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- Roychowdhury, Sanjoy, et al. Show all 7 Authors
- Molecular Immunology 2016 v.75 pp. 122-132
- alanine transaminase; apoptosis; complement; cytotoxicity; diet; ethanol; hepatocytes; inflammation; liver; liver diseases; mice; triacylglycerols; tumor necrosis factor-alpha
- ... Complement is implicated in the development of alcoholic liver disease. C3 and C5 contribute to ethanol-induced liver injury; however, the role of C5a receptor (C5aR) on myeloid and non-myeloid cells to progression of injury is not known.C57BL/6 (WT), global C5aR-/-, myeloid-specific C5aR-/-, and non-myeloid-specific C5aR-/- mice were fed a Lieber-DeCarli diet (32%kcal EtOH) for 25 days. Cultured ...
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