, is a 2-O, 6-O linked phosphodiester of D-Glucose and sucrose

Author:
Robert E. Asenstorfer; Maarten H. Ryder; Graham P. Jones
Source:
Phytochemistry 2022 v.194 pp. 113013
ISSN:
0031-9422
Subject:
Agrobacterium radiobacter; Helianthus annuus; aldehydes; antibiotics; crown galls; glucose; moieties; plant biochemistry; plasmids; sucrose; toxicity
Abstract:
... Agrocinopine C is a small molecule found in crown gall tumours induced by pathogenic Agrobacterium radiobacter carrying the tumour-inducing plasmid pTi Bo542. This phosphodiester opine was isolated (at 0.02 g/100 g fresh wt.) from sunflower (Helianthus annuus L.) galls. It is structurally related to agrocinopine A and is a glucose-2-phosphodiester linked to the C6-hydroxy-methyl group of the gluco ...
DOI:
10.1016/j.phytochem.2021.113013

47. Aldehyde N,N-dimethylhydrazone-based fluorescent substrate for peroxidase-mediated assays

Author:
Soyeon Yoo; Sudeok Kim; Sangyeon Jeon; Min Su Han
Source:
RSC advances 2022 v.12 no.14 pp. 8668-8673
ISSN:
2046-2069
Subject:
aldehydes; blood serum; chemical species; fluorescence; glucose; humans; pH; peroxidase
Abstract:
... Numerous assays based on peroxidase activity have been developed for the detection of analytes due to the various optical peroxidase substrates. However, most substrates are sensitive to light and pH and are over-oxidized in the presence of excess H₂O₂. In this study, 2-((6-methoxynaphthalen-2-yl)methylene)-1,1-dimethylhydrazine (MNDH), a fluorescent peroxidase substrate prepared from naphthalene- ...
DOI:
10.1039/d2ra00087c

48. Algal cultivation strategies for enhancing production of Chlorella sorokiniana IG-W-96 biomass and bioproducts

Author:
Arash Karimian; Mahmood A. Mahdavi; Reza Gheshlaghi
Source:
Algal research 2022 v.62 pp. 102630
ISSN:
2211-9264
Subject:
Chlorella sorokiniana; acetates; algae culture; biobased products; biomass production; carotenoids; economic sustainability; feedstocks; glucose; glycerol; lipids; microalgae; organic carbon; protein synthesis; research
Abstract:
... Microalgae may prove to be a reliable feedstock for the production of commodity bioproducts if their production can be made economically viable. Such a goal is achievable by diversity in products and maximizing production yield. In the present study, the cumulative impact of trophic modes, organic carbon sources (acetate, glucose, and glycerol), and operation modes on the production of Chlorella s ...
DOI:
10.1016/j.algal.2022.102630

49. Alizarin-functionalized organic-inorganic silane coatings for the development of wearable textile sensors

Author:
Valentina Trovato; Alessio Mezzi; Marco Brucale; Giuseppe Rosace; Maria Rosaria Plutino
Source:
Journal of colloid and interface science 2022 v.617 pp. 463-477
ISSN:
0021-9797
Subject:
alizarin; color; cotton; cotton fabric; deprotonation; durability; epoxides; glucose; pH; protonation; reflectance; silane; silica; temperature
Abstract:
... The broad detection properties of alizarin, not only concerning pH variations but also temperature, glucose and health-like relevant cations alterations, make it a molecule of great scientific interest, particularly for developing multifunctional wearable sensors. Herein, the alizarin red S dyestuff is bonded with trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane, as a sol–gel precursor, to function ...
DOI:
10.1016/j.jcis.2022.03.006

50. Alleviation of Dyslipidemia via a Traditional Balanced Korean Diet Represented by a Low Glycemic and Low Cholesterol Diet in Obese Women in a Randomized Controlled Trial

Author:
Min Jung Kim; Sunmin Park; Hye Jeong Yang; Phil-Kyung Shin; Haeng Jeon Hur; Seon-Joo Park; Kyun-Hee Lee; Moonju Hong; Jin Hee Kim; Sang-Woon Choi; Hae-Jeung Lee; Myung-Sunny Kim
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
3-hydroxybutyric acid; antioxidants; blood serum; cholesterol; energy intake; glucose; glutamic acid; glutathione; glycemic index; hyperlipidemia; insulin; insulin resistance; lipid metabolism; lipoproteins; low cholesterol diet; metabolites; randomized clinical trials; triacylglycerols; tryptophan; tyrosine; waist circumference
Abstract:
... A traditional balanced Korean diet (K-diet) may improve energy, glucose, and lipid metabolism. To evaluate this, we conducted a randomized crossover clinical trial, involving participants aged 30–40 years, who were randomly assigned to two groups—a K-diet or westernized Korean control diet daily, with an estimated energy requirement (EER) of 1900 kcal. After a 4-week washout period, they switched ...
DOI:
10.3390/nu14020235

51. Alleviation of the adverse effects of drought stress using a desert adapted endophytic fungus and glucose in tomato

Author:
Mehdi Ghabooli; Esmaeel Kaboosi
Source:
Rhizosphere 2022 v.21 pp. 100481
ISSN:
2452-2198
Subject:
Solanum lycopersicum; ascorbate peroxidase; biomass; carotenoids; catalase; chlorophyll; drought; drought tolerance; electrolyte leakage; endophytes; fungi; glucose; hydrogen peroxide; malondialdehyde; peroxidase; phosphorus; plant growth; potassium; proline; rhizosphere; superoxide dismutase; tomatoes; water stress
Abstract:
... Beneficial interaction of plants with fungi is one strategy for adapting to environmental stresses like drought. Serendipita indica, an endophytic root fungus, promotes plant growth and enhances tolerance to abiotic stresses. The present study aimed to investigate the amelioration of drought stress in tomato (Solanum lycopersicum L.) upon S. indica and glucose application through morpho-physiologi ...
DOI:
10.1016/j.rhisph.2022.100481

52. Almond consumption decreases android fat mass percentage in adults with high android subcutaneous adiposity but does not change HbA1c in a randomised controlled trial

Author:
Stephanie R. Hunter; Robert V. Considine; Richard D. Mattes
Source:
British journal of nutrition 2022 v.127 no.6 pp. 850-861
ISSN:
1475-2662
Subject:
adipose tissue; adiposity; almonds; appetite; blood; blood glucose; breakfast; energy intake; food quality; glucose; hyperlipidemia; overweight; randomized clinical trials
Abstract:
... The purpose of this study was to determine if the mixed evidence of almond consumption on HbA1c stems from testing people with different body fat distributions (BFD) associated with different risks of glucose intolerance. A 6-month randomised controlled trial in 134 adults was conducted. Participants were randomly assigned to the almond (A) or control (C) group based on their BFD. Those in the alm ...
DOI:
10.1017/S0007114521001495

53. Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities, Molecular Docking, and Antioxidant Capacities of Plectranthus ecklonii Constituents

Author:
Ninon G. E. R. Etsassala; Jelili A. Badmus; Jeanine L. Marnewick; Samuel Egieyeh; Emmanuel. I. Iwuoha; Felix Nchu; Ahmed A. Hussein
Source:
Antioxidants 2022 v.11 no.2 pp. -
ISSN:
2076-3921
Subject:
Plectranthus; absorption; alpha-amylase; alpha-glucosidase; antioxidant activity; antioxidants; blood glucose; digestion; diterpenoids; epigallocatechin gallate; glucose; insulin; insulin secretion; risk
Abstract:
... Shortage in insulin secretion or degradation of produced insulin is the principal characteristic of the metabolic disorder of diabetes mellitus (DM). However, because the current medications for the treatment of DM have many detrimental side effects, it is necessary to develop more effective antidiabetic drugs with minimal side effects. Alpha-glucosidase and alpha-amylase inhibitors are directly i ...
DOI:
10.3390/antiox11020378

54. Alternating red and blue irradiation affects carbohydrate accumulation and sucrose metabolism in butterhead lettuce

Author:
Xiao-Li Chen; Li-chun Wang; You-Li Li; Qi-Chang Yang; Wen-zhong Guo
Source:
Scientia horticulturae 2022 v.302 pp. 111177
ISSN:
0304-4238
Subject:
Lactuca sativa var. capitata; beta-fructofuranosidase; biomass; blue light; crude fiber; electric energy consumption; electricity; fructose; gene expression; glucose; irradiation; lettuce; light intensity; metabolism; photons; red light; sucrose; sucrose synthase; sucrose-phosphate synthase; sugar content; sweetness; taste
Abstract:
... Sucrose metabolism and carbohydrate accumulation were evaluated in butterhead lettuce cultured under alternating red light (R) and blue light (B) irradiance. The R/B treatments were respectively R/B(5 m) (i.e. R 5 min/B 5 min), R/B(10 m), R/B(15 m), R/B(30 m) and R/B(60 m). Meanwhile, concurrent R and B (RB) as well as monochromatic R (R) and monochromatic B (B) were conducted. Compared with concu ...
DOI:
10.1016/j.scienta.2022.111177

55. Ameliorative effects of dietary Vitamin‐C on growth performance and hemato‐biochemical response of sodium fluoride‐intoxicated Amur Carp, Cyprinus carpio haematopterus

Author:
Rajinder Kaur; Munish Batra; Tarang Kumar Shah; Amita Saxena
Source:
Aquaculture research 2022 v.53 no.7 pp. 2895-2909
ISSN:
1355-557X
Subject:
Cyprinus carpio; albumins; aquaculture; ascorbic acid; blood proteins; body weight; carp; creatinine; diet; globulins; glucose; growth performance; growth retardation; research; sodium; sodium fluoride; toxicity; triacylglycerols
Abstract:
... This study aimed to assess the ameliorative dietary effect of vitamin‐C against sodium fluoride (NaF)‐induced toxicity on growth and haemato‐biochemical parameters in Amur carp. A total of 150 fish (average body weight 169 ± 0.69 g) were randomly distributed into five groups (with three triplicates) including G1 (control); G2 (NaF exposure @100 ppm); G3 (vitamin‐C supplemented diet @100 ppm); G4 ( ...
DOI:
10.1111/are.15805

56. An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles

Author:
Sónia Rocha; Natália Aniceto; Rita C. Guedes; Hélio M. T. Albuquerque; Vera L. M. Silva; Artur M. S. Silva; Maria Luísa Corvo; Eduarda Fernandes; Marisa Freitas
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
adverse effects; computer simulation; flavonoids; glucose; glycogen; glycogenolysis; hydrogen; hydroxylation; hypoglycemia; noninsulin-dependent diabetes mellitus; phosphorylase; pyrazoles; risk reduction; structure-activity relationships
Abstract:
... Glycogen phosphorylase (GP) is a key enzyme in the glycogenolysis pathway. GP inhibitors are currently under investigation as a new liver-targeted approach to managing type 2 diabetes mellitus (DM). The aim of the present study was to evaluate the inhibitory activity of a panel of 52 structurally related chromone derivatives; namely, flavonoids, 2-styrylchromones, 2-styrylchromone-related derivati ...
DOI:
10.3390/nu14020306

57. An Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer

Author:
Faik Gökalp
Source:
Nutrition and cancer 2022 v.74 no.2 pp. 515-519
ISSN:
1532-7914
Subject:
blood; cancer therapy; density functional theory; fructose; galactose; glucose; nutrition; prediction; transportation
Abstract:
... The monosaccharides, glucose, fructose and galactose, are the most common and simplest forms of carbohydrates. The aim of this study was to determine the uptake of glucose as a potential therapeutic target agent for cancer treatment. The stability and transportation calculations of the monosaccharides were carried out in the blood phase by using the density functional theory and docking. The react ...
DOI:
10.1080/01635581.2021.1895233

58. An actin‐like protein PoARP9 involves in the regulation of development and cellulase and amylase expression in Penicillium oxalicum

Author:
Gen Xu; Hao Guo; Mengdi Yan; Zhilei Jia; Zhonghai Li; Mei Chen; Xiaoming Bao
Source:
Journal of applied microbiology 2022 v.132 no.4 pp. 2894-2905
ISSN:
1364-5072
Subject:
Penicillium oxalicum; amylases; carbon; cellulose; chromatin; endo-1,4-beta-glucanase; genes; glucose; microbiology; starch; transcription (genetics)
Abstract:
... AIMS: In eukaryotic cells, chromatin remodelling complexes are essential for the accessibility of transcription factors to the specific regulating regions of downstream genes. Here, we identified an actin‐like protein PoARP9 in cellulase production strain Penicillium oxalicum 114‐2, which was an essential member of SWI/SNF complex. To investigate the physiological function of PoARP9 in transcripti ...
DOI:
10.1111/jam.15466

59. An automated all-in-one system for carbohydrate tracking, glucose monitoring, and insulin delivery

Author:
Hen-Wei Huang; Siheng Sean You; Luca Di Tizio; Canchen Li; Erin Raftery; Claas Ehmke; Christoph Steiger; Junwei Li; Adam Wentworth; Ian Ballinger; Declan Gwynne; Kewang Nan; Jia Y. Liang; Jason Li; James D. Byrne; Joy Collins; Siddartha Tamang; Keiko Ishida; Florencia Halperin; Giovanni Traverso
Source:
Journal of controlled release 2022 v.343 pp. 31-42
ISSN:
0168-3659
Subject:
automation; blood glucose; computer vision; diabetes mellitus; glucose; glycemic control; insulin; insulin replacement therapy; titration
Abstract:
... Glycemic control through titration of insulin dosing remains the mainstay of diabetes mellitus treatment. Insulin therapy is generally divided into dosing with long- and short-acting insulin, where long-acting insulin provides basal coverage and short-acting insulin supports glycemic excursions associated with eating. The dosing of short-acting insulin often involves several steps for the user inc ...
DOI:
10.1016/j.jconrel.2022.01.001

60. An efficient multi-enzyme cascade platform based on mesoporous metal-organic frameworks for the detection of organophosphorus and glucose

Author:
Xiyue Cao; Yanmei Guo; Mu Zhao; Jie Li; Chonglin Wang; Jianfei Xia; Tingting Zou; Zonghua Wang
Source:
Food chemistry 2022 v.381 pp. 132282
ISSN:
0308-8146
Subject:
Chinese cabbage; acephate; acetylcholine; acetylcholinesterase; chlorides; choline oxidase; color; colorimetry; coprecipitation; detection limit; food chemistry; glucose; peroxidase; porous media
Abstract:
... An efficient colorimetric detection platform based on multi-enzyme cascade has been developed for detection of organophosphorus. Firstly, the dual-enzyme platform was prepared and applied for sensitive glucose detection (detection limit 0.32 μM). And then three enzymes, including acetylcholinesterase, horseradish peroxidase and choline oxidase were encapsulated in cruciate flower-like zeolitic imi ...
DOI:
10.1016/j.foodchem.2022.132282

61. An efficient strategy to improve enzymatic hydrolysis of naked oat straw pretreated by Irpex lacteus

Author:
Menghu Zheng; Rongrong Li; Yan Wang; Fuyu Yang; Chuncheng Xu
Source:
Bioprocess and biosystems engineering 2022 v.45 no.1 pp. 227-236
ISSN:
1615-7591
Subject:
Avena nuda; Irpex lacteus; Phlebia; acid insoluble lignin; arabinose; bioprocessing; cellulose; enzymatic hydrolysis; fermentation; glucose; hydrolysis; lignin peroxidase; oat straw; sugar content; xylose
Abstract:
... The objective of this study was aiming at developing an efficient strategy to promote enzymatic hydrolysis of naked oat straw and deciphering the potential mechanism. Irpex lacteus and Phlebia acerina were employed to inoculated on the naked oat straw for 4 weeks which the changes of fiber components, fermentation losses, lignin-degrading enzymes production pattern were determined weekly. Furtherm ...
DOI:
10.1007/s00449-021-02652-1

62. An fgf21-like gene from swamp eel (Monopterus albus): Recombinant expression and its potential roles in glucose and lipid homeostasis

Author:
Shuting Zheng; Jianfen Wu; Shenghan Xiang; Yuwei Zang; Dan Kong; Xiping Wei; Wenxiu Sun; Wei Li
Source:
Comparative biochemistry and physiology 2022 v.267 pp. 111170
ISSN:
1095-6433
Subject:
Monopterus albus; blood glucose; blood serum; carboxy-lyases; cholesterol; energy balance; fibroblast growth factor receptor 1; fibroblast growth factors; gene expression; genes; genetic vectors; glucose; glucose transporters; homeostasis; insulin-dependent diabetes mellitus; lipid metabolism; liver; mice; sequence analysis; swamps; triacylglycerols
Abstract:
... Fibroblast growth factor 21 (FGF21) plays important roles in the regulation of glucose and lipid metabolism and energy balance in mammals. In this study, the full-length cDNA of swamp eel fgf21 was cloned. Sequence analysis showed that swamp eel FGF21 displayed high similarity with FGF21 of other vertebrates. Subsequently, a prokaryotic expression vector for swamp eel fgf21 was constructed, and re ...
DOI:
10.1016/j.cbpa.2022.111170

63. An investigation of the suitability of melissopalynology to authenticate Jarrah honey

Author:
Md Khairul Islam; Ivan Lozada Lawag; Kathryn J. Green; Tomislav Sostaric; Katherine A. Hammer; Lee Yong Lim; Cornelia Locher
Source:
Current research in food science 2022 v.5 pp. 506-514
ISSN:
2665-9271
Subject:
Eucalyptus marginata; Eucalyptus pilularis; antioxidant activity; brix; electrical conductivity; flowers; food science; fructose; glucose; honey; melissopalynology; pH; phytochemicals; pollen; pollen analysis; refractive index; research; water content
Abstract:
... This study reports on the analysis of eleven Jarrah (Eucalyptus marginata) honeys, of which nearly half (n = 5) were re-classified as Blackbutt (E. patens) honey on the grounds of the predominant flower pollen identified by melissopalynology. Based on a comprehensive analysis of the honeys' physico- and phytochemical characteristics and antioxidant activity data, taking into account pH, electrical ...
DOI:
10.1016/j.crfs.2022.02.014

64. Analysis of glucose and xylose metabolism in new indigenous Meyerozyma caribbica strains isolated from corn residues

Author:
Viviani Tadioto; Letícia M. Milani; Évelyn T. Barrilli; Cristina W. Baptista; Letícia Bohn; Aline Dresch; Ricardo Harakava; Odinei Fogolari; Guilherme M. Mibielli; João P. Bender; Helen Treichel; Boris U. Stambuk; Caroline Müller; Sérgio L. Alves Jr.
Source:
World journal of microbiology & biotechnology 2022 v.38 no.2 pp. 35
ISSN:
0959-3993
Subject:
Meyerozyma caribbica; acetic acid; batch fermentation; biotechnology; corn; ethanol; glucose; hydrolysates; inoculum; xylitol; xylose
Abstract:
... Aiming to broaden the base of knowledge about wild yeasts, four new indigenous strains were isolated from corn residues, and phylogenetic-tree assemblings on ITS and LSU regions indicated they belong to Meyerozyma caribbica. Yeasts were cultivated under full- and micro-aerobiosis, starting with low or high cell-density inoculum, in synthetic medium or corn hydrolysate containing glucose and/or xyl ...
DOI:
10.1007/s11274-021-03221-0

65. Analyzing the minor volatilome of Torulaspora delbrueckii in an alcoholic fermentation

Author:
Minami Ogawa; Florin Vararu; Jaime Moreno-Garcia; Juan Carlos Mauricio; Juan Moreno; Teresa Garcia-Martinez
Source:
European food research & technology 2022 v.248 no.2 pp. 613-624
ISSN:
1438-2377
Subject:
Saccharomyces cerevisiae; Torulaspora delbrueckii; acetates; alcoholic fermentation; beers; butyrates; consumer preferences; flame ionization; food industry; food research; glucose; mass spectrometry; mead; metabolites; odors; yeasts
Abstract:
... Torulaspora delbrueckii is an emerging yeast species in the beverage and food industry that is suitable for alcoholic fermentation and to improve the organoleptic quality of wine, beer, mead, and other beverages. Modern consumer preference toward new flavors and products drives the application of T. delbrueckii to ferment less traditional fruits and vegetables. Thus, it has become increasingly rel ...
DOI:
10.1007/s00217-021-03910-y

66. Angiotensin-(1−7) improves diabetes mellitus-induced erectile dysfunction in rats by regulating nitric oxide synthase levels

Author:
Yi Xu; Fang Zhang; Chunhui Li; Huiyao Hao; Yongmei Hao
Source:
Peptides 2022 v.151 pp. 170765
ISSN:
0196-9781
Subject:
animal models; antagonists; calcium; electrical treatment; endothelial nitric oxide synthase; flow cytometry; fluorescent antibody technique; glucose; inducible nitric oxide synthase; malondialdehyde; noninsulin-dependent diabetes mellitus; oxidative stress; pathogenesis; peptides; smooth muscle
Abstract:
... This study explores the role of inducible nitric oxide synthase (iNOS) in the pathogenesis of diabetes mellitus-induced erectile dysfunction (DMED) and the effect of angiotensin 1–7 (Ang- [1–7]) on NOS levels. A type 2 diabetes mellitus (DM) rat model was established. Erectile function was assessed by measuring intracavernous pressure and mean arterial pressure after electrical stimulation. The ex ...
DOI:
10.1016/j.peptides.2022.170765

67. Animal Welfare and Food Safety When Slaughtering Cattle Using the Gunshot Method

Author:
Jan Hultgren; Katrin J. Schiffer; Jakub Babol; Charlotte Berg
Source:
Animals 2022 v.12 no.4 pp. -
ISSN:
2076-2615
Subject:
Hereford; animal welfare; beef; blood; consciousness; cortisol; farms; food safety; glucose; herds; lactic acid; meat quality; slaughterhouses
Abstract:
... Transporting cattle from farm to slaughterhouse is often stressful for the animal, which can impair the meat quality. With the gunshot method, the animal is stunned with a rifle shot while together with familiar herd members in their home environment, exsanguinated and transported to a nearby slaughterhouse. Aiming to assess the consequences for animal welfare and food safety, 20 Hereford steers a ...
DOI:
10.3390/ani12040492

68. Anti-Diabetic Activity of Bioactive Compound Extracted from Spondias mangifera Fruit: In-Vitro and Molecular Docking Approaches

Author:
Mohammad Khalid; Mohammed H. Alqarni; Abdulrhman Alsayari; Ahmed I. Foudah; Tariq M. Aljarba; Mohammad Mukim; Mubarak A. Alamri; Shahabe Saquib Abullais; Shadma Wahab
Source:
Plants 2022 v.11 no.4 pp. -
ISSN:
2223-7747
Subject:
Spondias pinnata; alpha-amylase; alpha-glucosidase; antioxidants; beta-sitosterol; bioactive compounds; chemical constituents of plants; computer simulation; databases; diabetes; diodes; flavor; fruit extracts; fruits; glucose; glycemic effect; lipid peroxidation; metformin; oleanolic acid; prediction; provenance; traditional medicine; yeasts; India
Abstract:
... Spondias mangifera is a drupaceous fruit popular for its flavour and health advantages. There is little scientific knowledge about S. mangifera, despite its widespread usage in traditional medicine, in the North-Eastern region of India. Inhibiting the key carbohydrate hydrolysing enzymes is one of the strategies for managing diabetes. Therefore, this study studied the antioxidant and anti-diabetic ...
DOI:
10.3390/plants11040562

69. Antibacterial Cascade Catalytic Glutathione-Depleting MOF Nanoreactors

Author:
Xi Zhou; Shuai Zhang; Yan Liu; Jiashen Meng; Muxue Wang; Yaoji Sun; Linbo Xia; Zhaozhi He; Wenxin Hu; Lei Ren; Zhiwei Chen; Xingcai Zhang
Source:
ACS applied materials & interfaces 2022 v.14 no.9 pp. 11104-11115
ISSN:
1944-8252
Subject:
bacterial infections; coordination polymers; death; glucose; glutathione; pH; reactive oxygen species; therapeutics; toxicity
Abstract:
... Nanozymes with peroxidase-like activity have great application potential in combating pathogenic bacterial infections and are expected to become an alternative to antibiotics. However, the near-neutral pH and high glutathione (GSH) levels in the bacterial infection microenvironment severely limit their applications in antibacterial therapy. In this work, a metal–organic framework (MOF)-based casca ...
DOI:
10.1021/acsami.1c24231

70. Anticipating global warming effects: A comprehensive study of drought impact of both flax plants and fibres

Author:
Alessia Melelli; Sylvie Durand; Camille Alvarado; Antoine Kervoëlen; Loïc Foucat; Marie Grégoire; Olivier Arnould; Xavier Falourd; Franck Callebert; Pierre Ouagne; Audrey Geairon; Sylviane Daniel; Frédéric Jamme; Caroline Mauve; Bertrand Gakière; Alain Bourmaud; Johnny Beaugrand
Source:
Industrial crops and products 2022 v.184 pp. 115011
ISSN:
0926-6690
Subject:
Linum usitatissimum; biodegradability; carbon; cultivars; drought; environmental impact; fabrics; fiber quality; flax; fluorescence; glucose; humans; lignin content; mannose; plant growth; polysaccharides; protein content; rain; renewable resources; tryptophan; tyrosine; water stress
Abstract:
... Currently, the effects of global warming are one of the most important topics on the agendas of all governments and international economic and scientific organisations on the planet. Temperatures and rainfall will be especially subjected to increasing deregulation, and thus crop yields will be affected according to geographic location. Cellulosic materials, such as bast fibres, are considered one ...
DOI:
10.1016/j.indcrop.2022.115011

71. Antidiabetic Effects of Pediococcus acidilactici pA1c on HFD-Induced Mice

Author:
Miriam Cabello-Olmo; María Oneca; María José Pajares; Maddalen Jiménez; Josune Ayo; Ignacio J. Encío; Miguel Barajas; Miriam Araña
Source:
Nutrients 2022 v.14 no.3 pp. -
ISSN:
2072-6643
Subject:
Pediococcus acidilactici; animal models; blood glucose; body weight changes; c-peptide; disease progression; gene expression; glucagon-like peptide 1; glucose; glucose tolerance; glucose tolerance tests; high fat diet; histology; insulin resistance; interleukin-6; intestinal microorganisms; intestines; leptin; lipid composition; noninsulin-dependent diabetes mellitus; placebos; probiotics; risk factors; villi
Abstract:
... Prediabetes (PreD), which is associated with impaired glucose tolerance and fasting blood glucose, is a potential risk factor for type 2 diabetes mellitus (T2D). Growing evidence suggests the role of the gastrointestinal microbiota in both PreD and T2D, which opens the possibility for a novel nutritional approach, based on probiotics, for improving glucose regulation and delaying disease progressi ...
DOI:
10.3390/nu14030692

72. Antihyperglycemic Effects of Salvia polystachya Cav. and Its Terpenoids: α-Glucosidase and SGLT1 Inhibitors

Author:
Rocio Ortega; Miguel Valdés; Francisco J. Alarcón-Aguilar; Ángeles Fortis-Barrera; Elizabeth Barbosa; Claudia Velazquez; Fernando Calzada
Source:
Plants 2022 v.11 no.5 pp. -
ISSN:
2223-7747
Subject:
Salvia; absorption; acarbose; acute toxicity; computer simulation; drugs; ethyl acetate; galactose; glucose; glycemic effect; hydrolysis; hyperglycemia; intestines; oleanolic acid; starch; sucrose; ursolic acid
Abstract:
... The antihyperglycemic activity of ethanolic extract from Salvia polystachya (EESpS) and its products was evaluated using in vivo, ex vivo and in silico assays; additionally, an acute toxicity assay was evaluated. EESpS was classified as a nontoxic class 5 drug. EESpS, ethyl acetate fraction (EtOAcFr), secondary-6-fraction (SeFr6), ursolic acid (UA), and oleanolic acid (OA) reduced the hyperglycemi ...
DOI:
10.3390/plants11050575

73. Antimicrobial and antioxidant activity of proteins isolated from Melipona beecheii honey

Author:
Jesús M. Ramón-Sierra; Marco A. Villanueva; Alejandro Yam-Puc; Martha Rodríguez-Mendiola; Carlos Arias-Castro; Elizabeth Ortiz-Vázquez
Source:
Food chemistry: X 2022 v.13 pp. 100177
ISSN:
2590-1575
Subject:
Escherichia coli; Melipona beecheii; affinity chromatography; antibacterial properties; antioxidant activity; concanavalin A; food chemistry; free radical scavengers; glucose; honey
Abstract:
... Proteins from Melipona beecheii honey were purified by concanavalin A (conA) affinity chromatography and eluted with a stepwise glucose gradient into fractions named F2-F5. The conA-unbound fraction (F1) was further separated by molecular exclusion into fractions named MbF1-1,2 and MbF1-3. All fractions were evaluated for antibacterial activity against foodborne pathogens and antioxidant capacity. ...
DOI:
10.1016/j.fochx.2021.100177

74. Anti‐oxidant and anti‐fatigue properties of apple pomace polysaccharides by acid or alkali extraction

Author:
Xiangna Chang; Xuefeng Chen; Pin Gong; Wenjuan Yang; Lan Wang; Ning Liu; Yao Su; Yuanyuan Zhao
Source:
International journal of food science & technology 2022 v.57 no.1 pp. 78-91
ISSN:
0950-5423
Subject:
alkali treatment; apple pomace; apples; arabinose; food science; galactose; galacturonic acid; glucose; medicine; polysaccharides; rhamnose; structure-activity relationships; xylose
Abstract:
... The anti‐fatigue effects and structure‐activity relationship of apple polysaccharides (APPs), the active components in apple pomace, remain unknown. We examined the effects of different extraction methods on polysaccharide structures and anti‐fatigue activities. Additionally, the structural and biochemical properties of APPs prepared under acidic (ACAPP) or alkaline (ALAPP) conditions, were charac ...
DOI:
10.1111/ijfs.15200

75. Apios americana Medik flower extract protects high-glucose-treated hepatocytes and Caenorhabditis elegans

Author:
Su Zhou; Jiafei Chen; Fangyuan Fan; Yani Pan; Xinyu Feng; Lushuang Yu; Shuying Gong; Xiaodong Zheng; Yihong Jiang; Qiang Chu
Source:
Food bioscience 2022 v.45 pp. 101473
ISSN:
2212-4292
Subject:
Apios americana; Caenorhabditis elegans; flavonoids; flower extracts; glucose; hepatocytes; hyperglycemia; lipids; metabolism; noninsulin-dependent diabetes mellitus; oxidative stress; phosphorylation; North America
Abstract:
... Type 2 diabetes (T2D) is a chronic metabolic disease related to glucose metabolism disorders. Increasing evidences indicate that flavonoids obtained from plants have beneficial effects on T2D. Apios americana Medik, originally cultivated in North America, is rich in flavonoids. In this study, A. americana flower extract (AFE) was purified and flavonoids were identified. The beneficial effects of A ...
DOI:
10.1016/j.fbio.2021.101473

76. Apium graveolens reduced phytofabricated gold nanoparticles and their impacts on the glucose utilization pattern of the isolated rat hemidiaphragm

Author:
Rajasekar Panchamoorthy; Udayamathi Mohan; Anbarasan Muniyan
Source:
Heliyon 2022 v.8 no.1 pp. e08805
ISSN:
2405-8440
Subject:
Apium graveolens; bioactive properties; cell lines; cherries; color; computer simulation; diaphragm; flavonoids; glucose; insulin; nanogold; phytotherapy; polyphenols; rats; zeta potential
Abstract:
... The integration of nanotechnology with herbal medicines overcomes the limitations of herbal therapy and offers desirable bioactivity. Thus, this study was aimed at synthesizing Apium graveolens-gold nanoparticles (AG-AuNPs) and exploring their impact on the glucose utilization pattern of the isolated rat hemidiaphragm. The AG-AuNPs appeared in cherry red color and showed a plasmonic peak at 534nm. ...
DOI:
10.1016/j.heliyon.2022.e08805

77. Apple-based coatings incorporated with wild apple isolated yeast to reduce Penicillium expansum postharvest decay of apples

Author:
Laura Settier-Ramírez; Gracia López-Carballo; Pilar Hernández-Muñoz; Angélique Fontana-Tachon; Caroline Strub; Sabine Schorr-Galindo
Source:
Postharvest biology and technology 2022 v.185 pp. 111805
ISSN:
0925-5214
Subject:
Metschnikowia pulcherrima; Penicillium expansum; antifungal properties; apple pomace; apples; biological control; culture media; disease control; edible films; glucose; industry; liquids; methylcellulose; molds (fungi); patulin; pectins; postharvest diseases; technology; viability; yeast extract; yeasts
Abstract:
... The aim of this work has been to prevent the growth of Penicillium expansum on the surface of apples by means of the use of biocontrol agents in combination with edible coatings. For that, Metschnikowia pulcherrima yeast isolated from wild apples was incorporated in edible film matrices based on pectins, cellulose ethers with and without the addition of liquid culture medium (yeast extract and glu ...
DOI:
10.1016/j.postharvbio.2021.111805

78. Application of a statistical design to evaluate bioethanol production from Chlorella S4 biomass after acid - Thermal pretreatment

Author:
Mahroo Seyed Jafari Olia; Mehrdad Azin; Nasrin Moazami
Source:
Renewable energy 2022 v.182 pp. 60-68
ISSN:
0960-1481
Subject:
Chlorella; Saccharomyces cerevisiae; biomass; carbon; ethanol; ethanol production; fermentation; glucose; heat tolerance; hydrolysates; microalgae; renewable energy sources; specific growth rate; yeasts
Abstract:
... This research evaluates the potential of a native marine isolate, Chlorella S4, for bioethanol production using the Thermo-Tolerant (TT) strain of Saccharomyces cerevisiae. Initially, an acid-thermal pretreatment with different concentrations of microalgal biomass (2, 4, and 6% (w/v)) and H₂SO₄ (1.5, 3, and 4.5% (v/v)) was investigated to improve the release of glucose (an important substrate of f ...
DOI:
10.1016/j.renene.2021.10.019

79. Aqueous two-phase simultaneous extraction and purification of a polysaccharide from Grifola frondosa: Process optimization, structural characteristics and antioxidant activity

Author:
Guanghua Mao; Ping Yu; Ting Zhao; Yao Chen; Weiwei Feng; Qiaoyue Zhang; Liuqing Yang; Xiangyang Wu
Source:
Industrial crops and products 2022 v.184 pp. 114962
ISSN:
0926-6690
Subject:
Grifola frondosa; ammonium sulfate; antioxidant activity; antioxidants; chromatography; dose response; ethanol; glucose; microstructure; molecular weight; pH; polysaccharides; response surface methodology
Abstract:
... Traditional method for Grifola frondosa polysaccharide (CGFP) separation is water extraction or other method assistance, ethanol precipitation and further purification via column chromatography. Due to the strict control conditions, inefficient and not environmental-friendly, the method is hard to scale up and implement, and even limited the biological activity study and application of Grifola fro ...
DOI:
10.1016/j.indcrop.2022.114962

80. Are Peripheral Biomarkers Determinants of Eating Styles in Childhood and Adolescence Obesity? A Cross-Sectional Study

Author:
Lorena Desdentado; Jaime Navarrete; María Folgado-Alufre; Ana de Blas; Jéssica Navarro-Siurana; Francisco Ponce; Guadalupe Molinari; Andrea Jimeno-Martínez; Azahara I. Rupérez; Gloria Bueno-Lozano; Aida Cuenca-Royo; Emili Corbella; Zaida Agüera; Rosa M. Baños; Julio Álvarez-Pitti
Source:
Nutrients 2022 v.14 no.2 pp. -
ISSN:
2072-6643
Subject:
adiponectin; adolescence; biomarkers; childhood; childhood obesity; ghrelin; glucose; hematologic tests; insulin; insulin resistance; leptin; models; questionnaires; regression analysis; variance
Abstract:
... Disturbances in eating behaviors have been widely related to obesity. However, little is known about the role of obesity-related biomarkers in shaping habitual patterns of eating behaviors (i.e., eating styles) in childhood. The objective of the present study was to explore the relationships between several biomarkers crucially involved in obesity (ghrelin, insulin resistance, and leptin/adiponect ...
DOI:
10.3390/nu14020305

81. Assessment of metal exposure (uranium and copper) in fatty acids and carbohydrate profiles of Calamoceras marsupus larvae (Trichoptera) and Alnus glutinosa leaf litter

Author:
Marina Tagliaferro; Carolina Rocha; João C. Marques; Ana M.M. Gonçalves
Source:
Science of the total environment 2022 v.836 pp. 155613
ISSN:
0048-9697
Subject:
Alnus glutinosa; Trichoptera; arabinose; biofilm; copper; detritivores; environment; fucose; galactose; glucose; mannose; plant litter; polyunsaturated fatty acids; uranium
Abstract:
... Physiological changes were explored in fatty acids (FA) and carbohydrate (CHO) composition in the shredder Calamoceras marsupus larvae (Trichoptera) and leaf litter (C. marsupus food) exposed to copper and uranium under natural and experimental conditions. We measured FA and CHO content in leaf litter and larvae specimens from reference and impacted streams, and exposed for 5 weeks to four realist ...
DOI:
10.1016/j.scitotenv.2022.155613

82. Assessment of physiological barriers to nutrition following critical illness

Author:
James Whitehead; Matthew J. Summers; Rhea Louis; Luke M. Weinel; Kylie Lange; Bethany Dunn; Marianne J. Chapman; Lee-anne S. Chapple
Source:
Clinical nutrition 2022 v.41 no.1 pp. 11-20
ISSN:
0261-5614
Subject:
absorption; blood; clinical nutrition; glucose; intestines; liquids; metabolism; observational studies
Abstract:
... Nutrition may be important for recovery from critical illness. Gastrointestinal dysfunction is a key barrier to nutrition delivery in the Intensive Care Unit (ICU) and metabolic rate is elevated exacerbating nutritional deficits. Whether these factors persist following ICU discharge is unknown. We assessed whether delayed gastric emptying (GE) and impaired glucose absorption persist post-ICU disch ...
DOI:
10.1016/j.clnu.2021.11.001

83. Assessment of the effectiveness of a novel BioFilm-Membrane BioReactor oil-polluted wastewater treatment technology by applying biomarkers in the mussel Mytilus galloprovincialis

Author:
Ilaria Caliani; Giuseppe De Marco; Tiziana Cappello; Alessia Giannetto; Giuseppe Mancini; Stefania Ancora; Maria Maisano; Vincenzo Parrino; Simone Cappello; Nicola Bianchi; Sabrina Oliva; Antonella Luciano; Angela Mauceri; Claudio Leonzio; Salvatore Fasulo
Source:
Aquatic toxicology 2022 v.243 pp. 106059
ISSN:
0166-445X
Subject:
DNA damage; Mytilus galloprovincialis; biomarkers; bioreactors; energy metabolism; gene expression; genotoxicity; glucose; glycogen; health status; hypoxia; mussels; oils; oxygen; pollution; taurine; wastewater; wastewater treatment
Abstract:
... Petrochemical industries and oil refineries are sources of hazardous chemicals into the aquatic environments, and often a leading cause of reduced oxygen availability, thus resulting in adverse effects in biota. This study is an expansion of our previous work on the assessment of the BioFilm-Membrane Bioreactor (BF-MBR) to mitigate the impact of oil-polluted wastewater on marine environments. Spec ...
DOI:
10.1016/j.aquatox.2021.106059

84. Assessment of toxicity in the freshwater tadpole Polypedates maculatus exposed to silver and zinc oxide nanoparticles: A multi-biomarker approach

Author:
Meesala Krishna Murthy; Chandra Sekhar Mohanty; Priyabrata Swain; Rojalin Pattanayak
Source:
Chemosphere 2022 v.293 pp. 133511
ISSN:
0045-6535
Subject:
Polypedates; alanine transaminase; albumins; alkaline phosphatase; antioxidants; bioaccumulation; blood serum; cholesterol; cortisol; creatinine; freshwater; globulins; glucose; hematocrit; hemoglobin; kidneys; liver; lysozyme; monocytes; nanosilver; neutrophils; oxidative stress; protein content; silver; tadpoles; toxicity; urea; wastewater; zinc; zinc oxide
Abstract:
... Nanoparticles (NPs), especially silver nanoparticles (Ag NPs) and zinc oxide nanoparticles (ZnO NPs), are widely used in various industrial applications and are released into the surrounding environment through industrial and household wastewater. They have enormous toxic effects on aquatic animals and amphibians. In the current study, a multi-biomarker approach was used to assess toxicity on Poly ...
DOI:
10.1016/j.chemosphere.2021.133511

85. Associating diethylhexyl phthalate to gestational diabetes mellitus via adverse outcome pathways using a network-based approach

Author:
Tao Zhang; Shuo Wang; Ludi Li; An Zhu; Qi Wang
Source:
Science of the total environment 2022 v.824 pp. 153932
ISSN:
0048-9697
Subject:
adverse outcome pathways; data collection; endocrine-disrupting chemicals; environment; fetus; gene ontology; gestational diabetes; glucose; human health; phthalates; pregnancy; toxicogenomics; toxicology; women
Abstract:
... Gestational diabetes mellitus (GDM) is a common pregnancy complication that is harmful to both the woman and fetus. Several epidemiological studies have found that exposure to diethylhexyl phthalate (DEHP), an endocrine disruptor ubiquitous in the environment, may be associated with GDM. This study aims to investigate the mechanism between DEHP and GDM using the adverse outcome pathway (AOP) frame ...
DOI:
10.1016/j.scitotenv.2022.153932

86. Association between hepatic iron overload assessed by magnetic resonance imaging and glucose intolerance states in the general population

Author:
Muhammad Naeem; Sabine Schipf; Robin Bülow; Nicole Werner; Marcus Dörr; Markus M. Lerch; Jens-Peter Kühn; Wolfgang Rathmann; Matthias Nauck; Marcello Ricardo Paulista Markus; Giovanni Targher; Till Ittermann; Henry Völzke
Source:
Nutrition, metabolism, and cardiovascular diseases 2022 pp. -
ISSN:
0939-4753
Subject:
biomarkers; blood glucose; glucose; glucose tolerance; iron; iron overload; lipid content; magnetism; noninsulin-dependent diabetes mellitus; nutrition; regression analysis; relative risk
Abstract:
... While there is evidence that iron overload disorders are associated with type 2 diabetes, the relationship between hepatic iron overload and prediabetes remains unclear. We aimed to investigate the association between hepatic iron overload, as assessed by magnetic resonance imaging (MRI), and different glucose intolerance states in the population-based Study. We included data from 1622 individuals ...
DOI:
10.1016/j.numecd.2022.02.013

87. Association of fresh low-molecular-weight organic compounds with clay-sized mineral fraction in soils of different organic carbon loading

Author:
Tianyi Wu; Alexander D. Ost; Jean-Nicolas Audinot; Martin Wiesmeier; Tom Wirtz; Franz Buegger; Werner Häusler; Carmen Höschen; Carsten W. Mueller
Source:
Geoderma 2022 v.409 pp. 115657
ISSN:
0016-7061
Subject:
agricultural research; amino acids; clay; direct seeding; fallow; glucose; nitrogen content; organic carbon
Abstract:
... Although the association of minerals and organic matter (OM) in soil plays an important role in the sequestration of C, the factors driving the initial formation of mineral-associated OM (MAOM), and thus the retention of new C input in soils are not yet fully understood. In this study, we investigated how the soil C loading and the differences in the N content of low-molecular-weight organic compo ...
DOI:
10.1016/j.geoderma.2021.115657

88. Association of lower circulating Spexin levels with higher body mass indices and glucose metabolic profiles in adult subjects in Egypt

Author:
Eman Salah Albeltagy; Nashwa Mohamed Abd Elbaky
Source:
Human nutrition & metabolism 2022 v.27 pp. 200137
ISSN:
2666-1497
Subject:
adiposity; adults; biomarkers; blood glucose; blood serum; cross-sectional studies; diabetes; diet; fatty liver; glucose; health status; human nutrition; lipid composition; metabolism; mice; obesity; odds ratio; peptides; physical activity; regression analysis; Egypt
Abstract:
... Spexin (SPX) is a novel peptide hormone that lowers blood glucose levels and is protective against hepatic steatosis in diet induced obese mouse models. We hypothesized that higher circulating SPX levels would be associated with a lean BMI and a more favorable metabolic profile in humans. We aimed to investigate SPX levels and its association with obesity, glucose metabolic and cardiovascular fact ...
DOI:
10.1016/j.hnm.2021.200137

89. Associations between metabolic syndrome and anthropogenic heat emissions in northeastern China

Author:
Jianping Cong; Le-Bing Wang; Fang-Jie Liu; Zhengmin (Min) Qian; Stephen Edward McMillin; Michael G. Vaughn; Yimeng Song; Shasha Wang; ShanShan Chen; Shimin Xiong; Xubo Shen; Xiao Sun; Yuanzhong Zhou; Hung Chak Ho; Guang-Hui Dong
Source:
Environmental research 2022 v.204 pp. 111974
ISSN:
0013-9351
Subject:
climate; confidence interval; cross-sectional studies; data collection; diastolic blood pressure; dose response; energy; glucose; heart diseases; heat transfer; high density lipoprotein cholesterol; humans; metabolic syndrome; metabolism; normalized difference vegetation index; odds ratio; research; risk; satellites; socioeconomics; stroke; systolic blood pressure; temperature; transportation; waist circumference; China
Abstract:
... Recent research attention has been paid to anthropogenic heat emissions (AE), temperature increase generated by human activity such as lighting, transportation, manufacturing, construction, and building climate controls. However, there is no epidemiological data available to investigate the association between anthropogenic heat emissions and metabolic syndrome (MetS), a cluster of conditions that ...
DOI:
10.1016/j.envres.2021.111974

90. Associations of dietary glycemic index and load during pregnancy with blood pressure, placental hemodynamic parameters and the risk of gestational hypertensive disorders

Author:
Clarissa J. Wiertsema; Rama J. Wahab; Annemarie G. M. G. J. Mulders; Romy Gaillard
Source:
European journal of nutrition 2022 v.61 no.2 pp. 703-716
ISSN:
1436-6207
Subject:
diastolic blood pressure; glucose; glycemic index; glycemic load; lifestyle; metabolism; pregnancy; risk; ultrasonics
Abstract:
... PURPOSE: The aim of this study was to examine the associations of dietary glycemic index and load with gestational blood pressure, placental hemodynamic parameters and the risk of gestational hypertensive disorders. METHODS: In a population-based cohort among 3378 pregnant Dutch women, dietary glycemic index and load were assessed from food frequency questionnaires at median 13.4 (95% range 9.9–22 ...
DOI:
10.1007/s00394-021-02670-5

91. Associations of propylene oxide exposure with fasting plasma glucose and diabetes: Roles of oxidative DNA damage and lipid peroxidation

Author:
Wei Liu; Bin Wang; Shijie Yang; Tao Xu; Linling Yu; Xing Wang; Man Cheng; Min Zhou; Weihong Chen
Source:
Environmental pollution 2022 v.292 pp. 118453
ISSN:
0269-7491
Subject:
DNA; DNA damage; biomarkers; blood glucose; diabetes; glucose; hyperglycemia; lipid peroxidation; metabolism; metabolites; oxidative stress; pollution; propylene oxide; risk; urine
Abstract:
... Whether propylene oxide (PO) exposure is associated with hyperglycemia were rarely explored. We aimed to determine the relationship between PO exposure and glucose metabolism, and potential role of oxidative stress. Among 3294 Chinese urban adults, urinary PO metabolite (N-Acetyl-S-(2-hydroxypropyl)-L-cysteine, 2HPMA), biomarkers of oxidative DNA damage (8-oxo-7,8-dihydro-20-deoxyguanosine, 8-OHdG ...
DOI:
10.1016/j.envpol.2021.118453

92. Autocatalytic oncotherapy nanosystem with glucose depletion for the cascade amplification of hypoxia-activated chemotherapy and H₂O₂-dependent chemodynamic therapy

Author:
Yao Hu; Song Bai; Xingyu Fan; Fangfang Zhou; Botao Chen; Songwen Tan; Hui Xu; Anqiang Pan; Shuquan Liang; Yongju He
Source:
Biomaterials science 2022 v.10 no.9 pp. 2358-2369
ISSN:
2047-4849
Subject:
biocompatible materials; drug therapy; glucose; glucose oxidase; glutathione; hypoxia; neoplasms; porous media; silica; starvation; toxicity
Abstract:
... Employing hypoxia-activated prodrugs is an appealing oncotherapy strategy, but limited by insufficient tumor hypoxia. Moreover, a standalone prodrug fails to treat tumors satisfactorily due to tumor complexity. Herein, a nanosystem (TPZ@FeMSN-GOX) was established for triple synergetic cancer starvation therapy, hypoxia-activated chemotherapy and chemodynamic therapy (CDT). TPZ@FeMSN-GOX was prepar ...
DOI:
10.1039/d1bm01944a

93. Autophagy protects against high uric acid-induced hepatic insulin resistance

Author:
Furong He; Mei Wang; Hairong Zhao; De Xie; Jiaming Lv; Weidong Liu; Wei Yu; Qiang Wang; Binyang Chen; Chenxi Xu; Tetsuya Yamamoto; Hidenori Koyama; Jidong Cheng
Source:
Molecular and cellular endocrinology 2022 v.547 pp. 111599
ISSN:
0303-7207
Subject:
acetylcysteine; adenine; autophagy; blood glucose; glucose; homeostasis; insulin; insulin resistance; metabolism; phosphorylation; protective effect; rapamycin; reactive oxygen species; therapeutics; uric acid
Abstract:
... Uric acid (UA), the end-product of purine metabolism, is closely related to hepatic insulin resistance (IR). Autophagy is a conserved intracellular degradation process maintaining cellular homeostasis. Autophagy plays a protective role in obesity-related hepatic IR, but whether it occurs in high uric acid (HUA)-induced hepatic IR is unclear. In this study, spontaneously elevated UA level induced h ...
DOI:
10.1016/j.mce.2022.111599

94. Bacillus velezensis SX13 promoted cucumber growth and production by accelerating the absorption of nutrients and increasing plant photosynthetic metabolism

Author:
Junzheng Wang; Feng Qu; Jiayi Liang; Mingfei Yang; Xiaohui Hu
Source:
Scientia horticulturae 2022 v.301 pp. 111151
ISSN:
0304-4238
Subject:
Bacillus velezensis; absorption; biomass production; carbon metabolism; cucumbers; dose response; fructose; fructose-bisphosphate aldolase; fruit quality; glucose; glutamate dehydrogenase; glutamine; nitrate reductase; nitrogen metabolism; organic phosphorus; phosphoenolpyruvate carboxylase; photosynthesis; plant growth-promoting rhizobacteria; rhizosphere; seedling growth; sucrose; sucrose-phosphate synthase
Abstract:
... Rhizosphere colonization by plant growth-promoting rhizobacteria (PGPR) facilitates the ability of PGPR to promotes plant growth and health. Among the rhizosphere microbial communities, the dominant PGPR strains should be tapped to analyze their growth-promoting mechanism, and then promote the development and utilization of related agricultural products. In the current study, Bacillus velezensis S ...
DOI:
10.1016/j.scienta.2022.111151

95. Behavioral and metabolic responses of ponies fed a complete single diet, thermally processed and containing long fiber

Author:
Kátia Feltre; Júlio César de Carvalho Balieiro; Alexandre Augusto de Oliveira Gobesso
Source:
Livestock science 2022 v.258 pp. 104878
ISSN:
1871-1413
Subject:
Cenchrus purpureus; Zea mays; cholesterol; diet; glucose; grasses; hay; horses; insulin; metabolism; nutrient utilization; pellets
Abstract:
... Alternatives horse's feed are ways to improve nutrient utilization as well as reduce production costs. The objective of this research was to describe behavioral and metabolic changes in ponies fed with complete diets composed of different grasses as fiber sources and industrial processing (thermal). Eight ponies were randomized into two Latin squares. The treatments were: ‘control diet’ (tradition ...
DOI:
10.1016/j.livsci.2022.104878

96. Beneficial effects of Ilex paraguariensis in the prevention of obesity‐associated metabolic disorders in mice

Author:
Helber da Maia Valença; Cyntia Pecli e Silva; Lycia de Brito Gitirana; Samuel Santos Valença; Manuella Lanzetti
Source:
Phytotherapy research 2022 v.36 no.2 pp. 1032-1042
ISSN:
0951-418X
Subject:
Ilex paraguariensis; adipocytes; adipose tissue; antioxidant activity; biomarkers; blood; dimethyl fumarate; fatty liver; glucose; heme oxygenase (biliverdin-producing); high density lipoprotein; high fat diet; histology; hypertrophy; inflammation; leptin; liver; obesity; oxidative stress; phytotherapy; quinones; research; resistin; superoxide dismutase
Abstract:
... Obesity is a chronic condition involving inflammation and oxidative stress that commonly predisposes affected individuals to develop metabolic disorders. We hypothesize that Ilex paraguariensis (IP) can modulate oxidative stress and inflammation underpinning metabolic disorders caused by obesity. C57BL/6 mice were fed a high‐fat diet (HFD group) for 12 weeks. Concomitantly, some mice were treated ...
DOI:
10.1002/ptr.7377

97. Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia muciniphila

Author:
Anandita Pal; Shan Sun; Michael Armstrong; Jonathan Manke; Nicole Reisdorph; Victoria R. Adams; Arion Kennedy; Yujiao Zu; Naima Moustaid-Moussa; Ian Carroll; Saame Raza Shaikh
Source:
Biochimica et biophysica acta 2022 v.1867 no.1 pp. 159059
ISSN:
1388-1981
Subject:
RNA; biosynthesis; cell culture; cell differentiation; eicosapentaenoic acid; females; genes; glucose; high fat diet; homeostasis; insulin; intestinal microorganisms; intestines; males; mass spectrometry; mice; risk
Abstract:
... Eicosapentaenoic acid (EPA) ethyl esters are of interest given their clinical approval for lowering circulating triglycerides and cardiometabolic disease risk. EPA ethyl esters prevent metabolic complications driven by a high fat diet in male mice; however, their impact on female mice is less studied. Herein, we first investigated how EPA influences the metabolic profile of female C57BL/6J mice co ...
DOI:
10.1016/j.bbalip.2021.159059

98. Bi-directional feedback controlled transience in Cucurbituril based tandem nanozyme

Author:
Saurav Das; Priyam Das; Payel Dowari; Basab Kanti Das; Debapratim Das
Source:
Journal of colloid and interface science 2022 v.614 pp. 172-180
ISSN:
0021-9797
Subject:
catalytic activity; gluconic acid; gluconolactone; glucose; glucose oxidase; histidine; imines; lipid bilayers; oxidation; pH; peptides; peroxidase; substrate specificity; surfactants
Abstract:
... Life is fueled by multi-enzymatic tandem processes that display unmatched catalytic efficiencies owing to certain features of the biological reactors such as compartmentalization, nano-confinement, and out-of-equilibrium dynamics. With an attempt to match such natural catalytic systems, herein, we present a chemoenzymatic pH clock mediated transient assembly of a vesicular nanozyme. Distinct confi ...
DOI:
10.1016/j.jcis.2022.01.092

99. Bimetallic Layered Hydroxide Nitrate@Graphene Oxide as an Electrocatalyst for Efficient Non-Enzymatic Glucose Sensors: Tuning Sensitivity by Hydroxide-Regulated M₂(OH)₄–ₙ(Aⁿ–) Phases Derived from Solvent Engineering

Author:
Sampath Gayathri; Paulraj Arunkumar; Jaekook Kim; Jong Hun Han
Source:
ACS sustainable chemistry & engineering 2022 v.10 no.4 pp. 1689-1701
ISSN:
2168-0485
Subject:
carbonates; catalysts; catalytic activity; detection limit; electrochemistry; ethanol; glucose; graphene oxide; green chemistry; nanosheets; nitrates; oxidation; solvents; synergism
Abstract:
... Owing to their high catalytic activity, transition metal hydroxides are promising electrocatalysts for non-enzymatic glucose sensors. The hydroxyl functionalities in Co₁–ₓNiₓ hydroxide/mixed anionic hydroxides play a vital role in their electrochemical activation via conversion to an oxyhydroxide catalyst and thus impact their sensitivity to small molecule (glucose) oxidation. Herein, we report th ...
DOI:
10.1021/acssuschemeng.1c07644

100. Bioactive and technological properties of an α-D-glucan synthesized by Weissella cibaria PDER21

Author:
Mustafa Tahsin Yilmaz; Humeyra Ispirli; Osman Taylan; Mohammed Alamoudi; Enes Dertli
Source:
Carbohydrate polymers 2022 v.285 pp. 119227
ISSN:
0144-8617
Subject:
Weissella cibaria; antioxidant activity; antioxidants; food industry; glucans; glucose; thermal stability; water holding capacity; water solubility
Abstract:
... A slimy-mucinous-type colony of EPS-producing Weissella cibaria PDER21 was isolated and identified. The monomer composition was glucose, showing that the EPS is a glucan type homopolysaccharide, The core structure of (1 → 6)-linked α-d-glucose units including (1 → 3)-linked α-d-glucose branches at a ratio of 93.4/6.6 was revealed by ¹H and ¹³C NMR spectra and confirmed by FTIR analysis. The glucan ...
DOI:
10.1016/j.carbpol.2022.119227