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- Xu, Dahai, et al. Show all 18 Authors
- TheFEBS journal 2018 v.285 no.24 pp. 4631-4645
- B-cell lymphoma; DNA; DNA-binding domains; Dysoxylum gotadhora; GATA transcription factors; animal models; apoptosis; cell lines; drugs; gene overexpression; hematopoiesis; lymphocytic leukemia; medicinal plants; oncogenes; patients; phosphorylation; protein synthesis; screening; therapeutics; transcriptional activation; China
- ... E26 transformation‐specific (ETS) gene family contains a common DNA‐binding domain, the ETS domain, responsible for sequence‐specific DNA recognition on target promoters. The Fli‐1 oncogene, a member of ETS gene family, plays a critical role in hematopoiesis and is overexpressed in diverse hematological malignancies. This ETS transcription factor regulates genes controlling several hallmarks of ca ...