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1. A comprehensive review of ethnopharmacology, phytochemistry, pharmacology, and pharmacokinetics of Schisandra chinensis (Turcz.) Baill. and Schisandra sphenanthera Rehd. et Wils.

Author:
Ke Yang; Jing Qiu; Zecheng Huang; Ziwei Yu; Wenjun Wang; Huiling Hu; Yu You
Source:
Journal of ethnopharmacology 2022 v.284 pp. 114759
ISSN:
0378-8741
Subject:
Japan; Magnoliaceae; Oriental traditional medicine; P-glycoproteins; Russia; Schisandra chinensis; cardioprotective effect; ethnobotany; flavonoids; glycemic effect; hepatoprotective effect; ingredients; lignans; neuroprotective effect; pharmacokinetics; phenolic acids; phytosterols; quality control; sleep disorders; therapeutics; toxicology; triterpenoids
Abstract:
... Schisandra chinensis (called bei-wuweizi in Chinese, S. chinensis) and Schisandra sphenanthera (called nan-wuweizi in Chinese, S. sphenanthera) are two highly similar plants in the Magnoliaceae family. Their dried ripe fruits are commonly used as traditional Chinese medicine in the treatment of coughs, palpitation, spermatorrhea, and insomnia. They also are traditionally used as tonics in Russia, ...
DOI:
10.1016/j.jep.2021.114759

2. A potential lignan botanical insecticide from Phryma leptostachya against Aedes aegypti: laboratory selection, metabolic mechanism, and resistance risk assessment

Author:
Xingtao Qie; Anqi Sun; Huanhuan Hao; Bo Lv; Wenjun Wu; Zhaonong Hu
Source:
Journal of pest science 2022 v.95 no.1 pp. 397-408
ISSN:
1612-4758
Subject:
Aedes aegypti; Phryma; botanical insecticides; chlorpyrifos; cross resistance; heritability; imidacloprid; instars; lignans; mosquito control; pests; resistance management; risk assessment
Abstract:
... The development of resistance to mosquitocides highlights the need for new insecticides that can be incorporated into a rational resistance management strategy. Botanical insecticides that are highly effective and safe to non-target organisms have recently gained attention. Haedoxan A (HA) is a lignan isolated from Phryma leptostachya L. that exhibits high activity against mosquito larvae. In the ...
DOI:
10.1007/s10340-021-01389-w

3. Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation

Author:
Jun Yamada; Shoichiro Maeda; Mariko Soya; Hidefumi Nishida; Kyoko M. Iinuma; Shozo Jinno
Source:
Journal of nutritional biochemistry 2022 pp. 109093
ISSN:
0955-2863
Subject:
Wisteria floribunda; adults; agglutinins; biosynthesis; chondroitin sulfate; cognition; estrogens; extracellular matrix; hippocampus; lignans; lipopolysaccharides; locomotion; memory; mice; neurogenesis; proteoglycans
Abstract:
... Lignans are plant-derived compounds that act as partial estrogen agonists. Chondroitin sulfate proteoglycans (CSPGs) represent one of the major components of the extracellular matrix (ECM). Here we aimed to understand the role of sesamin (SES), a major lignan compound, in the biosynthesis and degradation of CSPGs in the mouse hippocampus because CSPGs play a key role in the regulation of cognitive ...
DOI:
10.1016/j.jnutbio.2022.109093

4. Anti-inflammatory and cytotoxic specialised metabolites from the leaves of Glandularia × hybrida

Author:
Nesma M. Mohamed; Mai A.M. Ahmed; Shabana I. Khan; Frank R. Fronczek; Anber F. Mohammed; Samir A. Ross
Source:
Phytochemistry 2022 v.195 pp. 113054
ISSN:
0031-9422
Subject:
Glandularia; computer simulation; cytotoxicity; lignans; metabolites; pharmacokinetics; phytochemicals; triterpenoid saponins
Abstract:
... In our ongoing effort to investigate active specialised metabolites from genus Glandularia, phytochemical studies on the ethanolic extract of Glandularia × hybrida (Groenl. & Rümpler) G.L. Nesom & Pruski leaves resulted in the isolation of three undescribed compounds, a dibenzylbutyrolactolic lignan and two echinocystic acid based triterpenoid saponins, in addition to two known compounds. Interest ...
DOI:
10.1016/j.phytochem.2021.113054

5. Antiviral and Antioxidant Components from the Fruits of Illicium verum Hook.f. (Chinese Star Anise)

Author:
Wen Li; Zhongnan Wu; Yiping Xia; Jinlin Tan; Haiyue Zhao; Si Chen; Yaolan Li; Hongfeng Tang; Guocai Wang; Yubo Zhang
Source:
Journal of agricultural and food chemistry 2022 v.70 no.12 pp. 3697-3707
ISSN:
1520-5118
Subject:
Illicium verum; Orthomyxoviridae; anise; antioxidants; antiviral properties; circular dichroism spectroscopy; cuisine; cytopathogenicity; electrospray ionization mass spectrometry; fluorescent antibody technique; food chemistry; fruits; lignans; oseltamivir; phenylpropanoids; phytochemicals; spectral analysis; South East Asia
Abstract:
... Illicium verum Hook.f. (Chinese star anise), a known Chinese traditional spice, is commonly applied in Chinese cuisine and cooking in Southeast Asia. As a kind of medicinal and edible resource, the fruit of I. verum has attracted great attention for its chemical constituents and physiological activities. In this work, the phytochemical study of the fruits of I. verum led to the isolation and ident ...
DOI:
10.1021/acs.jafc.1c08376

6. Characterization of chemical constituents in Shuanghuanglian oral dosage forms by ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry

Author:
Ruiyun Li; Yanru Zhu; Mingyan Ma; Min Lei; Yingchun Zhao; Ting Liu; Miao Yu; Yunli Zhao; Zhiguo Yu
Source:
Journal of separation science 2022 v.45 no.5 pp. 1020-1030
ISSN:
1615-9306
Subject:
Oriental traditional medicine; anthraquinones; caffeic acid; coumarins; flavonoids; iridoids; lignans; mass spectrometry; oral administration; separation; triterpenoids; ultra-performance liquid chromatography
Abstract:
... Shuanghuanglian is a common traditional Chinese medicine prescription. It is an herbal formula composed of Lonicerae Japonicae Flos, Scutellariae Radix, and Forsythiae Fructus. A comprehensive understanding of Shuanghuanglian oral dosage forms components was obtained using a method based on ultra‐high performance liquid chromatography coupled with time‐of‐flight mass spectrometry for the separatio ...
DOI:
10.1002/jssc.202100860

7. Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica

Author:
Chia-Lin Lee; Yun-Lian Jhan; Hsiu-Mei Chiang; Yi-Hung Chen; Chao-Jung Chen; Yuan-Shiun Chang
Source:
Natural product research 2022 v.36 no.12 pp. 3133-3137
ISSN:
1478-6427
Subject:
Ampelopsis; anthraquinones; cosmetics; free radicals; glycosylation; keratinocytes; lignans; melanin; melanoma; research; stilbenes
Abstract:
... Three glycosylated stilbenes (1–3), two anthraquinones (4, 5), one lignan (6), five tannins (7–11), two amino acids (12, 13), and one auronol (14) were isolated from the root of Ampelopsis japonica. All compounds, except for 4, 6, and 11 were obtained from this species for the first time. Compounds 6–9 could notably inhibit ROS generations in HaCaT keratinocyte cells with IC₅₀ values of 5.28, 4.83 ...
DOI:
10.1080/14786419.2021.1939335

8. Characterization, expression, and functional analysis of the pathogenesis-related gene PtDIR11 in transgenic poplar

Author:
Lingling Li; Weibo Sun; Pu Wang; Hongyan Li; Shamsur Rehman; Dawei Li; Qiang Zhuge
Source:
International journal of biological macromolecules 2022 v.210 pp. 182-195
ISSN:
0141-8130
Subject:
Populus trichocarpa; biosynthesis; cell membranes; coniferyl alcohol; disease resistance; ethylene; flavonoids; genes; immunity; jasmonic acid; lignans; lignin; lignin content; methanol; pathogenesis-related proteins; quantitative polymerase chain reaction; reverse transcription; salicylic acid; signal transduction
Abstract:
... Lignins and lignans are important for plant resistance to pathogens. Dirigent (DIR) proteins control the regio- and stereo-selectivity of coniferyl alcohol in lignan and lignin biosynthesis. DIR genes have been implicated in defense-related responses in several plant species, but their role in poplar immunity is unclear. We cloned PtDIR11 from Populus trichocarpa; we found that overexpression of P ...
DOI:
10.1016/j.ijbiomac.2022.05.012

9. Chemical and biological studies of Daphniphyllum oldhamii from Hunan Province, China

Author:
Yi Chen; Shou-Mao Shen; Min Yang; Ming-Zhi Su; Xiao-Ming Wang; Yue-Wei Guo
Source:
Phytochemistry 2022 v.199 pp. 113170
ISSN:
0031-9422
Subject:
Daphniphyllum; X-ray diffraction; lignans; plant biochemistry; spectral analysis; triterpenoids; China
Abstract:
... The fruits, twigs and leaves of Daphniphyllum oldhamii (Hemsl.) K. Rosenthal, collected from Longshan County, Hunan Province, China, were chemically investigated. Three undescribed daphniphyllum alkaloids, namely longshanoldhamines A‒C, and six known related ones have been isolated from the fruits, whereas two undescribed triterpenoids and one undescribed lignan, along with six known triterpenoids ...
DOI:
10.1016/j.phytochem.2022.113170

10. Chemical constituents and their antioxidant and anti-inflammatory activities from edible Cornus officinalis fruits

Author:
Zhongcan Peng; Yuming Wang; Jun He; Jia Zhang; Xuege Pan; Xiansheng Ye; Weiku Zhang; Jiekun Xu
Source:
European food research & technology 2022 v.248 no.4 pp. 1003-1010
ISSN:
1438-2377
Subject:
2,2-diphenyl-1-picrylhydrazyl; Cornus officinalis; acid hydrolysis; cell lines; electrospray ionization mass spectrometry; food production; food research; functional foods; inflammation; interleukin-6; lignans; lipopolysaccharides; macrophages; nitric oxide; phytochemicals; technology; traditional medicine
Abstract:
... Cornus officinalis fruits, an edible functional food with the tonic effect, belongs to the Cornaceae family. It is widely used in both traditional medicine and in some food production. A phytochemical study on the fruits of Cornus officinalis resulted in 20 structurally diverse compounds including 2 new lignans, named officinalignans A-B (1–2), and 2 new iridoids, named loganin-(4′-O-7″)-α-morroni ...
DOI:
10.1007/s00217-021-03940-6

11. Chemical constituents from Dracocephalum moldavica L. and their chemotaxonomic significance

Author:
Jiaming Wang; Jinfeng Sun; Mengjie Wang; Huiqiong Cui; Wei Zhou; Gao Li
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104422
ISSN:
0305-1978
Subject:
Dracocephalum moldavica; chemotaxonomy; ecology; glycosides; lignans; monoterpenoids; norisoprenoids; phytochemicals; spectral analysis; triterpenoids
Abstract:
... A phytochemical investigation of the aerial parts of Dracocephalum moldavica L. (Lamiaceae) led to the isolation and characterization of 30 compounds, including eight lignans (1–8), seven phenols (9–15), five triterpenoids (16–20), four monoterpenoids (21–24), four glycosides (25–28) and two megastigmanes (29 and 30). The structures of these compounds were determined by spectroscopic data analysis ...
DOI:
10.1016/j.bse.2022.104422

12. Chemical constituents from Salvinia natans (L.) All. (Salviniaceae) and their chemotaxonomic significance

Author:
Hien Giang Pham; Manh Tuan Ha; Thao Quyen Cao; Ngoc Khanh Vu; Thi Thanh Le; Byung Sun Min
Source:
Biochemical systematics and ecology 2022 v.102 pp. 104410
ISSN:
0305-1978
Subject:
Salvinia natans; chemotaxonomy; ecology; lignans; norisoprenoids; phenanthrenes; phytochemicals; spectral analysis
Abstract:
... The phytochemical research on Salvinia natans (L.) All. resulted in the isolation of 11 compounds, subdivided into four steroids (1–4), three megastigmanes (5–7), two lignans (8 and 9), one phenanthrene (10), and one nepetolactone derivative (11). The structures of these compounds were elucidated mainly by NMR spectroscopic analysis and comparison with the published data. All these compounds were ...
DOI:
10.1016/j.bse.2022.104410

13. Chemical constituents from the roots of Actinidia valvata Dunn

Author:
Changwei Song; Chunbo Yu; Ying Qin; Jing Hui; Yong Zhang; Shengyan Qian; Lin Xu; Yun Liu
Source:
Biochemical systematics and ecology 2022 v.100 pp. 104371
ISSN:
0305-1978
Subject:
Actinidia; butanol; chemotaxonomy; coumarins; ecology; glycosides; lignans; phenylpropanoids; secondary metabolites; spectral analysis
Abstract:
... A previous undescribed dihydrobenzofuran neolignan (1), as well as eleven known phenolic derivatives (2–12) were isolated from the n-butanol fraction of the roots of Actinidia valvata Dunn, including five phenylpropanoids (2–6), four phenolic glycosides (7–10) and two coumarins (11–12). The chemical structures of these compounds were identified by means of extensive spectroscopic analysis and comp ...
DOI:
10.1016/j.bse.2021.104371

14. Combined transcriptome and metabolome analysis of Nerium indicum L. elaborates the key pathways that are activated in response to witches’ broom disease

Author:
Shengjie Wang; Shengkun Wang; Ming Li; Yuhang Su; Zhan Sun; Haibin Ma
Source:
BMC plant biology 2022 v.22 no.1 pp. 291
ISSN:
1471-2229
Subject:
Nerium oleander; Sophora chrysophylla; biosynthesis; brooms; coumarins; disease incidence; flavonoids; gene expression regulation; host-pathogen relationships; hypersensitive response; lignans; linoleic acid; metabolites; metabolome; metabolomics; nicotinamide; ornamental plants; pathogens; phenylpropanoids; phloem; plant hormones; signal transduction; surveys; transcriptome; tricarboxylic acid cycle; unigenes; China
Abstract:
... BACKGROUND: Nerium indicum Mill. is an ornamental plant that is found in parks, riversides, lakesides, and scenic areas in China and other parts of the world. Our recent survey indicated the prevalence of witches’ broom disease (WBD) in Guangdong, China. To find out the possible defense strategies against WBD, we performed a MiSeq based ITS sequencing to identify the possible casual organism, then ...
DOI:
10.1186/s12870-022-03672-z

15. Comparative metabolite fingerprinting of chia, flax and sesame seeds using LC-MS untargeted metabolomics

Author:
Federico I. Brigante; Natalia S. Podio; Daniel A. Wunderlin; Maria V. Baroni
Source:
Food chemistry 2022 v.371 pp. 131355
ISSN:
0308-8146
Subject:
Salvia hispanica; data collection; flax; food chemistry; lignans; metabolites; metabolomics; nutritive value; polyphenols; seeds
Abstract:
... Chia, flax, and sesame seeds are well known for their nutritional quality and are commonly included in bakery products. So far, the development of methods to verify their presence and authenticity in foods is a requisite and a raised need. In this work we applied untargeted metabolomics to propose authenticity markers. Seeds were analyzed by HPLC-MS/MS and 9938 features in negative mode and 9044 i ...
DOI:
10.1016/j.foodchem.2021.131355

16. Consumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials

Author:
Mohammad Hassan Sohouli; Niloufar Haghshenas; Ángela Hernández‐Ruiz; Farzad Shidfar
Source:
Phytotherapy research 2022 v.36 no.3 pp. 1126-1134
ISSN:
0951-418X
Subject:
blood glucose; blood serum; glucose; humans; insulin; insulin resistance; lignans; meta-analysis; metabolism; phytotherapy; research; sesame oil; systematic review
Abstract:
... Sesame, with an oily seed containing oil, lignans, and proteins, is a popular plant that has demonstrated health benefits such as antioxidative, antiobesity, and antiinflammatory effects. In this systematic review and meta‐analysis, we aimed to summarize the effect of sesame seeds and their consumption compared to a control group on blood glucose and insulin resistance in human adults. PubMed/MEDL ...
DOI:
10.1002/ptr.7379

17. Coumarins and lignans from the roots of Zanthoxylum nitidum

Author:
Jian-Hui Su; Ming-Qiang Wang; Li-Ping Zhu; Wei-Qun Yang; Shi-Qin Jiang; Zhong-Xiang Zhao; Zhang-Hua Sun
Source:
Biochemical systematics and ecology 2022 v.101 pp. 104399
ISSN:
0305-1978
Subject:
Oriental traditional medicine; Zanthoxylum nitidum; chemotaxonomy; coumarin; ecology; glycosides; lignans; phytochemicals
Abstract:
... The phytochemical investigation of the Chinese medicine Zanthoxylum nitidum led to the isolation of a new coumarin glycoside (1), seven known coumarins (2–8) and two known lignan glycosides (9–10). Their structures were elucidated based on extensive spectroscopic methods (HRESIMS, 1D and 2D NMR experiments) and by comparison with literature data. The new compound (1) was a linear furanocoumarin gl ...
DOI:
10.1016/j.bse.2022.104399

18. Dirigent gene family is involved in the molecular interaction between Panax notoginseng and root rot pathogen Fusarium solani

Author:
Jie Deng; Ruipan Guan; Tingting Liang; Linlin Su; Feng Ge; Xiuming Cui; Diqiu Liu
Source:
Industrial crops and products 2022 v.178 pp. 114544
ISSN:
0926-6690
Subject:
Fusarium solani; Nicotiana tabacum; Panax notoginseng; Sclerotinia sclerotiorum; biosynthesis; cell walls; genes; lignans; lignin; pathogens; phylogeny; quantitative polymerase chain reaction; root rot; tobacco
Abstract:
... Root rot, mainly caused by Fusarium solani, severely reduces the yield and quality of Panax notoginseng (Burk) F.H. Chen. Dirigent (DIR) proteins catalyze the coupling of lignin monomers during lignin biosynthesis, making them important components of plant defense systems. In this study, a small P. notoginseng DIR gene family was isolated from P. notoginseng. A phylogenetic analysis indicated that ...
DOI:
10.1016/j.indcrop.2022.114544

19. Distribution of lignans in Panicum miliaceum, Fagopyrum esculentum, Fagopyrum tataricum, and Amaranthus hypochondriacus

Author:
Jana Pexová Kalinová; Iveta Marešová; Jan Tříska; Naděžda Vrchotová
Source:
Journal of food composition and analysis 2022 v.106 pp. 104283
ISSN:
0889-1575
Subject:
Amaranthus hypochondriacus; Fagopyrum esculentum; Fagopyrum tataricum; Panicum miliaceum subsp. miliaceum; buckwheat; food composition; lignans; lignin content; roots
Abstract:
... The distribution of lignans within common millet, common buckwheat, tartary buckwheat, and amaranth plants, as well as any differences of their contents within their different varieties and samples from different growing seasons, were determined by LC–MS analyses. Roots were the plant part highest in the total amount of lignans in common buckwheat, tartary buckwheat, and common millet; which is in ...
DOI:
10.1016/j.jfca.2021.104283

20. Effect of microwave exposure to flaxseed on the composition, structure and techno-functionality of gum polysaccharides

Author:
Xiao Yu; Shasha Huang; Fan Yang; Xiaopeng Qin; Chengzhen Nie; Qianchun Deng; Fenghong Huang; Qisen Xiang; Yingying Zhu; Fang Geng
Source:
Food hydrocolloids 2022 v.125 pp. 107447
ISSN:
0268-005X
Subject:
antioxidants; crosslinking; depolymerization; emulsions; enthalpy; gels; hydrocolloids; lignans; linseed; molecular weight; polysaccharides; seed coat; thermogravimetry; viscoelasticity
Abstract:
... The current study aimed to explore the potential influences of microwave exposure to flaxseed (150 g samples, 700 W for 1–5 min) on the several techno-functional properties of flaxseed gum (FG), focusing on the changes in composition, surface morphology and multiscale structure. The results showed that microwave exposure to flaxseed actually resulted in evident etching effect on seed coat and favo ...
DOI:
10.1016/j.foodhyd.2021.107447

21. Effect of ultrasonic pretreatment for lignan accumulation in flax sprouts (Linum usitatissimum L.)

Author:
Yixin Wu; Hong Wang; Fangyang Gao; Yufu Wang; Xinbo Guo; Caisheng Qiu
Source:
Food chemistry 2022 v.370 pp. 131067
ISSN:
0308-8146
Subject:
Linum usitatissimum; biosynthesis; caffeic acid; ferulic acid; flax; food chemistry; lignans; p-coumaric acid; ultrasonics; vegetables
Abstract:
... This study evaluated different ultrasonic treatments for lignan biosynthesis in two varieties of flax sprouts. Results showed that lignans in flax sprouts significantly raised with ultrasonic pretreatment. Secoisolariciresinol diglucoside dramatically increased by about 6-fold at the flax sprouts. Ultrasonic pretreatment could also affect the accumulation of caffeic acid and p-coumaric acid in fla ...
DOI:
10.1016/j.foodchem.2021.131067

22. Genome-wide identification and expression analysis of dirigent gene family in strawberry (Fragaria vesca) and functional characterization of FvDIR13

Author:
Yaqian Shi; Yaru Shen; Bilal Ahmad; Liping Yao; Tiannan He; Jianshuai Fan; Yuhan Liu; Qingxi Chen; Zhifeng Wen
Source:
Scientia horticulturae 2022 v.297 pp. 110913
ISSN:
0304-4238
Subject:
Arabidopsis thaliana; Fragaria vesca; Glomerella cingulata; bioinformatics; computer simulation; disease resistance; gene expression regulation; growth and development; introns; lignans; lignin; metabolism; pathogens; phylogeny; plant growth; plant response; stolons; strawberries
Abstract:
... Dirigent proteins (DIR) are thought to have important roles in lignans or lignin-like molecules production, defensive responses, secondary metabolism, and disease resistance in plants. There is a lack of information about the DIR genes in strawberries (Fragaria vesca). In this study, 33 FvDIR genes were identified and divided into four subfamilies based on the phylogenetic analysis. A detailed bio ...
DOI:
10.1016/j.scienta.2022.110913

23. Hepatoprotective effect of phillygenin on carbon tetrachloride-induced liver fibrosis and its effects on short chain fatty acid and bile acid metabolism

Author:
Cheng Wang; Cheng Ma; Ke Fu; Yanfang Liu; Lihong Gong; Cheng Peng; Yunxia Li
Source:
Journal of ethnopharmacology 2022 v.296 pp. 115478
ISSN:
0378-8741
Subject:
Forsythia suspensa; Oriental traditional medicine; acetic acid; antioxidants; bile acids; butyric acid; carbon; carbon tetrachloride; dried fruit; epithelium; gas chromatography-mass spectrometry; hepatoprotective effect; immunohistochemistry; inflammation; intestinal microorganisms; intestines; intraperitoneal injection; lignans; liquid chromatography; liver; liver cirrhosis; metabolism; metabolomics; mice; models; olive oil; propionic acid; quantitative polymerase chain reaction
Abstract:
... Forsythiae fructus, the dried fruit of Oleaceae plant Forsythia suspensa (Thunb.) Vahl, is a traditional Chinese medicine widely used in clinical practice and has a variety of pharmacological activities, such as anti-inflammation, antioxidation, and hepatoprotection. Phillygenin (PHI), an important fingerprint lignan component of Forsythiae fructus, has prominent hepatoprotective, anti-inflammator ...
DOI:
10.1016/j.jep.2022.115478

24. In vitro cytotoxic activity-guided isolation studies on the underground parts of Valeriana speluncaria Boiss

Author:
Murat Erdoğan; Başak Aru; Ceren Öztürk; Olcay Esin Özdemir; Erdem Yeşilada; Gülderen Yanıkkaya-Demirel; Hasan Kırmızıbekmez
Source:
South African journal of botany 2022 v.149 pp. 315-319
ISSN:
0254-6299
Subject:
Valeriana; cell lines; cytotoxicity; ethyl acetate; fractionation; glucosides; indigenous species; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; phytochemicals
Abstract:
... Two unreported neolignans, speluncarins A (1) and B (2) together with seven known compounds (3–8, 13) were isolated from the underground parts of Valeriana speluncaria Boiss through cytotoxic activity-guided fractionation method. The crude extract, subextracts, main fractions and isolates were evaluated for their in vitro cytotoxic activities against MCF-7 and U87 cancer cell lines as well as HUVE ...
DOI:
10.1016/j.sajb.2022.06.024

25. Inter-specific hybrid sesame with high lignan content in oil reveals increased expression of sesamin synthase gene

Author:
Debabrata Dutta; Ranjana Prasad; Gaurab Gangopadhyay
Source:
Nucleus 2022 v.65 no.1 pp. 7-18
ISSN:
0029-568X
Subject:
Sesamum indicum; biochemical pathways; enzymes; genes; genetic markers; hybrids; interspecific hybridization; lignans; lipid content; phenotypic selection; seed development; sesame oil
Abstract:
... The presence of lignans (sesamin, sesamol) adds pharmaceutical value in the sesame oil. Wild sesame, Sesamum mulayanum, though less oil-yielding but contains remarkably higher lignan in oil. We performed an interspecific hybridization between cultivated Indian sesame (S. indicum) and S. mulayanum to bring a better oil profile in the cultivated sesame. The selected recombinant lines of F₆ generatio ...
DOI:
10.1007/s13237-021-00354-3

26. Interactions between second messengers, SA and MAPK6 signaling pathways lead to chitosan-induced lignan production in Linum album cell culture

Author:
Elaheh Samari; Najmeh Ahmadian Chashmi; Faezeh Ghanati; Reza H. Sajedi; Andrea A. Gust; Farnaz Haghdoust; Mohsen Sharifi; Elisabeth Fuss
Source:
Industrial crops and products 2022 v.177 pp. 114525
ISSN:
0926-6690
Subject:
Linum album; NAD(P)H oxidase (H2O2-forming); biochemical pathways; biosynthesis; calcium; cell culture; chitosan; hydrogen peroxide; imidazole; lignans; mitogen-activated protein kinase; nitrate reductase; nitric oxide; phenylalanine ammonia-lyase; plasma membrane; quantitative polymerase chain reaction; salicylic acid
Abstract:
... Lignans along with their special ecological role in plants have received much attention in recent decades due to their anti-cancer properties. However, the mechanisms regulating their biosynthesis are still largely unknown. Here, we investigated the potential role of certain signaling pathways and their relationships in regulating the biosynthesis of 6-methoxypodophyllotoxin (6MPTOX) through pharm ...
DOI:
10.1016/j.indcrop.2022.114525

27. Iridoids and lignans from Valeriana officinalis L. and their cytotoxic activities

Author:
Dongdong Zhang; Zilong Zhang; Guoqing Wu; Yu Sun; Yi Jiang; Huawei Zhang; Wei Wang; Xiaomei Song; Yuze Li
Source:
Phytochemistry letters 2022 v.49 pp. 125-130
ISSN:
1874-3900
Subject:
Valeriana officinalis; cytotoxicity; iridoids; lignans; neoplasm cells; nuclear magnetic resonance spectroscopy; plant biochemistry
Abstract:
... Two new iridoids (1 and 2), one new lignan (3) together with one known iridoid (4) and twelve known lignans (5－16) were obtained from the roots of Valeriana officinalis L. (V. officinalis). The structures were determined using IR, MS, ¹D and ²D NMR spectroscopy and the absolute configurations of the new structures were deduced by ECD experiments. All of the isolated compounds were assayed for thei ...
DOI:
10.1016/j.phytol.2022.03.018

28. Isatidis Radix and Isatidis Folium: A systematic review on ethnopharmacology, phytochemistry and pharmacology

Author:
Jiao Chen; Zongping Zhu; Tianhui Gao; Yi Chen; Qingsong Yang; Chaomei Fu; Yaning Zhu; Fang Wang; Wan Liao
Source:
Journal of ethnopharmacology 2022 v.283 pp. 114648
ISSN:
0378-8741
Subject:
Internet; Oriental traditional medicine; Orthomyxoviridae; Respiratory syncytial virus; adenosine; antioxidants; cough; databases; erucic acid; fever; heart; herpes simplex; immunity; immunomodulators; influenza; lignans; lungs; pharyngitis; phytochemicals; reproduction; stomach; systematic review; taste; therapeutics; toxicity; viruses
Abstract:
... Isatidis Radix (called Banlangen, BLG in Chinese) and Isatidis Folium (called Daqingye, DQY in Chinese) are common traditional edible-medicinal herbs in detoxifying for thousands of years, have been traditionally applied in traditional Chinese medicine for centuries. Both of them are bitter in taste, coolness in nature, acting on the heart and stomach channels. They are often used to treat influen ...
DOI:
10.1016/j.jep.2021.114648

29. LC-MS-based identification and antioxidant evaluation of small molecules from the cinnamon oil extraction waste

Author:
Ya-Ling Yang; Dalia Adel Al-Mahdy; Miao-Li Wu; Xiao-Tao Zheng; Xiu-Hong Piao; A-Li Chen; Shu-Mei Wang; Quan Yang; Yue-Wei Ge
Source:
Food chemistry 2022 v.366 pp. 130576
ISSN:
0308-8146
Subject:
antioxidant activity; antioxidants; cinnamon; cinnamon oil; cost effectiveness; dissociation; flavanols; flavonols; food chemistry; glycosides; hydrophilicity; industry; lactones; lignans; oils; phenylpropanoids; steam distillation; terpenoids; wastes
Abstract:
... Cinnamon oil is obtained by steam distillation from cinnamon leaves and is usually considered highly cost-effective compared to bark oil, however, which results in tons of waste cinnamon leaves (WCL) discarded annually. By using MS/MS molecular networking (MN) assisted profiling, six main chemical diversities including flavonols and flavones, phenolic acids, lactones, terpenoids, phenylpropanoids ...
DOI:
10.1016/j.foodchem.2021.130576

30. Lignan exposure: a worldwide perspective

Author:
Lucia Rizzolo-Brime; Elida M. Caro-Garcia; Cynthia A. Alegre-Miranda; Mireia Felez-Nobrega; Raul Zamora-Ros
Source:
European journal of nutrition 2022 v.61 no.3 pp. 1143-1165
ISSN:
1436-6207
Subject:
biomarkers; blood; food composition; lignans; plant estrogens; urine
Abstract:
... Dietary lignans are phytoestrogens that are mostly found in plant-based foods, especially whole grains, seeds, nuts, legumes and vegetables. An accurate assessment of lignan exposure is crucial to evaluate their potential health benefits and to establish future recommendations and dietary guidelines. This narrative review aimed to (i) summarize the pros and the cons of the current main assessment ...
DOI:
10.1007/s00394-021-02736-4

31. Lignans and sesquiterpenoids from the stems of Schisandra bicolor var. tuberculata

Author:
Shui-Mei Zhang; Kun Hu; Xiao-Nian Li; Han-Dong Sun; Pema-Tenzin Puno
Source:
Natural products and bioprospecting 2022 v.12 no.1 pp. 19
ISSN:
2192-2195
Subject:
Schisandra; X-ray diffraction; apoptosis; enantiomers; lignans; quantum mechanics; sesquiterpenoids; spectral analysis; tetrahydrofuran
Abstract:
... A pair of new tetrahydrofuran lignan enantiomers, (±)-schibiculatin A [(±)-1], a new enedione lignan, schibiculatin B (2), two new cadinane-type sesquiterpenoids, schibiculatins C (3) and D (4), along with two known seco-cadinane-type sesquiterpenoids (5 and 6) and seven known miscellaneous lignans (7–13) were isolated from the stems of Schisandra bicolor var. tuberculata. The structures of 1–4 we ...
DOI:
10.1007/s13659-022-00342-3

32. Lignans as new chemical markers of a certified Brazilian organic propolis

Author:
Ana Paula Tiveron; Pedro Luiz Rosalen; Antonio Gilberto Ferreira; Sérgio Scherrer Thomasi; Adna Prado Massarioli; Masaharu Ikegaki; Marcelo Franchin; Alan Giovanini de Oliveira Sartori; Severino Matias de Alencar
Source:
Natural product research 2022 v.36 no.8 pp. 2135-2139
ISSN:
1478-6427
Subject:
antioxidant activity; flavonoids; fractionation; lignans; natural resources conservation; nuclear magnetic resonance spectroscopy; propolis; reforestation; research; Brazil
Abstract:
... Commercially certified organic propolis produced in areas of environmental conservation and reforestation forests of Southern Brazil are generally poor in flavonoids, although one of its variants – Brazilian certified organic propolis 1 (OP1) – has shown strong antioxidant activity. The objective was to identify active compounds from OP1 related to its strong antioxidant activity. OP1 ethanolic ex ...
DOI:
10.1080/14786419.2020.1839459

33. Lignans dramatically enhance the resistance of Fraxinus velutina Torr. by adjusting the dominant bacterium group of Agrilus planipennis Fairmaire

Author:
Jianfeng Liu; Runxia Feng; Xiaohong Fu; Jie Zhao; Sufang Zhang; Jianjun Wang; Xiaoyi Wang; Jianrong Wei
Source:
Pest management science 2022 v.78 no.4 pp. 1386-1397
ISSN:
1526-498X
Subject:
Agrilus planipennis; Enterobacteriaceae; Fraxinus velutina; Pseudomonadaceae; Xanthomonadaceae; artificial diets; bacteria; genes; larvae; lignans; midgut; ornamental trees; pest management; phloem; secondary metabolites; transcriptome; wood
Abstract:
... BACKGROUND: Velvet ash (Fraxinus velutina Torr.) is an important wood and ornamental tree species. Emerald ash borer (EAB), Agrilus planipennis Fairmaire, is a major wood borer of velvet ash. The aim of this study was to identify the secondary metabolites of velvet ash involved in regulating the dominant bacterium group of EAB. RESULTS: The amount of lignans in the phloem of infested trees had inc ...
DOI:
10.1002/ps.6755

34. Lignans in Oat and Barley Grains Depending on Genotype and Farming Practice

Author:
Māra Bleidere; Sanita Zute; Natālija Gailāne; Ināra Kantāne; Ida Jākobsone; Vadims Bartkevičs
Source:
Proceedings of the Latvian Academy of Sciences 2022 v.76 no.1 pp. 124-130
ISSN:
2255-890X
Subject:
barley; breasts; diabetes; dietary fiber; genotype; high performance liquid chromatography; lignans; lignin; oats; phytochemicals; prostatic neoplasms; secondary metabolites; tandem mass spectrometry
Abstract:
... Cereals are an important source of vitamins, minerals, dietary fibre, and various phytochemicals, such as plant lignans. Lignans are a group of phenolic compounds that are commonly found in plants as their secondary metabolites. Lignans, found also in foodstuffs such as grains and seeds, are biologically active antioxidants, which reduce the occurrence of diabetes and cardiovascular diseases and p ...
DOI:
10.2478/prolas-2022-0019

35. Meso-Dihydroguaiaretic Acid Ameliorates Acute Respiratory Distress Syndrome through Inhibiting Neutrophilic Inflammation and Scavenging Free Radical

Author:
Yen-Tung Lee; Yu-Li Chen; Yi-Hsuan Wu; Ih-Sheng Chen; Hsun-Shuo Chang; Yi-Hsuan Wang; Shih-Hsin Chang; Yi-Hsiu Wu; Ting-I Kao; Huang-Ping Yu; Tsong-Long Hwang
Source:
Antioxidants 2022 v.11 no.1 pp. -
ISSN:
2076-3921
Subject:
G-protein coupled receptors; acute respiratory distress syndrome; adhesion; elastase; free radicals; humans; inflammation; lignans; lungs; mitogen-activated protein kinase; mortality; neutrophils; pathogenesis; phosphorylation; protein kinase C; superoxide anion; therapeutics
Abstract:
... The pathogenesis of acute respiratory distress syndrome (ARDS) is very complex. Patients with ARDS still suffer high mortality rates. Infiltration and activation of neutrophils in lungs are critical pathogenic factors in ARDS. In this study, we demonstrate that meso-dihydroguaiaretic acid (MDGA), a natural lignan, inhibits inflammatory responses in human neutrophils and ameliorates ARDS in mice. M ...
DOI:
10.3390/antiox11010123

36. Metabolome and transcriptome analyses identify the plant immunity systems that facilitate sesquiterpene and lignan biosynthesis in Syringa pinnatifolia Hemsl.

Author:
Jiaqi Gao; Tianxiao Li; Lichao Jiao; Chao Jiang; Suyile Chen; Luqi Huang; Juan Liu
Source:
BMC plant biology 2022 v.22 no.1 pp. 132
ISSN:
1471-2229
Subject:
Oriental traditional medicine; RNA; Syringa; biosynthesis; fiber cells; gene expression regulation; gene ontology; host-pathogen relationships; immunity; lignans; metabolites; metabolome; microscopy; sesquiterpenoids; shrubs; transcriptome; volatile organic compounds; wood fibers; China
Abstract:
... BACKGROUND: Syringa pinnatifolia Hemsl. is a shrub belonging to the Oleaceae family. The peeled woody stems and roots of S. pinnatifolia are used in Chinese traditional medicine. This plant has been used for centuries, and modern pharmacological research has revealed its medicinal value. However, the wild populations of S. pinnatifolia have been decreasing, and it has been listed as an endangered ...
DOI:
10.1186/s12870-022-03537-5

37. Physicochemical, functional and emulsifying properties of plant protein powder from industrial sesame processing waste as affected by spray and freeze drying

Author:
Elif Ezgi Özdemir; Ahmet Görgüç; Esra Gençdağ; Fatih Mehmet Yılmaz
Source:
Lebensmittel-Wissenschaft + Technologie 2022 v.154 pp. 112646
ISSN:
0023-6438
Subject:
amino acids; bran; color; dispersibility; food industry; freeze drying; ingredients; lignans; plant proteins; spray drying; transportation; ultrasonic treatment; wettability
Abstract:
... This study aimed to produce protein hydrolysates from sesame bran using ultrasound-assisted enzymatic extraction followed by spray-drying (SD) and freeze-drying (FD) techniques. Spray drying parameters highly influenced powder yield (22.8–70.5%), protein yield (23.0–70.4%), drying time (41–149 min) and aw value (0.196–0.288). Therefore, the impacts of SD and FD were assessed after an optimization ...
DOI:
10.1016/j.lwt.2021.112646

38. Plant-derived lignans as potential antiviral agents: a systematic review

Author:
Xin-Ya Xu; Dong-Ying Wang; Yi-Ping Li; Stephen T. Deyrup; Hong-Jie Zhang
Source:
Phytochemistry reviews 2022 v.21 no.1 pp. 239-289
ISSN:
1568-7767
Subject:
Influenza A virus; Internet; antiviral properties; databases; lignans; mechanism of action; norlignans; plant biochemistry; propane; structure-activity relationships; systematic review; therapeutics
Abstract:
... Medicinal plants are one of the most important sources of antiviral agents and lead compounds. Lignans are a large class of natural compounds comprising two phenyl propane units. Many of them have demonstrated biological activities, and some of them have even been developed as therapeutic drugs. In this review, 630 lignans, including those obtained from medicinal plants and their chemical derivati ...
DOI:
10.1007/s11101-021-09758-0

39. Recent advances in interactions between polyphenols and plant cell wall polysaccharides as studied using an adsorption technique

Author:
Anna Siemińska-Kuczer; Monika Szymańska-Chargot; Artur Zdunek
Source:
Food chemistry 2022 v.373 pp. 131487
ISSN:
0308-8146
Subject:
adsorption; antioxidants; cell walls; color; digestive system; flavonoids; food chemistry; functional foods; hemicellulose; humans; lignans; pectins; polyphenols; protective effect; taste
Abstract:
... Polyphenols include flavonoids, phenolic acids, tannins and lignans which are known to have antioxidant, UV protection and antimicrobial properties. Among them the most commonly investigated are flavonoids and phenolic acids, which, due to their plant origin, may interact with the plant cell wall (PCW) components, specifically with its polysaccharides. Knowledge concerning the nature of the intera ...
DOI:
10.1016/j.foodchem.2021.131487

40. The Phenolic Content, Antioxidative Properties and Extractable Substances in Silver Fir (Abies alba Mill.) Branches Decrease with Distance from the Trunk

Author:
Katja Schoss; Rebeka Benedetič; Samo Kreft
Source:
Plants 2022 v.11 no.3 pp. -
ISSN:
2223-7747
Subject:
Abies alba; antioxidant activity; conifers; cosmetics; dietary supplements; drugs; furniture; lignans; phenol; therapeutics; trees; Central European region
Abstract:
... Silver fir (Abies alba Mill.) is one of the most common and valuable conifer tree species in Central Europe, with well-established usage in the construction and furniture industries, as well as the food, health products, pharmaceuticals and cosmetics industries. Silver fir branch extract, a mixture of antioxidative phenols, is produced industrially as a food supplement with a wide range of therape ...
DOI:
10.3390/plants11030333

41. Total Asymmetric Synthesis and Stereochemical Confirmation of (+)- and (−)-Lyoniresinol and Its Deuterated Analogues

Author:
Tuan Minh Luong; Lisa I. Pilkington; David Barker
Source:
Journal of organic chemistry 2022 v.87 no.6 pp. 4254-4262
ISSN:
1520-6904
Subject:
bitterness; enantiomers; isotope dilution technique; lignans; organic chemistry; stable isotopes; stereochemistry; stereoselective synthesis; taste
Abstract:
... Lyoniresinol and its derivatives are lignans which have been isolated from a plethora of plant species. In addition to exhibiting a range of interesting biological activities including anticancer, anti-inflammatory, antimicrobial, and others, these compounds have also been discovered in wines and spirits and shown to have gustatory effects in these alcoholic matrices. (+)-Lyoniresinol 1 is reporte ...
DOI:
10.1021/acs.joc.1c03085

42. Tripterygium hypoglaucum (Levl.) Hutch: A systematic review of its traditional uses, botany, phytochemistry, pharmacology, pharmacokinetics and toxicology

Author:
Jiangping Wei; Liyun Chen; Sijia Gao; Jirui Wang; Yunhong Wang; Zhiwei Zhang; Yuyu Zhang; Xiaomei Zhang; Yong Yang; Dajian Yang
Source:
Pharmacological research 2022 v.3 pp. 100094
ISSN:
2667-1425
Subject:
Oriental traditional medicine; Tripterygium wilfordii; diterpenoids; flavonoids; grasses; homeopathic drugs; human health; immunosuppression; lignans; lupus erythematosus; mechanism of action; neuroprotective effect; pharmacokinetics; psoriasis; research; rheumatoid arthritis; sesquiterpenoids; systematic review; therapeutics; toxic substances; toxicity; toxicology; triterpenoids
Abstract:
... Tripterygium hypoglaucum (Levl.) Hutch (THH) is the source plant of a traditional Chinese medicine named Kunmingshanhaitang, which was first recorded in Compendium of Materia Medica. Like Tripterygium wilfordii Hook f. (TWH), THH is also widely used in the treatment of various autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and psoriasis. The therapeutic effect of T ...
DOI:
10.1016/j.prmcm.2022.100094

43. Triterpenoids and lignans from Schisandra chinensis and their inhibition activities of Cdc25A/B phosphatases

Author:
Qian-Qian Zhao; Wen-Jun Wei; Ya Li; Kun Gao
Source:
Natural product research 2022 v.36 no.3 pp. 754-759
ISSN:
1478-6427
Subject:
Schisandra chinensis; lignans; research; spectroscopy; triterpenoids
Abstract:
... Three new highly modified lanostane triterpenoids schisanchinlactone A-C (1–3), together with six known compounds (4–9) were isolated from the stems and leaves of Schisandra chinensis. Their structures were established by extensive spectroscopic analyses. Compounds 7 and 8 showed significant inhibition of Cdc25A phosphatase with inhibitory rates of 85.5% and 98.1%, respectively, at the concentrati ...
DOI:
10.1080/14786419.2020.1802268

44. Valorisation of Crocus sativus flower parts for herbal infusions: impact of brewing conditions on phenolic profiling, antioxidant capacity and sensory traits

Author:
Luisa Bellachioma; Gabriele Rocchetti; Camilla Morresi; Erika Martinelli; Luigi Lucini; Gianna Ferretti; Elisabetta Damiani; Tiziana Bacchetti
Source:
International journal of food science & technology 2022 v.57 no.6 pp. 3838-3849
ISSN:
0950-5423
Subject:
Crocus sativus; alkylphenols; anthocyanins; antioxidant activity; antioxidants; cold; flavonols; flowers; lignans; multivariate analysis; polyphenols; saffron; temperature
Abstract:
... Saffron production from Crocus sativus flowers produces large amounts of by‐products that may represent an excellent source of polyphenols. The aim of this work was to evaluate infusions originating from different brewing processes and from different saffron flower portions, in terms of both functional and sensory traits. For this aim, total polyphenols and total flavonoids, in vitro antioxidant a ...
DOI:
10.1111/ijfs.15713

45. Variation of lignan content and α-glucosidase inhibitory activity of Schisandra chinensis fruit at different maturation stages: Comparison with stem, leaf and seed

Author:
Solip Lee; Sang Won Yeon; Ayman Turk; Se Hwan Ryu; Jiae Seo; Ki Yong Lee; Bang Yeon Hwang; Hanna Shin; Mi Kyeong Lee
Source:
Scientia horticulturae 2022 v.293 pp. 110679
ISSN:
0304-4238
Subject:
Schisandra chinensis; cultivars; fruit maturity; fruits; harvest date; leaves; lignans
Abstract:
... The fruit of Schisandra chinensis has been used for the treatment of various metabolic diseases for a long time. The bioactive constituents of the fruit are known as lignans with dibenzocyclooctadienes skeletons. In this study, changes in the content of four main lignans of S. chinensis, schizandrin (S1), schizandrin A (S2), gomisin N (S3) and wuweizisu C (S4), and anti-diabetic activities at the ...
DOI:
10.1016/j.scienta.2021.110679

46. α-Glucosidase inhibitive diarylheptanoids from Ottelia acuminata var. acuminata, a traditional vegetable of Bai Nationality in Yunnan

Author:
Hong-Xing Liu; Jun-Zeng Ma; Yan-Song Ye; Jian-Jun Zhao; Shi-Jie Wan; Xin-Yue Hu; Gang Xu
Source:
Natural products and bioprospecting 2022 v.12 no.1 pp. 22
ISSN:
2192-2195
Subject:
Ottelia; acarbose; alkaloids; coumarin; diabetes mellitus; flavones; lignans; metabolites; nationalities and ethnic groups; polyacetylenes; sesquiterpenoids; therapeutics; vegetables; China
Abstract:
... Diabetes is an urgent health issue characterized by ethnic and regional variations, and is inseparable from the different dietary habits. It is worthy to note that the incidence of diabetes in Bai nationality has been reported to be much lower than Han in China. As a daily vegetable of Bai, the phytochemical and antidiabetic study of Ottelia acuminata var. acuminata had not been carried out. In th ...
DOI:
10.1007/s13659-022-00341-4

47. (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis

Author:
Daiki Oikawa; Satoshi Yamashita; Seiji Takahashi; Toshiyuki Waki; Koichi Kikuchi; Takaaki Abe; Takane Katayama; Toru Nakayama
Source:
Biochemical and biophysical research communications 2022 v.590 pp. 158-162
ISSN:
0006-291X
Subject:
Escherichia coli; active sites; dietary supplements; enzymes; intestines; kidney diseases; kidneys; lignans; mice; morbidity; pathogenesis; phytochemicals; pyridoxal; research; sulfates; therapeutics; toxins; tryptophan
Abstract:
... The progression of chronic kidney disease (CKD) increases the risks of cardiovascular morbidity and end-stage kidney disease. Indoxyl sulfate (IS), which is derived from dietary l-tryptophan by the action of bacterial l-tryptophan indole-lyase (TIL) in the gut, serves as a uremic toxin that exacerbates CKD-related kidney disorder. A mouse model previously showed that inhibition of TIL by 2-aza-l-t ...
DOI:
10.1016/j.bbrc.2021.12.088

48. A Comparative Study on Photo-Protective and Anti-Melanogenic Properties of Different Kadsura coccinea Extracts

Author:
Joong Suk Jeon; He Mi Kang; Ju Ha Park; Jum Soon Kang; Yong Jae Lee; Young Hoon Park; Byoung Il Je; Sun Young Park; Young Whan Choi
Source:
Plants 2021 v.10 no.8 pp. -
ISSN:
2223-7747
Subject:
Kadsura coccinea; apoptosis; comparative study; flavonoids; fruits; gene expression; human health; irradiation; keratinocytes; leaves; lignans; melanin; melanocytes; polyphenols; protein phosphorylation; radiation resistance; traditional medicine; transcription factors; triterpenoids; viability; China; Korean Peninsula; Thailand
Abstract:
... Kadsura coccinea (KC), a beneficial plant for human health, has been used for centuries in China, Thailand, and Korea in folk medicine and food. There is evidence supporting the biological effects of highly bioactive ingredients in KC such as lignans, triterpenoids, flavonoids, phenolic acids, steroids, and amino acids. In this study, we aimed to explore the effects, functions, and mechanisms of t ...
DOI:
10.3390/plants10081633

49. A comparative study on the metabolites profiling of linseed cakes from Egyptian cultivars and antioxidant activity applying mass spectrometry-based analysis and chemometrics

Author:
Reham Hassan Mekky; Essam Abdel-Sattar; Antonio Segura-Carretero; María del Mar Contreras
Source:
Food chemistry 2022 pp. 133524
ISSN:
0308-8146
Subject:
Linum usitatissimum; antioxidant activity; byproducts; cakes; chemometrics; cluster analysis; comparative study; coumarins; cultivars; cyanogenic glycosides; flavonoids; food chemistry; food industry; jasmonic acid; lignans; linseed; metabolites; nucleosides; oils; peptides; phenols; principal component analysis; traceability
Abstract:
... Linseed (Linum usitatissimum L.) is an economically important crop worldwide. After the oil extraction, the cake is generated as a by-product. This study addresses a comprehensive metabolites profiling of the cakes of four Egyptian cultivars of linseed via RP-HPLC-DAD-QTOF-MS and MS/MS with chemometrics. Totally, 162 metabolites were detected in the samples under investigation being classified int ...
DOI:
10.1016/j.foodchem.2022.133524

50. A comprehensive review on ethnobotanical, phytochemical and pharmacological aspects of Rhus chinensis Mill

Author:
Meichen Li; Andong Wang; Yunqiang Zhang; Tingting Han; Lu Guan; Dongxue Fan; Jianyu Liu; Yongnan Xu
Source:
Journal of ethnopharmacology 2022 v.293 pp. 115288
ISSN:
0378-8741
Subject:
Rhus chinensis; antioxidants; coumarins; ethnobotany; flavonoids; herbal medicines; lignans; pharmacokinetics; quality control; therapeutics; toxicology; traditional medicine; triterpenoids
Abstract:
... Rhus chinensis Mill., firstly recorded as herbal medicine in Shan Hai Jing, have been used for thousands of years to treat various diseases. This review targets on the ethnomedicinal applications of R. chinensis and to gather the phytochemical, pharmacological and toxicological data which support the therapeutic potential of R. chinensis in treatment on different diseases, with emphasis on the nat ...
DOI:
10.1016/j.jep.2022.115288

51. A database-guided integrated strategy for comprehensive chemical profiling of traditional Chinese medicine

Author:
Ya-Liu Fan; Run-Zhou Liu; Qin Tan; Heng-Li Zhao; Min Song; Rui Wang; Ping Li; Hua Yang
Source:
Journal of chromatography 2022 v.1674 pp. 463145
ISSN:
0021-9673
Subject:
Oriental traditional medicine; chromatography; databases; flavonoids; iridoid glycosides; lignans; liquids; nucleosides; oligosaccharides; sesquiterpenoids
Abstract:
... A comprehensive chemical profiling of traditional Chinese medicine is the basic issue for further pharmacological research and quality assessment. To facilitate chemical identification and potential components discovery, the present study proposed an integrated identification strategy guided by a self-built component database constructed from literatures to carry out the global profiling of comple ...
DOI:
10.1016/j.chroma.2022.463145

52. A method for a comprehensive lipidomic analysis of flaxseed (Linum usitatissimum) with the use of LC–Q-TOF-MS and dispersive micro-solid-phase (μDSPE) extraction

Author:
Inal Bakhytkyzy; Weronika Hewelt-Belka; Agata Kot-Wasik
Source:
Food chemistry 2022 v.381 pp. 132290
ISSN:
0308-8146
Subject:
Linum usitatissimum; diabetes; food chemistry; lignans; linseed; linseed meal; lipidomics; oils; stroke
Abstract:
... Flaxseed (FS) is one of the richest sources of α-linolenic acid oil and lignans, and it is suggested that the consumption of flaxseed may contribute to the prevention of certain chronic diseases such as many types of cancer, diabetes, cardiovascular diseases and cerebrovascular stroke. Here, we demonstrate a new method for comprehensive FS lipidome profiling with the use of LC–Q-TOF-MS and dispers ...
DOI:
10.1016/j.foodchem.2022.132290

53. A new lignan from the stem bark of Fagraea fragrans Roxb

Author:
Suthida Rattanaburi; Kaodeeya Kaikaew; Ramida Watanapokasin; Souwalak Phongpaichit; Wilawan Mahabusarakamb
Source:
Natural product research 2022 v.36 no.7 pp. 1851-1856
ISSN:
1478-6427
Subject:
Fagraea; antibacterial properties; bark; lignans; research; spectroscopy; toxicity
Abstract:
... A new lignan, named fagraeanolide (1), and 14 known compounds were isolated from the stem bark of Fagraea fragrans Roxb. Their structures were determined by spectroscopic methods. Fagraeanolide is the first identified oxofurofuran lignan from the genus Fagraea, while β-boswelic acid (4), gentiogenol (5), 3-(4-hydroxy-3-methoxyphenyl)-acrylic acid octacosyl ester (7) and pinoresinol (14) were isola ...
DOI:
10.1080/14786419.2020.1821020

54. A new neolignan and a new biphenylpropanoid from the leaves of Cupressus funebris Endl.

Author:
Si-Yu Zhong; Hong-Yu Jiang; Li-Ping Wu; Meng-Ying Liu; Ya-Rui Yu; Cheng-Rong Li; Jing Huang
Source:
South African journal of botany 2021 v.139 pp. 140-147
ISSN:
0254-6299
Subject:
Cupressus funebris; antioxidant activity; ascorbic acid; circular dichroism spectroscopy; free radicals; lignans; propane
Abstract:
... A new neolignan, (-)-(7S, 8R)-3‑methoxy-4', 7-epoxy-8, 5'-neolignane-5, 9, 3', 9′-tetraol (1) and a new biphenylpropanoid, 1, 2-epoxy-1-(3', 4'-dihydroxyphenyl-)-3-(2'', 3'', 5''-trihydroxyphenyl-) propane (2), together with eight known compounds (3-10), were isolated from the 95% EtOH extract of the leaves of Cupressus funebris Endl. Their structures were determined by spectroscopic methods inclu ...
DOI:
10.1016/j.sajb.2021.02.003

55. A pair of new lignan enantiomers from Croton tiglium

Author:
Yan Lu; Chun-Wang Meng; Hai-Guo Su; Liang Xiong; Hong-Zhen Shu; Jie Liu; Qiao Lin; Cheng Peng; Xiao-Yu Cao; Ou Dai
Source:
Biochemical systematics and ecology 2021 v.99 pp. 104333
ISSN:
0305-1978
Subject:
Croton tiglium; chemotaxonomy; circular dichroism spectroscopy; ecology; enantiomers; lignans
Abstract:
... A pair of new 3′,7-epoxy-8,4′-oxyneolignan enantiomers [(+)-1 and (−)-1] as well as a known phenylpropanoid (2) were isolated from the seeds of Croton tiglium Linn. Their structures were established based on extensive spectroscopic analyses. The absolute configurations of (+)-1 and (−)-1 were determined by NMR data calculations and electronic circular dichroism calculations. All compounds were iso ...
DOI:
10.1016/j.bse.2021.104333

56. A review of the ethnomedicinal uses, chemistry, and pharmacological properties of the genus Acanthus (Acanthaceae)

Author:
Patrícia Matos; Maria Teresa Batista; Artur Figueirinha
Source:
Journal of ethnopharmacology 2022 v.293 pp. 115271
ISSN:
0378-8741
Subject:
animals; antimicrobial properties; antioxidants; chemical constituents of plants; chemistry; flavonoids; gastrointestinal system; geographical distribution; glycosides; lignans; reproductive system; therapeutics; toxicity; traditional medicine; triterpenoids; urinary tract
Abstract:
... The Acanthus genus belongs to the Acanthaceae family, and its species are distributed in all continents, mainly in tropical and subtropical regions. Several traditional applications are referred to, but few scientific studies validate them. Despite this, studies in animal models corroborate some of its uses in folk medicine, such as anticancer, antidiabetic, anti-inflammatory, and antinociceptive, ...
DOI:
10.1016/j.jep.2022.115271

57. A review of the phytochemistry and pharmacology of Kadsura heteroclita, an important plant in Tujia ethnomedicine

Author:
Mengyun Wang; Sai Jiang; Hanwen Yuan; Salman Zafar; Nusrat Hussain; Yuqing Jian; Bin Li; Limin Gong; Caiyun Peng; Changxiao Liu; Wei Wang
Source:
Journal of ethnopharmacology 2021 v.268 pp. 113567
ISSN:
0378-8741
Subject:
Kadsura heteroclita; Oriental traditional medicine; analgesics; antiretroviral agents; flora; hepatitis; hepatoprotective effect; herbal medicines; ingredients; lignans; medicinal plants; phytochemicals; quality control; rheumatoid arthritis; secondary metabolites; therapeutics; toxicity; triterpenoids; China
Abstract:
... Kadsura heteroclita (Roxb.) Craib (traditionally known as “Xue Tong”) is an important member of the economically and medicinally important plant family Schisandraceae. “Xue Tong” is an imperative ingredient of the Tujia ethnomedicine, traditionally used for the treatment of rheumatoid arthritis (RA), hepatitis, and muscles and joint spasm. The plant is known to be a rich source of lignans and trit ...
DOI:
10.1016/j.jep.2020.113567

58. A review on the ethnobotany, phytochemistry, pharmacology and toxicology of butterbur species (Petasites L.)

Author:
Łukasz Kulinowski; Simon Vlad Luca; Mirjana Minceva; Krystyna Skalicka-Woźniak
Source:
Journal of ethnopharmacology 2022 v.293 pp. 115263
ISSN:
0378-8741
Subject:
Petasites; allergic rhinitis; anti-allergic agents; asthma; biodiversity; bronchitis; central nervous system; cough; ethnobotany; flavonoids; flora; gastrointestinal system; geographical distribution; humans; hypertension; lignans; migraine; monoterpenoids; pandemic; pharmacology; polyphenols; sesquiterpenoids; taxonomy; toxicity; toxicology; traditional medicine
Abstract:
... Petasites (butterbur, Asteraceae) species have been used since Ancient times in the traditional medicine of Asian and European countries to treat central nervous system (migraine), respiratory (asthma, allergic rhinitis, bronchitis, spastic cough), cardiovascular (hypertension), gastrointestinal (ulcers) and genitourinary (dysmenorrhea) disorders. This study summarized and discussed the traditiona ...
DOI:
10.1016/j.jep.2022.115263

59. A sustainable and integrated natural surfactant mediated microwave-assisted extraction technique enhances the extraction of phytochemicals from plants

Author:
Zelin Wang; Hongyi Pan; Jian Xu; Yuanhang Chang; Chang Liu; Ying Zhang; Han Yang; Congjia Duan; Jin Huang; Yujie Fu
Source:
Industrial crops and products 2022 v.184 pp. 115043
ISSN:
0926-6690
Subject:
Eleutherococcus senticosus; chlorogenic acid; coumarin; ethanol; experimental design; foams; free radicals; hydrophilicity; hydrophobicity; industry; lignans; liquids; microwave treatment; phytochemicals; protocatechuic acid; saponins; solvents; surfactants; temperature; ultrasonic treatment
Abstract:
... Natural surfactant mediated microwave-assisted extraction (NSM-MAE) technique was developed and performed for the simultaneous extraction of hydrophilic and hydrophobic phytochemicals from plant matrix, such as phenolic acid, coumarin, bisepoxy lignan and phenylpropanoid from Acanthopanax senticosus stems. The natural surfactant soapnut saponin (SS) ethanol solution was chosen as the best solvent ...
DOI:
10.1016/j.indcrop.2022.115043

60. A trace alkaloid, oleraisoindole A from Portulaca oleracea L. and its anticholinesterase effect

Author:
Yifei Ma; Xuetao Li; Wenjie Zhang; Xixiang Ying; Didier Stien
Source:
Natural product research 2021 v.35 no.2 pp. 350-353
ISSN:
1478-6427
Subject:
Portulaca oleracea; alkaloids; electrospray ionization mass spectrometry; lignans; mass; research
Abstract:
... A new trace alkaloid possessing the lignan structure, named oleraisoindole A, was obtained from the extract of the Portulaca oleracea L.. The structure of oleraisoindole A was elucidated by 1D and 2D NMR and high resolution electrospray ionization time-of-flight mass spectroscopic methods. The compound presented an anticholinesterase effect with the IC₅₀ value of 60.4 μM. ...
DOI:
10.1080/14786419.2019.1627356

61. Aconitum carmichaelii Debeaux: A systematic review on traditional use, and the chemical structures and pharmacological properties of polysaccharides and phenolic compounds in the roots

Author:
Yu-Ping Fu; Yuan-Feng Zou; Fei-Yi Lei; Helle Wangensteen; Kari Tvete Inngjerdingen
Source:
Journal of ethnopharmacology 2022 v.291 pp. 115148
ISSN:
0378-8741
Subject:
Aconitum carmichaelii; Internet; Oriental traditional medicine; analgesics; benzoic acid; biodegradability; flavonoids; heart failure; immunomodulators; intestines; lignans; myocardial infarction; phenylpropanoids; polysaccharides; rheumatoid arthritis; systematic review; China
Abstract:
... Aconitum carmichaelii, belonging to the Ranunculaceae family, is a widely used traditional herbal plant in Asian countries, especially in China. The lateral (“Fuzi”) and mother (“Chuanwu”) roots are the two main plant parts used in Traditional Chinese Medicine (TCM), where they are used in the treatment of acute myocardial infarction, heart failure, rheumatoid arthritis, and as analgesics. In orde ...
DOI:
10.1016/j.jep.2022.115148

62. Amino ether analogues of 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan and their activity against drug-resistant bacteria

Author:
Guillermo Núñez-Mojica; Martha L. Hernández-Carrillo; Francisco G. Avalos-Alanís; Elvira Garza-González; Verónica M. Rivas-Galindo; David A. Silva-Mares; Marc-Antoine Bazin; Pascal Marchand; María del Rayo Camacho-Corona
Source:
Phytochemistry letters 2022 v.50 pp. 57-60
ISSN:
1874-3900
Subject:
Enterococcus faecium; Larrea tridentata; Mycobacterium tuberculosis; active ingredients; antibacterial properties; drug resistance; lignans; plant biochemistry; spectral analysis
Abstract:
... Larrea tridentata antibacterial lignan 4,4′-dihydroxy-3-methoxy-6,7′-cyclolignan (1) was derivatized to obtain eleven new amino ether derivatives (2 A-12 C). The structural elucidation of compounds was performed by analysis of 1D- and 2D NMR spectral data and HRESIMS. The antibacterial activity of compounds was determined against nine drug-resistant bacteria and two strains of Mycobacterium tuberc ...
DOI:
10.1016/j.phytol.2022.05.004

63. An integrated strategy using LC-MS/MS combined with in vivo microdialysis for the simultaneous determination of lignans of Schisandra chinensis (Turcz.) Baill. Fructus and endogenous neurotransmitters: application in pharmacokinetic and pharmacodynamic studies

Author:
Jun Fu; Hongxu Zhang; Shu Liu; Jiajie Wu; Yuying Zhang; Yang Gao; Fengrui Song; Yuhua Qin; Xiuli Hu; Zhongying Liu
Source:
Food & function 2021 v.12 no.19 pp. 8932-8945
ISSN:
2042-650X
Subject:
Alzheimer disease; Schisandra chinensis; absorption; fruits; histopathology; immunohistochemistry; lignans; mechanism of action; memory; microdialysis; neuroprotective effect; neurotransmitters; oral administration; pharmacodynamics; pharmacokinetics
Abstract:
... Schisandra chinensis (Turcz.) Baill Fructus (SCF) is the ripe fruit of Schisandra chinensis (Turcz.) Baill, and is often used as a neuroprotective drink. Modern pharmacological studies have shown that lignans are the main bioactive components responsible for neuroprotection and have potential in the treatment of Alzheimer's disease (AD). However, the mechanism of action of SCF in the treatment of ...
DOI:
10.1039/d1fo01682b

64. Anti-Inflammatory Benzofuran Neolignans from the Fruits of Canarium album (Chinese Olive)

Author:
Jiming Li; Ru Wang; Yihai Wang; Jia Zeng; Zeyong Xu; Jingwen Xu; Xiangjiu He
Source:
Journal of agricultural and food chemistry 2022 v.70 no.4 pp. 1122-1133
ISSN:
1520-5118
Subject:
Canarium album; circular dichroism spectroscopy; enantiomers; food chemistry; fruits; interleukin-6; lignans; macrophages; nitric oxide; phytochemicals; China
Abstract:
... Chinese olive is a well-known fruit in China. In this study, we explored anti-inflammatory phytochemicals of Chinese olive fruit, which led to the isolation of nine pairs of new enantiomers of benzofuran neolignans (1a/1b–9a/9b). Among them, the planar structures of compounds 1–3 were undescribed previously, and the absolute configurations of all compounds were reported first. Their stereostructur ...
DOI:
10.1021/acs.jafc.1c06457

65. Anti-influenza activity of compounds isolated from the leaves of Elsholtzia rugulosa and their chemotaxonomic significance

Author:
Shi-yan Feng; Lu Zhang; Lun-li Xiang; Rong-tao Li; Xuan-qin Chen; Fei Yu; Jin-dong Zhong
Source:
Biochemical systematics and ecology 2022 v.103 pp. 104441
ISSN:
0305-1978
Subject:
Elsholtzia; benzene; chemotaxonomy; diterpenoids; ecology; flavonoids; lignans; monoterpenoids; phenolic acids; phenylpropanoids; sesquiterpenoids
Abstract:
... A phytochemical investigation on the leaves of Elsholtzia rugulosa resulted in the isolation and identification of thirty compounds, including four flavonoids (1–4), two benzene derivatives, two lignans (7 and 8), three phenylpropanoids (9–11), three phenolic acid (12–14), five sesquiterpenes (15–19), five nor-sesquiterpenes (20–24), one diterpenoids (25), and four monoterpenoids (26–30). Among of ...
DOI:
10.1016/j.bse.2022.104441

66. Antioxidant and Neuroprotective Activity of Extra Virgin Olive Oil Extracts Obtained from Quercetano Cultivar Trees Grown in Different Areas of the Tuscany Region (Italy)

Author:
Maria Cristina Barbalace; Lorenzo Zallocco; Daniela Beghelli; Maurizio Ronci; Serena Scortichini; Maria Digiacomo; Marco Macchia; Maria Rosa Mazzoni; Dennis Fiorini; Antonio Lucacchini; Silvana Hrelia; Laura Giusti; Cristina Angeloni
Source:
Antioxidants 2021 v.10 no.3 pp. -
ISSN:
2076-3921
Subject:
cultivars; extra-virgin olive oil; flavones; glutathione-disulfide reductase; heme oxygenase (biliverdin-producing); inflammation; lignans; mitochondria; neuroplasticity; neuroprotective effect; oleocanthal; oxidative stress; phenol; proteomics; provenance; quinones; therapeutics; thioredoxins; Italy
Abstract:
... Neurodegenerative diseases are driven by several mechanisms such as inflammation, abnormal protein aggregation, excitotoxicity, mitochondrial dysfunction and oxidative stress. So far, no therapeutic strategies are available for neurodegenerative diseases and in recent years the research is focusing on bioactive molecules present in food. In particular, extra-virgin olive oil (EVOO) phenols have be ...
DOI:
10.3390/antiox10030421

67. Assessment of potential winter hardiness in winter bread wheat cultivars and genotypes by analyzing autofluorescence in seedling tissues

Author:
I. V. Karkhardin; A. A. Konovalov; N. P. Goncharov
Source:
Trudy po prikladnoj botanike, genetike i selekcii 2021 v.182 no.1 pp. 33-40
ISSN:
2619-0982
Subject:
Russia; Yugoslavia; alleles; biocenosis; cinnamyl alcohol dehydrogenase; cultivars; fluorescence; frost resistance; glycosides; isozymes; lignans; lignin; lignin content; metabolism; overwintering; seedlings; winter; winter hardiness; winter wheat
Abstract:
... Background. Winter crops are the most productive component of agricultural biocenoses. In Russia, winter wheat suffers the greatest losses in winter, so a search for traits marking high or low winter hardiness in autumn-sown genotypes, including improved cultivars, is needed to assess their potential for overwintering. One of such markers of high winter hardiness is an increased lignin content in ...
DOI:
10.30901/2227-8834-2021-1-33-40

68. Asymmetric total synthesis of four bioactive lignans using donor–acceptor cyclopropanes and bioassay of (−)- and (+)-niranthin against hepatitis B and influenza viruses

Author:
Ryotaro Ota; Daichi Karasawa; Mizuki Oshima; Koichi Watashi; Noriko Shimasaki; Yoshinori Nishii
Source:
RSC advances 2022 v.12 no.8 pp. 4635-4639
ISSN:
2046-2069
Subject:
antiviral properties; bioassays; hepatitis B; influenza; lignans; matairesinol
Abstract:
... The asymmetric total synthesis of four lignans, dimethylmatairesinol, matairesinol, (−)-niranthin, and (+)-niranthin has been achieved using reductive ring-opening of cyclopropanes. Moreover, we performed bioassays of the synthesized (+)- and (−)-niranthins using hepatitis B and influenza viruses, which revealed the relationship between the enantiomeric structure and the anti-viral activity of nir ...
DOI:
10.1039/d2ra00499b

69. Beer and beer-based beverage contain lignans

Author:
Josef Balík; Pavel Híc; Jan Tříska; Naděžda Vrchotová; Pavel Smetana; Libor Smutek; Bo-Anne Rohlik; Milan Houška
Source:
Journal of food science and technology 2021 v.58 no.2 pp. 581-585
ISSN:
0022-1155
Subject:
Picea abies; beers; food science; human health; lignans; odors; taste
Abstract:
... Lignans are members of a broad group of plant phenols that can positively affect human health. They occur in negligible quantities in processed foodstuffs such as lager beer. The aim of this work was to utilize the high levels of lignans in the knots of spruce trees (Picea abies) to increase the lignans content in beer, without negatively impacting the natural taste and aroma. By means of lignans ...
DOI:
10.1007/s13197-020-04570-8

70. Bioactive neolignans and lignans from the roots of Paeonia lactiflora

Author:
Huan XIA; Jing-Fang ZHANG; Ling-Yan WANG; Gui-Yang XIA; Ya-Nan WANG; Yu-Zhuo WU; Peng-Cheng LIN; Liang XIONG; Sheng LIN
Source:
Chinese journal of natural medicines 2022 v.20 no.3 pp. 210-214
ISSN:
1875-5364
Subject:
Paeonia lactiflora; X-ray diffraction; carboxylesterase; circular dichroism spectroscopy; enantiomers; humans; lignans; spectral analysis
Abstract:
... Two new neolignans and one new lignan (1–3) were obtained from the roots of Paeonia lactiflora. Their structures were unambiguously elucidated based on extensive spectroscopic analysis, single-crystal X-ray crystallography, and the calculated and experimental electronic circular dichroism (ECD) spectra. Compound 1 was a racemic mixture and successfully resolved into the anticipated enantiomers via ...
DOI:
10.1016/S1875-5364(22)60164-X

71. Bioassay-guided fractionation and isolation of Arctigenin from Saussurea heteromalla for in vitro and in silico cytotoxic activity against HeLa cells

Author:
Azra Batool; Ghulam Abbas Miana; Mahboob Alam; Muhammad Tariq Khan; Muhammad Muddassir; Wajid Zaman; Saifullah Khan; Akhtar Aman; Ameer Khusro; Mariadhas Valan Arasu; Naif Abdullah Al-Dhabi; Ki Choon Choi; Muhammad Umar Khayam Sahibzada
Source:
Physiological and molecular plant pathology 2022 v.117 pp. 101749
ISSN:
0885-5765
Subject:
Himalaiella heteromalla; Saussurea; computer simulation; cytotoxicity; fractionation; lignans; matairesinol; mechanism of action; neoplasm antigens; plant pathology; secondary metabolites; traditional medicine; uterine cervical neoplasms
Abstract:
... Ethnopharmacological relevance of Saussurea species to anticancer compounds instigated the present research. Therefore to search the bioactive anticancer lead compound (s) scientifically bioactivity guided fractionation of Saussurea heteromalla (Compositae) was carried out that resulted in the isolation and characterization of three butyrolactone (lignan) secondary metabolites i.e. arctigenin (1), ...
DOI:
10.1016/j.pmpp.2021.101749

72. Bioinspired Selective Synthesis of Heterodimer 8–5′ or 8–O–4′ Neolignan Analogs

Author:
Kui Dong; Chuang-Yuan Zhao; Xiao-Ju Wang; Li-Zhu Wu; Qiang Liu
Source:
Organic letters 2021 v.23 no.7 pp. 2816-2820
ISSN:
1523-7052
Subject:
acetates; air; ambient temperature; catalysts; cross-coupling reactions; lignans; oxidants; oxidation
Abstract:
... The bioinspired synthesis of heterodimer neolignan analogs is reported by single-electron oxidation of both alkenyl phenols and phenols individually, followed by a combination of the resultant radicals. This oxidative radical cross-coupling strategy can afford heterodimer 8–5′ or 8–O–4′ neolignan analogs selectively with the use of air as the terminal oxidant and copper acetate as the catalyst at ...
DOI:
10.1021/acs.orglett.1c00762

73. Biological functions of lignans in plants

Author:
Katarína Ražná; Janka Nôžková; Angéla Vargaová; Ľubomír Harenčár; Marie Bjelková
Source:
Agriculture = Pol̕nohospodárstvo 2021 v.67 no.4 pp. 155-165
ISSN:
1338-4376
Subject:
agriculture; antioxidants; flax; genotype; lignans; linseed; nutrition; provenance
Abstract:
... Naturally occurring lignans are present in seeds, nuts, cereals, vegetables, and fruits. Lignans play various roles in plants and their multipurpose functions of different organisms including humans is considerable. They are involved in plant defence mechanisms through their antioxidant, antiviral, antibacterial, and antifungal properties. The lignans content may be affected by a variety of factor ...
DOI:
10.2478/agri-2021-0014

74. Biotransformation of α-asarone by Alternaria longipes CGMCC 3.2875

Author:
Jian ZOU; Shuai ZHANG; Huan ZHAO; Yong-Heng WANG; Zheng-Qun ZHOU; Guo-Dong CHEN; Dan HU; Ning LI; Xin-Sheng YAO; Hao GAO
Source:
Chinese journal of natural medicines 2021 v.19 no.9 pp. 700-705
ISSN:
1875-5364
Subject:
Alternaria longipes; X-ray diffraction; biotransformation; cytotoxicity; epigallocatechin gallate; lignans; metabolites; quantum mechanics
Abstract:
... Biotransformation of α-asarone by Alternaria longipes CGMCC 3.2875 yielded two pairs of new neolignans, (+) (7S, 8S, 7′S, 8′R) iso-magnosalicin (1a)/(–) (7R, 8R, 7′R, 8′S) iso-magnosalicin (1b) and (+) (7R, 8R, 7′S, 8’R) magnosalicin (2a)/(–) (7S, 8S, 7′R, 8’S) magnosalicin (2b), and four known metabolites, (±) acoraminol A (3), (±) acoraminol B (4), asaraldehyde (5), and 2, 4, 5-trimethoxybenzoic ...
DOI:
10.1016/S1875-5364(21)60088-2

75. Bis-iridoids and other constituents from Scabiosa semipapposa

Author:
Samia Bendamene; Naima Boutaghane; Charlotte Sayagh; Abdulmagid Alabdul Magid; Zahia Kabouche; Chawki Bensouici; Laurence Voutquenne-Nazabadioko
Source:
Phytochemistry letters 2022 v.49 pp. 202-210
ISSN:
1874-3900
Subject:
Scabiosa; antioxidant activity; antioxidants; chemotaxonomy; flavonoids; glycosides; iridoids; lignans; mass spectrometry; phenol; spectral analysis
Abstract:
... Six undescribed bis-iridoids named Semipapposiridoids A–F (1–6) together with seventeen known compounds were obtained from the roots and aerial parts of Scabiosa semipapposa Salzm. ex DC. Among the known compounds, three lignans were isolated for the first time in Scabiosa species, whereas the other known constituents including iridoids, phenol glycosides and flavonoids were previously isolated fr ...
DOI:
10.1016/j.phytol.2022.04.005

76. Bran-Enriched Milled Durum Wheat Fractions Obtained Using Innovative Micronization and Air-Classification Pilot Plants

Author:
Alessandro Cammerata; Francesco Sestili; Barbara Laddomada; Gabriella Aureli
Source:
Foods 2021 v.10 no.8 pp. -
ISSN:
2304-8158
Subject:
ash content; bran; durum wheat; health promotion; human health; lignans; particle size; plant estrogens
Abstract:
... Dietary guidelines recommend the consumption of unprocessed, or minimally processed, wheat foods because they are richer in health-promoting components (i.e., minerals, vitamins, lignans, phytoestrogens, and phenolic compounds) compared to traditionally refined products. The design and implementation of technological solutions applied to the milling process are becoming a key requirement to obtain ...
DOI:
10.3390/foods10081796

77. Chemical and Biological Evaluation of the Oil and Seedcake from Seeds of a Greek Cardoon Cultivar as Potential Functional Vegetable Oil. Comparison with Sesame, Flaxseed and Extra Virgin Olive Oils

Author:
Elisavet-Foteini Varvouni; Konstantia Graikou; Olga Gortzi; Antigoni Cheilari; Nektarios Aligiannis; Ioanna Chinou
Source:
Foods 2021 v.10 no.11 pp. -
ISSN:
2304-8158
Subject:
Cynara cardunculus; agricultural wastes; antioxidants; biological assessment; cardoons; cultivars; fatty acid composition; gas chromatography-mass spectrometry; health promotion; lignans; linseed; nutritive value; oilseed cakes; seed oils; solvents; sterols; therapeutics; vegetable oil; Mediterranean region
Abstract:
... Cynara cardunculus L. is a plant of the Mediterranean basin, known since antiquity as a food and for its therapeutic properties. The needs of the 21st century for the utilization of agricultural waste has led to the study of the seed oil of a Greek cultivar of Cynaracardunculus (GCCC) as potential nutritional oil, as large amounts of cardoon seeds are discarded. The sterol and fatty acid profile o ...
DOI:
10.3390/foods10112665

78. Chemical compositions, pharmacological activities, quality control studies of Erycibes plants, and the development of their substitutes

Author:
Yu Peng; Hongxun Tao; Yuanyuan Yang; Yuanqing Gao; Hui Ren; Jing Hu; Zhiyong Chen; Ye Li
Source:
Phytotherapy research 2021 v.35 no.8 pp. 4049-4074
ISSN:
0951-418X
Subject:
Convolvulaceae; analgesics; fever; flavonoids; hepatitis; lignans; liver; markets; medicinal plants; phytotherapy; quality control; quinic acid; research; rheumatoid arthritis; scopoletin; China; Thailand
Abstract:
... Erycibes are members of the Convolvulaceae family, including more than 10 species worldwide that are distributed in tropical Asia. Some Erycibes species have long been used as traditional remedies for rheumatoid arthritis, fever, hepatitis, and liver injury in China and Thailand. A total of 152 compounds from Erycibes plants have been isolated and identified, categorized as flavonoids, coumarins, ...
DOI:
10.1002/ptr.7070

79. Chemical constituents and aldose reductase inhibitory activities of Betula alba bark and leaves

Author:
Tomoki Iguchi; Minpei Kuroda; Nanami Akiyama; Mariko Hashimoto; Yoshihiro Mimaki
Source:
Natural product research 2022 v.36 no.4 pp. 1004-1008
ISSN:
1478-6427
Subject:
Betula pubescens var. pubescens; aldehyde reductase; bark; flavanones; glucosides; lignans; methyl salicylate; monoterpenoids; research; spectral analysis; triterpenoids
Abstract:
... Systematic phytochemical investigation of the bark and leaves of Betula alba was independently conducted. A new cyclic diarylheptanoid glucoside (1), five diarylheptanoids (2–6), a phenylethanoid (7), a methyl salicylate glycoside (8), a dihydrobenzofuran glucoside (9), an arylbutanoid glycoside (10), two lignan glycosides (11 and 12), a flavanone glucoside (13), and a triterpene (14) were isolate ...
DOI:
10.1080/14786419.2020.1839455

80. Chemical constituents from Semiliquidambar chingii and their chemotaxonomic significance

Author:
Jingyi Zhang; Kumaravel Kaliaperumal; Ziyue Liu; Jun Zhang
Source:
Biochemical systematics and ecology 2022 v.100 pp. 104360
ISSN:
0305-1978
Subject:
Altingia; Liquidambar; chemotaxonomy; coniferyl alcohol; ecology; ellagic acid; flavonoids; glycosides; hybrids; lignans; resveratrol; shikimic acid; spectral analysis; triterpenoids
Abstract:
... The present study investigated the phytochemical constituents of Semiliquidambar chingii for the first time, resulting in the isolation and characterization of nineteen compounds which were categorized into eight groups as resveratrol derivatives (1–4), triterpenoids (5–10), flavonoids (11–13), phenolic glycosides (14–15), lignan (16), ellagic acid derivative (17), coniferyl alcohol derivative (18 ...
DOI:
10.1016/j.bse.2021.104360

81. Chemical constituents from the aerial parts of Achillea alpina and their chemotaxonomic significance

Author:
Xiuwei Li; Xia Wu; Qiang Guo; Changli Liu; Hucheng Yue; Jiayi Tian; Zongyang Liu; Meng Xiao; Ang Li; Zhongqi Ning; Ke Zan; Xiaoqing Chen
Source:
Biochemical systematics and ecology 2022 v.101 pp. 104381
ISSN:
0305-1978
Subject:
Achillea; chemotaxonomy; ecology; lignans; phytochemicals; sesquiterpenoids; spectral analysis
Abstract:
... Phytochemical investigation of the aerial parts of Achillea alpina led to the isolation of sixteen compounds, including six sesquiterpenes (1-6), two polyacetylenic alcohols (7-8), three lignans (9-11), and five fatty acids (12-16). Their structures were identified by spectroscopic analysis of UV, IR, MS and NMR, and in comparison with the those reported data in the references. Among them, five co ...
DOI:
10.1016/j.bse.2022.104381

82. Chemical constituents from the fruits of Vitex rotundifolia and their chemotaxonomic significance

Author:
Yong-Ming Luo; Rui-Zeng Zhang; Fang-You Chen
Source:
Biochemical systematics and ecology 2022 v.103 pp. 104440
ISSN:
0305-1978
Subject:
Vitex rotundifolia; alkaloids; chemotaxonomy; diterpenoids; ecology; iridoids; lignans; spectral analysis; xanthones
Abstract:
... Chemical investigation on the fruits of Vitex rotundifolia Linnaeus f. Afforded 19 compounds, including three diterpenoids (1-3), two iridoids (4 and 5), three xanthones (6–8), an alkaloid (9), seven lignans (10–16), and three sesquilignans (17–19). The structures of these compounds were established via spectroscopic analysis and comparison of their NMR data with the literature. Compounds 1, 6–9, ...
DOI:
10.1016/j.bse.2022.104440

83. Chemical constituents from the leaves of Caesalpinia bonduc (L.) Roxb. and their chemotaxonomic significance

Author:
Le Thi Huyen; Vu Hoang Son; Truong Thi Viet Hoa; Luong Thi My Hanh; Seo Yohan; Park SeonJu; Nguyen Xuan Nhiem; Dan Thi Thuy Hang; Phan Van Kiem; Bui Huu Tai
Source:
Biochemical systematics and ecology 2022 v.100 pp. 104376
ISSN:
0305-1978
Subject:
Caesalpinia bonduc; chemotaxonomy; ecology; flavonoids; lignans; spectral analysis
Abstract:
... Caesalpinia bonduc (L.) Roxb. is an important herb in Ayurvedic medicines. In this study, five lignans (1–5), two phloroglucinols (6–7), five flavonoids (8–12) and four phenolics (13–16) were identified from the leaves of C. bonduc by comparison with spectroscopic data published in the literature. To the best of our knowledge, all of these identified phytochemicals were reported for the first time ...
DOI:
10.1016/j.bse.2021.104376

84. Chemical constituents from the roots of Cichorium glandulosum Boiss. et Huet (Asteraceae)

Author:
Ru Wang; Guijuan Zheng; Ting Dang; Pengfei Jin; Jia Yao; Linjie Su; Guangmin Yao; Dongmei Qin
Source:
Biochemical systematics and ecology 2021 v.96 pp. 104261
ISSN:
0305-1978
Subject:
Cichorium glandulosum; chemotaxonomy; ecology; isoquercitrin; lignans; myricetin; sesquiterpenoid lactones; spectral analysis
Abstract:
... A phytochemical investigation of the roots extract of Cichorium glandulosum led to the isolation and characterization of fourteen compounds, including five sesquiterpene lactones (1–5), five flavonoids (6–10), and four lignans (11–14). Their structures were determined by spectroscopic data analysis and comparison with the literatures. This is the first report of the crystal data of lactucopicrin ( ...
DOI:
10.1016/j.bse.2021.104261

85. Chemical constituents of Bulbophyllum wendlandianum (Kraenzl.) Dammer and their chemotaxonomic significance

Author:
Jia-Duo Yu; Ya-Ping Chen; Ya-Ting Shao; Xiao-Rong Zhou; Xia Zhao; Yu-Peng Li
Source:
Biochemical systematics and ecology 2021 v.96 pp. 104264
ISSN:
0305-1978
Subject:
Bulbophyllum; acetates; chemotaxonomy; ecology; ergosterol; ethyl ether; hydroquinone; hydroxybenzaldehyde; lignans; phenanthrenes; spectroscopy; stigmasterol; sulfoxides
Abstract:
... Phytochemical investigation of Bulbophyllum wendlandianum (Kraenzl.) Dammer led to the isolation of twenty-three compounds 1–23 (flavanthrinin 1, coelonin 2, lusianthridin 3, densiflorol B 4, plicatol B 5, batatasin-lll 6, gigantol 7, 5-hydroxy-3,3′-dimethoxy-2-(p-hydroxybenzyl) bibenzyl 8, 2,2-dimethyl-5-hydroxy-6-carboxy-7-(2-phenylethyl) 9, tristin 10, p-hydroxybenzyl ethyl ether 11, p-hydroxyb ...
DOI:
10.1016/j.bse.2021.104264

86. Chemical constituents of Peperomia tetraphylla (Forst. F.) Hooker et Arnott

Author:
Lu Wang; Shuang Wang; Qian Yao; Baolin Wang; Weidong Duan; Honglei Zhou; Kun Duan
Source:
Biochemical systematics and ecology 2021 v.99 pp. 104342
ISSN:
0305-1978
Subject:
Peperomia; chemotaxonomy; ecology; flavonoids; lignans; sitosterols
Abstract:
... Sixteen compounds were isolated from the whole herbs of Peperomia tetraphylla (Forst. F.) Hooker et Arnott by phytochemical methods, including eight flavonoids (1–3, 6, 7, 14–16), three lignans (8–10), three beta sitosterols (4, 5, 11), and two phenolic acids (12, 13). Their structures were identified by the analysis of NMR and MS, as well as the comparisons to the reported data. Among them, 2″-O- ...
DOI:
10.1016/j.bse.2021.104342

87. Chemical profiling and multicomponents quantitative analysis of Panzerina lanata by ultra‐fast liquid chromatography with tandem mass spectrometry

Author:
Yingying Mi; Wei Zheng; Xiangpei Zhao; Xun Zhang; Kang Yang; Gangyi Shen; Weizhi Liu; Wenrui Li; Baiping Ma; Dan Zhu
Source:
Journal of separation science 2021 v.44 no.13 pp. 2524-2535
ISSN:
1615-9306
Subject:
Oriental traditional medicine; bioactive properties; flavonoids; lignans; quantitative analysis; separation; tandem mass spectrometry; ultrafast liquid chromatography
Abstract:
... Panzerina lanata is a Chinese medicine with the bioactivity of detumescence and detoxification. In this study, novel qualitative and quantitative methods were established by ultra‐high performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry and ultra‐high‐performance liquid chromatography‐triple quadrupole linear ion trap mass spectrometry, respectively. As a result, 20 compo ...
DOI:
10.1002/jssc.202000944

88. Chemical profiling of Justicia vahlii Roth. (Acanthaceae) using UPLC-QTOF-MS and GC-MS analysis and evaluation of acute oral toxicity, antineuropathic and antioxidant activities

Author:
Abdul Basit; Saeed Ahmad; Kashif ur Rehman Khan; Abid Naeem; Muhammad Usman; Imtiaz Ahmed; Muhammad Nadeem Shahzad
Source:
Journal of ethnopharmacology 2022 v.287 pp. 114942
ISSN:
0378-8741
Subject:
2,2-diphenyl-1-picrylhydrazyl; Artemia; Justicia; acetic acid; acute oral toxicity; animal models; antioxidant activity; antioxidants; bioactive compounds; catalase; chemical constituents of plants; coumarins; death; flavonoids; glutathione; inflammation; interleukin-1beta; lignans; maceration; mortality; necrosis; nerve tissue; pain; secondary metabolites; tail; toxicity testing; traditional medicine
Abstract:
... Justicia vahlii Roth. (Acanthaceae), also called as kodasoori and bhekkar is an annual therophyte erect or decumbent herb used traditionally in toothache, skin diseases (itching, topical inflammation) and for the treatment of various respiratory disorders.The current study aimed at exploring pain cessation potential of J. vahlii Roth. via murine model of neuropathic pain and its phytochemical, tox ...
DOI:
10.1016/j.jep.2021.114942

89. Chemical profiling, quantitation, and bioactivities of Du-Zhong tea

Author:
Xiqing Shi; Shengbo Luo; Kan Zhong; Xinhua Hu; Zijia Zhang
Source:
Food chemistry 2022 v.394 pp. 133552
ISSN:
0308-8146
Subject:
Eucommia ulmoides; antioxidants; beverages; carboxylic ester hydrolases; flavonoids; food chemistry; iridoids; lignans; phenylpropanoids; tea
Abstract:
... Du-Zhong tea is a health beverage produced from Eucommia ulmoides leaves (EUL) as raw materials using traditional tea processing and Chinese herbal pieces processing methods. To evaluate the differences between tender leaves and mature leaves of Du-Zhong tea, UPLC-Q-TOF MS was used to analyze the constituents in EUL collected in April and August. A total of 52 compounds, including iridoids, phenyl ...
DOI:
10.1016/j.foodchem.2022.133552

90. Chemo-profiling of some Turkish Galanthus L. (Amaryllidaceae) species and their anticholinesterase activity

Author:
Buket Bozkurt; Gulen Irem Kaya; Mustafa Ali Onur; Nehir Unver-Somer
Source:
South African journal of botany 2021 v.136 pp. 65-69
ISSN:
0254-6299
Subject:
Alzheimer disease; Galanthus; acetylcholinesterase; bioactive properties; bulbs; chemical composition; chemical structure; cholinesterase; cholinesterase inhibitors; indigenous species; isoquinoline alkaloids; lignans; ornamental value; plant extracts; research
Abstract:
... Amaryllidaceae family, consisting of economically important plants with ornamental value, is very well-known for its isoquinoline alkaloids with variable biological activities and chemical structures. Among these alkaloids, an effective acetylcholinesterase inhibitor galanthamine, is prescribed widely in the treatment of Alzheimer's disease. Plants of the Amaryllidaceae family are therefore, subje ...
DOI:
10.1016/j.sajb.2020.09.012

91. Chemometric analysis applied to a chemophenetics approach in Simaroubaceae family: The relevance of alkaloids and quassinoids

Author:
Paula Mendonça Leite; Rachel Oliveira Castilho
Source:
Biochemical systematics and ecology 2021 v.94 pp. 104207
ISSN:
0305-1978
Subject:
Ailanthus; Brucea; Eurycoma; Hannoa; Picrasma; Quassia; Rutaceae; Simaba; Simarouba; chemometrics; chemotaxonomy; coumarins; ecology; flavonoids; lignans; quinones; triterpenoids; tryptophan
Abstract:
... Simaroubaceae family belongs to the order Sapindales, which in turn is part of Eurosides II (APG IV). It consists of 23 genera: Ailanthus; Amaroria; Brucea; Castela; Eurycoma; Gymnostemon; Hannoa; Holacantha; Homalolepsis; Iridosma; Laumoniera; Leitneria; Nothospondias; Odyendeya; Perriera; Picrasma; Picrolemma; Pierreodendron; Quassia; Samadera; Simaba; Simarouba; Soulamea. Over the years, the cl ...
DOI:
10.1016/j.bse.2020.104207

92. Chevalierinol A and B, two new neolignan sesquiterpenoids from Magnolia chevalieri

Author:
Pham Thi Ninh; Chu Thi Thu Ha; Tran Huy Thai; Nguyen Phuong Hanh; Nguyen Sinh Khang; Nguyen Thi Dung; Ly Thi Thu Hoai; Tran Van Chien; Tran Van Loc; Vo Thi Quynh Nhu; Nguyen The Anh; Trieu Quy Hung; Tran Van Sung; Ho Ngoc Anh; Tran Thi Phuong Thao
Source:
Natural product research 2021 v.35 no.21 pp. 3745-3751
ISSN:
1478-6427
Subject:
Magnolia; ethyl acetate; lignans; lipopolysaccharides; macrophages; nitric oxide; research; sesquiterpenoids; spectral analysis
Abstract:
... Two new neolignan sesquiterpenoids, chevalierinol A (1) and chevalierinol B (2), were isolated from the ethyl acetate extract of Magnolia chevalieri leaves, together with twelve known compounds (3–14). Their structures were elucidated by analysis of spectroscopic data including 1D, 2D and mass spectra and compared with the reported data. Compounds 1, 3, 4, 6, 7, 10 were evaluated for their inhibit ...
DOI:
10.1080/14786419.2020.1736061

93. Cistanche deserticola polysaccharides extracted from Cistanche deserticola Y.C. Ma promote the differentiation of mouse female germline stem cells in vitro

Author:
Yikai Qiu; Yanping Zhang; Hehe Ren; Yingxin Zhang; Xinrui Liu; Jing Pu; Jianqiang Yu; Xiaoli Yu; Xiuying Pei
Source:
Journal of ethnopharmacology 2022 pp. 115495
ISSN:
0378-8741
Subject:
Cistanche deserticola; Oriental traditional medicine; Western blotting; bone morphogenetic proteins; cell differentiation; cell proliferation; cell structures; cell viability; culture media; females; fluorescent antibody technique; gene expression; gene expression regulation; genes; glycosides; iridoids; lignans; mice; oocytes; phenylethyl alcohol; polysaccharides; quantitative polymerase chain reaction; retinoic acid; sequence analysis; signal transduction; synaptonemal complex; China
Abstract:
... Traditional Chinese herbal medicine Cistanche deserticola Y.C. Ma has been recorded and treatment for infertility and impotence since ancient times, which is widely distributed in northwest China, and is mainly composed of phenylethanol glycosides, iridoids, lignans, polysaccharides, alkaloids, etc. C. deserticola polysaccharides (CDPs) is one of its main active ingredients, studies of its effect ...
DOI:
10.1016/j.jep.2022.115495

94. Comprehensive characterization and identification of chemical constituents in Yangwei decoction using ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry

Author:
Shuaishuai Fan; Baolin Li; Yurou Tian; Wei Feng; Liying Niu
Source:
Journal of separation science 2022 v.45 no.5 pp. 1006-1019
ISSN:
1615-9306
Subject:
Oriental traditional medicine; cold; electrospray ionization mass spectrometry; flavonoids; glycosides; lactones; lignans; pharmacology; separation; tandem mass spectrometry; triterpenoids; ultra-performance liquid chromatography
Abstract:
... Yangwei decoction, a classical traditional Chinese medicine prescription, has been widely used to treat exogenous cold and internal injury with damp stagnation for many centuries. However, its systematic chemical profiling remains ambiguous, which has hampered the interpretation of pharmacology and the mechanism of its formula. In the present study, ultra‐performance liquid chromatography coupled ...
DOI:
10.1002/jssc.202100723

95. Computationally approached inhibition potential of Tinospora cordifolia towards COVID-19 targets

Author:
Sushovan Jena; Punnagai Munusami; Balamurali MM; Kaushik Chanda
Source:
Virusdisease 2021 v.32 no.1 pp. 65-77
ISSN:
2347-3584
Subject:
COVID-19 infection; Severe acute respiratory syndrome coronavirus 2; Tinospora cordifolia; density functional theory; geometry; humans; lignans; morbidity; mortality; terpenoids; therapeutics; vaccines
Abstract:
... The recent emergence of novel coronavirus (SARS-CoV-2) has been a major threat to human society, as the challenge of finding suitable drug or vaccine is not met till date. With increasing morbidity and mortality, the need for novel drug candidates is under great demand. The investigations are progressing towards COVID-19 therapeutics. Among the various strategies employed, the use of repurposed dr ...
DOI:
10.1007/s13337-021-00666-7

96. Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

Author:
Nai‐Qian Dong; Hong‐Xuan Lin
Source:
Journal of integrative plant biology 2021 v.63 no.1 pp. 180-209
ISSN:
1672-9072
Subject:
amides; coumaric acids; epigenetics; evolution; flavonoids; freshwater; homeostasis; lignans; lignin; metabolism; metabolites; plant development; plant hormones; sporopollenin; transcription (genetics)
Abstract:
... Phenylpropanoid metabolism is one of the most important metabolisms in plants, yielding more than 8,000 metabolites contributing to plant development and plant–environment interplay. Phenylpropanoid metabolism materialized during the evolution of early freshwater algae that were initiating terrestrialization and land plants have evolved multiple branches of this pathway, which give rise to metabol ...
DOI:
10.1111/jipb.13054

97. Copper nanoclusters-based fluorescent sensor array to identify metal ions and dissolved organic matter

Author:
Jinming Xu; Huangmei Zhou; Yixue Zhang; Yu Zhao; Hao Yuan; Xiaoxiao He; Ying Wu; Sanjun Zhang
Source:
Journal of hazardous materials 2022 v.428 pp. 128158
ISSN:
0304-3894
Subject:
discriminant analysis; fluorescence; glutathione; histidine; lignans; polyethyleneimine; principal component analysis; rapid methods; riparian areas; seawater; tap water; water pollution; water quality
Abstract:
... In recent years, the prevention and control of water pollution has received extensive attention. There is a need to develop simple and effective strategies for the rapid detection of metal ions and dissolved organic matter (DOM) in order to improve water quality. To this end, the first copper nanoclusters (CuNCs)-based fluorescent sensor array was done to identify 12 metal ions (Pb²⁺, Fe³⁺, Cu²⁺, ...
DOI:
10.1016/j.jhazmat.2021.128158

98. Correlation between phytocompounds and pharmacological activities of Boerhavia diffusa Linn with traditional-ethnopharmacological insights

Author:
Praveen Kumar Gaur; Sameer Rastogi; Kanak Lata
Source:
Phytomedicine plus 2022 v.2 no.2 pp. 100260
ISSN:
2667-0313
Subject:
Ayurvedic medicine; Boerhavia diffusa; antioxidants; cardiovascular diseases; ecdysteroids; edema; humans; inflammation; kidneys; lignans; nephroprotective effect; nutrient content; polyphenols; rotenoids; wastelands; wet season; Africa; Asia; North America; South America
Abstract:
... : The human body is almost 70% water and fluid imbalance has been a classic symptom of severe underlying conditions, i.e., hepatic disorders, kidney disorders, cardiovascular disease and inflammation. Boerhavia diffusa Linn. is a pantropical herb used in traditional medicine systems worldwide for inflammation, liver-kidney disorders, skin problems, etc. Ethnopharmacological reports of B. diffusa c ...
DOI:
10.1016/j.phyplu.2022.100260

99. Corrigendum to “A new phenylethyl glycoside and a new dibenzocyclooctadiene lignan from the leaves of Kadsura coccinea (Lem.) A. C. Smith” [Phytochem. Lett. 45 (2021) 57–62]

Author:
Le Huyen Tram; Tran Thu Huong; Le Thi Thuy; Nguyen Van Thong; Nguyen Tuan Anh; Nguyen Hoang Minh; Tran Thi Minh; Nguyen Thi Hong Phuong; Tran Thu Ha; Nguyen Hai Dang; Duc Dat Le; Pham Phuoc Dien; Mina Lee
Source:
Phytochemistry letters 2022 v.48 pp. 132-137
ISSN:
1874-3900
Subject:
Kadsura coccinea; circular dichroism spectroscopy; glycosides; hydrolysis; lignans; lipopolysaccharides; mass spectrometry; nitric oxide; nuclear magnetic resonance spectroscopy; plant biochemistry
Abstract:
... A new phenylethyl glycoside (1), (S)-1-phenylethyl-6-α-L-arabinopyranosyl-β-D-glucopyranoside), and a new dibenzocyclooctadiene lignan (7), Kasuracin A, together with seven known compounds, were isolated and identified from the leaves of Kadsura coccinea. Their structures were determined by analysis of multinuclear and multidimensional nuclear magnetic resonance (NMR), circular dichroism (CD), mas ...
DOI:
10.1016/j.phytol.2021.09.013

100. Cough Inhibition Activity of Schisandra chinensis in Guinea Pigs

Author:
Shan Zhong; Li-Ping Bai; Xiao-Dong Liu; Die-Yi Cai; Lee-Fong Yau; Chu-Qin Huang; Jia-Qi Zhang; Ke-Fang Lai; Nan-Shan Zhong
Source:
Journal of medicinal food 2021 v.24 no.4 pp. 348-357
ISSN:
1557-7600
Subject:
Oriental traditional medicine; Schisandra chinensis; animal models; antioxidants; butanol; cigarettes; citric acid; cough; ethanol; ethyl acetate; functional foods; guinea pigs; hypersensitivity; lignans; liquid chromatography; mass spectrometry; petroleum; smoke; triterpenoids; Guinea
Abstract:
... Chronic cough is very common in respiratory clinics, and no effective drugs are available. Schisandra chinensis (Turcz.) Baill. (S. chinensis), an important traditional Chinese medicine, has been extensively prescribed for patients with a persistent cough. Preliminary research indicated that 95% ethanol extracts (EE) of S. chinensis showed remarkable antitussive activity in guinea pigs exposed to ...
DOI:
10.1089/jmf.2020.4824