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- Author:
- Xia, Hong, et al. ; Liu, Zhaoxiang; Zhang, Hua; Wang, Baocheng; Zhang, Renwen; Zeng, Qun; Guo, Lingzhi; Shen, Kui; Wang, BaTa; Zhong, Yanheng; Li, Zhizhong; Sun, Guodong; Show all 12 Authors
- Source:
- Biochemical and biophysical research communications 2019 v.512 no.2 pp. 367-372
- ISSN:
- 0006-291X
- Subject:
- CD8-positive T-lymphocytes; animal injuries; animal models; biotin; cerebrospinal fluid; cytokines; enzyme-linked immunosorbent assay; flow cytometry; humans; infectious diseases; inflammation; mice; permeability; spinal cord; staining
- Abstract:
- ... Perforin plays an important role in autoimmune and infectious diseases, but its function in immune inflammatory responses after spinal cord injury (SCI) has received insufficient attention. The goal of this study is to determine the influence of perforin after spinal cord injury (SCI) on secondary inflammation. Compared recovery from SCI in perforin knockout (Prf1−/−) and wild-type(WT)mice, WT mic ...
- DOI:
- 10.1016/j.bbrc.2019.03.002
- https://dx.doi.org/10.1016/j.bbrc.2019.03.002
- Author:
- Xia, Hong-Fei, et al. ; Wang, Rui; Sun, Da-Guang; Song, Ge; Guan, Chun Yi; Cui, Yi; Ma, Xu; Show all 7 Authors
- Source:
- Environmental science and pollution research international 2019 v.26 no.29 pp. 29763-29779
- ISSN:
- 0944-1344
- Subject:
- abnormal development; amniotic fluid; animal experimentation; apoptosis; chick embryos; chickens; choline; dibutyl phthalate; embryogenesis; enzyme-linked immunosorbent assay; folic acid; gas chromatography-mass spectrometry; humans; malondialdehyde; metabolites; neural tube defects; oxidation; oxidative stress; pollutants; reactive oxygen species; superoxide dismutase; teratogenicity; urine
- Abstract:
- ... Dibutyl phthalate (DBP), a persistent environmental pollutant, can induce neural tube abnormal development in animals. The possible effects of DBP exposure on human neural tube defects (NTDs) remain elusive. In this study, the distribution of DBP in the body fluid of human NTDs was detected by GC-MS. Then, chick embryos were used to investigate the effects of DBP on early embryonic development. Ox ...
- DOI:
- 10.1007/s11356-019-06087-w
- https://dx.doi.org/10.1007/s11356-019-06087-w
- Author:
- Xia, Hong, et al. ; Wang, Gong; Zhang, Yang; Yang, Han; Wang, Wei; Dai, Yun-Zhi; Niu, Li-Gang; Lv, Chao; Liu, Tao; Show all 9 Authors
- Source:
- RSC advances 2020 v.10 no.15 pp. 8910-8916
- ISSN:
- 2046-2069
- Subject:
- drug injection; equipment; human health; humans; humidity; manufacturing; monitoring; pharmacology; physiology; rats
- Abstract:
- ... Respiration monitoring equipment has wide applications in daily health monitoring and modern medical diagnosis. Despite significant progress being made in humidity sensors for respiration monitoring, the fabrication of the humidity sensors with low-cost, simple manufacturing process and easy integration remains a challenge. This work reports a facile and inexpensive laser printing fabrication of P ...
- DOI:
- 10.1039/c9ra10409g
- http://dx.doi.org/10.1039/c9ra10409g
- Author:
- Xia, Hong, et al. ; Fan, Xian-guang; Wu, Yi; Zhi, Yu-Liang; Wang, Xin; Show all 5 Authors
- Source:
- Micron 2020 v.130 pp. 102798
- ISSN:
- 0968-4328
- Subject:
- algorithms; equipment design; humans; scanning tunneling microscopy
- Abstract:
- ... The Scanning tunneling microscope (STM) is a micro instrument designed for surface morphology with nanometer precision. The restoration of the STM image defects usually needs human judgements and manual positioning because of the diversity of the morphology and the randomness of the defects. This paper provides a new fully-automatic method that combines deep convolutional neural classification net ...
- DOI:
- 10.1016/j.micron.2019.102798
- https://dx.doi.org/10.1016/j.micron.2019.102798
- Author:
- Xia, Hong-Xing, et al. ; Wen, Wei; Huang, Jing-Yi; Bao, Ting; Zhou, Jun; Zhang, Xiu-Hua; Wang, Sheng-Fu; Zhao, Yuan-Di; Show all 8 Authors
- Source:
- Biosensors & bioelectronics 2016 v.83 pp. 142-148
- ISSN:
- 0956-5663
- Subject:
- DNA; antigens; biomarkers; biosensors; biotin; blood serum; chemiluminescence immunoassays; detection limit; electrochemistry; electrodes; gold; graphene; humans; hydrogen; nanorods; neoplasms; oligonucleotides; oxidation; patients; peroxidase; respiratory tract diseases; single nucleotide polymorphism; streptavidin; thiols
- Abstract:
- ... We report a triplex signal amplification strategy for sensitive biosensing of cancer biomarker by taking advantage of hairpin-shaped oligonucleotide-functionalized gold nanorods (HO-GNRs), graphene and the avidin-biotin reation. The strategy expands electrochemical detection of carcinoembryonic antigen (CEA) by using an aptamer as biosensor's recognition element and HO-GNRs as signal enhancer. To ...
- DOI:
- 10.1016/j.bios.2016.04.039
- https://dx.doi.org/10.1016/j.bios.2016.04.039
- Author:
- Xia, Hong-Fei, et al. ; Tian, Shi; Su, Xing; Qi, Lu; Jin, Xiao-Hua; Hu, Yi; Wang, Chun-Ling; Ma, Xu; Show all 8 Authors
- Source:
- BBA - General Subjects 2015 v.1850 pp. 708-721
- ISSN:
- 0304-4165
- Subject:
- Northern blotting; Western blotting; bioinformatics; cell proliferation; embryo implantation; endometrium; epithelium; humans; immunohistochemistry; leukemia inhibitory factor; luciferase; pregnancy; pseudopregnancy; rats; stromal cells
- Abstract:
- ... To study the role of miR-143 during embryo implantation in rat.MiR-143 expression in rat early pregnancy was detected by Northern blot. The relation between miR-143 and Lifr predicted and confirmed by bioinformatics method, dual-luciferase activity assay, Western blot and immunohistochemistry. The role of miR-143 was detected by MTS, Edu and ranswell chamber assays.The expression level of miR-143 ...
- DOI:
- 10.1016/j.bbagen.2014.11.023
- http://dx.doi.org/10.1016/j.bbagen.2014.11.023
- Author:
- Xia, Hong-Fei, et al. ; Wang, Rui; Tian, Shi; Wang, Hong-Bin; Chu, Da-Peng; Cao, Jing-Li; Ma, Xu; Show all 7 Authors
- Source:
- FEBS letters 2014 v.588 pp. 4438-4447
- ISSN:
- 0014-5793
- Subject:
- breast neoplasms; carcinogenesis; cell proliferation; humans; tissues; vascular endothelial growth factors
- Abstract:
- ... MiR-185 expression has been associated with many cancers. However, the roles of miR-185 in human breast cancer remain elusive. Here, we found that miR-185 expression was decreased in human breast cancer tissues compared with healthy tissue controls. Up-regulation of miR-185 inhibited breast cancer cell proliferation and invasion and vice versa. MiR-185 was shown to bind to the 3′-untranslated regi ...
- DOI:
- 10.1016/j.febslet.2014.09.045
- http://dx.doi.org/10.1016/j.febslet.2014.09.045
- Author:
- Wang, Xia-hong, et al. ; Sun, Xiang-Yu; Zhao, Ping; Jin, Shu-fang; Liu, Min-Chao; Huang, Yu-min; Cheng, Zhen-feng; Yan, Si-Qi; Li, Yan-Yu; Chen, Ya-Qing; Zhong, Yan-Mei; Show all 11 Authors
- Source:
- Journal of photochemistry and photobiology 2017 v.173 pp. 606-617
- ISSN:
- 1011-1344
- Subject:
- DNA; antineoplastic agents; apoptosis; carbon; humans; ligands; mitochondria; molecular models; neoplasms; porphyrins; telomeres
- Abstract:
- ... DNA polymorphism exerts a fascination on a large scientific community. Without crystallographic structural data, clarification of the binding modes between G-quadruplex (G4) and ligand (complex) is a challenging job. In the present work, three porphyrin compounds with different flexible carbon chains (arms) were designed, synthesized and characterized. Their binding, folding and stabilizing abilit ...
- DOI:
- 10.1016/j.jphotobiol.2017.06.036
- https://dx.doi.org/10.1016/j.jphotobiol.2017.06.036