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1. Differential induction of antibacterial transcripts in Drosophila susceptible and resistant to parasitism by Leptopilina boulardi

Author:
Coustau, C.; Carton, Y.; Nappi, A.; Shotkoski, F.; Ffrench-Constant, R.
Source:
Insect molecular biology 1996 v.5 no.3 pp. 167-172
ISSN:
0962-1075
Subject:
immune response,   etc   ; antibacterial properties; parasitoids; messenger RNA; Drosophila melanogaster; structural genes; peptides; encapsulation; gene expression; Leptopilina boulardi; induced resistance; pest resistance; Escherichia coli;     Show all 13 Subjects
Abstract:
... Two well-described elements of the immune response of insects include encapsulation of metazoan parasites (blood-cell-mediated) and the production of antibacterial peptides (humoral and/or cellular). However, the possible functional interrelationship between cellular encapsulation and antibacterial responses, and the extent to which the two components may be co-regulated, are poorly understood. We ...
DOI:
10.1111/j.1365-2583.1996.tb00050.x
PubMed:
8799734

2. Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA

Author:
Richman, A.M.; Bulet, P.; Hetru, C.; Barillas-Mury, C.; Hoffmann, J.A.; Kafatos, F.C.
Source:
Insect molecular biology 1996 v.5 no.3 pp. 203-210
ISSN:
0962-1075
Subject:
immune response,   etc   ; polypeptides; messenger RNA; disease vectors; structural genes; complementary DNA; nucleotides; amino acid sequences; gene expression; Anopheles gambiae; nucleotide sequences; malaria; bacteria; antibacterial properties;     Show all 14 Subjects
Abstract:
... Larvae of the mosquito vector of human malaria, Anopheles gambiae, were inoculated with bacteria and extracts were biochemically fractionated by reverse-phase HPLC. Multiple induced polypeptides and activities were observed following bacterial infection, including a member of the insect defensin family of antibacterial proteins. A cDNA encoding An. gambiae preprodefensin was isolated using PCR pri ...
DOI:
10.1111/j.1365-2583.1996.tb00055.x
PubMed:
8799739

3. Protein purification and nucleotide sequence of a lysozyme from the bacteria-induced larvae of the fall webworm, Hyphantria cunea

Author:
Park, H.Y.; Park, S.S.; Shin, S.W.; Park, D.S.; Kim, M.G.; Oh, H.W.; Joo, C.K.
Source:
Archives of insect biochemistry and physiology 1997 v.35 no.3 pp. 335-345
ISSN:
0739-4462
Subject:
immune response,   etc   ; lysozyme; messenger RNA; Hyphantria cunea; complementary DNA; structural genes; phylogeny; amino acid sequences; gene expression; nucleotide sequences; enzyme activity; Escherichia coli;     Show all 12 Subjects
Abstract:
... A protein with lytic activity against Micrococcus luteus was purified from the hemolymph of the fall webworm, Hyphantria cunea, larvae challenged with live E. coli. A bacteriolytic protein of about 14,000 daltons in mass was purified by cation exchange chromatography and reverse-phased HPLC. The optimum pH and optimum temperature range for activity were around pH 6.2 and 50 degrees C, respectively ...
DOI:
10.1002/(SICI)1520-6327(199705)35:3<335::AID-ARCH7>3.0.CO;2-S
PubMed:
9177137

4. Molecular cloning and chromosomal localization of a prophenoloxidase cDNA from the malaria vector Anopheles gambiae

Author:
Lee, W.J.; Ahmed, A.; Della Torre, A.; Kobayashi, A.; Ashida, M.; Brey, P.T.
Source:
Insect molecular biology 1998 v.7 no.1 pp. 41-50
ISSN:
0962-1075
Subject:
immune response,   etc   ; Anopheles gambiae; monophenol monooxygenase; zymogens; structural genes; complementary DNA; nucleotide sequences; amino acid sequences; chromosome mapping; gene expression; messenger RNA; developmental stages; sequence homology;     Show all 13 Subjects
Abstract:
... A cDNA clone for prophenoloxidase was isolated from the most important human malaria vector, Anopheles gambiae. The clone encoded a polypeptide of 79341 Da that contains the two copper binding domains common to all invertebrate prophenoloxidases and haemocyanins. Expression of the prophenoloxidase gene was detected throughout all life stages from egg to imago in two strains of A. gambiae; however, ...
DOI:
10.1046/j.1365-2583.1998.71047.x
PubMed:
9459428

5. Molecular cloning, characterization and tissue expression of prophenoloxidase cDNA from the mosquito Armigeres subalbatus inoculated with Dirofilaria immitis microfilariae

Author:
Cho, W.L.; Liu, H.S.; Lee, C.H.; Kuo, C.C.; Chang, T.Y.; Liu, C.T.; Chen, C.C.
Source:
Insect molecular biology 1998 v.7 no.1 pp. 31-40
ISSN:
0962-1075
Subject:
immune response,   etc   ; Armigeres subalbatus; Dirofilaria immitis; monophenol monooxygenase; zymogens; structural genes; complementary DNA; nucleotide sequences; amino acid sequences; gene expression; messenger RNA; hemocytes; entomopathogenic nematodes; sequence homology;     Show all 14 Subjects
Abstract:
... A cDNA encoding mosquito Armigeres subalbatus prophenol oxidase (As-pro-PO) was obtained by rapid chain reaction (RACE-PCR) after Dirofilaria immitis inoculation. The 2205 bp As-pro-PO cDNA contains a 32 bp 5'-noncoding region, a 2055 bp open reading frame (685 amino acids), and a 118 bp 3-noncoding region. Hydrophobic signal peptide for the endoplasmic reticulum targeting is not found in the NH2- ...
DOI:
10.1046/j.1365-2583.1998.71049.x
PubMed:
9459427

6. Polydnavirus-mediated inhibition of lysozyme gene expression and the antibacterial response

Author:
Shelby, K.S.; Cui, L.; Webb, B.A.
Source:
Insect molecular biology 1998 v.7 no.3 pp. 265-272
ISSN:
0962-1075
Subject:
immune response,   etc   ; lysozyme; parasitism; messenger RNA; parasitoids; complementary DNA; Polydnaviridae; amino acid sequences; gene expression; nucleotide sequences; Heliothis virescens; Campoletis sonorensis; enzyme activity;     Show all 13 Subjects
Abstract:
... Parasitism of lepidopteran host larvae by hymenopteran parasitoids impairs the cellular immune response via expression of polydnavirus genes. Encapsulation of parasitoid eggs is thereby prevented. Parasitized insects are susceptible to opportunistic infections, suggesting that additional components of the immune system are affected. Insects normally respond to infection by inducing the synthesis o ...
DOI:
10.1111/j.1365-2583.1998.00071.x
PubMed:
9662476

7. Plasmatocyte spreading peptide does not induce Microplitis demolitor polydnavirus-infected plasmatocytes to spread on foreign surfaces

Author:
Strand, M.R.; Clark, K.C.; Gardiner, E.M.M.
Source:
Archives of insect biochemistry and physiology 1999 v.40 no.1 pp. 41-52
ISSN:
0739-4462
Subject:
immune response,   etc   ; Pseudoplusia includens; Microplitis demolitor; parasitoids; parasitism; hemocytes; adhesion; encapsulation; peptides; Polydnaviridae; host-parasite relationships; messenger RNA; gene expression; fat body;     Show all 14 Subjects
Abstract:
... Capsule formation by the moth Pseudopulsia includens requires that plasmatocytes change from being nonadhesive cells in circulation to strongly adhesive cells capable of attaching to the foreign target and one another. This change in adhesive state is induced by Plasmatocyte Spreading Peptide (PSP1); a 23 amino acid peptide isolated from P. includens plasma. Plasmatocytes from hosts parasitized by ...
DOI:
10.1002/(SICI)1520-6327(1999)40:1<41::AID-ARCH5>3.0.CO;2-R
PubMed:
9987820

8. Characterization of a canine CD44 specific monoclonal antibody

Author:
Alldinger, S.; Baumgartner, W.; Kremmer, E.; Fonfara, S.
Source:
Journal of veterinary medicine 1999 v.46 no.1 pp. 19-32
ISSN:
0931-184X
Subject:
immune response,   etc   ; messenger RNA; central nervous system; monocytes; immunohistochemistry; molecular weight; dogs; macrophages; lymphocytes; monoclonal antibodies; histiocytosis; cell membranes; epithelium;     Show all 13 Subjects
DOI:
10.1046/j.1439-0442.1999.00184.x
PubMed:
10085764

9. Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae

Author:
Vizioli, J.; Bulet, P.; Charlet, M.; Lowenberger, C.; Blass, C.; Muller, H.M.; Dimopoulos, G.; Hoffmann, J.; Kafatos, F.C.; Richman, A.
Source:
Insect molecular biology 2000 v.9 no.1 pp. 75-84
ISSN:
0962-1075
Subject:
immune response,   etc   ; messenger RNA; structural genes; complementary DNA; amino acid sequences; gene expression; antimicrobial peptides; chromosome mapping; Anopheles gambiae; nucleotide sequences; synthetic peptides; antibacterial properties;     Show all 12 Subjects
DOI:
10.1046/j.1365-2583.2000.00164.x
PubMed:
10672074

10. Insect immunity: a genetic factor (hrtp) is essential for antibacterial peptide expression in Drosophila after infection by parasitoid wasps

Author:
Benassi, V.; Coustau, C.; Carton, Y.
Source:
Archives of insect biochemistry and physiology 2000 v.43 no.2 pp. 64-71
ISSN:
0739-4462
Subject:
immune response,   etc   ; Drosophila melanogaster; strains; Leptopilina boulardi; Leptopilina heterotoma; parasitoids; humoral immunity; peptides; antibacterial properties; gene expression; messenger RNA; encapsulation; transgenic animals; chromosomes; cell-mediated immunity; Asobara tabida;     Show all 16 Subjects
Abstract:
... We have used a parasitoid wasp Drosophila melanogaster system to investigate the relationship between the humoral and cellular immune responses in insects. Expression of the gene encoding diptericin, an antibacterial peptide in various D. melanogaster strains parasitized by several species of parasitoid wasps, was studied by Northern blot. These strains have the capacity to encapsulate parasitoid ...
DOI:
10.1002/(SICI)1520-6327(200002)43:2<64::AID-ARCH2>3.0.CO;2-I
PubMed:
10644970

11. Molecular characterization of a prophenoloxidase cDNA from the malaria mosquito Anopheles stephensi

Author:
Cui, L.; Luckhart, S.; Rosenberg, R.
Source:
Insect molecular biology 2000 v.9 no.2 pp. 127-137
ISSN:
0962-1075
Subject:
immune response,   etc   ; Anopheles stephensi; zymogens; monophenol monooxygenase; complementary DNA; nucleotide sequences; amino acid sequences; gene expression; messenger RNA; enzyme activity; Plasmodium berghei; encapsulation; disease vectors; malaria;     Show all 14 Subjects
DOI:
10.1046/j.1365-2583.2000.00169.x
PubMed:
10762420

12. Interferon-gamma is expressed in both gut and spleen during Eimeria tenella infection

Author:
Rothwell, L.; Muir, W.; Kaiser, P.
Source:
Avian pathology 2000 v.29 no.4 pp. 333-342
ISSN:
0307-9457
Subject:
immune response,   etc   ; chickens; Eimeria tenella; cecum; spleen; splenocytes; messenger RNA; coccidiosis; interferons;     Show all 9 Subjects
Abstract:
... The effect of primary infection and subsequent challenge with Eimeria tenella on interferon-gamma (IFN-gamma) production in the spleen and caeca of Light Sussex chickens was assessed. The ability of splenocytes to proliferate and produce IFN-gamma in response to mitogen stimulation ex vivo was determined. Differences in the kinetics of IFN-gamma production suggested that the spleens of infected bi ...
DOI:
10.1080/03079450050118467
PubMed:
19184823

13. Crustacean haemocytes and haematopoiesis

Author:
Johansson, M.W.; Keyser, P.; Sritunyalucksana, K.; Soderhall, K.
Source:
Aquaculture 2000 no.1/3 pp. 45-52
ISSN:
0044-8486
Subject:
immune response,   etc   ; Crustacea; hemocytes; defense mechanisms; phagocytosis; cytotoxicity; cytoplasm; immune system; protein synthesis; messenger RNA; nucleic acid hybridization;     Show all 11 Subjects
Abstract:
... Crustacean haemocytes play important roles in the host immune response including recognition, phagocytosis, melanization, cytotoxicity and cell-cell communication. Classification of the haemocyte types in decapod crustaceans is based mainly on the presence of cytoplasmic granules into hyaline cells, semigranular cells, and granular cells. Each cell type is active in defence reactions, for example; ...

14. Immune activation upregulates lysozyme gene expression in Aedes aegypti mosquito cell culture

Author:
Gao, Y.; Fallon, A.M.
Source:
Insect molecular biology 2000 v.9 no.6 pp. 553-558
ISSN:
0962-1075
Subject:
immune response,   etc   ; Aedes aegypti; lysozyme; complementary DNA; structural genes; nucleotide sequences; amino acid sequences; gene expression; messenger RNA; gene dosage; bacteria; cell lines; insect immunity;     Show all 13 Subjects
DOI:
10.1046/j.1365-2583.2000.00216.x
PubMed:
11122464

15. Wolbachia neither induces nor suppresses transcripts encoding antimicrobial peptides

Author:
Bourtzis, K.; Pettigrew, M.M.; O'Neill, S.L.
Source:
Insect molecular biology 2000 v.9 no.6 pp. 635-639
ISSN:
0962-1075
Subject:
immune response,   etc   ; Drosophila simulans; Aedes albopictus; Wolbachia pipientis; peptides; antimicrobial properties; genetic markers; nucleotide sequences; amino acid sequences; gene expression; messenger RNA; transcription (genetics); insect immunity;     Show all 13 Subjects
DOI:
10.1046/j.1365-2583.2000.00224.x
PubMed:
11122472

16. Resveratrol inhibits intestinal tumorigenesis and modulates host-defense-related gene expression in an animal model of human familial adenomatous polyposis

Author:
Schneider, Y.; Duranton, B.; Gosse, F.; Schleiffer, R.; Seiler, N.; Raul, F.
Source:
Nutrition and cancer 2001 v.39 no.1 pp. 102-107
ISSN:
0163-5581
Subject:
immune response,   etc   ; carcinogenesis; messenger RNA; ileum; experimental diets; mice; gene expression; jejunum; animal models; intestinal mucosa; genes; cell proliferation; cell cycle; antioxidants; colon;     Show all 15 Subjects
Abstract:
... We studied the effect of oral administration of resveratrol, a natural constituent of grapes, on tumorigenesis in Min mice. Min mice are congenic mice genetically predisposed to develop intestinal tumors as a result of a mutation of the Apc gene. Resveratrol (0.01% in the drinking water containing 0.4% ethanol) was administered for seven weeks to Min mice starting at five weeks of age. The control ...
DOI:
10.1207/S15327914nc391_14
PubMed:
11588890

17. Quantitative assessment of mast cells and expression of IgE protein and mRNA for IgE and interleukin 4 in the gastrointestinal tract of healthy dogs and dogs with inflammatory bowel disease

Author:
Locher, C.; Tipold, A.; Welle, M.; Busato, A.; Zurbriggen, A.; Griot-Wenk, M.E.
Source:
American journal of veterinary research 2001 v.62 no.2 pp. 211-216
ISSN:
0002-9645
Subject:
immune response,   etc   ; dogs; digestive system diseases; inflammation; mast cells; immunoglobulin E; messenger RNA; interleukin-4; digestive tract; lymph nodes;     Show all 10 Subjects
DOI:
10.2460/ajvr.2001.62.211
PubMed:
11212030

18. Effects of dietary polyunsaturated fatty acids on in vivo splenic cytokine mRNA expression in layer chicks immunized with Salmonella typhimurium lipopolysaccharides

Author:
Sijben, J.W.C.; Schrama, J.W.; Parmentier, H.K.; Poel, J.J. van der.; Klasing, K.C.
Source:
Poultry science 2001 v.80 no.8 pp. 1164-1170
ISSN:
0032-5791
Subject:
immune response,   etc   ; messenger RNA; protein synthesis; hens; lipopolysaccharides; dietary fat; interleukins; T-lymphocytes; Salmonella Typhimurium; polymerase chain reaction; gene expression; transforming growth factors; spleen; immunization; actin; polyunsaturated fatty acids; chicks; interferons;     Show all 18 Subjects
Abstract:
... Effects of dietary polyunsaturated fatty acids (PUFA) on immune responses in poultry have been reported. However, effects on the underlying mechanisms, such as the role of cytokines, have not been documented because the necessary tools were lacking. Recently, primer sets for chicken interleukin (IL)-1beta, IL-2, interferon-gamma (IFN-gamma), myelomonocytic growth factor (MGF), and transforming gro ...
DOI:
10.1093/ps/80.8.1164

19. Expression of defensin-like peptides in tick hemolymph and midgut in response to challenge with Borrelia burgdorferi, Escherichia coli and Bacillus subtilis

Author:
Sonenshine, D.E.; Ceraul, S.M.; Hynes, W.E.; Macaluso, K.R.; Azad, A.F.
Source:
Experimental & applied acarology 2002 v.28 no.1-4 pp. 127-134
ISSN:
0168-8162
Subject:
immune response,   etc   ; Dermacentor variabilis; ticks; hemolymph; midgut; antimicrobial peptides; Borrelia burgdorferi; Escherichia coli; Bacillus subtilis; bacterial infections; infection; gene induction; gene expression; messenger RNA; disease vectors;     Show all 15 Subjects

20. The application of nucleic acid vaccines in veterinary medicine

Author:
Dunham, Stephen P.
Source:
Research in veterinary science 2002 v.73 no.1 pp. 9-16
ISSN:
0034-5288
Subject:
immune response,   etc   ; DNA; antigens; domestic animals; immune system; messenger RNA; protein synthesis; proteins; recombinant vaccines; translation (genetics); vaccination; veterinary medicine;     Show all 12 Subjects
Abstract:
... Nucleic acid immunisation entails the delivery of DNA (or RNA) encoding a vaccine antigen to the recipient. The DNA is taken up by host cells and transcribed to mRNA, from which the vaccine proteins are then translated. The expressed proteins are recognised as foreign by the host immune system and elicit an immune response, which may have both cell-mediated and humoral components. DNA vaccines off ...
DOI:
10.1016/S0034-5288(02)00032-2
PubMed:
12208102

21. Effects of oligosaccharide on the faecal flora and non-specific immune system in elderly people

Author:
Guigoz, Y.; Rochat, F.; Perruisseau-Carrier, G.; Rochat, I.; Schiffrin, E.J.
Source:
Nutrition research 2002 v.22 no.1-2 pp. 13-25
ISSN:
0271-5317
Subject:
immune response,   etc   ; bacteria; elderly; feces; flora; fructooligosaccharides; granulocytes; interleukin-6; messenger RNA; monocytes; nursing homes; patients; people; phagocytosis; plate count;     Show all 15 Subjects
Abstract:
... Aims: The primary objectives was to confirm the bifidogenic effects of fructooligosaccharides in elderly subjects (increase equal or higher than 1 log endogenous bifidobacteria per gram of faeces), and to make an exploratory investigation on non-specific immune defense parameters, such as phagocytosis and changes in lymphocyte subpopulations, in relation to the increase in endogenous bifidobacteri ...

22. Expression and distribution of penaeidin antimicrobial peptides are regulated by haemocyte reactions in microbial challenged shrimp

Author:
Muñoz, Marcelo; Vandenbulcke, Franck; Saulnier, Denis; Bachère, Evelyne
Source:
European journal of biochemistry 2002 v.269 no.11 pp. 2678-2689
ISSN:
0014-2956
Subject:
immune response,   etc   ; Penaeidae; antimicrobial peptides; bacteria; blood circulation; hemocytes; messenger RNA; shrimp; tissues;     Show all 9 Subjects
Abstract:
... Penaeidins are a family of antimicrobial peptides constitutively produced and stored in the haemocytes of penaeid shrimp. In response to microbial stimulation, they are released into the blood circulation and they further attach to shrimp cuticle surfaces through a chitin‐binding property. In the present paper, we have analysed their expression, regulation and distribution in shrimp tissues in r ...
DOI:
10.1046/j.1432-1033.2002.02934.x

23. Altered expression of cellular genes in neutrophils of periparturient dairy cows

Author:
Madsen, Sally A.; Weber, Patty S.D.; Burton, Jeanne L.
Source:
Veterinary immunology and immunopathology 2002 v.86 no.3-4 pp. 159-175
ISSN:
0165-2427
Subject:
immune response,   etc   ; DNA-binding proteins; Northern blotting; animal health; blood serum; complementary DNA; cytochrome b; dairy cows; estradiol; gene expression; gene expression regulation; genes; mastitis; messenger RNA; metabolism; neutrophils; nucleic acid hybridization; nucleotide sequences; parturition; progesterone; radioimmunoassays; reverse transcriptase polymerase chain reaction; screening; sequence homology; steroid hormones; tricarboxylic acid cycle;     Show all 26 Subjects
Abstract:
... The periparturient dairy cow undergoes a plethora of physiological changes, including changes in the immune system that lead to profound effects on animal health. Of the immune cells affected at parturition, the neutrophil has been of particular interest due to its primary role in innate immune defense against mastitis. Immune functions of bovine neutrophils are known to be depressed around partur ...
DOI:
10.1016/S0165-2427(02)00020-X

24. Presence and regulation of the endocannabinoid system in human dendritic cells

Author:
Matias, Isabel; Pochard, Pierre; Orlando, Pierangelo; Salzet, Michel; Pestel, Joel; Di Marzo, Vincenzo
Source:
European journal of biochemistry 2002 v.269 no.15 pp. 3771-3778
ISSN:
0014-2956
Subject:
immune response,   etc   ; allergens; anti-inflammatory activity; basophils; cannabinoids; dendritic cells; enzymes; fatty acids; humans; hydrolysis; immunoblotting; lipopolysaccharides; liquid chromatography; lymphocytes; macrophages; mass spectrometry; messenger RNA; monocytes; receptors; reverse transcriptase polymerase chain reaction;     Show all 20 Subjects
Abstract:
... Cannabinoid receptors and their endogenous ligands, the endocannabinoids, have been detected in several blood immune cells, including monocytes/macrophages, basophils and lymphocytes. However, their presence in dendritic cells, which play a key role in the initiation and development of the immune response, has never been investigated. Here we have analyzed human dendritic cells for the presence of ...
DOI:
10.1046/j.1432-1033.2002.03078.x

25. A novel transcutaneous plasmid–dimethylsulfoxide delivery technique for avian nucleic acid immunization

Author:
Heckert, R.A.; Elankumaran,S.; Oshop, G.L.; Vakharia, V.N.
Source:
Veterinary immunology and immunopathology 2002 v.89 no.1-2 pp. 67-81
ISSN:
0165-2427
Subject:
immune response,   etc   ; chickens; green fluorescent protein; immunoglobulin M; messenger RNA; blood serum; vaccination; dimethyl sulfoxide; macrophages; mucosal immunity; plasmids; immunoglobulin A; Avian orthoavulavirus 1; bone marrow; tears; transfection; Infectious bursal disease virus; recombinant vaccines; reporter genes; virulence;     Show all 20 Subjects
Abstract:
... In this report, we show that dimethylsulfoxide (DMSO) enhances liposome-mediated transfection of nucleic acid in chicken macrophage cells and that this could be exploited for the transcutaneous delivery of naked DNA through the intact skin of chickens. We found that DMSO enhanced transfection efficiencies of lipofectamine and polyethyleneimine in HD-11 chicken macrophage cells. Based on this princ ...
DOI:
10.1016/S0165-2427(02)00186-1

26. Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjogren’s syndrome

Author:
Tovar, A.R.; Gomez, E.; Bourges, H.; Ortız, V.; Kraus, A.; Torres, N.
Source:
European journal of clinical nutrition 2002 v.56 no.11 pp. 1087-1093
ISSN:
0954-3007
Subject:
immune response,   etc   ; T-lymphocytes; aspartate transaminase; blood sampling; cross-over studies; erythrocytes; food intake; gene expression; interleukin-2; messenger RNA; nutrition assessment; patients; phytohemagglutinin; placebos; pyridoxine;     Show all 15 Subjects
Abstract:
... Background: There is evidence that pyridoxine deficiency may alter the immune response. It is not known whether a deficiency of this vitamin is evident in subjects with primary Sjogren’s syndrome (SS). Objective: We studied whether subjects with primary SS showed a biochemical deficiency of pyridoxine, and if it is associated with abnormal production of interleukin-2 from lymphocytes stimulated in ...
DOI:
10.1038/sj.ejcn.1601450

27. Immuno activation of lectin-conjugated praecoxin a on IL-6, IL-12 expression

Author:
Joo, Seong -Soo; Chang, Jae -Kwon; Park, Jeong -Hwan; Kang, Hee -Chul; Lee, Do -Ik
Source:
Archives of pharmacal research 2002 v.25 no.6 pp. 954-963
ISSN:
0253-6269
Subject:
immune response,   etc   ; agglutinins; antineoplastic agents; interleukin-12; interleukin-6; lectins; macrophages; messenger RNA; reverse transcriptase polymerase chain reaction; wheat germ;     Show all 10 Subjects
Abstract:
... Lectin-conjugated praecoxin A is a compound, which is combined Wheat Germ Agglutinin (WGA) Lectin with praecoxin A and also known to have an anti-tumor activity. In our lab, in order to investigate its immune reaction other than the anti-tumor activity ever known, we examined cytokines such as IL-6 and IL-12 through their mRNA expressions, which are generally secreted by macrophage bothin vivo and ...
DOI:
10.1007/BF02977019

28. Biotin Supplementation Increases Expression of Genes Encoding Interferon-γ, Interleukin-1β, and 3-Methylcrotonyl-CoA Carboxylase, and Decreases Expression of the Gene Encoding Interleukin-4 in Human Peripheral Blood Mononuclear Cells

Author:
Wiedmann, Silke; Eudy, James D.; Zempleni, Janos
Source:
Journal of nutrition 2003 v.133 no.3 pp. 716-719
ISSN:
0022-3166
Subject:
immune response,   etc   ; adults; antigens; apoptosis; biotin; cell proliferation; concanavalin A; cultured cells; gene expression; gene expression regulation; genes; homeostasis; humans; interferon-gamma; interleukin-4; messenger RNA; metabolism; microarray technology; mononuclear leukocytes; reverse transcriptase polymerase chain reaction; secretion; signal transduction; stress response;     Show all 23 Subjects
Abstract:
... Stimulation of immune cells by antigens triggers changes in the transcription of genes encoding cytokines and other proteins; these changes in gene expression are part of the normal immune response. Previous studies have provided evidence that biotin status may affect secretion of cytokines by immune cells. Here we determined whether biotin supplementation affects gene expression in human immune c ...

29. Regulation of Zinc Metabolism and Genomic Outcomes

Author:
Cousins, Robert J.; Blachard, Raymond K.; Moore, J. Bernadette; Cui, Li; Green, Calvert L.; Liuzzi, Juan P.; Cao, Jay; Bobo, Jeffrey A.
Source:
Journal of nutrition 2003 v.133 no.5 pp. 1521S-1526S
ISSN:
0022-3166
Subject:
immune response,   etc   ; DNA repair; cholecystokinin; complementary DNA; energy; genes; genomics; heat shock proteins; humans; kidneys; lactation; messenger RNA; metabolism; monocytes; pregnancy; signal transduction; small intestine; stress response; transcriptome; transporters; tyrosine; zinc;     Show all 22 Subjects
Abstract:
... Differential mRNA display and cDNA array analysis have identified zinc-regulated genes in small intestine, thymus and monocytes. The vast majority of the transcriptome is not influenced by dietary zinc intake, high or low. Of the genes that are zinc regulated, most are involved in signal transduction (particularly influencing the immune response), responses to stress and redox, growth and energy u ...

30. Simultaneous quantitation of equine cytokine mRNAs using a multi-probe ribonuclease protection assay

Author:
Lim, W.S.; Edwards, J.F.; Boyd, N.K.; Payne, S.L.; Ball, J.M.
Source:
Veterinary immunology and immunopathology 2003 v.91 no.1 pp. 45-51
ISSN:
0165-2427
Subject:
immune response,   etc   ; RNA probes; actin; antisense RNA; genes; horses; interferon-gamma; interleukin-10; interleukin-12; interleukin-1alpha; interleukin-1beta; interleukin-6; interleukin-8; macrophages; messenger RNA; mononuclear leukocytes; plasmids; radiolabeling; ribonucleases; tumor necrosis factor-alpha;     Show all 20 Subjects
Abstract:
... A rapid multi-probe ribonuclease protection assay (RPA) was developed to quantitate equine-specific cytokine mRNA levels in activated equine monocyte-derived macrophages (EMDM) and equine peripheral blood mononuclear cells (EPBMC). Eleven template plasmids specific to 10 equine cytokine genes and the β-actin gene were generated from which radiolabeled anti-sense RNA probes were produced. The multi ...
DOI:
10.1016/S0165-2427(02)00263-5

31. Hidden from the host; Spiroplasma bacteria infecting Drosophila do not cause an immune response, but are suppressed by ectopic immune activation

Author:
Hurst, G.D.D.; Anbutsu, H.; Kutsukake, M.; Fukatsu, T.
Source:
Insect molecular biology 2003 v.12 no.1 pp. 93-97
ISSN:
0962-1075
Subject:
immune response,   etc   ; septic shock; messenger RNA; immune evasion; host-pathogen relationships; mutation; insect immunity; antimicrobial peptides; gene expression; hemolymph; gene induction; Spiroplasma poulsonii; Drosophila melanogaster; bacterial infections;     Show all 14 Subjects
DOI:
10.1046/j.1365-2583.2003.00380.x
PubMed:
12542640

32. Expression of messenger ribonucleic acid and production of cytokines in children with malnutrition

Author:
Bhaskaram, P.; Hemalatha, R.; Goud, B. Narayana
Source:
Nutrition research 2003 v.23 no.3 pp. 367-376
ISSN:
0271-5317
Subject:
immune response,   etc   ; adults; antigens; children; diet therapy; enzyme-linked immunosorbent assay; gene expression; interferon-gamma; interleukin-10; interleukin-2; interleukin-4; interleukin-5; kwashiorkor; lymphocytes; messenger RNA; protein secretion; reverse transcriptase polymerase chain reaction; volunteers;     Show all 18 Subjects
Abstract:
... The aim of this study was to determine the IL2 and IL4 mRNA expression by antigen/mitogen stimulated lymphocytes and IL2, IFN-γ, IL4, IL5 and IL10 protein secretion from the culture supernatant obtained from children suffering from severe protein energy malnutrition (PEM) and compare with the responses of normal healthy children. Twelve children aged between 3 and 5 years hospitalised for rehabili ...

33. Temporal changes in cytokine expression of foals during the first month of life

Author:
Boyd, N.K.; Cohen, N.D.; Lim, W.S.; Martens, R.J.; Chaffin, M.K.; Ball, J.M.
Source:
Veterinary immunology and immunopathology 2003 v.92 no.1-2 pp. 75-85
ISSN:
0165-2427
Subject:
immune response,   etc   ; disease severity; farms; foals; infectious diseases; interferon-gamma; interleukin-10; interleukin-1alpha; interleukin-1beta; interleukin-2; interleukin-4; interleukin-6; interleukin-8; messenger RNA; models; mononuclear leukocytes; ribonucleases; temporal variation; transforming growth factor beta 1; tumor necrosis factor-alpha;     Show all 20 Subjects
Abstract:
... Foals are uniquely susceptible to a wide variety of opportunistic infections normally associated with immunodeficiencies. Little is understood about the immune system of foals during the neonatal period. An apparent age-related susceptibility predisposes neonatal foals to infectious diseases and hinders therapeutic and preventative interventions for these diseases. Cytokine expression is correlate ...
DOI:
10.1016/S0165-2427(03)00021-7

34. Dynamics of Rickettsia-tick interactions: identification and characterization of differentially expressed mRNAs in unifected and infected Dermacentor variabilis

Author:
Mulenga, A.; Macaluso, K.R.; Simser, J.A.; Azad, A.F.
Source:
Insect molecular biology 2003 v.12 no.2 pp. 185-193
ISSN:
0962-1075
Subject:
immune response,   etc   ; messenger RNA; ticks; disease vectors; complementary DNA; Dermacentor variabilis; hemocytes; Rickettsia montanensis; transovarial transmission; nucleotide sequences; gene expression regulation; sequence homology; infection;     Show all 13 Subjects
DOI:
10.1046/j.1365-2583.2003.00400.x

35. Expression of immune genes in turbot (Scophthalmus maximus) fed a nucleotide-supplemented diet

Author:
Low, C.; Wadsworth, S.; Burrells, C.; Secombes, C.J.
Source:
Aquaculture 2003 v.221 no.1-4 pp. 23-40
ISSN:
0044-8486
Subject:
immune response,   etc   ; lysozyme; messenger RNA; immunoglobulin M; transferrin; interleukin-1; gills; nucleotides; gene expression regulation; transforming growth factor beta; Scophthalmus maximus; immunoglobulin genes; spleen; feed supplements; fish feeding; kidneys;     Show all 16 Subjects
Abstract:
... Turbot (Scophthalmus maximus) fed a control or nucleotide-supplemented diet for 15 weeks were examined for the relative expression of a number of immune genes. Genes analysed included those involved in specific immune responses, such as immunoglobulin M (IgM) and recombinase activating gene 1 (RAG-1), and a number of genes important for nonspecific defences (transferrin, lysozyme, cytokines). Afte ...

36. Use of a Sindbis virus DNA-based expression vector for induction of protective immunity against pseudorabies virus in pigs

Author:
Dufour, Vinciane; Boisseson, Claire De
Source:
Veterinary immunology and immunopathology 2003 v.93 no.3-4 pp. 125-134
ISSN:
0165-2427
Subject:
immune response,   etc   ; Suid alphaherpesvirus 1; Sindbis virus; messenger RNA; protein synthesis; antigens; interferon-gamma; muscles; cell-mediated immunity; live vaccines; plasmids; neutralizing antibodies; recombinant vaccines; mononuclear leukocytes; virulence; glycoproteins; swine;     Show all 17 Subjects
Abstract:
... Injection of plasmid DNA encoding pseudorabies virus (PRV) glycoproteins into pig muscle has been shown to result in protective immunity against lethal infection. Nevertheless, such DNA vaccines are still less efficient than some attenuated or killed live vaccines. One way to increase DNA vaccine efficacy is to improve the vectorisation system at the molecular level, thereby enhancing the rate of ...
DOI:
10.1016/S0165-2427(03)00066-7

37. Analysis of constitutive cytokine expression by pigs infected in-utero with porcine reproductive and respiratory syndrome virus

Author:
Feng, W.H.; Tompkins, M.B.; Xu, J.S.; Zhang, H.X.; McCaw, M.B.
Source:
Veterinary immunology and immunopathology 2003 v.94 no.1-2 pp. 35-45
ISSN:
0165-2427
Subject:
immune response,   etc   ; Porcine reproductive and respiratory syndrome virus; T-lymphocytes; cell-mediated immunity; delayed hypersensitivity; gene expression; immunomodulation; interferon-gamma; interleukin-10; interleukin-12; interleukin-2; interleukin-4; interleukin-6; messenger RNA; pathogens; piglets; tuberculin;     Show all 17 Subjects
Abstract:
... To investigate cytokine alterations in pigs infected in-utero with porcine reproductive and respiratory syndrome virus (PRRSV), constitutive mRNA expression by peripheral blood mononuclear cells (PBMCs) was measured. PBMC from in-utero PRRSV-infected pigs displayed significantly increased IL-6, IL-10, and IFN-γ mRNA expression at 0 and 14 days of age compared with age-matched control pigs. There w ...
DOI:
10.1016/S0165-2427(03)00059-X

38. Restraint stress and anti-tumor immune response in mice

Author:
Posevitz, V.; Vizler, C.; Benyhe, S.; Duda, E.; Borsodi, Anna
Source:
Acta biologica Hungarica 2003 v.54 no.2 pp. 167-176
ISSN:
0236-5383
Subject:
immune response,   etc   ; apoptosis; immunomodulation; interferon-gamma; interleukin-1alpha; interleukin-1beta; interleukin-2; interleukin-3; interleukin-4; interleukin-5; interleukin-6; lung neoplasms; lymphotoxin; melanoma; messenger RNA; metastasis; mice; psychological stress; spleen; thymus gland; tumor necrosis factor-alpha;     Show all 21 Subjects
Abstract:
... Psychological stress modulates the immune system through the hypothalamic-pituitary-adrenal axis, the sympatho-adrenomedullary axis and the opioid system. According to literature data, restraint stress increases the immune cell apoptosis, decreases the spleen and thymus cell content, the natural killer (NK) activity in the spleen, and it compromises the anti-tumor immune response in mice. We immob ...
DOI:
10.1556/ABiol.54.2003.2.5

39. Haemocytes from Pseudoplusia includens express multiple α and β integrin subunits

Author:
Lavine, M.D.; Strand, M.R.
Source:
Insect molecular biology 2003 v.12 no.5 pp. 441-452
ISSN:
0962-1075
Subject:
immune response,   etc   ; Pseudoplusia includens; hemocytes; membrane proteins; receptors; protein subunits; nucleotide sequences; amino acid sequences; sequence homology; phylogeny; transcription (genetics); gene expression regulation; messenger RNA; insect immunity; cell adhesion;     Show all 15 Subjects
Abstract:
... Cellular immune responses such as encapsulation involve the adhesion of one or more classes of haemocytes. How insect haemocytes recognize encapsulation targets as foreign or the identity of the molecules regulating haemocyte adhesion is unknown. One of the most important classes of adhesion receptors in mammalian immune cells is the integrins, which form functional heterodimers through different ...
DOI:
10.1046/j.1365-2583.2003.00428.x

40. Transforming growth factor-β response to mycobacterial infection in striped bass Morone saxatilis and hybrid tilapia Oreochromis spp

Author:
Harms, Craig A.; Howard, Kristina E.; Wolf, Jeffrey C.; Smith, Stephen A.; Kennedy-Stoskopf, Suzanne
Source:
Veterinary immunology and immunopathology 2003 v.95 no.3-4 pp. 155-163
ISSN:
0165-2427
Subject:
immune response,   etc   ; Morone saxatilis; Mycobacterium marinum; Oreochromis; fish; gene expression; granuloma; hybrids; image analysis; inflammation; kidneys; liver; messenger RNA; mycobacterial diseases; polymerase chain reaction; reverse transcription; transforming growth factor beta;     Show all 17 Subjects
Abstract:
... Striped bass (Morone saxatilis) and hybrid tilapia (Oreochromis spp.) were experimentally infected with Mycobacterium marinum. Splenic mononuclear cell transforming growth factor-β (TGF-β) mRNA was measured by reverse transcription quantitative-competitive PCR (RT-qcPCR). In histologic sections of liver and anterior kidney, the area of each section that was occupied by granulomas and the total are ...
DOI:
10.1016/S0165-2427(03)00138-7

41. Expression of interleukin 4, interleukin 4 splice variants and interferon gamma mRNA in calves experimentally infected with Fasciola hepatica

Author:
Waldvogel, A.S.; Lepage, M.F.; Zakher, A.; Reichel, M.P.; Eicher, R.; Heussler, V.T.
Source:
Veterinary immunology and immunopathology 2004 v.97 no.1-2 pp. 53-63
ISSN:
0165-2427
Subject:
immune response,   etc   ; CD4-positive T-lymphocytes; Fasciola hepatica; calves; gene expression; helminthiasis; humans; interferon-gamma; interleukin-4; lymph nodes; messenger RNA; quantitative analysis;     Show all 12 Subjects
Abstract:
... Interleukin 4 (IL-4) is expected to play a dominant role in the development of T helper (Th) 2 cells. Th2 immune responses with expression of relatively large amounts of interleukin 4 (IL-4) but little interferon γ (IFN-γ) are characteristic for chronic helminth infections. But no information is available about IL4 expression during early Fasciola hepatica (F. hepatica) infections in cattle. There ...
DOI:
10.1016/j.vetimm.2003.08.002

42. Immune stimulation in the silkworm, Bombyx mori L., by CpG oligodeoxynucleotides

Author:
Kim, I.; Kim, S.H.; Lee, Y.S.; Yun, E.K.; Lee, H.S.; Kim, J.W.; Ryu, K.S.; Kang, P.D.; Lee, I.H.
Source:
Archives of insect biochemistry and physiology 2004 v.55 no.1 pp. 43-48
ISSN:
0739-4462
Subject:
immune response,   etc   ; Bombyx mori; silkworms; instars; larvae; insect immunity; oligonucleotides; cytosine; guanine; nucleotide sequences; methylation; injection; antibacterial proteins; antimicrobial peptides; gene induction; gene expression; messenger RNA;     Show all 17 Subjects
Abstract:
... Synthetic ODNs containing unmethylated CpG dinucleotides are known to stimulate immune responses in vertebrates, but so far the effect has not been studied in insects. In this report, we describe an induction of immune response following injection of oligodeoxynucleotides (ODNs) into the insect hemocoel. The fifth instar silkworm (Bombyx mori L.) larvae were injected with several synthetic ODNs co ...
DOI:
10.1002/arch.10122
PubMed:
14691962

43. An immune responsive factor D-like serine proteinase homologue identified from the American dog tick, Dermacentor variabilis

Author:
Simser, J.A.; Mulenga, A.; Macaluso, K.R.; Azad, A.F.
Source:
Insect molecular biology 2004 v.13 no.1 pp. 25-35
ISSN:
0962-1075
Subject:
immune response,   etc   ; Dermacentor variabilis; ticks; hemocytes; serine proteinases; complementary DNA; nucleotide sequences; amino acid sequences; sequence homology; gene expression; messenger RNA; tissue distribution; Escherichia coli;     Show all 13 Subjects
Abstract:
... A Dermacentor variabilis cDNA encoding a clip-domain serine proteinase homologue with glycine replacing the catalytic serine was identified from tick haemocytes. The D. variabilis product was most similar to Tachypleus tridentatus haemocyte antimicrobial factor D and shared significant homologies with a number of immune-responsive gene products of arthropods, including insect prophenoloxidase-acti ...
DOI:
10.1111/j.1365-2583.2004.00455.x
PubMed:
14728664

44. Bacterial challenge stimulates innate immune responses in extra-embryonic tissues of tobacco hornworm eggs

Author:
Gorman, M.J.; Kankanala, P.; Kanost, M.R.
Source:
Insect molecular biology 2004 v.13 no.1 pp. 19-24
ISSN:
0962-1075
Subject:
immune response,   etc   ; lysozyme; messenger RNA; melanization; ova; Manduca sexta; insect immunity; embryo (animal); gene expression; antimicrobial proteins; gene induction; immunocompetence; bacterial infections;     Show all 13 Subjects
Abstract:
... Innate immunity protects juvenile and adult vertebrates and invertebrates against potential pathogens; however, it is unknown when developing embryos become immune competent and just how they are guarded from infection. To address these questions, we studied the effect of immune challenge on early stage eggs of the tobacco hornworm, Manduca sexta. We detected many immune-related proteins and mRNAs ...
DOI:
10.1111/j.1365-2583.2004.00454.x
PubMed:
14728663

45. Failure of FIV-infected cats to control Toxoplasma gondii correlates with reduced IL2, IL6, and IL12 and elevated IL10 expression by lymph node T cells

Author:
Levy, Julie K.; Liang, Yinghua; Ritchey, Jerry W.; Davidson, Michael G.; Tompkins, Wayne A.; Tompkins, Mary B.
Source:
Veterinary immunology and immunopathology 2004 v.98 no.1-2 pp. 101-111
ISSN:
0165-2427
Subject:
immune response,   etc   ; HIV infections; T-lymphocytes; Toxoplasma gondii; cats; gene expression; interleukin-10; interleukin-12; interleukin-2; interleukin-6; lymph nodes; messenger RNA; pathogens;     Show all 13 Subjects
Abstract:
... Increased susceptibility to intracellular pathogens in HIV-infected individuals and FIV-infected cats is attributed to a defective T-helper 1 (Th1) immune response. However, little is known about specific cytokine responses to secondary pathogens. To address this question, control and FIV-infected cats were challenged with Toxoplasma gondii, and lymph node cells analyzed for cytokine mRNA expressi ...
DOI:
10.1016/j.vetimm.2003.11.002

46. Recombinant single-chain canine interleukin 12 induces interferon gamma mRNA expression in peripheral blood mononuclear cells of dogs with visceral leishmaniasis

Author:
Santos, Lenita Ramires dos; Barrouin-Melo, Stella Maria; Chang, Yung-Fu; Olsen, John; McDonough, Sean P.; Quimby, Fred; Santos, Washington Luis Conrado dos; Pontes-de-Carvalho, Lain Carlos; Sá Oliveira, Geraldo Gileno de
Source:
Veterinary immunology and immunopathology 2004 v.98 no.1-2 pp. 43-48
ISSN:
0165-2427
Subject:
immune response,   etc   ; antigens; dogs; gene expression; interferon-gamma; interleukin-12; messenger RNA; mononuclear leukocytes; public health; veterinary medicine; visceral leishmaniasis;     Show all 11 Subjects
Abstract:
... Canine visceral leishmaniasis poses important concerns for public health and veterinary medicine in many areas of the world. Resistance to it seems to be associated with cellular specific immune responses of the so-called Th1 type. Interleukin-12 (IL-12) is one of the most potent inducers of Th1 type of immune responses to co-administered antigens. Herein, the cloning of canine IL-12, as a single- ...
DOI:
10.1016/j.vetimm.2003.10.006

47. Use of recombinant modified vaccinia Ankara viral vectors for equine influenza vaccination

Author:
Breathnach, C.C.; Rudersdorf, R.; Lunn, D.P.
Source:
Veterinary immunology and immunopathology 2004 v.98 no.3-4 pp. 127-136
ISSN:
0165-2427
Subject:
immune response,   etc   ; Influenza A virus; antibodies; antigens; blood serum; equine influenza; genes; hemagglutinins; homologous recombination; horses; interferon-gamma; loci; messenger RNA; neck; nucleoproteins; pathogens; plasmids; vaccination; viruses;     Show all 19 Subjects
Abstract:
... Recombinant modified vaccinia Ankara (MVA) vectors expressing equine influenza virus genes were constructed and evaluated for use in equine vaccination. Two strains of recombinant MVA, expressing either hemagglutinin (HA) or nucleoprotein (NP) genes were constructed. Each influenza virus gene was cloned from A/equine/Kentucky/1/81 (Eq/Ky) into an MVA construction plasmid, and was introduced to the ...
DOI:
10.1016/j.vetimm.2003.11.004

48. Equine β-defensin-1: full-length cDNA sequence and tissue expression

Author:
Davis, Elizabeth G.; Sang, Yongming; Blecha, Frank
Source:
Veterinary immunology and immunopathology 2004 v.99 no.1-2 pp. 127-132
ISSN:
0165-2427
Subject:
immune response,   etc   ; messenger RNA; complementary DNA; innate immunity; horses; expressed sequence tags; cysteine; reverse transcriptase polymerase chain reaction; antimicrobial peptides; databases; swine;     Show all 11 Subjects
Abstract:
... β-Defensins are cysteine-rich endogenously produced antimicrobial peptides that play an important role in innate immune defense. Although, previous investigations have identified β-defensins in several mammalian species, no reports have identified equine β-defensins. Using a strategy of database searching for expressed sequence tags (EST) we identified putative expression of equine β-defensins in ...
DOI:
10.1016/j.vetimm.2003.12.010

49. Upregulation of transforming growth factor-beta and interleukin-10 in cows with clinical Johne’s disease

Author:
Khalifeh, M.S.; Stabel, J.R.
Source:
Veterinary immunology and immunopathology 2004 v.99 no.1-2 pp. 39-46
ISSN:
0165-2427
Subject:
immune response,   etc   ; Mycobacterium avium subsp. paratuberculosis; cows; diarrhea; disease course; gene expression; genes; ileum; interferon-gamma; interleukin-10; lymph nodes; messenger RNA; reverse transcriptase polymerase chain reaction; tissues; transforming growth factor beta; weight loss;     Show all 16 Subjects
Abstract:
... Johne’s disease progresses through distinct stages including a protracted subclinical stage in which the infection appears to be controlled; followed by a more acute stage in which the host animal demonstrates clinical signs such as diarrhea and weight loss. Little is known about the dynamics of the host immune response during these two phases of disease, however, it is possible that immune modula ...
DOI:
10.1016/j.vetimm.2004.01.009

50. A novel lectin with a fibrinogen-like domain and its potential involvement in the innate immune response of Armigeres subalbatus against bacteria

Author:
Wang, X.; Rocheleau, T.A.; Fuchs, J.F.; Hillyer, J.F.; Chen, C.C.; Christensen, B.M.
Source:
Insect molecular biology 2004 v.13 no.3 pp. 273-282
ISSN:
0962-1075
Subject:
immune response,   etc   ; sequence alignment; phylogeny; receptors; Micrococcus luteus; structural genes; binding properties; insect immunity; Armigeres subalbatus; gene expression regulation; Escherichia coli; messenger RNA; complementary DNA; amino acid sequences; fibrinogen; lectins; nucleotide sequences; sequence homology; hemocytes;     Show all 19 Subjects
Abstract:
... Mosquitoes have an efficient cellular innate immune response that includes phagocytosis of microbial pathogens and encapsulation of metozoan parasites. In this study, we describe a novel lectin in the mosquito, Armigeres subalbatus (aslectin or AL-1). The 1.27 kb cDNA clone for the AL-1 gene (AL-1) encodes a 279 deduced amino acid sequence that contains a C-terminal fibrinogen-like domain. AL-1 is ...
DOI:
10.1111/j.0962-1075.2004.00484.x
PubMed:
15157228

51. Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/Chlamydophila

Author:
Entrican, Gary; Wattegedera, Sean; Rocchi, Mara; Fleming, Diana C.; Kelly, Rodney W.; Wathne, Gwen; Magdalenic, Vjera; Howie, Sarah E.M.
Source:
Veterinary immunology and immunopathology 2004 v.100 no.3-4 pp. 179-186
ISSN:
0165-2427
Subject:
immune response,   etc   ; Chlamydia; Chlamydophila; Gram-negative bacteria; chronic diseases; complications (disease); epithelial cells; gene expression; hosts; humans; inflammation; interleukin-8; lipopolysaccharides; messenger RNA; transcription factor NF-kappa B;     Show all 15 Subjects
Abstract:
... Chlamydia/Chlamydophila are a family of intracellular gram-negative bacteria that infect their hosts primarily via mucosal epithelia. Chronic disease associated with bacterial persistence, inflammation and tissue damage are common sequelae of infection with these organisms. Human epithelial cell lines respond to infection by releasing pro-inflammatory cytokines and chemokines such as interleukin ( ...
DOI:
10.1016/j.vetimm.2004.04.006

52. Quantitative analysis of interleukin-6 expression in porcine spleen cells and alveolar macrophages using real-time PCR

Author:
Lee, D.Y.; Cho, Y.W.; Kang, S.G.; Shin, N.R.; Choi, I.S.; Shin, S.J.; Yoo, H.S.
Source:
Veterinary research communications 2004 v.28 no.6 pp. 503-513
ISSN:
0165-7380
Subject:
immune response,   etc   ; temporal variation; messenger RNA; lipopolysaccharides; pulmonary alveoli; hematopoiesis; swine diseases; macrophages; interleukin-6; polymerase chain reaction; amino acid sequences; gene expression; spleen; nucleotide sequences; sequence homology; bacterial infections; swine;     Show all 17 Subjects
DOI:
10.1023/B:VERC.0000040242.85968.e0
PubMed:
15509024

53. cDNA cloning and mRNA expression of the lipopolysaccharide- and beta-1,3-glucan-binding protein gene from scallop Chlamys farreri

Author:
Su, J.; Song, L.; Xu, W.; Wu, L.; Li, H.; Xiang, J.
Source:
Aquaculture 2004 v.239 no.1-4 pp. 69-80
ISSN:
0044-8486
Subject:
immune response,   etc   ; Chlamys; scallops; lectins; complementary DNA; sequence analysis; messenger RNA; gene expression regulation; polypeptides; molecular weight; isoelectric point; Vibrio anguillarum; nucleotide sequences; amino acid sequences; China;     Show all 15 Subjects
Abstract:
... Lipopolysaccharide and beta-1,3-glucan-binding protein (LGBP) play a crucial role in the innate immune response of invertebrates as a pattern recognition protein (PRP). The scallop LGBP gene was obtained from Chlamys farreri challenged by Vibrio anguillarum by randomly sequencing cDNA clones from a whole body cDNA library, and by fully sequencing a clone with homology to known LGBP genes. The scal ...

54. Mucosal FOXP3-Expressing CD4⁺ CD25[superscript high] Regulatory T Cells in Helicobacter pylori-Infected Patients

Author:
Lundgren, Anna; Strömberg, Erika; Sjöling, Åsa; Lindholm, Catharina; Enarsson, Karin; Edebo, Anders; Johnsson, Erik; Suri-Payer, Elisabeth; Larsson, Pia; Rudin, Anna; Svennerholm, Ann-Mari; Lundin, B. Samuel
Source:
Infection and immunity 2005 v.73 no.1 pp. 523-531
ISSN:
0019-9567
Subject:
immune response,   etc   ; Helicobacter pylori; T-lymphocytes; adenocarcinoma; antigens; cytotoxicity; duodenum; genes; messenger RNA; mucosa; patients; peptic ulcers; phenotype; stomach;     Show all 14 Subjects
Abstract:
... Helicobacter pylori chronically colonizes the stomach and duodenum and causes peptic ulcers or gastric adenocarcinoma in 10 to 20% of infected individuals. We hypothesize that the inability of patients to clear H. pylori infections is a consequence of active suppression of the immune response. Here we show that H. pylori-infected individuals have increased frequencies of CD4⁺ CD25[superscript high ...
DOI:
10.1128/IAI.73.1.523-531.2005

55. Effects of microcystin-LR on patterns of iNOS and cytokine mRNA expression in macrophages in vitro

Author:
Chen, T.; Shen, P.; Zhang, J.; Hua, Z.
Source:
Environmental toxicology 2005 v.20 no.1 pp. 85-91
ISSN:
1520-4081
Subject:
immune response,   etc   ; water pollution; microcystin-LR; mice; laboratory animals; macrophages; cytokines; nitric oxide synthase; messenger RNA; gene expression; reverse transcriptase polymerase chain reaction; in vitro studies;     Show all 12 Subjects
Abstract:
... The presence of cyanobacterial toxins in drinking and recreational waters represent a potential health hazard to the public. Microcystin-LR (MC-LR) is the most commonly encountered toxin and is a potent cyclic heptapeptide hepatotoxin produced by cyanobacteria. In this study, the immunomodulation by MC-LR of BALB/c mice peritoneal macrophages was investigated in vitro on mRNA levels of induced nit ...
DOI:
10.1002/tox.20081
PubMed:
15712326

56. Different expression of Litopenaeus vannamei (Boone) haemocytes to Vibrio and abiotic particle inoculation

Author:
Montano-Perez, K.; Gomez-Gamez, A.I.; Vargas-Albores, F.
Source:
Aquaculture research 2005 v.36 no.9 pp. 912-919
ISSN:
1355-557X
Subject:
immune response,   etc   ; Litopenaeus vannamei; shrimp; hemocytes; Vibrio alginolyticus; animal pathogenic bacteria; gene expression regulation; complementary DNA; messenger RNA; amino acid sequences; nucleotide sequences; shrimp culture;     Show all 12 Subjects
Abstract:
... Penaeid shrimps are among the most studied crustaceans, mainly regarding their immune system, and several proteins involved in the defense against pathogens have been described. Haemocytes are very dynamic cells responsible of recognition, phagocytosis, degranulation and nodule formation, but still little is known about their gene expression. Using differential display, we found modification in ha ...
DOI:
10.1111/j.1365-2109.2005.01301.x

57. Short-term effects on pro-inflammatory cytokine, lactoferrin and CD14 mRNA expression levels in bovine immunoseparated milk and blood cells treated by LPS

Author:
Prgomet, C.; Sarikaya, H.; Bruckmaier, R.M.; Pfaffl, M.W.
Source:
Journal of veterinary medicine 2005 v.52 no.7 pp. 317-324
ISSN:
0931-184X
Subject:
immune response,   etc   ; lipopolysaccharides; Erynia neoaphidis; entomopathogenic fungi; inoculum density; membrane glycoproteins; somatic cell count; estimation; conidia; biological control agents; macrophages; immunomagnetic separation; cytokines; Acyrthosiphon pisum; Myzus persicae; blood cells; mammary glands; gene expression regulation; Escherichia coli; messenger RNA; insect pests; cattle; transcription (genetics); bioassays; lactoferrin; spatial variation; adverse effects; Metopolophium dirhodum; inflammation; reverse transcriptase polymerase chain reaction; cultured cells; bovine mastitis;     Show all 32 Subjects
DOI:
10.1111/j.1439-0442.2005.00741.x
PubMed:
16109097

58. Cytokine responses in broiler lines that differ in susceptibility to malabsorption syndrome

Author:
Rebel, J.M.J.; Balk, F.R.M.; Boersma, W.J.A.
Source:
British poultry science 2005 v.46 no.6 pp. 679-686
ISSN:
0007-1668
Subject:
immune response,   etc   ; broiler chickens; breed differences; messenger RNA; chicken breeds; poultry diseases; interleukin-2; transcription (genetics); interleukin-6; disease resistance; malabsorption; small intestine; breeding lines; interferons; interleukin-8;     Show all 15 Subjects
Abstract:
... 1. Based on earlier studies it was hypothesised that there is an immunological basis for the differences in susceptibility to malabsorption syndrome (MAS). A study was conducted to investigate base-line and MAS-induced cytokine levels in the intestine of broilers that differ in MAS susceptibility. 2. The transcription of cytokine mRNA in the intestine was quantified using a real-time polymerase ch ...
DOI:
10.1080/00071660500395541
PubMed:
16428110

59. Staying alive in adversity: transcriptome dynamics in the stress-resistant dauer larva

Author:
Holt, Suzan J.
Source:
Functional & integrative genomics 2006 v.6 no.4 pp. 285-299
ISSN:
1438-793X
Subject:
immune response,   etc   ; Caenorhabditis elegans; gene expression; messenger RNA; nematode larvae; protein synthesis; ribosomes; soil nematodes; stress response; transcriptome; translation (genetics);     Show all 11 Subjects
Abstract:
... In response to food depletion and overcrowding, the soil nematode Caenorhabditis elegans can arrest development and form an alternate third larval stage called the dauer. Though nonfeeding, the dauer larva is long lived and stress resistant. Metabolic and transcription rates are lowered but the transcriptome of the dauer is complex. In this study, distribution analysis of transcript profiles gener ...
DOI:
10.1007/s10142-006-0024-5
PubMed:
16636823

60. Construction of a normalized Bos taurus and Bos indicus macrophage-specific cDNA library

Author:
Jensen, K.; Speed, D.; Paxton, E.; Williams, J.L.; Glass, E.J.
Source:
Animal genetics 2006 v.37 no.1 pp. 75-77
ISSN:
0268-9146
Subject:
immune response,   etc   ; cattle; zebu; macrophages; complementary DNA; genomic libraries; transcription (genetics); Theileria annulata; protozoal infections; cattle diseases; messenger RNA; lipopolysaccharides; Escherichia coli; nucleotide sequences;     Show all 14 Subjects
DOI:
10.1111/j.1365-2052.2005.01407.x
PubMed:
16441303

61. Real-time RT-PCR quantification of mRNA encoding cytokines, CC chemokines and CCR3 in bronchial biopsies from dogs with eosinophilic bronchopneumopathy

Author:
Peeters, D.; Peters, I.R.; Clercx, C.; Day, M.J.
Source:
Veterinary immunology and immunopathology 2006 v.110 no.1-2 pp. 65-77
ISSN:
0165-2427
Subject:
immune response,   etc   ; animal proteins; respiratory tract diseases; receptors; cytokines; gene expression; mucosa; CD4-positive T-lymphocytes; pathogenesis; bronchi; CD8-positive T-lymphocytes; messenger RNA; dogs; pets; glyceraldehyde-3-phosphate dehydrogenase; eosinophilia; dog diseases; reverse transcriptase polymerase chain reaction; quantitative genetics;     Show all 19 Subjects
Abstract:
... Idiopathic canine eosinophilic bronchopneumopathy (EBP) is a disease characterized by eosinophilic infiltration of the pulmonary interstitium and bronchial mucosa, a cause for which has not yet been discovered. A recent study, examining the relative proportion of various lymphocyte cell subsets within bronchoalveolar lavage fluid from dogs with EBP, has shown a selective increase in CD4+ T-cells a ...
DOI:
10.1016/j.vetimm.2005.09.004

62. Heterophil cytokine mRNA profiles from genetically distinct lines of chickens with differential heterophil-mediated innate immune responses

Author:
Swaggerty, C.L.; Kaiser, P.; Rothwell, L.; Pevzner, I.Y.; Kogut, M.H.
Source:
Avian pathology 2006 v.35 no.2 pp. 102-108
ISSN:
0307-9457
Subject:
immune response,   etc   ; chickens; messenger RNA; carrier state; immunocompetence; Salmonella Enteritidis; cytokines; animal pathogenic bacteria; reverse transcriptase polymerase chain reaction; food pathogens; disease resistance; phagocytes; line differences; heterophils;     Show all 14 Subjects
Abstract:
... Previously we demonstrated that increased in-vitro heterophil function translates to increased in-vivo resistance to Salmonella enteritidis infections in broilers (line A > B). Heterophils produce cytokines and modulate acute protection against Salmonella in neonatal poultry. We hypothesized that heterophils from S. enteritidis-resistant chickens produce an up-regulated pro-inflammatory cytokine/c ...
DOI:
10.1080/03079450600597535
PubMed:
16595301

63. Immulectin-4 from the tobacco hornworm Manduca sexta binds to lipopolysaccharide and lipoteichoic acid

Author:
Yu, X.-Q.; Ling, E.; Tracy, M.E.; Zhu, Y.
Source:
Insect molecular biology 2006 v.15 no.2 pp. 119-128
ISSN:
0962-1075
Subject:
immune response,   etc   ; Manduca sexta; lectins; complementary DNA; amino acid sequences; gene induction; fat body; messenger RNA; bacteria; recombinant proteins; binding properties; lipopolysaccharides; insect immunity;     Show all 13 Subjects
Abstract:
... Insect C-type lectins function as pattern recognition receptors in innate immunity. In the tobacco hornworm Manduca sexta, we have previously isolated three C-type lectins named immulectins, which are involved in innate immune responses. Here, we report a new member of the immulectin family, immulectin-4 (IML-4). IML-4 mRNA was detected in the fat body of control larvae and was induced in the fat ...
DOI:
10.1111/j.1365-2583.2006.00618.x
PubMed:
16640722

64. Immunopathological effects of porcine circovirus type 2 (PCV2) on swine alveolar macrophages by in vitro inoculation

Author:
Chang, H.W.; Jeng, C.R.; Lin, T.L.; Liu, J.J.; Chiou, M.T.; Tsai, Y.C.; Chia, M.Y.; Jan, T.R.; Pang, V.F.
Source:
Veterinary immunology and immunopathology 2006 v.110 no.3-4 pp. 207-219
ISSN:
0165-2427
Subject:
immune response,   etc   ; animal proteins; reactive oxygen species; pulmonary alveoli; macrophages; gene expression; gene expression regulation; mixed infection; apoptosis; interleukin-8; vertebrate viruses; messenger RNA; tumor necrosis factor-alpha; in vitro studies; Porcine circovirus; postweaning multisystemic wasting syndrome; swine; monocytes; neutrophils; chemotaxis;     Show all 20 Subjects
Abstract:
... Porcine circovirus type 2 (PCV2) is the primary causative agent of postweaning multisystemic wasting syndrome (PMWS), a multifactorial disease, in pigs. Monocyte/macrophage lineage cells, including alveolar macrophages (AMs), are the major target cells for PCV2. Swine AMs are essential for the pulmonary defense system against various pathogens. Concurrent infection of lung with opportunistic patho ...
DOI:
10.1016/j.vetimm.2005.09.016

65. Selective enhancement of the type 1 cytokine response by expression of a canine interleukin (IL)-12 fused heterodimeric DNA

Author:
Saldarriaga, O.A.; Perez, L.E.; Travi, B.L.; Melby, P.C.
Source:
Veterinary immunology and immunopathology 2006 v.110 no.3-4 pp. 377-388
ISSN:
0165-2427
Subject:
immune response,   etc   ; dogs; pets; interleukin-12; protein synthesis; gene expression; complementary DNA; recombinant DNA; cell-mediated immunity; vaccines; vaccination; messenger RNA; promoter regions; vaccine adjuvants;     Show all 14 Subjects
Abstract:
... Interleukin-12 (IL-12) is a heterodimeric cytokine that is a principal mediator of the innate immune response and modulator of acquired cell-mediated immunity. Administration of exogenous IL-12 can direct the host adaptive T cell response toward a type 1 phenotype. The co-administration of IL-12 with vaccine antigens has been shown to augment the vaccine-induced TH1 response and protection against ...
DOI:
10.1016/j.vetimm.2005.11.003

66. A transgenic silkworm expressing the immune-inducible cecropin B-GFP reporter gene

Author:
Imamura, M.; Nakahara, Y.; Kanda, T.; Tamura, T.; Taniai, K.
Source:
Insect biochemistry and molecular biology 2006 v.36 no.5 pp. 429-434
ISSN:
0965-1748
Subject:
immune response,   etc   ; Bombyx mori; transgenic insects; insect immunity; antimicrobial peptides; green fluorescent protein; reporter genes; Escherichia coli; gene induction; promoter regions; gene expression; messenger RNA; fat body; hemocytes;     Show all 14 Subjects
Abstract:
... To analyze cecropin B promoter (P-CecB) activity in vivo, we constructed transgenic silkworms that expressed EGFP under the control of P-CecB using the piggyBac transposable element. Genomic Southern blot analysis of the G1 and G2 generations indicated the stable insertion of EGFP in the genome. Injection of Escherichia coli cells into the larvae strongly induced EGFP expression in the fat bodies ...
DOI:
10.1016/j.ibmb.2006.03.002
PubMed:
16651190

67. Immune responses to commercial equine vaccines against equine herpesvirus-1, equine influenza virus, eastern equine encephalomyelitis, and tetanus

Author:
Holmes, M.A.; Townsend, H.G.G.; Kohler, A.K.; Hussey, S.; Beathnach, C.; Barnett, C.; Holland, R.; Lunn, D.P.
Source:
Veterinary immunology and immunopathology 2006 v.111 no.1-2 pp. 67-80
ISSN:
0165-2427
Subject:
immune response,   etc   ; vertebrate viruses; Equid alphaherpesvirus 1; bacterial infections; messenger RNA; Eastern equine encephalitis virus; viral diseases of animals and humans; Orthomyxoviridae; animal pathogenic bacteria; Clostridium tetani; gene expression; seroconversion; vaccination; horse diseases; horses; interferons;     Show all 16 Subjects
Abstract:
... Horses are commonly vaccinated to protect against pathogens which are responsible for diseases which are endemic within the general horse population, such as equine influenza virus (EIV) and equine herpesvirus-1 (EHV-1), and against a variety of diseases which are less common but which lead to greater morbidity and mortality, such as eastern equine encephalomyelitis virus (EEE) and tetanus. This s ...
DOI:
10.1016/j.vetimm.2006.01.010

68. Quantification of mRNA encoding cytokines and chemokines in nasal biopsies from dogs with sino-nasal aspergillosis

Author:
Peeters, D.; Peters, I.R.; Clercx, C.; Day, M.J.
Source:
Veterinary microbiology 2006 v.114 no.3-4 pp. 318-326
ISSN:
0378-1135
Subject:
immune response,   etc   ; dogs; dog diseases; sinusitis; aspergillosis; Aspergillus fumigatus; pathogenesis; gene expression regulation; biochemical pathways; inflammation; transforming growth factors; phagocytes; nasal mucosa; interleukins; in vitro studies; reverse transcriptase polymerase chain reaction; messenger RNA; immunomodulators; chemokines;     Show all 19 Subjects
Abstract:
... Canine sino-nasal aspergillosis is usually caused by Aspergillus fumigatus and is similar to human chronic erosive non-invasive fungal sinusitis. The pathogenesis of the disease is poorly understood. We investigated the nature of the local immune response mounted in canine sino-nasal aspergillosis. Quantitative RT-PCR was carried out on RNA isolated from nasal biopsies from diseased and control do ...
DOI:
10.1016/j.vetmic.2005.11.065

69. Differential Expression of Immune Response Genes in Steller Sea Lions (Eumetopias jubatus): An Indicator of Ecosystem Health?

Author:
Bowen, Lizabeth; Aldridge, Brian; Beckmen, Kimberlee; Gelatt, Tom; Rea, Lorrie; Burek, Kathy; Pitcher, Ken; Stott, Jeffrey L.
Source:
EcoHealth 2006 v.3 no.2 pp. 109-113
ISSN:
1612-9202
Subject:
immune response,   etc   ; DNA; Eumetopias jubatus; animals; ecosystems; environmental health; gene expression; gene expression regulation; genotype; genotyping; major histocompatibility complex; messenger RNA; mononuclear leukocytes; nucleotide sequences; vigor; Alaska; Aleutian Islands;     Show all 17 Subjects
Abstract:
... Characterization of the polygenic and polymorphic features of the Steller sea lion major histocompatibility complex (MHC) provides an ideal window for evaluating immunologic vigor of the population and identifying emergence of new genotypes that reflect ecosystem pressures. MHC genotyping can be used to measure the potential immunologic vigor of a population. However, since ecosystem-induced chang ...
DOI:
10.1007/s10393-006-0021-0

70. Immune responses in Eimeria acervulina infected one-day-old broilers compared to amount of Eimeria in the duodenum, measured by real-time PCR

Author:
Swinkels, W.J.C.; Post, J.; Cornelissen, J.B.; Engel, B.; Boersma, W.J.A.; Rebel, J.M.J.
Source:
Veterinary parasitology 2006 v.138 no.3-4 pp. 223-233
ISSN:
0304-4017
Subject:
immune response,   etc   ; broiler chickens; duodenum; coccidiosis; messenger RNA; T-lymphocytes; lymphocyte proliferation; polymerase chain reaction; inoculum density; cytokines; Eimeria acervulina; chicks;     Show all 12 Subjects
DOI:
10.1016/j.vetpar.2006.02.011

71. Differential cytokine gene expression in CD4+ and CD8+ T cell subsets of calves

Author:
Tanaka, S.; Aso, H.; Miyazawa, K.; Nagai, Y.; Watanabe, K.; Ohwada, S.; Kobayashi, J.; Yamaguchi, T.
Source:
Veterinary immunology and immunopathology 2006 v.118 no.1-2 pp. 84-91
ISSN:
0165-2427
Subject:
immune response,   etc   ; messenger RNA; concanavalin A; interleukins; cell culture; lymphotoxin; granulocyte-macrophage colony-stimulating factor; gene expression; interferons; tumor necrosis factor-alpha; CD4-positive T-lymphocytes; transforming growth factor beta; calves; CD8-positive T-lymphocytes;     Show all 14 Subjects
Abstract:
... The distinct patterns of cytokine expression in CD4(+) and CD8(+) T cells are well understood in mice and humans. However, little information is available about cytokine expression in bovine CD4(+) and CD8(+) T cells. In this study, mRNA expression of 19 different cytokines was analyzed in CD4(+) and CD8(+) T cells of calves with or without Concanavalin A (Con A) stimulation. CD4(+) and CD8(+) T c ...
DOI:
10.1016/j.vetimm.2007.04.013

72. Differential expression of two glutathione S-transferases identified from the American dog tick, Dermacentor variabilis

Author:
Dreher-Lesnick, S.M.; Mulenga, A.; Simser, J.A.; Azad, A.F.
Source:
Insect molecular biology 2006 v.15 no.4 pp. 445-453
ISSN:
0962-1075
Subject:
immune response,   etc   ; Dermacentor variabilis; ticks; glutathione transferase; complementary DNA; nucleotide sequences; amino acid sequences; sequence homology; gene expression regulation; messenger RNA; tissue distribution; hematophagy;     Show all 12 Subjects
Abstract:
... Reciprocal signalling and gene expression play a cardinal role during pathogen-host molecular interactions and are prerequisite to the maintenance of balanced homeostasis. Gene expression repertoire changes during rickettsial infection and glutathione-S-transferases (GSTs) were among the genes found up-regulated in Rickettsia-infected Dermacentor variabilis. GSTs are well known to play an importan ...
DOI:
10.1111/j.1365-2583.2006.00657.x
PubMed:
16907831

73. Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease

Author:
Oyama, M.A.; Chittur, S.V.
Source:
American journal of veterinary research 2006 v.67 no.8 pp. 1307-1318
ISSN:
0002-9645
Subject:
immune response,   etc   ; dogs; pets; gene expression; genomics; heart valves; heart diseases; transcription (genetics); nucleotide sequences; messenger RNA; complementary DNA; microarray technology; gene expression regulation; biochemical pathways; pathophysiology; signal transduction; inflammation; extracellular matrix; metabolism;     Show all 19 Subjects
DOI:
10.2460/ajvr.67.8.1307
PubMed:
16881841

74. Identification and gene expression of the bovine C-type lectin Dectin-1

Author:
Willcocks, S.; Yamakawa, Y.; Stalker, A.; Coffey, T.J.; Goldammer, T.; Werling, D.
Source:
Veterinary immunology and immunopathology 2006 v.113 no.1-2 pp. 234-242
ISSN:
0165-2427
Subject:
immune response,   etc   ; cattle; lectins; receptors; gene expression; protein synthesis; outer membrane proteins; signal transduction; nucleotide sequences; amino acid sequences; chromosome mapping; isomers; messenger RNA; transcription (genetics); bone marrow; monocytes; macrophages; dendritic cells; natural killer cells; CD4-positive T-lymphocytes; B-lymphocytes; genes; genomics;     Show all 23 Subjects
Abstract:
... C-type lectin receptors (CTLR) are cell-surface signalling molecules that recognize a range of highly conserved pathogen molecules and instigate the appropriate immune response. Here, we report the cloning, sequencing, mapping and expression pattern of the bovine C-type lectin domain family 7, member A (CLEC7A; synonyms CLCSF12, Dectin-1). We identified two isoforms, similar to the human system, w ...
DOI:
10.1016/j.vetimm.2006.04.007

75. Mycotoxin fumonisin B1 selectively down-regulates the basal IL-8 expression in pig intestine: in vivo and in vitro studies

Author:
Bouhet, S.; Le Dorze, E.; Peres, S.; Fairbrother, J.M.; Oswald, I.P.
Source:
Food and chemical toxicology 2006 v.44 no.10 pp. 1768-1773
ISSN:
0278-6915
Subject:
immune response,   etc   ; in vivo studies; epithelial cells; interleukin-12; interleukin-8; Escherichia coli; messenger RNA; fumonisin B1; interleukin-1; ileum; Fusarium proliferatum; Fusarium fujikuroi; corn; lymphotoxin; feed contamination; bacterial colonization; toxigenic strains; food contamination; inflammation; interleukin-6; food pathogens; piglets;     Show all 22 Subjects
DOI:
10.1016/j.fct.2006.05.018
PubMed:
16843581

76. Escherichia coli Shiga toxin 1 enhances il-4 transcripts in bovine ileal intraepithelial lymphocytes

Author:
Moussay, E.; Stamm, I.; Taubert, A.; Balijer, G.; Menge, C.
Source:
Veterinary immunology and immunopathology 2006 v.113 no.3-4 pp. 367-382
ISSN:
0165-2427
Subject:
immune response,   etc   ; cattle; intestinal mucosa; cultured cells; Escherichia coli; animal pathogenic bacteria; Shiga toxin; lymphocytes; bacterial colonization; reverse transcriptase polymerase chain reaction; cytokines; messenger RNA; gene expression; protein synthesis;     Show all 14 Subjects
Abstract:
... Shiga toxin 1 (Stx1) blocks the activation of bovine peripheral and intraepithelial lymphocytes (IEL), implying that the toxin has the potential to retard the host's immune response during intestinal colonization of cattle with human pathogenic Stx-producing Escherichia coli (STEC). Since Stx1 does not eliminate affected lymphocytes by causing cellular death, we assumed that Stx1 disturbs the inte ...
DOI:
10.1016/j.vetimm.2006.06.007

77. Cytokine Expression in Chicken Peripheral Blood Mononuclear Cells after In Vitro Exposure to Salmonella enterica serovar Enteritidis

Author:
Kaiser, M.G.; Cheeseman, J.H.; Kaiser, P.; Lamont, S.J.
Source:
Poultry science 2006 v.85 no.11 pp. 1907-1911
ISSN:
0032-5791
Subject:
immune response,   etc   ; chickens; breed differences; messenger RNA; Salmonella Enteritidis; interleukins; lymphocytes; inflammation; transforming growth factor beta; in vitro studies; gene expression regulation;     Show all 11 Subjects
Abstract:
... Cytokines are secreted proteins involved with cell recruitment and regulation of both innate and adaptive immune responses. They are essential for an effective host immune response to pathogens. The objective of this study was to determine the effect of Salmonella enterica serovar Enteritidis (S. Enteritidis) exposure and genetic line on cytokine mRNA expression level of cultured chicken periphera ...
DOI:
10.1093/ps/85.11.1907
PubMed:
17032822

78. Cytokine and antibody subclass responses in the intestinal lymph of sheep during repeated experimental infections with the nematode parasite Trichostrongylus colubriformis

Author:
Pernthaner, A.; Cole, S.A.; Morrison, L.; Green, R.; Shaw, R.J.; Hein, W.R.
Source:
Veterinary immunology and immunopathology 2006 v.114 no.1-2 pp. 135-148
ISSN:
0165-2427
Subject:
immune response,   etc   ; lymph; messenger RNA; genetic resistance; Trichostrongylus colubriformis; interleukins; food animals; sheep; nematode infections; tumor necrosis factor-alpha; animal parasitic nematodes; intestines; immunoglobulins; genotype; gene expression; pest resistance; interferons;     Show all 17 Subjects
Abstract:
... The expression of interleukin (IL)-4, IL-5, IL-10, IL-13, TNF-α and IFN-γ genes, and parasite-specific IgM, IgG1, IgG2, IgA and total IgE levels, were monitored daily in intestinal lymph of sheep infected repeatedly with the nematode parasite Trichostrongylus colubriformis. Host genotype had a significant influence on IL-13 gene activity, with resistant-line (R) sheep consistently expressing highe ...
DOI:
10.1016/j.vetimm.2006.08.004

79. Quantitation of immune response gene expression and cellular localisation of interleukin-1β mRNA in Atlantic salmon, Salmo salar L., affected by amoebic gill disease (AGD)

Author:
Bridle, A.R.; Morrison, R.N.; Cunningham, P.M.C.; Nowak, B.F.
Source:
Veterinary immunology and immunopathology 2006 v.114 no.1-2 pp. 121-134
ISSN:
0165-2427
Subject:
immune response,   etc   ; Salmo salar; salmon; gene expression; quantitative analysis; interleukin-1; messenger RNA; protein synthesis; amebiasis; Amoebida; fish diseases; reverse transcriptase polymerase chain reaction; nucleic acid hybridization; genes; nitric oxide synthase; animal proteins; gills; liver; kidneys; gene expression regulation; infection;     Show all 21 Subjects
Abstract:
... The characterisation of selected immune response genes during amoebic gill disease (AGD) in Atlantic salmon, Salmo salar L., was performed using semi-quantitative RT-PCR, quantitative real-time RT-PCR (qRT-PCR), and in situ hybridisation (ISH). The immune response genes of interest were interleukin-1β (IL-1β), inducible nitric oxide synthase (iNOS), serum amyloid A (SAA), and serum amyloid P-like ...
DOI:
10.1016/j.vetimm.2006.08.002

80. The effect of tuberculin testing on the development of cell-mediated immune responses during Mycobacterium bovis infection

Author:
Thom, M.L.; Hope, J.C.; McAulay, M.; Villarreal-Ramos, B.; Coffey, T.J.; Stephens, S.; Vordermeier, H.M.; Howard, C.J.
Source:
Veterinary immunology and immunopathology 2006 v.114 no.1-2 pp. 25-36
ISSN:
0165-2427
Subject:
immune response,   etc   ; temporal variation; diagnostic techniques; immunoglobulin G; tuberculin; messenger RNA; disease course; serodiagnosis; interleukins; protein synthesis; Mycobacterium bovis; gene expression; bovine tuberculosis; delayed hypersensitivity; calves; lymphocyte proliferation; interferons;     Show all 17 Subjects
Abstract:
... Protection against tuberculosis (TB) is associated with Th1-type cell-mediated immunity (CMI). Whilst the intradermal injection of partially purified derivatives of tuberculin (PPD) represents the classic test assessing the delayed type hypersensitivity (DTH) response used in both humans and cattle for diagnosing TB, it has been suggested that the test may modulate host CMI responses. To investiga ...
DOI:
10.1016/j.vetimm.2006.07.001

81. The feathering gene is linked to degranulation and oxidative burst not cytokine/chemokine mRNA expression levels or Salmonella enteritidis organ invasion in broilers

Author:
Swaggerty, C.L.; He, H.Q.; Genovese, K.J.; Kaiser, P.; Pevzner, I.Y.; Kogut, M.H.
Source:
Avian pathology 2006 v.35 no.6 pp. 465-470
ISSN:
0307-9457
Subject:
immune response,   etc   ; chickens; in vivo studies; messenger RNA; infection; Salmonella Enteritidis; interleukins; sex linkage; poultry diseases; reciprocal crosses; gene expression; salmonellosis; animal organs; disease resistance; oxidation; feathers; heterophils; animal genetics;     Show all 18 Subjects
DOI:
10.1080/03079450601028829
PubMed:
17121735

82. Cytokine expression in leucocytes and gut cells of rainbow trout, Oncorhynchus mykiss Walbaum, induced by probiotics

Author:
Kim, D.H.; Austin, B.
Source:
Veterinary immunology and immunopathology 2006 v.114 no.3-4 pp. 297-304
ISSN:
0165-2427
Subject:
immune response,   etc   ; veterinary medicine; cytokines; leukocytes; enterocytes; trout; Oncorhynchus mykiss; probiotics; messenger RNA;     Show all 9 Subjects
Abstract:
... Understanding how the various host cells respond to probiotic bacteria in vitro may provide important insight into elaborate immune responses triggered by beneficial bacteria. The aim of this study was to investigate the detailed pattern of the mRNA expression of cytokines (IL-1β, IL-8, TNF-α and TGF-β) in head kidney (HK) leucocytes and gut cells isolated from rainbow trout (Oncorhynchus mykiss W ...
DOI:
10.1016/j.vetimm.2006.08.015

83. Dynamics of transcription of immunomodulatory genes in endothelial cells infected with different coccidian parasites

Author:
Taubert, A.; Zahner, H.; Hermosilla, C.
Source:
Veterinary parasitology 2006 v.142 no.3-4 pp. 214-222
ISSN:
0304-4017
Subject:
immune response,   etc   ; messenger RNA; coccidiosis; endothelial cells; cattle; Neospora caninum; gene expression regulation; transcription (genetics); immunologic factors; Eimeria bovis; Toxoplasma gondii; infection;     Show all 12 Subjects
DOI:
10.1016/j.vetpar.2006.07.021

84. Leishmania DNA load and cytokine expression levels in asymptomatic naturally infected dogs

Author:
Manna, L.; Reale, S.; Viola, E.; Vitale, F.; Manzillo, V.F.; Michele, P.L.; Caracappa, S.; Gravino, A.E.
Source:
Veterinary parasitology 2006 v.142 no.3-4 pp. 271-280
ISSN:
0304-4017
Subject:
immune response,   etc   ; messenger RNA; disease course; interleukins; DNA; dogs; polymerase chain reaction; Leishmania infantum; gene expression; visceral leishmaniasis; parasitemia; interferons;     Show all 12 Subjects
DOI:
10.1016/j.vetpar.2006.06.028

85. Comparison of the Human and Canine Cytokines IL-1(α/β) and TNF-α to Orthologous Other Mammalians

Author:
Soller, Jan T.; Murua-Escobar, Hugo; Willenbrock, Saskia; Janssen, Miriam; Eberle, Nina; Bullerdiek, Jörn; Nolte, Ingo
Source:
Journal of heredity 2007 v.98 no.5 pp. 485-490
ISSN:
0022-1503
Subject:
immune response,   etc   ; Alzheimer disease; Parkinson disease; amino acid sequences; cats; cattle; dog diseases; dogs; genes; genetic background; histiocytosis; horses; humans; inflammation; interleukin-1beta; messenger RNA; metabolic diseases; mice; models; necrosis; neoplasms; nucleotide sequences; pathogenesis; proteins; rats; rheumatoid arthritis; sheep; swine; tumor necrosis factor-alpha;     Show all 29 Subjects
Abstract:
... The cytokines interleukin-1 (IL-1α and IL-1β) and the tumor necrosis factor-α (TNF-α) both play a major role in the initiation and regulation of inflammation and immunity responses. Polymorphisms within the gene sequences of these cytokines IL-1 and TNF-α have been proposed to play an important role in the pathogenesis of certain diseases. Affecting nearly every organ, various diseases, including ...
DOI:
10.1093/jhered/esm025

86. Long-Term Staphylococcal Enterotoxin C1 Exposure Induces Soluble Factor-Mediated Immunosuppression by Bovine CD4⁺ and CD8⁺ T Cells

Author:
Seo, Keun Seok; Lee, Sang Un; Park, Yong Ho; Davis, William C.; Fox, Lawrence K.; Bohach, Gregory A.
Source:
Infection and immunity 2007 v.75 no.1 pp. 260-269
ISSN:
0019-9567
Subject:
immune response,   etc   ; Staphylococcus aureus; T-lymphocytes; cattle; gene expression regulation; genes; immune evasion; interleukin-10; interleukin-2; messenger RNA; pathogens; superantigens; transforming growth factor beta;     Show all 13 Subjects
Abstract:
... Regulatory T cells (Tregs) help control the development and maintenance of protective immunity and can lead to aberrant immune responses to some pathogens. Several lines of evidence suggest that Tregs are induced by exposure to superantigens (SAgs) in vitro or in vivo. In this study, bovine peripheral blood mononuclear cells (PBMC) were exposed in vitro to a relatively low dose (5 ng/ml) of staphy ...
DOI:
10.1128/IAI.01358-06

87. Changes in Morphology and Key Cytokine Gene Expression after Intradermal Injection of Louse (Bovicola ovis) Antigen in Sheep with Naturally Occurring Atopic Dermatitis

Author:
Pfeffer, A.; Wilson, J.A.; Pernthaner, A.
Source:
Journal of comparative pathology 2007 v.136 no.1 pp. 36-48
ISSN:
0021-9975
Subject:
immune response,   etc   ; messenger RNA; antigens; gene expression; injection; eosinophils; lambs; atopic dermatitis; interleukin-4; Bovicola ovis; lice infestations; interferons;     Show all 12 Subjects
DOI:
10.1016/j.jcpa.2006.10.004
PubMed:
17270203

88. Lamellar pro-inflammatory cytokine expression patterns in laminitis at the developmental stage and at the onset of lameness: innate vs. adaptive immune response

Author:
Belknap, J.K.; Giguere, S.; Pettigrew, A.; Cochran, A.M.; Van Eps, A.W.; Pollitt, C.C.
Source:
Equine veterinary journal 2007 v.39 no.1 pp. 42-47
ISSN:
0425-1644
Subject:
immune response,   etc   ; messenger RNA; protein synthesis; disease models; interleukins; laminitis; polymerase chain reaction; inflammation; lameness; quantitative genetics; laminae (animals); gene expression; tumor necrosis factor-alpha; interferons; horses; disease course;     Show all 16 Subjects
PubMed:
17228594

89. Matrix metalloproteinase mRNA expression in canine anal furunculosis lesions

Author:
House, A.K.; Catchpole, B.; Gregory, S.P.
Source:
Veterinary immunology and immunopathology 2007 v.115 no.1-2 pp. 68-75
ISSN:
0165-2427
Subject:
immune response,   etc   ; metalloproteinases; messenger RNA; gene expression; dogs; dog diseases; anus; furunculosis; lesions (animal); cytokines; cyclosporins; inflammation; T-lymphocytes;     Show all 13 Subjects
Abstract:
... Although the aetiology of anal furunculosis (AF) in dogs is poorly understood, there is evidence for an underlying immune dysfunction. This is illustrated by the presence of a T helper type 1 cytokine mRNA profile in AF lesions and the clinical response to ciclosporin therapy. Expression of MMPs 2, 9 and 13 were evaluated in AF lesional biopsies by real-time quantitative RT-PCR. There was signific ...
DOI:
10.1016/j.vetimm.2006.10.018

90. Use and relevance of a bovine mammary gland explant model to study infection responses in bovine mammary tissue

Author:
Rabot, A.; Wellnitz, O.; Meyer, H.H.D.; Bruckmaier, R.M.
Source:
Journal of dairy research 2007 v.74 no.1 pp. 93-99
ISSN:
0022-0299
Subject:
immune response,   etc   ; dairy cows; messenger RNA; disease models; lipopolysaccharides; lactalbumin; interleukins; explants; immunomodulators; tumor necrosis factor-alpha; immunoglobulins; gene expression; mammary glands; bovine mastitis; animal tissues;     Show all 15 Subjects
Abstract:
... Our aim was to develop an explant model to define more precisely the early response of bovine mammary epithelial cells to infection. Therefore we investigated the mRNA expression encoding for some soluble immunological factors in lipopolysaccharide (LPS)-treated bovine mammary gland explants. Explants were taken out from the mammary gland of eight lactating cows after slaughter then incubated with ...
DOI:
10.1017/S0022029906002147
PubMed:
16978438

91. Effect of Yak Milk Casein Hydrolysate on Th1/Th2 Cytokines Production by Murine Spleen Lymphocytes in Vitro

Author:
Mao, X.Y.; Yang, H.Y.; Song, J.P.; Li, Y.H.; Ren, F.Z.
Source:
Journal of agricultural and food chemistry 2007 v.55 no.3 pp. 638-642
ISSN:
0021-8561
Subject:
immune response,   etc   ; maternal milk; yaks; casein hydrolysates; dairy products; T-lymphocytes; lymphocyte proliferation; splenocytes; interleukin-2; gene expression; messenger RNA; interleukin-4; interferons; cell cycle; rats;     Show all 15 Subjects
Abstract:
... Yak casein hydrolysate was derived from the enzymatic alcalase-hydrolysate of a typical northwestern China milk product called Qula. An in vitro study was conducted to examine their immunoregulatory effects on murine T cells, including Con-A-induced lymphoproliferation and splenocyte cell cycle, production, and messenger RNA (mRNA) expression of interleukin-2 (IL-2), interferon-γ (IFN-γ), and inte ...
DOI:
10.1021/jf062452m

92. Expression of Toll-like receptors, interleukin 8, macrophage migration inhibitory factor, and osteopontin in tissues from pigs challenged with Salmonella enterica serovar Typhimurium or serovar Choleraesuis

Author:
Burkey, T.E.; Skjolaas, K.A.; Dritz, S.S.; Minton, J.E.
Source:
Veterinary immunology and immunopathology 2007 v.115 no.3-4 pp. 309-319
ISSN:
0165-2427
Subject:
immune response,   etc   ; messenger RNA; Salmonella choleraesuis Choleraesuis; secretion; swine diseases; Salmonella Typhimurium; interleukin-8; signal transduction; macrophages; tissue distribution; salmonellosis; osteopontin; pathogenesis; receptors; strains; animal tissues; swine;     Show all 17 Subjects
Abstract:
... Two serovars of Salmonella enterica, namely serovar Typhimurium (ST) and serovar Choleraesuis (SC) account for the vast majority of clinical cases of swine salmonellosis worldwide. These serovars are thought to be transmitted among pigs in production settings mainly through fecal-oral routes. Yet, few studies have evaluated effects of these serovars on expression of innate immune targets when pres ...
DOI:
10.1016/j.vetimm.2006.11.012

93. Porcine circovirus type 2 (PCV2) distribution and replication in tissues and immune cells in early infected pigs

Author:
Yu, S.; Opriessnig, T.; Kitikoon, P.; Nilubol, D.; Halbur, P.G.; Thacker, E.
Source:
Veterinary immunology and immunopathology 2007 v.115 no.3-4 pp. 261-272
ISSN:
0165-2427
Subject:
immune response,   etc   ; epidemiological studies; in vivo studies; messenger RNA; antigen detection; monocytes; capsid; DNA; tissue distribution; reverse transcriptase polymerase chain reaction; immunologic factors; animal tissues; pathogenesis; Porcine circovirus; B-lymphocytes; virus replication; postweaning multisystemic wasting syndrome; swine;     Show all 18 Subjects
Abstract:
... Replication of porcine circovirus type 2 (PCV2) in pigs, as measured by spliced capsid mRNA (Cap mRNA) and viral DNA, was investigated following experimental infection. Peripheral blood mononuclear cells (PBMCs), and tissue from bronchial lymph nodes (BLN), inguinal lymph nodes (ILN), tonsils, lungs, liver, kidneys, spleen and thymus from infected pigs on different days post-infection (DPI) were a ...
DOI:
10.1016/j.vetimm.2006.11.006

94. Proinflammatory cytokine mRNA expression in mammary tissue of sows following intramammary inoculation with Escherichia coli

Author:
Zhu, Y.; Berg, M.; Fossum, C.; Magnusson, U.
Source:
Veterinary immunology and immunopathology 2007 v.116 no.1-2 pp. 98-103
ISSN:
0165-2427
Subject:
immune response,   etc   ; correlation; mastitis; protein synthesis; tumor necrosis factors; messenger RNA; interleukins; swine diseases; sows; parturition; mammary glands; inflammation; gene expression; immune system; Escherichia infections; signs and symptoms (animals and humans); Escherichia coli;     Show all 17 Subjects
Abstract:
... The expression of the proinflammatory cytokines interleukin-1β (IL-1β), IL-6, IL-8, and tumor necrosis factor-α (TNF-α) mRNAs was determined by reverse transcription-PCR (RT-PCR) analysis of biopsies from the mammary glands of sows. The biopsies were collected before and 24 h after intramammary inoculation of 12 pregnant sows with Escherichia coli (E. coli). Four of the sows developed clinical sig ...
DOI:
10.1016/j.vetimm.2006.12.003

95. Cytokine and Chemokine Gene Expression of IL-1β Stimulated Equine Articular Chondrocytes [Erratum: 2008 July, v. 37, issue 5, p. 499.]

Author:
DAVID, FLORENT; FARLEY, JUDITH; HUANG, HONG; LAVOIE, JEAN-PIERRE; LAVERTY, SHEILA
Source:
Veterinary surgery 2007 v.36 no.3 pp. 221-227
ISSN:
0161-3499
Subject:
immune response,   etc   ; pathophysiology; etiology; anti-inflammatory activity; messenger RNA; in vitro studies; interleukin-1; cell culture; inflammation; cell physiology; biochemical pathways; gene expression; cartilage; tumor necrosis factor-alpha; immune system; horse diseases; osteoarthritis; horses; chondrocytes;     Show all 19 Subjects
Abstract:
... To evaluate mRNA expression of several proinflammatory and anti-inflammatory cytokines and chemokines in equine unstimulated and interleukin-1β (IL-1β)-stimulated chondrocytes. In vitro experiment using equine chondrocyte cultures. Whole articular cartilage from metacarpophalangeal joints (n=5 horses; 10 fetlocks). Chondrocyte monolayer cultures were established from digested adult equine articula ...
DOI:
10.1111/j.1532-950X.2007.00253.x

96. Effect of lactoferrin on selected immune system parameters and the gastrointestinal morphology in growing calves

Author:
Prgomet, C.; Prenner, M.L.; Schwarz, F.J.; Pfaffl, M.W.
Source:
Journal of animal physiology and animal nutrition 2007 v.91 no.3-4 pp. 109-119
ISSN:
0931-2439
Subject:
immune response,   etc   ; Peyer's patches; average daily intake; blood serum; calves; epithelial cells; gene expression; genetic markers; glycoproteins; granules; ileum; immunoglobulin G; in vivo studies; interferon-gamma; interleukin-10; interleukin-1beta; interleukin-8; jejunum; lactoferrin; messenger RNA; milk; milk replacer; neutrophils; villi;     Show all 24 Subjects
Abstract:
... Lactoferrin (LF) is a cationic iron-binding glycoprotein that is abundantly expressed and secreted from glandular epithelial cells and a prominent component of the secondary granules of polymorphonuclear neutrophils. Various in vitro and in vivo experiments demonstrate anti-microbial, -viral, -mycotic and -inflammatory effects of LF, associated with modulations of the immune system. Effects of ora ...
DOI:
10.1111/j.1439-0396.2006.00649.x

97. Evaluation of stress- and immune-response biomarkers in Atlantic salmon, Salmo salar L., fed different levels of genetically modified maize (Bt maize), compared with its near-isogenic parental line and a commercial suprex maize

Author:
Sagstad, A.; Sanden, M.; Haugland, Ø.; Hansen, A-C.; Olsvik, P.A.; Hemre, G-I.
Source:
Journal of fish diseases 2007 v.30 no.4 pp. 201-212
ISSN:
0140-7775
Subject:
immune response,   etc   ; Bacillus thuringiensis; Salmo salar; biomarkers; catalase; corn; diet; fish; fish health; gene expression; granulocytes; heat-shock protein 70; interleukin-1beta; intestines; kidneys; liver; lymphocytes; messenger RNA; monocytes; spleen; starch; superoxide dismutase; transgenic plants;     Show all 23 Subjects
Abstract:
... The present study was designed to evaluate if genetically modified (GM) maize (Bt maize, event MON810) compared with the near-isogenic non-modified (nGM) maize variety, added as a starch source at low or high inclusions, affected fish health of post-smolt Atlantic salmon, Salmo salar L. To evaluate the health impact, selected stress- and immune-response biomarkers were quantified at the gene trans ...
DOI:
10.1111/j.1365-2761.2007.00808.x
PubMed:
17394522

98. Impairment of innate immune responses of airway epithelium by infection with bovine viral diarrhea virus

Author:
Al-Haddawi, M.; Mitchell, G.B.; Clark, M.E.; Wood, R.D.; Caswell, J.L.
Source:
Veterinary immunology and immunopathology 2007 v.116 no.3-4 pp. 153-162
ISSN:
0165-2427
Subject:
immune response,   etc   ; messenger RNA; protein synthesis; lipopolysaccharides; immunosuppression; cell culture; cattle; mucosal immunity; epithelial cells; bovine viral diarrhea; pneumonic pasteurellosis; antimicrobial peptides; Mannheimia haemolytica; Bovine viral diarrhea virus 1; trachea (vertebrates); lactoferrin; mixed infection;     Show all 17 Subjects
Abstract:
... Bovine viral diarrhea virus (BVDV) infection is an important risk factor for development of shipping fever pneumonia in feedlot cattle, and infects but does not cause morphologic evidence of damage to airway epithelial cells. We hypothesized that BVDV predisposes to bacterial pneumonia by impairing innate immune responses in airway epithelial cells. Primary cultures of bovine tracheal epithelial c ...
DOI:
10.1016/j.vetimm.2007.01.007

99. Identification of Marker Genes for Intestinal Immunomodulating Effect of a Fructooligosaccharide by DNA Microarray Analysis

Author:
Fukasawa, T.; Murashima, K.; Matsumoto, I.; Hosono, A.; Ohara, H.; Nojiri, C.; Koga, J.; Kubota, H.; Kanegae, M.; Kaminogawa, S.
Source:
Journal of agricultural and food chemistry 2007 v.55 no.8 pp. 3174-3179
ISSN:
0021-8561
Subject:
immune response,   etc   ; prebiotics; fructooligosaccharides; food intake; gene expression; messenger RNA; microarray technology; ileum; interferons; phosphatidylinositols; major histocompatibility complex; Peyer's patches; mice; genetic markers;     Show all 14 Subjects
Abstract:
... Prebiotic fructooligosaccharides are noted for their intestinal immunodulating effects, and the identification of markers for the effects is a matter of great concern. This study aimed to identify marker genes for physiological effects of a particular fructooligosaccharide (FOS) on a host animal and also to define the target of its function in the small intestine. DNA microarray technology was use ...
DOI:
10.1021/jf062814q

100. Effect of bovine colostrum supplementation on cytokine mRNA expression in weaned piglets

Author:
Boudry, C.; Buldgen, A.; Portetelle, D.; Gianello, P.; Théwis, A.; Leterme, P.; Dehoux, J.P.
Source:
Livestock science 2007 v.108 no.1-3 pp. 295-298
ISSN:
1878-0490
Subject:
immune response,   etc   ; messenger RNA; weanlings; interleukins; inflammation; disease prevention; immunomodulators; cow colostrum; dosage; gene expression; Peyer's patches; jejunum; reverse transcriptase polymerase chain reaction; lymph nodes; spleen; feed supplements; piglets; interferons;     Show all 18 Subjects
DOI:
10.1016/j.livsci.2007.01.088