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- Cho, Samuel S.; Pincus, David L.; Thirumalai, D.
- Proceedings of the National Academy of Sciences of the United States of America 2009 v.106 no.41 pp. 17349-17354
- specific heat, etc ; RNA; RNA folding; energy; genome; humans; melting; melting point; models; telomerase; temperature; Show all 11 Subjects
- ... Understanding how RNA molecules navigate their rugged folding landscapes holds the key to describing their roles in a variety of cellular functions. To dissect RNA folding at the molecular level, we performed simulations of three pseudoknots (MMTV and SRV-1 from viral genomes and the hTR pseudoknot from human telomerase) using coarse-grained models. The melting temperatures from the specific heat ...
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