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- Zhelifonova, V. P., et al. Show all 3 Authors
- Applied biochemistry and microbiology 2008 v.44 no.6 pp. 608-612
- Penicillium; biosynthesis; conidia; culture media; fungi; glucose; inhibitory concentration 50; ions; iron; mannitol; prostatic neoplasms; secondary metabolites; zinc
- ... Piscarinines A and B were synthesized most actively during the surface cultivation of the fungus Penicillium piscarium in a complex medium (5.5 mg/l). Under conditions of submerged cultivation in a mineral medium, the yield of piscarinines was two times lower. An increase in the inoculum quantity of conidia treated with Tween-80 increased the culture productivity. The biosynthesis of the alkaloid ...
- Zhelifonova, V. P., et al. Show all 4 Authors
- Applied biochemistry and microbiology 2010 v.46 no.5 pp. 525-529
- Penicillium citrinum; additives; biosynthesis; carbon; copper; enzymes; ergot alkaloids; fungi; growth retardation; ions; iron; mannitol; microbial growth; nitrogen; physiological state; quinoline alkaloids; secondary metabolites; sucrose; urea; zinc
- ... The fungus P. citrinum produces secondary metabolites, clavinet ergot alkaloids (EA), and quinoline alkaloids (quinocitrinines, QA) in medium with various carbon and nitrogen sources and in the presence of iron, copper, and zinc additives. Mannitol and sucrose are most favorable for EA biosynthesis and mannitol is most favorable for QA. Maximum alkaloid production is observed on urea. Iron and cop ...