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You searched for: Author "Shaheen, Hazem" Remove constraint Author: "Shaheen, Hazem" Subject oxidative stress Remove constraint Subject: oxidative stress
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1. Putative impacts of phytogenic additives to ameliorate lead toxicity in animal feed

Author:
Shaheen, Hazem,   et al.   ; Abd El-Hack, Mohamed E.; Abdelnour, Sameh A.; Abd El-Moneim, Abd El-Moneim E.; Arif, Muhammad; Khafaga, Asmaa; Samak, Dalia; Swelum, Ayman A.;     Show all 8 Authors
Source:
Environmental science and pollution research international 2019 v.26 no.23 pp. 23209-23218
ISSN:
0944-1344
Subject:
additives; animal models; animals; anthropogenic activities; antioxidants; chronic exposure; epithelium; feeds; health status; heavy metals; hepatocytes; hypertrophy; lead; liver; necrosis; oxidative stress; poisoning; pollutants; renal tubules; risk; spermatocytes; testes; toxicity; working conditions
Abstract:
... Lead (Pb) is a toxic heavy metal and an environmental pollutant, particularly because of its anthropogenic activity. The main impacts of Pb is recognized to cause injurious influences of various levels of the tropic chain, due to bio-accumulated lead causes many health issues such as intoxication of different body organs, such as kidneys and liver, and reproductive and nervous systems. Industrial ...
DOI:
10.1007/s11356-019-05805-8

2. Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats

Author:
Shaheen, Hazem M.,   et al.   ; Abdel-Daim, Mohamed M.; Abushouk, Abdelrahman Ibrahim; Toraih, Eman A.; Fawzy, Manal S.; Alansari, Wafa S.; Aleya, Lotfi; Bungau, Simona;     Show all 8 Authors
Source:
Environmental science and pollution research international 2018 v.25 no.24 pp. 23909-23916
ISSN:
0944-1344
Subject:
alanine; albumins; alkaline phosphatase; antioxidant activity; antioxidants; aspartic acid; blood serum; brain; catalase; cholesterol; creatinine; diallyl sulfides; fipronil; gamma-glutamyltransferase; glutathione; glutathione peroxidase; insecticides; laboratory animals; lactate dehydrogenase; males; malondialdehyde; nitric oxide; oxidative stress; rats; superoxide dismutase; tissues; toxicity; triacylglycerols; urea; uric acid
Abstract:
... Fipronil (FPN) is a phenylpyrazole insecticide, widely used for agricultural and veterinary activities. Early reports indicated that FIP organ toxicity is primarily mediated by the induction of oxidative stress. Both thymoquinone (TQ) and diallyl sulfide (DAS) are natural antioxidants with established health benefits. This study investigated the potential ameliorative effects of DAS and TQ against ...
DOI:
10.1007/s11356-018-2386-3

3. The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice

Author:
Shaheen, Hazem M.,   et al.   ; Onoda, Atsuto; Shinkai, Yusuke; Nakamura, Masayuki; El-Ghoneimy, Ashraf A.; El-Sayed, Yasser S.; Takeda, Ken; Umezawa, Masakazu;     Show all 8 Authors
Source:
Ecotoxicology and environmental safety 2016 v.132 pp. 390-396
ISSN:
0147-6513
Subject:
air pollution; biomarkers; biosynthesis; body weight; breathing; ceramides; epithelial cells; fumonisin B1; gene expression; inflammation; males; messenger RNA; mice; oxidative stress
Abstract:
... Recent studies have suggested that inhalation of diesel exhaust (DE), a major source of air pollution, results in pulmonary alterations; however, the effects of DE at low concentrations are poorly understood. Therefore, this study was conducted to elucidate the pulmonary effects of low-level exposure to DE and the potential role of a ceramide de novo biosynthesis inhibitor, fumonisin B1 (FB1) to a ...
DOI:
10.1016/j.ecoenv.2016.06.025