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- Urbani, Andrea, et al. Show all 11 Authors
- Journal of chromatography 2019 v.1124 pp. 165-172
- Alzheimer disease; G-proteins; brain; diet; disease models; genotype; liquid chromatography; mass spectrometry; metallothionein; mice; peptides; proteome; proteomics; vitamin B complex
- ... The multifactorial nature of Late Onset Alzheimer's Disease (LOAD), the AD form of major relevance on epidemiological and social aspects, has driven the original investigation by LC-MS and top-down proteomics approach of the protein repertoire of the brain tissue of TgCRND8 model mice fed with a diet deficient in B vitamins. The analysis of the acid-soluble fraction of brain tissue homogenates ide ...