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- Lim, Hyung-Woo, et al. Show all 9 Authors
- Food and chemical toxicology 2014 v.72 pp. 265-272
- Acorus gramineus; anti-inflammatory activity; dose response; ethanol; eugenol; inducible nitric oxide synthase; lipopolysaccharides; messenger RNA; mitogen-activated protein kinase; neuroglia; nitric oxide; phytopharmaceuticals; prostaglandin synthase; toxicology; transcription factor NF-kappa B
- ... Acorus species contains diverse pharmacologically active phytochemicals including α-asarone, β-asarone, and eugenol. We determined if β-asarone isolated from Acorus gramineus (AG) Solander would be efficacious in protecting BV-2 microglia cells from lipopolysaccharide (LPS)-induced stress signaling. BV-2 microglial cells were pretreated with an AG ethanol extract (1, 10, and 100μg/mL) or β-asarone ...
- Lim, Hyung-Woo, et al. Show all 8 Authors
- Journal of ethnopharmacology 2012 v.139 no.2 pp. 549-557
- Gastrodia elata; alcohols; bioactive properties; cytokines; headache; lipopolysaccharides; mitogen-activated protein kinase; neuroglia
- ... ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Blume (Orchidaceae, GE) a traditional plant in Oriental countries is known for its enormous benefits to treat headaches, dizziness, vertigo and convulsive illnesses. In the present study, the ethnopharmacological role of GE in neuroinflammation mediated by activated microglia and the mechanisms underlying were reported. MATERIALS AND METHODS: BV-2 mi ...