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41. Cell death induced by sodium nitroprusside and hydrogen peroxide in tobacco BY-2 cell suspension

Author:
Víteček, J.; Wünschová, A.; Petřek, J.; Adam, V.; Kizek, R.; Havel, L.
Source:
Biologia plantarum 2007 v.51 no.3 pp. 472-479
ISSN:
0006-3134
Subject:
perfluorocarbons,   etc   ; DNA fragmentation; Nicotiana tabacum; apoptosis; chromatin; esterases; glucose; glucose oxidase; hydrogen peroxide; nitric oxide; nitroprusside; potassium; tobacco; toxicity; vacuoles;     Show all 15 Subjects
Abstract:
... The interplay between nitric oxide (NO) and reactive oxygen species can lead to an induction of cell death in plants. The aim of our work was to find out if cyanide released from sodium nitroprusside (SNP; a donor of NO) could be involved in the cell death induction, which is triggered by SNP and H₂O₂. Cell suspension of Nicotiana tabacum L. (line BY-2) was treated with 0.5 mM SNP, 0.5 mM potassiu ...
DOI:
10.1007/s10535-007-0099-4

42. Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine

Author:
Kargieman, Lucila; Santana, Noemí; Mengod, Guadalupe; Celada, Pau; Artigas, Francesc
Source:
Proceedings of the National Academy of Sciences of the United States of America 2007 v.104 no.37 pp. 14843-14848
ISSN:
0027-8424
Subject:
perfluorocarbons,   etc   ; antagonists; antipsychotics; cognition; cortex; dopamine receptors; haloperidol; models; neurons; rats; schizophrenia; thalamus; therapeutics;     Show all 13 Subjects
Abstract:
... NMDA receptor (NMDA-R) antagonists are extensively used as schizophrenia models because of their ability to evoke positive and negative symptoms as well as cognitive deficits similar to those of the illness. Cognitive deficits in schizophrenia are associated with prefrontal cortex (PFC) abnormalities. These deficits are of particular interest because an early improvement in cognitive performance p ...
DOI:
10.1073/pnas.0704848104
PubMed:
17785415
PubMed Central:
PMC1976198

43. Perfluorinated Compounds in River Water, River Sediment, Market Fish, and Wildlife Samples from Japan

Author:
Senthilkumar, Kurunthachalam; Ohi, Etsumasa; Sajwan, Kenneth; Takasuga, Takumi; Kannan, Kurunthachalam
Source:
Bulletin of environmental contamination and toxicology 2007 v.79 no.4 pp. 427-431
ISSN:
0007-4861
Subject:
perfluorocarbons,   etc   ; Nyctereutes procyonoides; Phalacrocorax; crows; eagles; liver; mackerel; markets; river water; rivers; sediments; wildlife; Japan;     Show all 13 Subjects
Abstract:
... Perfluorinated organic compounds (PFCs) such as PFOS, PFOA, PFBS, PFHxS, PFOSA and PFDoA were determined in river water, river sediment, liver of market fish and liver of wildlife samples from Japan. Concentrations of PFOA and PFOS in water samples were 7.9-110 and <5.2-10 ng/L. Only PFOA were detected in sediment from Kyoto river at 1.3-3.9 ng/g dry wt. Among fish, only jack mackerel showed PFOA ...
DOI:
10.1007/s00128-007-9243-2
PubMed:
17634852

44. Determination of dimethylarginine levels in rats using HILIC-MS/MS: An in vivo microdialysis study

Author:
Zotti, Margherita; Schiavone, Stefania; Tricarico, Filomena; Colaianna, Marilena; D'Apolito, Oceania; Paglia, Giuseppe; Corso, Gaetano; Trabace, Luigia
Source:
Journal of separation science 2008 v.31 no.13 pp. 2511-2515
ISSN:
1615-9306
Subject:
perfluorocarbons,   etc   ; cerebrospinal fluid; chromatography; cortex; hydrophilic interactions; isomers; nitric oxide; nitric oxide synthase; rats; urine;     Show all 10 Subjects
Abstract:
... Nitric oxide (NO) is one of the most important mediators and neurotransmitters and its levels change under pathological conditions. NO production may be regulated by endogenous nitric oxide synthase (NOS) inhibitors, in particular asymmetric dimethylarginine (ADMA). Most of the interest is focused on ADMA, since this compound is present in plasma and urine and accumulation of ADMA has been describ ...
DOI:
10.1002/jssc.200800147
PubMed:
18604843

45. Immunomodulatory activity of biopolymeric fraction BOS 2000 from Boswellia serrata

Author:
Khajuria, Anamika; Gupta, Amit; Suden, Pankaj; Singh, Surjeet; Malik, Fayaz; Singh, Jaswant; Gupta, B.D.; Suri, K.A.; Srinivas, V.K.; Ella, Krishna; Qazi, G.N.
Source:
Phytotherapy research 2008 v.22 no.3 pp. 340-348
ISSN:
0951-418X
Subject:
perfluorocarbons,   etc   ; Boswellia serrata; T-lymphocytes; antibodies; biopolymers; complement; delayed hypersensitivity; dose response; immunoglobulin G; immunoglobulin M; lymphocyte proliferation; macrophage activation; mechanism of action; mice; nitrites; oral administration;     Show all 16 Subjects
Abstract:
... Oral administration of BOS 2000 (1-10 mg/kg) elicited a dose related increase in the delayed hypersensitivity reaction (early 24 h and delayed 48 h) in mice. It also stimulated the IgM and IgG titre expressed in the form of plaques (PFC) and complement fixing antibody titre. The concentration of cytokines (IL-4, IFN-γ and TNF-α) in serum with respect to T cell interactions, i.e. (CD4/CD8) and the ...
DOI:
10.1002/ptr.2320
PubMed:
18167047

46. Layer structure estimation of three-dimensional crystal and two-dimensional molecular film for fluorinated comb copolymers Part B Polymer physics

Author:
Fujimori, Atsuhiro; Hoshizawa, Hiroko; Kobayashi, Satoshi; Kanai, Kaname; Ouchi, Yukio; Seki, Kazuhiko
Source:
Journal of polymer science 2008 v.46 no.5 pp. 534-546
ISSN:
0887-6266
Subject:
perfluorocarbons,   etc   ; X-radiation; X-ray diffraction; adsorption; composite polymers; crystal structure; spectroscopy;     Show all 7 Subjects
Abstract:
... Comb copolymers containing both hydrogenated and fluorinated side-chains were prepared by copolymerization using acrylic or methacrylic monomers in several ratios. The crystal structures of these copolymers and layer structures of their organized molecular films were investigated by wide-angle X-ray diffraction (WAXD), small-angle X-ray scattering (SAXS), and out-of plane X-ray diffraction. Furthe ...
DOI:
10.1002/polb.21387

47. Transient and selective overexpression of D₂ receptors in the striatum causes persistent deficits in conditional associative learning

Author:
Bach, Mary-Elizabeth; Simpson, Eleanor H.; Kahn, Lora; Marshall, John J.; Kandel, Eric R.; Kellendonk, Christoph
Source:
Proceedings of the National Academy of Sciences of the United States of America 2008 v.105 no.41 pp. 16027-16032
ISSN:
0027-8424
Subject:
perfluorocarbons,   etc   ; adulthood; cognition; cortex; dopamine; gene expression regulation; memory; mice; neurotoxicity; patients; phenotype; planning; problem solving; receptors; schizophrenia; transgenes; transgenic animals;     Show all 17 Subjects
Abstract:
... Cognitive deficits in schizophrenia are thought to derive from a hypofunction of the prefrontal cortex (PFC), but the origin of the hypofunction is unclear. To explore the nature of this deficit, we genetically modified mice to model the increase in striatal dopamine D₂ receptors (D₂Rs) observed in patients with schizophrenia. Previously, we reported deficits in spatial working memory tasks in the ...
DOI:
10.1073/pnas.0807746105
PubMed:
18832466
PubMed Central:
PMC2572912

48. High Vapor Pressure Perfluorocarbons Cause Vesicle Fusion and Changes in Membrane Packing

Author:
Venegas, Berenice; Wolfson, Marla R.; Cooke, Peter H.; Chong, Parkson Lee-Gau
Source:
Biophysical journal 2008 v.95 no.10 pp. 4737
ISSN:
0006-3495
Subject:
perfluorocarbons,   etc   ; organofluorine compounds; vapor pressure; artificial membranes; phosphatidylcholines; medicinal properties;     Show all 6 Subjects
Abstract:
... Perfluorocarbons (PFCs) hold great promise for biomedical applications. However, relatively little is known about the impact of these chemicals on membranes. We used unilamellar vesicles to explore the effects of PFCs on membrane packing and vesicle stability. Four clinically relevant PFCs with varying vapor pressures (PP1, 294 mbar; PP2, 141 mbar; PP4, 9.6 mbar; and PP9, 2.9 mbar) were examined. ...
Handle:
10113/27742
DOI:
10.1529/biophysj.108.133496
PubMed:
18689464
PubMed Central:
PMC2576362

49. Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI

Author:
Minzenberg, Michael J.; Watrous, Andrew J.; Yoon, Jong H.; Ursu, Stefan; Carter, Cameron S.
Source:
Science 2008 v.322 no.5908 pp. 1700-1702
ISSN:
0036-8075
Subject:
perfluorocarbons,   etc   ; Primates; brain stem; cognition; humans; loci; magnetic resonance imaging; models; prefrontal cortex;     Show all 9 Subjects
Abstract:
... Models of cognitive control posit a key modulatory role for the pontine locus coeruleus-norepinephrine (LC-NE) system. In nonhuman primates, phasic LC-NE activity confers adaptive adjustments in cortical gain in task-relevant brain networks, and in performance, on a trial-by-trial basis. This model has remained untested in humans. We used the pharmacological agent modafinil to promote low-tonic/hi ...
DOI:
10.1126/science.1164908

50. Accuracy and precision in the determination of perfluorinated chemicals in human blood verified by interlaboratory comparisons

Author:
Lindström, Gunilla; Kärrman, Anna; van Bavel, Bert
Source:
Journal of chromatography 2009 v.1216 no.3 pp. 394-400
ISSN:
0021-9673
Subject:
perfluorocarbons,   etc   ; blood serum; chromatography; exposure pathways; humans; rapid methods;     Show all 6 Subjects
Abstract:
... Perfluorinated chemicals (PFCs) are analyzed in laboratories worldwide to determine human blood levels and exposure pathways. The development of the analytical technique has been rapid in the last 10 years, and prerequisites for accurate and precise determination of PFCs in human blood at low ng/g concentrations are today readily available. The main contributing factors are the improved LC-MS inst ...
DOI:
10.1016/j.chroma.2008.10.091

51. Analysis of perfluorinated chemicals in sludge: Method development and initial results

Author:
Yoo, Hoon; Washington, John W.; Jenkins, Thomas M.; Laurence Libelo, E.
Source:
Journal of chromatography 2009 v.1216 no.45 pp. 7831-7839
ISSN:
0021-9673
Subject:
perfluorocarbons,   etc   ; acetonitrile; digestion; hydrochloric acid; isopropyl alcohol; liquid chromatography; methanol; potassium; potassium hydroxide; sludge; sodium hydroxide; solid phase extraction; solvents; spectroscopy; tetrahydrofuran;     Show all 15 Subjects
Abstract:
... A fast, rigorous method was developed to maximize the extraction efficacy for ten perfluorocarboxylic acids and perfluorooctanesulfonate from waste-water-treatment sludge and to quantitate using liquid chromatography, tandem-mass spectrometry (LC/MS/MS). First, organic solvents were tested for extraction efficiency, including acetonitrile (ACN), methanol (MeOH), isopropanol (IPA), tetrahydrofuran ...
DOI:
10.1016/j.chroma.2009.09.051

52. An analytical method for the determination of perfluorinated compounds in whole blood using acetonitrile and solid phase extraction methods

Author:
Yeung, Leo W.Y.; Taniyasu, Sachi; Kannan, Kurunthachalam; Xu, Della Z.Y.; Guruge, Keerthi S.; Lam, Paul K.S.; Yamashita, Nobuyoshi
Source:
Journal of chromatography 2009 v.1216 no.25 pp. 4950-4956
ISSN:
0021-9673
Subject:
perfluorocarbons,   etc   ; acetonitrile; animals; blood; high performance liquid chromatography; ion exchange; solid phase extraction; sulfonates;     Show all 8 Subjects
Abstract:
... A method for the analysis of perfluorinated compounds (perfluoroalkyl sulfonates: C4, C6, C8, C10; perfluoroalkyl sulfinates: C6, C8, C10; perfluorooctanesulfonamide, N-ethyl perfluorooctanesulfonamide, N-ethyl perfluorooctanesulfonamidoacetate, perfluorocarboxylates: C4-C14; fluorotelomer carboxylate (7:3, 8:2) in whole blood using acetonitrile and OASIS WAX® solid phase extraction (SPE) cartridg ...
DOI:
10.1016/j.chroma.2009.04.070

53. A sensitive method for determination of a broad range of perfluorinated compounds in serum suitable for large-scale human biomonitoring

Author:
Haug, Line Småstuen; Thomsen, Cathrine; Becher, Georg
Source:
Journal of chromatography 2009 v.1216 no.3 pp. 385-393
ISSN:
0021-9673
Subject:
perfluorocarbons,   etc   ; blood serum; detection limit; epidemiological studies; equipment; humans; liquid chromatography; methanol; sulfonamides; sulfonates;     Show all 10 Subjects
Abstract:
... A sensitive and reliable method based on column switching liquid chromatography (LC) coupled to a triple quadrupole mass spectrometer (MS) has been developed for quantification of 19 perfluorinated compounds (PFCs) in serum. A volume of only 150μl serum is used and protein precipitation by methanol is the only sample preparation necessary prior to injection into the column switching system. Pseudo ...
DOI:
10.1016/j.chroma.2008.10.113

54. Association Among Serum Perfluoroalkyl Chemicals, Glucose Homeostasis, and Metabolic Syndrome in Adolescents and Adults

Author:
Lin, Chien-Yu; Chen, Pau-Chung; Lin, Yu-Chuan; Lin, Lian-Yu
Source:
Diabetes care 2009 v.32 no.4 pp. 702-707
ISSN:
0149-5992
Subject:
perfluorocarbons,   etc   ; National Health and Nutrition Examination Survey; adolescents; adults; animals; blood serum; glucose; high density lipoprotein cholesterol; homeostasis; hyperglycemia; insulin; insulin resistance; metabolic syndrome; odds ratio;     Show all 14 Subjects
Abstract:
... OBJECTIVE: Perfluoroalkyl chemicals (PFCs) have been used worldwide in a variety of consumer products. The effect of PFCs on glucose homeostasis is not known. RESEARCH DESIGN AND METHODS: We examined 474 adolescents and 969 adults with reliable serum measures of metabolic syndrome profile from the National Health and Nutrition Examination Survey 1999-2000 and 2003-2004. RESULTS: In adolescents, in ...
DOI:
10.2337/dc08-1816
PubMed:
19114613
PubMed Central:
PMC2660466

55. Comparative study on the influence of dissolved oxygen control approaches on the microbial hyaluronic acid production of Streptococcus zooepidemicus

Author:
Liu, Long; Du, Guocheng; Chen, Jian; Wang, Miao; Sun, Jun
Source:
Bioprocess and biosystems engineering 2009 v.32 no.6 pp. 755-763
ISSN:
1615-7591
Subject:
perfluorocarbons,   etc   ; Streptococcus equi subsp. zooepidemicus; agitation; dissolved oxygen; hyaluronic acid; models; oxygen; shear stress;     Show all 8 Subjects
Abstract:
... Three different dissolved oxygen (DO) control approaches were proposed to improve hyaluronic acid (HA) production: a three-stage agitation speed control approach, a two-stage DO control approach, and an oxygen vector perfluorodecalin (PFC) applied approach. In the three-stage agitation speed control approach, agitation speed was 200 rpm during 0-8 h, 400 rpm during 8-12 h, and 600 rpm during 12-20 ...
DOI:
10.1007/s00449-009-0300-6

56. Perfluorinated contaminants in fur seal pups and penguin eggs from South Shetland, Antarctica

Author:
Schiavone, A.; Corsolini, S.; Kannan, K.; Tao, L.; Trivelpiece, W.; Torres, D.; Focardi, S.
Source:
Science of the total environment 2009 v.407 no.12 pp. 3899-3904
ISSN:
0048-9697
Subject:
perfluorocarbons,   etc   ; breeding season; eggs; liver; penguins; pollutants; pups; seals; Antarctica;     Show all 9 Subjects
Abstract:
... Perfluorinated compounds (PFCs) have emerged as a new class of global environmental pollutants. In this study, the presence of perfluorochemicals (PFCs) in penguin eggs and Antarctic fur seals was reported for the first time. Tissue samples from Antarctic fur seal pups and penguin eggs were collected during the 2003/04 breeding season. Ten PFC contaminants were determined in seal and penguin sampl ...
DOI:
10.1016/j.scitotenv.2008.12.058
PubMed:
19321191

57. Sex ratio in lesser black-backed gull in relation to environmental pollutants

Author:
Erikstad, Kjell Einar; Bustnes, Jan Ove; Lorentsen, Svein-Håkon; Reiertsen, Tone Kristin
Source:
Behavioral ecology and sociobiology 2009 v.63 no.6 pp. 931-938
ISSN:
0340-5443
Subject:
perfluorocarbons,   etc   ; Larus; birds; blood; body condition; chicks; females; hatching; males; parenting; parents; pollutants; polybrominated diphenyl ethers; sex allocation; sex ratio; sons;     Show all 16 Subjects
Abstract:
... In birds, there is ample evidence that the mother can manipulate the sex of the young and produce more of the sex, which gives the highest fitness return. This has previously been documented in gulls, Laridae. Gulls are sexually size dimorphic with males larger than females, and there is good evidence that parents in poor body condition switch their investment to the smallest sex. In the present s ...
DOI:
10.1007/s00265-009-0736-3

58. Significant improvements in the analysis of perfluorinated compounds in water and fish: Results from an interlaboratory method evaluation study

Author:
van Leeuwen, S.P.J.; Swart, C.P.; van der Veen, I.; de Boer, J.
Source:
Journal of chromatography 2009 v.1216 no.3 pp. 401-409
ISSN:
0021-9673
Subject:
perfluorocarbons,   etc   ; chromatography; fish; variance;     Show all 4 Subjects
Abstract:
... The 2nd international interlaboratory study (ILS) on perfluorinated compounds (PFCs) in environmental samples was organized to assess the performance of 21 North American and European laboratories on the analysis of PFCs in water and fish. A study protocol was provided to assess accuracy, precision, matrix effects and to study the use of in-house standards. The participants used shared native and ...
DOI:
10.1016/j.chroma.2008.11.029

59. The relationship between perfluorinated chemical levels in the feathers and livers of birds from different trophic levels

Author:
Meyer, Johan; Jaspers, Veerle L.B.; Eens, Marcel; de Coen, Wim
Source:
Science of the total environment 2009 v.407 no.22 pp. 5894-5900
ISSN:
0048-9697
Subject:
perfluorocarbons,   etc   ; Ardeidae; Larus argentatus; Pica pica; bioaccumulation; diet; doves; feathers; habitats; heavy metals; indicator species; liver; pollutants; trophic relationships; Belgium;     Show all 15 Subjects
Abstract:
... Although feathers have been used successfully for monitoring heavy metals and organic pollutants, there are currently no data available on the use of feathers as indicators of perfluorinated chemical (PFC) exposure in birds. Also, no study has evaluated PFC levels in birds with different diets from different habitats. In the current study we investigated the PFC exposure of five different bird spe ...
DOI:
10.1016/j.scitotenv.2009.07.032
PubMed:
19716165

60. Non-contact protein microarray fabrication using a procedure based on liquid bridge formation

Author:
Hartmann, Michael; Sjödahl, Johan; Stjernström, Mårten; Redeby, Johan; Joos, Thomas; Roeraade, Johan
Source:
Analytical and bioanalytical chemistry 2009 v.393 no.2 pp. 591-598
ISSN:
1618-2642
Subject:
perfluorocarbons,   etc   ; cell adhesion; dimethyl sulfoxide; evaporation; human serum albumin; hydrolysis; microarray technology; polystyrenes;     Show all 8 Subjects
Abstract:
... Contemporary microarrayers of contact or non-contact format used in protein microarray fabrication still suffer from a number of problems, e.g. generation of satellite spots, inhomogeneous spots, misplaced or even absent spots, and sample carryover. In this paper, a new concept of non-contact sample deposition that reduces such problems is introduced. To show the potential and robustness of this p ...
DOI:
10.1007/s00216-008-2509-7