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- Srivastava, Kumkum, et al. Show all 8 Authors
- Biochemistry 2017 v.56 no.51 pp. 6691-6699
- DNA damage; Plasmodium falciparum; Protozoa; antigenic variation; antimalarials; chromatin; death; genes; homeostasis; humans; immune evasion; ligands; malaria; parasites; pathogenesis; pyridines; telomeres; toxicity; toxicity testing; transcription (genetics)
- ... The unique occurrence of G-quadruplexes in the AT-rich genome of human malaria parasite Plasmodium falciparum provides hints about their critical roles in parasite survival, pathogenesis, and host immune evasion. An intriguing question is whether these noncanonical structures can serve as molecular targets for small molecule-based interventions against malaria. In this study, we have investigated ...
- Srivastava, Kumkum, et al. Show all 4 Authors
- Research in microbiology 2013 v.164 no.3 pp. 211-215
- Mycoplasma orale; Plasmodium falciparum; blood groups; blood serum; erythrocytes; gentamicin; humans; in vitro culture; polymerase chain reaction
- ... The presence of foreign contamination, especially of mycoplasmas, is a major hindrance in long term in vitro cultivation of Plasmodium falciparum and may be a source of false-positive results. Efforts have been made to control mycoplasma contamination by trypsinization of P. falciparum culture. Samples of accidentally contaminated cultures were used for this study. The presence of Mycoplasma orale ...