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You searched for: Author "Martins, Nathan Dias" Remove constraint Author: "Martins, Nathan Dias" Subject oxidation Remove constraint Subject: oxidation
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1. Microcystin – LR exposure causes cardiorespiratory impairments and tissue oxidative damage in trahira, Hoplias malabaricus

Author:
Martins, Nathan Dias,   et al.   ; Yunes, João Sarkis; Mckenzie, David J.; Rantin, Francisco Tadeu; Kalinin, Ana Lúcia; Monteiro, Diana Amaral;     Show all 6 Authors
Source:
Ecotoxicology and environmental safety 2019 v.173 pp. 436-443
ISSN:
0147-6513
Subject:
Hoplias malabaricus; antioxidant activity; biomarkers; cardiorespiratory fitness; catalase; enzyme activity; freshwater fish; gills; glutathione; glutathione peroxidase; glutathione transferase; heart rate; intraperitoneal injection; lipid peroxidation; liver; microcystin-LR; oxidation; oxidative stress; oxygen; protein content; proteins; superoxide dismutase; tidal volume; toxicity
Abstract:
... This study investigated the effect of microcystin-LR (MC-LR) on in vivo cardiorespiratory function and on tissue biomarkers of oxidative stress in gills and liver of the trahira, a neotropical freshwater fish. Trahira were treated with an intraperitoneal injection of 100 µg MC-LR.kg−1 body mass or a saline, with the toxic effects of MC-LR then evaluated after 48 h. Rates of oxygen uptake (V̇O2) di ...
DOI:
10.1016/j.ecoenv.2019.02.053

2. Microcystin-LR leads to oxidative damage and alterations in antioxidant defense system in liver and gills of Brycon amazonicus (SPIX & AGASSIZ, 1829)

Author:
Martins, Nathan Dias,   et al.   ; Yunes, João Sarkis; Monteiro, Diana Amaral; Rantin, Francisco Tadeu; Kalinin, Ana Lúcia;     Show all 5 Authors
Source:
Toxicon 2017
ISSN:
0041-0101
Subject:
Brycon amazonicus; Cyanobacteria; antioxidant activity; antioxidants; cell death; cytoskeleton; fish; gills; humans; liver; microcystin-LR; oxidation; oxidative stress; superoxide dismutase; surface water; toxicity
Abstract:
... Microcystin's (MCs) are toxins produced by several groups of cyanobacteria, in water bodies throughout the world, in a process which is being intensified by human action. Among the variants of MCs, MC-LR stands out for its distribution and toxicity. MCs are potent inhibitors of protein phosphatases 1 and 2 A, which causes disruption of the cytoskeleton and consequent cell death. They can also alte ...
DOI:
10.1016/j.toxicon.2017.10.006