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- Mi, Sha, et al. Show all 13 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2007 v.104 no.36 pp. 14430-14435
- Parkinson disease; animal models; antagonists; antibodies; brain; disease models; epidermal growth factor receptors; humans; knockout mutants; mice; neurites; neuroprotective effect; neurotoxicity; patients; phosphorylation; signal transduction; tyrosine
- ... The nervous system-specific leucine-rich repeat Ig-containing protein LINGO-1 is associated with the Nogo-66 receptor complex and is endowed with a canonical EGF receptor (EGFR)-like tyrosine phosphorylation site. Our studies indicate that LINGO-1 expression is elevated in the substantia nigra of Parkinson's disease (PD) patients compared with age-matched controls and in animal models of PD after ...
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