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- Rossig, Claudia, et al. Show all 31 Authors
- Cell 2013 v.152 pp. 1065-1076
- antineoplastic agents; brain; cell viability; metastasis; mice; morbidity; neoplasm cells; patients; toxicity; vascular endothelial growth factor receptors
- ... Medulloblastoma is the most common pediatric malignant brain tumor. Although current therapies improve survival, these regimens are highly toxic and are associated with significant morbidity. Here, we report that placental growth factor (PlGF) is expressed in the majority of medulloblastomas, independent of their subtype. Moreover, high expression of PlGF receptor neuropilin 1 (Nrp1) correlates wi ...
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